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ORIGINAL ARTICLE Magnetic resonance imaging evaluation of temporo-mandibular joint disorders, criterial analysis and significance in comparison with arthroscopy Reda Abdelsamie Alarabawy a, * , Hanan Mohamed El Ahwal a , Mervat Abd El Sattar El Sergany b , Wael Wagdy Mehrez c a Radiodiagnosis & Medical Imaging Department, Faculty of Medicine, Tanta University, Egypt b Physical Medicine, Rheumatology & Rehabilitation Department, Faculty of Medicine, Tanta University, Egypt c Radio-diagnosis & Medical Imaging Department, Kafr El Shekh General Hospital, Egypt Received 4 December 2015; accepted 1 January 2016 Available online 29 January 2016 KEYWORDS Temporo-mandibular joint; Magnetic resonance imaging; Arthroscopy Abstract Aim: The aim of our study was to analyze magnetic resonance imaging criteria in assess- ment of TMJ disorders and evaluate the important MRI role in comparison with arthroscopy. Patients and methods: The study was performed on eighty TMJs. TMJs are examined by 1.5 tesla MRI machine using sagittal oblique T1, PD & T2 weighted images & coronal oblique T1 and PD weighted images. The disk position, configuration, presence or absence of joint effusion, osteo-arthritis and mandibular condyle morphology were assessed. Comparison was done with arthroscopy in 49 joints. Results: Disk displacement was found in all cases symptomatic 80 joints, 60% bilateral and 40% unilateral. Joint pain and tenderness were the most clinical symptom followed by joint noise/ clicking. Thirty-five joints showed anterior disk displacement with reduction, while forty-five joints showed anterior disk displacement without reduction and one of them shows stuck disk in displaced position. MRI has sensitivity of 95, specificity of 88 and accuracy of 94 in comparison with arthro- scopy. Conclusion: MRI is proper diagnostic modality for TMJ disorders due to non invasiveness, excellent soft tissue contrast and multiplaner capabilities. Ó 2016 The Egyptian Society of Radiology and Nuclear Medicine. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc- nd/4.0/). Abbreviations: TMJ, temporo-mandibular joint; MRI, magnetic resonance imaging; ADDWR, anterior disk displacement with reduction; ADDWOR, anterior disk displacement without reduction * Corresponding author at: Radiodiagnosis Department, Tanta Faculty of Medicine, zefta, Gharbiya, Egypt. Mobile: +20 1009334485. E-mail address: [email protected] (R.A. Alarabawy). Peer review under responsibility of The Egyptian Society of Radiology and Nuclear Medicine. The Egyptian Journal of Radiology and Nuclear Medicine (2016) 47, 467–475 Egyptian Society of Radiology and Nuclear Medicine The Egyptian Journal of Radiology and Nuclear Medicine www.elsevier.com/locate/ejrnm www.sciencedirect.com http://dx.doi.org/10.1016/j.ejrnm.2016.01.002 0378-603X Ó 2016 The Egyptian Society of Radiology and Nuclear Medicine. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Page 1: Magnetic resonance imaging evaluation of temporo …ORIGINAL ARTICLE Magnetic resonance imaging evaluation of temporo-mandibular joint disorders, criterial analysis and significance

The Egyptian Journal of Radiology and Nuclear Medicine (2016) 47, 467–475

Egyptian Society of Radiology and Nuclear Medicine

The Egyptian Journal of Radiology andNuclearMedicine

www.elsevier.com/locate/ejrnmwww.sciencedirect.com

ORIGINAL ARTICLE

Magnetic resonance imaging evaluation of

temporo-mandibular joint disorders, criterial

analysis and significance in comparison with

arthroscopy

Abbreviations: TMJ, temporo-mandibular joint; MRI, magnetic resonance imaging; ADDWR, anterior disk displacement with re

ADDWOR, anterior disk displacement without reduction* Corresponding author at: Radiodiagnosis Department, Tanta Faculty of Medicine, zefta, Gharbiya, Egypt. Mobile: +20 1009334485.

E-mail address: [email protected] (R.A. Alarabawy).

