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Ministero della SaluteDirezione Generale Ricerca Sanitaria e Biomedica e della Vigilanza sugli Enti

CODICE PROGETTO DESTINATARIO ISTITUZIONALE

Tipologia Classificazione 1 Liv.

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BANDO 2011‐2012 RICERCA FINALIZZATA ‐GRADUATORIA PROGETTI ORDINARIAREA

STRATEGICA

RF‐2011‐02348435

Investigation of the role of extracellular ATP and the P2X7 receptor in the modulation of immunosuppression within tumour microenvironment

Emilia‐Romagna Biomedical Immunology 5Oncology

RF‐2011‐02351840

Defective Glucose Metabolism in Polycystic Kidney Disease Defines a Novel Therapeutic Strategy: a Pre‐Clinical Proof‐of‐Concept Study

SAN RAFFAELE Milano Biomedical Digestive, Kidney and Urological Systems

5Metabolism disorders and cardiovascular disease

RF‐2011‐02352006

Gender and geographical specific circulating microRNA signatures as biomarkers of atherosclerosis, atherosclerosis progression and vascular events

MONZINO Clinical Vascular and Hematology 5,5Metabolism disorders and cardiovascular disease

RF‐2011‐02348315

Defining the cis‐regulatory bases for variability in inflammatory gene expression in humans: a 3‐D analysis in the nuclear space

I.E.O. Biomedical Genes, Genomes and Genetics 5,5Infection and immunity

RF‐2011‐02350693

To unravel the molecular basis of neurodevelopmental disorders

CASA SOLLIEVO SOFFERENZA

Biomedical Genes, Genomes and Genetics 5,5Neurological diseases

Pagina 1 di 231



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STRATEGICA

RF‐2011‐02351092

"Detection of pathological prion protein in cerebrospinal fluid by real‐time quaking induced conversion (QuIC): Evaluation and standardization of a novel disease‐specific laboratory test for the diagnosis of sporadic Creutzfeldt‐Jakob disease."

Ist.Sci. Neurologiche Bologna

Biomedical Brain Disorders and Clinical Neuroscience

6Neurological diseases

RF‐2011‐02348358

Immune, procoagulant and inflammatory responses in severe sepsis and septic shock

MAGGIORE Biomedical Immunology 6Infection and immunity

RF‐2011‐02347228

Altered host‐virus interaction as cause of multiple sclerosis: focus on Epstein‐Barr virus and antiviral immune response

ISS Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02352291

Assessment of the macrophage role in the natural history of myeloproliferative neoplasms

SAN RAFFAELE Milano Biomedical Oncology 1 ‐ Basic Translational 6,5Oncology

RF‐2011‐02352852

Dynamics and ultrastructure of stress sensing

SAN RAFFAELE Milano Biomedical Cell Biology 6,5The new biotechnologies

RF‐2011‐02350836

New nano‐systems for targeted delivery of cytokines to tumors

SAN RAFFAELE Milano Biomedical Oncology 2 ‐ Translational Clinical 6,5Oncology

RF‐2011‐02350857

Role of anoctamin‐1 in iodide transport and implications for the efficacy of radioiodine‐based cancer therapy.

Emilia‐Romagna Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences

6,5Oncology

RF‐2011‐02346976

Identification of critical p53 co‐regulators and effectors during tumor suppression

I.E.O. Biomedical Genes, Genomes and Genetics 6,5Oncology

Pagina 2 di 231



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STRATEGICA

RF‐2011‐02350617

Determinants of Type 1 Diabetes (T1DM) clinical onset and progression in paediatric immigrant population

Piemonte Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences

6,5Metabolism disorders and cardiovascular disease

RF‐2011‐02348466

GENome‐wide association study to Evaluate genetic risk factors for cerebral sinus‐venous thromboSIS (GENESIS Study)

MAGGIORE Biomedical Genes, Genomes and Genetics 6,75Metabolism disorders and cardiovascular disease

RF‐2011‐02349806

Mitochondrial targeting in LRRK2‐associated parkinsonism (PARK8)

SANTA LUCIA Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02350347

An integrated genomic, transcriptomic and epigenomic approach in multiplex multiple sclerosis families.

SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 7Neurological diseases

RF‐2011‐02349985

Production of novel diagnostic and therapeutic antibodies directed against stem cells in colorectal and lung cancer

REGINA ELENA Biomedical Oncology 2 ‐ Translational Clinical 7Oncology

RF‐2011‐02351165

Translational genetics of hereditary spinocerebellar degenerations: high‐throughput exome sequencing and model organisms for the identification and characterization of novel disease genes

CARLO BESTA Biomedical Genes, Genomes and Genetics 7Neurological diseases

RF‐2011‐02351474

Dysregulated RNA metabolism in multiple myeloma

SAN RAFFAELE Milano Biomedical Oncology 1 ‐ Basic Translational 7Oncology

RF‐2011‐02352582

N‐acetylcysteine in the treatment of neuropathic pain

NEUROMED Biomedical Brain Disorders and Clinical Neuroscience


Pagina 3 di 231



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STRATEGICA

RF‐2011‐02352331

Systemic Sclerosis and Chronic Graft versus Host Disease: application of novel predictive assays and generation of transgenic animal models

Marche Biomedical Immunology 7Infection and immunity

RF‐2011‐02347869

CHANGES IN STRUCTURE AND RECRUITMENT OF MUSCLE SYNERGIES AFTER CORTICAL AND CEREBELLAR

LESIONS

SANTA LUCIA Biomedical Integrative, Functional, and Cognitive Neuroscience

7,25Neurological diseases

RF‐2011‐02347691

Generation and functional characterization of artificial lymphoid organs with mutipotent stromal progenitors

SAN RAFFAELE Milano Biomedical Biology of Development and Aging 7,25Oncology

RF‐2011‐02350689

Role of regulatory cells and cytokines in the extent of colonic involvement in patients with ulcerative colitis: implications for

patient‐oriented therapy

ISS Biomedical Digestive, Kidney and Urological Systems

7,5Infection and immunity

RF‐2011‐02346987

Development of a second generation PCR‐Based Replicon Typing system to trace and control the antimicrobial resistance spread in Enterobacteriaceae

ISS Biomedical Infectious Diseases and Microbiology


RF‐2011‐02347907

Enhanced cell therapy: novel strategies to improve transplanted cell survival and engraftment by protection from oxidative

stress

REGINA ELENA Biomedical Vascular and Hematology 7,5Metabolism disorders and cardiovascular disease

RF‐2011‐02347253

Identification and validation of new therapeutic targets in Acute Myeloid Leukaemia

I.E.O. Biomedical Oncology 1 ‐ Basic Translational 7,5Oncology

Pagina 4 di 231



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STRATEGICA

RF‐2011‐02348444

Inherited arrhythmias: clinical characterization, genetic geography and experimental studies in the Calabria Region isolate.

MAUGERI Biomedical Genes, Genomes and Genetics 7,5Metabolism disorders and cardiovascular disease

RF‐2011‐02347470

Regulation of mitotic transitions I.E.O. Biomedical Cell Biology 7,5Oncology

RF‐2011‐02352638

ADIPOSE‐DERIVED MESENCHYMAL STEM CELLS AS NEW MINIMALLY INVASIVE REGENERATIVE TREATMENT TO TARGET EARLY OSTEOARTHRITIS: FROM PRE‐CLINICAL PROCEDURE SELECTION TO CLINICAL APPLICATION IN A RANDOMIZED DOUBLE‐BLINDED CONTROLLED TRIAL

RIZZOLI Clinical Musculoskeletal, Oral and Skin Sciences

7,5The new biotechnologies

RF‐2011‐02350228

Steroid myopathy: pathogenesis and prevention

MAUGERI Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02346867

The role of mechanobiology in establishment and progression of intima hyperplasia associated to vein coronary bypass grafts disease

MONZINO Biomedical Vascular and Hematology 7,5Metabolism disorders and cardiovascular disease

RF‐2011‐02350023

Evaluation of the potential application of bivalve shellfish as bioindicators of pollution for viral pathogens in coastal waters of southern Italy

IZS Mezzogiorno Biomedical Veterinary 7,5Food safety and animal welfare

RF‐2011‐02350097

Skeletal muscle in Spinal and Bulbar Muscular Atrophy (SBMA): therapeutic target and delivery route for potential treatments

Veneto Biomedical Brain Disorders and Clinical Neuroscience


Pagina 5 di 231



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STRATEGICA

RF‐2011‐02351229

Stress‐Activated Protein Kinases MLK3 and p38 as novel therapeutic targets in chemokine‐driven leukocyte extravasation and non‐resolving inflammatory processes

SAN RAFFAELE Milano Biomedical Immunology 7,5Infection and immunity

RF‐2011‐02348796

ETHYL‐EICOSAPENTAENOIC ACID ADDED TO INTERFERON ß THERAPY IN RELAPSING‐REMITTING MULTIPLE SCLEROSIS: A RANDOMIZED PHASE II

CLINICAL TRIAL.



RF‐2011‐02347946

An image‐analysis platform for automated in‐situ high‐content and resolution analysis of tumor heterogeneity: targeting genomic, epigenetic, and functional diversity in tissues by fluorescence microscopy

I.E.O. Biomedical Bioengineering Sciences and Technologies

7,75Oncology

RF‐2011‐02347197

Epidrugs and cardiac differentiation: relevance for the 22q11.2 deletion syndrome

NEUROMED Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02349938

From Bench to Bedside: an Integrated Approach to RASopathies

ISS Biomedical Genes, Genomes and Genetics 8Metabolism disorders and cardiovascular disease

RF‐2011‐02347596

LEKTI, a multifunctional protein involved in skin desquamation and immunity: towards novel therapeutic approaches for rare and common skin diseases

IDI Biomedical Musculoskeletal, Oral and Skin Sciences

8Infection and immunity

RF‐2011‐02351998

New Molecular Mechanisms of Leukemia Immune Evasion after Allogeneic Hematopoietic Stem Cell Transplantation

SAN RAFFAELE Milano Biomedical Oncology 2 ‐ Translational Clinical 8Oncology

Pagina 6 di 231



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STRATEGICA

RF‐2011‐02347120

Cell‐on‐chip technology as a novel tool to investigate the crosstalk between cancer and immune cells: role of the transcription factors Interferon Regulatory Factor 1 and 8 (IRF1, IRF8) in melanoma as a model system.

ISS Biomedical Oncology 1 ‐ Basic Translational 8The new biotechnologies

RF‐2011‐02350485

NEUROSTEROIDS AS DETERMINANTS OF ANTIEPILEPTIC DRUG REFRACTORINESS IN TEMPORAL LOBE EPILEPSY

Emilia‐Romagna Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02350464

New self‐powered devices for cochlear stimulation based on piezoelectric nanomaterials

Toscana Biomedical Bioengineering Sciences and Technologies

8The new biotechnologies

RF‐2011‐02347337

Dendritic cell‐based vaccine therapy in indolent non‐Hodgkin lymphoma patients: a phase I clinical study

ISS Biomedical Oncology 2 ‐ Translational Clinical 8Oncology

RF‐2011‐02350993

Investigation of a novel engineered probiotic to treat Clostridium difficile infection

SAN RAFFAELE Milano Biomedical Infectious Diseases and Microbiology


RF‐2011‐02349126

Hypoxia, Inflammation and redox status as determinants of malignant progression of cancer stem cells

SAN RAFFAELE Pisana‐Roma

Biomedical Oncology 1 ‐ Basic Translational 8Oncology

RF‐2011‐02348970

Structure and biology of the Tat/Env complex and role of anti‐Tat/Env antibodies in HIV infection: implication for HIV/AIDS preventative vaccine development

ISS Biomedical AIDS and Related Research 8Infection and immunity

Pagina 7 di 231



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STRATEGICA

RF‐2011‐02348476

ROLE OF THE NOVEL PRESYNAPTIC PROTEIN PRRT2 IN NEURONAL PHYSIOLOGY AND IN THE PATHOGENESIS OF PAROXYSMAL NEUROLOGICAL DISORDERS

SAN RAFFAELE Milano Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02351876

Vitamin D deficiency and obesity after kidney transplantation: multicenter study on gene‐environment interactions leading to "complex‐phenotypes" in a human system associated with cardiovascular events and graft rejection.

Piemonte Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02348684

Taking a step forwards the preparedness for preventing crises: Improving the molecular detection of emerging pathogens in food.

IZS Piemonte, Liguria e Valle d'Aosta

Biomedical Veterinary 8,5Food safety and animal welfare

RF‐2011‐02346754

Tie2 monocyte‐mediated delivery of IFN‐alpha into the liver as a novel treatment for colorectal carcinoma (CRC) liver metastases.


RF‐2011‐02352379

Sensorimotor Integration. Physiology and Pathophysiology

MAUGERI Biomedical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02349712

Genomic complexity of chronic lymphocytic leukemia (CLL): clinicobiologc implications and pharmacoeconomic evaluation at the beginning of the kinase‐targeted treatment era

Emilia‐Romagna Clinical Oncology 2 ‐ Translational Clinical 8,5Oncology

RF‐2011‐02352318

Immunological Mechanisms Involved in The Pathogenesis of Primary Aldosteronism

Veneto Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


Pagina 8 di 231



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STRATEGICA

RF‐2011‐02352308

¿WHY ME?¿ PROJECT (WM?P). INVESTIGATING WHITE MATTER CONNECTIVITY IN SCHIZOPHRENIA AT IMAGING, CELLULAR, AND TRANSPOSONE LEVELS IN MONOZYGOTIC DISCORDANT TWINS

MEDEA Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349693

Vibrio and viruses in shellfish: old and emerging pathogens. Evaluation of exposure levels for the implementation

ofprevention strategies.

ISS Biomedical Veterinary 8,5Food safety and animal welfare

RF‐2011‐02349921

THE ROLE OF THE BRAIN‐ADIPOCYTE AXIS ACTIVITY IN POTENTIATING ANTIDEPRESSANT EFFICACY

ISS Biomedical Biobehavioral and Behavioral Processes


RF‐2011‐02346771

Does gut flora influence autoimmune responses in Multiple Sclerosis? The MAIT cell story.

SANTA LUCIA Biomedical Immunology 8,5Infection and immunity

RF‐2011‐02347224

CCL2/CCR2 blocking:molecular insights into a potential therapeutic strategy against HIV replication

ISS Biomedical AIDS and Related Research 8,5Infection and immunity

RF‐2011‐02347300

Specialized‐functionally connected membranes as caveolae and exosomes include molecular signature to decode melanoma progression mechanisms exploitable in clinical therapy

ISS Biomedical Cell Biology 8,5Oncology

RF‐2011‐02350455

Electromagnetic guided in‐situ laser fenestration of endovascular endoprosthesis

Toscana Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


Pagina 9 di 231



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STRATEGICA

RF‐2011‐02349269

From protein‐protein interaction studies new potential therapeutic targets to treat the MLL‐related acute lymphoblastic leukemias

SDN Biomedical Oncology 1 ‐ Basic Translational 8,5Oncology

RF‐2011‐02348164

CARDIOriGEN ‐ MicroRNAs inducing cardiac regeneration ‐ From discovery towards clinical application

Friuli‐Venezia Giulia Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02351158

Beta‐adrenoceptor antagonism and biased agonism in the control of pathological neovascularization

ISS Biomedical Biological Chemistry and Macromolecular Biophysics


RF‐2011‐02352088

Meeting senior members in the search for new associatesof the exclusive

hamartromatous gene club

Puglia Biomedical Digestive, Kidney and Urological Systems

8,5Oncology

RF‐2011‐02348346

A long ncRNA point‐of‐view to FSHD muscular dystrophy pathophysiology and therapeutics.

SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 8,5Neurological diseases

RF‐2011‐02349671

Exploring the role of the prokineticin system in experimental autoimmune encephalomyelitis: a preclinical study towards the definition of possible novel targets of therapy for human multiple sclerosis

CARLO BESTA Biomedical Immunology 9Neurological diseases

RF‐2011‐02347362

Induced pluripotent stem cells (iPSCs) as a tool to develop neuroprotective (autologous) neural stem cell‐based therapy in multiple sclerosis

SAN RAFFAELE Milano Biomedical Brain Disorders and Clinical Neuroscience


Pagina 10 di 231



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STRATEGICA

RF‐2011‐02349717

A new therapeutic window in neurorehabilitation

FATEBENEFRATELLI Biomedical Biobehavioral and Behavioral Processes


RF‐2011‐02349251

INFLAMMATORY AND THROMBOCCLUSIVE VASCULOPATHY: THE ROLE OF PROTEINS RELATED TO

COMPLEMENT ACTIVATION.

C.R.O. AVIANO Biomedical Vascular and Hematology 9Metabolism disorders and cardiovascular disease

RF‐2011‐02347490

Uncovering the molecular bases of the association of uromodulin common variants with hypertension and chronic kidney disease for the identification of novel therapeutic strategies

SAN RAFFAELE Milano Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02348839

Identification of therapeutic targets for neurological disorders: analysis of the mechanisms regulating cortical

interneuronsdevelopment.



RF‐2011‐02349698

Individual risk in clinically isolated syndromes of conversion to multiple sclerosis and disease progression: an integrated public health clinical genomics approach

SAN RAFFAELE Milano Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02347608

Clostridium difficile infection in Italy: do we know the true magnitude of the problem?

SPALLANZANI Clinical Infectious Diseases and Microbiology


RF‐2011‐02350972

MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF MECHANISMS INVOLVED IN IRON HOMESTASIS AND HEME SYNTHESIS IN ß THALASSEMIC ERYTHROPOIESIS

MAGGIORE Biomedical Genes, Genomes and Genetics 9Metabolism disorders and cardiovascular disease

Pagina 11 di 231



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STRATEGICA

RF‐2011‐02347675

Radiation biodosimetry in emergency: validation of automated scoring and accuracy of dose prediction

AOU San Martino‐IST ‐Genova

Biomedical Oncology 1 ‐ Basic Translational 9Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02352111

Expression and function of P2 receptors in human psoriatic keratinocytes. Study of their role in psoriasis pathogenesis and research of new potential therapeutic targets

Emilia‐Romagna Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02350556

Low‐cost cardio‐pulmonary monitoring system for avoidable death prevention in the hospital general ward

Piemonte Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02350971

The role of early systematic best palliative care versus on request palliative care consultation during standard oncologic treatment for patients with advanced gastric or pancreatic cancers: a randomized, controlled, multicenter trial

IRST Meldola Clinical Healthcare Delivery and Methodologies

9Oncology

RF‐2011‐02352131

GLP‐1 agonists treatment vs endoscopic procedures in obesity and type II diabetes mellitus management: a randomized clinical trial.



RF‐2011‐02347971

Molecular regulation of the redox switch in inflamed skeletal muscle as a novel target to implement muscle regeneration and limit fibrosis in immune‐mediated myositis

SAN RAFFAELE Milano Biomedical Musculoskeletal, Oral and Skin Sciences


Pagina 12 di 231



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STRATEGICA

RF‐2011‐02348151

Identification and manipulation of immunosuppressive networks in tumor microenvironment of patients undergoing immunobiological therapies.

SAN RAFFAELE Milano Biomedical Immunology 9Oncology

RF‐2011‐02351216

Cortico‐cortical functional connectivity and recovery of post‐stroke spatial attention and awareness disorders



RF‐2011‐02349556

Impact of asbestos‐mediated inflammation in mesothelioma genesis and progression. Implication for early diagnosis, prognosis and therapy

HUMANITAS Biomedical Oncology 1 ‐ Basic Translational 9Oncology

RF‐2011‐02351149

Dominant optic atrophy (DOA) and OPA‐thies in Italy (ITA‐DOA): minimal prevalence, genetics and phenotypes, and cell models of disease towards a therapy.




RF‐2011‐02351889

Eco‐epidemiology of Mycobacterium bovis infection in Mediterranean area: a multi‐disciplinary approach.

IZS Sicilia Biomedical Veterinary 9Infection and immunity

RF‐2011‐02347935

PRECLINICAL DEVELOPMENT OF THERAPEUTIC, ANTI‐BETA‐GLUCAN ANTIBODIES FOR UNIVERSAL PROTECTION AGAINST FUNGAL PATHOGENS



RF‐2011‐02347945

Caffeine as a potential therapeutic option for Alzheimer's disease



Pagina 13 di 231

vincenzo

Sottolineato



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STRATEGICA

RF‐2011‐02349393

Human Ewing Sarcoma Family Tumor (ESFT) Revisited From Cancer Stem Cells (CSCs) to the Epigenetic Regulation: cross‐talk between ncRNA and DNA methylation

Lombardia Biomedical Oncology 1 ‐ Basic Translational 9Oncology

RF‐2011‐02350769

Potential role of HDL Cholesterol Efflux Capacity in the evaluation of cardiovascular risk in patients with Familial Hypercholesterolemia (FH)


Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02346892

The low density lipoprotein‐associated protein prenylcysteine lyase: a novel player in atherosclerosis?

MONZINO Biomedical Vascular and Hematology 9Metabolism disorders and cardiovascular disease

RF‐2011‐02348166

Constitutive Axl signaling in human melanoma: role in tumor biology and in resistance to BRAFV600E inhibitors

IST.TUMORI MILANO Biomedical Oncology 1 ‐ Basic Translational 9Oncology

RF‐2011‐02350853

Identification and validation of novel stem cell markers for the stratification of breast cancer patients.

I.E.O. Biomedical Oncology 2 ‐ Translational Clinical 9Oncology

RF‐2011‐02347245

Development of an immunotherapeutic strategy for an effective therapeutic HPV vaccine


RF‐2011‐02346811

Towards a functional classification of human melanoma: dissecting the altered intracellular signaling profile by phosphoproteomics approaches


Pagina 14 di 231



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STRATEGICA

RF‐2011‐02351358

Dietary advanced glycation end products and cardiovascular risk: animal and human studies

ISS Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02348236

CARPEDIEM ‐ Comorbidity And Risk Profiles Evaluation in Diabetes and hEart

Morbidities

Toscana Clinical Healthcare Delivery and Methodologies


RF‐2011‐02347084

Inflammation and oxidative stress in preeclampsia: role of the maternal endothelium and of the placenta, potential role in early markers development

Lombardia Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02349663

Analysis of the possible pathogenic roles of the inflammosome and the microbiota in Alzheimer's disease

DON GNOCCHI Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349068

Development of in vitro insulin‐producing biohybrid organ for the cure of type 1 diabetes

Umbria Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02349321

Involvement of ADAR1‐ and ADAR2‐RNA‐editing activity on myeloid leukemia and myeloid cell differentiation: novel future therapeutic implications.

OSPEDALE BAMBINO GESU'

Biomedical Oncology 1 ‐ Basic Translational 9,5Oncology

RF‐2011‐02349920

Dissecting the role played by mechanotransduction on Cardiac Stem Cell and cardiomyocyte dysfunction.

Friuli‐Venezia Giulia Biomedical Cardiovascular and Respiratory Sciences


Pagina 15 di 231



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STRATEGICA

RF‐2011‐02348098

Phenotypic, functional and genomic characterization of bone fragility in children and adolescents and their relatives: exploring the susceptibility to fractures in youth for its prevention in adulthood

SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 9,5Metabolism disorders and cardiovascular disease

RF‐2011‐02349653

Circulating endothelial progenitor cells as potential predictive and prognostic markers in metastatic colorectal cancer patients

Toscana Biomedical Oncology 2 ‐ Translational Clinical 9,5Oncology

RF‐2011‐02348212

Developmental and genetic bases of Opitz G/BBB Syndrome towards better diagnosis and management of syndromic forms of intellectual disability

BURLO GAROFALO Clinical Genes, Genomes and Genetics 9,5Neurological diseases

RF‐2011‐02348034

A Nationwide Clinical Study on the Role of Functional HLA‐DPB1 Matching in Unrelated Hematopoietic Stem Cell Transplantation

SAN RAFFAELE Milano Clinical Oncology 2 ‐ Translational Clinical 9,5Oncology

RF‐2011‐02350832

Immune therapy with T regulatory type 1 (Tr1) cells in patients with type 1 diabetes undergoing islet transplantation


RF‐2011‐02347806

The epigenetic basis of glioblastoma multiforme invasiveness and recurrence


RF‐2011‐02347187

Structural genomics/proteomics and solution characterization of proteins of biomedical interest: development of a comprehensive facility, application to therapeutic monoclonal antibodies, and to the fibrin(ogen)‐integrins cell‐matrix interactions model sy


Biomedical Biological Chemistry and Macromolecular Biophysics

9,5Oncology

Pagina 16 di 231



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STRATEGICA

RF‐2011‐02347757

Risk assessment of occupational and environmental exposure to benzene and other chemicals at low doses: from molecular mechanisms to biological monitoring

Campania Biomedical Risk, Prevention and Health Behavior

9,5Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02351867

Ghrelin as a new cardiometabolic risk biomarker: from population studies to tissue and cell biology in skeletal muscle and heart.

Friuli‐Venezia Giulia Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02350276

Novel multi‐analyte point‐of‐care testing device for rapid diagnosis and management of sepsis and severe infection.

Toscana Biomedical Interdisciplinary Molecular Sciences and Training


RF‐2011‐02352512

MicroRNA Signatures: Novel Biomarkers for early detection of Colorectal Cancer


Biomedical Oncology 2 ‐ Translational Clinical 9,5Oncology

RF‐2011‐02346966

Epigenetic signatures in human glioblastoma cells: implications for tumor biology and treatment



RF‐2011‐02348457

Regulatory mechanisms and therapeutic targeting of melanoma‐initiating cells

Toscana Biomedical Oncology 1 ‐ Basic Translational 9,5Oncology

RF‐2011‐02351139

Phase IV clinical trial of anti‐viral treatment for Hepatitis C infection in compensated cirrhosis

Sicilia Clinical Digestive, Kidney and Urological Systems


RF‐2011‐02348309

EXtending Computational Analysis of functionaL Images to define the total asset of Bone marrow and hematopoietic fUnction in blood disoRdes (EXCALIBUR)


Biomedical Bioengineering Sciences and Technologies

9,5Oncology

Pagina 17 di 231



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STRATEGICA

RF‐2011‐02348446

Long term mechanisms of diabetes prevention and remission after bariatric surgery: study of glucose metabolism, insulin secretion and cardiovascular risk 7 years after Roux‐en Y Gastric bypass.

Toscana Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02352881

Development Of A Novel Adoptive Cell Transfer Approach (ACT) For Cancer Immunotherapy Based On The Use Of Autologous IFN‐DC For The Induction Of Anti‐Tumor Response And Implemented By Strategies Aimed At Extending The Replicative Lifespan Of The Anti‐Tumo

ISS Biomedical Oncology 2 ‐ Translational Clinical 9,75Oncology

RF‐2011‐02352711

Search for new genetic biomarkers for early diagnosis and prevention of Familial Thoracic Aortic Aneurysms and Dissections

Emilia‐Romagna Clinical Genes, Genomes and Genetics 9,75Metabolism disorders and cardiovascular disease

RF‐2011‐02347071

Exploiting Immunoglobulin Stereotypy as a marker of prognosis and a target for therapy in Chronic Lymphocytic Leukemia


RF‐2011‐02347777

Molecular portrait of heterogeneous lesions throughout the course of bovine tuberculosis

Sardegna Biomedical Infectious Diseases and Microbiology


RF‐2011‐02347243

Genomic architecture and clonal evolution of myelodysplastic syndromes and myeloproliferative neoplasms

SAN MATTEO Biomedical Oncology 1 ‐ Basic Translational 10Oncology

RF‐2011‐02349958

Engineering Commensal Bacteria for the Delivery of Therapeutic Proteins

SAN RAFFAELE Milano Biomedical Bioengineering Sciences and Technologies


Pagina 18 di 231



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STRATEGICA

RF‐2011‐02350280

Genetic dissection of cystic fibrosis host susceptibility to Pseudomonas aeruginosa infections using a highly genetically diverse mouse resource population, the Collaborative Cross mice

SAN RAFFAELE Milano Biomedical Infectious Diseases and Microbiology


RF‐2011‐02347758

Reverse transcriptase inhibitors in an innovative anticancer therapy

ISS Biomedical Oncology 1 ‐ Basic Translational 10Oncology

RF‐2011‐02350980

Disruption of white matter integrity in bipolar disorder: changes of diffusion tensor imaging measures as markers of the biological underpinnings of the progressive deterioration of cognition and of the cognitive control of emotions.



RF‐2011‐02349918

Searching for early and predictive markers of individual risk for head and neck cancer

Toscana Biomedical Oncology 1 ‐ Basic Translational 10Oncology

RF‐2011‐02347970

Optimization of plasma progranulin dosage for predicting null progranulin mutations in neurodegenerative diseases: A pilot Multicentre Italian Study for harmonization of procedures to be translated into clinical practice.

FATEBENEFRATELLI Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02350246

Improving social dysfunction through oxytocin administration in non‐human infants exposed to maternal neglect early during postnatal life



Pagina 19 di 231



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STRATEGICA

RF‐2011‐02351875

IMPACT OF EXPOSURE TO ESTROGEN‐LIKE ENDOCRINE DISRUPTING

CHEMICALS(EEDC) ON PUBERTAL DEVELOPMENT AND ESTABLISHMENT

OF REFERENCERANGES FOR EXPOSITION IN CHILDHOOD.


Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences

10Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02349297

Genetic factors influencing early plasma ribavirin cut‐off values in HCV therapy to reduce anemia toxicity and improve outcome.

