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MINI-MEDICAL SCHOOL My Aching Neck – My Aching Back Mario De Pinto, MD Department of Anesthesiology and Perioperative Care Pain Management Center March 10, 2016

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Page 1: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

MINI-MEDICAL SCHOOL

My Aching Neck ndash My Aching Back

Mario De Pinto MD Department of Anesthesiology and Perioperative Care

Pain Management Center

March 10 2016

NO DISCLOSURES

OBJECTIVES

Epidemiology ndash Risk Factors

Sources and Causes of Neck and Low Back Pain

Short and Long Term Management

DEFINITIONS

NECK PAIN (NP)

Pain in the neck withwithout pain referred into one or both upper extremities

In some cases pain may be associated with headaches

LOW BACK PAIN (LBP)

Pain on the posterior aspect of the body

from the lower margin of the 12th rib to the lower gluteal folds withwithout pain referred into one or both extremities

EPIDEMIOLOGY

NECK PAIN - PREVALENCE

Global point prevalence in 2010 - 49 Peaks at a young age - 45 years

Higher in females ndash 58 vs 40

LOW BACK PAIN

Global point prevalence in 2010 ndash 94 Higher in males 101 vs 87 Peaks at approx 80 years of age

Prevalence total number of

cases of a disease in a given

population at a specific time

MSK pain reported by 521 of persons aged 18 years and older in 2012

LBP most common (286) NP third most common (152)

(Knee pain second most common at 181)

Females report MSK pain more frequently than males (546 vs

495) The prevalence of LBP and NP highest

for persons age 45 to 64 years

MUSCULOSKELETAL (MSK) DISORDERS ndash US DATA

About half (496)of the total disability burden associated

with MSK disorders is from LBP

NP (201) also caused

substantial disability burden

Between 1998-2011 total direct and indirect costs of

musculoskeletal conditions rose from $3961 billion to $8738

billion ( 121)

Over the same period of time the US Gross Domestic Product

(GDP) has risen from $115 trillion to $152 trillion ( 32)

MUSCULOSKELETAL (MSK) DISORDERS - COST

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 2: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

NO DISCLOSURES

OBJECTIVES

Epidemiology ndash Risk Factors

Sources and Causes of Neck and Low Back Pain

Short and Long Term Management

DEFINITIONS

NECK PAIN (NP)

Pain in the neck withwithout pain referred into one or both upper extremities

In some cases pain may be associated with headaches

LOW BACK PAIN (LBP)

Pain on the posterior aspect of the body

from the lower margin of the 12th rib to the lower gluteal folds withwithout pain referred into one or both extremities

EPIDEMIOLOGY

NECK PAIN - PREVALENCE

Global point prevalence in 2010 - 49 Peaks at a young age - 45 years

Higher in females ndash 58 vs 40

LOW BACK PAIN

Global point prevalence in 2010 ndash 94 Higher in males 101 vs 87 Peaks at approx 80 years of age

Prevalence total number of

cases of a disease in a given

population at a specific time

MSK pain reported by 521 of persons aged 18 years and older in 2012

LBP most common (286) NP third most common (152)

(Knee pain second most common at 181)

Females report MSK pain more frequently than males (546 vs

495) The prevalence of LBP and NP highest

for persons age 45 to 64 years

MUSCULOSKELETAL (MSK) DISORDERS ndash US DATA

About half (496)of the total disability burden associated

with MSK disorders is from LBP

NP (201) also caused

substantial disability burden

Between 1998-2011 total direct and indirect costs of

musculoskeletal conditions rose from $3961 billion to $8738

billion ( 121)

Over the same period of time the US Gross Domestic Product

(GDP) has risen from $115 trillion to $152 trillion ( 32)

MUSCULOSKELETAL (MSK) DISORDERS - COST

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 3: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

OBJECTIVES

Epidemiology ndash Risk Factors

Sources and Causes of Neck and Low Back Pain

Short and Long Term Management

DEFINITIONS

NECK PAIN (NP)

Pain in the neck withwithout pain referred into one or both upper extremities

In some cases pain may be associated with headaches

LOW BACK PAIN (LBP)

Pain on the posterior aspect of the body

from the lower margin of the 12th rib to the lower gluteal folds withwithout pain referred into one or both extremities