Peer review under responsibility of The Egyptian Society of Radiology and Nuclear Medicine.

http://dx.doi.org/10.1016/j.ejrnm.2016.01.0020378-603X � 2016 The Egyptian Society of Radiology and Nuclear Medicine. Production and hosting by Elsevier B.V.This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Reda Abdelsamie Alarabawy a,*, Hanan Mohamed El Ahwal a,

Mervat Abd El Sattar El Serganyb, Wael Wagdy Mehrez

c

aRadiodiagnosis & Medical Imaging Department, Faculty of Medicine, Tanta University, EgyptbPhysical Medicine, Rheumatology & Rehabilitation Department, Faculty of Medicine, Tanta University, EgyptcRadio-diagnosis & Medical Imaging Department, Kafr El Shekh General Hospital, Egypt

Received 4 December 2015; accepted 1 January 2016Available online 29 January 2016

KEYWORDS

Temporo-mandibular joint;

Magnetic resonance imaging;

Arthroscopy

Abstract Aim: The aim of our study was to analyze magnetic resonance imaging criteria in assess-

ment of TMJ disorders and evaluate the important MRI role in comparison with arthroscopy.

Patients and methods: The study was performed on eighty TMJs. TMJs are examined by 1.5 tesla

MRI machine using sagittal oblique T1, PD & T2 weighted images & coronal oblique T1 and PD

weighted images. The disk position, configuration, presence or absence of joint effusion,

osteo-arthritis and mandibular condyle morphology were assessed. Comparison was done with

arthroscopy in 49 joints.

Results: Disk displacement was found in all cases symptomatic 80 joints, 60% bilateral and 40%

unilateral. Joint pain and tenderness were the most clinical symptom followed by joint noise/

clicking. Thirty-five joints showed anterior disk displacement with reduction, while forty-five joints

showed anterior disk displacement without reduction and one of them shows stuck disk in displaced

position. MRI has sensitivity of 95, specificity of 88 and accuracy of 94 in comparison with arthro-

scopy.

Conclusion: MRI is proper diagnostic modality for TMJ disorders due to non invasiveness,

excellent soft tissue contrast and multiplaner capabilities.� 2016 The Egyptian Society of Radiology andNuclearMedicine. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-

nd/4.0/).

duction;

Page 2: Magnetic resonance imaging evaluation of temporo …ORIGINAL ARTICLE Magnetic resonance imaging evaluation of temporo-mandibular joint disorders, criterial analysis and significance

468 R.A. Alarabawy et al.

1. Introduction

Temporo-mandibular joint (TMJ) pain and dysfunction arecommonly seen important clinical problems and according to

some studies, affect up to 28% of population (1).The most frequent cause of TMJ dysfunction, or TMJ dis-

order, is internal derangement, which is defined as an abnor-

mal relationship of the disk to the condyle. MR imaginghelps in assessment of signs of TMJ dysfunction. Since theadvent of MR imaging there have been substantial improve-

ments in both hardware and software that currently allow bet-ter visualization of small structures such as retrodiscal layersor lateral pterygoid muscle attachment (1).

Magnetic resonance imaging is accepted as the most

advanced imaging modality for diagnosis of TMJ abnormali-ties. It is non invasive and has the potential to yield high qual-ity tomographic imaging in any plane with bone as well as soft

tissue spatial resolution. Additionally, the patient was notexposed to ionizing radiation or any biological hazards. Otheradvantages of MR imaging are its sensitivity, specificity and

diagnostic accuracy (2).

Fig. 1 Sagittal oblique (A) closed- and (B) open-mouth show right T

Fig. 2 Sagittal oblique (A) closed- and (B) open-mouth show right TM

and deformed disk.

MR imaging represents the best method for studying clini-cally affected joints, for the evaluation morphological status ofTMJ and for the analysis of dynamic process during mouth

opening (3). This is not true dynamic images but it is pseudodynamic MR imaging obtained from the serial multiple staticimages (4).

MR imaging is the best technique to correlate and compareTMJ components such as bone, disk, fluid, capsule and liga-ments with autopsy specimens (5).

Our issue is to analyze magnetic resonance imaging criteriain assessment of TMJ disorders especially internal diskderangement and evaluate the important MRI role in compar-ison with arthroscopy (see Figs. 1–6).

2. Patients and methods

In this retrospective study, we included 50 consecutive patients(80 joints) who were referred from dentist’s and rheumatolo-gist’s clinics. They were suffering from clinical manifestationsof temporo-mandibular joint affection.

MJ anterior disk displacement with reduction and joint effusion.

J anterior disk displacement without reduction with joint effusion

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Fig. 3 Sagittal oblique (A) closed- and (B) open-mouth show right TMJ anterior disk displacement without reduction with deformed

disk and joint effusion.

Fig. 4 Sagittal oblique (A) closed- and (B) open-mouth show right TMJ stuck disk (adhesive disk). The disk is seen fixed in a displaced

position with no mobility of the condyle.

Magnetic resonance imaging criteria in assessment of TMJ disorders 469

This study was performed at the period from April 2013 to

October 2015.

