Lecture 12

• Format of the final examination

• Review

Available for office hours:

Make an appointment,

or drop by anytime and see if I am available.

What can I bring to the Final?• Dictionary

• The paper and notes on the paper. Any paper (review or primary) you have consulted, and notes on that paper.

• One textbook if you think that will help.

Format of the final• Essay/short answer

• Designed to be written in 2 hours but 3 are given.

• All answers must be in full sentences.

• All answers must answer the question asked. If the extraneous material written is wrong/inappropriate, marks will be lost.

• Answers must be written clearly, concisely and completely.

• Answers must be written in pen not pencil.

Format of the final• Excluded from the examination room are

cell phones, laptops, and other communication devices.

Advice• Read the question carefully and slowly.

• Write down an outline to your answer before writing the final answer.

• Look at the type of questions I have asked in the past and see whether you can ask and answer them on this paper before the exam.

• Forming a study group may be helpful.

• Remember I am no expert on the assigned paper. I have only read this paper twice so far and have set the exam. I can’t blindside you.

What I can ask

• Anything in the paper: technical or intellectual.

• Anything in other papers that I deem necessary for you to know in order to understand what the authors have done.

• The key is to question your understanding of the material in the paper. Approach your reading in a Socratic manner.

Review example 1

Review example 2

• The following is figure 4 panel D from the Drosophila sexual behavior paper (paper 3).

• Explain the following panel in detail: what is being shown, and how the data supports the conclusion made from this data.

• Imagine what they have done.

Panel D of Figure 4 shows that females will mate withmale flies that are engineered to express female pheromones.The female courtship index of fruC fruF fruM and frutrafemales was assayed when mated with oeGAL4, UAStra,and oeGAL4/UAStra males. The female courtship indexincreased significantly with males that expressed femalepheromones. This evidence supports the author’s conclusion the fru is a behavioral switch gene.

It is a picture of a girl or young women holding a ferret. She is looking to her left and has big hands.She is wearing an embroidered dress and a long necklace.

Panel D of Figure 4 shows that females will mate withmale flies that are engineered to express female pheromones.The female courtship index of fruC fruF fruM and frutrafemales was assayed when mated with oeGAL4, UAStra,and oeGAL4/UAStra males. What is the point of the layout of the data in the figure? The female courtship indexincreased significantly with males that expressed femalepheromones. This evidence supports the author’s conclusion the fru is a behavioral switch gene.

Panel D of Figure 4 shows that females will mate withmale flies that are engineered to express female pheromones.The female courtship index of fruC fruF fruM and frutrafemales was assayed when mated with oeGAL4, UAStra,and oeGAL4/UAStra males. The female courtship indexincreased significantly with males that expressed femalepheromones. This evidence supports the author’s conclusion the fru is a behavioral switch gene. How does this evidence support the author’s conclusion?

Panel D of Figure 4 shows that females will mate withmale flies that are engineered to express female pheromones. How does this engineering work; what are its principles?The female courtship index of fruC fruF fruM and frutrafemales was assayed when mated with oeGAL4, UAStra,and oeGAL4/UAStra males. The female courtship indexincreased significantly with males that expressed femalepheromones. This evidence supports the author’s conclusion the fru is a behavioral switch gene.

I guess it would be helpful if you had looked up Ferveur et al., 1997. The answer is kind of neat.

Good Luck