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V.1.0

Operation Manual

Model MDB-1000

MICRO DRY BATH

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CONTENTS 1. Safety 3 2. Instruction 6 3. Package contents 6 4. Features 6 5. Applications 6 7. Specifications 7 8. Accessories 7 9. Parts of the Micro dry bath 8 7. Installation Instruction 9 8. Operating 9 9. Temperature calibration 10 10. Power recover function 11 11. Trouble shooting 11 12. Maintenance 12 13. Warranty statement 12

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１．Safety This HARMONY Micro Dry Bath has been tested and found to comply with safety limits for the CE regulation. Also, the block water bath is RoHS compliant to deliver confident product which meets the environmental directive. These limits are designed to provide reasonable protection against harmful interference when the equipment is operated in a commercial environment. This equipment generates, uses, and can radiate radio frequency energy, and if not installed and used in accordance with the instruction manual, may cause harmful interference to radio communications. Operation of this equipment in a residential area is likely to cause harmful interference in which case the user will be required to correct the interference at their expense. Changes or modifications not expressly approved by the party responsible for compliance could void the user’s authority to operate the equipment. It is strongly recommended for the user to read the following points carefully before operating this equipment. ☞ Read the manual before using the Block Water Bath.

Improper handling may cause a serious hazard, resulting in personnel injury or death.

Improper handling may cause a serious hazard resulting in personnel injury or damage to equipment or buildings.

☞ Meanings of symbols.

Caution / Warning.

Refrain from doing this.

Follow all Instructions.

Do Not Touch.

Do not alter the equipment. Failure to follow these directions could result in personal and/or laboratory hazards, as well as invalidate device warranty.

Use a properly grounded electrical outlet with correct voltage and current handing capacity.

Disconnect from power supply plug if the unit is not going to be used for an extended period of time and before maintenance and servicing. Refer serving to qualified personal.

Insert the plug securely into a wall socket. Loose connections result in excessive heat generation to the device and may cause arcing to occur at the connection.

Before operation, ensure that the power cord is fully extended. Keep the cord away from heat sources and do not place any objects on any part of the cord.

Avoid using multi-point extension power cords.

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Never use this instrument series without having the safety cover correctly in position.

Do not use the unit if there is any sign of damage to the external tank or cover. Replace damage part.

Do not use in the presence of flammable or combustible material; fire or explosion may result. This equipment contains components which may ignite such materials.

Ensure that the system is connected to electrical service according to local and national electrical codes. Failure to properly connection may create fire or shock hazard.

Use appropriate materials and operate correctly to avoid possible hazards of explosion implosion or release of toxic or flammable gases arising from overheated materials.

Always use the block lifter to remove hot blocks, and wear appropriate protection to avoid burning your hand. ATTENTION: Hot Surface!

The unit shall be operated only by qualified personnel.

☞ Installing the device

Place the block water bath on a level, horizontal surface. Ensure that the device sits completely on a worktop.

Do not install the device where it can get damp or wet.

Do not use the device in potentially explosive atmosphere.

Do not operate the device in rooms where work is being carried out with explosive substances.

Do not use the device to process any substances which could create an explosive atmosphere

Do not use the device near a heat source or where temperatures are elevated. Do not operate the device when temperatures ambient to 40oC.

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☞ Installing the device

Do not use the power supply when signs of damage are evident, and particularly if the power cable is damaged.

Only connect the power supply to voltage sources that correspond to the information on the identification plate regarding the power supply.

Do not use this device where there are flammable or corrosive vapors.

Install the device in a well-ventilated place. Insufficient ventilation may result in breakdown should there be overheating.

☞ Operating the device

Do not operate the device before reading and fully understanding all instructions in this manual.

Observe the national regulations for handling these substances as well as the material safety data sheets and manufacturer’s application notes.

This device is not designed to be user serviceable. Do not attempt to open or modify the device. Should be device be opened by unauthorized personnel, all warranties are void.

Should there be any abnormal smell, or noise during operation, switch off the device immediately and contact your dealer for service.

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Only use accessories and original spare parts recommended by manufacturer.

Only initiate dispensing if it is safe to do so.

Do not use the device to process samples with flammable contents. This unit is not designed to be explosion-proof.

For all dispensing tasks, make sure that you are not endangering yourself or anyone else.