Piemonte Biomedical Infectious Diseases and Microbiology


RF‐2011‐02347141

Effect of Ag nanoparticles in controlling Salmonella and Campylobacter in laying hens and clinical and food safety insights

IZS Venezie Biomedical Veterinary 10Food safety and animal welfare

RF‐2011‐02348959

From the measure of guidelines adherence in oncology to the assessment of health system performance

Lombardia Clinical Healthcare Delivery and Methodologies

10Oncology

RF‐2011‐02348951

Innate immune response as a key factor aimed to optimize HCV patients therapy management

SPALLANZANI Biomedical Immunology 10Infection and immunity

RF‐2011‐02350484

Tumor Infiltrating Lymphocytes (TIL) and melanoma: prognostic markers and new terapeutic targets

IDI Biomedical Oncology 1 ‐ Basic Translational 10Oncology

RF‐2011‐02346880

Targeted next generation sequencing as tool for molecular diagnosis of rare anemias

Campania Biomedical Genes, Genomes and Genetics 10The new biotechnologies

Pagina 20 di 231



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STRATEGICA

RF‐2011‐02348801

THE ROLE OF SOD1 IN THE NUCLEUS: NEW INSIGHTS INTO THE PATHOGENESIS OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)

MONDINO Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02351616

Combining Unconventional T cells with Vaccination in Renal Cell Carcinoma Immunotherapy

Puglia Biomedical Oncology 2 ‐ Translational Clinical 10Oncology

RF‐2011‐02352155

modulation of HCN channels by GPR35 in chronic pain

Toscana Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02352126

DEVELOPMENT OF NOVEL ANTIBODY‐ENGINEERED GOLD NANOPARTICLES AS TARGETED DRUG DELIVERY FOR THE TREATMENT OF CHRONIC LUNG ALLOGRAFT DYSFUNCTION

Veneto Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02347986

A NEW STRATEGY FOR THE CONTROL OF RHEUMATOID ARTHRITIS: DUAL ROLE OF THE ATYPICAL CHEMOTACTIC RECEPTOR CCRL2 AS A BIOMARKER AND THERAPEUTIC TARGET

HUMANITAS Biomedical Immunology 10Infection and immunity

RF‐2011‐02348348

From lifestyle to mitochondrial benefits: study on a combined therapeutic approach to Huntington's disease



RF‐2011‐02348364

New biomarkers for early SIRS/sepsis diagnosis in pediatric and adult patiens.

Friuli‐Venezia Giulia Clinical Infectious Diseases and Microbiology


Pagina 21 di 231



SCORE.


STRATEGICA

RF‐2011‐02346886

Novel formula milks and neonatal gut microbiota: a dynamic interplay approached by systems biology



10Food safety and animal welfare

RF‐2011‐02348953

A Twist code of p53 inactivation in sarcomas: clinicopathological and therapeutic implications

C.R.O. AVIANO Clinical Oncology 1 ‐ Basic Translational 10Oncology

RF‐2011‐02351116

NEW ALLOCATION CRITERIA FOR LIVER TRANSPLANTATION IN PATIENTS WITH AND WITHOUT HEPATOCELLULAR CARCINOMA BASED ON TRANSPLANT BENEFIT PRINCIPLES: A MULTICENTER, PROSPECTIVE STUDY.

Emilia‐Romagna Clinical Healthcare Delivery and Methodologies

10Oncology

RF‐2011‐02348194

Innovative diagnostic approach for hereditary cardiomyopathies

MULTIMEDICA Clinical Genes, Genomes and Genetics 10Metabolism disorders and cardiovascular disease

RF‐2011‐02352753

MOLECULAR CHARACTERIZATION OF COXIELLA BURNETII FROM DOMESTIC RUMINANTS AND WILDLIFE SPECIES BY MLVA AND NGS TECHNIQUES

IZS Mezzogiorno Biomedical Infectious Diseases and Microbiology


RF‐2011‐02347276

Investigating the molecular mechanisms leading to genome instability in tumours:

analysis of role of the replicationstress response and its potential for early diagnosis and target therapy of cancer


RF‐2011‐02350889

Prospective Characterization of Circulating Tumor Cells in Patients with Hormone Receptor Positive Metastatic Breast Cancer

I.E.O. Clinical Oncology 2 ‐ Translational Clinical 10Oncology

Pagina 22 di 231



SCORE.


STRATEGICA

RF‐2011‐02350578

IDENTIFICATION OF EPILEPTOGENIC NETWORKS IN SURGICAL EPILEPSIES BY A NON‐INVASIVE MULTIMODAL APPROACH

CARLO BESTA Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349798

Epithelial ovarian cancer: affecting tumor growth by targeting aberrant metabolism.

IST.TUMORI MILANO Biomedical Oncology 2 ‐ Translational Clinical 10Oncology

RF‐2011‐02346750

The extracellular matrix protein EMILIN1 as a novel structural and functional determinant of lymphangiogenesis and lymphedema

C.R.O. AVIANO Biomedical Vascular and Hematology 10Oncology

RF‐2011‐02347603

Nationwide study on trends in hospital admissions for major cardiovascular events and procedures among people with and without diabetes in Italy, 2001‐2010

Piemonte Clinical Healthcare Delivery and Methodologies


RF‐2011‐02352383

Effects of Tumor‐associated Fibroblast and hypoxia on the availability of efficient NK cells within the tumor core: characterization of molecular targets for therapy in melanoma and colon cancer.


Biomedical Immunology 10Oncology

RF‐2011‐02347260

In vivo toxi‐omic signatures for brain and thyroid function: combined exposure to

mixtures of endocrine disruptingchemicals and iodine deficiency in animal models and translation to epidemiological/clinical

studies

ISS Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02347402

Non‐invasive assessment of liver steatosis and fibrosis in pediatric patients

SAN MATTEO Clinical Digestive, Kidney and Urological Systems


Pagina 23 di 231



SCORE.


STRATEGICA

RF‐2011‐02350598

MicroRNA Signature of Vascular Complications in Type 1 Diabetes



RF‐2011‐02351315

HPV positive oropharyngeal cancer: characterization of immunological and viral profiles, and their role in the response to treatment

SAN MATTEO Clinical Oncology 2 ‐ Translational Clinical 10Oncology

RF‐2011‐02347283

Breast cancer with low risk of local recurrence: 3D Conformal Accelerated and Hypofractionated Partial Breast Irradiation vs. standard whole breast radiotherapy after conservative surgery

Emilia‐Romagna Clinical Oncology 2 ‐ Translational Clinical 10Oncology

RF‐2011‐02351432

The complement and coagulation systems as therapeutic targets in subarachnoid hemorrhage: studies in patients and in experimental models.

MAGGIORE Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02347262

RESPONSE ORIENTED MAINTENANCE IMMUNOTHERAPY IN PATIENTS WITH FOLLICULAR LYMPHOMA.


RF‐2011‐02347359

Comparative analysis of genomic and epigenomic alterations induced by leukemogenic AML1‐fusion proteins

I.E.O. Biomedical Oncology 1 ‐ Basic Translational 10Oncology

RF‐2011‐02347522

Genetic markers in elderly to estimate the risk for vascular diseases by using the peripheral arterial disease model.

Sicilia Biomedical Genes, Genomes and Genetics 10,25Metabolism disorders and cardiovascular disease

Pagina 24 di 231



SCORE.


STRATEGICA

RF‐2011‐02347553

A phase II, randomised, placebo‐ controlled trial of neuroprotection with Raltegravir in

Secondary Progressive Multiple Sclerosis



RF‐2011‐02350801

Implementation of Chronic Care Model, using Tele‐care and Home care, in patients with multiple comorbidities: evaluation of the cost‐effectiveness and quality of life



RF‐2011‐02347532

A multi‐site international RCT comparing regional and general anesthesia in infants for effects on neurodevelopmental outcome at five year of age: The GAS Trial.

GASLINI Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02350214

Muscle imaging in neuromuscular disorders: conventional, high and ultrahigh field imaging studies for coming into a focus

STELLA MARIS Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02351947

The molecular basis of cognitive impairment in Williams‐Beuren Syndrome: a cell reprogramming‐based approach


Biomedical Genes, Genomes and Genetics 10,5Neurological diseases

RF‐2011‐02347422

Naturally occurring and re‐programed cancer stem cells in ovarian carcinoma: functional role and clinical implications.


RF‐2011‐02352440

Autonomic cardiovascular evaluation in low respiratory tract infections

MAGGIORE Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02352328

Assessing colorectal cancer risk: are DNA viruses and genetic damage in circulating cells valuable biomarkers?

Emilia‐Romagna Biomedical Oncology 1 ‐ Basic Translational 10,5Oncology

Pagina 25 di 231



SCORE.


STRATEGICA

RF‐2011‐02347127

Genomic approach for motor neuron diseases



RF‐2011‐02350439

TRAIL‐producing UC‐MSCs as cytotherapy to defeat multiple myeloma: a preclinical study.

ONCOLOGICO DI BARI Biomedical Oncology 2 ‐ Translational Clinical 10,5Oncology

RF‐2011‐02350623

Paratuberculosis in sheep and goats herds in Calabria and human exposure to Mycobacterium avium subspecies paratuberculosis (MAP) trough dairy products


RF‐2011‐02347060

Surveillance of the circulation of rotaviruses in the infantile population of Sicily following the introduction of rotavirus vaccination

Sicilia Biomedical Infectious Diseases and Microbiology


RF‐2011‐02350640

Investigation on the sensitivity of dorsal raphe serotonergic neurons to hypercapnic stimuli in a transgenic mouse model of Sudden Infant Death Syndrome (SIDS) characterized by selective alteration of serotonergic neuron autoinhibition.



RF‐2011‐02352520

Project Title: Endoscopic Screening and onCologic appropRiate rEmoval of Early colorectal lesioNs. ENDOSCREEN

Piemonte Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02348282

Studying the tumor microenvironment to find new therapeutic targets and strategies in Hodgkin lymphoma:the role of Mesenchymal stem cells

C.R.O. AVIANO Biomedical Oncology 1 ‐ Basic Translational 10,5Oncology

Pagina 26 di 231



SCORE.


STRATEGICA

RF‐2011‐02350613

High‐throughput mutation profiling of Sézary Syndrome: implications for pathogenesis, classification, and potential therapeutic developments.

IDI Biomedical Oncology 1 ‐ Basic Translational 10,5Oncology

RF‐2011‐02352036

METABOHEARTFAIL‐GRAPE miRNAs IN REVERSING REMODELING THROUGH MODULATION OF CARDIAC AQUAPORIN‐7 AND GLYCEROL UPTAKE IN A SWINE MODEL OF NON‐ISCHEMIC

CHRONIC HEART FAILURE

Toscana Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02349080

Brain Mechanisms of Chronic Subjective Dizziness



RF‐2011‐02346764

TRIMming away HIV‐1. infection Role of TRIM proteins in establishement and maintenance of HIV‐1 latency

SAN RAFFAELE Milano Biomedical AIDS and Related Research 10,5Infection and immunity

RF‐2011‐02351656

GISSI Outliers ‐ The CAPIRE (Coronary Atherosclerosis in outlier subjects: Protective and Individual Risk factor Evaluation) study ‐ The Life Style sub‐study

MAUGERI Biomedical Risk, Prevention and Health Behavior


RF‐2011‐02346871

Exploiting neural stem cell‐targeted mouse models for improving the understanding of the pathogenetic mechanisms underlying Tuberous Sclerosis Complex and developing novel therapeutic approaches.



RF‐2011‐02347571

Cell senescence and age‐dependent decrease in heart function: role of HMGB1 protein

IDI Biomedical Biology of Development and Aging 10,5Metabolism disorders and cardiovascular disease

Pagina 27 di 231



SCORE.


STRATEGICA

RF‐2011‐02352686

Understanding Pancreatic Acinar Cell Carcinoma for better understanding Pancreatic Ductal Carcinoma


RF‐2011‐02346990

Development of a service interface method ( WebService) beetween family care physicians operating in a primary care setting and nephrologists , for the prevention, diagnosis and treatment of kidney damage in patients with type II diabetes mellitus .

Toscana Clinical Digestive, Kidney and Urological Systems


RF‐2011‐02351728

Containment of a region‐wide outbreak of Carbapenem‐resistant Klebsiella pneumoniae in seven lombardian hospital: molecular characterization, epidemiology and outcome.

Lombardia Clinical Infectious Diseases and Microbiology


RF‐2011‐02349240

Dynamics of epigenetic landscape during phase‐specific colorectal cancer reprogramming of stem cells and tissues in a murine stress related carcinogenesis model and human tumor biopsies.



RF‐2011‐02349381

MicroRNAs regulated by mutated p53 oncoproteins in colon cancer

REGINA ELENA Biomedical Oncology 1 ‐ Basic Translational 10,5Oncology

RF‐2011‐02347753

Genetic manipulation of embryonic stem cells and induced pluripotent stem cells (ES and iPS) for endorsing cardiac fate toward beating cardiomyocytes: novel strategies for cardiac regeneration in myocardial infarction.

NEUROMED Biomedical Cardiovascular and Respiratory Sciences


Pagina 28 di 231



SCORE.


STRATEGICA

RF‐2011‐02347686

Food safety of bivalve molluscs: Development and application of molecular tools for identification, quantification and evaluation of antibiotic resistance and virulence potential of food‐associated enteric and autochthonous bacterial

pathogens

IZS Umbria e delle Marche Biomedical Veterinary 10,5Food safety and animal welfare

RF‐2011‐02350566

MicroRNA regulation in the pathogenesis of MD and in the mechanism of action of antidepressant drugs



RF‐2011‐02347244

Dissecting the genetic etiology of epileptic encephalopathies by high‐throughput sequencing

GASLINI Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02350571

Heterotypic interactions in thrombo‐inflammatory processes associated with the thrombotic vascular occlusion in

sepsis:the role of vitamin K‐dependent protein C


RF‐2011‐02347340

Pre‐clinical evaluation of safety and efficacy of intra‐arterial infusion of mesenchymal stems cells in experimental models

ofneurodegenerative parkinsonisms and analysis of potential therapeutic mechanisms: en route for a clinical trial

MONDINO Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02346822

One or more beta‐amyloids? Links between amyloid composition and phenotypic heterogeneity in Alzheimer's disease: implications for diagnosis and therapy

CARLO BESTA Biomedical Brain Disorders and Clinical Neuroscience


Pagina 29 di 231



SCORE.


STRATEGICA

RF‐2011‐02348713

Genetic variability of Mycobacterium tuberculosis and its implications for transmission dynamics, pathogenesis and immune response



RF‐2011‐02347356

PHARMACOGENOMICS OF HYPERTENSION: A NEW APPROACH FOR A PERSONALIZED MEDICINE

SAN RAFFAELE Milano Clinical Digestive, Kidney and Urological Systems


RF‐2011‐02348075

Regulation of SMN2 splicing: implications for novel therapeutic approaches to Spinal Muscular Atrophy

SANTA LUCIA Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02347365

From breast to brain: study of the molecular mechanisms mediating the development of brain metastasis


RF‐2011‐02352809

Role of mast cells in the pathogenesis of diabetic heart disease.

