material safety data sheet - tousimis.com · nitrile/butadiene rubber ("nitrile" or...

1 © 2018

SAFETY DATA SHEET CATALOG #1051

GLUTARALDEHYDE

Product name: GLUTARALDEHYDE

COMPANY IDENTIFICATION TOUSIMIS RESEARCH CORP. 2211 LEWIS AVENUE ROCKVILLE, MARYLAND 20851 UNITED STATES

Company Contact Information:

301-881-2450

[email protected]

EMERGENCY TELEPHONE NUMBER

24-Hour Emergency Contact: 1-800-222-1222

Hazard classification This material is hazardous under the criteria of the Federal OSHA Hazard Communication Standard 29CFR 1910.1200. Acute toxicity - Category 3 - Oral Acute toxicity - Category 2 - Inhalation Skin corrosion - Category 1 Serious eye damage - Category 1 Respiratory sensitisation - Category 1 Skin sensitisation - Category 1 Specific target organ toxicity - single exposure - Category 3

1. IDENTIFICATION

2. HAZARDS IDENTIFICATION

mailto:%[email protected]

2 CATALOG #1051 GLUTARALDEHYDE © 2018

Label elements Hazard pictograms

Signal word: DANGER!

Hazards Toxic if swallowed. Causes severe skin burns and eye damage. May cause an allergic skin reaction. Fatal if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.

Precautionary statements

Prevention Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. Wash skin thoroughly after handling. Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/ protective clothing/ eye protection/ face protection. Wear respiratory protection.

Response IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. Rinse mouth. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/ Take off immediately all contaminated clothing. Rinse skin with water/ shower. IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/ physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/ physician. If skin irritation or rash occurs: Get medical advice/ attention. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/ physician. Wash contaminated clothing before reuse.

Storage Store in a well-ventilated place. Keep container tightly closed. Store locked up.


Disposal Dispose of contents/ container to an approved waste disposal plant.

Other hazards No data available

Synonyms: Glutaral This product is a substance.

Component CASRN Concentration

Glutaraldehyde 111-30-8 50.0%

Water 7732-18-5 <= 50.0 %

Description of first aid measures

General advice: First Aid responders should pay attention to self-protection and use the recommended protective clothing (chemical resistant gloves, splash protection). If potential for exposure exists refer to Section 8 for specific personal protective equipment.

Inhalation: Move person to fresh air. If person is not breathing, call an emergency responder or ambulance, then give artificial respiration; if by mouth to mouth use rescuer protection (pocket mask etc). Call a poison control center or doctor for treatment advice. If breathing is difficult, oxygen should be administered by qualified personnel.

Skin contact: Take off contaminated clothing. Wash skin with soap and plenty of water for 15-20 minutes. Call a poison control center or doctor for treatment advice. Wash clothing before reuse. Shoes and other leather items which cannot be decontaminated should be disposed of properly. Suitable emergency safety shower facility should be immediately available.

Eye contact: Wash immediately and continuously with flowing water for at least 30 minutes. Remove contact lenses after the first 5 minutes and continue washing. Obtain prompt medical consultation, preferably from an ophthalmologist. Suitable emergency eye wash facility should be immediately available.

Ingestion: If the person is fully alert and cooperative, have the person rinse mouth with plenty of water. In cases of ingestion have the person drink 4 to 10 ounces (120-300 mL) of water. Do not induce vomiting. Do not attempt mouth rinse if the person has respiratory distress, altered mental status, or nausea and vomiting. Call a physician and/or transport to emergency facility immediately. Instantly wash with water and soap and rinse thoroughly.

3. COMPOSITION/INFORMATION ON INGREDIENTS

4. FIRST AID MEASURES


Seek immediate medical advice.

Most important symptoms and effects, both acute and delayed: Aside from the information found under Description of first aid measures (above) and Indication of immediate medical attention and special treatment needed (below), any additional important symptoms and effects are described in Section 11: Toxicology Information.

Indication of any immediate medical attention and special treatment needed

Notes to physician: Maintain adequate ventilation and oxygenation of the patient. May cause respiratory sensitization or asthma-like symptoms. Bronchodilators, expectorants and antitussives may be of help. Glutaraldehyde may transiently worsen reversible airways obstruction including asthma or reactive airways disease. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. Respiratory symptoms, including pulmonary edema, may be delayed. Persons receiving significant exposure should be observed 24-48 hours for signs of respiratory distress. Chemical eye burns may require extended irrigation. Obtain prompt consultation, preferably from an ophthalmologist. If burn is present, treat as any thermal burn, after decontamination. Due to irritant properties, swallowing may result in burns/ulceration of mouth, stomach and lower

gastrointestinal tract with subsequent stricture. Aspiration of vomitus may cause lung injury. Suggest endotracheal/esophageal control if lavage is done. Probable mucosal damage may contraindicate the use of gastric lavage. No specific antidote. Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient. Have the Safety Data Sheet, and if available, the product container or label with you when calling a poison control center or doctor, or going for treatment. Excessive exposure may aggravate preexisting asthma and other respiratory disorders (e.g. emphysema, bronchitis, reactive airways dysfunction syndrome).

