Department of Medicine

MISSION

TO SERVE THE PATIENT AND ADVANCE THE SCIENCE THROUGH EDUCATION AND RESEARCH.

MAYO CLINIC

PATIENT CARE EDUCATION RESEARCH

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The Division of Cardiovascular Diseases at Mayo Clinic is composed of staff doctors in a highly integrated and cooperative group practice. The Division is committed to providing the best possible care to patients with disorders of the heart, arteries, veins and lymphatic vessels. Mem-bers of the Division care for approximately 59,000 patients annually. The practice is supported by many laboratories, subspecialty clinics and preventive health programs, as well as by active basic and clinical research programs and continuing education programs. There is close coordina-tion and collaboration between the Adult and Pediatric Cardiologists to provide integrated care for patients of all ages.

Patient CareThe eld of cardiology and vascular medicine is dy-

namic with new diagnostic techniques, drugs and inter-ventions continuously being introduced. Division members are organized into a variety of subspecialty groups, each focusing on a particular segment of cardiology or vascular medicine. Their specic expertise is a resource for every-one, enabling the entire Division to stay at the leading edge of change in cardiology and vascular medicine.

Mayo’s Cardiac Catheterization Lab is one of the largest facilities in the world focusing on clinical practice, educa-tion and research in invasive cardiology. The Cardiac Cath-eterization Lab provides training in invasive cardiology for the Adult Cardiovascular Diseases training program and has an ACGME–accredited training program in Interven-tional Cardiology. In addition to clinical research, there is an active basic investigational laboratory, a coronary angiographic core laboratory, a data analysis center and a quality assurance unit.

The Mayo Cardiovascular Ultrasound Imaging and Hemodynamic Laboratory (Echo Lab) is the largest clini-cal, educational and research echocardiographic laboratory facility of its kind in the world. Outpatient and inpatient studies are performed routinely with state-of-the-art equipment. Over 30,000 comprehensive patient examina-tions are performed annually using transthoracic and transesophageal echocardiography.

Mayo’s Electrophysiology Laboratory has over 25 years’ experience diagnosing and managing cardiac arrhythmias. Mayo Clinic is a national leader in the areas of catheter ablation and implantable devices, including the use of advanced technology for treating arrhythmias. Over 10,000 electrophysiology procedures have been performed during the past six years.

Mayo Clinic Rochester’s Implantable Device Clinic is a collaborative effort of physicians and specially trained nurses within the Division of Cardiovascular Diseases. This clinic evaluates and manages the care of patients prior to and following the implantation of cardiac pacemakers and automatic internal cardioverter debrillator systems. The Device Clinic implants approximately 1,300 devices per year, and follows approximately 4,000 patients on a regular basis (at least four times per year by phone).

EducationEducation within the Division of Cardiovascular Diseas-

es is multifaceted and encompasses programs earmarked for physicians, paramedical providers, technical staff and

Cardiovascular Diseases

Heart specialists at Mayo Clinic have evaluated and treated

more than 18,000 children and adults with congenital heart

disease over the past 60 years. Mayo surgeons perform more

than 500 operations each year to repair congenital heart

defects. The Center for Congenital Heart Disease in Rochester

is dedicated to the needs of congenital heart patients. Mayo’s

research on new treatments and their effectiveness have

helped move treatment of these disorders from the rare to the

mainstream, with predictably high rates of success.

Integrated Approach to TreatmentAt Mayo, cardiologists, cardiovascular surgeons, anesthesiolo-

gists and other specialists work closely together on a daily ba-

sis to care for patients with congenital heart disease. At Mayo

Clinic Rochester, patients with congenital heart disease can be

cared for from birth to old age by the same group of doctors.

For more information, go to www.mayoclinic.org/congenital-heart

The Center for Congenital Heart Disease

David L. Hayes, M.D, ChairDouglas A. Parks, AdministratorJonathan W. Curtright, Administrator

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patients. Cardiologists from the Division actively participate in teaching medical students at Mayo Clinic College of Medicine in their rst and second years. During this time, medical students have the opportunity to initiate research projects with clinical staff. Also, during the third and fourth years, both hospital-based inpatient clinical rotations as well as clinical CV laboratory-based rotations are available.

The Division is also active in postgradu-ate teaching activities with approximately 70 rst-year residents from the Mayo Graduate School of Medicine rotating through inpa-tient cardiovascular services. Details of these activities include:

n Internal Medicine residents have the op- portunity to take Division electives within the clinical laboratories and outpatient subspecialty clinics.

n Third-year internal medicine residents ro- tate for one month in the Coronary Care Unit and for one month in supervisory roles over rst-year residents. Residents may choose from an array of cardiovascu- lar educational conferences and have am-

ple opportunities to collaborate on research projects with Division consulting staff.