EPIDEMIOLOGY

NECK PAIN - PREVALENCE

Global point prevalence in 2010 - 49 Peaks at a young age - 45 years

Higher in females ndash 58 vs 40

LOW BACK PAIN

Global point prevalence in 2010 ndash 94 Higher in males 101 vs 87 Peaks at approx 80 years of age

Prevalence total number of

cases of a disease in a given

population at a specific time

MSK pain reported by 521 of persons aged 18 years and older in 2012

LBP most common (286) NP third most common (152)

(Knee pain second most common at 181)

Females report MSK pain more frequently than males (546 vs

495) The prevalence of LBP and NP highest

for persons age 45 to 64 years

MUSCULOSKELETAL (MSK) DISORDERS ndash US DATA

About half (496)of the total disability burden associated

with MSK disorders is from LBP

NP (201) also caused

substantial disability burden

Between 1998-2011 total direct and indirect costs of

musculoskeletal conditions rose from $3961 billion to $8738

billion ( 121)

Over the same period of time the US Gross Domestic Product

(GDP) has risen from $115 trillion to $152 trillion ( 32)

MUSCULOSKELETAL (MSK) DISORDERS - COST

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 4: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

DEFINITIONS

NECK PAIN (NP)

Pain in the neck withwithout pain referred into one or both upper extremities

In some cases pain may be associated with headaches

LOW BACK PAIN (LBP)

Pain on the posterior aspect of the body

from the lower margin of the 12th rib to the lower gluteal folds withwithout pain referred into one or both extremities

EPIDEMIOLOGY

NECK PAIN - PREVALENCE

Global point prevalence in 2010 - 49 Peaks at a young age - 45 years

Higher in females ndash 58 vs 40

LOW BACK PAIN

Global point prevalence in 2010 ndash 94 Higher in males 101 vs 87 Peaks at approx 80 years of age

Prevalence total number of

cases of a disease in a given

population at a specific time

MSK pain reported by 521 of persons aged 18 years and older in 2012

LBP most common (286) NP third most common (152)

(Knee pain second most common at 181)

Females report MSK pain more frequently than males (546 vs

495) The prevalence of LBP and NP highest

for persons age 45 to 64 years

MUSCULOSKELETAL (MSK) DISORDERS ndash US DATA

About half (496)of the total disability burden associated

with MSK disorders is from LBP

NP (201) also caused

substantial disability burden

Between 1998-2011 total direct and indirect costs of

musculoskeletal conditions rose from $3961 billion to $8738

billion ( 121)

Over the same period of time the US Gross Domestic Product

(GDP) has risen from $115 trillion to $152 trillion ( 32)

MUSCULOSKELETAL (MSK) DISORDERS - COST

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 5: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

NECK PAIN (NP)

Pain in the neck withwithout pain referred into one or both upper extremities

In some cases pain may be associated with headaches

LOW BACK PAIN (LBP)

Pain on the posterior aspect of the body

from the lower margin of the 12th rib to the lower gluteal folds withwithout pain referred into one or both extremities

EPIDEMIOLOGY

NECK PAIN - PREVALENCE

Global point prevalence in 2010 - 49 Peaks at a young age - 45 years

Higher in females ndash 58 vs 40

LOW BACK PAIN

Global point prevalence in 2010 ndash 94 Higher in males 101 vs 87 Peaks at approx 80 years of age

Prevalence total number of

cases of a disease in a given

population at a specific time

MSK pain reported by 521 of persons aged 18 years and older in 2012

LBP most common (286) NP third most common (152)

(Knee pain second most common at 181)

Females report MSK pain more frequently than males (546 vs

495) The prevalence of LBP and NP highest

for persons age 45 to 64 years

MUSCULOSKELETAL (MSK) DISORDERS ndash US DATA

About half (496)of the total disability burden associated

with MSK disorders is from LBP

NP (201) also caused

substantial disability burden

Between 1998-2011 total direct and indirect costs of

musculoskeletal conditions rose from $3961 billion to $8738

billion ( 121)

Over the same period of time the US Gross Domestic Product

(GDP) has risen from $115 trillion to $152 trillion ( 32)

MUSCULOSKELETAL (MSK) DISORDERS - COST

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 6: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

