May 28, 2021

FORWARD LOOKING STATEMENTS: Statements in this document relating to Limestone Bancorp’s plans, objectives, expectations or futureperformance are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. The words “believe,”“may,” “should,” “anticipate,” “estimate,” “expect,” “intend,” “objective,” “possible,” “seek,” “plan,” “strive” or similar words, or negatives ofthese words, identify forward-looking statements that involve risks and uncertainties. These forward looking statements include statementsrelated to the expected timing and benefits of the proposed branch acquisition and estimates of deposits, loans and other assets to beacquired. Although the Company's management believes the assumptions underlying the forward-looking statements contained herein arereasonable, any of these assumptions could be inaccurate. Therefore, there can be no assurance the forward-looking statements includedherein will prove to be accurate. Factors that could cause actual results to differ from those discussed in forward-looking statements include,but are not limited to: economic conditions both generally and more specifically in the markets in which the Company and its subsidiariesoperate; competition for the Company's customers from other providers of financial services; government legislation and regulation, whichchange from time to time and over which the Company has no control; changes in interest rates; material unforeseen changes in liquidity,results of operations, or financial condition of the Company's customers; and other risks detailed in the Company's filings with the Securitiesand Exchange Commission, all of which are difficult to predict and many of which are beyond the control of the Company. See Risk Factorsoutlined in the Company's Form 10-K for the year ended December 31, 2020 and Form 10-Q filings for the periods thereafter.

NON-GAAP FINANCIAL MEASURES: These slides contain non-GAAP financial measures which the Company’s management uses in their analysisof the Company’s performance OR management believes facilitates an understanding of the Company’s performance. For purposes ofRegulation G, a non-GAAP financial measure is a numerical measure of the registrant’s historical or future financial performance, financialposition or cash flows that excludes amounts, or is subject to adjustments that have the effect of excluding amounts, that are included in themost directly comparable measure calculated and presented in accordance with GAAP in the statement of income, balance sheet or statementof cash flows (or equivalent statements) of the issuer; or includes amounts, or is subject to adjustments that have the effect of includingamounts, that are excluded from the most directly comparable measure so calculated and presented. In this regard, GAAP refers to generallyaccepted accounting principles in the United States. Pursuant to the requirements of Regulation G, Limestone Bancorp, Inc. has providedreconciliations, as necessary, of the non-GAAP financial measure to the most directly comparable GAAP financial measure.

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Limestone Bancorp is a Kentucky-based bank holding company – Nasdaq: LMST

Limestone Bank is the 11th largest bank domiciled in Kentucky based on total assets

Corporate headquarters in Louisville, Ky.

Approximately $1.362 billion in assets and 225 associates (fte) at 3.31.21

Broad scope of high-quality retail and business banking products & services

Management team assembled under leadership of John T. Taylor, President & CEO with extensive market knowledge and community relationships

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About Limestone Bancorp and Limestone Bank

Management TeamJohn T. TaylorPresident & CEO, Limestone BancorpChairman, President & CEO, Limestone BankJoined July 2012Over 30 years in industryAmerican Founders Bank – Lexington, KYPNC Bank, NA – President of Ohio & N. KY Region

Phillip W. BarnhouseCFO, Limestone Bancorp since January 2012CFO, Limestone BankJoined Ascencia Bank (former Limestone Subsidiary)Sept 1998

Previous Experience:Arthur Andersen LLP – Chattanooga, TN

Stephanie RennerSenior Vice President, General Counsel, Limestone BankJoined August 2012

Previous experience:American Founders BankStites & Harbison, PLLC – Lexington, KYBryan Cave, LLP – Los Angeles, CA

John R. DavisExecutive Vice President, Chief Credit Officer, Limestone BankJoined August 2012

25 Years Previous Experience:American Founders Bank – Lexington, KYNational City Bank – Louisville, KY andDayton & Cleveland, OH

Joseph C. SeilerExecutive Vice President, Head of Commercial Banking, Limestone BankJoined April 2013