The clinical inclusion criteria for the study group wereassessed on following clinical characteristics:

1. Limited mouth opening or crepitation.2. Deflection of mandible or pain at mouth opening.

The exclusion criteria for the study group were as follows:

1. Patient with systemic disease affects TMJ as rheuma-toid arthritis.

2. Patient with obvious skeletal jaw deformity or previoustrauma.

3. Contra-indication to MRI as claustrophobic and

uncooperative patients, or who had cerebral aneurysmclip and cardiac pace maker.

Metallic prosthesis like heart valves and ferromagnetic for-eign bodies in critical location like eye.

This study was conducted according to the guidelines of the

ethics committee of our university and was approved by ourinstitutional review board. All patients gave written informed

consent to be imaged in our study.All the patients were subjected to the following:

1. Detailed history with special emphasis on: history ofthe present illness rheumatoid arthritis and traumaprevious interference.

2. Clinical examination including palpation of the TMJand

muscles ofmastication forpain, palpationof joint sounds,stability as well asmeasurement of the range ofmotion.

3. Laboratory investigations: such as complete blood pic-

ture, rheumatoid factor and ESR.4. Diagnostic examination and imaging:

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Fig. 5 Right TMJ sagittal oblique (A) closed- and (B) open-mouth show right TMJ anterior disk displacement without reduction with

deformed disk. Left TMJ sagittal oblique (C) closed- and (D) open-mouth show Left TMJ anterior disk displacement with reduction.

470 R.A. Alarabawy et al.

Conventional MR study:

1. The MRI machine: MRI scans were performed using(General Electric SIGNA) HS (high speed) 1.5 T system

in MRI unit of Radiodiagnosis and Medical Imaging

Department at Tanta University Hospital.2. Technique Patient was laid supine with both arms

adducted where the special TMJ dual coil was appliedfor the examination.

Imaging started by axial localizer including the whole skullbase.

Pulse sequences spine echoes were obtained from allpatients in closed and maximal open mouth positions on cor-rected (oblique) sagittal T1 weighted; proton density (PD) and

T2 weighted images with corrected (oblique) coronal viewsdone in T1 and PD weighted images.

Matrix: 256 � 128, field of view: 10–12 cm. Number

of slices: 18, Slice thickness/space: 3 mm, Imaging time:3.14 min.

TMJ Localizer: plane: Axial, Pulse sequence: Spin-echo,Number of slices: 10, Slice thickness/space: 5/2 mm, TR/

TE:300 ms/12 ms. Imaging time: 28 s.

Sagittal and coronal oblique T1 weighted image – Repetition

time: 400–500 ms, Echo time: 10–20 s.

Sagittal and coronal oblique PD weighted image – Repetition

time: 2000 ms, Echo time: 10–14 ms.Sagittal oblique T2 weighted image: – Repetition time:

2600 ms, Echo time: 120 ms.True FISP sequence. It uses ultrashort TR allowing higher

spatial resolution (by decreasing the FOV) or higher temporalresolution (by reducing the FOV and raw data matrix size).

3D fast spoiled gradient echo recalled sequence (3D FSPGR).Best depiction of cortical bone thinning, erosions, surface irreg-ularities and subcortical bone cysts.

Dynamic images are obtained as rapid acquisition of staticimages using a single shot fast spin echo (SSFSE) T2 weightedimage (as SSFSE proton density sequence not routinely used in

our machine) during progressive opening and closing of themouth. These images are displayed sequentially as a cine loop.Mouth opening devices such as Burnett opening devices may

be used or anything like empty syringe put in mouth to keepit opened. Oblique imaging entails 30� medial from the truesagittal plane. Eight sequences are performed. Dynamic imag-ing is performed in straight sagittal orientation along the antic-

ipated path of condylar motion.

Page 5: Magnetic resonance imaging evaluation of temporo …ORIGINAL ARTICLE Magnetic resonance imaging evaluation of temporo-mandibular joint disorders, criterial analysis and significance

Fig. 6 Right TMJ sagittal oblique (A) closed- and (B) open-mouth show right TMJ anterior disk displacement without reduction with

joint effusion, deformed disk and mandibular osteoarthritic changes (flattening and cortical irregularity). Left TMJ sagittal oblique (C)

closed- and (D) open-mouth show left TMJ anterior disk displacement without reduction with joint effusion, deformed disk and

mandibular osteoarthritic changes (flattening, cortical irregularity and anterior osteophytosis).

Magnetic resonance imaging criteria in assessment of TMJ disorders 471

Intravenous contrast is not routinely done in our study, as itis used in suspicion of severe inflammatory arthritis orneoplasm.

