m. jorge guimarães, m.d., ph.d. founder & president of alert · portugal 2007 cotec innovation...

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www.alert-online.com October 8, 2019 PERSONAL INFORMATION Address ALERT Life Sciences Computing R. Daciano Baptista Marques, 245 4400-617 Vila Nova de Gaia, Portugal Contacts +351 96 890 28 44 [email protected] PROFESSIONAL EXPERIENCE & EDUCATION PATENTS 2003 Mammalian selenophosphate synthetase - Patent number: 6586217. Abstract: Selenophosphate synthetase protein from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this protein. Methods of using these reagents and diagnostic kits are also provided. Inventors: M. Jorge Guimarães, J. Fernando Bazan, Albert Zlotnik. 2001 ALERT ® Emergency Room Tracking (IGAC - Inspeção Geral das Atividades Culturais, Portugal, 2001) 1999 Purified mammalian nucleobase permeases; nucleic acids; antibodies. Patent number: 5858707. Abstract: Nucleobase permeases from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids hybridizing to or encoding such proteins. Methods of making and using said reagents and diagnostic kits are also provided. Inventors: M. Jorge Guimaraes, J. Fernando Bazan, Terrill K. McClanahan, Albert Zlotnik. M. Jorge Guimarães, M.D., Ph.D. Founder & President of ALERT AWARDS AWARDS ATTRIBUTED TO ALERT LIFE SCIENCES COMPUTING 2010 Professional Merit Gold Medal Award, Gaia Municipality, Portugal 2007 COTEC Innovation Award 1999 - to date Founder & President, ALERT Life Sciences Computing, S.A. 1997 - 1999 Post-doc in Gene Therapy, Genetics Department, Stanford University, U.S.A. 1993 - 1997 Visiting Scientist, DNAX Research Institute, Palo Alto, U.S.A. Ph.D. in Medicine, Faculty of Medicine, University of Porto, Portugal 1991 - 1993 Internship in Medicine, Hospital de S. João, Porto, Portugal 1985 - 1991 Degree in Medicine, Faculty of Medicine, University of Porto, Portugal 2009 Distinction in Professional Services, Rotary International 2008 Medal of Honor from the Portuguese Business Association (AEP) 2008 Ernst & Young Emerging Entrepreneur of the Year Award 2000 Citizen of Merit of Viana do Castelo, Portugal 1998 BIAL Grand Prize in Medicine 1997 Medical Genetics Prize Jacinto Magalhães MOST IMPORTANT PUBLICATIONS - Guimarães, M.J. Discovery of non-rigid eggs and hatchlings in two Archaeopteryx fossils. Paleo & Life, Abstracts of the 90th Annual Meeting of the Palaontologische Gesellschaft, Munich 2019, 53 - Guimarães, M.J. The Rediscovery of Archaeopteryx (Vol. II): Archaeopteryx’s Hatchlings (ALERT Life Sciences Computing, Portugal, 2018). On sale at amazon.com - Guimarães, M.J. The Rediscovery of Archaeopteryx (Vol. I): Non-Rigid eggs in the Bird Lineage (ALERT Life Sciences Computing, Portugal, 2018). On sale at amazon.com - Guimarães, M.J. et al. Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in selenocysteine metabolism? Proc Natl Acad Sci U S A. 1996, 93: 15086-91 - Guimarães, M.J. et al. Molecular cloning and characterization of lysosomal sialic acid O-acetylesterase. J Biol Chem. 1996, 271: 13697-705 - Guimarães, M.J. et al. A new approach to the study of haematopoietic development in the yolk sac and embryoid bodies. Development. 1995, 121: 3335-46 - Guimarães, M.J. et al. Differential display by PCR: novel findings and applications. Nucleic Acids Res. 1995, 23: 1832-3

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Page 1: M. Jorge Guimarães, M.D., Ph.D. Founder & President of ALERT · Portugal 2007 COTEC Innovation Award 1999 - to date Founder & President, ALERT Life Sciences Computing, S.A. 1997

www.alert-online.com

October 8, 2019

PERSONAL INFORMATIONAddressALERT Life Sciences ComputingR. Daciano Baptista Marques, 2454400-617 Vila Nova de Gaia, Portugal

Contacts +351 96 890 28 [email protected]

PROFESSIONAL EXPERIENCE & EDUCATION

PATENTS2003Mammalian selenophosphate synthetase - Patent number: 6586217. Abstract: Selenophosphate synthetase protein from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this protein. Methods of using these reagents and diagnostic kits are also provided. Inventors: M. Jorge Guimarães, J. Fernando Bazan, Albert Zlotnik.

2001ALERT® Emergency Room Tracking (IGAC - Inspeção Geral das Atividades Culturais, Portugal, 2001)

1999Purified mammalian nucleobase permeases; nucleic acids; antibodies. Patent number: 5858707. Abstract: Nucleobase permeases from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids hybridizing to or encoding such proteins. Methods of making and using said reagents and diagnostic kits are also provided. Inventors: M. Jorge Guimaraes, J. Fernando Bazan, Terrill K. McClanahan, Albert Zlotnik.

M. Jorge Guimarães, M.D., Ph.D.Founder & President of ALERT

AWARDS

AWARDS ATTRIBUTED TO ALERT LIFE SCIENCES COMPUTING2010Professional Merit Gold Medal Award, Gaia Municipality, Portugal

2007COTEC Innovation Award

1999 - to dateFounder & President, ALERT Life Sciences Computing, S.A.

1997 - 1999Post-doc in Gene Therapy, Genetics Department, Stanford University, U.S.A.

1993 - 1997Visiting Scientist, DNAX Research Institute, Palo Alto, U.S.A. Ph.D. in Medicine, Faculty of Medicine, University of Porto, Portugal

1991 - 1993Internship in Medicine, Hospital de S. João, Porto, Portugal

1985 - 1991Degree in Medicine, Faculty of Medicine, University of Porto,Portugal

2009Distinction in Professional Services, Rotary International

2008Medal of Honor from the Portuguese Business Association (AEP)

2008Ernst & Young Emerging Entrepreneur of the Year Award

2000Citizen of Merit of Viana do Castelo, Portugal

1998BIAL Grand Prize in Medicine

1997Medical Genetics Prize Jacinto Magalhães

MOST IMPORTANT PUBLICATIONS- Guimarães, M.J. Discovery of non-rigid eggs and hatchlings in two Archaeopteryx fossils. Paleo & Life, Abstracts of the 90th Annual Meeting of the Palaontologische Gesellschaft, Munich 2019, 53- Guimarães, M.J. The Rediscovery of Archaeopteryx (Vol. II): Archaeopteryx’s Hatchlings (ALERT Life Sciences Computing, Portugal, 2018). On sale at amazon.com- Guimarães, M.J. The Rediscovery of Archaeopteryx (Vol. I): Non-Rigid eggs in the Bird Lineage (ALERT Life Sciences Computing, Portugal, 2018). On sale at amazon.com- Guimarães, M.J. et al. Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in selenocysteine metabolism? Proc Natl Acad Sci U S A. 1996, 93: 15086-91- Guimarães, M.J. et al. Molecular cloning and characterization of lysosomal sialic acid O-acetylesterase. J Biol Chem. 1996, 271: 13697-705- Guimarães, M.J. et al. A new approach to the study of haematopoietic development in the yolk sac and embryoid bodies. Development. 1995, 121: 3335-46- Guimarães, M.J. et al. Differential display by PCR: novel findings and applications. Nucleic Acids Res. 1995, 23: 1832-3