25 Years Previous Experience:PNC Bank, NA – Louisville, KYNational City Bank – Louisville, KY

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Board of DirectorsW. Glenn HoganFounder, CEO and PresidentHogan Real EstateLouisville, KY

Director since 2006

Michael T. LevyPresident MuirfieldInsurance LLCLexington, KY

Director since 2014

James M. ParsonsChief Financial Officer Ball Homes LLCLexington, KY

Director since 2015

Bradford T. RayRetired CEO and ChairmanSteel Technologies, Inc.Louisville, KY

Director since 2014

Kevin J. KoomanPartnerPatriot Financial Partners LPPhiladelphia, PA

Director since 2019

Dr. Edmond J. SeifriedPrincipal S&B West LLCBethlehem, PA

Director since 2015

John T. TaylorPresident & CEO, Limestone BancorpChairman, President & CEO, Limestone Bank

Director since 2012

Celia CatlettFormer General Counsel and Corporate Secretary, Texas Roadhouse, Inc.Louisville, KY

Director Since 2018

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Highlights and Accomplishments Talent acquisition – Board, management, and production team

Enterprise Risk Management system implementation & strategic acquisition Credit adjudication and centralized operations Regulatory relations Compliance management systems Core system conversion 2018

Quality loan production; deposit mix shift; solid asset quality; improving profitability metrics

Financial transactions: Q2-20: Issued $8.0 million subordinated debt; qualifying Tier 2 Capital; retired $5.0 million senior Q3-19: Issued $17.0 million subordinated debt; qualifying Tier 2 Capital; prepaid $5.0 million senior Q2-18: Retired all issued and outstanding preferred stock in $3.5 million transaction Q1-18: Issued 1.15 million shares of common stock raising $15 million in new capital for Bancorp Q4-17: Reversed deferred tax asset valuation allowance restoring $31.3 million net dta Q2-17: Completed $10 million senior borrowing and contributed $9 million in new capital to Bank Q2-16: Issued 800,000 shares of common stock raising $5 million in new capital for Bancorp

Strategic Plan: Organic growth in rural and metro markets and strategic acquisitions Q4-19: Completed acquisition of 4 branches; $132 mil deposits & $127 mil loans

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Limestone Bank Locations

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14 counties across the Commonwealth of Kentucky

21 Banking Centers

1 new banking center opened in Louisville, KY (Jefferson) in Q1-21

Closing two older banking centers in Owensboro and relocating to new banking center in same community

Metro Market OverviewLouisville Lexington Owensboro Bowling Green

Corporate Headquarters: Brown-Forman, Churchill Downs, Humana, Kindred Healthcare, Papa John’s International, Texas Roadhouse, and Yum! Brands

Corporate Headquarters: Fasig Tipton, Jif (peanut butter), Keeneland, Lexmark, and TempurSealy

Corporate Headquarters: Owensboro Health

Corporate Headquarters: Camping World, Fruit of the Loom, HouchensIndustries, and the Medical Center at Bowling Green

Other large employers:UPS, Ford Motor Company, GE Appliances, and NortonHealthcare

Other large employers:Xerox, Toyota, IBM, Lockheed Martin, and Valvoline

Other large employers:Kimberly-Clark, US Bank Mortgage Processing, and Toyotetsu

Other large employers:General Motors Corvetteplant, Rafferty’s Restaurants

Universities: University of Louisville and Bellarmine University

Universities: University of Kentucky and TransylvaniaUniversity

Universities: Kentucky Wesleyan University and Brescia University

Universities: Western Kentucky University

Deposits in Market:$21.2 billionLimestone market share 1.0%MSA Population – 1.265 mil(69th Largest in US)

Note: Four largest cities in KYSource: United States Census Bureau

Deposits in Market:$7.9 billionLimestone market share 1.0%MSA Population – 517k (138th largest in US)

Deposits in Market:$2.7 billionLimestone market share 3.6%MSA Population – 119k(363rd largest in US)