Images interpretation was done by two consultant radiolo-

gists with experience of fifteen years and six years.Arthroscopy was done in 40 cases (49 joints) after MRI in

patients with relatively advanced complaint that agrees to do

arthroscopy according to surgical decision.Both TMJs were examined for disk position, disk configu-

ration, presence or absence of joint effusion in TMJ space

and morphology of mandibular condyle.

3. Statistical analysis

Statistical presentation and analysis of the present study wasconducted, using the P value and chi-square test by SPSS V.20.

Statistical analysis was undertaken to prove the efficacy ofMRI in diagnosis of internal derangement of TMJ as it is con-

sidered the most important and most prevalent pathology ofTMJ and its grade, either reducible or not.

Sensitivity, specificity and accuracy of MRI findings in

comparison with arthroscopy were calculated.

4. Results

In this study, 50 patients were included suffering from clinicalmanifestations of temporo-mandibular joint (TMJ) affections.

– Age and sex distribution of examined patients dis-cussed in (Table 1).

– Clinical manifestations of the examined patients

(Table 2 and Diagram 1).– Of these 50 patients there were 30 patients suffering

from bilateral complaints representing 60% of casesand 20 patients had unilateral affection representing

40%, 14 of them were right sided while 6 were left.

The final results of the TMJs of the patients examined by

conventional MRI were categorized as shown in Table 3 into:

Grade I Anterior disk displacement with reduction

(ADDWR):

In the closed mouth position, the posterior band of the diskis anterior to the condylar head in all the sagittal sections.When the jaw is opened, the disk is recaptured by the condyle

and the disk condyle relation appears as normal.

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Table 1 Age and sex distribution of the examined patients.

Age group Number Percentage (%)

Patients age

14–20 years 25 50

21–30 years 18 36

31–49 years 7 14

Total 50 100

Patients sex

Females 33 66

Male 17 34

Total 50 100

Table 2 Distribution of patients according to clinical

presentations.

Clinical presentation Patients number Percentage (%)

Joint pain and tenderness 36 72

Joint noise/clicking 32 64

Deflection/deviation 22 44

Limited mouth opening 21 42

Muscle tenderness 19 38

38%42%44%

64%72%

01020304050607080

Joint painand

tenderness

Joint noise/clicking

Deflection/deviation

Limitedmouth

opening

Muscletenderness

%

Diagram 1 Distribution of patients according to clinical

presentations.

Table 3 Distribution of patients according to MRI grading of

TMJs disk displacement.

Type of disk displacement

Grade I Grade II

Reducibility Reducible Non-reducible

Number of joints 35 (44%) 45 (56%)

X2 6.250

P-value 0.012*

A-Grade I anterior disk displacement with reduction (ADDWR).

B-Grade II Anterior disk displacement without reduction

(ADDWOR).* Significant.

Table 4 Pattern of disk shape and disk signal.

Type of disk

displacement

X2 P-value

Grade I Grade II

Pattern of disk shape

Normal disk shape 29 (83%) 17 (38%) 16.372 <0.001*

Deformed disk shape 6 (17%) 28 (62%)

Pattern of disk signal

Normal disk signal 29 (83%) 25 (56%) 6.689 0.010*

Deformed disk shape 6 (17%) 20 (44%)

* Significant.

Table 5 Temporo-mandibular joint effusion & osteo-arthritic

changes.

Type of disk displacement X2 P-value

Grade I Grade II

Joint effusion

Present 3 (9%) 11 (24%) 3.436 0.064

Absent 32 (91%) 34 (76%)

Secondary osteo-arthritic changes

Positive 0 (0.0%) 11 (24%) 9.919 0.002*

Negative 35 (100%) 34 (76%)

* Significant.

472 R.A. Alarabawy et al.

There were 35 joints (35%) showing grade I internalderangement. They were 19 patients (16 were bilateral and 3

were unilateral).

Of these 35 joints, 29 joints showed normal shaped disk andonly 6 joints showed deformed disks with altered signalintensity.

Three joints showed associated effusion. No joints showedsecondary degenerative osteo-arthritic changes.

(X2 4.362 P value 0.003*)

Grade II Anterior disk displacement without reduction

(ADDWOR): In close and open mouth position, the posteriorband of the disk is anterior to the superior aspect of the condy-lar head in all sagittal section. When the jaw is opened, the diskis anteriorly compressed, whether its shape is modified or not.

There were 45 joints showing grade II internal derange-ment. They were 31 patients (17 were unilateral and 14 werebilateral). Of these 45 joints, 17 joints showed normal shaped

disk and 28 joints showed deformed disks. Also 20 of themshow altered signal while 25 of them show normal signal. 11joints showed associated effusion and secondary degenerative

osteo-arthritic changes.

