Medicine and

Engineering at Duke

Motivation: SOM and Pratt

Common Goals

Clinical Medicine

Basic Science

Engineering

HEALTH & DISEASE

Diagnostics & > Therapy

Entrepreneurship >

& Policy

Enabling > Research

ENHANCING EDUCATION ADVANCING

TRANSLATION

IMPROVING HEALTH

• Top 10 medical school and top-tier hospitals

• Top 10 BME program + fastest-rising engineering school

(Top 20 UG, Top 30 grad)

• $20M Duke-Coulter Translational Partnership

• Strong clinical, research & IT infrastructure

• Interdisciplinary hubs: DGHI, iiD, DTRI, I&E, DIBS

• Physical proximity & culture of collaboration

The Duke Advantage: Key Assets

MEDx Reflections

Leadership

SOM

• Hashim Al-Hashimi

(Biochemistry)

• Ben Alman (Orthopedics)

• Patrick Codd (Neurosurgery)

• Allan Kirk (Surgery)

• Mary Klotman (Medicine)

• Steve Lisberger

(Neurobiology)

Pratt

• Tosh Chilkoti (BME)

• Chris Dwyer (ECE)

• Claudia Gunsch (CEE)

• George Truskey (BME)

• Jennifer West (BME/MEMS)

• Pei Zhong (MEMS)

Associate Director – Ken Gall PhD (MEMS Chair)

1. Innovative and affordable and effective diagnostics

and devices

2. Data science, signal processing and predictive

modeling

3. Robotics-enabled basic science and clinical

procedures

4. Tissue engineering and regeneration

5. Brain science and neuro-engineering

Initial Strategic Themes

Weekly MEDx Café

• Weds AMs at Twinnie’s and Nosh

• Drop-in opportunities for students and faculty

MEDx Lunch

• Student-Student or Student-Faculty lunches to discuss

collaborative research opportunities

Social Engineering

First Inter-school Colloquia

• “Duke Surgical Robotics” – Patrick Codd (Neurosurgery) and Kris Hauser (ECE)

• “Challenges Seeking Solutions in Primary Care, Cancer and Engineering” – Sharon Hull (Community and Family Medicine) and Nimmi Ramanujam (BME)

• “Bringing Neuro-engineering to the Clinic” – Nandan Lad (Neurology) and Craig Henriquez (BME)

• “Fluid Dynamics in Virtual 3D Models of Cardiac Defects in Children” – Piers Barker (Pediatrics) and Amanda Randles (BME)

• “Microbiome Synthesis” – John Rawls (MGM), Lawrence David (MGM) and Claudia Gunsch (CEE)

• “Mobile and Wireless Technologies” – Ryan Shaw (School of Nursing) and Tuan Vo-Dinh (BME)

New Interschool Colloquia

Research Pilot Program RFAs ($50,000 awards)

1. VPR - Collaborative Quantitative Approaches to Problems in the Basic and

Clinical Sciences (8 applications funded)

• targeted to enhance interactions between faculty in the Campus departments and

groups within the School of Medicine (SoM), with applications at the intersection of

quantitative science and medicine

2. MEDx Interschool Collaborative Pilot Program (30 Applications Received)

• targeted to enhance collaborations between the School of Medicine and Pratt faculty

in the area of diagnostics and devices.

• Syndicate with MEDx Leading: Surgery, Medicine, Orthopedics, Neurosurgery, DIHI,

CTSA, MEMS

Seed Funding

• Rapid, non-invasive, point-of-care cancer diagnostic tool

Brant Inman (Surgery) and Jeff Glass (ECE)

• Devices for improved tendon to bone healing

Shalini Ramasunder, MD (Ortho) and Jennifer West (BME/MEMS)

• A novel catheter for treatment of hydrocephaly

Nandan Lad (NeuroSurg) and Ken Gall (MEMS)

• A micro-physiologic system to test the tumorigenic behaviors and drug responses of

skeletal muscle tumors

Corinne Linardic (Peds) and Nenad Bursac (BME)

• High intensity forced ultrasound and immunotherapeutic intervention for destruction

of tumor cells

Kim Lyerly (Surgery) and Pei Zhong (MEMS)

• A miniaturized apheresis device for research and pediatric use

Gow Arepally (Medicine), Neal Simmons and Hadley Cocks (MEMS)

Diagnostics and Devices

4 Teams (expanding to 8 teams 2017)

• Dunson – models of intraoperative blood pressure as predictors of post-op renal function

• Hauser – intraoperative patient trajectories for optimizing therapy and reducing adverse events

• Heller – machine learning to manage surgical outcomes

• Rai – use of EHR data for scalable framework for diabetes management

Data Science: MEDx-iiD-Accenture

Discovery

Research

Discovery

Research

Translational

Research

Discovery

Research

Translational

Research Commercialization

• Integration at the student level

– Undergrad, post doc programs

• Integration of faculty

– Interschool colloquia

– Seed funding

• Shadowing

– “Engineers in scrubs”

– “InnovateMD”

• Joint hires RFP

Strategic Priorities

• Coulter enhancements

• Engaging the basic science community

• Collision space

– Fitzpatrick CIEMAS, Downtown

– Telecom – Innovation Co-Lab

– DUSON – Simulation Lab

• Gateway to campus talent

• Thematic center grants

Strategic Priorities

• Dean Andrews, Deans Katsouleas, Truskey and

Bellamkonda

• Provost Kornbluth

• Donors

– Dr. Mike Ramsey

– Pamela Rosenau

– The Julius H. Caplan Charity Foundation

Thank You