laboratory animal services 2015 induction and orientation program presenters: andrew bartlett...
TRANSCRIPT
Laboratory Animal Services
2015 Induction and Orientation
Program
Laboratory Animal Services
2015 Induction and Orientation
Program Presenters:Andrew Bartlett (Manager)Nikki Reyne (Waite Facilities Coordinator)Pacita Wissell (Medical School Facility Coordinator)Tiffany Boehm (Health, Safety and Compliance Officer)Faye Gardner (Office Manager)Xavier Curlija (Admin. Officer)Denise Noonan (Animal Welfare Officer)
2.10pm Monday 23rd February 2015Stirling Lecture Theatre, Ground Floor Medical
School South
Vision and Values Policy Framework/Partnership LAS organisational structure Animal Welfare and Ethical Conduct
Animal Welfare Officer Administrative procedures/policies
Office Manager Standard Operating Procedures (SOPs)
Facility Coordinators Health, Safety and Compliance Question time
Program StructureProgram Structure
VisionVision
Laboratory Animal Services will support the University of Adelaide’s biomedical research community through the delivery of best practice animal
husbandry and the provision of world standard laboratory animal products and services, whilst
maintaining a commitment to the principles of the
AUSTRALIAN CODE FOR THE CARE AND USE OF ANIMALS FOR
SCIENTIFIC PURPOSES - 8TH EDITION 2013
Values/ObjectivesValues/Objectives
Laboratory Animal Services will…
…demonstrate a commitment to the purpose of the AUSTRALIAN CODE FOR THE CARE AND USE OF ANIMALS FOR SCIENTIFIC
PURPOSES, specifically, “…to ensure the ethical and humane care and use of animals used for scientific purposes”.
…strive for continuous improvement in animal husbandry through the training and development of the animal care officers and investigators.
…develop a customer focus by providing investigators with professional, timely and effective support.
Policy FrameworkBIOMEDICAL RESEARCH
Policy FrameworkBIOMEDICAL RESEARCH
The Client
PREVENTION OF CRUELTY TO ANIMALS ACT 1985
AUSTRALIAN CODE FOR THE CARE AND USE OF ANIMALS FOR SCIENTIFIC
PURPOSES - 8TH EDITION 2013
ANIMAL USERS HANDBOOK
ANIMAL ETHICS COMMITTEE
BIOMEDICAL ANIMAL RESEARCH ADVISORY GROUP
ANIMAL WELFARE OFFICE
LABORATORY ANIMAL SERVICES
PoliciesImportation/ExportTransportationAcquisitionQuarantineAnimal housing standardsTrainingBreeding/Weaning (rodents)
ProtocolsAnaesthesiaEuthanasiaContingency plansSPF rodent productionAnimal health surveillanceAEC applicationsSecurity procedures
Standard Operating Procedures(SOPs)
Research Integrity + Animal Welfare
Traffic flowsAnimal husbandry
Technical proceduresFacility maintenance
Housekeeping
The “Partnership”The “Partnership”
Animal Technician and the Biomedical Researcher
Priorities AT BmRAnimal Welfare Research Integrity Customer Service Effective Communication
The complexity of the environment in which we work can distort our perspectives at a given
point in time BUT our objectives should always be the same!!
Laboratory Animal Services 2015 Organisational Structure
Pro-Vice Chancellor(Research Operations)
Richard Russell AM
Animal Welfare Officer11154 Denise Noonan (HEO9)
Manager, Laboratory Animal Services4642 Andrew Bartlett (HEO10)
Advisory Groups
Facility Coordinator: Waite Campus2428 Nikki Reyne (HEO6)
Facility Coordinator: Medical School2775 Pacita Wissell (HEO6)
Senior Animal Technician14274 Luke Ragless (HEO4)
Senior Animal Technician14075 Melissa Thomas (HEO4)
Senior Animal Technician1909 Rebecca Arbon (HEO4
Senior Animal Technician2425 Sarah Fisher (HEO4)
Senior Animal Technician3104 Alice Parmiter (HEO4)
Office Manager2876 Faye Gardner (HEO5)
Animal Technician10955 Sue Pinkus (HEO3)
Animal Technician4026 Nathan Stringer (HEO3)
Animal Technician16707 Despina Livadiotis (HEO3)
Health, Safety & Compliance Officer17269 Tiffany Boehm (HEO5)
Animal Technician16696 Faye Bone (HEO3)
Senior Animal Technician4027 Chantal Didenko (HEO4)
Animal Technician 15805 Bud Duncan (HEO3)
Animal Technician16874 Jaimee Spurr (HEO3)
Senior Animal Technician11307 Xavier Curlija (HEO4)
Senior Animal Technician13983 Jessica Church (HEO4)
Animal Technician4615 Paige Farrow (HEO3)
Administrative Officer12925 Susan Smith (HEO3)
Animal Welfare Officer
Dr Denise Noonan Mobile: 0421 615 147 Phone: 831 34107 E-mail: [email protected] Office: DV-C & V-P Research, Level 14, 115
Grenfell St. http://www.adelaide.edu.au/animalwelfar
e/
Documents relevant to scientific use of animalsDocuments relevant to scientific use of animals
http://www.nhmrc.gov.au/guidelines-publications/ea28 http://www.australiananimalwelfare.com.au/home