(X2 5.257 P value 0.009*)

– Pattern of disk deformity and disk signal displayed inTable 4.

– Temporo-mandibular joint effusion & osteo-arthritis shownin Table 5.

Comparison study between MRI and arthroscopy for evalua-

tion of temporo-mandibular joint internal derangement was done

on selected 40 patients (of 49 TMJs, 31 unilaterally and 9 bilat-erally affected) showing that MRI detects anteriorly displaceddisks in 41 joints out of 49 joints representing 83.7%, while 8

TMJs (16.3%) showed normal disk position.

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Table 6 Diagnostic accuracy of MRI in assessment of TMJs

disk displacement in comparison with arthroscopy findings.

Total 49 joints (Abnormal findings) disk displacement

True +ve False +ve True �ve False �ve

Number 39 2 7 1

% 79.59 4.08 14.29 2.04

X2 0.677

P-value 0.411

Sensitivity Specificity Accuracy

95 88 94

84

86

88

90

92

94

96

%

Sensitivity Specificity Accuracy

Diagram 2 Diagnostic accuracy of MRI in assessment of TMJs

disk displacement in comparison with arthroscopy findings.

Magnetic resonance imaging criteria in assessment of TMJ disorders 473

MRI revealed 14 TMJs (28.6%) with anterior disk displace-ment with reduction (ADDWR), while 27 TMJs (55.1%) withanterior disk displacement without reduction (ADDWOR).

Arthroscopy revealed 39 cases are true positive TMJs out of

49 joints (79.6%) with anteriorly displaced disks. Two casesare false positive (4.1). 7 TMJs (14.3%) are true negative. whileone joint was false negative (2%).

Arthroscopy revealed 13 TMJs (26.5%) with anterior diskdisplacement with reduction (ADDWR), while 26 TMJs(53.1%) show anterior disk displacement without reduction

(ADDWOR).Sensitivity 95, specificity 88 and accuracy 94 with positive

predictive value (PPV = 95%) and negative predictive value

(NPV = 87.5%) (Table 6 and Diagram 2).

5. Discussion

Major components of the TMJ include the mandibular con-dyle, the articular disk, the glenoid fossa, and the articular emi-nence of the temporal bone. Unlike most joints, thearticulating surfaces are fibrous and not cartilaginous. The

fibrocartilaginous articular disk is biconcave, dividing the jointspace into superior and inferior compartments. With the rapidprogress made in TMJ imaging techniques, many studies have

focused on the importance of internal derangement,osteoarthrosis (OA), effusion, and bone marrow edema(BME) as the underlying mechanisms in the etiology of TMJ

disorders (6).

MRI with the use of surface coils has markedly improvedthe delineation of internal derangement of the TMJ and hasexpanded the knowledge of the anatomical details of such joint

enhancing the capabilities of the diagnosis of certain patholog-ical processes involving this joint. (7).

In the present work, sex showed statistically significant dif-

ferences between the studied groups. Out of total 50 patientsstudied, 33 were females and 17 were males. The ratio offemale to male in this group of patients with temporomandibu-

lar joint disorders was 1.9:1. Higher female ration in this studyis in agreement with that of Amin et al., (8) who foundincreased ratio of female to male patients with temporo-mandibular joint dysfunctions (2.5:1). Other study by Okeson

(9) reported with comparable results.Another study done by Dalkiz et al. (10) showing that pain

and dysfunction TMJ disorders seem to affect women more

than men with clinical reports has emphasized the high ratio(8.67:1) of female to male patients for TMJ disorders.

The factors responsible for this predominance are not

known however. It has been suggested in animal studies thatjoint laxity involving any joint occurs more commonly infemales than in males. It is suggested that individuals with

joint laxity as a result of altered collagen synthesis are atgreater risk of developing bilateral temporomandibular jointdysfunction (TMD) when subjected to etiological factors suchas trauma, joint overextension, or joint over-use (11).

