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Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa Corporation [email protected]

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Page 1: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

Medication Therapy Management: Improving Health and Saving Money

July 23, 2008

Ed Staffa, RPh

Vice President, Pharmacy

Mirixa Corporation

[email protected]

Page 2: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

2Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

MTM At‐A‐Glance

The U.S. health care system uses a lot and spends a lot on medications

The benefits of all this use and cost are not maximized

Pharmacist‐delivered MTM can help overcome that challenge 

Page 3: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

3Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

In 2007 Retail Pharmacy Filled

3.52 Billion PrescriptionsUp from 3.42B in 2006

Source: NACDS www.nacds.org; Facts & Resources: IMS Health

Page 4: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

4Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Prescription Volume is Increasing

0

500

1,000

1,500

2,000

2,500

3,000

3,500

4,000

1992 1999 2001 2003 2005 2007

Source: IMS HEALTH and NACDS Economics Dept. 2005 prescriptions are projected.

Page 5: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

5Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

In 2007, the U.S. Health Care System Spent…

$259.4 Billionfor retail prescriptions in the US.

Up from $250.6  B, 2006

Source: NACDS www.nacds.org; Facts & Resources: IMS Health

Page 6: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

6Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Total Retail Prescription Drug Spending   (in millions of dollars)

$0

$50,000

$100,000

$150,000

$200,000

$250,000

$300,000

1990 1993 1996 1999 2002 2005

Source: IMS HEALTH and NACDS Economics Department.

Page 7: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

7Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Number of People Over 65

17 2026

3135

39

53

6975 79

01020304050607080

1960197019801990200020102020203020402050

Millions of people

Source: US Bureau of the Census Bureau. Aging in the United States: Past Present and Future

Page 8: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

8Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Average Prescription Prices 2007

$0.00$20.00$40.00$60.00$80.00

$100.00$120.00$140.00

1990

1992

1994

1996

1998

2000

2002

2005

Brand All Rx's Generic

Source: IMS HEALTH, NDCHealth, and NACDS Economics Department.

$119.51

$34.34

$69.61

Page 9: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

9Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

How Much Bang 

For the Buck?

Page 10: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

10Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

How is All this Medicine we Pay for Used?

World Health Organization Report (2003): 50% of patients in developed countries (including the U.S.) do not take their medication properly

30% of all refillable prescriptions in the U.S. are never refilled

17%‐20% of all new prescriptions in the U.S. are never filled

Marcus AD.  The Real Drug Problem: Forgetting to Take Them.  Wall Street Journal.  October 21, 2003.Improving Profits by Informing Patients. Dr. Dorothy L Smith’s Patient Education Update.  Source found on the World Wide Web. [http://www.consumer‐health.com/pharm/peu/peu_vol1_no1.htm]  Accessed 2003, Nov 14.NACDS Economics Department

Page 11: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

11Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Doctors Forget

“When initiating new medications, physicians often fail (up to 65% of the time) to 

communicate critical elements of medication use to the patient.”

David Geffen School of Medicine, UCLA, Independent Study

Archives of Internal Medicine. Vol. 166, Sept 25, 2006, pp. 1855-1862.

Page 12: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

12Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Patients Forget

Patients forget 80% of what their doctor tells them

Nearly half of what they remember, they remember incorrectly

Source: Journal of the Royal Society of Medicine, news release, May 1, 2003 

Page 13: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

13Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

U.S. Spends More on Medication Problems than the Actual Medications!

In 2000, the U.S. spent...

$144B on prescription medication

$177B on medication‐related problems

Source: Ernst FR, Grizzle AJ. Drug Related Morbidity and Mortality: Updating the Cost-of illness Model. Journal of the American Pharmaceutical Association. March/April 2001. Vol. 41 No. 2: 192-199.

Page 14: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

14Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

The Role of the Pharmacist

We’ve seen some challenges, 

now let’s see some solutions

Medication Therapy Management:

MTM

Page 15: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

15Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

MTM. What Is It?

Medicare Part D is ONE kind of MTM 

ALL Medicare Part D prescription drug plans must have an 

MTM program

Not ALL patients qualify

Multiple chronic conditions

Multiple medications

Likely to exceed $4K in Medicare Part D expenses

Plans have great flexibility in designing their MTM programs

Page 16: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

16Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Part D MTM

Wide open regulationsStill no widely accepted definition in Health Care

Huge numbers of PDPs and “MA‐PDs”450 PDPs, 1,200 MA‐PDs

Wide variety of delivery methodsMail, Telephone, Face to face

Wide variety of providersPharmacists, Nurses, Physicians, Others

Page 17: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

17Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

What is MTM?

