Life Sciences Trend Analysis 2013

FRANCE

About Us

The following statistical information has been obtained from Biotechgate. Biotechgate is a global, comprehensive, Life Sciences database encompassing the Biotechnology,Pharmaceutical and Medical Device industries. www.biotechgate.com

The French Biotech Database is a part of the global Biotechgate and is brought to you in partnership with APIM - the Lille Métropole Development Agency; assisting companies to establish and grow thier Business in France from Lille. www.frenchbiotech.com

Biotechgate is owned and operated by Venture Valuation AG, a Zurich based company specializing in independent assessment and valuation of technology-driven companies in high growth industries, such as the Life Sciences (Biotech, Pharma, Medtech), ICT, high-tech, Nanotech, Cleantech and Renewable energy. www.venturevaluation.com

Status of the Sector

2012 Statistics

France 2013 Statistics

392 Total Biotech Companies 685

91 Biotech - Therapeutics 159

242 Biotech - R&D Services 349

59 Biotech - Other 177

96% Percentage of SME's 94%

6%Percentage of Publicly Owned

Companies4%

USD 24 M (2011)

Financing/Capital RaisedUSD 150 M

(2012)

204 Licensing Opportunities 342

Key Activities of Biotechnology Companies

Historical DataSubsector 201

32012

Environment 4% 1%Contract Research and Manufacturing

15% 19%

Diagnostics and Analytical Services

17% 18%

Genomics and Proteomics 5% 7%Food and Nutraceuticals 4% 3%Other Services and Suppliers 26% 25%Therapeutics 13% 13%Other 16% 14%

2013 Data

Contract Re-

search and

Manu-factur-

ing15%

Diagnostics and Analyt-ical Services

17%

Envi-ronment

4%

Food and Nu-traceu-ticals4%

Ge-nomics

and Pro-teomics

5%

Other Services

and Suppli-

ers26%

Therapeutics13% Other

16%

2013 Data

Company Foundation Timeline

19951996

19971998

19992000

20012002

20032004

20052006

20072008

20092010

20112012

20130

5

10

15

20

25

30

35

1 3 3

10 106 5

116

127

11 10 84 6

2

75

611

9

17

19

10

18

14

13

175

1313

98

5

5

4

6

2

1

3

6

43

3

56

1 1

1

Biotechnology - Therapeutics and DiagnosticsBiotechnology / R&D ServicesBiotechnology - other

Year

No.

of

Com

panie

s F

ounded

Company Ownership

Historical DataSubsector 201

3201

2Private/ Independent

84% 87%

Public 4% 6%Subsidiary 12% 7%

Private / inde-pendent

85%

Public4%

Subsidiary12%

2013 Data

Sources of Company Foundations

Historical DataCompany Foundation 2013 2012Independent foundation 57% 70%Spin-off from company 2% 3%Spin-off from public institution / NPO 4% 9%Spin-off from university 3% 3%Subsidiary 11% 10%Other 4% 4%

Undisclosed18%

Indepen-dent

founda-tion57%

Merger1%

Spin-off from company2%

Spin-off from public institution / NPO

4% Spin-off from

univer-sity3%

Subsidiary11%

Other4%

2013 Data

Number of Employees

Historical DataNo. of Employees 2013 20121-10 32% 26%

11-50 49% 56%

51-200 15% 14%

Greater than 200 4% 6%

1-10:32%

11-50:49%

51-200:15%

201+:4%

2013 No. of Employees

Products in the Pipeline

2013

2012

2013

2012

2013

2012

2013

2012

Pre

clin

ical

Phase

IPhase

II

Phase

III

0 20 40 60 80 100 120 140 160

136

105

53

37

73

58

20

15

No. of Products

Financing Rounds in France & 3 Major Financing Rounds

Financing for 2012/2013 Private Biotech Companies

Major Financings in 2012/2013

SectorUSD M

Magnisense SARL Biotech – R&D 59

Poxel SABiotech – Therapeutics &

Diagnostics17

TxCellBiotech – Therapeutics &

Diagnostics16

2007 2008 2009 2010 2011 20120

50

100

150

200

0

5

10

15

20

Financing ValueNumber of Financings

Half Yearly

Fin

an

cin

g V

alu

e

US

D M

Nu

mb

er

of

Fu

nd

ing

R

ou

nd

s

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Terms of Use

The “French Life Sciences Trend Analysis” is based on data entered in the Biotechgate Database available at www.biotechgate.com. The statistics and graphs in this presentation are based on figures and information entered in this database and we do not guarantee any accuracy hereof.

The use of the figures and graphs provided in this report is free of charge for any presentations as long as www.biotechgate.com is clearly cited as the source. For all other uses please contact us for terms and conditions.

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