Suitable extinguishing media: To extinguish combustible residues of this product use water fog, carbon dioxide, dry chemical or foam.

Unsuitable extinguishing media: None known.

Special hazards arising from the substance or mixture

Hazardous combustion products: Under fire conditions some components of this product may decompose. The smoke may contain unidentified toxic and/or irritating compounds. Combustion products may include and are not limited to: Carbon monoxide. Carbon dioxide.

Unusual Fire and Explosion Hazards: This material will not burn until the water has evaporated. Residue can burn.

Advice for firefighters

Fire Fighting Procedures: Keep people away. Isolate fire and deny unnecessary entry. To extinguish combustible residues of this product use water fog, carbon dioxide, dry chemical or foam. Contain fire water run-off if possible. Fire water run-

5. FIREFIGHTING MEASURES


off, if not contained, may cause environmental damage. Review the "Accidental Release Measures" and the "Ecological Information" sections of this SDS.

Special protective equipment for firefighters: Wear positive-pressure self-contained breathing apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet, coat, trousers, boots, and gloves). Avoid contact with this material during fire fighting operations. If contact is likely, change to full chemical resistant fire fighting clothing with self-contained breathing apparatus. If this is not available, wear full chemical resistant clothing with self-contained breathing apparatus and fight fire from a remote location. For protective equipment in post-fire or non-fire clean-up situations, refer to the relevant sections.

Personal precautions, protective equipment and emergency procedures: Evacuate area. Keep upwind of spill. Ventilate area of leak or spill. Only trained and properly protected personnel must be involved in clean-up operations. Refer to section 7, Handling, for additional precautionary measures. Use appropriate safety equipment. For additional information, refer to Section 8, Exposure Controls and Personal Protection.

Environmental precautions: Prevent from entering into soil, ditches, sewers, waterways and/or groundwater. See Section 12, Ecological Information. Spills or discharge to natural waterways is likely to kill aquatic organisms.

Methods and materials for containment and cleaning up: Avoid making contact with spilled material, glutaraldehyde will be absorbed by most shoes. Always wear the correct protective equipment, consisting of splashproof monogoggles, or both safety glasses with side shields and a wraparound full-face shield, appropriate gloves and protective clothing. A self-contained breathing apparatus or respirator and absorbents may be necessary, depending on the size of the spill and the adequacy of ventilation. Small spills: Wear the correct protective equipment and cover the liquid with absorbent material. Collect and seal the material and the dirt that has absorbed the spilled material in polyethylene bags and place in a drum for transit to an approved disposal site. Rinse away the remaining spilled material with water to reduce odor, and discharge the rinsate into a municipal or industrial sewer. Large spills: In case of nasal and respiratory irritation, vacate the room immediately. Personnel cleaning up should be trained and equipped with a self-contained breathing apparatus, or an officially approved or certified full-face respirator equipped with an organic vapor cartridge, gloves, and clothing impervious to glutaraldehyde, including rubber boots or shoe protection. Deactivate with sodium bisulfite (2-3 parts (by weight) per part of active substance glutaraldehyde), collect the neutralized liquid and place in a drum for transit to an approved disposal site.

6. ACCIDENTAL RELEASE MEASURES


Precautions for safe handling: Do not spray or aerosolize the undiluted form of

the product. Full personal protective equipment (including skin covering and full-face SCBA respirator) is required for dilutions or mixtures of the product used in a spray application.

Keep out of reach of children. Do not get in eyes, on skin, on clothing. Do not swallow. Avoid prolonged or repeated contact with skin. Avoid breathing vapor. Keep container closed. Use with adequate ventilation. Wear goggles, protective clothing and butyl or nitrile gloves. Wash thoroughly with soap and water after handling. Remove contaminated clothing and wash before reuse. See Section 8, EXPOSURE CONTROLS AND PERSONAL PROTECTION.

Conditions for safe storage: Do not store in: Aluminum. Carbon steel. Copper. Mild steel. Iron.

Storage stability

Shelf life: Use within 18 Months

Control parameters Exposure limits are listed below, if they exist.

Component Regulation Type of listing Value/Notation Glutaraldehyde ACGIH C 0.05 ppm

ACGIH C DSEN, RSEN

Exposure controls

Engineering controls: Use engineering controls to maintain airborne level below exposure limit requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, use only with adequate ventilation. Local exhaust ventilation may be necessary for some operations.

