magnesium
DESCRIPTION
TRANSCRIPT
Macromolecule: MagnesiumShould be provided in the foods that we eat every day
Third most abundant mineral in teeth
One of the major cations in plant & animal tissue
Essential ion (enzymatic reactions & protein synthesis)
Found mostly in bones and muscles, cell types and body fluids
Human body = 20 to 35 mg of Mg
Essential constituent of bone & soft tissues
Functions:Regulate body’s nerves &muscles
Plays a role in protein synthesis Activator of numerous coenzymes (carboxylase and co-A) Helps in catalyzing the transport of phosphate groups Binds mRNA Important in synthesis & degradation of DNA
Critical for normal metabolism& function of the organism
Absorption & Excretion1/3 is absorbed and utilized in the body
High intake of other macromolecule (Ca, P, lactose) will interfere with Mg absorption
Stored in bone---little excretion through the intestine
Mg is lost via urine & feces
Maintenance of the normal level of Mg in the blood depends on a balance between absorption and renal excretion of sodium.
Magnesium Deficiency
Conditions: Chronic malabsoprtion
syndrome
Acute diarrhea
Chronic renal failure
Chronic alcoholism
Symptoms: Hyperexcitability
Behavioral disturbances
Weakness
Depression
Tremors
Convulsions
Chronic Renal Failure:
Definition: Slow loss of kidney
function over time
Signs & Symptoms: Appetite loss
Nausea
Headache
Weight lossTreatment:
Controlling blood pressure will lower further kidney damage
Eat a healthy balanced diet
Chronic Alcoholism
Definition: Primary disease with
genetic, psychosocial, and environmental factors influencing its development and manifestations
Signs & Symptoms: Neglecting responsibilities due
to drinking
Tolerance (over time, one needs more and more alcohol to feel the same effects): 1st major warning sign of alcoholism
Withdrawal (body is used to alcohol and experiences withdrawal symptoms if it’s taken away): 2nd major warning sign of alcoholism Anxiety Depression Irritability and so on.
Acute Diarrhea
Definition: Abrupt onset of abnormally
high fluid content in the stool
Signs & Symptoms: Watery stool
Abdominal pain
Fever
dehydrationTreatment:
Fluid and electrolyte replacement
Dietary modifications
Drug therapy
Chronic malabsorption syndrome
Definition: Alteration in the ability of
the intestine to absorb nutrients adequately into the bloodstream
Signs & Symptoms: Diarrhea
Bloating
Flatulence
Weight loss
cramping
Treatment: Fluid and nutrient
replacement
Hypomagnesemia
Definition: Low levels of Magnesium in
the blood
Often leads to hypocalcemia (inhibition of parathyroid hormone; does not resolve until the magnesium deficiency has been corrected)
Signs & Symptoms: Muscle Weakness
Convulsions
Fatigue
Treatment: Food sources rich in
Magnesium should be obtained in the diet
Sources Mustard greens
Whole grains
Nuts
Soybeans
Green leafy veggies
Dietary allowance
Male: 350 mg
Females: 300 mg
Thank you and have a good day.