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Magnetic Resonance Imaging Group Journal papers Published: E.Y. Kim, D.-H. Kim, E. Yoo, H.-J. Park, X. Golay, S.-K. Lee, D.J. Kim, J. Kim, D.I. Kim, “Visualization of maturation of the corpus callosum during childhood and adolescence using T2 relaxometry”, Int J Dev Neuroscience, 25(6), 409-414 2007. X. Golay, E.T. Petersen, I. Zimine and T.C.C. Lim, “Arterial Spin Labeling: a One-stop-shop for Measurement of Brain Perfusion in the Clinical Settings”, Proc. 29 th IEEE EMBS, 4320-4323. 2007. J. Hendrikse, E.T. Petersen, P.J. Van Laar, X. Golay, “Cerebral Border Zones between Distal End Branches of Intracranial Arteries: MR Imaging”, Radiology, 246(2), 572-580, 2008. Wu CW, Chuang KH, Wai YY, Wan YL, Chen JH, Liu HL. “Vascular space occupancy-dependent functional MRI by tissue suppression.” J Magn Reson Imaging. 28(1):219-26. 2008. Chng SM, Petersen ET, Zimine I, Sitoh YY, Lim CC, Golay X. “Territorial arterial spin labeling in the assessment of collateral circulation: comparison with digital subtraction angiography.” Stroke. 39(12):3248-54. 2008. Ho YC, Vidyasagar R, Shen Y, Balanos GM, Golay X, Kauppinen RA. “The BOLD response and vascular reactivity during visual stimulation in the presence of hypoxic hypoxia.” Neuroimage. 41(2):179-88. 2008. Waghorn B, Edwards T, Yang Y, Chuang KH, Yanasak N, Hu TC. “Monitoring dynamic alterations in calcium homeostasis by T (1)-weighted and T (1)-mapping cardiac manganese-enhanced MRI in a murine myocardial infarction model.” NMR Biomed. 21(10):1102-11. 2008. Yang P, Wang PN, Chuang KH, Jong YJ, Chao TC, Wu MT. “Absence of gender effect on children with attention-deficit/hyperactivity disorder as assessed by optimized voxel-based morphometry.” Psychiatry Res. 164(3):245-53. 2008. Shen Y, Kauppinen RA, Vidyasagar R, Golay X. “A functional magnetic resonance imaging technique based on nulling extravascular gray matter signal.” J Cereb Blood Flow Metab. 29(1):144-56. 2009. Smith SA, Golay X, Fatemi A, Mahmood A, Raymond GV, Moser HW, van Zijl PC, Stanisz GJ. “Quantitative magnetization transfer characteristics of the human cervical spinal cord in vivo: application to adrenomyeloneuropathy.” Magn Reson Med. 61(1):22-7. 2009. Submitted: J. Laothamatas, C. Tosti, X. Golay, M. Van Cauteren, V. Lekprasert, N. Tangpukdee, S. Krudsood, W. Leowattana, P. Wilairatana, S. Swaminathan, R.L. DeLaPaz, T.R. Brown, S. Looareesuwan, G.M. Brittenham, “Transient ischemic lesion in the splenium of the corpus callosum in patients with acute uncomplicated falciparum malaria” TCC Hu, KH Chuang, N Yanasak, AP Koretsky. “Relation between Blood and Cardiac Manganese during Manganese Enhanced Magnetic Resonance Imaging (MEMRI) with T1 Mapping in the Rodent.” (submitted to NMR Biomed) V.K. Shinoj, V.M. Murukeshan, S. Padmanabhan, P. Padmanabhan. “An integrated dual modality probe using double clad photonic crystal fiber and micro CCD camera for sensing and imaging application.” (submitted to Applied Optics) 1 of 26

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Magnetic Resonance Imaging Group Journal papers Published:

• E.Y. Kim, D.-H. Kim, E. Yoo, H.-J. Park, X. Golay, S.-K. Lee, D.J. Kim, J. Kim, D.I. Kim, “Visualization of maturation of the corpus callosum during childhood and adolescence using T2 relaxometry”, Int J Dev Neuroscience, 25(6), 409-414 2007.

• X. Golay, E.T. Petersen, I. Zimine and T.C.C. Lim, “Arterial Spin Labeling: a One-stop-shop for Measurement of Brain Perfusion in the Clinical Settings”, Proc. 29th IEEE EMBS, 4320-4323. 2007.

• J. Hendrikse, E.T. Petersen, P.J. Van Laar, X. Golay, “Cerebral Border Zones between Distal End Branches of Intracranial Arteries: MR Imaging”, Radiology, 246(2), 572-580, 2008.

• Wu CW, Chuang KH, Wai YY, Wan YL, Chen JH, Liu HL. “Vascular space occupancy-dependent functional MRI by tissue suppression.” J Magn Reson Imaging. 28(1):219-26. 2008.

• Chng SM, Petersen ET, Zimine I, Sitoh YY, Lim CC, Golay X. “Territorial arterial spin labeling in the assessment of collateral circulation: comparison with digital subtraction angiography.” Stroke. 39(12):3248-54. 2008.

• Ho YC, Vidyasagar R, Shen Y, Balanos GM, Golay X, Kauppinen RA. “The BOLD response and vascular reactivity during visual stimulation in the presence of hypoxic hypoxia.” Neuroimage. 41(2):179-88. 2008.

• Waghorn B, Edwards T, Yang Y, Chuang KH, Yanasak N, Hu TC. “Monitoring dynamic alterations in calcium homeostasis by T (1)-weighted and T (1)-mapping cardiac manganese-enhanced MRI in a murine myocardial infarction model.” NMR Biomed. 21(10):1102-11. 2008.

• Yang P, Wang PN, Chuang KH, Jong YJ, Chao TC, Wu MT. “Absence of gender effect on children with attention-deficit/hyperactivity disorder as assessed by optimized voxel-based morphometry.” Psychiatry Res. 164(3):245-53. 2008.

• Shen Y, Kauppinen RA, Vidyasagar R, Golay X. “A functional magnetic resonance imaging technique based on nulling extravascular gray matter signal.” J Cereb Blood Flow Metab. 29(1):144-56. 2009.

• Smith SA, Golay X, Fatemi A, Mahmood A, Raymond GV, Moser HW, van Zijl PC, Stanisz GJ. “Quantitative magnetization transfer characteristics of the human cervical spinal cord in vivo: application to adrenomyeloneuropathy.” Magn Reson Med. 61(1):22-7. 2009.

Submitted:

• J. Laothamatas, C. Tosti, X. Golay, M. Van Cauteren, V. Lekprasert, N. Tangpukdee, S. Krudsood, W. Leowattana, P. Wilairatana, S. Swaminathan, R.L. DeLaPaz, T.R. Brown, S. Looareesuwan, G.M. Brittenham, “Transient ischemic lesion in the splenium of the corpus callosum in patients with acute uncomplicated falciparum malaria”

• TCC Hu, KH Chuang, N Yanasak, AP Koretsky. “Relation between Blood and Cardiac Manganese during Manganese Enhanced Magnetic Resonance Imaging (MEMRI) with T1 Mapping in the Rodent.” (submitted to NMR Biomed)

• V.K. Shinoj, V.M. Murukeshan, S. Padmanabhan, P. Padmanabhan. “An integrated dual modality probe using double clad photonic crystal fiber and micro CCD camera for sensing and imaging application.” (submitted to Applied Optics)

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• B. Zheng, C. F. Schmidt, X. Golay. “Continuous Arterial Spin Labeling Perfusion Measurement Based on 3D-EPI Readout on Rats at 9.4T.” (submitted to Magn Reson Med)

In preparation:

• J. Hendrikse, E.T. Petersen, X. Golay, “A Study of Perfusion Territories in Stroke”

• E.T. Petersen, X. Golay, “An Automatic M0 Determination for the QUASAR Sequence”

• P. Padmanabhan, G. Johannes, ABMA. Asad, X. Golay. “Gastrointestinal transit measurements in mice with 99mTc-DTPA labeled activated charcoal using NanoSPECT-CT.”

• S. Padmanabhan, V.K. Shinoj, P. Padmanabhan, V.M. Murukeshan. “Highly sensitive optical detection of specific protein using Micro structured fiber in extremely low sample volume.”

Conference Abstracts Published:

• Y. Shen , R.A. Kauppinen , R. Vidyasagar , Y.-C.L. Ho , I. Zimine , E.T. Petersen , X. Golay, “Functional Magnetic Resonance Imaging Based on an Inversion Recovery Method for Grey Matter Signal Suppression”, Proc. 15th ISMRM, 27 (2007)

• Y.-C.L. Ho, R. Vidyasagar, Y. Shen, G. Balanos, X. Golay, R.A. Kauppinen, “Assessment of the BOLD Effect and Vascular Reactivity During Visual Stimulation in the Presence of Hypoxic Hypoxia”, Proc. 15th ISMRM, 110 (2007)

• E.T. Petersen, I. Zimine, Y.-C.L. Ho, X. Golay, “An Improved QUASAR Sequence for User-Independent Quantitative and Reproducible Perfusion Measurements”, Proc. 15th ISMRM, 376 (2007)

• Y.-C.L. Ho, E.T. Petersen, I. Zimine, X. Golay, “Hemodynamic Characteristics in Various Arteriolar Segments Upon Physiological Changes”, Proc. 15th ISMRM, 618 (2007)

• S.M. Chng, E.T. Petersen, I. Zimine, Y.Y. Sitoh, X. Golay, C.C.T. Lim, “Regional Perfusion Imaging Using Arterial Spin Labeling in the Assessment of Collateral Circulation – a Comparison with Digital Subtraction Angiography”, Proc. 15th ISMRM, 690 (2007)

• B.F. Coolen, P. Lee, B. Shuter, X. Golay, “Optimized MRI Parameters for Positive Contrast Detection of Iron-Oxide Labeled Cells Using Double-Echo Ultra-Short Echo Time (D-UTE) Sequences”, Proc. 15th ISMRM, 1224 (2007)

• E.T. Petersen, X. Golay, “Improved Inversion Efficiency in Arterial Spin Labeling Using Adiabatic Null Pulses”, Proc. 15th ISMRM, 1408 (2007)