Deposits in Market:$2.7 billionLimestone market share 1.2%MSA Population - 179k (270th largest in US)

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Financial Summary

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Limestone Bancorp, Inc.Balance Sheet and Share Data As of Unaudited($ in 000's) 12/31/2016 12/31/2017 12/31/2018 12/31/2019 12/31/2020 3/31/2021Cash and equivalents 66,316$ 34,103$ 35,361$ 30,203$ 67,693$ 83,847$ Securities 194,608 152,720 201,192 209,000 203,862 218,944 Loans, net of allowance 630,269 703,983 756,364 917,895 949,638 966,110 Premises and equipment, net 17,848 16,789 15,705 20,558 19,593 20,405 Other real estate owned 6,821 4,409 3,485 3,225 1,765 1,765 FHLB bank stock 7,323 7,323 7,233 6,237 5,887 5,810 Bank owned life insurance 14,838 15,229 15,646 16,037 23,441 23,601 Deferred tax assets, net - 31,313 29,282 27,765 25,714 24,992 Goodwill & intangibles - - - 8,752 8,496 8,433 Other assets 7,154 4,932 5,424 6,107 6,213 7,804 Total assets 945,177$ 970,801$ 1,069,692$ 1,245,779$ 1,312,302$ 1,361,711$

Certificates of deposit 444,639$ 424,235$ 450,886$ 476,534$ 367,552$ 355,309$ Interest checking 103,876 99,383 94,269 146,038 190,625 211,322 Money market 142,497 151,388 171,924 160,837 175,785 180,137 Savings 34,518 34,632 34,534 56,015 142,623 151,340 Demand deposits 124,395 137,386 142,618 187,551 243,022 268,882 Fed funds purchased and repos - - - - - - FHLB advances 22,458 11,797 46,549 61,389 20,623 20,613 Junior subordinated debt & subordinated notes 24,150 23,250 21,000 38,000 46,000 46,000 Senior debt - 10,000 10,000 5,000 - - Other l iabil ities 15,911 6,057 5,815 8,665 10,048 8,588 Total l iabil ities 912,444 898,128 977,595 1,140,029 1,196,278 1,242,191

Common stockholders' equity 29,962 69,902 92,097 105,750 116,024 119,520 Preferred stockholders' equity 2,771 2,771 - - - - Total stockholders' equity 32,733 72,673 92,097 105,750 116,024 119,520

Total l iabil ities and stockholders' equity 945,177$ 970,801$ 1,069,692$ 1,245,779$ 1,312,302$ 1,361,711$

Ending common and nonvoting common shares out 6,224,533 6,259,864 7,462,720 7,471,975 7,498,865 7,594,499 Book value per common share 4.81$ 11.17$ 12.34$ 14.15$ 15.47$ 15.74$ Tangible book value per common share 4.79$ 11.17$ 12.34$ 12.98$ 14.34$ 14.63$

Financial Summary

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• Income tax expense for 2019 and 2020 was positively impacted by approximately $1.6 mil and $478k, respectively, by current & deferred tax benefits from KY tax law changes – EPS impact was 21 cents per share in 2019 & 6 cents per share in 2020.

• Beginning in 2021, Kentucky bank franchise tax (capital tax) eliminated and replaced with conventional state income tax at 5% statutory rate.

