michelle - hypertension of metabolic syndrome and relation to cvs

5
HYPERTENSION

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Page 1: Michelle - Hypertension of Metabolic Syndrome and Relation to CVS

HYPERTENSION

Page 2: Michelle - Hypertension of Metabolic Syndrome and Relation to CVS

High blood pressure

Having blood pressure of 135/85 mm Hg or greater

 a person in hypertensive crisis may experience:

1. Severe headaches

2. Severe anxiety

3. Shortness of breath

4. Nosebleeds

Page 3: Michelle - Hypertension of Metabolic Syndrome and Relation to CVS

Increase in visceral fat

stores

Increase in portal

FFA

Decrease in hepatic insulin

clearance

Increase in plasma insulin

Increase in renal sodium reabsorption

HypertensionAngiotensinogen

Angiotensin I

Angiotensin II

Vascular constriction

Page 4: Michelle - Hypertension of Metabolic Syndrome and Relation to CVS

RELATION OF METABOLIC SYNDROME TO

CARDIOVASCULAR DISEASE

Page 5: Michelle - Hypertension of Metabolic Syndrome and Relation to CVS

Dyslipidaemia Hypertension Obesity

Oxidative stress

Endothelial stress

Decrease in nitric oxide, increase in local mediators,

increase in tissue ACE-A

Thrombosis, inflammation, vasoconstriction, vascular

lesion and remodeling, plaque rupture

Risk factors