EPIDEMIOLOGY

NECK PAIN - PREVALENCE

Global point prevalence in 2010 - 49 Peaks at a young age - 45 years

Higher in females ndash 58 vs 40

LOW BACK PAIN

Global point prevalence in 2010 ndash 94 Higher in males 101 vs 87 Peaks at approx 80 years of age

Prevalence total number of

cases of a disease in a given

population at a specific time

MSK pain reported by 521 of persons aged 18 years and older in 2012

LBP most common (286) NP third most common (152)

(Knee pain second most common at 181)

Females report MSK pain more frequently than males (546 vs

495) The prevalence of LBP and NP highest

for persons age 45 to 64 years

MUSCULOSKELETAL (MSK) DISORDERS ndash US DATA

About half (496)of the total disability burden associated

with MSK disorders is from LBP

NP (201) also caused

substantial disability burden

Between 1998-2011 total direct and indirect costs of

musculoskeletal conditions rose from $3961 billion to $8738

billion ( 121)

Over the same period of time the US Gross Domestic Product

(GDP) has risen from $115 trillion to $152 trillion ( 32)

MUSCULOSKELETAL (MSK) DISORDERS - COST

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 7: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

NECK PAIN - PREVALENCE

Global point prevalence in 2010 - 49 Peaks at a young age - 45 years

Higher in females ndash 58 vs 40

LOW BACK PAIN

Global point prevalence in 2010 ndash 94 Higher in males 101 vs 87 Peaks at approx 80 years of age

Prevalence total number of

cases of a disease in a given

population at a specific time

MSK pain reported by 521 of persons aged 18 years and older in 2012

LBP most common (286) NP third most common (152)

(Knee pain second most common at 181)

Females report MSK pain more frequently than males (546 vs

495) The prevalence of LBP and NP highest

for persons age 45 to 64 years

MUSCULOSKELETAL (MSK) DISORDERS ndash US DATA

About half (496)of the total disability burden associated

with MSK disorders is from LBP

NP (201) also caused

substantial disability burden

Between 1998-2011 total direct and indirect costs of

musculoskeletal conditions rose from $3961 billion to $8738

billion ( 121)

Over the same period of time the US Gross Domestic Product

(GDP) has risen from $115 trillion to $152 trillion ( 32)

MUSCULOSKELETAL (MSK) DISORDERS - COST

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 8: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

MSK pain reported by 521 of persons aged 18 years and older in 2012

LBP most common (286) NP third most common (152)

(Knee pain second most common at 181)

Females report MSK pain more frequently than males (546 vs

495) The prevalence of LBP and NP highest

for persons age 45 to 64 years

MUSCULOSKELETAL (MSK) DISORDERS ndash US DATA

About half (496)of the total disability burden associated

with MSK disorders is from LBP

NP (201) also caused

substantial disability burden

Between 1998-2011 total direct and indirect costs of

musculoskeletal conditions rose from $3961 billion to $8738

billion ( 121)

Over the same period of time the US Gross Domestic Product

(GDP) has risen from $115 trillion to $152 trillion ( 32)

MUSCULOSKELETAL (MSK) DISORDERS - COST

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 9: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

About half (496)of the total disability burden associated

with MSK disorders is from LBP

NP (201) also caused

substantial disability burden

Between 1998-2011 total direct and indirect costs of

musculoskeletal conditions rose from $3961 billion to $8738

billion ( 121)

Over the same period of time the US Gross Domestic Product

(GDP) has risen from $115 trillion to $152 trillion ( 32)

MUSCULOSKELETAL (MSK) DISORDERS - COST

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 10: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Between 1998-2011 total direct and indirect costs of

musculoskeletal conditions rose from $3961 billion to $8738

billion ( 121)

Over the same period of time the US Gross Domestic Product

(GDP) has risen from $115 trillion to $152 trillion ( 32)

MUSCULOSKELETAL (MSK) DISORDERS - COST

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 11: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

RISK FACTORS

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 12: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Gender Regardless of age MK pain more common among working women than working men

(Herin F et al Pain 2014 155 937-43)

Women seem to have sensitivity to pain (Leville SG et al Pain 2005 116 332-8)

Age Highest incidence of NP and LBP in the 3rd-

4th decade and overall prevalence increasing until age 60-65

(Hoy D et al Best Pract Res Clin Rheumatol 2010 24 769-81)