Limestone Bancorp, Inc. 3-MonthsIncome Statement and Share Data Unaudited($ in 000's) 2016 2017 2018 2019 2020 2021Interest income 35,602$ 37,522$ 43,461$ 49,584$ 50,753$ 12,250$ Interest expense 5,981 6,405 9,790 14,234 10,152 1,570 Net interest income 29,621 31,117 33,671 35,350 40,601 10,680 Provision (negative provision) for loan losses (2,450) (800) (500) - 4,400 350 Net int income after provision for loan losses 32,071 31,917 34,171 35,350 36,201 10,330 Noninterest income: Service charges on deposit accounts 1,958 2,253 2,355 2,381 2,268 548 Interchange fees 849 972 1,831 2,438 3,376 960 Oreo income 456 - - - - - Gain (loss) on sale/calls of securities 216 288 (6) (5) (5) - Income from bank owned life insurance 417 412 437 410 424 165 Other 868 930 1,162 694 781 211 Total noninterest income 4,764 4,855 5,779 5,918 6,844 1,884 Noninterest expense: Salaries and benefits 15,508 15,090 15,489 16,233 17,751 4,482 Occupancy and equipment 3,517 3,420 3,586 3,522 4,001 1,060 Data processing expense 1,185 1,256 1,192 1,259 1,502 378 Deposit account related expense 896 823 1,224 1,890 491 Marketing expense 973 1,098 1,114 908 629 182 Deposit & state franchise tax 965 956 1,118 1,210 1,475 90 FDIC insurance 1,660 1,412 557 211 229 135 Professional fees 1,568 978 814 769 937 236 Litigation and loan collection expense 8,805 179 245 189 200 66 Oreo expense 1,541 1,973 868 368 63 11 Other 3,845 2,960 3,320 4,377 3,739 853 Total noninterest expense 39,567 30,218 29,126 30,270 32,416 7,984 Income (loss) before taxes (2,732) 6,554 10,824 10,998 10,629 4,230 Income tax expense (benefit) 21 (31,899) 2,030 480 1,624 1,008 Net income (loss) after tax (2,753) 38,453 8,794 10,518 9,005 3,222 Basic and diluted income (loss) per share (0.46)$ 6.15$ 1.23$ 1.41$ 1.20$ 0.43$

For the year ended Dec 31,

Investment Portfolio

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At March 31, 2021, $27.7 million, $9.5 million, and $2.5 million of the bank’s CLOs were AA, A, and BBB rated, respectively. CLOs are floating rate, with rates set on a quarterly basis at three-month LIBOR plus a spread.

March 31, 2021 Amortized Gross Unrealized Gross Unrealized Fair(in thousands) Cost Gains Losses ValueAgency Securities 29,345$ 493$ (19)$ 29,819$ MBS - CMO (agency issued) 75,303 2,295 (302) 77,296 Municipals (HTM) 41,254 37 (673) 40,618 CLOs 40,185 - (566) 39,619 Corporates 31,655 394 (1,093) 30,956 Totals 217,742$ 3,219$ (2,653)$ 218,308$

Loan Portfolio

Commercial & industrial loans include:

• $20.3 million of SBA PPP loans at 12.31.2020

• $27.9 million of PPP loans at 3.31.2021

• PPP fees are recognized in income on the level yield method over the life of the related loan

• Round 1 &2 PPP loans totaled $42.4 million and the resulting PPP fees totaled $1.7 million

• Round 3 PPP loans through the date of publication totaled $23.5 million and the resulting PPP fees totaled $2.3 million

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($ in 000's) 12/31/2019 12/31/2020 3/31/2021Commercial & Industrial 145,551$ 208,244$ 216,976$ Construction & Development 64,911 92,916 87,249 1-4 Family Residential 226,629 188,955 176,996 CRE - Own Occupied 85,700 87,042 93,319 CRE - Non Owner Occupied 169,759 179,352 209,686 CRE - Farm 79,118 70,272 68,218 Multifamily 70,950 61,180 63,706 Agricultural 35,064 42,044 33,727 Consumer & Other 48,589 32,076 28,988

926,271$ 962,081$ 978,865$

Loan Portfolio and Asset Quality Trends

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Loans by Grade($ in 000's) 12/31/2016 12/31/2017 12/31/2018 12/31/2019 12/31/2020 3/31/2021Pass 586,430 673,033 745,604 888,707 926,025 942,492 Watch 30,431 25,715 13,164 27,522 18,879 17,929 Special Mention 497 164 113 - - - Substandard 21,878 13,203 6,363 10,042 17,177 18,444 Doubtful - - - - - - Total 639,236 712,115 765,244 926,271 962,081 978,865