Individual protection measures

Eye/face protection: Use chemical goggles. If exposure causes eye discomfort, use a full- face respirator. Use a full-face respirator when material is heated or when aerosols/mists are generated. Eye wash fountain should be located in immediate work area. Skin protection

Hand protection: Use gloves chemically resistant to this material. Examples of preferred glove barrier materials include: Butyl rubber. Examples of acceptable glove barrier materials include: Nitrile/butadiene rubber ("nitrile" or "NBR"). NOTICE: The selection of a specific glove for a particular application and duration of use in a workplace should also take into account all relevant workplace factors such as, but not limited to: Other chemicals which may be handled, physical requirements (cut/puncture protection, dexterity, thermal protection), potential body reactions to glove materials, as well as the instructions/specifications provided by the glove supplier.

7. HANDLING AND STORAGE

8. EXPOSURE CONTROLS/PERSONAL PROTECTION


Other protection: Use protective clothing chemically resistant to this material. Selection of specific items such as face shield, boots, apron, or full body suit will depend on the task. Safety shower should be located in immediate work area. Use chemical protective clothing resistant to this material, when there is any possibility of skin contact. Remove contaminated clothing immediately, wash skin area with soap and water, and launder clothing before reuse or dispose of properly. Items which cannot be decontaminated, such as shoes, belts and watchbands, should be removed and disposed of properly.

Respiratory protection: Atmospheric levels should be maintained below the exposure guideline. When respiratory protection is required for certain operations, use an approved air- purifying respirator. This product is a respiratory irritant. If discomfort is experienced ventilation is not adequate and an approved full face air-purifying respirator is recommended. If vapors are strong enough to be irritating to the nose, or eyes, the OEL is probably being exceeded. Special ventilation or respiratory protection may be required. For operations such as spraying and other conditions such as emergencies where the exposure guideline may be greatly exceeded, use an approved positive-pressure self-contained breathing apparatus. For emergency response or for situations where the atmospheric level is unknown, use an approved positive-pressure self-contained breathing apparatus or positive-pressure air line with auxiliary self-contained air supply. The following should be effective types of air-purifying respirators: Full-face Organic vapor cartridge with a particulate pre-filter.

Appearance

Physical state Liquid.

Color Clear

Odor Fruity

Odor Threshold < 1 ppb Literature

pH 3.1 - 4.5 ASTM E70

Melting point/range Not applicable to liquids

Freezing point -18 °C ( -0 °F) OECD Test Guideline 102

Boiling point (760 mmHg) 100.7 °C ( 213.3 °F) OECD Test Guideline 103

Flash point closed cup ASTM D 56 (none)

Evaporation Rate (Butyl 1.0 Literature

Acetate (=1)

Flammability (solid, gas) Not applicable to liquids

Lower explosion limit No test data available

Upper explosion limit No test data available

Vapor Pressure 15 mmHg at 20 °C (68 °F) OECD Test Guideline 104

Active ingredient

Relative Vapor Density 1.1 Literature

(air = 1)

9. PHYSICAL AND CHEMICAL PROPERTIES


Relative Density (water = 1) 1.129 at 20°C (68°F) OECD 109

Water solubility 100% at 20°C (68°F) Calculated.

Partition coefficient log Pow: -0.333 Measured

n-octanol/water

Auto-ignition temperature 385°C (725°F) at 1,004 hPa 92/69/EEC A15

Decomposition temperature No test data available

Dynamic Viscosity 2.5 cP at 25°C (77°F) Literature (Brookfield Viscosity

@ 100 rpm, #0 spindle)

Kinematic Viscosity 20.2 mm2/s at 20°C (68°F) Literature

Explosive properties No EEC A14

Oxidizing properties No

Molecular weight No test data available

Percent volatility No test data available

Saturated vapour No test data available

concentration

NOTE: The physical data presented above are typical values and should not be construed as a specification.

Reactivity: No data available

Chemical stability: Thermally stable at typical use temperatures.

Possibility of hazardous reactions: Polymerization will not occur.

Conditions to avoid: Active ingredient decomposes at elevated temperatures.

Incompatible materials: Avoid contact with: Amines. Ammonia. Strong acids. Strong bases. Strong oxidizers. Avoid contact with metals such as: Aluminum. Carbon steel. Copper. Iron. Mild steel.

Hazardous decomposition products: Decomposition products depend upon temperature, air supply and the presence of other materials.

Acute toxicity

Acute oral toxicity Moderate toxicity if swallowed. Swallowing may result in irritation or burns of the mouth, throat, and gastrointestinal tract. Swallowing may result in gastrointestinal irritation or ulceration. Excessive exposure

10. STABILITY AND REACTIVITY

11. TOXICOLOGICAL INFORMATION


may cause: Headache. Dizziness. Anesthetic effects. Drowsiness. Unconsciousness. Other central nervous system effects.

As product: LD50, Rat, male and female, 200 mg/kg

Acute dermal toxicity Prolonged skin contact is unlikely to result in absorption of harmful amounts.

