Micro-Encapsulation

Prepared ByAjay Chavan

MICRO-ENCAPSULATION

Micro - (Small) Encapsulation -(Capsule formation)

It Is defined as the applying relatively thin coating to small particles of solids or droplets of liquids and dispersions.

Coating size Range:– 100 – 5000Micron

Advantages of Micro-Encapusulation over Tablet Coating

Micro-Encapsulation• Converting liquid into

flowable solids• Alters colloidal and

surface properties• Smallness of coating size• Adaption to wide variety

of dosage form• Distribution widely

throughout GIT• Drug absorption is more

Tablet Coating• Solid to solid only• Coating size large

incase of suger coating

• Adapt only over tablet• Distribution is slow• Drug absorption is

slow compare to Micro-Encapsulation

Disadvantages of Micro-Encapsulation• No single microencapsulation process is

adaptable to all core material candidates or product application

• Non reproducible• Economic limitations

Application Of Micro-Encapsulation (SSC)

• Stabilization of core material• Sepration of chemically reactive

ingridients• Control of Release of core

materials

Types of Micro-Encapsulation Process

1.Air Suspension2.Coacervation– phase

Separation3.Spray Dryimg4.Polymerization 5.Pan Coating

SummaryWhat is microencapsulation?Advantages and DisadvantagesApplicationsTyeps of Processes.

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