• I. Teh, B. Zheng, J.V. Hajnal, X. Golay, D.J. Larkman, “Rapid Isotropic Diffusion Weighted Imaging Using PROPELLER”, Proc. 15th ISMRM, 1481 (2007)

• C.C.-H. Hong, J. C. Harris, G.D. Pearlson, J.-S. Kim, V.D. Calhoun, J.H. Fallon, X. Golay, J.S. Gillen, P.C.M. van Zijl, D.S. Zee, J.J. Pekar, “Multisensory Recruitment Associated with REM Sleep Eye Movements: An fMRI Study”, Proc. 15th ISMRM, 2024 (2007)

• C.L. Tosti, E.T. Petersen, J. Laothamatas, X. Golay, S.V. Swaminathan, M. Van Cauteren, J. Murdoch , V. Lekprasert, N. Tangpukdee, S. Krudsood, W. Leowattana, P. Wilairatana, R.L. DeLaPaz, T.R. Brown, S. Looareesuwan, G.M. Brittenham, “Cerebrospinal Fluid Lactate in P. Falciparum Malaria: Measurement by Chemical Shift Imaging at 3 Tesla”, Proc. 15th ISMRM, 2262 (2007)

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• M. Robinson, J. Wang, P.J. Eslinger, M. Meadowcroft, X. Golay, Q.X. Yang, “The Bold Signal Response Differences Between Encoding and Recognition Memory of Face-Name Associations”, Proc. 15th ISMRM, 3220 (2007)

• N.D. Gai , S.L. Talagala, X. Golay, F.G.C. Hoogenraad, J.A. Butman, “Evaluation of 3D-EPI PULSAR with and Without Background Suppression Inversion Recovery Pulse”, Proc. 15th ISMRM, 3486 (2007)

• I. Zimine, E.T. Petersen, X. Golay,“ Subtraction Errors in Regional Perfusion Imaging Using a Single Control Aquisition”, Proc. 15th ISMRM, 3490 (2007)

• E.T. Petersen, X. Golay, the QUASAR Reproducibility study, “Is Arterial Spin Labeling Ready for Prime Time? Preliminary results from the QUASAR Reproducibility Study”, Proc. 16th ISMRM, (2008)

• Y.-C.L. Ho, E.T. Petersen, X. Golay, “Dissociation of CBF responses corresponding to negative BOLD activity”, Proc. 16th ISMRM, (2008)

• M. Varela, J.V. Hajnal , E.T. Petersen , X. Golay , D.J. Larkman, “Rapid Blood T1 Calibration for Arterial Spin Labelling”, Proc. 16th ISMRM, (2008)

• P. Gall, E.T. Petersen, X. Golay, V. Kiselev, “Delay and Dispersion in DSC Perfusion Derived from a Vascular Tree Model Predicts ASL Measurements”, Proc. 16th ISMRM, (2008)

• C.F. Schmidt, B. W. Zheng, S. Graham, X. Golay, “The Effects of Ambient MRI Scanner-Generated Auditory Noise on Rat Auditory Perception at 9.4T”, Proc. 16th ISMRM, (2008)

• E.T. Petersen, I. Zimine, X. Golay, the QUASAR Reproducibility study, “Validation of User Independent Planning Tool for Consistent Data Acquisition in Multi-center Trials”, Proc. 16th ISMRM, (2008)

• E.T. Petersen, A. Cheze, V. Chua, N. Venketasubramanian, R.N. Gan, X. Golay, “Does Arterial Spin Labeling Have a Role in Stroke Imaging? Preliminary Results from a 180 First Time Stroke Patients Study”, Proc. 16th ISMRM, (2008)

• I. Teh, D.J. Larman, X. Golay, “Diffusion Weighted Fast Spin Echo PROPELLER at 9.4T”, Proc. 16th ISMRM, (2008)

• P. Padmanabhan, G. Johannes, ABMA. Asad and X. Golay. Gastrointestinal transit measurements in mice with 99mTc-DTPA labeled activated charcoal using NanoSPECT-CT. World Molecular Imaging congress (2008)

• E.-T. Ang, A. Tai, A. Abu Bakar Md Ali, F. Gomez-Pinilla, P. Lee, G. Xavier, S.Q. Lo, T.-W. Soong “Iron transporter DMT1 transgenic mouse as a model for oxidative stress: implications for neurodegenerative disease.” 9th Intl Conf AD/PD (2009)

Accepted:

• C.-T Yang, K. Kittigowittana, B. Zheng, K.-H. Chuang, R. W. Bates, X. Golay. “Development of Novel Intravascular Contrast Agents for MRI using Gadolinium Chelates.” Proc. 17th ISMRM, (2009)

• W. Chen, Y. Wang, K-H. Chuang, X. Golay, A. Qiu. “Automatic liver segmentation of 3D abdominal MR images of rodents.” Proc. 17th ISMRM, (2009)

• D-Y. Chen, K-H. Chuang, S. Dodd, A. Koretsky. “In vivo Tracing of Cortical Laminar Structure in the Rodent Olfactory System using Manganese-Enhanced MRI (MEMRI).” Proc. 17th ISMRM, (2009)

• P. Lee, X. Golay, G. K. Radda. “Dynamic Perfusion Study of Mouse Pancreas with an Intravascular Contrast Agent.” Proc. 17th ISMRM, (2009)

Lab of Metabolic Medicine

3 of 26

Journal papers Published:

• Gustavsson N, Lao Y, Maximov A, Chuang J-C, Kostromina E, Repa J, Li C, Radda GK, Südhof TC, Han W: Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice. Proceedings of the National Academy of Sciences of the United States of America 105:3992-3997, 2008.

• Yang G, Lim C-Y, Li C, Radda GK, Li C, Cao X, Han W: FoxO1 inhibits leptin regulation of POMC promoter activity by blocking STAT3 interaction with specificity protein 1. The Journal of Biological Chemistry 284(6):3719-3727, 2009.

Accepted:

• Zhang J, Luo R, Wu H, Wei S, Han W, Li G: Role of type Iα phosphatidylinositol-4-phosphate 5-kinase in insulin secretion, glucose metabolism, and membrane potential in INS-1 β-cells. (accepted for publication in the Endocrinology on Dec. 30, 2008)

• Gustavsson N, Wei S-H, Hoang DN, Lao Y, Zhang Q, Radda GK, Rorsman P, Südhof TC, Han W: Synaptotagmin-7 is a principal Ca2+-sensor for Ca2+-induced glucagon exocytosis in pancreas. (accepted for publication in The Journal of Physiology on Jan 19, 2009)

Under revision or in preparation: • Gustavsson N, Lim C-Y, Lou P-H, Radda GK, Han W: Functions of

synaptotagmins in endocrine secretion. (invited review to Bioscience Reports) • Kostromina E, Gustavsson N, Wang X, Radda GK, Li C, Han W: Glucose

intolerance and impaired insulin secretion in pancreas-specific STAT3 KO mice are associated with reduced microvasculature around pancreatic islets. (submitted to AJP-Endo, under revision for resubmission)

• Gustavsson N, Han W: Dysregulated glucagon secretion in diabetic development. (manuscript in preparation)

Conference Abstracts Published:

• Xiao XQ, Glavas MM, Kirigiti MA, Fisher S, Evans AE, Enriori PJ, Lim CY, Han W, Cowley MA, Smith MS, Grove KL: Chronic inflammation and impaired lipid metabolism are associated with increased insulin resistance susceptibility in neonatally overfed mice. Abstracts in the Endocrine Society, 90th Annual Meeting, San Francisco, 2008 (Poster).

• Yang G, Lim C-Y, Li C, Xiao X, Radda GK, Li C, Cao X, Han W: FoxO1 Inhibits leptin regulation of POMC promoter activity by blocking STAT3

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interaction with specificity protein 1. Abstract in Beijing Joint Conference of Physiological Sciences 2008, Beijing, China, 2008 (Poster).

• Gustavsson N, Wei S-H, Hoang DN, Lao Y, Zhang Q, Radda GK, Rorsman P, Südhof TC, Han W: Synaptotagmin-7 as the Major Ca2+-Sensor in Glucagon Secretion. Abstract in Beijing Joint Conference of Physiological Sciences 2008, Beijing, China, 2008 (Poster).

• Lu J, Han W: In vivo detection of GLUT4 trafficking. Abstract in The 7th International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2008), Wuhan, China, 2008 (Poster).

• Han W: Molecular mechanisms mediating calcium control of hormone secretion. Abstract in The 4th Scientific Meeting of Asia-Pacific Diabetes and Obesity Study Group, Kobe, Japan. 2008 (Invited talk)

• Gustavsson N, Lu J, Olivo M, Lee P, Chuang K-H, Golay X, Radda GK, Han W: In vivo detection of pancreatic β-cell mass and insulin secretory events. Abstract in The 7th International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2008), Wuhan, China, 2008 (Invited talk).

• Gustavsson N, Lu J, Olivo M, Radda GK, Han W: In vivo detection of insulin secretory events. Abstract in 2008 World Molecular Imaging Congress, Nice, France, 2008 (Poster).

• Xiao XQ, Su MYF, Lim CY, Glavas MM, Smith MS, Grove KL, Radda GK, Han W: Neonatal overfeeding exacerbates high fat diet induced hepatic steatosis and damage via metabolic programming. Abstract in Keystone Symposia: Type 2 Diabetes and Insulin Resistance (J3), Banff, Alberta, Canada, 2009 (Poster)

Biomedical Imaging Lab Since transfer to SBIC: Journal papers Published:

• Nowinski WL, Belov D, Pollak P, Benabid AL: Statistical analysis of 168 bilateral subthalamic nucleus implantations by means of the probabilistic functional atlas. Neurosurgery 2005, 57(4 Suppl): 319-330.

• Nowinski WL, Bhanu Prakash KN: Dorso-ventral extension of the Talairach transformation and its automatic calculation for MR Neuroimages. Journal of Computer Assisted Tomography 2005, 29(6):863-79.

• Nowinski WL, Belov D: Toward atlas-assisted automatic interpretation of MRI morphological brain scans in the presence of tumor. Academic Radiology 2005, 12(8):1049-57. (Academic Radiology, Erratum Volume 12, Issue 10, October 2005, Page 1355).