http://www.legislation.sa.gov.au/LZ/C/A/Animal%20Welfare%20Act%201985.aspx
Animal Welfare Officer Duties
Promote awareness of and adherence to the Australian Code for the Care and Use of Animals for Scientific Purposes (2013) http://www.nhmrc.gov.au/guidelines-publications/ea28
Promote the 3 Rs –Replace, Reduce, Refine Provide clinical veterinary services for research
animals Monitor animal holding facilities Provide advice to
Researchers Animal Care Staff The University Animal Ethics Committees
University of Adelaide processes regarding approval for the ethical use of animals
University of Adelaide processes regarding approval for the ethical use of animals
Animal Ethics Committees Medical Committee Secretary: Tim Anson (ext. 32980) Science Committee Secretary: Helen Malby (ext. 34014) http://www.adelaide.edu.au/ethics/animal/
Compulsory Animal Ethics Induction & Refresher Training Courses
The use of animals in science: ethical considerations University of Adelaide North Terrace, Bonython Hall Wednesday 11th March 2014, 8.30am-1.00pm &
2pm-4pm Register on-line TODAY would be appreciated for
planning purposes! http://www.adelaide.edu.au/ethics/animal/training/
Optional Practical Training in common lab animal procedures -Handling, injection, blood collection
Mouse, Rat and Introduction to Anaesthesia and Surgery of Rodents
Venue: Med School South Teaching Laboratory S210 Register on-line TODAY link for on-line registration at http
://www.adelaide.edu.au/animalwelfare/training-workshops/
(All queries to Dr Denise Noonan)
Australian CodeAustralian Code
Responsibilities of Investigators and Teachers
Personal responsibility for all matters relating to the welfare of their animals. the responsibility of investigators
extends over all facets of the care and use of animals in projects approved by the ethics committee.
written AEC approval must be obtained before a project can begin, all AEC directives must be complied with
Australian CodeAustralian Code
Responsibilities of Investigators and Teachers
Records of animal use and monitoring must be maintained and available for audit, including:
Clinical Record Sheets Details of animal treatments including
anaesthetics, analgesics, experimental treatments and doses given
Numbers of each species and strain of animal used
Breeding colony production records Post mortem findings and adverse
event reports
Australian CodeAustralian CodeResponsibilities of Investigators and Teachers
Clinical Record Sheets to be held in the room where the animals are held throughout their scientific use.
LABORATORY ANIMAL SERVICES
CLINICAL RECORD SHEET (RAT & MOUSE)
RESEARCHER NAME: _________________________ ID NUMBER: ______________________________________ DEPARTMENT: ______________________________ ANIMAL ETHICS NUMBER: __________________________
DA
TE
DU
LL
/RU
FF
LE
D
CO
AT
PO
OR
PO
ST
UR
E/
HU
NC
HE
D
PA
LE
OR
SU
NK
EN
E
YE
S
CH
AN
GE
IN
B
EH
AV
IOU
R
RE
DU
CE
D F
OO
D/
WA
TE
R IN
TA
KE*
DE
HY
DR
AT
ION
DIA
RR
HO
EA
SQ
UE
AL
ING
W
HE
N H
AN
DL
ED
RE
LU
CT
AN
T T
O
MO
VE
WE
IGH
T L
OS
S
OT
HE
R
CO
MM
EN
TS
TO
TA
L S
CO
RE
SIG
NE
D
YES = 1 Scores of 3 require the animal to be checked 3 times per day NO = 0 Scores of higher than 3 require Animal Welfare/ Veterinary advice Scores higher than 4 require Euthanasia
* Where known in single housed animals
Key Resource: Animal User’s Handbook
http://www.adelaide.edu.au/ethics/animal/guidelines/animalusershandbook/
Global Context: Animal Activism
Responses to Animal Activism
UK Responses to Animal Activism
Administrative Support
Faye Gardner Office Manager
Sue Smith Administrative Assistant
Xavier Curlija Administrative Assistant
Ph. 35340Fax. 34342Room: S643Email:[email protected]
Administrative ProceduresAdministrative Procedures
General Issues Web page http://www.adelaide.edu.au/animal_services/
Communication channels interpersonal methods stakeholder register Blog
Administrative ProceduresAdministrative Procedures
Involving animal use: Ethics approval Animal ordering/ technical assistance requests
http://www.adelaide.edu.au/animal_services/products/ordering.html
Calcium (Room/Equipment Booking system) http://www.adelaide.edu.au/animal_services/
Fee structure Internal/external clients
Invoicing
Australian CodeSection 2. Responsibilities
Australian CodeSection 2. Responsibilities
The Facility Manager Responsibilities are: obtain written approval from the AEC for activities
related to care and management of animals in the facility and regularly review these activities.