Acute inhalation toxicity Vapor from heated material or mist may cause serious adverse effects, even death. Vapor may cause severe irritation of the upper respiratory tract (nose and throat). Case reports and medical surveys link asthma and respiratory irritation to glutaraldehyde exposure, primarily in medical personnel. Asthma-like symptoms may occur in people prone to respiratory disorders or other allergies. Asthma-like symptoms may include coughing, difficult breathing and a feeling of tightness in the chest. Occasionally, breathing difficulties may be life threatening.

As product: LC50, Rat, female, 4 Hour, dust/mist, 0.28 mg/l LC50, Rat, male, 4 Hour, dust/mist, 0.35 mg/l

Skin corrosion/irritation Brief contact may cause skin burns. Symptoms may include pain, severe local redness and tissue damage.

Serious eye damage/eye irritation May cause severe irritation with corneal injury which may result in permanent impairment of vision, even blindness. Chemical burns may occur. Vapor may cause eye irritation experienced as mild discomfort and redness.

Sensitization Skin contact may cause an allergic skin reaction in a small proportion of individuals. Has caused allergic skin reactions when tested in guinea pigs. Has demonstrated the potential for contact allergy in mice.

May cause allergic respiratory response in a small proportion of individuals.

Specific Target Organ Systemic Toxicity (Single Exposure) May cause respiratory irritation. Route of Exposure: Inhalation Target Organs: Respiratory Tract

Specific Target Organ Systemic Toxicity (Repeated Exposure) Repeated skin contact may result in absorption of amounts which could cause death. May cause nausea and vomiting.


Carcinogenicity

In a NTP chronic 2-year inhalation study on glutaraldehyde, no carcinogenicity was seen in rats or in mice. An increase in large granular lymphocytes in Fischer rats dosed with glutaraldehyde for two years was random or a secondary carcinogenic effect due to a modifying influence on the occurrence of this common neoplasm in this rat strain.

Teratogenicity Has been toxic to the fetus in laboratory animals at doses toxic to the mother. Did not cause birth defects in laboratory animals.

Reproductive toxicity In animal studies, did not interfere with reproduction.

Mutagenicity In vitro genetic toxicity studies were negative in some cases and positive in other cases. Animal genetic toxicity studies were predominantly negative.

Aspiration Hazard Aspiration into the lungs may occur during ingestion or vomiting, causing tissue damage or lung injury.

COMPONENTS INFLUENCING

TOXICOLOGY: Glutaraldehyde Acute dermal toxicity For the 25% aqueous solution: LD50, Rabbit, male and female, > 2,000 mg/kg

Ecotoxicological information on this product or its components appear in this section when such data is available.

Toxicity

Acute toxicity to fish Material is moderately toxic to aquatic organisms on an acute basis (LC50/EC50 between 1 and 10 mg/L in the most sensitive species tested).

LC50, Cyprinodon variegatus (sheepshead minnow), 96 Hour, 64 mg/l

Acute toxicity to aquatic invertebrates LC50, copepod Acartia tonsa, semi-static test, 48 Hour, 5.8 mg/l

Acute toxicity to algae/aquatic plants ErC50, Desmodesmus subspicatus (Scenedesmus subspicatus), 72 Hour, 1.2 mg/l

NOEC, Desmodesmus subspicatus (Scenedesmus subspicatus), 72 Hour, Growth rate inhibition, 0.05 mg/l

Toxicity to bacteria EC50, activated sludge, > 50 mg/l, OECD 209 Test

12. ECOLOGICAL INFORMATION


EC50, Bacteria, 16 Hour, 17 - 25 mg/l

Chronic aquatic toxicity

Chronic toxicity to aquatic invertebrates NOEC, water flea Daphnia magna, flow-through test, 21 d, number of offspring, 0.24 mg/l

Toxicity to Above Ground

Organisms Material is moderately toxic to birds on an acute basis (LD50 between 51 and 500 mg/kg). Material is practically non-toxic to birds on a dietary basis (LC50 > 5000 ppm).

oral LD50, Anas platyrhynchos (Mallard duck), 408

- 466 mg/kg dietary LC50, Colinus virginianus

(Bobwhite quail), > 5,000 ppm dietary LC50, Anas

platyrhynchos (Mallard duck), > 5,000 ppm

Persistence and

degradability

Biodegradability: Material is readily biodegradable. Passes OECD test(s) for ready biodegradability. 10-day Window: Pass

Biodegradation:

73 % Exposure

time: 9 d

Method: OECD Test Guideline 301A or Equivalent 10-day Window: Not applicable Biodegradation: 73 % Exposure time: 28 d

Method: OECD Test Guideline 306 or Equivalent

Theoretical Oxygen Demand: 1.92 mg/mg

Biological oxygen demand (BOD)

Incubation Time

BOD

5 d 28 % 10 d 57 - 63 % 20 d 72 - 74 %

Photodegradation Test Type: Half-life (indirect photolysis)


Sensitizer: OH radicals

Atmospheric half-life:

2.74 Hour Method: Estimated.

Bioaccumulative potential

Bioaccumulation: Bioconcentration potential is low (BCF < 100 or Log Pow < 3). Partition coefficient: n-octanol/water(log Pow): -0.333 Measured

Mobility in soil

Potential for mobility in soil is high (Koc between 50 and 150). Given its very low Henry's constant, volatilization from natural bodies of water or moist soil is not expected to be an important fate process. Partition coefficient(Koc): 120 - 500 Estimated.