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 13: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Occupational factors

Repetitive work awkward postures vibrations

(Neupane S et al Int Arch Occup Environ Health 2013 86 581-9)

(Herin F et al Pain 2014 155 937-43)

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 14: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Psychosocial Factors

High level of emotional distress anxiety depression fear of

movement with avoidance behaviors (resting and limping)

correlated with high level of NPsup1 and LBPsup2 disability

(Johansen JB et al Clin J Pain 2013 29 1029-1035sup1)

(Grotle M et al Pain 2004 112 343-352sup2)

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 15: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Job dissatisfaction work requiring repetitive tasks

limited autonomy and opportunities for learning and growing

professionally (van Tulder M et al Clin Rheum 2002 16(5) 761-75

risk of MSK pain in women

(Herin F et al Pain 2014 155 937-43)

Lower levels of education - strong predictor of more prolonged episode duration and poorer

outcome (Chou R et al Ann Int Med 2007 147(7) 478-91)

(Deyo RA et al Spine 2006 31 2724-7)

Psychosocial Factors

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 16: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Problems with sleep

Sometimes - Risk of developing chronic NP LBP - 22-32

OftenAlways - 51-66 (PJ Moork et al Eur J of Pub Health 2013

24(6) 924-29)

Lack of sleep induces a state of low-level systemic inflammation that sensitizes the

nociceptive system (Haack M et al Sleep 2007 30 1145-52) (Wang H et al Clin J Pain 2008 24 273-8)

FROM THE MOVIE ldquoInsomniardquo

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 17: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Lack of exercise - Increased body weight

Lack of sleep ndash Lack of physical exercise ndash Increased body weight ndash bad combination

(PJ Moork et al Eur J of Pub Health 2013 24(6) 924-29)

Lack of physical activityIncreased BMI

low-grade systemic inflammation that the susceptibility to chronic pain (Roytblat L et al Obesity 2000 8 673-5)

(Petersen AMW et al J Appl Physiol 2005 98 1154-62)

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 18: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

SOURCES OF NECK AND LOW BACK PAIN

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 19: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

a Large disk herniation at the C5-6 disk level

b Right sided disk herniation with nerve root compromise

Patient likely to complain of NP radiated to right upper extremity shooting stabbing

electrical shock-like with paresthesiae

CERVICAL-LUMBAR INTERVERTEBRAL DISK

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 20: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

MECHANISM Inflammation of the nerve roots

When a disk ruptures inflammatory

mediators are released from the nucleus polposus (the inner part of the disk)

around the nerve root leading to chemical neuroradiculitis

CERVICAL-LUMBAR INTERVERTEBRAL DISK

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 21: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

True synovial joints

between the C2-C7 vertebrae located behind the plane of the intervertebral foramina

and the spinal nerves contained therein

Arthritic changes may cause axial neck pain withwithout upper extremity pain

CERVICAL FACET JOINTS

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 22: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

CERVICAL FACET JOINTS

C2-3 C5-6 C6-7

most frequent

facetogenic pain

generators in the cervical

spine

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 23: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

CERVICAL FACET JOINTS

C2-3 joint Pain in the sub-occipital region

radiating to occiput auricular region vertex of the head forehead and orbit

C5-6 joint

Pain radiates over the deltoid region and into the arm

C6-7 joint Pain radiates over

over the medial scapula

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 24: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

ATLANTO-AXIAL JOINT (C1-2)

Pain from C1-2 occurs higher than pain from C2-3

vertex rather than forehead and temple

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 25: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

ATLANTO-OCCIPITAL JOINT (C 0-1)

Pain from C 0-1 almost superimposes pain stemming

from C1-2

Unusual source of neck pain

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 26: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Note the close anatomic relationship between C0-

1 joint and C1 nerve

between C1-2 joint and C2 ganglia and nerve

and between these joints and the vertebral artery

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 27: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

OTHER SOURCES OF NECK PAIN

Posterior neck muscles

Cervical dura mater

Atlanto-axial joint ligaments

Vertebral artery

Cervical vertebral bodies

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 28: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

True synovial joints with a space a synovial membrane hyaline cartilage surfaces and a

fibrous capsule located in front of the plane of the foramina and the nerve root therein

