Microarrays for the Masses: Pedagogical Resources for High School through CollegeA. Malcolm Campbell1,3, Laurie J. Heyer2,3, Mary Lee S. Ledbetter4,3, Laura L. M. Hoopes5,3, Todd T. Eckdahl6,3, Anne G. Rosenwald7,3, Edison Fowlks8,3, Nicholas Dovidio2,

Michael R. Gordon2, David Moskowitz2, Mackenzie L. Cowell1, J. Adam Abele2, Brian Akin2, Gavin Taylor2, Danielle Choi1, Parul Karnik2, Peter Lowry1, Jennifer M. Madden1, Emily E. Oldham1,2, B. Daniel Pierce1, Allison Amore1, Sheena Bossie1, Max Citrin1, Erin Cobain1, Megan McDonald1, Marieta Solé1, Emily Wilson1, Matt Gemberling1, Kristen DeCelle1, Karen Acker1, Lyana Buckwold1, Benjamin Whigham1, Carolyn A. Zanta9, Kathleen M. Gabric10, Ben Kittinger1, Lesli Adler11, A. Jackie Ryan1, William T. Hatfield1,2.

1Biology Department, 2Mathematics Department, Davidson College; 3Genome Consortium for Active Teaching (GCAT), 4Department of Biology, College of the Holy Cross, Worcester, MA; 5Department of Biology, Pomona College, Claremont, CA; 6Department of Biology, Missouri Western State University, Saint Joseph, MO; 7Department of Biology, Georgetown University, Washington, DC; 8Department of Biology, Hampton University, Hampton, VA, 9Howard Hughes Medical Institute Biotechnology Education and Outreach Program, University of Illinois at Urbana-Champaign, Urbana, IL; 10Hinsdale Central High School, Hinsdale, IL; and 11Montgomery County Public Schools, Rockville, MD.

Wet Lab Simulation & Math Module

Open Access Animations & Online Clustering

Online Spot Synthesizer Research Protocols and Chips

Thanks to NSF, HHMI, Davidson College, the Waksman Foundation,the James G. Martin Genomics Program, and the Associated Colleges of the South.

Do-It-Yourself Teaching Chips

MAGIC Tool Software

#1741

Top animation is 3 minutes long, bottom one is 30 minutes with interactive questions.

Interactive clustering site allows students to explore how clustering works.

http://gcat.davidson.edu/Pirelli/index.htm http://gcat.davidson.edu/DGPB/clust/clustering.htm

Introductory Curriculum with paper exercise, wet lab simulation is modular and flexible, based on cancer case study.

Mathematics module allows students to use math to understand method and basic biology.

www.bio.davidson.edu/projects/GCAT/HSChips/HSchips.html

Upload spreadsheet, select pattern, and produce tiff files for training and testing student proficiency.

www.bio.davidson.edu/projects/GCAT/Spot_synthesizer/Spot_synthesizer.html

www.bio.davidson.edu/MAGIC

www.bio.davidson.edu/projects/GCAT/DoItYourselfChips/Self_Chips.html

www.bio.davidson.edu/GCAT

www.bio.davidson.edu/courses/genomics/chip/chip.html

Improved display methods, gridding, spot flagging, statistical analysis, and JTreeView connectivity

GCAT supports faculty by providing microarrays (HHMI funded) and hands-on, free workshops (NSF funded).

Students can design and print their own mini-chips with near 100% success.

2007 workshop participants and one of the their chips. Workshop in 2008 is full and 2009

workshop will accept applications in 2008.

macampbell@davidson.edu http://gcat.davidson.edu/masses.html