• Nowinski WL: The Cerefy brain atlases: continuous enhancement of the electronic Talairach-Tournoux brain atlas. Neuroinformatics 2005, 3(4):293-300.

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• Nowinski WL: Informatics in radiology (infoRAD): multimedia extension of medical imaging resource center teaching files. Radiographics 2005, 25(6):1699-708.

• Nowinski WL, Belov D, A. Thirunavuukarasuu, Benabid AL: A probabilistic functional atlas of the VIM nucleus constructed from pre-, intra- and post-operative electrophysiological and neuroimaging data acquired during the surgical treatment of Parkinson’s disease patients, Stereotactic and Functional Neurosurgery 2005, 83:190-196.

• Hu Q, Qian G, Nowinski WL: Fast connected-component labeling in three-dimensional binary images based on enhanced recursion. Journal Computer Vision and Image Understanding 2005, 99: 414-434.

• Hu Q, Nowinski WL. Thresholding magnetic resonance images of human brain. Chinese Journal of Interventional Imaging and Therapy 2005, 2(6): 460-469.

• Nowinski WL, Qian G, Bhanu Prakash KN, Hu Q, Aziz A: Fast Talairach Transformation for magnetic resonance neuroimages. Journal of Computer Assisted Tomography 2006, 30(4):629-41.

• Nowinski WL, Liu J, A. Thirunavuukarasuu: Quantification of three-dimensional inconsistency of the subthalamic nucleus in the Schaltenbrand-Wahren brain atlas. Stereotactic and Functional Neurosurgery Stereotactic and Functional Neurosurgery 2006, 84(1):46-55.

• Ma X, Zhao L, Volkau I, Zheng W, A Aziz, Ang M H Jr, Nowinski WL: A virtual reality simulator for interventional tele-radiology: concept, design, and initial validation. IEEE Transaction in Biomedical Engineering 2006, 53(8):1696-700.

• Hou Z: A review on MR image intensity inhomogeneity correction. International Journal of Biomedical Imaging, vol. 2006, Article ID 49515, 2006:1-11.

• Volkau I, Prakash B, Ananthasubramaniam A, Gupta V, Aziz A, Nowinski WL: Quantitative analysis of brain asymmetry by using the divergence measure: normal-pathological brain discrimination. Academic Radiology 2006, 13(6):752-8.

• Nowinski WL, Bhanu Prakash KN, Volkau I, Ananthasubramaniam A, Beauchamp NJ: Rapid and automatic calculation of the midsagittal plane in magnetic resonance diffusion and perfusion images. Academic Radiology 2006, 13(5):652-663.

• Bhanu Prakash KN, Nowinski WL, Morphological relationship among the corpus callosum, fornix, anterior commissure and posterior commissure: MRI-based variability study. Academic Radiology 2006, 13(1):24-35.

• Bhanu Prakash KN, Hu Q, Aziz A, Nowinski WL: Rapid and automatic localization of the anterior and posterior commissure point landmarks in MR volumetric neuroimages. Academic Radiology 2006, 13(1):36-54.

• Nowinski WL: Virtual reality in brain intervention. International Journal of Artificial Intelligence Tools 2006, 15(5):741-752.

• Lim TCC, Yang GL: Electronic teaching files and continuing professional development in radiology. Biomedical Imaging and Intervention Journal 2006,2(2):e5.

• Liu J, Nowinski WL: A hybrid approach to shape-based interpolation of stereotactic atlases of the human brain. Neuroinformatics 2006, 4(2): 177-198.

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• Lakshimpathy J, Nowinski WL, Wernert E A: Template-based isocontouring. Special Issue of Bio VR with the International Journal of Images and Graphics 2006, 6(2):187-204.

• Bott OJ, Wagner M, Teistler M, Duwenkamp C, Ahrens CA, Kimmel R, Lörchner A, Raab B, Stürmer KM, Pretschner DP, Dresing K: VirtX – a computer based system for training the intrasurgical use of a mobile image intensifier system. GMS Med Inform Biom Epidemiol 2006, 2(3):Doc16.

• Roy A, Nowinski WL, Tay F E H, Baimouratov R: A Meshed Atlas Visualization Toolkit in a Java-based CAD Platform. Daffodil International University Journal of Science and Technology 2006,1(1):11-20.

• Yang GL, Lim CCT: Creating teaching files. Biomedical Imaging and Intervention Journal 2006, 2(4):e53.

• Hou Z, Hu Q, Nowinski WL: On minimum variance thresholding. Pattern Recognition Letters 2006,27:1732-1743.

• Bhanu Prakash KN, Gupta V, Bilello M, Beauchamp NJ, Nowinski WL: Identification, segmentation and image property study of acute infarcts in diffusion-weighted images by using a probabilistic neural network and adaptive Gaussian mixture model. Academic Radiology 2006, 13(12):1474-1484.

• Ng HP, SH Ong, Hu Q, Foong KWC, Goh PS, Nowinski WL: Muscles of mastication model-based MR image segmentation. International Journal of Computer Assisted Radiology and Surgery 2006, 1(3):137-148.

• Volkau I, Bhanu Prakash KN, Anand A, Aziz A, Nowinski WL: Extraction of the midsagittal plane from morphological neuroimages using the Kullback-Leibler’s measure. Medical Image Analysis 2006, 10(6):863-874.

• Qiao Y, Hu Q, Qian G, Nowinski WL: Thresholding based on variance and intensity contrast. Pattern Recognition 2006, 40(2):596-608.

• Nowinski WL, Liu J, Thirunavuukarasuu A: Quantification and visualization of three-dimensional inconsistency of the globus pallidus internus in the Schaltenbrand-Wahren brain atlas. Stereotactic and Functional Neurosurgery 2006, 84:236-242.

• Yang GL, Lim CCT, Singapore National Medical Image Resource Center (SN.MIRC): A World Wide Web resource for radiology education. ANNALS Academy of Medicine Singapore 2006, 35:558-563.

• Marschollek M, Teistler M, Bott OJ, Stuermer KM, Pretschner DP, Dresing K: Pre-operative dynamic interactive exploration of complex articular fractures using a novel 3D navigation tool. Methods of Information in Medicine Methods of Information in Medicine 2006, 45(4):384-388.

• Nowinski WL, Qian G, Bhanu Prakash KN, Thirunavuukarasuu A, Hu QM, Ivanov N, Parimal AS, Runge VL, Beauchamp NJ: Analysis of ischemic stroke MR images by means of brain atlases of anatomy and blood supply territories. Academic Radiology 2006,13(8):1025-1034.

• Gao C, Tay F E H, Nowinski WL: Finite element modeling of an inhomogeneous brain for neurosurgery applications. International Journal of Computer Assisted Radiology and Surgery 2006, 1 (Supp1. 1):152-154.

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• Gao C, Tay F E H, Ng WH, Ang BT, Yeo TT, Nowinski WL: Modeling brain deformation induced by ventriculoperitoneal shunting. International Journal of Computer Assisted Radiology and Surgery 2006, 1 (Supp1. 1):299-300.

• Hu Q, Nowinski WL: Radiological symmetry of brain and head images: comparison and applications. International Journal of Computer Assisted Radiology and Surgery 2006,1(2):75-81.

• Nowinski WL, Qian GY, Bhanu Prakash KN, Volkau I, Hu Q, Thirunavuukarasuu A, Ivanov N, Parimal AS, Qiao Y, Ananthasubramaniam A, Huang S, Runge VM, Beauchamp NJ: Design and development of a computer aided diagnosis system for processing of acute ischemic stroke MR images. WSEAS Transactions on Biology and Biomedicine 2006, 3(6):401-407.

• Huang S, Baimouratov R, Volkau I, Nowinski WL: IVME: A tool for editing, manipulation, quantification, and labeling of cerebrovascular models. Computerized Medical Imaging and Graphics 2006, 30(3):187-95.

• Qiao Y, Ong SH: Arc-based evaluation and detection of ellipses. Pattern Recognition 2007, 40(7):1990-2003.

• Teistler M, Breiman RS, Sauw ML, Liang Yoong Ho, Atif Shahab, Nowinski WL: Interactive definition of transfer functions in volume rendering based on image markers. International Journal of Computer Assisted Radiology and Surgery 2007, 2(1):55-64.

• Ng HP, Hu Q, Ong SH, Foong KWC, Goh PS, Liu J, Nowinski WL: Segmentation of the temporalis muscle from MR data. International Journal of Computer Assisted Radiology and Surgery 2007, 2(1):19-30.

• Xiao GY, Aziz A, Nowinski WL: Hybrid image-based collision detection in Java 3D. Software - Practice and Experience 2007, 37(9):963-982.

• Liu J, Huang S, Aziz A, Nowinski WL. Three dimensional digital atlas of the orbit constructed from multi-modal radiological images. International Journal of Computer Assisted Radiology and Surgery 2007, 1(5):275-283.

• Yang GL, Tan YF, Loh SC, Lim CCT: Neuroradiology Imaging Database: using picture archive and communication systems (PACS) for brain tumor research. Singapore Medical Journal 2007, 48(4):342.

• Nowinski WL, Thirunavuukarasuu A, Liu J, Benabid AL: Correlation between the anatomical and functional human subthalamic nucleus. Stereotactic and Functional Neurosurgery 2007, 85:88-93.

• Ng H, Foong KWC, Ong SH, Liu J, Nowinski WL: Shape determinative slice localization for patient-specific masseter modeling using shape-based interpolation. International Journal of Computer Assisted Radiology and Surgery 2007, 2(Suppl. 1):398-400.

• Nowinski WL, Qian G, Bhanu Prakash KN, Volkau I, A. Thirunavuukarasuu, Hu Q, A. Ananthasubramaniam, Liu J, Gupta V, Ng TT, Leong WK, Beauchamp NJ: A CAD system for acute ischemic stroke image processing. International Journal of Computer Assisted Radiology and Surgery 2007, 2(Suppl. 1):220-222.

• Toh DJ, Ma X, Nowinski WL: Simulator with anatomic variations for interventional radiology training. International Journal of Computer Assisted Radiology and Surgery 2007, 2(Suppl. 1):139-141.