SAN RAFFAELE Milano Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02346983

Investigation on the role of iron and mitochondria in neurodegenerative disorders through the development of new human neuronal cellular systems



RF‐2011‐02346800

A new predictive assay to assess the efficacy of combinatorial treatments against stem cells enriched cultures from metastatic melanoma patients

PASCALE Biomedical Oncology 1 ‐ Basic Translational 10,5Oncology

RF‐2011‐02349138

Rethinking neuroinflammation in sporadic AD: exploring novel pathways to boost endogenous neuroprotective mechanisms



Pagina 30 di 231



SCORE.


STRATEGICA

RF‐2011‐02352191

Structural imaging in systemic amyloidosis: an inescapable step toward the optimization and validation of more effective therapeutic approaches

SAN MATTEO Biomedical Biological Chemistry and Macromolecular Biophysics


RF‐2011‐02349156

DEVELOPMENT OF AN EXOSOME BASED IN‐VIVO TEST TO DETECT PRIONS IN BLOOD



RF‐2011‐02350708

Development of miniaturized assays for the timely diagnosis of rare diseases

Piemonte Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02349089

Rescue of Transforming‐Growth‐Factor‐beta 1 signaling as a new strategy for neuroprotection in Alzheimer's disease: role of antidepressant drugs

OASI MARIA S.S. Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02347827

Unravelling the genetic basis of variable clinical expression in NF1: use of an integrated next generation sequencing platform to identify novel disease‐causing and modifier genes.


Biomedical Genes, Genomes and Genetics 10,75Oncology

RF‐2011‐02349204

MITOCHONDRIA AND AUTOPHAGY IN DEGENERATIVE SYNAPSES



RF‐2011‐02346959

Evaluation of the efficacy of Rapamycin and a DPP‐4 inhibitor (Vildagliptin) in improving beta cell function in type 1 diabetes of long duration, a perspective randomized study

SAN RAFFAELE Milano Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


Pagina 31 di 231



SCORE.


STRATEGICA

RF‐2011‐02352442

Long¿term exposure to ambient air pollution and pregnancy outcomes in women of three large Italian longitudinal studies

Lazio Clinical Population Sciences and Epidemiology


RF‐2011‐02351880

Evaluation of anti‐NA antibodies as possible correlates of protection from influenza disease: development of serological assays designed to detect a truly functional antibody response to influenza vaccination, with specific regard to the anti‐NA

ISS Biomedical Immunology 11Infection and immunity

RF‐2011‐02347399

Senescence‐Associated microRNAs (SAmiRs) in cellular senescence and organismal aging

SDN Biomedical Biology of Development and Aging 11Neurological diseases

RF‐2011‐02348370

Postural sway and facial mimicry as behavioral markers of covert motor symptoms in Parkinson's disease in a new differential early diagnostic protocol.

SANTA LUCIA Biomedical Biobehavioral and Behavioral Processes


RF‐2011‐02349811

The use of top soils improvers from municipal wastewater treatment plants, on pasture: risk assessment of the associated microbial and organic chemical contamination on grazing food producing animals, and on food safety and food security (SOIL‐SAFE)

ISS Biomedical Veterinary 11Food safety and animal welfare

RF‐2011‐02351113

Fighting impaired blood flow and supporting skeletal muscle regeneration in diabetes and peripheral artery disease (PAD): an approach based on unacylated ghrelin (UAG) administration

Piemonte Biomedical Vascular and Hematology 11Metabolism disorders and cardiovascular disease

Pagina 32 di 231



SCORE.


STRATEGICA

RF‐2011‐02350906

'Septosomes': System Biology and Pathogenetic Role of Exosomes in Sepsis‐associated Immune‐paralysis and Organ Failures

Piemonte Biomedical Immunology 11Infection and immunity

RF‐2011‐02350875

Use of Limbal Adult Stem Cells for Osteo and Condrocyte Differentiation and Application in Bone and in Cartilage Regeneration and Tissue Engineering (ABADIR PROJECT)

Sicilia Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351077

Dissecting the pathogenesis and possible reversibility of cachexia in end‐stage chronic heart failure

Sicilia Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02346917

Transcriptomic profiling in circulating mesenchymal stem cells of patients with degenerative diseases.

Veneto Biomedical Genes, Genomes and Genetics 11Metabolism disorders and cardiovascular disease

RF‐2011‐02348826

Fertility preservation in gonadotoxic treatments


RF‐2011‐02350733

Co‐transcriptional and post‐transcriptional regulation of gene expression by EWS and EWS‐FLI1 in the pathogenesis of Ewing's Sarcoma

SANTA LUCIA Biomedical Oncology 1 ‐ Basic Translational 11Oncology

RF‐2011‐02346984

Identification of new therapeutical targets of cancer stem cells: study of the mechanistics of mitotic spindle alignment to cortical polarity in mammary stem cell asymmetric divisions

I.E.O. Biomedical Biological Chemistry and Macromolecular Biophysics

11Oncology

Pagina 33 di 231



SCORE.


STRATEGICA

RF‐2011‐02350341

Early treatment of exercise‐induced pulmonary hypertension in systemic sclerosis

Toscana Clinical Immunology 11Infection and immunity

RF‐2011‐02346986

TRAIL receptor embedding in membrane rafts could predict cancer cell susceptibility to TRAIL‐based molecularly targeted therapy

ISS Clinical Oncology 2 ‐ Translational Clinical 11Oncology

RF‐2011‐02349088

A translational approach to hereditary neuropathies


Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02347873

Cord blood expanded endothelial progenitors in patients with no‐option critical limb ischemia.

Lazio Biomedical Vascular and Hematology 11Metabolism disorders and cardiovascular disease

RF‐2011‐02350673

Screening for Autoimmune Polyglandular Syndrome Type 2 in patients with autoimmune thyroiditis: definition of methodology and cost‐benefit analysis.



RF‐2011‐02350488

Imaging the fate of stem cells in vivo by near infrared technology: a translational study for longitudinal tracking in a rodent model of Parkinsons disease

AUXOLOGICO Biomedical Emerging Technologies and Training in Neurosciences


RF‐2011‐02347867

Treatment of therapy‐refractory cancer in patients affected by Swachman Diamond syndrome or related inherited diseases due to alterations of the ribosomal apparatus.

SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 11Oncology

Pagina 34 di 231



SCORE.


STRATEGICA

RF‐2011‐02347616

The role of CRPs and SIRTs in modulating cellular stress response after myocardial infarction.




RF‐2011‐02350999

Early identification of left ventricular dysfunction due to anthracyclines and target‐therapy: role of novel imaging techniques and microRNA.

PASCALE Biomedical Cardiovascular and Respiratory Sciences

11Oncology

RF‐2011‐02346770

Clinical and healthcare strategies for improving quality of life in persons affected by spinal cord injuries: Tuscany

regionalnetwork and use of innovative technological devices



RF‐2011‐02349125

Follow up study of the relationship between telomere length and the onset of diabetic complications

I.N.R.C.A. Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351193

NETWORK DEGENERATION IN MOTOR NEURON DISEASES (MND): A STUDY OF THE STRUCTURAL AND FUNCTIONAL CONNECTOMES IN AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MND



RF‐2011‐02349948

Investigation of genetic molecular mechanisms underlying the risk of cardiovascular events: role of rs5065 human atrial natriuretic peptide gene variant

NEUROMED Biomedical Genes, Genomes and Genetics 11Metabolism disorders and cardiovascular disease

RF‐2011‐02347894

A new vaccine design to eliminate CCR5 expression and prevent HIV infection

SAN RAFFAELE Milano Biomedical AIDS and Related Research 11Infection and immunity

Pagina 35 di 231



SCORE.


STRATEGICA

RF‐2011‐02351863

Identification of Determinants of Healthy Aging in Italy (IDAGIT)

CARLO BESTA Clinical Population Sciences and Epidemiology


RF‐2011‐02347242

Enhancement of NKG2D ligands‐induced anti‐tumor response in Hodgkin and non Hodgkin lymphomas: ERp5 thiol isomerase and ADAM10 disintegrin‐metalloproteinase as possible therapeutic targets.

SAN RAFFAELE Milano Biomedical Immunology 11Oncology

RF‐2011‐02349443

Integrated diagnostic evaluation of PET/RM and molecular markers in the diagnosis of bone lesions

SDN Clinical Oncology 2 ‐ Translational Clinical 11Oncology

RF‐2011‐02348984

Next Generation Sequencing (NGS): from basic research to diagnostic tool for nephrotic syndrome.

Puglia Biomedical Genes, Genomes and Genetics 11The new biotechnologies

RF‐2011‐02350615

Characterization of the role of Mycobacterium avium subspecies paratuberculosis (Map) as a trigger in Type 1 Diabetes



RF‐2011‐02352834

Development and evaluation of Influenza Virus Polymerase Inhibitors for combination antiviral therapy



RF‐2011‐02347169

MECHANISMS REGULATING DENDRITIC CELL PROTUMORAL ACTIVITY WITHIN THE HYPOXIC MICROENVIRONMENT: POTENTIAL THERAPEUTIC APPLICATIONS IN NEUROBLASTOMA

GASLINI Biomedical Oncology 1 ‐ Basic Translational 11Oncology

Pagina 36 di 231



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STRATEGICA

RF‐2011‐02347908

Prospective validation of predictive biomarkers in elderly patients with non‐small‐cell lung cancer

PASCALE Biomedical Oncology 2 ‐ Translational Clinical 11Oncology

RF‐2011‐02352056

A randomized intervention study to assess the effect of the Mediterranean Diet on the plasma fatty acid profile.

MONZINO Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02349412

Modulation of the metabotropic glutamate receptor 1 as a novel strategy to treat nephrotic syndrome.

MAGGIORE Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02346763

Positive selection, expansion and transplantation of regulatory T cells (Tregs) to prevent cellular rejection and to induce tolerance in solid organ transplantation.

Emilia‐Romagna Clinical Immunology 11The new biotechnologies

RF‐2011‐02348235

Molecular pathologies and functional interactions of the CDKL5 and MECP2 genes involved in a large spectrum of neuro‐psichiatric diseases



RF‐2011‐02347456

ROLE OF THE NEUROTROPHIN BDNF AND ITS INTERACTION WITH ENVIRONMENTAL FACTORS IN THE REGULATION OF THROMBOSIS

MONZINO Biomedical Vascular and Hematology 11Metabolism disorders and cardiovascular disease

RF‐2011‐02349645

Early diagnosis, tumor response to neoadjuvant treatments and diagnosis of

tumor recurrence using new andnon‐invasive biomarkers in colon and rectal cancer

I. O. V. Clinical Oncology 2 ‐ Translational Clinical 11Oncology

Pagina 37 di 231



SCORE.


STRATEGICA

RF‐2011‐02347166

PREVENTION OF MOTHER‐TO‐CHILD TRANSMISSION OF HIV: SAFETY, EFFICACY AND ACCEPTABILITY OF THE ADMINISTRATION OF TENOFOVIR, LAMIVUDINE AND EFAVIRENZ WITHIN A LIFELONG TREATMENT STRATEGY FOR ALL PREGNANT WOMEN WITH HIV


RF‐2011‐02350082

The "TRIPL‐A Study". A TRIal to promote PhysicaL Activity among patients in the young‐old age affected by Type 2 diabetes

I.N.R.C.A. Clinical Risk, Prevention and Health Behavior


RF‐2011‐02349303

Impact of deep Transcranic Magnetic Stimulation (TMS) on satiety and weight control

SAN DONATO Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02350814

Molecular and cellular mechanisms of vestibular compensation

Piemonte Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02349953

PROMOTING MOTOR RE‐LEARNING IN PATIENTS WITH STROKE BY ENHANCING NON INVASIVELY ASSOCIATED CEREBELLAR‐CORTICAL PLASTICITY.

SANTA LUCIA Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02350243

Targeting the CCR2 and CCL2 system to modulate macrophage recruitment and polarization in amyotropic lateral sclerosis

HUMANITAS Biomedical Immunology 11,5Infection and immunity

RF‐2011‐02346773

Development of a therapeutic approach against HIV/AIDS combining the delivery of single‐chain Fv antibodies and transcription activator like effector protein.

ISS Biomedical AIDS and Related Research 11,5The new biotechnologies

Pagina 38 di 231



SCORE.


STRATEGICA

RF‐2011‐02351164

Hypothyroidism and Endometrial function during Blastocyst Implantation.

Lazio Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351812

APPLICATIONS OF ULTRASTRUCTURAL CELL ANALYSIS IN THE FIELD OF REPRODUCTIVE TECHNOLOGIES

BURLO GAROFALO Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351688

Development of a biotech system for natural compound production, by plant in vitro tissue culture, for the prevention and treatment of human dismetabolic diseases.



RF‐2011‐02348728

Sonic hedgehog signaling and cholesterol dishomeostasis at the primary cilium in Niemann Pick C disease: implications for therapy

Friuli‐Venezia Giulia Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349114

Dissecting the interplay between ERK and JNK signalling in the brain. From basic mechanisms to new therapeutic approaches against neurodenegerative disorders.



RF‐2011‐02349413

Development of nanostructured biomimetic nerve scaffolds



RF‐2011‐02348876

Novel mechanisms mediated by nicotinic acetylcholine receptors, and interactions with nuclear PPARalpha, in the neuropathogenesis of epilepsy: preclinical and translational studies

Sardegna Biomedical Brain Disorders and Clinical Neuroscience


Pagina 39 di 231



SCORE.


STRATEGICA

RF‐2011‐02351659

Assessing the exposure of children and other vulnerable population groups to priority dietary contaminants


RF‐2011‐02350134

Discovery of Tat mimicking compounds to fight HIV latency


RF‐2011‐02349133

EMERGING NOROVIRUS MUTANT AND RECOMBINANT STRAINS: A MOLECULAR EPIDEMIOLOGICAL INVESTIGATION ON SEWER SYSTEMS AND HOSPITALIZED PATIENTS



RF‐2011‐02350520

Recurrent herpes virus infections as risk factor for Alzheimer`s disease


Biomedical Infectious Diseases and Microbiology


RF‐2011‐02351964

Characterization and rescue of impaired dopaminergic signaling in primary torsion dystonia



RF‐2011‐02348296

Tuberculosis in HIV/AIDS patients: genetic diversity and drug‐resistance of clinical isolates of Mycobacterium tuberculosis

Toscana Biomedical AIDS and Related Research 11,5Infection and immunity

RF‐2011‐02350445

Autoreactive T cell expansion under the influence of interleukin‐7 in patients with type I diabetes during beta cell replacemement therapy


RF‐2011‐02350491

Role of the miR‐132~212 cluster in B‐cell receptor signaling in chronic lymphocytic leukemia: novel targets with therapeutic potential

C.R.O. AVIANO Biomedical Oncology 1 ‐ Basic Translational 11,5Infection and immunity

Pagina 40 di 231



SCORE.