Non-Performing Assets($ in 000's) 12/31/2016 12/31/2017 12/31/2018 12/31/2019 12/31/2020 3/31/2021Nonaccrual loans 9,216 5,457 1,991 1,528 1,676 1,996 Troubled debt restructurings on accrual 5,350 1,217 910 475 480 399 Loans past due 90 days + - 1 - - - - Other real estate owned 6,821 4,409 3,485 3,225 1,765 1,765 Other repossessed assets - - - - - - Total 21,387 11,084 6,386 5,228 3,921 4,160

NPAs to total assets % 2.26% 1.14% 0.60% 0.42% 0.30% 0.31%

Tier 1 Capital 57,642 81,393 100,429 112,959 130,006 134,110 Allowance for loan losses 8,967 8,202 8,880 8,376 12,443 12,755 Tier 1 Capital + ALLL 66,609 89,595 109,309 121,335 142,449 146,865

Classfied Assets Coverage Ratio 43.09% 19.66% 9.01% 10.93% 13.30% 13.76%

Deposits

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($ in 000's) 12/31/2017 % to Total 12/31/2018 % to Total 12/31/2019 % to Total 12/31/2020 % to Total 3/31/2021 % to TotalNon-interest demand 137,386$ 16.2% 142,618$ 15.9% 187,551$ 18.3% 243,022$ 21.7% 268,882$ 23.0%Interest checking 99,383 11.7% 94,269 10.5% 146,038 14.2% 190,625 17.0% 211,322 18.1%Savings 34,632 4.1% 34,534 3.9% 56,015 5.5% 142,623 12.7% 151,340 13.0%Money Market 151,388 17.9% 171,924 19.2% 160,837 15.7% 175,785 15.7% 180,137 15.4%Certificates of Deposit 424,235 50.1% 450,886 50.4% 476,534 46.4% 367,552 32.8% 355,309 30.4%Total Deposits 847,024$ 100.0% 894,231$ 100.0% 1,026,975$ 100.0% 1,119,607$ 100.0% 1,166,990$ 100.0%

Capital Ratios

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BASEL III Minimum Capital Requirements 12/31/2016 12/31/2017 12/31/2018 12/31/2019 12/31/2020 3/31/2021Tier 1 leverage ratio 4.000% 4.000% 4.000% 4.000% 4.000% 4.000%Common equity tier 1 rbc ratio 4.500% 4.500% 4.500% 4.500% 4.500% 4.500%Tier 1 risk based capital ratio 6.000% 6.000% 6.000% 6.000% 6.000% 6.000%Total risk-based capital ratio 8.000% 8.000% 8.000% 8.000% 8.000% 8.000%

BufferCapital Conservation Buffer 0.625% 1.250% 1.875% 2.500% 2.500% 2.500%

Minimum Capital Requirements plus BufferCommon equity tier 1 rbc ratio 5.125% 5.750% 6.375% 7.000% 7.000% 7.000%Tier 1 risk based capital ratio 6.625% 7.250% 7.875% 8.500% 8.500% 8.500%Total risk-based capital ratio 8.625% 9.250% 9.875% 10.500% 10.500% 10.500%

Bancorp 12/31/2016 12/31/2017 12/31/2018 12/31/2019 12/31/2020 3/31/2021 Well AdequateTier 1 leverage ratio 5.27% 7.11% 9.00% 8.30% 8.24% 8.59% n/a 4.0%Common equity tier 1 rbc ratio 5.20% 6.92% 9.44% 8.32% 8.72% 8.96% n/a 4.5%Tier 1 risk based capital ratio 6.99% 8.44% 11.08% 9.32% 9.67% 10.00% n/a 6.0%Total risk-based capital ratio 10.21% 10.55% 12.23% 11.85% 13.14% 13.42% n/a 8.0%