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• Hu Q: Selection of symmetry measures and image features for extracting the midsagittal plane from neuroimages: local symmetry versus global symmetry and gray level versus edge. International Journal of Computer Assisted Radiology and Surgery 2007, 2(Suppl. 1):S85-S87.

• Hou Z, Qian W, Hu Q, Huang S, Nowinski WL: Regularized fuzzy c-means method for brain tissue clustering. Pattern Recognition Letters 2007, 28(13):1788-1794.

• Nowinski WL: From research to clinical practice: lessons learnt from the Cerefy brain atlases. International Journal of Computer Assisted Radiology and Surgery 2007, 2(3-4):211-220.

• Gupta V, Bhanu Prakash KN, Nowinski WL: Towards discrimination of infarcts from artifacts in DWI scans. International Journal of Computer Assisted Radiology and Surgery 2008, 2(6):385-395.

• Teistler M, Breiman R, Lison T, Bott OJ, Pretschner DP, Aziz A, Nowinski WL: Simplifying the exploration of volumetric images: Development of a 3D user interface for the radiologist's workplace. Journal of Digital Imaging 2008, 21(2): 2-12.

• Hou Z, Huang S: Characterization of a sequential pipeline approach to automatic tissue segmentation from brain MR images. International Journal of Computer Assisted Radiology and Surgery 2008, 2(5): 305-316.

• Hu Q, Qian G, Teistler M, Huang S. Informatics in radiology: automatic and adaptive brain morphometry on MR images. Radiographics 2008, 28(2):345-56.

• Ng HP, SH Ong, Foong KWC, Goh PS, Nowinski WL: Masseter image segmentation using an improved watershed algorithm with unsupervised classification. Computers in Biology and Medicine 2008, 38(2):171-184.

• Gupta V, Bhanu Prakash KN, Nowinski WL: Automatic and rapid identification of infarct slices and hemisphere in DWI scan. Academic Radiology 2008, 15(1):24-39.

• Nowinski WL: Towards construction of an ideal stereotactic brain atlas. Acta Neurochirurgica 2008, 150(1):1-14.

• Volkau I, Ng TT, Marchenko Y, Nowinski WL: On geometric modeling of the human intracranial venous system. IEEE Transactions on Medical Imaging 2008, 27(6):745-751.

• Nowinski WL, Liu J, Thirunavuukarasuu A: Quantification and visualization of three-dimensional inconsistency of the ventrointermediate nucleus of the thalamus in the Schaltenbrand-Wahren brain atlas. Acta Neurochirurgica 2008, 150(7):647-653.

• Liu J, Huang S, Nowinski WL: A volumetric model-based local segmentation approach for automatic 3D point landmark localization in neuroimages. IEEE Transactions on Medical Imaging 2008, 27(8):1034-1044.

• Liu J, Huang S, Nowinski WL: A hybrid approach for segmentation of anatomic structures in medical images. International Journal of Computer Assisted Radiology and Surgery 2008, 3(3-4):213-219.

• Ng HP, Ong SH, Foong KWC, Goh PS, Nowinski WL: Fuzzy C-Means (FCM) algorithm with local thresholding. International Journal on Artificial Intelligence Tools 2008, 17(4)765-775.

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• Ng HP, Liu J, Huang S, Ong SH, Foong KWC, Goh PS, Nowinski WL: An improved shape determinative slice determination method for patient-specific modeling of facial anatomical structure. International Journal of Computer Assisted Radiology and Surgery 2008, 3(3-4):221-230.

• Bott OJ, Teistler M, Duwenkamp C, Wagner M, Marschollek M, Plischke M, Raab BW, Stürmer KM, Pretschner DP1, Dresing K: virtX – evaluation of a computer based training system for mobile C-arm systems in trauma and orthopedic surgery. Methods of Information in Medicine 2008, 47(3):270-8.

• Gupta V, Bhanu Prakash KN, Nowinski WL: Towards discrimination of infarcts from artifacts in DWI scans. International Journal of Computer Assisted Radiology and Surgery 2008, 2(6):385-395.

• Hou Z, Huang S: Characterization of a sequential pipeline approach to automatic tissue segmentation from brain MR images. International Journal of Computer Assisted Radiology and Surgery 2008, 2(5):305-316.

• Hu Q, Qian G, Teistler M, Huang S. Informatics in radiology: automatic and adaptive brain morphometry on MR images. Radiographics 2008,28(2):345-56.

• Nowinski WL, A Thirunavuukarasuu, Volkau I, Marchenko Y, Aminah B, Gelas A, Huang S, Lee LC, Liu J, Ng TT, Nowinska N, Puspitasari F, Qian G, Runge VM: A new presentation and exploration of human cerebral vasculature correlated with surface and sectional neuroanatomy. Anatomical Sciences Education 2009, 2(1):24-33.

• Nowinski WL, Volkau I, Marchenko Y, A Thirunavuukarasuu, Ng TT, Runge VM: A 3D model of the human cerebrovasculature derived from 3 tesla magnetic resonance angiography. Neuroinformatics 2009, 7(1) 23-36.

In press:

• Marchenko Y, Volkau I, Nowinski WL: Vascular Editor: from images to 3D vascular models. Journal of Digital Imaging 2008 (in press).

Accepted:

• Qian G, Luo S, Jin J, Park M, Nowinski WL: Automated and domain knowledge-based brain extraction from CT head scans. International Journal of Computer Aided Engineering and Technology 2008.

• Ng HP, Ong SH, Huang S, Liu J, Foong KWC, Goh PS, Nowinski WL:Salient features useful for the accurate segmentation of masticatory muscles from minimum slice subsets of magnetic resonance images. Machine Vision and Applications 2008 (online version published on 14 October 2008).

• Bhanu Prakash KN, Gupta V, Hu J, Nowinski WL: Automatic processing of diffusion-weighted ischemic stroke images based on divergence measures: slice and hemisphere identification, and stroke region segmentation. International Journal of Computer Assisted Radiology and Surgery (online version published on 21 October 2008).

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• Liu J, Huang S, Nowinski WL: Registration of brain atlas to MR images using topology preserving front propagation. Journal of Signal Processing 2008 (online published on 6 May 2008).

• Ng HP, Ong SH, Liu J, Huang S, Foong KWC, Goh PS, Nowinski WL: 3D segmentation and quantification of a masticatory muscle from MR data using patient-specific models and matching distributions. Journal of Digital Imaging 2008 (online published on 31 May 2008).

• Ng HP, Foong KWC, Ong SH, Goh PS, Huang S, Liu J, Nowinski WL: Quantitative analysis of human masticatory muscles using magnetic resonance imaging. Dentomaxillofacial Radiology 2008.

• Kang Sim, Yang GL, Poon LY, Donus Loh, Lilyn Leow, Sitoh YY, Keefe R, Heckers S, Collinson S, Verma S, Chong SA,, Nowinski WL, Pantelis C: Passivity Phenomenon in Schizophrenia: Cerebral White Matter Disruptions and Clinical Correlates. Psychiatry Research: Neuroimaging. 2009.

• Kang Sim, Yang GL, Poon LY, Donus Loh, Lilyn Leow, Sitoh YY, Keefe R, Heckers S, Collinson S, Verma S, Chong SA,, Nowinski WL, Pantelis C: Passivity Phenomenon in Schizophrenia: Cerebral White Matter Disruptions and Clinical Correlates. Journal of Clinical Psychiatry 2009.

• Gelas A, Valette S, Prost R, Nowinski WL: Variational implicit surface meshing. Computers & Graphics 2009.

Abstracts in journals Published:

• Nowinski WL, Hu Q, Bhanu Prakash, Volkau I, Qian G, Thirunavuukarasuu A, Liu J, Aziz A, Baimouratov R, Hou Z, Huang S, Luo S, Minoshima S, Runge V, Beauchamp N: Atlas-assisted analysis of brain scans. Book of Abstracts of European Congress of Radiology ECR 2005, 4-8 March 2005, Vienna, Austria. European Radiology, Supplement 1 to Volume 15, Feb 2005:572.

• Nowinski WL, Thirunavuukarasuu A, Fu Y, Ma X, Lin Z, Wang S: The Cerefy Atlas of Brain Anatomy in Chinese. Book of Abstracts of European Congress of Radiology ECR 2005, 4-8 March 2005, Vienna, Austria. European Radiology, Supplement 1 to Volume 15, Feb 2005:572.

• Aziz A, S. K. Venkatesh, Xiao G, E. K. W. Sim, Nowinski WL, S. C. Wang: Electronic thoracic atlas generated from high resolution computed tomography - Use in minimally invasive Cardiothoracic Surgery planning. Book of Abstracts of European Congress of Radiology ECR 2005, 4-8 March 2005, Vienna, Austria. European Radiology, Supplement 1 to Volume 15, Feb 2005:429.

• Liu J, Nowinski WL: A model-based interactive approach for building 3D anatomical models. International Journal of Computer Assisted Radiology and Surgery 2007, Berlin, Germany, 2(Suppl1):S458.

• Liu J, Gao W, Fu Y, Nowinski WL: 3D segmentation of the basal ganglia using active appearance models and shape-based interpolation. International Journal

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of Computer Assisted Radiology and Surgery 2007, Berlin, Germany, 2(Suppl1):S461.

• Aziz A, Yang GL, Lusby W: Application of multimedia augmented web based remote radiology teaching system. Journal Compilation, The Royal Australian and New Zealand College of Radiologists 2007: A57.

• Nowinski WL, Qian GY, Bhanu Prakash KN, Volkau I, Gupta V, Puspitasari F, Hu J, Liu J, Huang S, Kaźmierski R, Ambrosius W, Urbanik A, Chrzan R, Beauchamp NJ: Computer-aided, atlas-assisted processing and quantification of CT and MR scans in stroke. Neuroradiology, European Society of Neuroradiology, ESNR 2008, Vol. 50 Suppl 1:S66.

• Nowinski WL, A Thirunavuukarasuu, Volkau I, Marchenko Y, Aminah B, Puspitasari F, Nowinska N, Ng TT, Qian GY, Liu J, Huang S, Gelas A, Lee LC, Knopp MV, Runge VM: Cerebral vasculature in three dimensions and its correlation with imaging neuroanatomy based on 3T and 7T acquisitions. European Society of Neuroradiology, ESNR 2008, Vol. 50 Suppl 1:S67.