After operation, clean the device and unplug the power if it will not be used for extended periods.

2. Introduction Thank you very much for purchasing the HARMONY Micro Dry Bath MDB-1000. Your Micro dry bath is CE Certified and designed with function, reliability, and safety in mind. For safe operation, please pay attention to the alert symbols throughout the manual.

3. Package Contents Micro Dry Bath 1 unit Lid for Micro dry bath 1 ea Power Plug 1 ea Power Adapter 1 ea Operation Manual 1 ea

4. Features

• Microprocessor controller with digital display • Rapid temperature increase rate • Easy user temperature calibration • PTFE-coated aluminum alloy heating chamber • Single block mode.

5. Applications Restriction enzyme digestion, denaturing DNA, Blood Urea Nitrogen, melting agar, coagulation studies, hybridization, and Hot Start thermo-cycled reaction, etc.

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6. Specifications Controller Digital microprocessor controller Display LED Display Heating Power 50W Power Rating AC input : 100-240V~, 2A, 50/60 Hz

DC input: +12V/5A, 60W max. Temperature Control Range (Dry Bath)

5°C above ambient to 100°C

Temperature Control Range (Water Bath)

5°C above ambient to 90°C

Temperature Increment 0.1°C Temperature Calibration Yes Temperature Uniformity@37°C ± 0.2°C Temperature Accuracy@37°C ± 0.25°C Timer 1 min - 99hrs 59min, continuous Safety Device Leakage proof for heating chamber

Over temperature protection SSR failure detection

Environment Temperature for operation Ambient - 40°C, ≤95% RH Heating Chamber Material Molded aluminum alloy chamber

(PTFE-Coated) Block Material Aluminum Block Type Standard and customized are available Rated Voltages 110V~ or 220V~; 50/60Hz

Unit Dimension 153 x 125 x 65 mm (W x L x H) Weight approx.0.6

7. Accessories

Cat. No. Description MDB-1000 Micro Dry Bath without block ACCESSORIES MDB1000-01 For 0.2ml tube(PCR Strip tube), ø 6.35mm, 32 wells,

L71xW47xH32, Depth 19mm MDB1000-02 For 1.5ml tube, ø 10.8mm, 12 wells, L71xW47xH32mm,

Depth 28.5mm MDB1000-03 For 15ml tube, ø 17.3mm, 6 wells, L71xW47xH75mm,

Depth 70mm MDB1000-04 For 50ml tube, ø 29.2mm, 2 wells, L71xW47xH75mm,

Depth 72mm MDB1000-05 For 0.5ml tube, ø 8.0mm, 12 wells, L71xW47xH32mm,

Depth 25mm MDB1000-06 For 2.0ml or 1.5ml tube, ø 11.0mm, 12 wells,

L71xW47xH32mm, Depth 30mm MDB1000-07 For 2.0ml or 1.5ml tube, ø 10.9mm, 12 wells,

L71xW47xH32mm, Depth 30mm MDB1000-L Block lifter 95mm, with E-Type Retaining Rings MDB1000-CAR-ADAPTER Car Adapter for MD-MINI, 1.5m MDB1000-LID MD-MINI Lid, 58.5x83x31.5mm

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8. Parts of the Micro Dry Bath

Fig.1 Front View

Fig.2 Rear View

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① Key – to increase temperature or time value

② Key – to decrease temperature or time value

③ Key – to start or stop the program

④ Key – switch between temp or timer mode

⑤ Temp – This LED lights up when the unit is operating under temperature setting mode.

⑥ Time – This LED lights up when the unit is operating under the Timer Mode

⑦ Heating –This LED light indicates the temperature is increasing.

⑧ LED Display

⑨ PTFE-coated chamber

⑩ Power Switch – to switch the unit power ON/OFF

⑪ DC Power Socket

⑫ Block lift holder

9. Installation Instruction

The unit is actually a pre-installed instrument. As long as it is placed on a sturdy and level surface in a safe, dry place, and is inserted with one or two heating aluminum block(s) or simply water as a water bath, it is ready for operation.

8. Operating

Fig.3 Control Panel

8-1. Place Micro Dry Bath on a sturdy and leveled surface in a safe, dry place, away from laboratory traffic. 8-2. Ensure that the power switch is OFF, then plug the three-pronged power cord into a grounded three-prong

AC outlet of the appropriate voltage.