Common equity tier 1 capital ($ in 000's) 36,199$ 54,535$ 80,219$ 83,683$ 94,166$ 98,656$ Total tier 1 capital 48,713 66,487 94,153 93,731 104,472 110,117 Total regulatory capital 71,109$ 83,072$ 103,978$ 119,186$ 141,915$ 147,872$

BankTier 1 leverage ratio 6.24% 8.70% 9.60% 9.99% 10.21% 10.44% 5.0% 4.0%Common equity tier 1 rbc ratio 8.28% 10.35% 11.83% 11.25% 12.05% 12.21% 6.5% 4.5%Tier 1 risk based capital ratio 8.28% 10.35% 11.83% 11.25% 12.05% 12.21% 8.0% 6.0%Total risk-based capital ratio 9.88% 11.61% 12.88% 12.08% 13.20% 13.37% 10.0% 8.0%

Common equity tier 1 capital ($ in 000's) 57,642$ 81,393$ 100,429$ 112,959$ 130,006$ 134,110$ Total tier 1 capital 57,642 81,393 100,429 112,959 130,006 134,110 Total regulatory capital 68,773 91,305 109,309 121,335 142,449 146,865

Prompt Corrective Action (PCA) Ratio must be > than or equal to.

PCA Levels*

Deferred Tax Asset (DTA)

Deferred Tax Asset – The Company has a net deferred tax asset of $25.0 million at March 31, 2021. Ourability to utilize deferred tax assets depends upon generating sufficient future levels of taxable income.Federal NOL’s total $94.0 million and begin to expire in 2032 and State NOL’s total $30.8 million andbegin to expire in 2026.

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Deferred tax assets and liabilities at:($ in 000's)

12/31/2017 12/31/2018 12/31/2019 12/31/2020 3/31/2021Deferred tax assets: Net operating loss carryforward 25,645$ 24,507$ 22,915$ 22,012$ 20,966$ Allowance for loan losses 1,723 1,865 2,090 3,104 3,183 Other real estate owned write-down 2,432 2,611 2,665 914 914 Other 2,388 2,341 2,089 1,676 2,080

32,188$ 31,324$ 29,759$ 27,706$ 27,143$

Deferred tax liabilities: FHLB stock dividends 557$ 557$ 563$ 478$ 471$ Other 318 366 1,431 1,514 1,680

875 923 1,994 1,992 2,151 Net def tax assets before val allow 31,313 30,401 27,765 25,714 24,992 Valuation allowance - (1,117) - - - Net deferred tax assets 31,313 29,284 27,765 25,714 24,992

NOL Useful Life Table:$ in (000's)

Year of Year of Vintage Expiration Federal Vintage Expiration State

2005 2025 -$ 2006 2026 2,477$ 2007 2027 2,232$ 2008 2028 2,562$ 2009 2029 1,539$ 2010 2030 1,089$ 2011 2031 1,736$

2012 2032 12,976$ 2012 2032 1,594$ 2013 2033 31,339$ 2013 2033 2,258$ 2014 2034 19,023$ 2014 2034 1,197$ 2015 2035 17,351$ 2015 2035 -$ 2016 2036 11,498$ 2016 2036 1,850$ 2017 2037 1,858$ 2017 2037 2,438$ 2018 n/a -$ 2018 n/a 3,070$ 2019 n/a -$ 2019 n/a 3,577$ 2020 n/a -$ 2020 n/a 3,157$

94,045$ 30,776$ Statutory Rates: Federal 21% and State 5%

Deferred Tax Asset (DTA)As of 3.31.2021, LMST’s net DTA totaled approximately $25.0 million. Deferred tax assets and liabilities are measured using current enacted tax rates (currently 21% federal & 5% state).

• Section 382 of the Internal Revenue Code governs DTA impairment and “ownership change”.• An “ownership change” is defined as a more than 50% change in ownership – complex assessment.• 382 imposes an annual ceiling on future use of the Company’s NOLs, credit carry-forwards and built-in losses.• Tends to slow rate of NOL utilization (reducing present value of tax savings).• Some NOLs and other tax benefits could expire before utilization is allowed if the Company does not generate

sufficient taxable income.