Accepted:

• Nowinski WL, A Thirunavuukarasuu, Volkau I, Marchenko Y, Aminah B, Puspitasari F, Nowinska NG, Knopp MV, Runge VM. Three-dimensional atlases of cerebral vasculature and its variability derived from 3T and 7T multi-modal acquisitions. ECR 2009, European Radiology.

Full Conference Papers Published:

• Nowinski WL, Liu J, Volkau I: Geometric modeling of cerebral structures. Proc. on CD-ROM 12th International Conference on Biomedical Engineering ICBME 2005, 7-10 December 2005, Singapore (invited).

• Gao CP, Ng WH, Loh JS, Yeo TT, Tay FEH, Nowinski WL: A finite element analysis of ventriculoperitioneal shunting. Proc. on CD-ROM 12th International Conference on Biomedical Engineering ICBME 2005, 7-10 December 2005, Singapore: 2A5-10.

• Li Yang, Volkau I, Nowinski WL: Probabilistic cerebrovascular atlas: statistical modeling of vascular variability using a random graph. Proc. on CD-ROM 12th International Conference on Biomedical Engineering ICBME 2005, 7-10 December 2005, Singapore: 4A1-08.

• Li Yang, Volkau I, Huang S, Nowinski: Design of an environment for creation and manipulation of the probabilistic cerebrovascular atlas. Proc. on CD-ROM 12th International Conference on Biomedical Engineering ICBME 2005, 7-10 December 2005, Singapore: 4A2-06.

• HP Ng, Foong KWC, Ong SH, Goh PS, Nowinski WL: An improved watershed algorithm for medical image segmentation. Proc. on CD-ROM 12th International

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Conference on Biomedical Engineering ICBME 2005, 7-10 December 2005, Singapore: 2B2:06

• HP Ng, Ong SH, Foong KWC, Nowinski WL: Moving towards the construction of a highly realistic pre-surgical facial model. Proc. on CD-ROM 12th International Conference on Biomedical Engineering ICBME 2005, 7-10 December 2005, Singapore: 1B3-05.

• Nick Ivanov, A S Parimal, Nowinski WL: Fast warping of brain image against atlas with special class of radial basis functions. Proc. on CD-ROM 12th International Conference on Biomedical Engineering ICBME 2005, 7-10 December 2005, Singapore: 4A2-01.

• Hou Z: Wavelet shrinkage prefiltering for brain tissue segmentation. Proc. on CD-ROM 27th Annual International Conference IEEE Engineering in Medicine and Biology Society conference Shanghai, China, 1-4 September 2005.

• Gao CP, Tay EH, Nowinski WL: A finite element method based deformable brain atlas suited for surgery simulation. Proc. on CD-ROM 27th Annual International Conference IEEE Engineering in Medicine and Biology Society conference Shanghai, China, 1-4 September 2005.

• Hu QM, Qian GY, Aziz A, Nowinski WL: Segmentation of brain from computed tomography head images. Proc. on CD-ROM 27th Annual International Conference IEEE Engineering in Medicine and Biology Society conference Shanghai, China, 1-4 September 2005.

• Nowinski WL: Virtual reality in brain intervention: models and applications. Proc. on CD-ROM 27th Annual International Conference IEEE Engineering in Medicine and Biology Society conference Shanghai, China, 1-4 September 2005.

• Nowinski WL: Current status and future research activities in clinical neuroinformatics: Singaporean perspective. Proc. First International Conference on Natural Computation (ICNC'05) and Second International Conference on Fuzzy Systems and Knowledge Discovery (FSKD'05), 27-29 August 2005, Changsha, China (invited):1065-1073.

• Luo A, Lee SY, Ma X, Aziz A, Hu Q, Nowinski WL: Automatic extraction of cerebral arteries: algorithm and validation. Proc. Computer Assisted Radiology and Surgery, CARS 2005, 19th International Congress and Exhibition, 22 – 25 June 2005 Berlin, Germany: 375-380.

• Hu Q, Nowinski WL: Robust and accurate segmentation of brain from T1-weighted MR head volumes based on local thresholding and mathematical morphology. The First International Conference on Complex Medical Engineering-CME2005, 15-18 May 2005:265-270.

• Luo S, Hu Q, Nowinski, WL: Automatic MRA cerebral vasculature segmentation with robust multiscale 3D searching and region growing. The First International Conference on Complex Medical Engineering-CME2005, 15-18 May 2005:750-753.

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• Nowinski WL: Human brain atlases in education, research, and clinical applications. The First International Conference on Complex Medical Engineering-CME2005, 15-18 May 2005 (invited paper):68-73.

• Ng HP, Foong W C, Kelvin, Ong S H, Nowinski WL: Towards construction of 3D virtual human head for clinical purposes. The First International Conference on Complex Medical Engineering-CME2005, 15-18 May 2005:297-301.

• Roy A, Tay F E H, Nowinski WL: FEM analysis of a detailed anatomical human brain model according to cerefy brain atlas. The First International Conference on Complex Medical Engineering-CME2005, 15-18 May 2005:947-951.

• Ng HP, Ong SH, Goh PS, Foong KWC, Nowinski WL: Template-based automatic segmentation of facial masseter using prior knowledge. Proc. IEEE Southwest Symposium on Image Analysis and Interpretation, USA, March 26-28, 2006:208-212.

• Ng HP, Ong SH, Foong KWC, Goh PS, Nowinski WL: Medical image segmentation using k-means and improved watershed algorithm. Proc. IEEE Southwest Symposium on Image Analysis and Interpretation, USA, March 26-28, 2006:61-65.

• Roy A, Nowinski WL, Tay FEH: Construction of physics-based atlas and its application in brain deformation analysis. Journal of Physics Conference Series, International MEMS Conference 2006, Singapore, 2006,34: 752-756.

• Hu Q, Qian GY, Nowinski WL: Fast and robust segmentation of head in T1-weighted magnetic resonance volume. 9th International Conference on Control, Automation, Robotics and Vision, ICARCV2006, 5-8 December 2006:1430-1433.

• Parimal AS, Ivanou N, Nowinski WL: Transformation of images by radial basis functions with varying centre point. The 9th International Conference on Control, Automation, Robotics and Vision, ICARCV2006, 5-8 December 2006:2401-2405.

• Hu Q, Qiao Y, Luo S, Qian G, Nowinski WL: Grayscale thresholding by incorporating prior knowledge. Asia-Pacific Workshop on Visual Information Processing, VIP2006, 7 - 9 November 2006, Beijing, China, 2006:275-280.

• Hou Z, Huang Su, Hu Q, Nowinski WL: Fast and automatic method to correct intensity inhomogeneity in MR brain images. Proc 9th Medical Image Computing & Computer Assisted Intervention 2006, 1 – 6 October 2006, Copenhagen, Denmark, LNCS Vol. 4191/2006:324-331.

• Ng HP Ong SH, Foong KWC, Goh PS, Nowinski WL: Knowledge-driven 3-D Extraction of the Masseter from MR data. The 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, August 30 - September 3, 2006: 5294-5297.

• HP Ng, SH Ong, KWC Foong, PS Goh, WL Nowinski: Automatic segmentation of facial muscles of mastication from magnetic resonance images using prior

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knowledge. Proceedings 18th IAPR International Conference on Pattern Recognition, 20 – 24 August, Hong Kong, 2006, Vol 3: 968-971.

• Nowinski WL, Qian GY, Bhanu Prakash KN, Volkau I, Hu Q, Thirunavuukarasuu A, Ivanov N, Parimal AS, Qiao Y, Ananthasubramaniam A, Huang S, Runge VM, Beauchamp NJ: Computer-aided diagnosis design and development of a system for stroke MR image processing. WSEAS Conference Cellular and Molecular Biology Biophysics and Bioengineering (BIO'06) Greece, 14 – 16 July 2006:20-25.

• Nowinski WL: Processing of neuroimages in a clinical setting. Asian Forum on Medical Imaging 2007, 26-27 January, Korea, IEICE Technical Report Vol. 106 No 509:39-42.

• Nowinski WL, Thirunavuukarasuu A: Anatomical and electro physiology-based atlases as well as atlas-based planning. Proc. 10th Annual Conference of the Indian Society for Stereotactic & Functional Neurosurgery, Kolkata, India,13-14 October 2007:63-73.

• Nowinski WL: Atlas-based planning: Biomedical Imaging Lab experience. Proc. 10th Annual Conference of the Indian Society for Stereotactic & Functional Neurosurgery, Kolkata, India, 13-14 October 2007:78-85.

• Nowinski WL, Qian G, Bhanu Prakash KN, Volkau I, Leong WK: CAD systems for ischemic and hemorrhagic strokes. Proc. Medical Imaging and Informatics MIMI2007, Beijing, China, August 14–16 2007: 320-330.

• Ng HP, Foong KWC, Ong SH, Goh PS, Nowinski WL: Medical image segmentation using feature-based GVF snake. 29th Annual International Conference IEEE Engineering in Medicine and Biology Society, Lyon, France, 23-26 August 2007:800-803.

• Ng HP, Foong KWC, Ong SH, Liu J, Goh PS, Nowinski WL: A study on shape determinative slices for the masseter muscle. 29th Annual International Conference IEEE Engineering in Medicine and Biology Society, Lyon, France, 23-26 August 2007: 5585-5588.

• Li Yang� Tan TS� Volkau I, Nowinski WL: Model-guided segmentation of 3D neuroradiological image using statistical surface wavelet model. IEEE Proc. Computer Vision and Pattern Recognition, 2007 CVPR '07, Minneapolis, Minnesota, USA, 18 - 23 June 2007:1 – 7.

• Ng HP, Huang S, Ong SH, Foong KWC, Goh PS, Nowinski WL: Medical image segmentation using watershed segmentation with texture-based region merging. 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2008,Vancouver, Canada, 20-24 August 2008: 4039-4042.

• Wong W, Le TM, Volkau I, Thirunavuukarasuu A, Ng HP, Nowinski WL: Estimation and presentation of blood flow and velocity from radiological images of arterial system in the human brain. 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2008: Vancouver, Canada, 20-24 August 2008: 4936-3939.

