malaria, its pathology, epidemiology and clinical manifestations
TRANSCRIPT
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MALARIAPresented By
JESNA BABY
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Definition It is defined as a mosquito borne
infectious disease of human caused by parasitic protozon of the genus plasmodium transmitted via a bite form an infected female anopheles mosquito.
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By protozoan parasites of the genus protoz plasmodium.
4 species Plasmodium falciparum
Plasmodium vivax Plasmodium ovale
Plasmodium malariaePeople get malaria by bittening of infected
female Anopheloes mosquito.
ETIOLOGY
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An estimated 300 million cases of malaria occur each year.
Annually accounting for 1.5 to 2.7 million death
Most of the death are due to infection with plasmodium falciparum & occur among children & pregnant women in the developing world , especially sub- Saharan Africa.
EPIDEMIOLOGY
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PATHOPHYSIOLOGY
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Vector transmission – Bite by infective female anopheles mosquitoes
Direct transmission Blood transfusion The use of contaminated needle and
syringe Organ transplant Congential transmission mother to new born
ROUTE OF TRANSMISSION
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Fever Shaking chills Headache Tiredness Nausea Vomiting Diarrhea It may cause anaemia and jaundice
SIGNS AND SYMPTOMS
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Environmental factor A warm humid climate temperature
between 16℃ and 40℃ and abundant rainfall have anopheles mosquitoes
Vegetation nearby to provide shade for the mosquito to hide the day and digest the blood meal from the night before
RISK FACTORS
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Human factor Poor water supply and sanitation
People working in the field and in irrigation system near or on lakes and reservoris
Migrates moving into malarial areas clearing land looking for work refuges
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PREVENTION Preventing mosquito accessing egg laying
habitats by management& modification
Coverivg ,emptying&cleaning of domestic water storage containers
apply insecticides to water storage outdoor containers
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Using personal household protection such as window screen,long sleeved clothes,coils,vaporizers
Massage exposed body parts with insect repellent,
Spread awareness about dengue mosquito
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Prevent patient from being bitten by mosquitoes
Breed small mosquito eating fishes in artificial pond to eradicate mosquito larvae
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Blood film examination
o Thick blood film Used for detecting malaria larger volume
of blood is examined allowing detection of even low levels of parasitaemia.
DIAGNOSIS
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Thin blood film
o Gives more information about the parasite morphology and therefore is used to identify the particular infecting species of plasmodium
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Rapid diagnostic tests
PCR based techniques
Fluorescent techniques
Serologic tests
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Quinine
Chloroquine
Mefloquine
Antibiotic (eg: doxocycline, dindamycin,azithramycin)
TREATMENT
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THANK YOU