Disposal methods: DO NOT DUMP INTO ANY SEWERS, ON THE GROUND, OR INTO ANY BODY OF WATER. All disposal practices must be in compliance with all Federal, State/Provincial and local laws and regulations. Regulations may vary in different locations. Waste characterizations and compliance with applicable laws are the responsibility solely of the waste generator. AS YOUR SUPPLIER, WE HAVE NO CONTROL OVER THE MANAGEMENT PRACTICES OR MANUFACTURING PROCESSES OF PARTIES HANDLING OR USING THIS MATERIAL. THE INFORMATION PRESENTED HERE PERTAINS ONLY TO THE PRODUCT AS SHIPPED IN ITS INTENDED CONDITION AS DESCRIBED IN SDS SECTION: Composition Information. FOR UNUSED & UNCONTAMINATED PRODUCT, the preferred options include sending to a licensed, permitted: Incinerator or other thermal destruction device.

DOT

Proper shipping name Corrosive liquids, toxic, n.o.s.(Glutaraldehyde) UN number UN 2922 Class 8 (6.1) Packing group II

Classification for SEA transport (IMO-IMDG):

Proper shipping name CORROSIVE LIQUID, TOXIC, N.O.S.(Glutaraldehyde)

UN number UN 2922 Class 8 (6.1) Packing group II Marine pollutant Glutaraldehyde Transport in bulk according to Annex I or II of MARPOL 73/78 and the IBC or IGC

Code

13. DISPOSAL CONSIDERATIONS

14. TRANSPORT INFORMATION


Classification for AIR transport (IATA/ICAO):

Proper shipping name Corrosive liquid, toxic, n.o.s.(Glutaraldehyde)

UN number UN 2922

Class 8 (6.1) Packing group II

This information is not intended to convey all specific regulatory or operational requirements/information relating to this product. Transportation classifications may vary by container volume and may be influenced by regional or country variations in regulations. Additional transportation system information can be obtained through an authorized sales or customer service representative. It is the responsibility of the transporting organization to follow all applicable laws, regulations and rules relating to the transportation of the material.

OSHA Hazard Communication Standard This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard,

29 CFR 1910.1200.

Superfund Amendments and Reauthorization Act of 1986 Title III (Emergency

Planning and

Community Right-to-Know Act of 1986) Sections 311 and 312 Acute Health Hazard

Superfund Amendments and Reauthorization Act of 1986 Title III (Emergency

Planning and

Community Right-to-Know Act of 1986) Section 313 This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

Pennsylvania Worker and Community Right-To-Know Act: The following chemicals are listed because of the additional requirements of Pennsylvania law:

Components CASRN

Glutaraldehyde 111-30-8

California Proposition 65 (Safe Drinking Water and Toxic Enforcement Act of

1986) This product contains no listed substances knownto the State of California to cause cancer, birth defects or other reproductive harm, at levels which would require a warning under the statute.

15. REGULATORY INFORMATION


Product Literature Additional information on this product may be obtained by calling your sales or customer service contact.

Revision Identification Number: 101234117 / A212 / Issue Date: 03/16/2015 / Version: 10.2 Most recent revision(s) are noted by the bold, double bars in left-hand margin throughout this document.

Legend ACGIH USA. ACGIH Threshold Limit Values (TLV)

C Ceiling limit DSEN, RSEN Skin and respiratory sensitizer

Information Source and References

This SDS is prepared by Product Regulatory Services and Hazard Communications Groups from information supplied by internal references within our company.

TOUSIMIS RESEARCH CORP. urges each customer or recipient of this SDS to study it carefully and consult appropriate expertise, as necessary or appropriate, to become aware of and understand the data contained in this SDS and any hazards associated with the product. The information herein is provided in good faith and believed to be accurate as of the effective date shown above. However, no warranty, express or implied, is given. Regulatory requirements are subject to change and may differ between various locations. It is the buyer's/user's responsibility to ensure that his activities comply with all federal, state, provincial or local laws. The information presented here pertains only to the product as shipped. Since conditions for use of the product are not under the control of the manufacturer, it is the buyer's/user's duty to determine the conditions necessary for the safe use of this product. Due to the proliferation of sources for information such as manufacturer- specific SDSs, we are not and cannot be responsible for SDSs obtained from any source other than ourselves. If you have obtained an SDS from another source or if you are not sure that the SDS you have is current, please contact us for the most current version.