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• Qian G, Luo S, Jin J, Park M, Nowinski WL: Interactive and intelligent approach for brain extraction from high-resolution volumetric MR neuroimages. International Symposium on Intelligent Information Technology Application (IITA’08), Shanghai, China, 22-23 December 2008: 2:885-889.

Conference Abstracts Published:

• Breiman R, Durack J, Breiman L, Teistler M: A high resolution interactive stereoscopic 3D display for medical diagnosis, treatment planning, and education. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005.

• Ma X, Zhao L, Aziz A, Zaoli Z, Jeremy LOH, Nowinski WL: The use of impedance sensors for intravascular navigation based on landmarks and a virtual map. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:864.

• Narayanaswami B, Aziz A, Yang GL, Ananthasubramaniam A, Lim TCC, Nowinski WL: Multi-media medical image discussion forum. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:857.

• Yang GL, Narayanaswami B, Aziz A, Ananthasubramaniam A, Lim TCC, Nowinski WL: Web based interactive radiology examination system. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:863.

• Nowinski WL, Qian GY, Bhanu Prakash KN, Volkau I, A. Thirunavuukarasuu, Beauchamp NJ, Runge VW, Ananthasubramaniam A, Liu J, Qiao Y, Hu Q, Bilello: Atlas-assisted MR stroke image interpretation by using anatomical and blood supply territories atlases. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:857.

• Nowinski WL, Qian GY, Hu Q, KN Bhanuprakash, Ivanov N, Huang S, AS Parimal, Liu J: Fast and automatic interpretation of normal morphological brain scans by using an atlas with non-linear warping. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:857.

• Teistler M, Breiman RS, Ho LY, Liong SM, Shahab A, Nowinski WL: See what you want to see: Easy definition of color map for volume rendering and related image processing techniques. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:863-864.

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• Teistler M, Breiman RS, Nowinski WL: Facilitating the radiologist’s viewing process: Introduction of low-cost camera-based user interface to complement keyboard and mouse. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:863.

• Volkau I, Aziz A, Bhanu Prakash KN, Anand A, Teistler M, Nowinski WL: Visualization of brain asymmetries caused by abnormality. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:857.

• Volkau I, Narayanaswami B, Nowinski WL: A vascular editor for creation and enhancement of vascular trees from angiography data. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:684.

• Yang GL, Lim CCT, Hou Z, Gan R, Nowinski WL: A practical computer aided diagnosis system for intracranial hemorrhage detection in acute stroke. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:856-857.

• Yang GL, Lim CCT, Narayanaswami B, Nowinski WL: Multilingual support: Internationalization of MIRC. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November - 2 December 2005:868.

• Nowinski WL, Thirunavuukarasuu A, Benabid AL: Stereotactic targeting by using a combined anatomic-neurophysiologic brain atlas. 13th World Congress of Neurological Surgery 2005, Morocco Marrakech, 19-24 June 2005:1679.

• Nowinski WL, Thirunavuukarasuu A, Benabid AL: Functional neurosurgery planning assisted by the probabilistic functional atlas of the VIM nucleus co-registered with the Schaltenbrand-Wahren atlas. 14th Meeting of the World Society for Stereotactic and Functional Neurosurgery, Rome, 13-17 June 2005:143-145.

• Nowinski WL, Volkau I, Bhanu Prakash KN, Ananthasubramaniam A, Ivanov N, Beauchamp N: Automatic interpretation of stroke images by means of an anatomical atlas. American Society of Neuroradiology merican Society of Neuroradiology, ASNR 43rd Annual Meeting Metro Toronto Convention Centre, Canada, May 21-27, 2005: 427.

• Nowinski WL, Volkau I , Baimouratov R, Thirunavuukarasuu A, Hu Q, Luo S, Huang S, Runge V: A reference atlas of cerebral vasculature. American Society of Neuroradiology, ASNR 43rd Annual Meeting Metro Toronto Convention Centre, Canada, May 21-27, 2005: 441.

• Nowinski WL, Belov D, Thirunavuukarasuu A, Benabid AL: A probabilistic functional atlas of the VIM nucleus. American Association of Neurological Surgeons, New Orleans, Louisiana, USA, 16 – 21 April 2005.

• Nowinski WL, Qian G, Bhanu Prakash KN, Volkau I, A Thirunavuukarasuu, Liu J, Ananthasubramaniam A, Qiao Y, Hu Q, Runge V, Beauchamp NJ: A

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CAD system for stroke MR. Proc. American Society of Neuroradiology 44th Annual Meeting, ASNR 2006, San Diego, USA April 29 – May 5 2006: 425-426.

• Hu Q, Qian G, Teistler M, Nowinski WL: Automatic and adaptive brain morphometry of magnetic resonance scans. Program 92 Radiological Society of North America Scientific Assembly and Annual Meeting Program 2006, Chicago USA, 25 November – 1 December 2006:784.

• S Suresh MD, Guo Liang, Karen, Bhanu Prakash, Dr Indrani S, Nowinski WL: Atlas of fetal CNS anomalies from multi-dimensional Ultrasound. Program 92 Radiological Society of North America Scientific Assembly and Annual Meeting Program 2006, Chicago, USA, 25 November – 1 December 2006:904.

• Ma X, Liu J, Volkau I, Marchenko Y, Nowinski WL: A training simulator for interventional radiology with user-defined vascular models. Program 92 Radiological Society of North America Scientific Assembly and Annual Meeting Program 2006, Chicago, USA, 25 November – 1 December 2006:791.

• Nowinski WL, A Thirunavuukarasuu, Volkau I, Runge VM, Salamon N, Salamon G: Interactive atlas of cerebral vasculature. Program 92 Radiological Society of North America Scientific Assembly and Annual Meeting Program 2006, Chicago, USA, 25 November – 1 December 2006:884.

• Nowinski WL, Qian G, Bhanu Prakash KN, Volkau I, Bilello M, Beauchamp NJ: A CAD system for stroke MR and CT. Program 92 Radiological Society of North America Scientific Assembly and Annual Meeting Program 2006, Chicago, USA, 25 November – 1 December 2006:789.

• Ivanov N, Parimal AS, Nowinski WL: A warping tool based on modified radial basis functions for atlas-assisted interpretation of normal and pathological brain scans. Program 92 Radiological Society of North America Scientific Assembly and Annual Meeting Program 2006, Chicago, USA, 25 November – 1 December 2006:784.

• Siddiqui KM, Teistler M, Musk AE, Juluru K, Safdar NM: Comparing Radiologists Interpretation Process: Quantitative analysis using audit logs. Program 92 Radiological Society of North America Scientific Assembly and Annual Meeting Program 2006, Chicago, USA, 25 November – 1 December 2006.

• Nowinski WL, Qian G, Leong WK, Liu J, Kazmierski R, Urbanik A: A Stroke CAD in the ER. 93 Radiological Society of North America Scientific Assembly and Annual Meeting Program 2007, Chicago, USA, 25-30 November 2007:837.

• Nowinski WL, Thirunavuukarasuu A, Volkau I, Marchenko Y, Puspitasari F, Aminah B, Nowinska NG, Blazejewska A, Knopp MV, Runge VM: A 3D interactive atlas of cerebral arteries from 7T. 94 Radiological Society of North America Scientific Assembly and Annual Meeting, Chicago, USA, November 30 – December 5, 2008: 985.

• Nowinski WL, Guoyu Q, Beauchamp NJ, Urbanik A, Liebeskind D, Nighoghossian N, Bhanu Prakash KN, Volkau I, Huang S, Gupta V, Puspitasari F, Hu J, Liu J, Chrzan R, Marcos A, Berthezene Y, Hermier M, Froment JC, Seet CS: A CAD system for ischemic stroke supporting multiple infarct and penumbra definitions and time series acquisitions. 94 Radiological Society of

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North America Scientific Assembly and Annual Meeting, Chicago, USA, November 30 – December 5, 2008: 904.

• Marchenko Y, Volkau I, Puspitasari F, Kulish V, Nowinski WL: Vascular Editor: a tool to create 3D vascular models from MRA/CTA scans for education and interventional procedure. 94 Radiological Society of North America Scientific Assembly and Annual Meeting, Chicago, USA, November 30 – December 5, 2008: 910.

• Nowinski WL, Beauchamp NJ, Bhanu Prakash KN, Liu J, Shibata DK, Gupta V, Huang S, Hu J: Automatic white matter, ventricle, and stroke volumetric analysis of brain MRI multimodal scans useful for epidemiologic studies and in identifying individual risk for future stroke and dementia. 94 Radiological Society of North America Scientific Assembly and Annual Meeting, Chicago, USA, November 30 – December 5, 2008:910.

• Nowinski WL, Qian GY, Bhanu Prakash KN, Volkau I, Leong WK, Huang S, Ananthasumbramaniam A, Liu J, Hu J, Gupta V, Marcos A, Nighoghossian N, Berthezene Y, Hermier M, Froment JC, Seet CS, Kazmierski R, Ambrosius W, Urbanik A, Chrzan R, Beauchamp NJ Jr. A CAD system for acute ischemic stroke. Abstracts of the 6th World Stroke Congress 24-27 September 2008, Vienna Austria, Vol 3, Suppl 1: 288-289.

• Nowinski WL, Thirunavuukarasuu A, Volkau I, Marchenko Y, Aminah B, Puspitasari F, Runge VM: A three-dimensional interactive atlas of cerebral arterial variants. Proc. 46th Annual Meeting of American Society of Neuroradiology ASNR 2008:426.

Accepted:

• Nowinski WL, Chua BC, Marchenko Y, Volkau I, Qian GY, Puspitasari F, Nowinska GA, Huang S, Liu J, Lee LC, Knopp MV, Runge VM: A 3D interactive atlas of cerebral vasculature and structure from 3T and 7T. 47th Annual Meeting of American Society of Neuroradiology ASNR 2009, Vancouver, BC, Canada, 16 – 21 May 2009.

• Nowinski WL, Chua BC, Volkau I, Puspitasari F, Marchenko Y, Runge VM, Knopp MV: Deep brain stimulation: Simulation and assessment of vascular damage using 7T scans. WSSFN 15th Quadrennial Meeting, Toronto, Canada, 24-27 May 2009.