STRATEGICA

RF‐2011‐02347099

The MINA PROJECT. Mirror Neurons In Alcoholics: can Mirror Neuron System help us to understand and treat Alcohol Addiction?



RF‐2011‐02352119

In vivo generation of Tregs with differential homing capabilities for dissociating the antitumor effects of clinical hematopoietic stem cell transplantation from graft‐versus‐host disease

SAN RAFFAELE Milano Biomedical Immunology 11,5Oncology

RF‐2011‐02348397

Astrocyte TRK on demyelination SAN RAFFAELE Milano Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02348103

Genetic and antigenic diversity and pathogenicity of viruses associated with enteritis

Emilia‐Romagna Biomedical Infectious Diseases and Microbiology


RF‐2011‐02352636

The availability of "old" and "new" drug eluting stents in routine clinical practice: influence on the treatment choice among medical therapy vs. percutaneous coronary interventions vs. coronary by‐pass surgery and on 4‐year clinical outcome in patients w

Veneto Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02350984

Intraventricular injection of Peripheral Blood Stem Cells during coronary artery bypass grafting in patients with heart failure induced by previous myocardial infarction.

Campania Clinical Cardiovascular and Respiratory Sciences


Pagina 41 di 231



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STRATEGICA

RF‐2011‐02351933

SMART FOOD AND LIFESTYLE INTERVENTIONS FOR HEALTHY BRAIN

AGING.Developing a comprehensive protocol to assess the preventive effects of lifestyle interventions on food habits, physical and cognitive activity and social and cultural participation on cognit



RF‐2011‐02347955

A multicenter prospective study on inflammatory/infectious CNS diseases in different immunological settings: a multidisciplinary approach using an online data base

MONDINO Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02347690

Pyrimethamine derivatives: a new generation of antifolate drugs for treatment of metastatic melanoma. A

prepreclinicalstudy.

ISS Biomedical Oncology 1 ‐ Basic Translational 11,5Oncology

RF‐2011‐02347254

Targeting leukemia cells by CD1c‐restricted autoreactive T cell response


RF‐2011‐02347403

The tumor cell spheroid as a key factor in the drug resistance and dissemination of high grade ovarian serous carcinoma (sEOC)


RF‐2011‐02347280

Morphofunctional visual pathways evaluation in multiple sclerosis: possible identification of neurodegenerative bio‐markers

BIETTI Clinical Integrative, Functional, and Cognitive Neuroscience


Pagina 42 di 231



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STRATEGICA

RF‐2011‐02350517

Inflammatory mechanisms underlying cortico‐hippocampal hyperexcitability in Alzheimer's disease: from in vitro and in vivo murine models to patient



RF‐2011‐02351069

CDCP1 as a Therapeutic Target in Triple‐Negative Breast Cancer

IST.TUMORI MILANO Biomedical Oncology 2 ‐ Translational Clinical 11,5Oncology

RF‐2011‐02350309

Improving Prognostic Accuracy in Severe Traumatic Brain Injury with Diffusion Tensor Imaging MRI Combined with Cerebral Microdialysis Measurements of Axonal Proteins



RF‐2011‐02348920

Analysis of the role of different isoforms of thymic stromal lymphopoietin and the microbiota in T cell activation in inflammatory conditions of the gut

I.E.O. Clinical Immunology 11,75Infection and immunity

RF‐2011‐02351200

Colonization and infection by extensively‐drug resistant carbapenemase‐producing Enterobacteriaceae: towards a better understanding of the emergence and dynamics of colonization within the complex ecosystem of the human gut microbiome, of relationships be

Toscana Biomedical Infectious Diseases and Microbiology


RF‐2011‐02350164

Food nanomaterials exposure assessment ISS Biomedical Veterinary 11,75Food safety and animal welfare

Pagina 43 di 231



SCORE.


STRATEGICA

RF‐2011‐02347709

Identification of Biomarkers for Non Melanoma Skin Cancers in a Multicenter Cohort of Kidney Transplant Recipients: Evaluation of Ethiopatogenetic Role and Clinical Implications.

Piemonte Clinical Oncology 2 ‐ Translational Clinical 11,75Oncology

RF‐2011‐02347956

Role of ATM kinase in cerebellum development, homeostasis and function: implications for Ataxia Telangiectasia and other cerebellar disorders



RF‐2011‐02352294

CIRCULATING CELL‐FREE BIOMARKERS IN THE DIAGNOSIS AND FOLLOW UP OF DIFFERENTIATED THYROID CANCER

Toscana Clinical Oncology 2 ‐ Translational Clinical 12Oncology

RF‐2011‐02349478

A multiparametric approach based on clinical, biochemical, genetic and neuroimaging data to predict cognitive impairment in Parkinson's disease




RF‐2011‐02348600

Role of Neutrophil activation and NET formation in venous thromboembolic disease

Veneto Biomedical Vascular and Hematology 12Metabolism disorders and cardiovascular disease

RF‐2011‐02348213

Neurophysiological approach to evaluate cerebro‐cerebellar interactions. Characterization of a cerebellar connectivity EEG index.



RF‐2011‐02350732

ANTI‐HPV CANCER THERAPY BY ENGINEERED EXOSOMES

INCORPORATING siRNAs AND miRNAs

ISS Biomedical Bioengineering Sciences and Technologies

12Oncology

Pagina 44 di 231



SCORE.


STRATEGICA

RF‐2011‐02347106

Development of high throughput, integrated and cost‐effective molecular diagnostic tests for the detection of genetic and epigenetic defects involved in human disease

MAGGIORE Clinical Genes, Genomes and Genetics 12The new biotechnologies

RF‐2011‐02347560

Discovering metabolomic signatures associated with specific gene mutations in melanoma and their role in tumor

radiosensitivity and immunogenicity


RF‐2011‐02347557

Role of chronic inflammation in the pathogenesis of Philadelphia‐negative myeloproliferative neoplasms (MPNs): an in vitro and in vivo biomolecular and functional analysis of the stem/progenitor and megakaryocytic cell compartments

Emilia‐Romagna Biomedical Cell Biology 12Oncology

RF‐2011‐02351833

Cardiac natriuretic peptides, human adipocytes, hypertension and dysmetabolism: in‐depth in vitro analysis and clinical study in elderly patients with type 2 diabetes mellitus or chronic heart failure



RF‐2011‐02352136

Unravelling the interplay between Helicobacter pylori and the host. Biomarkers and diagnostic tools for evaluation of H. pylori‐infected patients.



RF‐2011‐02350888

Immunomodulation by mesenchymal stem cells as a potential therapeutic strategy for endometriosis.

SAN RAFFAELE Milano Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


Pagina 45 di 231



SCORE.


STRATEGICA

RF‐2011‐02347736

CLINICAL AND MOLECULAR STUDIES OF NEXT‐GENERATION IN HEREDITARY SPASTIC PARAPLEGIAS

STELLA MARIS Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02351475

Targeting streptococcal infections in the management of patients with psoriasis

Toscana Clinical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02347738

Transcritpional regulation of skeletal muscle muscle maturation and degeneration: new potential targets for therapies against muscle wasting caused by neurogenic disorders and aging.

SANTA LUCIA Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02350542

Targeting late recurrence after adjuvant treatment for early breast cancer


RF‐2011‐02349367

White Blood Cells expression profiles as a tool for predicting Metformin Efficacyin

Patients with Type 2 Diabetes


Biomedical Genes, Genomes and Genetics 12Metabolism disorders and cardiovascular disease

RF‐2011‐02349439

Molecular imaging and genome wide analysis: an integrated approach to identify early diagnostic biomarkers.


RF‐2011‐02347694

Therapeutic correction of mis‐spliced RNA transcripts and of protein conformational defects in Lysosomal Storage Disorders

Toscana Clinical Genes, Genomes and Genetics 12Metabolism disorders and cardiovascular disease

RF‐2011‐02349170

EFFECTS OF ADALIMUMAB ON PATIENT SERUM CAPACITY TO LOAD AND DISCHARGE MACHROPHAGES WITH CHOLESTEROL

Lombardia Biomedical Immunology 12Infection and immunity

Pagina 46 di 231



SCORE.


STRATEGICA

RF‐2011‐02349223

ADOPTIVE IMMUNOTHERAPY FOR METASTATIC COLORECTAL CANCER PATIENTS

Lombardia Biomedical Oncology 2 ‐ Translational Clinical 12Oncology

RF‐2011‐02352236

Identifying low‐value health care interventions for patients with neurodegenerative diseases of the Central Nervous System and Stroke to support disinvestment decisions



RF‐2011‐02346810

Study of the mechanisms responsible for the increased cancer risk and reduced tumour sensitivity in obese and diabetic type 2 people: role of the interleukin 6

Emilia‐Romagna Biomedical Oncology 1 ‐ Basic Translational 12Oncology

RF‐2011‐02347168

NSD1 PHD fingers as potential targets for Acute Myeloid Leukemia

SAN RAFFAELE Milano Biomedical Biological Chemistry and Macromolecular Biophysics

12Oncology

RF‐2011‐02349395

Role of IP‐10 and its truncated form in the pathogenesis of tuberculosis



RF‐2011‐02347086

Characterization of HIV‐related mechanisms involved in the development of Burkitt's lymphoma

Emilia‐Romagna Biomedical AIDS and Related Research 12Infection and immunity

RF‐2011‐02347227

BIOLOGICAL APPROACH TO DECONTAMINATION OF BIVALVE MOLLUSCS FROM V.PARAHAEMOLYTICUS AND SALMONELLA BY MARINE BDELLOVIBRIO‐AND‐LIKE ORGANISMS

(BALOs).

IZS Umbria e delle Marche Biomedical Veterinary 12Food safety and animal welfare

Pagina 47 di 231



SCORE.


STRATEGICA

RF‐2011‐02348800

Unravelling the genetics of Autosomal Dominant Diabetes Mellitus of the Adulthood



RF‐2011‐02350666

Can mental training based on motor imagery speed up the rehabilitation of walking? Efficacy of a controlled procedure and neurofunctional bases of recovery in patients with total knee arthroplasty

GALEAZZI Clinical Biobehavioral and Behavioral Processes


RF‐2011‐02347475

DNA vaccines coding for chimeric human/rat HER‐2 as innovative immunotherapeutic tools for the treatment of HER‐2+ cancer patients

Piemonte Biomedical Oncology 2 ‐ Translational Clinical 12Oncology

RF‐2011‐02348878

A FoxO1 metabolomics signature to identify patients at risk for major cardiovascular events: studies in human subjects with diabetes and atherosclerosis


RF‐2011‐02348873

Overcoming Anti‐Angiogenic Therapy Resistance: Investigation of MICAL2 as a Predictive Marker and Molecular Target in Cancer Therapy

Toscana Biomedical Oncology 2 ‐ Translational Clinical 12Oncology

RF‐2011‐02349772

Functional topography of the spinal motor output after spinal cord injury



RF‐2011‐02350903

Medication overuse headache as a form of dependence



Pagina 48 di 231



SCORE.


STRATEGICA

RF‐2011‐02351145

A novel in‐vivo diagnostic test for Creutzfeldt‐Jakob disease (CJD) patients by nasal brushing



RF‐2011‐02348334

Role of exosomes in pericardial fluid‐ mediated cardiac regeneration.




RF‐2011‐02347420

Monitoring disease progression and phenotypic heterogeneity in hereditary ataxias: clinical, cognitive, neuroimaging, and neurophysiological study to identify early markers of cerebellar dysfunction in patients and presymptomatic carriers



RF‐2011‐02351306

Role of autophagy impairment in the progression from steatohepatitis to hepatocarcinoma in Hepatitis C patients.

SPALLANZANI Biomedical Infectious Diseases and Microbiology


RF‐2011‐02350193

Assessment of strategies for identifying undiagnosed type 2 diabetes mellitus

Veneto Clinical Population Sciences and Epidemiology


RF‐2011‐02350374

Effects of action observation therapy on rehabilitation of motor deficits of the dominant right upper limb in patients with MS: a study with structural and functional MRI.



RF‐2011‐02350220

Roles of mesopontine‐subthalamic nucleus projections in the control of basal ganglia functions and in Parkinson disease

Lazio Biomedical Brain Disorders and Clinical Neuroscience


Pagina 49 di 231



SCORE.


STRATEGICA

RF‐2011‐02350369

Biomechanical Characterization of carotid Plaque by Innovative Ultrasound in Stroke (BioCaPS)

Toscana Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02350898

Cardiotrophin‐1 as a biomarker of left ventricular dysfunction in Hypertensive Heart Disease

AUXOLOGICO Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02351930

Use of RNA aptamers as a novel tool for targeting Tumor Educated Myeloid Cells to control metastatic disease

I. O. V. Biomedical Oncology 1 ‐ Basic Translational 12Oncology

RF‐2011‐02348944

Identification and validation of novel biomarkers for Multiple Sclerosis and Alzheimer's Disease



RF‐2011‐02351021

Modeling and taming the genotoxicity of viral vector integration

SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 12The new biotechnologies

RF‐2011‐02346914

Phase 1/2 study of valproic acid and short‐course radiotherapy plus capecitabine as preoperative treatment in low‐moderate risk rectal cancer

PASCALE Clinical Oncology 2 ‐ Translational Clinical 12Oncology

RF‐2011‐02348240

Reperfusion injury after cerebral ischemia: an "in vivo" study using neuro‐imaging markers

Toscana Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02348258

Toward a mitochondrial‐imbalance readjustment therapeutic approach to counteract remote degeneration after focal acute brain damage



Pagina 50 di 231



SCORE.


STRATEGICA

RF‐2011‐02346993

Interference evaluation of cancer microenvironment in the tumor‐specific immune response of pancreatic cancer patients


RF‐2011‐02352373

NOVEL AND SELECTIVE ANTI‐TUMOR STRATEGIES FOR THE TREATMENT OF GLIOMA

IDI Biomedical Oncology 1 ‐ Basic Translational 12Oncology

RF‐2011‐02346938

ASIC1: a Therapeutic Target for new neuroprotective pharmacological approaches for multiple sclerosis



RF‐2011‐02352096

Alcohol intake and abuse in workplaces: development of an integrated protocol based on screening questionnaire and new methods for biological sampling and analysis. Application in healthcare workers according to Italian legislation

Emilia‐Romagna Clinical Risk, Prevention and Health Behavior


RF‐2011‐02349311

Development of different technologies and alternative in vivo assays to evaluate the safety of medical devices.

IZS Lombardia e dell'Emilia Biomedical Veterinary 12,25Food safety and animal welfare

RF‐2011‐02350948

Animal and human monoamine oxidases inhibition as a new strategy against anthracyclines‐induced mitochondrial cardiotoxicity in cancer therapy

I.E.O. Clinical Oncology 2 ‐ Translational Clinical 12,5Oncology

RF‐2011‐02347554

Cardiovascular risk and genetic hypercholesterolemias: improving risk assessment to optimize treatment.