Arthritic changes may cause axial low back pain withwithout lower extremity pain

LUMBAR FACET JOINTS

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 29: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

LUMBAR FACET JOINTS PAIN CHARACTERISTICS

More common in patients 65

yearolder

Axial low back pain

withwithout radiation to the

lower extremities

Morning stiffness Pain when

starting to move relieved by

the recumbent position

Worsening as day goes by

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 30: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

LUMBAR FACET JOINTS PAIN PATTERNS

L4-5 L5-S1

most frequent facetogenic

pain generators in the lumbar

spine

Pain does not extend down

beyond the level of the knee

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 31: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Largest axial joint in the

body

Only the anterior third is a

true synovial joint

Complex innervation

including sensory fibers

from L5 through S4 spinal

nerves

SACRO-ILIAC JOINT

A B

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 32: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

No difference in gender

Mean age 40-50

Prevalence 13-30 of

patients with ho low back

pain

Most commonly causing

unilateral symptoms

SACRO-ILIAC JOINT

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 33: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Pain is always maximal below L5

May radiate to hips groin buttocks

posterior thighs

Patterns of referred pain somewhat

similar to those due to disk and orfacet

joint mediated pain

SACRO-ILIAC JOINT PAIN PATTERN

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 34: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

PIRIFORMIS MUSCLE

Located in the gluteal region is one of the muscles of the lateral

rotator group

It is situated within the posterior wall of the pelvis partly at the

back of the hip joint

Passes out of the pelvis through the greater sciatic foramen

Sciatic nerve

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 35: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

PIRIFORMIS MUSCLE

Sport activities andor certain movements (running lunging) can

stress the piriformis muscle

The subsequent muscle spasm may manifest as MSK low back pain

radiating to the buttock and along the sciatic nerve

Prolonged sitting stretching climbing stairs or walking on inclines squatting

worsen the pain

REALLY A PAIN THE BUTT

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 36: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

OTHER SOURCES OF LOW BACK PAIN

Posterior lumbo-sacral paraspinal pelvic girdle muscles

Lumbar spine ligaments tendons

Vertebral bodies

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 37: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

CAUSES OF NECK AND LOW BACK PAIN

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 38: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

TUMORS

INFECTIONS Discitis Osteomyelitis Septic arthritis Meningitis

VASCULAR DISORDERS (egCarotid artery dissection)

AUTOIMMUNE DISORDERS Rheumatoid arthritis Ankylosing spondylitis Polymyalgia rheumatica

TRAUMA (FracturesDislocations)

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 39: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

MSK DISORDERS Soft tissue injuries Whiplash CervicalLumbosacral

strain Myofascial disorders Fibromyalgia

JOINT DISORDERS Spondylosis and Osteoarthritis

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 40: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

MANAGEMENT

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 41: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Self limited condition

Symptoms and disability improve rapidly

Most patients return to work and normal activities in 4-6 weeks

(Pengel LH et al BMJ 2003 327 323)

NATURAL HISTORY

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 42: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

1 in 3 patients

Persistent moderate pain 1 year after an acute episode

1 in 5 patients report substantial limitations in activity (von Korff al et al Spine 1996 21 2833-7 ndash discussion 2838-9)

NATURAL HISTORY

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 43: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

History and Physical Exam

Blood work to rule out the

presence of a malignancy andor an infection

Plain radiographs of

cervicallumbar spine CTMRI in patients with neurologic

complaints or with pain not improving

DIAGNOSIS

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 44: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

MAIN GOAL

Achieve adequate pain control (NSAIDs Tylenol Muscle

Relaxants Gabapentinoids short acting opioids)

Relative rest

Activity modifications

INITIAL MANAGEMENT

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 45: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Epidural steroid injections are an

option in patients with disk herniation back and leg pain

INITIAL MANAGEMENT

Anesth Analg 2016 Mar122(3)857-70 Bhatia A1 Flamer D Shah PS Cohen SP

CONCLUSIONS Epidural steroids injections provide

some analgesic benefit at 3 months in patients with lumbosacral radicular pain

due to herniated intervertebral disks but they have no impact on physical

disability or incidence of surgery

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 46: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Epidural steroid injections are an option in

patients with spinal stenosis

INITIAL MANAGEMENT

Spinal stenosis causes mechanical compression of the nerve roots swelling

(microvascular injury) producing pain (Olmarker K et al Spine 1989 14 569-573)