Book chapters Published:

• Miller K, Nowinski WL: Modeling of brain mechanical properties for computer-integrated medicine. In: Springer Tracts in Advanced Robotics (Eds. Dario P, Chatila R), Springer, Berlin, 2005:125–134.

• Nowinski WL: Human brain atlases in education, research and clinical application. Complex Medical Engineering, Springer-Verlag, Tokyo, 2006:335-349.

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• Nowinski WL, Qian G, Bhanu Prakash KN, Volkau I, Leong WK, Huang S, Ananthasubramaniam A, Liu J, Ng TT, Gupta V. Stroke Suite: CAD systems for acute ischemic stroke, hemorrhagic stroke, and stroke in ER. (Eds. Gao X, Muller H, Loomers M, Comley R, Luo S) Medical Imaging and Informatics, Lecture Notes in Computer Science, Springer Volume 4987/2008: 377-386.

Accepted

• Nowinski WL: Anatomical and probabilistic functional atlases in stereotactic and functional neurosurgery. (Eds. Lozano A, Gildenberg P, Tasker R) Textbook of Stereotactic and Functional Neurosurgery 2009, Springer, to be in print June 2009.

Lab of Bioimaging Probe Development Journal papers Published:

• Synthesis and anticancer activity studies of cyclopamine derivatives, Zhang, J.; Garrossian, M.; Gardner, D.; Garrossian, A.; Chang, Y. T.; Kim, Y. K.; Chang, C. W. T. Bioorg. Med. Chem. Lett. 2008, 18, 1359-1363.

• Discovery of heparin chemosensors through diversity oriented fluorescence library approach, Wang, S.; Chang, Y. T.* Chem. Commun. 2008, 1173-1175. Highlighted at “Blood sensor for safer surgery, Chemical Biology (RSC), 2008 (January 10)”

• Small-molecule fluorophores to detect cell-state switching in the context of high-throughput screening, Wagner, B. K.; Carrinski, H. A.; Ahn, Y. H.; Kim, Y. K.; Gilbert, T. J.; Fomina, D. A.; Schreiber, S. L.; Chang, Y. T.; Clemons, P. A. J. Am. Chem. Soc. 2008, 130, 4208-4209.

• Divergent syntheses of all stereoisomers of phytosphingosine and their use in the construction of a ceramide library, Park, J. J.; Li, Q.; Diaz, K.; Chang, Y. T.; Chung, S. K. Bioorg. Chem. 2008, 36, 220-228.

• Forward chemical genetics, Chang, Y. T. Wiley Encyclopedia of Chemical Biology, 2008 (March 14), doi: 10.1002/9780470048672.wecb178.

• A selective human serum albumin sensor from the screening of a fluorescent rosamine library, Ahn, Y. H.; Lee, J. S.; Chang, Y. T. J. Comb. Chem. 2008, 10, 376-380.

• Diversity oriented fluorescence library approach (DOFLA) to the discovery of chymotrypsin sensor, Wang, S.; Kim, Y. K.; Chang, Y. T. J. Comb. Chem. 2008, 10, 460-465.

In press:

• Diversity oriented fluorescence library approach (DOFLA) for novel sensor development, Wang, S.; Chang, Y. T. in “Combinatorial methods for chemical

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and biological sensors”, pp xxx-xxx, Ed. R. A. Potyrailo and V. M. Mirsky), Springer, 2009.

• Machine vision-assisted analysis of structure-localization relationships in a combinatorial library of prospective bioimaging probes, Shedden, K.; Li, Q.; Liu F.; Chang, Y. T.; Rosania, G. Cytometry, 2009, in press.

• Diversity-Oriented Fluorescence Library Approach for Discovery of Sensors and Probe, Lee, J. S.; Kim, Y. K.; Vendrell, M.; Chang, Y. T. Mol. Biosyst. 2009, in press.

Submitted • Synthesis of Bodipy Library and its Application to Live Cell Glucagon Imaging

Probe, Lee, J. S.; Kang, N. Y.; Kim, Y. K.; Samanta, A.; Feng, S.; Kim, H. K.; Park, J. H.; Chang, Y. T. J. Am. Chem. Soc. 2009

• Bodipy-diacrylic acids for site-selective covalent labeling of cell surface proteins, Ahn, Y. H.; Kang, N. Y.; Chang, Y. T. J. Am. Chem. Soc. 2009

• Synthesis and cellular uptake properties of guanidine-containing molecular transporters built on sucrose scaffold, Lee, W. S.; Im, C. N.; Teng, Q. Y.; Chang, Y. T.; Kim, D. C.; Kim, K. T.; Chung, S. K. Mol. Biosys. 2009

• Synthesis and cellular uptake properties of guanidine-containing molecular transporters built on inositol scaffolds, Ghosh, S. C.; Kim, B.; Im, J.; Im, C. N.; Chang, Y. T.; Kim, W.; Kim, K. T.; Chung, S. K. Angew. Chem., Int. Ed. Engl. 2009

Conference Abstracts Published:

• Colorful chemical genetics, Chang, Y. T. Chemical Genomics Symposium, Daejeon, Korea, October 11, 2007 (invited).

• High Throughput Biosensor development using fluorescence library approach, Chang, Y. T. 100th Korean Chemical Society, EXCO Daegu, Korea, October 18-19, 2007 (invited).

• Diversity Oriented Fluorescence Library Approach (DOFLA) for novel bioimaging probe development, Chang, Y. T. Science & Technology FEST 08, Biopolis, Singapore, Jan 30-Feb 1, 2008 (invited).

• Imaging probe development for in vitro, in vivo and clinical applications with DOFLA and ImageXpress micro, Chang Y. T. Total solutions for cellular imaging forum, Grand Copthorne waterfront conference centre, Singapore, February 18, 2008 (invited).

• Colorful Chemical Genetics, Chang, Y. T. World Molecular Imaging Congress, Nice, France, September 10-13, 2008.

• Colorful Chemical Genetics, Chang, Y. T. The 1st RIKEN Chemical Biology Department international symposium, Atami, Japan, September 25-26, 2008 (invited).

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• Colorful chemical genetic approach to diagnosis and treatment of neurodegenerative diseases, Chang, Y. T. 102nd Korean Chemical Society, ICC Jeju, Korea, October 16-17, 2008 (invited).

• Colorful Chemical Genetics, Chang, Y. T. International symposium of Oral Cancer and Cancer Prevention, Yonsei Univ., Seoul, Korea, October 23, 2008 (invited).

• Colorful Chemical Genetics, Chang, Y. Y. The HUGO workshops in genomic sciences: High Content Cellular screening (HCCS), Singapore, November 12-14, 2008 (invited).

• Colorful Chemical Genetics, Chang, Y. Y. The 5th Singapore-China Collaborative and Cooperative Chemistry Symposium (SCCCCS-5), Guangzhou, China, November 15-17, 2008.

• Colorful Chemical Genetics, Chang, Y. Y. Biochemistry and Molecular Biology (BMB 2008), Kobe, Japan, December 11, 2008 (invited).

• Colorful Chemical Genetics, Chang, Y. Y. The 2nd Singapore-Australia Collaborative and Cooperative Chemistry Symposium (SAuCCCS-2), University of Queensland, Brisbane, Australia, December 15-16, 2008.

• Colorful Chemical Genetics, Chang, Y. T. Zing Medicinal Chemistry Conference, Ocean Maya Hotel, Playa Del Carmen, Mexico, February 1-4, 2009.

Bio-optical Imaging Group Journal papers Published:

• Chin WW, Thong PSP, Lau WK, Bhuvaneswari R, Soo KC, Heng PW, Olivo M. Fluorescence imaging and spectroscopy of the photosensitizer chlorine6- polyvinylpyrrolidone for cancer tissue differentiation. BMC Medical Imaging, 8; 9(1): 1, 2009.

• Y Xu, J Singh, C S Premachandran, A Khairyanto, KW S Chen, N Chen, C J R Sheppard and Olivo M and Design and development of a 3D scanningMEMS OCT probe using a novel SiOB package assembly. J of Micromechanics and Microengineering. 18 (125005): 1-8, 2008.

• J Singh, J H S Teo, Y Xu,C S Premachandran, N Chen, R Kotlanka, M Olivo and C J R Sheppard. A two axes scanning SOI MEMS micromirror for endoscopic bioimaging. J of Micromechanics and Microengineering. 18(025001): 1-9, 2008.

• James Chen Yong Kah, Tzu Hao Chow, Beng Koon Ng, Sirajudeen Gulam Razul, Malini Olivo and Colin James Richard Sheppard. Concentration dependence of gold nanoshells on the enhancement of optical coherence tomography images: A quantitative study. Applied Optics. 48(10), 2009 (e pub).

• James Chen Yong Kah, Rachel Cheng Yi Wan, Ker Yi Wong, Subodh Mhaisalkar, Colin James Richard Sheppard, Malini Olivo, Combinational treatment of photothermal therapy using gold nanoshells with conventional photodynamic therapy to improve treatment efficacy: an in vitro study. Lasers Surg Med. 40(8): 584-589, 2008.

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• Kah JC, Wong KY, Neoh KG, Song JH, Fu JW, Mhaisalkar S, Olivo M, Sheppard CJ. Critical parameters in the pegylation of gold nanoshells for biomedical applications: An in vitro macrophage study. J Drug Target. 2008 Nov 22:1.

• Kiang-Wei Kho; Zhu Mei Qing; Ze-Xiang Shen; Iman B. Ahmad; S. C. Lim; Subodh Mhaisalkar; Timothy J. White; Frank Watt; Kee Chee Soo; Malini Olivo, “Polymer-based microfluidics with surface-enhanced Raman-spectroscopy-active periodic metal nanostructures for biofluid analysis”, Journal of Biomedical Optics 13(05), 054026, Sept 2008.

• James C. Y. Kah, Weber, K.O. Lau Phuay-Hoon Tan, Colin J. R. Sheppard, Malini C. Olivo. Endoscopic Image Analysis of Photosensitizer Fluorescence as a Promising Noninvasive Approach for Pathological Grading of Bladder Cancer In Situ. J. of Biomedical Optics, 13(5): 054022, 2008.