Sicilia Biomedical Genes, Genomes and Genetics 12,5Metabolism disorders and cardiovascular disease

Pagina 51 di 231



SCORE.


STRATEGICA

RF‐2011‐02349172

Genetic and epigenetic biomarkers in myasthenia gravis

Toscana Biomedical Genes, Genomes and Genetics 12,5Neurological diseases

RF‐2011‐02348483

Predicting post‐surgery complications in patients undergoing coronary artery bypass graft or major spine surgery through the assessment of perioperative cardiovascular control indexes

GALEAZZI Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02347483

Standardization of cord blood CD34+ cell count in a European multicenter trial. Impact on haematopoetic stem cell transplantation for haematological

malignancies.

Lombardia Biomedical Vascular and Hematology 12,5Oncology

RF‐2011‐02347481

Epigenetic therapy for the treatment of Parkinson's disease and improvement of exercise‐based rehabilitation

S.CAMILLO Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349924

The use of classical conditioning with a telemedicine approach for anomia rehabilitation in chronic aphasia: a clinical outcome research



RF‐2011‐02349734

Effects of mandibular stretching on arterial blood pressure in normal volunteers and in patients with arterial hypertension: a single blinded randomized study

Toscana Clinical Cardiovascular and Respiratory Sciences


Pagina 52 di 231



SCORE.


STRATEGICA

RF‐2011‐02347687

ASSESSMENT OF NEOPLASTIC CONTAMINATION IN CRYOPRESERVED OVARIAN TISSUE OF PATIENTS AFFECTED BY SARCOMAS AND HEMATOLOGICAL MALIGNANT DISEASES: SAFETY OF TISSUE

AUTOTRANSPLANTATION


RF‐2011‐02349418

Gut Bacteria (microbiOta) in HepAtic EncephaLopathy and Possible Utility of its Modulation (the GOAL study)

DE BELLIS Clinical Infectious Diseases and Microbiology


RF‐2011‐02352570

Hyperthermic intra‐peritoneal chemotherapy (HIPEC) in Ovarian cancer recurrence: a Randomized multicentric trial on Survival Evaluation[HORSE trial]

Umbria Clinical Oncology 2 ‐ Translational Clinical 12,5Oncology

RF‐2011‐02351276

IDENTIFICATION OF AN AUTOIMMUNE AETIOLOGY, AS DETERMINED BY SERUM AUTOANTIBODIES TO LGI1 AND OTHER CELL‐SURFACE MEMBRANE PROTEINS, IN TEMPORAL LOBE EPILEPSIES OF OTHERWISE UNKNOWN AETIOLOGY




RF‐2011‐02349589

INHIBITION OF DRUGGABLE GENE ABERRATIONS IN ER‐POSITIVE OR TRIPLE NEGATIVE OPERABLE BREAST CANCER. A WINDOW OF OPPORTUNITY TRIAL


Pagina 53 di 231



SCORE.


STRATEGICA

RF‐2011‐02352283

The role of epigenetic in thyroid cancer progression and resistance to radio‐iodine therapy. Focus on multiple promoter methylation of thyroid‐specific genes (TSH‐R, NIS, SLC26A4, SLC5A8), and non thyroid specific BRAF‐associated genes (TIMP3, DAPK, RAR‐B


RF‐2011‐02352589

Effects pf pre‐surgical cognitive rehbilitation on memory outcome after temporal lobe epilepsy surgery



RF‐2011‐02347578

Novel high‐troughoutput approaches for minimal residual disease (MRD) detection in mantle cell lymphoma (MCL)

Provincia autonoma Bolzano

Clinical Oncology 2 ‐ Translational Clinical 12,5Oncology

RF‐2011‐02348436

The role of breath fingerprints in differential diagnosis and treatment response of lower respiratory tract infections of bacterial origin

Sicilia Clinical Bioengineering Sciences and Technologies


RF‐2011‐02351923

miRNAs in lung tumorigenesis: expression signatures of serum circulating miRNAs in lung cancer patients and their functional analysis

SDN Biomedical Oncology 2 ‐ Translational Clinical 12,5Oncology

RF‐2011‐02349331

Lung cancer cell cultures from mediastinal node metastasis to develop target therapies.

Lazio Clinical Oncology 1 ‐ Basic Translational 12,5Oncology

RF‐2011‐02348175

Molecular mechanisms of cystic fibrosis inflammation: Identification of novel potential biomarkers and therapeutic targets.

Abruzzo Biomedical Cardiovascular and Respiratory Sciences


Pagina 54 di 231



SCORE.


STRATEGICA

RF‐2011‐02349179

Prognostic and Predictive microRNA Biomarkers in Sarcoma

C.R.O. AVIANO Biomedical Oncology 2 ‐ Translational Clinical 12,5Oncology

RF‐2011‐02348219

Soluble urokinase plasminogen activator receptor sustains immune activation in HIV+ individuals.


RF‐2011‐02348273

Evaluation of the effect of testosterone replacement therapy (TRT) on prostatic gland in hypogonadal patients affected by benign prostatic hyperplasia (BPH) and metabolic syndrome (MetS)



RF‐2011‐02350510

NEXT GENERATION SEQUENCING OF GLIOBLASTOMA IMMUNOEDITING AFTER DENDRITIC CELL IMMUNOTHERAPY

CARLO BESTA Biomedical Oncology 2 ‐ Translational Clinical 12,5The new biotechnologies

RF‐2011‐02348281

Synthesis and characterization of peptide‐peptidomimetics with antagonistic activity against thrombopoietin (TPO) for the treatment of severe sepsis and septic shock: pre‐clinical studies.

Piemonte Biomedical Infectious Diseases and Microbiology


RF‐2011‐02350131

PINOCCHIO: computer‐aided Planning and monItoriNg biological bOne reConstructions in CHIldren Oncology.

RIZZOLI Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering

12,5Oncology

RF‐2011‐02351729

Psychological implications in robotic rehabilitation for sub‐acute stroke patients

Veneto Clinical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02351969

Mechanisms of fluoropyrimidine toxicities in the perspective of personalized medicine.

ARCISPEDALE‐Reggio Emilia


Pagina 55 di 231



SCORE.


STRATEGICA

RF‐2011‐02348875

A multidisciplinary approach to Early Onset Dementia



RF‐2011‐02351766

AVIAN BOTULISM IN LAZIO REGION: DEVELOPMENT OF A FIELD MODEL TO UNDERSTAND THE PATHOGENESIS OF AN EMEGERGING DISEASE

IZS Lazio e della Toscana Biomedical Veterinary 12,5Food safety and animal welfare

RF‐2011‐02351126

The Impact of Prenatal Immune Deregulations on Synaptopathies: the case of maternal cytomegalovirus infection.

HUMANITAS Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02347284

unraveling the pathogenesis of autoinflammatory syndromes: from improved molecular diagnosis to the identification of novel therapeutic targets

BURLO GAROFALO Clinical Immunology 12,5Infection and immunity

RF‐2011‐02350140

Endothelial cell alterations in metabolic syndrome, obesity and diabetes: Gender, molecular and cellular mechanisms in prevention of cardiovascular risk.

MULTIMEDICA Biomedical Vascular and Hematology 12,5Metabolism disorders and cardiovascular disease

RF‐2011‐02349169

The emerging role of microRNAs in autism spectrum disorders

OASI MARIA S.S. Biomedical Genes, Genomes and Genetics 12,5Neurological diseases

RF‐2011‐02349149

Therapeutic drug monitoring protocols for dose personalization of antibacterial agents

administered to patients with severeGram‐positive infections



Pagina 56 di 231



SCORE.


STRATEGICA

RF‐2011‐02352247

A COMBINATION THERAPY COMPRISING A 'MEGADOSE' OF T CELL DEPLETED HEMATOPOIETIC STEM CELL TRANSPLANT, HIGH DOSE POST‐TRANSPLANT CYCLOPHOPHAMIDE AND A REDUCED INTENSITY CONDITIONING FOR A STABLE AND LONG TERM ENGRAFTMENT

Emilia‐Romagna Clinical Immunology 12,5Infection and immunity

RF‐2011‐02349996

Framework for Genomic Analysis and Molecular Epidemiology in foodborne bacterial pathogens (acr.: GAME‐food)

IZS Abruzzo e del Molise Biomedical Veterinary 12,5Food safety and animal welfare

RF‐2011‐02348533

Calcium‐sensing receptor as a predictive marker in hypertensive patients

SAN RAFFAELE Milano Clinical Vascular and Hematology 12,5Metabolism disorders and cardiovascular disease

RF‐2011‐02351076

Non‐coding RNAs as prognostic markers for treatment personalization of cutaneous melanoma

Veneto Biomedical Oncology 2 ‐ Translational Clinical 12,5Oncology

RF‐2011‐02347858

OVARIAN CANCER STEM CELLS: PHENOTYPIC, GENOTYPIC AND METABOLIC CHARACTERIZATION OF A SUITABLE TARGET FOR LOCO‐REGIONAL THERAPIES

I. O. V. Biomedical Oncology 1 ‐ Basic Translational 12,5Oncology

RF‐2011‐02350531

Circulating Microvesicles: a Novel Biological Marker in Crohn's Disease

Lazio Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02350363

Manipulation of the extra‐uterine environment through infant massage in preterm infants: effects on brain structure and function (a RCT)

STELLA MARIS Clinical Brain Disorders and Clinical Neuroscience


Pagina 57 di 231



SCORE.


STRATEGICA

RF‐2011‐02347199

Molecular understanding of E3 ligases involved in signaling and cancer

I.E.O. Biomedical Biological Chemistry and Macromolecular Biophysics

12,5Oncology

RF‐2011‐02351078

The use of nanoparticles in food technology: silver nanoparticles behaviour in complex food matrices and antibacterial resistance implications

IZS Venezie Biomedical Veterinary 12,5Food safety and animal welfare

RF‐2011‐02347563

ENGINEERED EXOSOMES FOR A NEW GENERATION OF ANTI‐HCV VACCINES

ISS Biomedical Immunology 12,75Infection and immunity

RF‐2011‐02349823

A susceptibility marker for Amyotrophic Lateral Sclerosis: genetic and functional analysis of polymorphisms of P2RX7 gene coding for purinergic P2X7 receptor for extracellular ATP, in a cohort of ALS patients.



RF‐2011‐02351902

Alloimmunity and infection: insight into pathogen‐driven alloreactivity to develop preventive strategies for late kidney graft failure

GASLINI Clinical Digestive, Kidney and Urological Systems


RF‐2011‐02350279

Electro‐clinical features, brain networks, and gene expression in Ring20 epilepsy syndrome

Lombardia Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02350593

Identification of inducers of skin wound repair for the treatment of non‐healing ulcers in diabetic patients

IDI Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02350859

Microglia‐based device as a biosensor for Amyotrophic Lateral Sclerosis pathogenesis



Pagina 58 di 231



SCORE.


STRATEGICA

RF‐2011‐02351046

The purinergic P2X7 receptor on human cardiac fibroblast: a new therapeutic target to control cardiac remodelling in chronic heart failure?



RF‐2011‐02349837

Role of brain/cognitive reserves on neurodegenerative pathology



RF‐2011‐02351132

Prevention of antibody‐mediated chronic allograft injury in a prospective longitudinal study in renal transplant patients

Veneto Biomedical Immunology 13The new biotechnologies

RF‐2011‐02351061

Pediatric Cardiomyopathy: new genetic diagnostic approach by next generation sequencing (NGS) and its relation to therapeutic efficacy

SDN Biomedical Genes, Genomes and Genetics 13Metabolism disorders and cardiovascular disease

RF‐2011‐02349912

A preclinical translational study for pharmacological inhibition of G protein Receptor Kinase 2 for the treatment of cardiac dysfunction: A metabolic approach.

Campania Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02350078

GALACTOSYLATED PRODRUG OF KETOROLAC WITH BETTER PHARMACOKINETIC PROPERTIES AND REDUCED TOXICITY

Campania Clinical Interdisciplinary Molecular Sciences and Training


RF‐2011‐02351009

A multidisciplinary investigation for the improvement of aortic endografting: from biomedical engineering concepts to clinical implementation.

SAN DONATO Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering


Pagina 59 di 231



SCORE.


STRATEGICA

RF‐2011‐02350700

The Lectin pathway as a therapeutic target in stroke



RF‐2011‐02349897

Viral microRNAs: a secret weapon for host gene expression alteration in B‐cell lymphomas


RF‐2011‐02348224

Standard Operating Procedures for MR‐based Cortical Thickness Estimation



RF‐2011‐02351552

A genome‐based and functional approach to improve the diagnosis and define the molecular basis of syndromic and non‐syndromic intellectual disability

Piemonte Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02351570

Role of intestinal microbiota in the occurrence of systemic septic complications in patients with post‐traumatic spinal cord and cerebral injury.

Emilia‐Romagna Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02351613

Aphasia. Theory for Therapy. S.CAMILLO Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349091

Serum myostatin and type 2 diabetes: correlation with degree of metabolic control

SDN Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351723

Advanced and innovative procedures for diagnosis and management of patients affected by Limb Girdle Muscle Dystrophies (LMGD) and other related myopathies.

NEUROLESI Clinical Musculoskeletal, Oral and Skin Sciences


Pagina 60 di 231



SCORE.


STRATEGICA

RF‐2011‐02348858

Effectiveness of a Communication Skills Training program for oncology clinicians on patient Health‐Related Quality of Life: a stepped‐wedge, cluster randomized controlled trial

Lombardia Clinical Risk, Prevention and Health Behavior

13Oncology

RF‐2011‐02348699

A packaging RNA nanotherapeutic approach to arrest nigrostriatal dopaminergic neuronal cell death in experimental Parkinson's disease



RF‐2011‐02348681

Autologous transplantation of SPIO‐labeled bone marrow stem cells in Critical Limb Ischemia (CLI): a preclinical study.

Liguria Biomedical Vascular and Hematology 13Metabolism disorders and cardiovascular disease

RF‐2011‐02348661

Cotransplantation of pancreatic islets and engineered, third‐party, human umbilical cord mesenchymal stem cells as a novel approach to improve graft survival and immune‐tolerance in type 1 diabetes patients

Toscana Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02348649

Peptides from lactoferrin as new therapeutic agents against Influenza virus infection



RF‐2011‐02350839

Telemedicine network for diagnosis and care of congenital heart malformations



RF‐2011‐02348532

Dipeptidyl peptidase IV inhibitors and the complex P2X7 receptor‐inflammasome: in vitro and in vivo studies.

Toscana Biomedical Risk, Prevention and Health Behavior


Pagina 61 di 231



SCORE.