APhA & NACDS Foundation

“Core Elements”of an MTM Service

(www.aphanet.org)

Version 1.0… April 2005Version 2.0… March 2008

Page 18: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

18Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

“Core Elements” of MTM

Medication Therapy Review

Personal Medication Record (PMR)

Medication Action Plan

Intervention and/or Referral

Documentation and Follow‐up

Page 19: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

19Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

MTM, Disease Mgmt

Formulary –Utilization

Mgmt

Compliance,Persistence,Patient Ed

Adverse Events

Tracking

ClinicalTrials/

Rx Alerts

Benefit Counseling

SpecialtyDrug

Services

Many Other Forms of “MTM” Besides Part D

All Forms of “MTM”

Page 20: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

20Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Importance of Having Opportunity to Interact with Your Pharmacist

68%

21%

11%

0%

10%

20%

30%

40%

50%

60%

70%

April '03 (n=1001)

7-10 [important]

4-6

1-3 [not important]

Study conducted by Wirthlin Worldwide for the National Association of Chain Drugs Stores Foundation

On a scale of 1 to 10 where 1=‘not at all important’ & 10=‘extremely important’

Page 21: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

21Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

The Asheville Project: (Asheville NC)

Overview of study activities:

• Employees with diabetes received one-on-one disease management counseling from pharmacists

• Sessions were held at regularly scheduled intervals in community pharmacy setting

• Employees were given free home testing equipment and diabetes medication

Absenteeism among diabetics

Note:  Estimated cost avoidance of each intervention is calculated using Bootman Johnson study. Source: Interviews with Outcomes Pharmaceutical Health Care; Journal of Managed Care Pharmacy

Total health care spending on diabetics

0

2,000

4,000

6,000

8,000

Previous Year First Year inprogram

$ PEPY overall healthcare spend

28% decrease

12.6

6

02468

101214

1996 2001

Days per year 52% decrease

Description of the study(per employee per year)

Size of group: 650 enrollees

Page 22: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

22Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Patient Self‐Management Program for Diabetes

Annual Cost Per Patient Before Program 

Annual Cost Per Patient After Program

Difference

MTM services $0 $351 +$351

Medication $3128 $3373 +$245

Medical $6254 $4740 ‐ $1514

Total ‐$918

Over one year, community pharmacists provide MTM services to diabetes patients in NC, GA, WI, OH (sponsored by self-insured employers).

Garrett, G., Bluml B., Patient Self‐Management Program for Diabetes: First Year Clinical, Humanistic, and Economic Outcomes; J Am Pharm Assoc., 2005;45:130‐137.

Page 23: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

23Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Nov. 14, 2006 JAMA Article:

Journal of the American Medical Association: November, 2006“Effect of Pharmacy Care Program on Medication Adherence and Persistence, 

Blood Pressure, and Low‐Density Lipoprotein Cholesterol”

Pharmacist‐centric study improved adherence to BP & lipid meds from 61.2% to 96.9%

Maintained 95.5% adherence 6 mo. after

Quote from Authors:“Underscores the value of pharmacists as key providers of patient counseling 

in correcting poor patient adherence.”

Simpson, RJ. Journal of the American Medical Association, Challenges for Improving Medication Adherence, November, 2006

Page 24: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

24Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

“The Minnesota Experience”: 12:1 ROI

Journal of the American Pharmacists Association: April, 2008“Clinical and Economic Outcomes of Medication Therapy Management Services: The 

Minnesota Experience”

285 chronically ill patients receive pharmacist‐delivered MTM Vs. 252 who do not

Result improved health and lower cost in MTM group12:1 Return on Investment

Isetts, et al. J Am Pharma Assoc. 2008: 48(2):203‐211

Page 25: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

25Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

State Medicaid MTM Initiatives

Virginia Healthy ReturnsIowa Pharmaceutical Case Management ProgramMaryland P3 Diabetes Disease Management ProgramMissouri Medicaid Pharmacy‐Assisted Collaborative Disease Management ProgramMinnesota Medicaid Medication Therapy Management ProgramNorth Carolina Lock‐in Program

Page 26: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

26Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

Take‐home Messages

MTM improves health and saves money

Support MTM initiatives in YOUR state

Page 27: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

27Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

All data shown is fictitious and any resemblance to a real person is purely coincidental.

Page 28: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

28Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

All data shown is fictitious and any resemblance to a real person is purely coincidental.

Page 29: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

29Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

All data shown is fictitious and any resemblance to a real person is purely coincidental.

Page 30: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

30Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

All data shown is fictitious and any resemblance to a real person is purely coincidental.

Page 31: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

31Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

All data shown is fictitious and any resemblance to a real person is purely coincidental.

Page 32: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

32Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

All data shown is fictitious and any resemblance to a real person is purely coincidental.

Page 33: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

33Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

All data shown is fictitious and any resemblance to a real person is purely coincidental.

Page 34: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

34Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

All data shown is fictitious and any resemblance to a real person is purely coincidental.

Page 35: Medication Therapy Management: Improving Health and … · Medication Therapy Management: Improving Health and Saving Money July 23, 2008 Ed Staffa, RPh Vice President, Pharmacy Mirixa

35Confidential © 2008 Mirixa Corporation 

www.Mirixa.com

All data shown is fictitious and any resemblance to a real person is purely coincidental.