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8-3. Select suitable module block or appropriate water volume and put it / them into the Micro Dry Bath. 8-4. Turn the DC power ON. 8-5. Run temperature calibration procedure when using the instrument for the first time (see page 10). 8-6. Press ①”Up” and ②”Down” Key to adjust to the desired temperature. 8-7. To set the timer for the heating process, press ④”Mode” Key, and then press ①”Up” and ②”Down” Key to

adjust timer upon your request. The unit will stop with alarm when timer is up. 8-8. Press the ③”Start/Stop” Key to start heating. 8-9. To reset timer during heating, simply press ③”Start/Stop”Key to deactivate heating. 8-10. Press ③”Start/Stop” Key again to start the heating after setting.

Note: Please do not use Lid in water bath mode.

9. Temperature Calibration

The Micro Dry Bath with the optional block has been calibrated as a set. However, different block types or

different water source may have different influences and may cause different results. For optimum accurate

temperature control, or while changing with different kinds of block or water, The Micro Dry Bath should be

calibrated in accordance with the procedure outlined below.

9-1. Insert a calibrated laboratory thermometer into the thermometer holding port, which is located on the block

or in the middle of the chamber when water is filled.

2. Press and hold the ③“Start/Stop” Key while switching the main power ON. The Micro Dry Bath will beep and

the LED display will start flashing. This indicates the unit is under the Calibration Mode.

This segment will be flashing.

3. Press ①”Up” and ②”Down” Key to adjust display value to the temperature you want to control accurately,

and then press ③“Start/Stop” Key.

4. As the unit reaches the Target Temperature, the timer will be start to count down. Wait for approximately 30

mins, you should be hearing the “beeping” sound.

5. Adjust the display value according to the value as thermometer. And then press ③“Start/Stop” Key, the

screen will display as follow.

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Saving the calibrate value

6. The calibrated procedure is now finished. Please wait for a few more minutes for the microprocessor to

automatically adjust displayed temperature value to the same value with thermometer measured.

10. Power Recover Function

1. If MD-mini was turned off during the heating state and then turned back on again. It will buzz and display

countdown from 10 to 0, then it will recover back to the last state. The timer will resume from last state as

well.

2. Press the during the countdown period to terminate the buzz and the timer. MD-mini is then

ready for operating.

10. Trouble Shooting

Trouble The Cause of trouble Trouble Shooting

Alarms with short buzz sound.

Overheating:

When the current temperature reaches above 5 degrees than the set value.

System will automatically return to normal

Alarms with long buzz sound.

Overheating:

When the temperature reaches above 110° C.

Restart the unit.

If AL1 and Er1 occur simultaneously, Restart the unit as Er1 takes priority. If problem persist, please contact Major Science for immediate assistance.

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Alarms with long buzz sound.

Micro Dry Bath temperature sensor is abnormal,

Restart the unit. If problem persist, please contact Major Science for immediate assistance.

LED does not light up

Check Electric Supply Check fuse Check Heater Indicator Light

Plug is firmly inserted into the electrical socket Electrical Power is turned on Replace fuse Replace PCB Assembly

11. Maintenance

Cleaning ・ The rotor and outside of the centrifuge should be cleaned regularly with a damp cloth. ・ Disconnect the centrifuge from the main supply before the cleaning. ・ Only neutral agents or a mild liquid soap may be used. ・ Do not use chemical cleaning agents or strong solvents. ・

Mechanical or chemical damage ・ Do not operate the centrifuge when there is mechanical or chemical damage. ・ Change faulty parts immediately.

13. Warranty Statement The warranty for the device is 12 months from the date of purchase. During this period the device will be repaired or exchanged without charge. Warranty is void on devices with damaged manufacture’s number, damaged seal, or damage due to improper use, storage or transport of device or service by unauthorized persons.

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Date of sale Product

Name

Micro Dry Bath

Model No. MDB-1000 Serial No.

User Name Division

Address 〒

TEL:

Warranty Period One year from the date of purchase

Distributor Name

Address TEL

Responsible Party Signature

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Tanaka Bldg., 3-6-7, Hongo, Bunkyo-Ku, Tokyo113-0033

Tel: +813-5842-4171 Fax: +813-3818-7095