mancozeb toxicology info

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Mancozeb - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatoryinformation

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Chemical IDIdentifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of

all products containing this chemical and a list of the top crops this pesticide is used on in California.

Poisoning SymptomsSigns and symptoms of poisoning, first aid, and links to treatment information for this chemical.

ToxicityLink to information on toxicity to humans, including carcinogenicity, reproductive and developmental

toxicity, neurotoxicity, and acute toxicity.

RegulatoryLinks to world-wide registration status as well as regulatory information for the U.S. and California.

WaterWater quality standards and physical properties affecting water contamination potential.

EcotoxicityToxicity to aquatic organisms.

Related ChemsList of chemicals in the same family, including breakdown products, salts, esters, isomers, and other

derivatives.

Chemical Identification and Use for Mancozeb

Basic Identification Information About This Chemical

Chemical Name: Mancozeb

CAS Number: 8018-01-7

U.S. EPA PC Code: 014504

CA DPR Chem Code: 211

Molecular Weight: 332.71

Molecular Structure:

Use Type: Fungicide

Chem Class: Dithiocarbamate , Inorganic-Zinc

View Related Chemicals

Additional Resources About This Chemical Class and Use Type

See the Global Pesticide Resources page for many additional links.

Mancozeb - toxicity, ecological toxicity and regulatory information http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC35080

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Historical Use of this Chemical

Top five crops and sites for this pesticide in California

Onions Pears Landscape Table and Raisin Grapes Potatoes

View All Crops and Sites

Other Names for this ChemicalAbout Chemical Synonyms

00211 (CA DPR Chem Code Text) , 00211 (CA DPR Chem Code) , 014504 (US EPA PC Code Text) , 14504 (US EPA PC Code) , 211 (CA DPR Chem

Code) , 211 (CA DPR Chem Code) , 8018-01-7 (CAS number) , 8018017 , 8018017 (CAS number without hyphens) , Carbamic acid,

ethylenebis{dithio-},manganese zinc complex , Carbamic acid, ethylenebis{dithio-},manganese zinc complex (8CI) , Carbamodithioic acid,

1,2-ethanediylbis-, manganous zinc salt , Dithane (mancozeb) M-45 technical premix , Dithane M-45 , EBDC, as a coordination product with Mn and Zn

, Fore , Mancozeb , Mancozeb , Mancozeb - Zn , Mancozeb Zinc , Mancozebe , Maneb with Zinc , Manganese, {{1,2-ethanediylbis{carbamodithioato}}

(2-)}-, mixt. with {{1,2-ethanediylbis{carbamodithioato}}(2-)}Zinc , Mankoceb , mankozeb , Manzate 200 , Manzeb , Manzin 80 , Mn-Zn Ethylene

bisdithiocarbamate , Nemispor , Pace fungicide (014504+113501) , Penncozeb , Policar MZ , Policar S , Vondozeb Plus , Zinc ion and manganese

ethylenebisdithiocarbamate 80%; a coordination product of manganese 16%, zinc 2%, and ethylenebisdithioca , Zinc ion and manganese

ethylenebisdithiocarbamate, coordination product , Zinc manganese ethylenebisdithiocarbamate

Products Containing This Chemical

Current and historic U.S. registered products

View U.S. Products All Products Currently Registered Products

Signs and Symptoms of Mancozeb Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.If the victim has collapsed or is unconscious, call 911.

Mancozeb is a Ethylenebisdithiocarbamate (EBDC) compound. Report a Poisoning

Symptoms of Poisoning with Ethylenebisdithiocarbamate (EBDC) Compounds Find Products Containing this Chemical

- Irritation of skin, eyes and respiratory tract.

- Skin sensitization.

- Chronic skin disease has been observed in occupationally exposed workers.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 15.

Treatment for Ethylenebisdithiocarbamate (EBDC) Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 15, pages 144 and 139.

Symptoms of Mancozeb Exposure from the International Chemical SafetyCards (ICSC)

Report a Poisoning

View full ICSC Cards: English Español Française Chinese Dutch Finnish German Hungarian Japanese Swahili Thai Urdu

NOTE! PREVENT DISPERSION OF DUST! AVOID ALL CONTACT!