16. OTHER INFORMATION

1 © 2018


SODIUM PHOSPHATE, DIBASIC for solid (crystalline) Na2HPO4

Product name: SODIUM PHOSPHATE



301-881-2450

[email protected]



Hazard classification Classification according to Regulation (EC) No 1272/2008 The substance is not classified as hazardous to health or the environment according to CLP regulation. Classification according to Directive 67/548/EEC or Directive 1999/45/EC Not applicable Information concerning particular hazards for human and environment: No information known. Other hazards that do not result in classification No information known.

Label elements

Labelling according to Regulation (EC) No 1272/2008 Not applicable Hazard pictograms Not applicable Signal word Not applicable Hazard statements Not applicable Other hazards Results of PBT and vPvB assessment PBT: Not applicable vPvB: Not applicable

1. IDENTIFICATION



2 CATALOG #1051 SODIUM PHOSPHATE, DIBASIC © 2018

Substances

CAS# Designation: 13472-35-0 Sodium dihydrogen phosphate dehydrate

Identification number(s):

EC number: 231-449-2


After inhalation Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor if symptoms persist. Seek immediate medical advice.

After skin contact Instantly wash with water and soap and rinse thoroughly. Seek immediate medical advice.

After eye contact Rinse opened eye for several minutes under running water. Then consult doctor.

After swallowing Seek medical treatment.

Most important symptoms and effects, both acute and delayed No further information available.

Indication of any immediate medical attention and special treatment needed No further information available

Extinguishing media

Suitable extinguishing agents Product is not flammable. Use fire-fighting measures that suit the surrounding fire.

Special hazards arising from the substance or mixture If this product is involved in a fire, the following can be released: Sodium oxide Phosphorus oxides


Protective equipment: Wear self-contained breathing apparatus. Wear full protective suit.





Personal precautions, protective equipment and emergency procedures

Wear protective equipment. Keep unprotected persons away.

Ensure adequate ventilation

Environmental precaution Do not allow product to reach sewage system or water bodies. Do not allow to enter ground/soil.

Methods and material for containment and cleaning up: Collect mechanically.

Prevention of secondary hazards: No special measures required.

Reference to other sections See Section 7 for information on safe handling See Section 8 for information on personal protection equipment. See Section 13 for information on disposal.

Precautions for safe handling

Handle under dry protective gas.

Keep in containers tightly sealed.

Store in cool, dry place in tightly closed containers.

Information about protection against explosions and fires: The product is not flammable

Conditions for safe storage, including any incompatibilities

Storage

Requirements to be met by storerooms and containers: No special requirements.

Information about storage in one common storage facility: Store away from water. Store away from oxidizing agents.

Further information about storage conditions: Store under dry inert gas. This product is hygroscopic. Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Protect from humidity and keep away from water.

Additional information about design of technical systems:





Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute

Control parameters

Components with critical values that require monitoring at the workplace:

The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace.

Additional information: No data

Exposure controls

Personal protective equipment

General protective and hygienic measures The usual precautionary measures should be adhered to in handling the chemicals. Keep away from foodstuffs, beverages and food. Instantly remove any soiled and impregnated garments. Wash hands during breaks and at the end of work. Maintain an ergonomically appropriate working environment.

Breathing equipment: Use breathing protection with high concentrations.

Recommended filter device for short term use: Use a respirator with type N95 (USA) or PE (EN 143) cartridges as a backup to engineering controls. Risk assessment should be performed to determine if air purifying respirators are appropriate. Only use equipment tested and approved under appropriate government standards.

Protection of hands: Check protective gloves prior to each use for their proper condition. The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer.

Material of gloves Nitrile rubber, NBR

Penetration time of glove material (in minutes) 480

Glove thickness 0.11 mm

Eye protection: Safety glasses

Body protection: Protective work clothing.

Information on basic physical and chemical properties

General Information

Appearance

Form Crystalline

Color White

Smell Not determined



Odor Threshold Not determined

pH Not applicable

Melting point/range Not determined

Boiling point/range Not determined

Sublimation temperature / start Not determined

Infammability solid/gaseous Not determined

Ignition temperature Not determined

Decomposition temperature Not determined

Self-Inflammability Not determined

Danger of explosion Not determined

Critical values for explosion:

Lower Not determined

Upper Not determined

Steam Pressure Not determined

Density at 20°C 1.91 g/cm3

Relative Vapor Density (air = 1) Not applicable

Relative Density (water = 1) Not applicable

Evaporation rate Not applicable

Solubility in / Soluble

Miscibility with Water

Partition coefficient

(n-octanol/water) Not determined

Dynamic Not applicable

Kinematic Not applicable

Other information

No further relevant information available.

Reactivity: No information known.

Chemical stability: Stable under recommended storage conditions.