The current work included 50 patients with symptoms andsigns of TMJ dysfunction as follows: joint pain and tenderness,joint noise and clicking sensation, limited jaw opening and

muscle tenderness.In the present study, the most common clinical symptom/

sign of the examined patients group was pain/tenderness in

preauricular region (36 out of 50 patients) representing 72%with regard to the patients who suffer TMJ pain, and numer-ous studies based on examination of the MR findings have

been carried out. The main findings that are responsible forthe etiology are disk malposition, effusion and osteoarthrosis(12). This is in agreement with those of Okeson (9) whoreported that disk displacement of TMJ is the important cause

of facial and TMJ pain.On the contrary, Adame et al. (13) in his study stated that

the cause of pain/tenderness could be associated with retrodis-

cal tissue alteration, capsulitis, synovitis. This is in agreementwith a study done by Farina et al. (14) showing that MR signalchanges in retrodiscal tissue are highly correlated with TMJ

pain.In the present study, joint noise was found in 32 out of 50

patients (64%), thus indicating that TMJ clicking might occuras a consequence of frictional incompatibility between disk

and the eminence, when the posterior band of the disk movesanteriorly or posteriorly beyond the apex of the articular emi-nence. Other causes may be deviation in condylar form

(remodeling), adhesion or muscular incardination. Our expla-nation goes with the study done by Imanimoghaddam et al.(15) who concluded that strong correlation exists between disk

displacement on MRI and TMJ click.The diagnosis of medullary bone signs is influenced by the

type of parameter used for MRI. T2 WI is best while any of the

parameter such as T1W, T2W, or PDW was used to evaluatedisk morphology and function (16) and this goes with ourMRI sequences in this search.

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474 R.A. Alarabawy et al.

In our study, bilateral affection of the temporomandibularjoints was noted in 60% of the examined patients. In the studydone by Romanelli et al. (17), bilateral temporomandibular

joints affection was noted in 63% of cases examined withMRI. It is suggested that the incidence of bilateral internalderangement in patients may be in the range of 50–60%.

The reason for the high incidence of bilateral involvement ofthe TMJs is unknown. However, it may be hypothesized thatpatients who have a prior history of injury or trauma to the

head, neck or jaws may have sustained either direct or indirectdamage to the TMJ. Therefore, any exogenous factor that mayparticipate in the development of internal derangement in onetemporo-mandibular joint may lead to development of internal

derangement in the contra-lateral joint. While symptoms maybe present in both joints, the patient may experience pain anddysfunction of greater intensity and severity on the other side

(17).In the present study the incidence of disk displacement was

reported in all cases representing 100% compared to 86% in

the study done by Emshoff et al. (6). This disagrees with astudy done by Samara et al. (18) reveled that 30% of the stud-ied cases shows no abnormalities on MRI examination.

In a study done by Amin et al. (8) on 28 joints examined byMRI, 8 joints showed disk displacement with reduction(28.7%), while 16 joints showed disk displacement withoutreduction (57.1%). This agrees with our study, as there were

35 joints showing anterior disk displacement with reductionrepresenting 44% of cases and there were 45 joints showedanterior displacement without reduction representing 56% of

examined joints.In a study done by Yilmaz & Toller (19) evaluating 133

temporomandibular joints by MRI, they found that the artic-

ular disk is deformed in 52.38% of the joints with reducedanteriorly displaced disk whereas 85.71% of the non reducibledisks were deformed. In the present study, the deformed disks

represent 83% of the anteriorly displaced non reducible. In theanteriorly displaced reducible disks, disk deformities repre-sented 17% all agree to fact the close association between per-manent disk displacement (without reduction) and bone

changes is well documented (20).In our study bony osteoarthritic changes were diagnosed in

11 joints out of 45 joints showing anteriorly displaced disk

without reduction representing 24%. This is in agreement withthose of Milano et al. (20), and they found bony changes in 15joints out of the 43 joints with non reducible anterior disk dis-

placement. Also, these results agreed with those of Emshoffet al. (6), and they found a significant relationship betweengrade II TMJ internal derangement and osteoarthritis andbone marrow edema as well as a significant increase in risk

of pain.Sano et al. (21) reported that degree of pain in TMJs with

bone marrow abnormalities was significantly higher than in

TMJs with normal bone marrow signal on MR images whichsupports the concept that bone marrow abnormalities repre-sent a response to an increased intra-articular pressure in con-

ditions of pronounced inflammatory process such as synovitis.In the present study, joint effusion was diagnosed only in 11

joints of the anteriorly displaced disks without reduction with

secondary bony changes representing 24% of the joints withgrade II disk degeneration (45 joints). Also we diagnosed threejoints in anteriorly displaced disk with reduction showing effu-

sion. Thus, we diagnosed 14 joints with effusion out of theexamined joints showing internal derangement.

This is in agreement with a study done by Emshoff et al. (6)

who reported joint effusion in 8 of 16 temporomandibularjoints with anterior disk displacement. These results alsoagreed with those of Orlando et al. (22) who found that there

is a significant correlation between disk displacement and jointeffusion and that a non reducible disk represents a risk factorfor the occurrence of joint edema more than a reducible one.