L3-4 Spinal Stenosis

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 47: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

INITIAL MANAGEMENT

STEROIDS

inhibit swelling (edema) around the nerve root

(Rydevik B et al Spine 1984 9 7-15)

improve blood flow to neural elements decreasing ischemic neuritis

(Fukusaki M et al Clin J Pain 1998 14 148-51)

block conduction in nociceptive nerve fibers (Johansson A et al Acta Anesthesiol Scand

1990 34 335-38) L4-5 Severe Spinal Stenosis

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 48: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

INITIAL MANAGEMENT

Usually spinal stenosis occurs in pts of senior age

Some of these patients may significant comorbidities and higher sensitivity to

pain medications

Multilevel Cervical Spinal Stenosis

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 49: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

INITIAL MANAGEMENT

Intra-articular facet joint injections are appropriate when a clinical

diagnosis of facet joint ldquosyndromerdquo is confirmed

Axial back pain withwithout radiation

to the extremities

Morning neckback stiffness Pain when starting to move worse on necklumbar

spine extension relieved by the recumbent position

Intra-articular C3-4 facet joint injection

Intra-articular L5-S1 facet joint injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 50: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP secondary

to SI Joint ldquoSyndromerdquo

Pain is always maximal below L5

May radiate to hips groin buttocks posterior thighs

Patterns of referred pain somewhat similar to those due to disk and orfacet joint mediated

pain

Intra-articular SI Joint Injection

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 51: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

INITIAL MANAGEMENT

Injections helpful in diagnosis and management of LBP due to Piriformis Muscle Syndrome

A REAL PAIN THE BUTT

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 52: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

INITIAL MANAGEMENT ACUPUNCTURE

Some evidence that acupuncture and variations

thereof (acupressure cupping) potentially helpful in the acutesubacute period in

patients with NP and LBP

(Yuan QI et al PloS One 2015 Febr 1-37)

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 53: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

NEXT STEP

Rehabilitation and regaining of function

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 54: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

Physical Therapy very important component of the

rehabilitation

A symbiotic relationship between patient and

therapist key of a successful physical rehabilitation

program

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 55: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

The role of YOGA

Better pain control at rest and with

activities with yoga (9-week program with weekly 90-minute classes) when

compared to a self care exercise program in patients with neck pain

Significant treatment effects of yoga found for pain-related apprehension

disability quality of life and psychological outcomes (depression

fatigue anger)

(Michalsen A et al the J Pain 2012 13(11) 1122-30)

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 56: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

THE IMPORTANCE OF REMAINING ACTIVE

Increasing the amount of steps

walkedday by 1000 over the course of a year reduced the risk of neck pain by

14 in a group of people (men and women age 20-45) with sedentary jobs

(Sitthipornvorakul EA et al Eur Spine J

2015 24 417-24)

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 57: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

SPINAL MANIPULATION No Thank you

Systematic review of spinal

manipulation in patients with a variety of pain conditions including NP

and LBP

Failed to demonstrate that spinal manipulation is an effective

intervention for pain management

(Posadzki P Pain Med 2012 13 754-61)

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 58: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

CONCLUSIONS

Neck and Low Back pain syndromes are usually self limited conditions that can convert in chronic pain conditions causing

prolonged disability

The prevalence and cost of these conditions has significantly increased over the course of the last 15-20 years

Aggressive management of pain during the acute phase is

important because adequate pain control shortens the time and level of disability and facilitates the rehabilitation process

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 59: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

CONCLUSIONS

A variety of treatment modalities including medications acupuncture injections PT Yoga are utilized to manage pain and facilitate the

recovery process

Reducing stress and activities associated with the generation of pain maintaining an appropriate physical exercise regimen and a body weight

as close as possible to the ideal body weight will likely result in a decreased incidenceprevalence of short and long term NP and LBP

THANK YOU

QUESTIONS

Page 60: MINI-MEDICAL SCHOOL My Aching Neck My Aching Backucsfcme.com/minimedicalschool/syllabus/winter2016/DePinto.pdfBetween 1998-2011, total direct and indirect costs of musculoskeletal

THANK YOU

QUESTIONS