Thermal decomposition / conditions to be avoided: No decomposition if used and stored according to specifications.

Possibility of hazardous reactions: Reacts with strong oxidizing agents.

Conditions to avoid: No further relevant information available.

Incompatible materials: Water/moisture Oxidising agents

Hazardous decomposition products: Sodium oxide Phosphorus oxides (e.g. P2O5)



Toxicological information on this product or its components appear in this section when such data is available.

Information on toxicological effects

Acute toxicity: The Registry of Toxic Effects of Chemical Substances (RTECS) contains acute toxicity data for this substance.

LD/LC50 values that are relevant for classification: No data

Skin corrosion/irritation May cause irritation

Serious eye damage/eye irritation May cause irritation

Sensitization No sensitizing effect known.

Germ cell mutagenicity: No effects known.

Carcinogenicity: No classification data on carcinogenic properties of this material is available from the EPA, IARC, NTP, OSHA or ACGIH.

Reproductive toxicity: No effects known.

Specific target organ system toxicity – repeated exposure: No effects known

Specific target organ system toxicity – single exposure: No effects known.

Aspiration hazard: No effects known.

Subacute to chronic toxicity: No effects known.

Additional toxicological information: To the best of our knowledge the acute and chronic toxicity of this substance is not fully known.

Ecotoxicological information on this product or its components appear in this section when such data is available.

Toxicity

Aquatic toxicity: No further relevant information available. Persistence and degradability: No further relevant information available.

Bioaccumulative potential




No further relevant information available.

Mobility in soil No further relevant information available. Additional ecological information: General notes: Water hazard class 1 (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities to reach ground water, water course or sewage system. Avoid transfer into the environment.

Results of PBT and vPvB assessment PBT: Not applicable. vPvB: Not applicable. Other adverse effects: No further relevant information available.

Waste treatment methods

Recommendation

Hand over to disposers of hazardous waste.

Must be specially treated under adherence to official regulations.

Consult state, local or national regulations for proper disposal.

Uncleaned packagings:

Recommendation: Disposal must be made according to official regulations.

Recommended cleaning agent: Water, if necessary with cleaning agent.

UN-Number

ADR, AND, IMDG, IATA Not applicable

UN proper shipping name

ADR, AND, IMDG, IATA Not applicable

Transport hazard class(es)

ADR, AND, IMDG, IATA Class Not applicable

Packing group

ADR, IMDG, IATA Not applicable

Environmental hazards: Not applicable

Special precautions for user Not applicable

Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code Not applicable




UN “Model Regulation” -

This information is not intended to convey all specific regulatory or operational requirements/information relating to this product. Transportation classifications may vary by container volume and may be influenced by regional or country variations in regulations. Additional transportation system information can be obtained through an authorized sales or customer service representative. It is the responsibility of the transporting organization to follow all applicable laws, regulations and rules relating to the transportation of the material.

Safety health and environmental regulations/legislation specific for the

substance or mixture

Australian inventory of Chemical Substances Substance is listed.

Standard for the Uniform Scheduling of Drugs and Poisons Substance is not listed.

National regulations

Information about limitation of use: For use only by technically qualified individuals.

Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.

Other regulations, limitations and prohibitive regulations

ELINCS (European List of Notified Chemical Substances) Substance is not listed.

Substance of Very High Concern (SVHC) according to the REACH Regulations

(EC) No. 1907/2006. Substance is not listed.

The conditions of restrictions according to Article 67 and Annex XVII of the

Regulation (EC) No 1907/2006 (REACH) for the manufacturing, placing on the

market and use must be observed.

Substance is not listed.

Annex XIV of the REACH Regulations (requiring Authorisation for use) Substance is not listed.

REACH – Pre-registered substances Substance is listed.

Chemical safety assessment: A Chemical Safety Assessment has not been carried out.

Employers should use this information only as a supplement to other information gathered by them, and should make independent judgment of suitability of this information to ensure proper use and protect the health and safety of employees. This information is furnished without warranty, and any use of the product not in conformance with this Material Safety Data Sheet, or in combination with any other product or process, is the responsibility of the user. Department issuing SDS: Global Marketing Department




Abbreviations and acronyms: ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) GHS: Globally Harmonized System of Classification and Labeling of Chemicals EINECS: European Inventory of Existing Commercial Chemical Substances CAS: Chemical Abstracts Service (division of the American Chemical Society) LC50: Lethal concentration, 50 percent LD50: Lethal dose, 50 percent vPvB: very Persistent and very Bioaccumulative ACGIH: American Conference of Governmental Industrial Hygienists (USA) OSHA: Occupational Safety and Health Administration (USA) NTP: National Toxicology Program (USA) IARC: International Agency for Research on Cancer EPA: Environmental Protection Agency (USA)

1 © 2018


SODIUM PHOSPHATE, MONOBASIC

Product name: SODIUM PHOSPHATE, MONOBASIC



301-881-2450

[email protected]



Classification of the substance or mixture

Not a hazardous substance or mixture.

