level of tumor protein indicates chances cancer will spread and structural details of a key protein...
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CAROLINA GONZALEZ SERNAMOLECULAR BIOLOGY
MEDICINE STUDENTIII SEMESTER
UPB
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Corte intrducción
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•High levels of a particular protein in cancer cells are a reliable indicator that a
cancer will spread
•. CPE-delta N protein, a variant of CPE, was present in high amounts in tumors that
had spread
•Cancer cells can break away from a primary tumor and spread, or metastasize, to other parts of the body, where they form
new tumors
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•"Testing for CPE-delta N, if combined with existing diagnostic methods, offers the possibility of more accurately estimating the chances that a cancer will spread," said Alan E. Guttmacher, M.D
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•The researchers tested for CPE-delta N indirectly, by measuring levels of a molecule that assists in manufacturing the protein. RNA (ribonucleic acid) works with the information in a gene to make a particular protein, in this case, CPE-delta
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• Sam 68 carry out important tasks in the signal-regulated processing of genetic information
and its translation into protein
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• Sam68 regulates specific processes linked to the cell cycle and apoptosis and plays a key role in the pathogenesis of cancer.
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With this news we can see the importance of knowing the molecular structure of a protein and the role that each part of this structure plays in a circuit superior organization..
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1. Poder establecer Tratamientos mas enfocados y específicos para pacientes con cáncer que actúe de acuerdo a las características del
mismo y por ende optimizar el resultado A favor del bienestar del paciente.
2. Proponer nuevas medicamentos que neutralicen expresiones no favorables para el tratamiento de el cáncer.
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1. Establecer molecularmente el foco del problema que en rute una búsqueda en pro de
reparar alteraciones estructurales para que no se afecte la funcionalidad de una proteína que conlleve a el desequilibrio de todo un sistema
2. gran beneficio en la prevención de una pandemia Como lo es hoy el cáncer
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• MARTINES S., Lina María. Biología Molecular. 6.ed. Medellín : UPB, 2011. 105p.
• Science News. Structural Details of a Key Protein for Cellular Signal Transduction [ en línea ]. <Disponible http://www.sciencedaily.com/releases/2011/02/110201122218.htm> [ consulta : 17 FEB. 2011]
• Science News.Level of Tumor Protein Indicates Chances Cancer Will Spread Transduction [ en línea ]. <Disponible http://www.sciencedaily.com/releases/2010/09/100910083350.htm > [ consulta : 17 FEB. 2011]
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