life sciences entrepreneur certificate. $10m, 3 ½ year competition to develop a handheld medical...

LIFE SCIENCES ENTREPRENEUR CERTIFICATE


• $10M, 3 ½ year competition to develop a

handheld medical diagnostic device

• De-skill medicine to enable affordable, accessible

health care

• Global impact on mobile healthcare

• TSI directly supports SDSU X-Team success


SDSU building 'Star Trek' tricorder

By Gary Robbins8:35 p.m.April 26, 2013

The X Prize Foundation last year created a long-term, worldwide contest …Qualcomm Tricorder X Prize has drawn hundreds of competitors, including at least 10 teams from San Diego County. The latest competitor is one of the region’s academic powerhouses: San Diego State University.

http://www.utsandiego.com/staff/gary-robbins/

http://www.qualcommtricorderxprize.org/

http://www.utsandiego.com/news/2013/apr/26/startrek-tricorder-sdsu/all/?print#lb-photo1000352


• Forward-looking

• Inexpensive, integrated software solutions

• Focus on user experience

• Commercial partner with hardware developers

TrossSolutions Inc.


• NASA in the 60s

• Like ‘race to space’, Apollo program

• That goal required a variety of new and integrated technologies

• We developed a portfolio of commercializable technologies to build the Tricorder and win the XPRIZE


Competition Launch

(Jan 2012)

Event(Jan 2012)

Event(Jan 2012)

SDSU Xteam on ABC News(Apr 2013)

SDSUEnters Semi-Finals

(Nov 2013)

Universal Driver Hub (Q-

Bit)Complete(Nov 2013)

TODAY

Prototype Submittal(Feb 2015)

Finals(Q2 2015)

XPRIZE Milestone & Events


Q Bit Devices


• Q-Bit – Universal Driver Hub:

• Simultaneously connect up to 7 Bluetooth devices

• Identify type of device and data stream

• Multiplex data stream in one buffer

• Display multi device data on one single platform

• Software runs on all android platforms

• Full input/output device mgmt.

• Synchronization

TRICORDER

Diagnostic Medical Device for Home and Clinical Use

Problem

• Inadequate consumer access to rapid, effective medical diagnostics

• High cost and lengthy processing in lab industry • High cost of diagnostic equipment

Investment andExit Strategy

• $10 Million Sought

• Sale to Strategic Partner• Initial Public Offering

Solution

• We provide low-cost, effective Point-of-Care (POC) medical diagnostics

•We integrate with existing wireless technology

Value Proposition

• Increased access to rapid, quality medical diagnostics

• Decreased cost of diagnostic access and equipment

IP Strategy• IP in progress for software and trademarks• Professional and Pro Bono legal counsel from TechLaw LLP• Research and license agreements with strategic partners

BUSINESS SUMMARY

Competitive Differentiation

• Flexible Software and Device Integration

• Agnostic to Manufacturer

• Scalable and Expandable

• User Data Portability and Security

PROBLEM: CURRENT HOME TECHNOLOGY

PROBLEM: CURRENT CLINICAL TECHNOLOGY

SAMPLE PROCESSING

(1-2 weeks) @ service provider

Setup appointment(1-2 weeks)

Feedback to Patient(~1 month)

SOLUTION: TSI TRICORDER

Shorten time to care or intervention:

• Home application - Tricorder can diagnose a

number of common diseases at home

• Clinical application – Tricorder can reduce time to

attain sample analysis (from 1 month to 20-30

minutes)

• Reduces time to see physician or attain intervention

(drug / surgery or more in-depth analysis)

TRICORDER SYSTEMTRICORDER SYSTEM:

• Multiple LASER systems

• Gas Sensors• Microfluidics system• Software: Agnostic

Device Integration, Onboard Sample Analysis

• Smartphone

• 3rd Party Wireless Vital Sign Sensors

(Masimo, Zephyr, etc.)

Sample INPUT (fluids):

• Blood• Sputum• Urine

AND

• Vital Signs (Wearable Sensors)

TRICORDER OUTPUT:

• Cholesterol• White

Blood Cell Count

• Glucose• Protein• Amino Acid• Blood

Count• Biomarkers• Vitals• Disease

Diagnosis• Etc. (214

tests currently in line to assess)

HOME AND CLINICAL DATA SECURITY

• User data encrypted and secured with private key

• All data encrypted, from sensors to reports

• Data transferred via encrypted, secured tunnels

• “Your data is your own”, we don’t see user data

• Designing for FDA and HIPAA compliance

TRICORDER BENEFITS

• Easy-to-load disposable sample cartridges

• Clinical unit will be CLIA waived (can operate

anywhere)