The Cardiovascular Fellowship Program admits eight to nine new fellows each year via the match system, with one to three positions designated in the NIH-training or Clinical Investigator (CI) tracks. At any given time, approximately 40 to 50 fellows are in training, including those who are present for special one-year fellowships. Features of the program include:

n The program encompasses a four-to- ve-year time frame, including a mini- mum of one year of research and a varia- tion of training tracks which may include up to two years of advanced training in one of several subspecialty areas within Cardiovascular Diseases.

n A new Education Simulation Center promises to bring new opportunities for the teaching and evaluation of fellows learning invasive techniques. Multiple outpatient subspecialty clinics also facili- tate disease-oriented research and clinical care.

n More than 20 weekly didactic conferences are offered, both Division-wide and within the laboratories, facilitating fellow education and experience in the presenta- tion of educational and research curricula to colleagues.

Over 30 CME programs are either hosted or co-hosted by the Division of Cardiovas-cular Diseases annually. The Mayo Board Review course for cardiovascular trainees and individuals renewing their ABIM certi-cates, attracts well over 700 attendees yearly, eclipsing the ACC Board Review Course in attendance and popularity.

ResearchResearch within the Division of Car-

diovascular Diseases is exemplied by incredible depth and diversity focusing on discovery and translation to patient care. The Division’s rich tradition in cardiovascular research is recognized by the National Insti-

Cardiovascular Diseases

ChairDavid L. Hayes, M.D.

AdministratorsDouglas A. ParksJonathan W. Curtright

ConsultantsMichael J. Ackerman, M.D., Ph.D.Thomas G. Allison, MPH, Ph.D.Nasser M. Ammash, M.D.Samuel J. Asirvatham, M.D.William T. Bardsley, M.D.Gregory W. Barsness, M.D.Thomas Behrenbeck, M.D.Malcolm R. Bell, M.D.Marek Belohlavek, M.D.Patricia J. Best, M.D.Sandra K. Birchem, D.O.Daniel D. Borgeson, M.D.David Bradley, M.D., Ph.D.Peter A. Brady, M.D.John F. Bresnahan, M.D.Frank Y. Brozovich, M.D., Ph.D.Charles J. Bruce, M.D.John C. Burnett, Jr., M.D.Allison K. Cabalka, M.D.Charles R. Cagin, D.O.Mark J. Callahan, M.D.Frank Cetta, M.D.Yongmei Cha, M.D.Krishnaswamy Chandrasekaran, M.D.Panithaya Chareonthaitawee, M.D.Horng H. Chen, M.D.Stuart C. Christenson, M.D.Janice Clarke, M.D.Alfredo L. Clavell, M.D.Ian P. Clements, M.D.Roger L. Click, M.D.Heidi M. Connolly, M.D.Leslie T. Cooper, Jr., M.D.Mark G. Costopoulos, M.D.Kevin T. Cragun, M.D.Jack T. Cusma, Ph.D.Laura A. Diamondopoulos, M.D.David J. Driscoll, M.D.Brooks S. Edwards, M.D.Ben W. Eidem, M.D.Raul E. Espinosa, M.D.Titus C. Evans, Jr., M.D.David A. Foley, M.D.Robert P. Frantz, M.D.William K. Freeman, M.D.Paul A. Friedman, M.D.Robert L. Frye, M.D.W. Bruce Fye, M.D.Gerald T. Gau, M.D.Bernard J. Gersh, M.D.Raymond J. Gibbons, M.D.Martha Grogan, M.D.George M. Gura, M.D.Donald J. Hagler, M.D.John H. Haley, M.D.Stephen C. Hammill, M.D.continued on next page

Cardiovascular Diseases

Heart disease is the number one killer of

women, resulting in approximately 1/2 mil-

lion deaths annually. Mayo Clinic in Roch-

ester has developed a unique practice, the

Women’s Heart Clinic, to treat and prevent

heart disease while addressing the distinct

concerns of women.

White House AppearanceSharonne Hayes, M.D., a Mayo Clinic

cardiologist and director of the Mayo Clinic

Women’s Heart Clinic, was a featured

speaker at an East Room event at the White

House in February 2005, and also joined the

First Lady at a recent cardiology conference.