In present study, one joint showed stuck disk in anteriorlydisplaced position. This agrees with that of Amin et al. (8), andthey found that stuck disk represents 3 joints of studied group.

Milano et al. (20) found that sideway disk displacement is

rare (1.5%) in their study, and we did not diagnose lateral ormedial disk displacement in our study. One possible explana-tion for the rarity sideway disk displacement compared to

anterior disk displacement is that the anterior direction is theline of least resistance for disk movements whereas the medialand lateral surfaces are more firmly supported by their

ligaments while posterior disk displacement is much less likelyto occur as the normal position of the disk is anterior to thecondyle (23).

Comparison study between MRI and arthroscopy forevaluation of temporo-mandibular joint internal derangementwas done on selected 40 patients (of 49 TMJs, 31 unilaterallyand 9 bilaterally affected) showing that MRI detects anteriorly

displaced disks in 41 joints out of 49 joints representing 83.7%,while 8 TMJs (16.3%) showed normal disk position.

MRI revealed 14 TMJs (28.6%) with anterior disk displace-

ment with reduction (ADDWR), while 27 TMJs (55.1%) withanterior disk displacement without reduction (ADDWOR).

Arthroscopy revealed 39 cases are true positive TMJs out of

49 joints (79.6%) with anteriorly displaced disks. Two casesare false positive (4.1). 7 TMJs (14.3%) are true negative, whileone joint was false negative (2%).

Arthroscopy revealed 13 TMJs (26.5%) with anterior diskdisplacement with reduction (ADDWR), while 26 TMJs(53.1%) show anterior disk displacement without reduction(ADDWOR). This is in agreement with a study done by Amin

et al. (8) which showed that MRI examination revealed 24joints out of 28 joints with anteriorly displaced disks represent-ing 85.7%, while arthroscopy revealed 20 joints out of 28 joints

with anteriorly displaced disks representing 71.4%. It is notedthat both MRI and arthroscopy are statistically correlatedwith each other in detecting TMJ internal derangement, with

sensitivity 95, specificity 88 and accuracy 94 with positivepredictive value (PPV = 95%) and negative predictive value(NPV= 87.5%) but reviewing the results highlighted theadvantages of preoperative MRI as a non invasive highly

yielded diagnostic modality in comparison with arthroscopyin diagnosing disk position.

Our results do not go with Zhang et al. (24) who concluded

that the diagnostic accuracy of MRI for intra-articular adhe-sions was poor; most of the adhesions were not diagnosed byMRI, but intracapsular adhesions could be detected on T2

weighted-images with existing synovial fluid.On the contrary our study results agree with Shen et al. (25)

who concluded that MRI proved to be a good modality to

diagnose disk perforation of TMJ, and the diagnostic resultof disk perforation by MRI had certain guiding significancein our clinical work.

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Magnetic resonance imaging criteria in assessment of TMJ disorders 475

Different imaging modalities, each with inherent strengthand weakness were used to image TMJ. MRI is diagnostictechnique of choice due to its superior contrast resolution

and its ability to acquire dynamic imaging to demonstrate itsfunction (26).

6. Conclusion

Disk displacement or internal disk derangement is the mostprevalent disorder. There is a statistically significant associa-

tion between anterior disk displacement without reductionand deformed disk configuration, joint effusion and secondaryosteoarthritic changes.

MRI is a proper diagnostic modality for TMJ disorders incomparison with arthroscopy due to non invasiveness, theexcellent soft tissue contrast and multi-planer capabilities.

Conflict of interest

The authors declare that there are no conflict of interest.

References

(1) Tomas X, Pomes J, Berenguer J. MRI imaging of temporo-

mandibular joint dysfunction: a pictorial review. Radiographics

2006;26(3):765–81.

(2) Michelle A, Wessely F, Martin Y. Magnetic resonance imaging of

the temporomandibular joint. Clin Chiropractic 2008;11:37–44.

(3) Mark S, Bodo K, Christina L. Temporomandibular joint disc

position assessed at coronal MR imaging in asymptomatic

volunteers. Radiology 2005;236:559–64.

(4) Jin-HO L, Kyoung-In Y, In-Woo P. Comparison of static

MRI and Pseudo-dynamic MRI in temporomandibular joint

disorder patients. Korean J Oral Maxillofacial Radiol 2006

(36):199–206.

(5) Rudisch A, Emshoff R, Maurer H, et al. Pathologic sonographic

correlation in temporomandibular joint pathology. Eur Radiol

2006;16:1750–6.