STRATEGICA

RF‐2011‐02351549

Acute coronary syndrome and long term outcome: the role of nitric oxide synthesis in red blood cells

MONZINO Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02348318

Analysis of KIR genotype/phenotype and HLA supratype on NK and CD8+ T cell subpopulations in elite controller, long term non‐progressor and HIV‐1‐cronically infected subjects

GASLINI Biomedical AIDS and Related Research 13Infection and immunity

RF‐2011‐02348439

PREVENTION AND DIAGNOSIS OF FETAL ALCOHOL SYNDROME (FAS) AND FETAL ALCOHOL SPECTRUM

DISORDER(FASD)

Lazio Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02348223

Combinatorial treatments to target cancer stem cells and elicit DNA damage in triple negative breast cancer


RF‐2011‐02348141

Cortical myoclonus: implementation of innovative quantitative diagnostic tests and a new therapeutic strategy based on repetitive transcranial magnetic stimulation.



RF‐2011‐02352176

A biopathological investigation of Nodular Lymphocyte Predominant Hodgkin Lymphoma in pediatric and adolescents patients.

C.R.O. AVIANO Biomedical Oncology 2 ‐ Translational Clinical 13Oncology

RF‐2011‐02347764

Interferome: renaissance of the innate immune system in understanding dysregulated genes and networks in multiple sclerosis.



Pagina 62 di 231



SCORE.


STRATEGICA

RF‐2011‐02347584

Metal on metal hip prosthesis: Cobalt‐induced neurotoxicity

RIZZOLI Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02352325

Development and validation of a multiplex real‐time PCR assay for the identification and discrimination of virulent Listeria monocytogenes strains in food


RF‐2011‐02352418

Characterization of the interactions occurring inside the EGFR axis macromolecular complexes expressed in pancreatic ductal adenocarcinoma

Lazio Clinical Oncology 2 ‐ Translational Clinical 13Oncology

RF‐2011‐02352423

Advanced ovarian cancer as an immunologic, endocrine and metabolic disorder. Translational research for the development of a targeted approach of advanced ovarian cancer‐related symptoms.

Sardegna Biomedical Oncology 2 ‐ Translational Clinical 13Oncology

RF‐2011‐02352456

Early use of extracorporeal membrane oxygenation in Cardiogenic Shock (ECMICS)

Lombardia Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02347258

Assessment of transplant benefit of downstaging strategies in patients with hepatocellular carcinoma exceeding Milan Criteria: a randomized study

IST.TUMORI MILANO Clinical Oncology 2 ‐ Translational Clinical 13Oncology

RF‐2011‐02347211

NOVEL TOOLS TO STUDY AND INHIBIT MALARIA GAMETOCYTE SEQUESTRATION IN HUMAN BONE MARROW



Pagina 63 di 231



SCORE.


STRATEGICA

RF‐2011‐02346965

Metastasis at the onset: to inhibit cell cannibalism in order to hinder tumor spreading


RF‐2011‐02346855

Branched peptides as cancer theranostics Toscana Biomedical Oncology 2 ‐ Translational Clinical 13Oncology

RF‐2011‐02351931

Modulation of miRNA lung cancer risk biomarkers by low‐dose aspirin in former smokers

Liguria Clinical Oncology 2 ‐ Translational Clinical 13Oncology

RF‐2011‐02349531

Therapeutic potential and safety assessment of gene‐corrected Neural Stem/Progenitor Cells (NSPC) derived from patient‐specific induced Pluripotent Stem Cells (iPSC) in murine models of Lysosomal Storage Diseases (LSD).

SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 13Neurological diseases

RF‐2011‐02349752

Laparoscopic sleeve gastrectomy versus conventional medical therapy in patients with newly diagnosed type 2 diabetes and Body Mass Index 30‐34.9 Kg/m2: a randomized clinical trial

Umbria Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351523

Proof‐of‐principle investigation of NAMPT inhibitors in cancer and inflammatory states


RF‐2011‐02349661

Markers of refractoriness in Gilles de la Tourette syndrome: pharmachological therapies and deep brain stimulation.

GALEAZZI Biomedical Brain Disorders and Clinical Neuroscience


Pagina 64 di 231



SCORE.


STRATEGICA

RF‐2011‐02349635

Non Alcoholic Fatty Liver Disease (NAFLD) , vitamin D and cardiometabolic risk: a proof of concept study

Lombardia Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02349283

Pathophysiology of frontal cortical impairments in phenylketonuria: a translational investigation.



RF‐2011‐02349495

Global Rare Tumor Networking and new staging/prognostic concepts in Thymic Epithelial Tumors and in Non Small Cell Lung Carcinomas metastatic to the Mediastinum: an integrated

clinicopathological and molecular study

REGINA ELENA Clinical Oncology 2 ‐ Translational Clinical 13Oncology

RF‐2011‐02348744

A combined therapeutic approach to Spino‐Bulbar Muscle Atrophy (SBMA): from cellular models to clinical studies



RF‐2011‐02348459

A needs‐based approach to forecast future medical specialists' requirement for the Emilia‐Romagna Regional (ERR) NHS



RF‐2011‐02349801

The possible role of transforming growth factor beta1 and vitamin D in regulating disease activity and brain atrophy in patients with Multiple Sclerosis.



RF‐2011‐02347423

Dendritic cell engineering with IRF‐1 and IRF‐8 for new immunotherapy interventions


Pagina 65 di 231



SCORE.


STRATEGICA

RF‐2011‐02350532

Occurrence of Ostreopsis genus blooms in Tyrrhenian sea : tools to prevent human intoxication due to palytoxins contaminated seafood.


RF‐2011‐02352345

Discovery of new biomarkers predictive of outcome in comatose patients resuscitated from cardiac arrest




RF‐2011‐02348185

Human and swine influenza viruses: reassortment and zoonotic risks


RF‐2011‐02352495

Molecular, Pharmacogenomic and Metabolic factors associated with Recurrence in a Randomized Trial of adjuvant therapy with Aromatase Inhibitors

PASCALE Biomedical Oncology 2 ‐ Translational Clinical 13,5Oncology

RF‐2011‐02352578

Detection of Oxidative Base‐Specific Lesions in the Exon 1 of the K‐RAS and Other Cancer Related Genes of Patients with Newly Diagnosed Colorectal Adenocarcinoma and Colorectal Polyps

Toscana Biomedical Population Sciences and Epidemiology

13,5Oncology

RF‐2011‐02350449

Dissection of the effects of mesenchymal stem cells on glial cells involved in neurogenesis




RF‐2011‐02348265

Novel approaches to understand HIV‐1 nucleotide diversity affecting viral evolution, drug‐resistance development, and related clinical implications

SPALLANZANI Biomedical AIDS and Related Research 13,5Infection and immunity

Pagina 66 di 231



SCORE.


STRATEGICA

RF‐2011‐02349816

Development of anti‐PD‐1 single chain antibodies with finely balanced affinity for effective immunotherapy against HIV


RF‐2011‐02347271

Role of basophils derived interleukin‐4 in driving thymic stromal lymphopoietin dependent pro‐tumor Th2 inflammation in pancreatic cancer


RF‐2011‐02347188

Cellular and molecular mechanisms underlying the dyskinetic effects of L‐DOPA versus Dopamine D2‐D3 agonists



RF‐2011‐02348323

Novel clinical and pathogenic insight in the interplay between genotype 1 HCV infection and type 2 diabetes.



RF‐2011‐02350665

A pathology for the MET oncogene: 'cancers of unknown primary origin' (CUPs)

Piemonte Biomedical Oncology 1 ‐ Basic Translational 13,5Oncology

RF‐2011‐02351314

A long term control of biofilms and Legionella contamination of dental unit waterline to prevent patients and occupational infections using a natural terpinen‐4 ol.

ISS Biomedical Risk, Prevention and Health Behavior


RF‐2011‐02349794

SECURITY STANDARDIZATION AND ADAPTING OF MODERN RADIOTHERAPY THROUGH IN‐VIVO DOSIMETRY

Lazio Clinical Oncology 2 ‐ Translational Clinical 13,5Oncology

Pagina 67 di 231



SCORE.


STRATEGICA

RF‐2011‐02351351

Identification of new causative mechanisms underling Brugada Syndrome and advanced functional analysis in patient‐specific

induced pluripotent stem‐cell models.

SAN RAFFAELE Milano Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02350645

Cell‐on‐Chip technology as an alternative to mouse model to evaluate allergenic potential of airborne substances and of preparations for allergen‐specific immunotherapy.


RF‐2011‐02352152

Analysis of late radiation damages in terms of neurocognitive outcome after focal radiotherapy for childhood malignant brain tumors by a correlation of absorbed dose levels and magnetic resonance diffusion tensor imaging (DTI) values

IST.TUMORI MILANO Clinical Oncology 2 ‐ Translational Clinical 13,5Oncology

RF‐2011‐02348079

Ostreopsis cf. ovata in Mediterranean fish and shellfish products: new methods for the early identification of algal toxins, mechanism of action and human risk assessment.


RF‐2011‐02347989

Towards an optimization of epigenetic therapy of cancer


RF‐2011‐02349866

Unveiling the role of c‐MET and ALK gene alterations as druggable targets in pulmonary sarcomatoid carcinoma, a therapeutically challenging subtype of lung cancer


Pagina 68 di 231



SCORE.


STRATEGICA

RF‐2011‐02347980

An integrated genomic and immunomic analysis of colon cancer to identify unique tumor antigens and parameters of underlying immune response related to disease outcome


RF‐2011‐02347782

Randomized pilot phase II study of Lenalidomide as adjuvant therapy for prevention in Hepatocellular carcinoma (HCC) recurrence after radiofrequency thermal ablation (RFA): molecular and immunological prognostic biomarkers

Emilia‐Romagna Biomedical Oncology 2 ‐ Translational Clinical 13,5Oncology

RF‐2011‐02352261

Glioblastoma Cancer Stem Cells: a tool for identification of new diagnostic/prognostic markers and development of innovative therapeutics



RF‐2011‐02347669

Characterization of cystic fibrosis airway microbiome in patients showing a severe decline in lung function and not responding to antimicrobial therapy: a multicentre study




RF‐2011‐02350607

Awareness and competence in mild to moderate Alzheimer's disease patients: clinical and forensic implications.

Veneto Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02351546

Understanding the interaction between inflammatory factors profile in stroke patients to design a tailored therapeutic approach



Pagina 69 di 231



SCORE.


STRATEGICA

RF‐2011‐02346935

Analysis of hepatitis C virus heterogeneity in direct‐acting antivirals (DAAs) targeted

region (non‐structural region 3) during anti‐HCV treatment: new implications for

treatment strategy.

SAN RAFFAELE Milano Clinical Infectious Diseases and Microbiology


RF‐2011‐02352796

Computer Assisted Evaluation of Fracture Risk in Tumor Spine Lesions

RIZZOLI Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering

13,5Oncology

RF‐2011‐02349107

Role of miR‐155 in FLT3 ITD in mutated acute myeloid leukemia: studies of network, signalling and silencing

Sicilia Biomedical Oncology 1 ‐ Basic Translational 13,5Oncology

RF‐2011‐02352784

Novel Electrochemical Cancer Diagnostics I.E.O. Biomedical Bioengineering Sciences and Technologies

13,5Oncology

RF‐2011‐02348907

A novel truncated variant of eNOS as a major risk factor for type 2 diabetes



RF‐2011‐02351202

Inhibition of endocannabinoids‐hydrolyzing enzymes as a new therapeutic target for migraine treatment: studies in animal models and preliminary evaluation in humans



RF‐2011‐02348890

Livestock‐associated methicillin‐resistant Staphylococcus aureus (LA‐MRSA) as cause of human infection and colonization in an Italian Region with high density of pig farming

ISS Clinical Infectious Diseases and Microbiology


Pagina 70 di 231



SCORE.


STRATEGICA

RF‐2011‐02346923

Exploiting the p53‐p66Shc signaling pathway to identify new molecular markers

for the prevention of cancerand age‐ related diseases

I.E.O. Biomedical Biology of Development and Aging 13,5Oncology

RF‐2011‐02346774

HLA‐G expression and DC‐10 as new risk factors for HHV6 reactivation after allo‐HSCT.


RF‐2011‐02351066

THE MENTAL HEALTH OF UNIVERSITY STUDENTS: AN ITALIAN WEB‐BASED SURVEY

FATEBENEFRATELLI Clinical Risk, Prevention and Health Behavior


RF‐2011‐02348750

Molecular characterization of human atherosclerotic plaques: role of Calcium‐Calmodulin dependent kinases and of their activating receptors in vascular wall and infiltrating inflammatory cells.



RF‐2011‐02348715

In vitro and in vivo testing of novel therapeutic strategies for lysosomal leukodystrophies: aptamer‐mediated delivery of functional enzymes and gene silencing approaches

GASLINI Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02351777

Development of a dedicated ICP‐MS based miR‐sassay to quantify circulating microRNA for the improvement of acute myocardial infarction diagnosis

I.N.R.C.A. Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02350230

Predictive markers of cardiovascular diseases: role of miRNAs in endothelial damage.


Biomedical Vascular and Hematology 13,5Metabolism disorders and cardiovascular disease

Pagina 71 di 231



SCORE.


STRATEGICA

RF‐2011‐02351093

Intestinal microbiota and chronic inflammatory disease in children.



RF‐2011‐02352719

A NOVEL ¿EX VIVO¿ SYSTEM FOR MONITORING THROMBUS FORMATION UNDER FLOW BASED ON ELECTRICAL IMPEDANCE TOMOGRAPHY

C.R.O. AVIANO Biomedical Vascular and Hematology 13,5The new biotechnologies

RF‐2011‐02346940

An in vitro ad in vivo imaging approach to myelin dysfunction and reconstruction after stroke: role of GPR17, a new player in oligodendrocyte specification

MONZINO Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349174

New Therapeutic Approaches for Tuberculosis



RF‐2011‐02349812

A randomized intervention trial in breast cancer patients to evaluate a protocol aimed to obtain dietary and physical activity sustainable and permanent modifications in breast cancer patients and its effects on weight and metabolic aspects.


RF‐2011‐02348475

IMAGE‐BASED PREDICTIVE MODELLING OF TUMOUR RESPONSE AND NOMAL TISSUE COMPLICATONS IN THE RADIOTHERAPY OF PELVIC MALIGNACIES


RF‐2011‐02351102

Muscle toxicity of proteasome inhibitor bortezomib


Pagina 72 di 231



SCORE.


STRATEGICA

RF‐2011‐02348486

Prostaglandin D2 synthase a novel pathway modulating PNS myelination



RF‐2011‐02348733

Tailoring engineered micro‐nanocarriers properties to finely modulate immune responses: the allergy immunotherapy proof of concept


RF‐2011‐02348487

DNA damage response and metabolic alterations of obesity



RF‐2011‐02350366

Genomics, epigenomics and transcriptomic investigation of defective peripheral tolerance in IPEX‐like patients

SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 13,75Infection and immunity

RF‐2011‐02352079

IMPACT OF VIDEOTHORACOSCOPIC, ROBOTIC AND OPEN LOBECTOMY ON QUALITY OF LIFE AND IMMUNE RESPONSE IN LUNG CANCER PATIENTS


RF‐2011‐02349313

Exploring the functions of the immune system in chronic fatigue syndrome (CFS) by means of silent viral infections and cytokine pathway evaluations and proteomic approach

Toscana Clinical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02347031

Development of a wearable system for the integrated assessment of seismocardiogram and other vital signs out of the laboratory setting.