For more information, go to

www.mayoclinic.org/cardiovascular-rst/

womensclinic.html

Women’s Heart Clinic

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Consultants, Continued

David L. Hayes, M.D.Sharonne N. Hayes, M.D.John A. Heit, M.D.David R. Holmes, M.D.Robert J. Houlihan, M.D. Allan S. Jaffe, M.D.Arshad Jahangir, M.D.Bruce D. Johnson, Ph.D.Donald L. Johnston, M.D.Ravi Kanagala, M.D.Birgit Kantor, M.D., Ph.D.Barry L. Karon, M.D.Lawrence R. Keenan, M.D.Kyle W. Klarich, M.D.Stephen L. Kopecky, M.D.Iftikhar J. Kullo, M.D.Sudhir S. Kushwaha, M.D.Andre C. Lapeyre, M.D.Hon-Chi Lee, M.D., Ph.D.Ami Lerman, M.D.Margaret A. Lloyd, M.D.Francisco Lopez-Jimenez, M.D.Youssef F. Malouf, M.D.Verghese Matthew, M.D.Robert D. McBane, M.D.Joseph P. PcConnell, Ph.D.Robert B. McCully, M.D.Michael D. McGoon, M.D.Ian R. McPhail, M.D.Michael S. Meyers, M.D.Fletcher A. Miller, Jr., M.D.Todd D. Miller, M.D.Wayne L. Miller, M.D., Ph.D.Andrew G. Moore, M.D.John F. Morrison, M.D.Sharon L. Mulvagh, M.D.Joseph G. Murphy, M.D.Thomas M. Munger, M.D.Rick A. Nishimura, M.D.Vuyisile T. Nkomo, M.D.Patrick W. O’Leary, M.D.Jae K. Oh, M.D.Lyle J. Olson, M.D.Timothy M. Olson, M.D.Steve R. Ommen, M.D.Michael J. Osborn, M.D.Douglas L. Packer, M.D.Patricia A. Pellikka, M.D.Sabrina S. Phillips, M.D.Co-burn Porter, M.D.Abhiram Prasad, M.B.B.S.Ganesh Raveendran, M.D.Robert F. Rea, M.D.Margaret M. Redeld, M.D.Guy S. Reeder, M.D.Charanjit S. Rihal, M.D.Richard J. Rodeheffer, M.D.Veronique L. Roger, M.D.Thom W. Rooke, M.D.Gurpreet Sandhu, M.D., Ph.D.Maurice E. Sarano, M.D.James B. Seward, M.D.Win-Kuang Shen, M.D.Roger F.J. Shepherd, M.D.Raymond C. Shields, M.D.Clarence Shub, M.D.

tutes of Health in many signicant ways. The Division’s training grant, “Cardiovasology,” is currently in its 30th year of continu-ous funding. This grant investigates the delicate balance between cardiac and vascular function and is led by Dr. Andre Terzic. Members of the Division of Cardiovascular Diseases hold 36 grants from the NIH, ranging from basic science of cardiac myocytes and vascular smooth muscle cells to the epidemiology of coronary dis-ease and heart failure. Notably, cardiovascular research takes place in nearly every building and hospital on the Rochester campus.

The Division of Cardiovascular Diseases has recently estab-lished the Cardiovascular Research Center to be housed within the Stabile building on the Mayo campus. This center will bring to-gether a critical mass of investigators with a focus on heart failure and atherosclerosis. Drs. John Burnett and Amir Lerman will lead this center. For clinical investigators, the Cardiovascular Research Unit represents the divisional effort to support clinical investiga-tion. The unit is a critical part of the coordinated fashion in which clinical trials operate at Mayo. n

Consultants, Continued

Robert D. Simari, M.D.Lawrence J. Sinak, M.D.Mandeep Singh, M.D.Hugh C. Smith, M.D.Virend K. Somers, M.D., Ph.D.Peter C. Spittell, M.D.Ray W. Squires, Ph.D.Vincent Tacyshyn, M.D.A. Jamil Tajik, M.D.Randal J. Thomas, M.D.R. Thomas Tilbury, M.D.Farris K. Timimi, M.D.Henry H. Ting, M.D.Teresa S.M. Tsang, M.D.Hector Villarraga, M.D.Carold A. Warnes, M.D.Paul W. Wennberg, M.D.Douglas L. Wood, M.D.R. Scott Wright, M.D.Waldemar E. Wysokinski, M.D.

Mayo Foundation Scholar

Martin Rodriguez-Porcel, M.D.

Specialists at Mayo Clinic have extensive experience evaluating, treating and counseling children and adults with long QT syndrome. Mayo Clinic has also been a leader in research related to identifying people who are at greatest risk for sudden death related to long QT syndrome.

For Kim Thomas, a physical education teacher who loves to work out, being active is a cen-tral part of her life. After being diagnosed with long QT syndrome, a rare and sometimes fatal disorder of the heart’s electrical system, Kim and her kids feared that they would no longer be able to enjoy their active lifestyles. But through a unique program at Mayo Clinic, they were able to resume their fast-paced lives.

Through genetic testing, Dr. Michael Ackerman, direc-tor of the Long QT Syndrome Clinic, determined that the Thomases’ type of long QT syndrome was tied to rest, not to exercise like the majority of those with the disease. Instead of needing to be on beta-blockers that reduced their physical capacity for exercise, they each received an implanted cardiac debrillator that monitors, and, if necessary, stops a potentially fatal heart rhythm. Kim and her family are thankful for Mayo Clinic’s unique resources for long QT syndrome. “Had it not been for genetic research and the care we’re receiving at Mayo Clinic, my children and I would not know what really causes our condition,” Kim says. n

To read more on long QT syndrome or the Thomases’ story, go to www.mayoclinic.org/long-qt-syndrome

Each year, Mayo Clinic specialists evaluate more than 300 patients with long QT syndrome, making Mayo one of the most experienced centers in the world. The Long QT Syndrome Clinic and Sudden Death Genomics Laboratory at Mayo Clinic in Rochester have one of the most com-prehensive programs internationally for families affected with this condition.

Patient Story – Long QT Syndrome at Mayo Clinic

Cardiovascular Diseases

Kim Thomas