master 2 research fragrances & fine chemistrychemistry.univer.kharkov.ua/./files/presentation...
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MASTER 2 Research MASTER 2 Research Fragrances & Fine ChemistryFragrances & Fine Chemistry
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Nice
Co diploma Co diploma MASTER 2 Chemistry MASTER 2 Chemistry
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Nice
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Nice
Grasse
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Grasse
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11stst SemesterSemesterOctoberOctober--DecemberDecember
MASTER 2 Research MASTER 2 Research Fragrances & Fine ChemistryFragrances & Fine Chemistry
Organic synthesisOrganic synthesis
Fragrance Fragrance ChemistryChemistry
Analytical Analytical chemistrychemistry
Bibliography Bibliography & Project & Project
managementmanagement
English coursesEnglish courses
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11stst SemesterSemesterOctoberOctober--DecemberDecember
MASTER 2 Research MASTER 2 Research Fragrances & Fine ChemistryFragrances & Fine Chemistry
Organic synthesisOrganic synthesis
Fragrance Fragrance ChemistryChemistry
Analytical Analytical chemistrychemistry
Bibliography Bibliography & Project & Project
managementmanagement
English coursesEnglish courses
22ndnd SemesterSemesterJanuaryJanuary--JuneJune Practical activity
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http://www.unice.fr/ecomers/http://www.unice.fr/ecomers/
Host laboratories Host laboratories
http://www.unice.fr/icn/http://www.unice.fr/icn/ http://lpmc.unice.fr/http://lpmc.unice.fr/
LaboratoirePhysique de la Matière Condensée
http://www.cepam.cnrs.fr/http://www.cepam.cnrs.fr/
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http://www.unice.fr/icn/http://www.unice.fr/icn/
Bioactive molecules
Marine Natural ProductsFluorescent Probes
Decorporation
Eco-Friendly Materials and Polymers
Bioinspiration
Catalysis & Fine Chemistry
Fragrance chemistry Origin of Life
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Bioactive molecules
Natural
Synthetic
RNA
Proteins
Induce stress in cancer cells
Selective targeting of cancer stem cells
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Marine Natural Products
Applications: • Pharmaceutical • Environmental (antifoulings)• Cosmetics
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Marine Natural Products
Applications: • Pharmaceutical • Environmental (antifoulings)• Cosmetics
IsolationIsolation
MetabolomeMetabolome
Structural determinationStructural
determination
SynthesisSynthesis
ValorizationValorization
ExtractionExtraction
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Fluorescent Probes
ObjectiveTo understand nucleic acid / protein and nucleic acid / nucleic acid assemblies.
How ?Synthesis of dedicated fluorescent tools for in vitro studies and cell imaging
InternalLabeling
ε ≈ 18,000 M-1.cm-1
Ф ≈ up to 38 %
O
O
O
PO O
O
OHO
S
370 nm 440 nm
540 nm
Br Br N BrR2
R1
Pd-catalyzed monoamination
[12 examples][air-stable cat. syst.]
[practical & gram-scale] [varied-amine tolerance]
NR2
R1 O
AcceptorFunctionalization
R1,R2 = H, aryl & aliphatic
ClickableBioconjugation
Applications
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Decorporation
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Eco-Friendly Materials and Polymers
*Biobased and/or eco-friendly polymers and (nano)composites
*Valorization of : - second generation biomass - co-products from industry and bioraffineries
*Recycling and circular economy
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Eco-Friendly Materials and Polymers
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Bioinspiration
Inspiration from natural surfaces (Animal and vegetal)
Applications for Surface Elaboration :
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Chemistry
Electropolymerization
Surface characterizations
Bioinspiration
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Catalysis & Fine Chemistry
MA + B A B
Sustainable developmentDevelopment of selective methods: C-C, C-O, C-N, C-F…High production, optimization of process
Recyclable catalyst Water-soluble catalystChiral catalyst
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Catalysis & Fine Chemistry
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Fragrance chemistry
O
Mimosa Violet Atlas Cedarwood
Vetiver Frankincense
Characterisation of the odorants of natural raw materials :Chemical and Sensorial Analysis of Volatiles
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Fragrance chemistry
Characterisation of pheromones :Chemical Analysis & Behavioral studies
Murine model : Human model :
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Origin of Life
Myrgorodska, Meinert, Meierhenrich et al.: Angew. Chem. Int. Ed. 54 (2015), 1402
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MASTER 2 Research MASTER 2 Research Fragrances & Fine ChemistryFragrances & Fine Chemistry
CONTACT : CONTACT : [email protected]@unice.fr