medicine at the benchtop and the bedside: course guidelines robert h. chow, md phd usc-caltech...
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![Page 1: Medicine at the Benchtop and the Bedside: Course Guidelines Robert H. Chow, MD PhD USC-Caltech MD-PhD Program Keck School of Medicine](https://reader036.vdocument.in/reader036/viewer/2022081511/56649d4b5503460f94a2858d/html5/thumbnails/1.jpg)
Medicine at the Benchtop and the Bedside: Course Guidelines
Robert H. Chow, MD PhD
USC-Caltech MD-PhD Program
Keck School of Medicine
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• Seminar course for MD-PhD students• Purpose:
– to introduce a clinical problem and research related to that problem– to introduce the faculty and their research – to keep your mind active and curious during the
first two years of med school!
• Two students present – 2nd-yr student presents clinical problem– 1st-yr student presents research paper
• One or two faculty mentors
Medicine at the Benchtop and the Bedside
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Friday, September 25, 2009Faculty facilitator: Dr. Robert ChowStudent facilitator: none
Friday, October 16, 2009Faculty facilitator/s: Dr. James Weiland and Dr. Rajat AgrawalStudent facilitators: TBA
Friday, October 23, 2009Faculty facilitator/s: Dr. Peter Jones and TBAStudent facilitators: TBA
Friday, October 30, 2009Faculty facilitator/s: Dr. Ellis Meng and Dr. Uttam SinhaStudent facilitators: TBA
Friday, November 20, 2009Faculty facilitator/s: Dr. Shelly Lu and TBAStudent facilitators: TBA
Friday, December 4, 2009Faculty facilitator/s: Dr. Andrea Armani and Dr. Jane EmersonStudent facilitators: TBA
Tentative Outline
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Following this slide are two sets of slides which can serve as templates
for the student presentations
• The mentor(s) may decide that an alternative format is preferable, in which case follow the mentors’ guidelines
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Template for Clinical PresentationFor Medicine at the Benchtop
and Bedside
Robert H. Chow
Zilkha Neurogenetic Institute
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History of
• if there are juicy tidbits about the history of this clinical problem or the research…
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Case Presentation
• Chief complaint
• History of presenting illness
• Physical Examination
• Pertinent laboratory findings
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Clinical Presentation: Symptoms/Signs
• What is difference between a symptom and a sign?
• In detail, typical presenting symptoms and signs
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Diagnosis
• Pathognomonic signs/symptoms
• Lab tests
• Possible springboard for the research part of this seminar
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Differential Diagnosis• Here, you list and discuss other diagnoses
that should be considered for the presenting signs/symptoms
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Natural history
• The clinical course of the disease/ illness when no treatment is given
• Possible springboard for research portion of seminar
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Epidemiology
• Characteristics at population level
• Possible springboard for research portion of seminar
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Etiology/Pathogenesis
• May review pertinent anatomy/ physiology here
• Possible springboard for the research part of this seminar
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Therapy/Response
• Current approach to therapy
• Scientific basis of therapy (or lack thereof !) -- another springboard for the reseach part of the seminar
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Other interesting aspects of the clinical problem
• Clinically relevant offshoots…
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Template for Research Paper Presentation For Medicine at the Benchtop and Bedside
Robert H. Chow
Zilkha Neurogenetic Institute
![Page 17: Medicine at the Benchtop and the Bedside: Course Guidelines Robert H. Chow, MD PhD USC-Caltech MD-PhD Program Keck School of Medicine](https://reader036.vdocument.in/reader036/viewer/2022081511/56649d4b5503460f94a2858d/html5/thumbnails/17.jpg)
Title of Article
Authors (at least the first and last)
Institutional Affiliation(s)
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Major Hypothesis or Question
• Subhypothesis/ subquestion 1
• Subhypothesis/ subquestion 2
• Etc.
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Background
• Short rationale or history of study of this hypothesis
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Preparation
• Which animal/ tissue/ cell type used for the study• Any relevant details about the preparation,
particularly justification for using this preparation
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Materials and Methods
• Method(s) used to perform study• Approach to analysis
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Result 1
• Usually a figure clipped from paper
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Result 2
• Another figure…
• It’s not necessary to review every figure in the paper, just the ones you want to focus on
• Etc.
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Author’s Conclusions
• Summarize what the authors state is the important conclusion(s) of the paper
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Critique of Paper
• Similar to review of submitted manuscript or grant proposal
• Evaluate the paper:– Author’s expertise– Validity of approach/ model/ methods– Quality of data– Validity of analysis– Validity of conclusions– Thoughts on how the study might have been improved--------------------------------------------------------------– Ideas on how to follow up on the findings of the paper…