• Targeted WEEE, REACH, RoHS compliant as well as

FDA / CE Marking

• Improvement in quality of data / time for data

delivery for analysis

• Remove a layer of costs (Sample Service provider) to

Healthcare

• Integrated system for ease of use / share Data to

Cloud

• Increased healthcare accessibility

TRICORDER BENEFITS

Home Use Clinical Office Use

Patient

• Ability to make an more informed decision

• Ease in Data Management• Reduced time to reach

healthcare service • Increased accessibility to

anywhere with power and wireless network

• Ability to analyze patient sample on same visit

• Reduction of wait time for Health Care assessment and ultimately intervention

• Reduce cost for sample testing

Doctors

• Ability to monitor patients at home

• Reduction of visits to urgent care and emergency room

• Provide greater options to Patient

• Increase revenue for sampling in office

• System Assists doctors to be close out patient cases sooner

COMPETITIVE ANALYSISPoint of CarePlayers Systems Test Methods Disease Detection Continuous

MonetoringInteroperability Portability Scalability Seamless InterfaceSecurity

Abbot i-STAT® Blood Distributed Health Sense* Vitals Scanadu Scout* Vitals Sotera VisiMobile Vitals TrossSolutions TSI Medical Tricorder Vitals, Fluids Life Watch CAM Vitals CAM: Cardiac Arrhythmia Monitoring

Indirect Players Systems Test Methods Versatility Technology Portability Scalability

Theranos Nanotainer Lab methods Consumer Physics SCiO spectroscopy BD Biosciences BD Stemflow™ ICF TellSpec TI's DLP 0.45 spectroscopy TrossSolutions Que system Vitals, Fluids Versatility: Measure a variety of samples in a variety of environments and packaging with just one unit

*Claims

ICF:Intracellular flow cytometry

TRICORDER MARKET

$21.1 B

Market

Clinical testing performed annually•Standard Testing – $15.3B•Anatomical Pathology – $5.8B•Largest competitors: Quest Diagnostics / Laboratory Corporation of America Holdings

$26 BMarket

Mobile Health Apps Market – $26B (2017 estimate)•Fitness Device– $10B•Wellness and Nutrition – $9.3B•Wireless Medical Device– $6B•Largest competitors: emerging market, no market leader currently

TRICORDER TIMELINE

Investment:$1,000,000

Proof of Concept Prototype

-------12 months ------

Investment:$9,000,000

Product DevelopmentCLIA Waiver Approval

------- 24 -36 months ------

Product DevelopmentFDA Approval

-------36 - 48 months -----

Home MarketEntry

R&D marketEntry

Clinical Revenue

Clinical marketEntry

Partnerships Advanced Laser Companies

Microfluidics Companies

Medical Device Companies

Mobile Device Companies

Design & Prototyping

Companies

XPRIZE

San Diego State University

TechLaw LLP

COMPANY TRACTION

ORG CHART Core Team

Bioscience Team

Software Team

Engineering Team

Bus-Dev Team

Graphics Team

PR/Media Team

Strategic Partners

SDSU X-Team comprises over 50 team members from all disciplines, including SDSU students, staff, faculty and strategic partners.

• 12 MBAs• 12 Programmers• 10 PhDs• 9 Graphic Designers• 4 Engineers• 3 MDs• 2 PR Specialists• 1 ScD• 1 JD

CORE TEAM

•CEO: (seeking successful bio-tech executive)

•President & Team Captain: Lambert Ninteman•Exec VP & Quality: David Wong•VP Software: Scott Lindeneau•Product Manager: Ian Winfield•Lead Bio-engineer: Gene Rayford•Business Development: Gaurav Parbat•Media Relations: Alexandra Swanland

•Chief Medical Adviser: Dr. Roberta Gottlieb (Cedars-Sinai)•Senior Biomedical Adviser: Dr. Nick Gekakis (SDSU)•Senior Laser Adviser: Sam Crivello (Daylight Solutions)

WHAT MAKES US THINK WE CAN DO IT..?• Amazing Team

• Superlative Relationship with SDSU

• Great Strategic Partners

• XPRIZE, media coverage

EXIT STRATEGY

Liquidity to Shareholders: • By exiting via a sale to a strategic acquirer in three

to four years

• Or potentially via an Initial Public Offering (IPO)

Ideal Candidate: • Global healthcare, bio-tech or telecommunication

group pursuing a consolidation strategy to maintain market leverage

• BD, ThermoFisher, Abbott, J&J, 3M, HP, Sony, Google

BACKUP SLIDES

Clinical Use (Number of Businesses)

Hospitals in US 3,013

Nursing Care Facilities in the US 8,288

Specialty Hospitals in the US 585

Home Care Providers in the US 303,440

Primary Care Doctors in the US 131,572

Specialty Doctors in the US 218,417

Total 665,315

CUSTOMERS - CLINICAL

life sciences entrepreneur certificate. $10m, 3 ½ year competition to develop a handheld medical...

Documents

security slide

xprize slide

month slide

synchronization slide

indepth analysis slide

clinical use slide

sdsu xteam success slide

tsi tricorder