• JCY Kah, CJR Sheppard and M Olivo. Synthesis of gold nanoshells using precursor seed particles prepared from a deposition-precipitation process. Gold Bulletin, 41(1): 23-36, 2008.

• Napphawan Phonthammachai, James CY Kah, Guo Jun, Colin JR Sheppard, Malini C Olivo, Subhodh G Mhaisalkar, Timothy J White. Synthesis of Contiguous Silica-Gold Core-Shell Structures: Critical parameters and processes. Langmuir 24(9): 5109-5112, 2008.

• Ramaswamy Bhuvaneswari, Yik Yuen Gan, Sasidharan Swarnalatha Lucky, William Wei Lim Chin, Mohamed Ali-Seyed, Khee Chee Soo and Malini Olivo. Molecular profiling of angiogenesis in hypericin mediated photodynamic therapy. Molecular Cancer, 2008 Jun 13; 7(1): 56.

• William Wei Lim Chin, Paul Wan Sia Heng, Pei Li Lim, Weber Kam On Lau, Malini Olivo. Membrane transport enhancement of chlorine e6-polyvinylpyrrolidone and its photodynamic efficacy on the chick chorioallantoic tumor model. Journal of Biophotonics, 1(5), 395–407, 2008.

• Patricia SP Thong, Malini Olivo, Kiang-Wei Kho, Ramaswamy Bhuvaneswari, William WL Chin, Kong-Wee Ong, Khee Chee Soo. Immune Response against Angiosarcoma following Lower Fluence Rate Clinical Photodynamic Therapy. Journal of Enivronmental Pathology, Toxicology and Oncology. 27(1): 43-50, 2008.

• Constance Lay Lay Saw, Paul Wan Sia Heng, Malini Olivo. Potentiation of the Photodynamic Action of Hypericin. Journal of Environmental Pathology, Toxicology and Oncology, 27(1): 33-42, 2008.

• James KC, Olivo MC, Caroline Lee SG, Sheppard CJR. Molecular contrast of EGFR expression using gold nanoparticles as a reflectance-based imaging probe. Mol Cell Probes. 22(1): 14-23, 2008.

• William Wei Lim Chin, Paul Wan Sia Heng, Patricia Soo Ping Thong, Ramaswamy Bhuvaneswari, Werner Hirt, Sebastian Kuenzel, Khee Chee Soo, Malini Olivo. Improved formulation of photosensitizer chlorin e6–polyvinylpyrrolidone for fluorescence diagnostic imaging and photodynamic therapy of human cancer. Eur. J. of Pharmaceutics and Biopharmaceutics. E pub ahead of print, 2008.

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• Cheong Lee Sing, Lin Feng, Seah Hock Soon, Qian Kemao, Zhao Feng, Patricia SP Thong, Soo Khee Chee, Malini Olivo, Kung Sun-Yuan, Embedded Computing for Fluorescence Confocal Endomicroscopy Imaging, Journal of Signal Processing Systems, Special Issue on Biomedical Imaging, 2008.

In press:

• James Chen Yong Kah, Tzu Hao Chow, Beng Koon Ng, Sirajudeen Gulam Razul, Malini Olivo and Colin James Richard Sheppard. Quantitative analysis of concentration variations on gold nanoshells enhanced OCT imaging. Applied Optics. 2009, in press.

• Kah JCY, Mhaisalkar S, Sheppard CJR, Olivo M. Selectivity of bioconjugated gold nanoshells for optical contrast and molecular mapping of biomarkers in cancer cells with reflectance-based imaging. Int J. Bioimaging, in press, 2009.

• James Chen Yong Kah,Tzu Hao Chow, Subodh Mhaisalkar, Malini Olivo, Colin James Richard Sheppard, Backscattering response of gold nanoshells as an appropriate optical contrast parameter in reflectance-based imaging applications. Optics Communication. 2009, in press.

• James Chen Yong Kah, Kiang-Wei Kho, Tzu-Hao Chow, Colin James Richard Sheppard, Ze-Xiang Shen, Kee-Chee Soo, Malini Olivo. Photodetection in the non-fluorescent regime with gold nanostructures. Lasers in Surgery and Medicine, in press, 2009.

• Bhuvaneswari R, Gan YY, Soo KC and Olivo M. “Effect of Photodynamic therapy on tumor angiogenesis.” Cellular and Molecular life sciences, in press, 2009.

• Kiang Wei Kho, ZeXiang Shen, Frank Wat and Malini Olivo, "Electromagnetic Analysis of Field Enhancement on a Smooth Metal Surface with Spheroid Dielectric Nano-Cavity", Physical Review, 2009 (in press).

• Liu Jun, Saw Lay Lay, Olivo M and Thorsten Wohland. The study of interaction of hypericin and its pharmaceutical preparation by fluorescence techniques". J of Biomedical Optics, in press, 2009

Conference Abstracts Published:

• Chin WW, Heng PW, Lau WK, Lim PL, Bhuvaneswari R, Thong PSP, Olivo M. Fluorescence kinetics and drug transport of chlorine e6 – polyvinylpyrrolidone for photodynamic applications of urological cancer. 34th American Society for Photobiology (ASP) 2008, Burlingame, CA, June 20 – 25, 2008.

• Patricia S.P. Thong, William W.L. Chin, Ramaswamy Bhuvaneswari, Kiang-Wei Kho, Kent Mancer, Malini Olivo, Khee-Chee Soo. Fluorescence Diagnostic Imaging of Lesions in the Human Oral Cavity using Hypericin. 34th American Society for Photobiology (ASP) 2008, Burlingame, CA, June 20 – 25, 2008.

• Ramaswamy Bhuvaneswari, Yik Yuen Gan, Sasidharan Swarnalatha Lucky, William Wei Lim Chin, Mohamed Ali-Seyed, Khee Chee Soo and Malini Olivo.

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Evaluation of angiogenic markers in vascular and cellular mediated photodynamic therapy using hypericin. 34th American Society for Photobiology (ASP) 2008, Burlingame, CA, June 20 – 25, 2008.

• Chin WW, Thong PSP, Bhuvaneswari R, KC Soo, Heng PW, Olivo M.Chlorin e6-polyvinylpyrrolidone induced fluorescence endoscopy and spectroscopy for in vivo cancer diagnostics. Optics Within Life Sciences –10 Biophotonics Asia, 2 – 4 July, 2008, Singapore.

• Patricia S.P. Thong, Cheong Lee Sing, Malini Olivo, Lin Feng, Seah Hock Soon, Qian Kemao, Khee-Chee Soo. Development of a Real-Time Image Processing and Analysis System for Real-Time Fluorescence Diagnostic Imaging of the Oral Cavity in the Clinic. Optics Within Life Sciences –10 Biophotonics Asia, 2 – 4 July, 2008, Singapore.

• Ramaswamy Bhuvaneswari, Yik Yuen Gan, Patricia SP Thong, William Wei Lim Chin, Khee Chee Soo, Malini Olivo. Targeted Therapy of Bladder Carcinoma by Combining Photodynamic Therapy and Angiogenesis Inhibitors. Optics Within Life Sciences –10 Biophotonics Asia, 2 – 4 July, 2008, Singapore.

• Y. Xu, J. Singh, T. H. S. Jason, K. Ramakrishna, C. S. Premachandran, C. W. S. Kelvin, C. T. Kuan, N. Chen, M. C. Olivo, C. J. R. Sheppard, MEMS based non rotatory circumferential scanning optical probe for endoscopic optical coherence tomography, SPIE European Conferences of Biomedical Optics - Optical Coherence Tomography and Coherence Techniques 17 to 21 Jun 2007, Munich, Germany, published in Proceedings of SPE -OSA Biomedical Optics 1605 to 7422 Vol. 6627, 15-1 to 15-11 (2007).

• C.S. Premachandran, K.C.W. Sheng, J. Singh, T.H.S. Jason, X. Yinghsun, N. Chen, C. JR. Sheppard, M. Olivo, Design, fabrication, and assembly of an optical biosensor probe package for OCT (optical coherence tomography) application, 2007 Electronic Components and Technology Conference, 1556-1560 (2007).

• Kiang Wei Kho, Kristin Zhu Mei Qing, Ze Xiang Shen, Iman Binte Ahmad, Samanta Sing Chin Lim, Subodh Mhaisalkar, Timothy John White, Frank Watt, Kee Chee Soo, Malini Olivo, “A Polymer-based Microfluidics with SERS-active Periodic Metal Nano-structures for Bio-fluid Analysis”, Optics Within Life Sciences –10 Biophotonics Asia, 2–4 July, 2008, Singapore.

• K.W. Kho, A. Iman, Z.Y. Koh, S. Madhavi, Z.X. Shen, C. Sheppard, W. Frank, S.G. Mhaisalkar, J.W. Timothy, M. Olivo, “Surface Enhanced Raman Spectroscopy using a smooth planar metal surface with embedded nano-cavities”, XXIst International Conference on Raman Spectroscopy, Brunel University, London, UK, 17th – 22nd Aug. 2008.

• K.W. Kho, Z.M. Qing, Z.X. Shen, A. Iman, S.C. Lim, S.G. Mhaisalkan, W. Frank, S.G. Mhaisalkar, K.C. Soo, M. Olivo, “A report on a SERS-based polymer microfluidics incorporated with in-channel periodic metal nano-structures”, XXIst International Conference on Raman Spectroscopy, Brunel University, London, UK, 17th – 22nd Aug. 2008.

• Photodetection of Cancer with Fluorescence and Non-Fluorescent. Nano-Gold IEEE Photonics Global @ Singapore. 8-11 Dec 2008 (invited talk)

• Photodetection of Human Cancer With Gold Nanostructures, Singapore Nanomedicine Workshop 2008 (invited talk)

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• Nanophotonics Initiatives in cancer detection and therapy, Ontario Cancer Institute Toronto, Canada November 2008 (invited talk)

• MEMS optical probe for cancer diagnostics using optical coherence tomography. Inaugural A*Star scientific conference, November 2008 (invited talk)

Book Published:

• Feng Lin, Malini Olivo, Sun-Yuan Kung Ed. Biomedical Imaging. Springer US, 2008.