Route of Exposure Symptoms First Aid

Inhalation Cough. Sore throat. Fresh air rest. Refer for medical attention.

SkinRedness.

Remove contaminated clothes. Rinse and then wash skin

with water and soap.


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EyesRedness. Pain.

First rinse with plenty of water for several minutes (remove

contact lenses if easily possible) then take to a doctor.

IngestionDiarrhoea. Nausea. Vomiting.

Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS

PERSONS!).

Notes for ICSC Information

Maneb a related substance may cause also other effects after long-term exposure. If the substance is formulated with solvent(s) also consult the

card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Aimcozeb Crittox

MZ Dithane 945 Dithane M-45 Fore Karamate Mancozin Manzate 200 Manzin Nemispor Penncozeb Phytox MZ Riozeb Vondozeb Plus are trade

names. See ICSC1148 2-Mercaptoimidazoline a contaminant and breakdown product ICSC0173 Maneb and ICSC0350 Zineb.

Toxicity Information for Mancozeb

Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor

Chemical 1

Acute

Toxicity 2

Carcinogen Cholinesterase

Inhibitor

Ground

Water Contaminant

Developmental or

Reproductive Toxin

Endocrine

Disruptor

Not Acutely Toxic No Potential Suspected

Indicates high toxicity in the given

toxicological category.

Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from

scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical

detail page.

1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known

groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs

are not yet considered PAN Bad Actor chemicals.

2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute

toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Additional Resources about the Toxicity of this Chemical

See the Global Pesticide Resources page for many additional links.

Detailed Toxicity Information This Chemical Parent Chemical

Acute Toxicity 2 Mancozeb Ethylene thiourea

WHO Acute Hazard

TRI Acute Hazard

Material Safety Data Sheets

Acute rating from U.S. EPA product label

U.S. NTP Acute Toxicity Studies

View Studies

Cholinesterase Inhibitor

U, Unlikely to be Hazardous

Not Listed

Not Available

No Consensus Value

No NTP Studies

No

Not Listed

Not Listed

Not Available

No Consensus Value

Slightly Toxic

No

2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute

toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.


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Cancer Information Mancozeb Ethylene thiourea

IARC Carcinogens

U.S. NTP Carcinogens

California Prop 65 Known Carcinogens

U.S. EPA Carcinogens

TRI Carcinogen

Not Listed

Not Listed

Yes

B2, Probable

Yes

3, Unclassifiable

Reasonably Anticipated

Yes

B2, Probable

Not Listed

Endocrine Disruption Mancozeb Ethylene thiourea

Illinois EPA list

Keith list

Colborn list

Benbrook list

Danish Inert list

EU list

Probable

Yes

Yes

Yes

Not listed

Yes

Not listed

Not listed

Yes

Not listed

Not listed

Yes

Reproductive and Developmental Toxicity Mancozeb Ethylene thiourea

CA Prop 65 Developmental Toxin

U.S. TRI Developmental Toxin

CA Prop 65 Female Reproductive Toxin

CA Prop 65 Male Reproductive Toxin

U.S. TRI Reproductive Toxin

Not Listed

Yes

Not Listed

Not Listed

Yes

Yes

Not Listed

Not Listed

Not Listed

Not Listed

Chemicals of Special Concern Mancozeb Ethylene thiourea

PAN Bad Actors

PAN Dirty Dozen list

Yes

Not Listed

Yes

Not Listed

Water Pollution Potential and Criteria for Mancozeb

Water Pollution Potential This Chemical Parent Chemical

Mancozeb Ethylene thiourea

PAN Ground Water Contaminant Rating Potential Insufficient Data

Physical Property Data Related to Water Contamination Potential

Water Solubility (Avg, mg/L)

Adsorption Coefficient (Koc)

Hydrolysis Half-life (Avg, Days)

Aerobic Soil Half-life (Avg, Days)

Anaerobic Soil Half-life (Avg, Days)

6.20

6,000

166.0

2.00

-

Sorry, no water quality standards or criteria have been established for this chemical by the U.S. or Canadian governments; however, there may

be criteria established for related chemicals.


