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Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix Helena M. Cochemé, Caroline Quin, Stephen J. McQuaker, Filipe Cabreiro, Angela Logan, Tracy A. Prime, Irina Abakumova, Jigna V. Patel, Ian M. Fearnley, Andrew M. James, Carolyn M. Porteous, Robin A.J. Smith, Saima Saeed, Jane E. Carré, Mervyn Singer, David Gems, Richard C. Hartley, Linda Partridge, Michael P. Murphy Cell Metabolism Volume 13, Issue 3, Pages 340-350 (March 2011) DOI: 10.1016/j.cmet.2011.02.003 Copyright © 2011 Elsevier Inc. Terms and Conditions

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Figure 2 Cell Metabolism , DOI: ( /j.cmet ) Copyright © 2011 Elsevier Inc. Terms and Conditions Terms and Conditions

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Page 1: Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix Helena M. Cochemé,

Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix 

Helena M. Cochemé, Caroline Quin, Stephen J. McQuaker, Filipe Cabreiro, Angela Logan, Tracy A. Prime, Irina Abakumova, Jigna V. Patel, Ian M. Fearnley, Andrew M. James, Carolyn M. Porteous, Robin A.J. Smith, Saima Saeed, Jane E. Carré, Mervyn Singer, David

Gems, Richard C. Hartley, Linda Partridge, Michael P. Murphy 

Cell Metabolism Volume 13, Issue 3, Pages 340-350 (March 2011)

DOI: 10.1016/j.cmet.2011.02.003

Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 2: Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix Helena M. Cochemé,

Figure 1

Cell Metabolism 2011 13, 340-350DOI: (10.1016/j.cmet.2011.02.003) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 3: Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix Helena M. Cochemé,

Figure 2

Cell Metabolism 2011 13, 340-350DOI: (10.1016/j.cmet.2011.02.003) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 4: Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix Helena M. Cochemé,

Figure 3

Cell Metabolism 2011 13, 340-350DOI: (10.1016/j.cmet.2011.02.003) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 5: Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix Helena M. Cochemé,

Figure 4

Cell Metabolism 2011 13, 340-350DOI: (10.1016/j.cmet.2011.02.003) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 6: Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix Helena M. Cochemé,

Figure 5

Cell Metabolism 2011 13, 340-350DOI: (10.1016/j.cmet.2011.02.003) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 7: Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix Helena M. Cochemé,

Figure 6

Cell Metabolism 2011 13, 340-350DOI: (10.1016/j.cmet.2011.02.003) Copyright © 2011 Elsevier Inc. Terms and Conditions