(6) Emshoff R, Gerhard S, Ennemoser T, Rudisch A. Magnetic

resonance imaging findings of internal derangement, osteoarthro-

sis, effusion, and bone marrow edema before and after perfor-

mance of arthrocentesis and hydraulic distension of the

temporomandibular joint. Oral Surg Oral Med Oral Pathol Oral

Radiol Endod 2006;101:784–90.

(7) El-Essawy M, Al-Nakshabandi N, Al-Boukai A. Magnetic

resonance imaging evaluation of tempromandibular joint

derangement in symptomatic and asymptomatic patients. Saudi

Med J 2008;29(10):1448–52.

(8) Amin M, Hassan A, Barakat K. The accuracy of dynamic

magnetic resonance imaging in evaluation of internal derange-

ment of the temporomandibular joint; comparison with arthro-

scopic findings. Egyptian J Radiol Nucl Med 2012;43:429–36.

(9) Okeson JP. Diagnosis of temporomandibular disorders in man-

agement of temporomandibular disorders and occlusion. St

Louis, Missouri: Mosby; 2008, p. 285.

(10) Dalkiz M, Pakdemirli E, Beydemir B. Evaluation of TMJ

dysfunction by magnetic resonance imaging. Turk J Med Sci

2001;31:337–43.

(11) Nebbe B, Major PW. Prevalence of TMH displacement in a pre-

orthodontic adolescent sample. Angle Orthodontist 2000;70(6).

(12) Chiba M, Kumagai M, Echigo S. Association between high signal

intensity in the posterior disc attachment seen on T2 weighted fat

suppressed image and temporo-mandibular joint pain. Dento-

Maxillo Face Radiol 2007;36(4):187–91.

(13) Adame CG, Monje F, Offnoz M, Mrtin-Granizo R. Effusion in

magnetic resonance imaging of the temporomandibular joint: a

study of 123 joints. J Oral Maxillofac Surg 1998;56:314–8.

(14) Farina D, Bodin C, Gandolfi S, et al. TMJ disorders and pain:

assessment by contrast-enhancedMRI. Eur J Radiol 2009;70:25–30.

(15) ImanimoghaddamM, Madani AS, Mahmooudi Hashemi E. MRI

findings in patients with TMJ click. J Dent Mater Tech 2014;3

(1):28–36.

(16) Alonso MBCC, Gamba TO, Lopes, et al. Magnetic resonance

imaging of the temporo-mandibular joint acquired using different

parameters. J Morphol Sci 2014;31(2):103–9.

(17) Romanelli GG, Harper R, Mock d, et al. Evaluation of temporo-

mandibular joint internal derangement. J Orofac Pain 1993;7

(3):254–62.

(18) Samara O, Hadidy A, Haroun D, et al. Correlation between

clinical and magnetic resonance imaging (MRI) findings in

temporomandibular disorders. J Clin Med Res 2012;4(9):109–13.

(19) Yilmaz NT, Toller MO. Magnetic resonance imaging evaluation

of temporomandibular joint disc deformities in relation to type of

disc displacement. J Oral Maxillofac Surg 2001;59:860–5.

(20) Milano V, Desiate A, Bellino R, et al. Magnetic resonance

imaging of temporomandibular joint disorders: classification,

prevalence and interpretation of disc displacement and deforma-

tion. Dent Maxillofac Rad 2000;29:352–61.

(21) Sano T, Westesson PL, Larheim TA, Takagi R. The association

of temporo-mandibular joint pain with abnormal bone marrow in

the mandibular condyle. J Oral Maxillofac Surg 2000;58:254–7.

(22) Orlando B, Chiappe G, Landi N, Bosco M. Risk of TMJ effusion

related to magnetic resonance imaging signs of disc displacement.

Med Oral Pathol Oral Cir Bucal 2009;14(4):188–93.

(23) Katzberg RW, Westesson PL, Tallents HR, et al. Orthodontics

and temporomandibular joint internal derangement. Am J

Orthodont Dentofac Orthoped 1996;109:505–20.

(24) Zhang S, Yang C, Chen M, Fan X, Yun B, Peng Y, et al.

Magnetic resonance imaging in the diagnosis of intra-articular

adhesions of the temporomandibular joint. Br J Oral Maxillofac

Surg 2009;47(5):389–92.

(25) Shen P, Huo L, Zhang SY, Yang C, Cai XY, Liu XM. Magnetic

resonance imaging applied to the diagnosis of perforation of the

temporomandibular joint. J Craniomaxillofac Surg 2014;42

(6):874–8.

(26) Bag Asim K, Gaddikeri Santhosh, Joel K. Imaging of the

temporo-mandibular joint. Word J Radiol 2014:1–281.