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Regulatory Information for Mancozeb

International Regulatory Status This Chemical Parent Chemical

Registration in Selected Countries Registration in Selected Countries:

Mancozeb

Registration for Selected Countries:

Ethylene thiourea

UNEP Persistent Organic Pollutant (POP)

UNEP Prior Informed Consent Chemical (PIC)

WHO Obsolete Pesticide

Not Listed

Not Listed

Not Listed

Not Listed

Not Listed

Not Listed

U.S. and California Regulatory Status

U.S. EPA Registered

U.S. EPA Hazardous Air Pollutant

U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered

CA Groundwater Contaminant

CA Toxic Air Contaminant

Yes

Yes

No

Yes

Not Listed

HAPTAC, Pesti

No

Yes

No

No

Not Listed

HAPTAC, Indus

Maximum Tolerance and Residue Levels

Codex Alimentarius

(UN FAO Maximum Residue Limits)

U.S. Maximum Tolerance Levels

European Union Maximum Residue Levels

Go to web site

Go to web site

Go to web site

Ecotoxicity for Mancozeb

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on

underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group

Organism Group Effects Noted

Amphibians Development, Growth, Morphology, Mortality, Population

FishBiochemistry, Cell(s), Development, Enzyme(s), Feeding Behavior, Growth, Histology, Injury, Mortality, No Effect Coded,

Physiology, Reproduction

Fungi Development, Population, Reproduction

Molluscs Intoxication

NematodesandFlatwormsEnzyme(s)

Phytoplankton Growth, Mortality, Physiology, Population

Zooplankton Intoxication, Mortality

~ Un-Assigned Behavior, Mortality, Physiology, Population, Reproduction

View All Aquatic Ecotoxicity Studies and References


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Summary of Acute Toxicity for Organism Group

Organism Group Average Acute Toxicity Acute Toxicity Range

Amphibians Highly Toxic Moderate to High Toxicity

Fish Moderately Toxic Moderate to High Toxicity

Zooplankton Not Acutely Toxic Not Acutely Toxic to High Toxicity

View All Acute Summaries

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group

Organism Group Average Acute Toxicity Acute Toxicity Range

Honeybees Not AcutelyT Toxic Not AcutelyT Toxic

Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with

honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee

colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.

Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Mancozeb

CAS

Number

Relation Reason Chemical Name Chem Detail Registration Symptoms California Use Chem Use

Type

U.S.

EPA

Reg

PAN

Bad

Actor

96-45-7 Parent P Ethylene thiourea View View View View

Breakdown

product,

Impurity

No Yes

5895-18-1 Related 1, 5aCalcium

ethylenebis(dithiocarbamate)View View View View Microbiocide No Yes

3566-10-7 Related 1, 5aDiammonium


14484-64-1 Related 1, 5a Ferbam View View View View Fungicide Yes Yes

8018-01-7 Related 1, 5a Mancozeb View View View View Fungicide Yes Yes

12427-38-2 Related 1, 5a Maneb View View View View Fungicide Yes Yes

8005-46-7 Related 1, 5a

Maneb and nickel sulfate

hexahydrate (014505 +

050505)

View View View View Fungicide No Yes

9006-42-2 Related 1, 5a Metiram View View View View Fungicide Yes Yes

142-59-6 Related 1, 5a Nabam View View View ViewFungicide,

HerbicideYes Yes

22221-14-3 Related 1, 5aPotassium ammonium


Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.


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Any underlined term with a book icon has additional information.

* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to

a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to

"mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then

marked with an asterisk.

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Citation: Kegley, S.E., Hill, B.R., Orme S., Choi A.H., PAN Pesticide Database, Pesticide Action Network, North America (San Francisco, CA, 2010), http:www.pesticideinfo.org.

© 2000-2010 Pesticide Action Network, North America. All rights reserved.


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mancozeb toxicology info

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