• In May 2021, LMST extended a tax benefits preservation plan to June 30, 2024.• Under Section 382 of the IRS Code, a permanent impairment of a substantial portion of the DTA could be

triggered if shareholders owning 5% or more of the Company increase their ownership by more than 50 percentage points over a defined period of time.

• The tax benefits preservation plan is designed to reduce the likelihood of an “ownership change”.• Any shareholder or group that acquires ownership of 5% or more of the Company could be subject to significant

dilution in its holdings if our Board does not approve such acquisition.• Existing shareholders of 5% or more are also subject to dilution if they increase their holdings without Board

approval.

• In May 2021, shareholders approved extending an amendment to the articles of incorporation to further protect the long-term value of the Company’s NOLs.

• The amendment provides a means to block transfers of our common shares that could result in an ownership change under Section 382.

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Subordinated Debt

Issued amount: $17.0 million – Issued July 23, 2019; $ 8.0 million - Issued July 31, 2020;Qualifying Tier 2 CapitalRated BBB by Egan Jones Rating Company

Rate: Fixed at 5.75% for Five Years then floating at 3.95% over three-month libor for the final five years

Repay terms: Interest only semi-annually; principal due at maturity.

Maturity: July 31, 2029; pre-payable without penalty beginning July 31, 2025

Collateral: Unsecured

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Limestone Bancorp, Inc. - Junior Subordinated Debt

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OptionalLiquidation Issuance Prepayment Maturity

Description Value Date Date Rate Date

Statutory Trust I 3,000,000 2/13/2004 3/17/2009 3m Libor + 2.85% 2/13/2034

Statutory Trust II 5,000,000 2/13/2004 3/17/2009 3m Libor + 2.85% 2/13/2034

Statutory Trust III 3,000,000 4/15/2004 6/17/2009 3m Libor + 2.79% 4/15/2034

Statutory Trust IV 10,000,000 12/14/2006 3/1/2012 3m Libor + 1.67% 3/1/2037

Total 21,000,000

Non-GAAP Financial Measures

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Limestone Bancorp, Inc.(in thousands, except share and per share data) As of As of As of As of As of As ofTangible book value per share 12/31/2016 12/31/2017 12/31/2018 12/31/2019 12/31/2020 3/31/2021Common shareholder's equity 29,962$ 69,902$ 92,097$ 105,750$ 116,024$ 119,520$ Less: Intangible assets 140 - - 8,752 8,496 8,433 Tangible common equity 29,822 69,902 92,097 96,998 107,528 111,087

Shares outstanding 6,224,533 6,259,864 7,462,720 7,471,975 7,498,865 7,594,499 Tangible book value per common share $ 4.79 $ 11.17 $ 12.34 $ 12.98 $ 14.34 $ 14.63 Book value per common share $ 4.81 $ 11.17 $ 12.34 $ 14.15 $ 15.47 $ 15.74

Tangible capital ratio(in thousands) As of As of As of As of As of As of

12/31/2016 12/31/2017 12/31/2018 12/31/2019 12/31/2020 3/31/2021Tangible common equity 29,822$ 69,902$ 92,097$ 96,998$ 107,528$ 111,087$

Total assets 945,177 970,801 1,069,692 1,245,779 1,312,302 1,361,711

Tangible capital ratio 3.2% 7.2% 8.6% 7.8% 8.2% 8.2%

Tangible book value per common share is a non-GAAP financial measure derived from GAAP-based amounts. Tangible book value per common share is calculated by excluding the balance of intangible assets from common stockholders’ equity. Tangible book value per common share is calculated by dividing tangible common equity by common shares outstanding, as compared to book value per common share, which is calculated by dividing common stockholders’ equity by common shares outstanding. Management believes this is consistent with bank regulatory agency treatment, which excludes intangible assets from the calculation of risk-based capital.