ensure activities are implemented and conducted ensure all people involved in animal care
understand their responsibilities seek AWO advice and ensure advice given is
followed Implement QA programs and regularly review these
programs in accordance with current best practice Coordinate between researchers and LAS staff Report to the AEC
Australian CodeChapter 2.5, Responsibilities
Australian CodeChapter 2.5, Responsibilities
The Animal Technician Responsibilities are: support animal wellbeing avoid or minimise harm, including
pain and distress ensure provisions for animals at the
conclusion of their use and disposal of carcasses and waste material
ensure records are maintained
Medical School FacilityMedical School Facility Standard Operating Procedures
1. Traffic Flows
- PC2 Barrier North (Clean Rooms & Bio-Exclusion)- PC2 Barrier South (Bio-Exclusion & Bio- Containment)- PC2 Isolation Room 638a- Conventional (Rodents + PC1 rodent room)
- Conventional (Sheep)
- Disciplinary action for breach of
protocol
Medical School FacilityMedical School Facility
Standard Operating Procedures (cont…)
2. Gowning requirements
3. Theatre/Anaesthetic Machine Booking
4. House keeping
5. Animal Care
6. Animal Handling
Medical School Facility
Technical Assistance – what the Medical School Facility can provide
Maintain GMO and inbred breeding colonies to OGTR regulations.
Tail biopsies Time mating (including plug checking) Identification Orbital eye/facial vein blood collection Cardiac blood collection Gavaging S/C, I/M, I/P injections of all species Tail vein injection Jugular vein injecting (sheep) Anaesthetising all species (including pre and post operative
care)
Waite Campus Animal Facilities
Waite Campus Animal Facilities
SPF Barrier Production Inbred Strains available: C57/Bl6,
BALB/C, CBA, Nude, & DA Outbred: Swiss, SD, AW, HW Hybrid: CBA F1 Mice available from birth to 8-
10weeks Rats available from birth to 6
weeks Large orders – advance notice Standing and advance orders are
given priority Ordering by age / weight
[email protected].: 37363
Waite Campus Animal Facilities
SPF Barrier Production Time Matings
3 days notice prior to mating Day 0 is plug day No guarantee that the animals
will mate on the specified day No guarantee that the animals
will be pregnant when a plug is found
QA Program routine 6 weekly testing results available online
Roseworthy Campus Animal Facilities
Livestock Research Centre (LRC) 56 pens Additional 20 pens able to
be converted to 10 double size pens
Surgical suite Booking of pens through LAS
Small Animal Research Facility
3 animal holding rooms plus procedure room
Compliance
OGTR (Office of the Gene Technology Regulator)
AQIS (Australian Quarantine Inspection Service)• DAFF (Department of Agriculture, Fisheries and
Forestry)
Legal and Risk
Health and Safety
Genotrack
Office of the Gene Technology Regulator -
OGTR Cage Cards Must include IBC Number
Online training
PC1 Medical School Conventional Room 658 and 644
PC2 Medical School All Barrier and Containment Rooms Post Mortem Room 654 Isolation Room 638
Gowning Requirements
http://www.ogtr.gov.au/
Department of Agriculture, Fisheries and Forestry –
DAFFFormally Australian Quarantine Inspection Service (AQIS) AQIS import certificate required before import
Notification to Facility Co-ordinator Current Ethics approval OGTR licence IBC Number (if Genetically Modified) In-house Import Form Health reports
Waite Campus Xenopus room
Medical School Room 632a Barrier Containment and Isolation
Room 638
Legal Compliance Animal Welfare Act (1985)
Controlled Substances Act (1984)
Dangerous Substances Act (1979)
Gene Technology Act (2000)
Livestock Act (1997)
Quarantine Act (1908)
Radiation Protection and Control Act (1982)
Health, Safety and Wellbeing
Health, Safety and Wellbeing
Branch Policy
Hazards associated with animal work manual handling bites, scratches and kicks research activity
Evacuation Procedures animal experiments alarms emergency exits
Client Responsibilities
Evacuation Points
Genotrack Breeding Colony Maintenance Software
breeding weaning matings statistics ethics health care
Web based software need to be issued with a licence and
password
Available for researchers to use
QuestionsQuestions
…hmmmmm?