GHS Label elements, including precautionary statements

Not a hazardous substance or mixture.

Hazardous not otherwise classified (HNOC) or not covered by GHS - none

Substances

Synonyms Sodium dihydrogen phosphatemonohydrate Monosodium phosphate

Formula H2NaO4P * H2O

1. IDENTIFICATION




2 CATALOG #1051 SODIUM PHOSPHATE, MONOBASIC © 2018

Molecular Weight 137.99 g/mol

CAS-No. 10049-21-5

EC-No. 231-449-2 No components need to be disclosed according to the applicable regulations.


If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration.

In case of skin contact Wash off with soap and plenty of water.

In case of eye contact Flush eyes with water as a precaution.

If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water.

Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labeling (see section 2) and/or in section 11

Indication of any immediate medical attention and special treatment

needed No data available

Extinguishing media

Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture Oxides of phosphorus, Sodium oxides





Wear self-contained breathing apparatus for fire-fighting if necessary.

Further information No data available

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing vapours, mist or gas.

For personal protection see Section 8.

Environmental precautions No special environmental precautions required.

Methods and material for containment and cleaning up: Sweep up and shovel. Keep in suitable, closed containers for disposal.

Reference to other sections For disposal see section 13.

Precautions for safe handling

Further processing of solid materials may result in the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration before additional processing occurs.

Provide appropriate exhaust ventilation at places where dust is formed.

For precautions see section 2.

Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place. Hygroscopic Storage class (TRGS 510): Non Combustible Solids

Specific end use(s) Contains no substances with occupational exposure limit values.

Control parameters

Components with workplace control parameters

Contains no substances with occupational exposure limit values.

Exposure controls





Appropriate engineering controls

General industrial hygiene practice.

Personal protective equipment

Eye/face protection Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove’s outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Full contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested: Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested: Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory on ly and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Body protection Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

mailto:[email protected]


Control of environmental exposure No special environmental precautions required.

Information on basic physical and chemical properties

General Information

Appearance

Form Crystalline

Color White

Smell No data available

Odor Threshold No data available

pH 4.1-4.5 at 50 g/l at 25°C (77° F)

Melting point/range No data available

Boiling point/range No data available

Flash point No data available

Evaporation rate No data available

Flammability (solid, gas) No data available

Upper/lower flammability

or explosive limits No data available

Vapour pressure No data available

Vapour density No data available

Relative density No data available

Water solubility No data available

Partition coefficient: n-

octanol/water No data available

Auto-ignition temperature No data available

Decomposition temperature No data available

Viscosity No data available

Explosive properties No data available

Oxidizing properties No data available

Other safety information No data available

Reactivity: No data available




Chemical stability: Stable under recommended storage conditions.

Possibility of hazardous reactions: No data available

Conditions to avoid hygroscopic

Incompatible materials: Strong oxidizing agents, Strong acids

Hazardous decomposition products: Other decomposition products – No data available In the event of fire: see section 5

Information on toxicological effects

Acute toxicity:

No data available

Inhalation: No data available

Dermal: No data available

Skin corrosion/irritation

No data available

Serious eye damage/eye irritation No data available

Repiratory or skin sensitization No data available

Germ cell mutagenicity: No data available

Carcinogenicity

IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH. NTP: No component of this product present at levels great than or equal to 0.1% is identified as known or anticipated carcinogen by NTP.



OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA.

Reproductive toxicity: No data available

Specific target organ system toxicity – repeated exposure: No data available

Specific target organ system toxicity – single exposure: No data available

Aspiration hazard: No data available

Additional toxicological information RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

Toxicity No data available Persistence and degradability No data available

Bioaccumulative potential No data available

Mobility in soil No data available Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted Other adverse effects: No data available

Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company.

Contaminated packaging

Dispose of as unused product.





DOT (US) Not dangerous goods

IMDG Not dangerous goods

IATA Not dangerous goods

SARA 302 Components

No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components

This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards

No SARA Hazards

Massachusetts Right To Know Components

No components are subject to the Massachusetts Right to Know Act.

Pennsylvania Right To Know Components

Sodium dihydrogenorthophosphate monohydrate

CAS-No. 10049-21-5

New Jersey Right To Know Components

Sodium dihydrogenorthophosphate monohydrate

CAS-No. 10049-21-5

California Prop. 65 Components

This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

HMIS Rating Health hazard: 0 Chronic Health Hazard




Flammability: 0 Physical Hazard 0 NFPA Rating Health hazard: 0 Fire Hazard: 0 Reactivity Hazard: 0 Further information Copyright 2016 tousimis® License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. tousimis® and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.tousimis.com for additional terms and conditions of sale. Preparation Information tousimis® Product Safety 301-881-2450

http://www.tousimis.com/

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