DON GNOCCHI Biomedical Bioengineering Sciences and Technologies


Pagina 73 di 231



SCORE.


STRATEGICA

RF‐2011‐02349865

Development of immunoassays for the evaluation of human exposure to Aedes mosquitoes: a novel tool for the assessment of efficacy of vector control strategies and estimation of arboviral disease risk.



RF‐2011‐02346977

Slow potentials due to glial dysfunction as biomarkers of the seizure‐onset zone in surgically‐remediable focal epilepsies



RF‐2011‐02351853

Tailored screening for colorectal cancer. Modulating screening interventions on individual risk profile

Piemonte Clinical Risk, Prevention and Health Behavior

13,75Oncology

RF‐2011‐02350537

Identification of environmental and genetic risk factors in Autism Spectrum Disorders



RF‐2011‐02349854

An effective vaccine to prevent mucosal HIV infection based on an HIV‐1 env DNA prime ‐ gp140 trimeric protein boost immunization regimen in the presence of CCL28: proof of efficacy in cynomolgous macaques.

SAN RAFFAELE Milano Biomedical AIDS and Related Research 14Infection and immunity

RF‐2011‐02347508

Therapy de‐escalation in Inflammatory Bowel Disease ‐ Identification of biomarkers to assess prognostic factors in patients with mucosal healing



RF‐2011‐02346792

Governance of diabetes management in non‐specialistic hospital settings



Pagina 74 di 231



SCORE.


STRATEGICA

RF‐2011‐02347432

Safety and technology assessment of Ultra High Field Magnetic Resonance 7 Tesla System for children applications

STELLA MARIS Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02350805

A National Electronic Library for Oncology (aNELO)

REGINA ELENA Biomedical Healthcare Delivery and Methodologies

14Oncology

RF‐2011‐02349805

Preclinical characterization of a potent antimicrobial peptide for the development of a new drug for Cystic Fibrosis



RF‐2011‐02346915

Multifunctional "hybrid" drugs for targeting skeletal metastases

RIZZOLI Biomedical Oncology 2 ‐ Translational Clinical 14Oncology

RF‐2011‐02349765

IDENTIFICATION OF NOVEL MOLECULAR MECHANISMS IN THE ETHIOPATHOGENESIS OF OVARIAN CANCER

Abruzzo Biomedical Oncology 1 ‐ Basic Translational 14Oncology

RF‐2011‐02350686

Investigating epigenetic patterns induced by different diets and food for cancer‐‐preventive health enhancement

I.E.O. Biomedical Genes, Genomes and Genetics 14Food safety and animal welfare

RF‐2011‐02346973

Modulating TACE secretase activity and Neuregulin 1 type III signaling to treat inherited hypermyelinating neuropathies



RF‐2011‐02350795

Immuno‐predictors of cardiovascular risk in patients with psoriatic arthritis


Clinical Immunology 14Metabolism disorders and cardiovascular disease

Pagina 75 di 231



SCORE.


STRATEGICA

RF‐2011‐02348887

Role of local immune response in the development of ano‐genital HPV related invasive diseases

Lombardia Clinical Immunology 14Infection and immunity

RF‐2011‐02348454

Fosl2 as a p53 antagonist in cancer development and progression

C.R.O. AVIANO Biomedical Oncology 1 ‐ Basic Translational 14Oncology

RF‐2011‐02348472

Circulating nucleic acids in colorectal cancer: new non‐invasive tools for patient risk assessment and early diagnosis in high risk individuals


RF‐2011‐02349625

The Hereditary Diffuse Gastric Cancer syndrome: from susceptibility genes to clinical management

I.E.O. Biomedical Genes, Genomes and Genetics 14Oncology

RF‐2011‐02349925

Composition and dynamics of cholesterol‐rich membrane microdomains in malaria parasite infection ‐ identification of potential targets for novel intervention strategies



RF‐2011‐02349525

Conventional multi‐port laparoscopic colectomy versus single‐incision colectomy for cancer: comparison of short‐ and long‐term results by a randomized study

Toscana Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering

14Oncology

RF‐2011‐02348698

Dissection of Pertussis Toxin B‐oligomer (PTB) in adjuvant and anti‐viral components: human and mouse preclinical platforms to the identification of dimers/monomers/minimal domains to be developed as intracellular pathogen adjuvant and anti‐viral molecul


Pagina 76 di 231



SCORE.


STRATEGICA

RF‐2011‐02348208

Do anti‐LRP4 antibodies play a pathological significance in amyotrophic lateral sclerosis?

CARLO BESTA Biomedical Immunology 14Neurological diseases

RF‐2011‐02349462

ULTRAsound in ischemic Stroke (ULTRAS) study


Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02348351

Modulation by IL‐1beta of GABAA and Glutamate Receptors function in human and experimental epilepsy: a novel therapeutic approach for intractable epilepsies.




RF‐2011‐02350154

A minimal residual disease‐driven approach to the patient affected by follicular

lymphoma receiving R‐CHOP


RF‐2011‐02348916

Neuroactive steroids in Multiple Sclerosis, correlation with immunity and neurodegeneration



RF‐2011‐02348978

Role of the mitogen‐activated protein kinase ERK5 in the development of hepatocellular carcinoma associated with chronic liver injury

Toscana Biomedical Digestive, Kidney and Urological Systems

14Oncology

RF‐2011‐02350106

Clinical validation of an optimized MRI protocol for early diagnosis and monitoring of progressive multifocal leukoencephalopathy



RF‐2011‐02349203

Exploring the mechanisms of the cardiovascular effects of urban air particulate matter in susceptible individuals.



Pagina 77 di 231



SCORE.


STRATEGICA

RF‐2011‐02349168

NEW HYBRID POLYMERIC SCAFFOLD FOR OSTEOCHONDRAL ENGINEERED TREATMENT

RIZZOLI Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02350186

Development of cultured red blood cells with rare phenotypes for diagnostic and clinical use

ISS Biomedical Vascular and Hematology 14The new biotechnologies

RF‐2011‐02348214

HUMANS AND WILDLIFE: ZOOS IN BETWEEN. ARE ZOOS A THREAT OR BIOSENTINELS FOR INFECTIOUS DISEASES?


Biomedical Veterinary 14Food safety and animal welfare

RF‐2011‐02349858

Investigations on the genetic predisposition to the copper metabolism dysfunction associated with Alzheimer's disease


Biomedical Genes, Genomes and Genetics 14Neurological diseases

RF‐2011‐02347640

Nef protein of HIV‐1 contributes in increasing susceptibility to malaria and opportunistic infections through downregulation of class B scavenger receptor CD36 expression


RF‐2011‐02347776

Inflammatory environment in patients with peritoneal carcinomatosis from gastrointestinal malignancies undergoing cytoreductive surgery and HIPEC: research of systemic and peritoneal involved factors and development of a murine model

SAN RAFFAELE Milano Clinical Oncology 2 ‐ Translational Clinical 14Oncology

RF‐2011‐02350548

Estrogenic endocrine disruptors impact on autoimmunity onset and progression: the paradigm of Systemic Lupus Erythematosus

ISS Clinical Immunology 14Infection and immunity

Pagina 78 di 231



SCORE.


STRATEGICA

RF‐2011‐02347810

Advanced diagnosis and therapies for migraine caused by K+ channel dysfunction

MONDINO Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02347941

SOCIAL INTERACTION AND RIGHT BRAIN DAMAGE IN STROKE PATIENTS

AUXOLOGICO Clinical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02348502

Influence of diet on composition of faecal microbiota and metabolites, metabolomics, in two informative cohorts: African children eating a Western diet. Implications on obesity onset and its control (MICROBESITY)

DE BELLIS Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02348437

alpha7‐nAChR status and response to donepezil in Alzheimer's disease patients




RF‐2011‐02348362

Study of the involvement of KDEL receptors in inflammatory bowel disease

Abruzzo Biomedical Cell Biology 14Infection and immunity

RF‐2011‐02348216

A translational approach to restrain local recurrence in early breast cancer patients

C.R.O. AVIANO Biomedical Oncology 1 ‐ Basic Translational 14Oncology

RF‐2011‐02350470

New role of S‐nitrosoglutathione reductase (GSNOR) in aging and Alzheimer disease: How epigenetics regulates S‐nitrosylation‐based signaling and nitrosative stress.


Biomedical Biology of Development and Aging 14Neurological diseases

RF‐2011‐02349707

GENETICS OF ENDOTHELIAL FUNCTION IN UNDERSTANDING THE PATHOGENESIS OF LACUNAR STROKE AND SMALL VESSEL DISEASE



Pagina 79 di 231



SCORE.


STRATEGICA

RF‐2011‐02349914

Association between long‐term exposure to air pollution and neurological and metabolic impairment in adults of two large Italian longitudinal studies

Piemonte Clinical Population Sciences and Epidemiology


RF‐2011‐02348274

Research of new neuroimaging biomarkers to early identify different epilepsy phenotypes in patients with Tuberous Sclerosis Complex (TSC).




RF‐2011‐02349662

Role of Periostin in prostate and breast carcinogenesis. Integrated approaches for the identification of novel prognostic and therapeutic targets.


Biomedical Oncology 2 ‐ Translational Clinical 14Oncology

RF‐2011‐02347577

Otoacoustic emissions as biomarkers of possible synergistic interaction in inducing hearing damage: an experimental study

INAIL Biomedical Population Sciences and Epidemiology


RF‐2011‐02348128

Molecular profiling of laser‐microdissected prostate tissue from prostate cancer patients and not‐yet patients

Abruzzo Biomedical Oncology 1 ‐ Basic Translational 14Oncology

RF‐2011‐02350961

Integrated panel of biomarkers to evaluate seafood exposure to emerging contaminants along the Ligurian coasts and associated human health risks (IBIDEM)



RF‐2011‐02351343

Tissue proteome and secretome of benign and malignant parathyroid tumors: identification of molecular and biochemical biomarkers for early diagnosis of parathyroid cancer


Pagina 80 di 231



SCORE.


STRATEGICA

RF‐2011‐02351377

Epidemiological profiles and cost patterns of cancer patients (EpiCost)

ISS Biomedical Healthcare Delivery and Methodologies

14Oncology

RF‐2011‐02351391

Prevention of haemorrhagic events by minimally invasive monitoring of anticoagulant therapy

Toscana Biomedical Vascular and Hematology 14Metabolism disorders and cardiovascular disease

RF‐2011‐02351394

The role of purinome in kidney chronic allograft dysfunction: extracellular ATP as a new possible early marker and trigger of fibrosis

Emilia‐Romagna Clinical Digestive, Kidney and Urological Systems


RF‐2011‐02352497

Analysis of Arterial Stiffness in women with Systemic Lupus Erythematosus: correlations with epidemiological, clinical and laboratory parameters, with the presence of hypovitaminosis D and evaluation of the effects of Cholecalciferol supplementation.

Toscana Clinical Immunology 14Infection and immunity

RF‐2011‐02351045

Molecular signature of the progression of hepatitis C virus (HCV) chronic infection to hepatocellular carcinoma: exosome associated microRNAs and protein profiling in experimental and clinical settings

ISS Clinical Oncology 2 ‐ Translational Clinical 14Infection and immunity

RF‐2011‐02351979

Genetic disorders of lung vascular development in children:A new, integrated

approach for early recognition and molecular diagnosis.



RF‐2011‐02352320

A biological prospective study in patients with metastatic pancreatic neuroendocrine tumors treated with everolimus


Pagina 81 di 231



SCORE.


STRATEGICA

RF‐2011‐02351438

PRECLINICAL AND CLINICAL PILOT STUDIES TO ACCESS THE SAFETY AND EFFICACY OF THE USE OF HUMAN ADIPOSE TISSUE‐DERIVED MESENCHYMAL STEM CELLS TO PROMOTE TOLERANCE INDUCTION AND LIVER REGENERATION

Sicilia Biomedical Immunology 14The new biotechnologies

RF‐2011‐02351364

Applied Helicobacter pylori immunoproteomic, molecular and 3D structural approaches in gastric diseases to better understand the process of tumorigenesis and diagnostic biomarker discovery in early stage Gastric cancer

C.R.O. AVIANO Biomedical Infectious Diseases and Microbiology


RF‐2011‐02351870

Prognostic, risk stratification potentiality and cost‐effectiveness analysis of a multi‐marker strategy in the management of children with congenital heart disease



RF‐2011‐02351486

Alternative splicing of PRK2 in Parkinson's disease

Sicilia Biomedical Genes, Genomes and Genetics 14Neurological diseases

RF‐2011‐02351524

Testing EunetHTA Core Model for national HTA reporting on relevant techonologies

AGENAS Biomedical Healthcare Delivery and Methodologies


RF‐2011‐02351488

A PHASE II STUDY OF AUTOLOGOUS BONE MARROW ‐ DERIVED STEM CELL TRANSPLANTATION FOR THE TREATMENT OF CHRONIC END STAGE LIVER DISEASE



Pagina 82 di 231



SCORE.


STRATEGICA

RF‐2011‐02350927

Study of macro‐ and micro‐vascular damage in patients chronically exposed to cigarette smoking and of the impact of this assessment on the adherence of smokers to

smoking cessation programs

Toscana Clinical Risk, Prevention and Health Behavior


RF‐2011‐02352671

FROM TISSUES TO SERUM IN CANINE MAMMARY CANCER: AN INTEGRATED CONCEPT OF MALIGNANT TUMOR PROGRESSION

IZS Umbria e delle Marche Biomedical Veterinary 14Oncology

RF‐2011‐02351491

Peptidomimetic inhibitors of aspartyi proteinases as novel therapeutics to fight

mucosal candidiasis

Umbria Biomedical AIDS and Related Research 14Infection and immunity

RF‐2011‐02350874

EFFECTS OF NUTRACEUTICAL SPIRULINA ENRICHED‐DIET DURING PREGNANCY AND LACTATION ON NEURODEVELOPMENTAL DISORDERS AND SUSCEPTIBILITY TO INFLAMMATION OF THE PROGENY

ISS Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02351726

Paracrine role of Mesenchymal Stem Cells (MSCs) for cell therapy in ALS



RF‐2011‐02351155

Mental and physical health status of workers receiving redundancy payment



RF‐2011‐02351152

Topical propranolol administration to preserve visual function in newborns with retinopathy of prematurity.

Toscana Biomedical Cell Biology 14Neurological diseases

Pagina 83 di 231



SCORE.


STRATEGICA

RF‐2011‐02351150

New insight in the prevention of knee osteoarthritis progression: correlation between joint biomechanics and molecular cartilage homeostasis



RF‐2011‐02352255

Developmental Coordination Disorder in school‐age children born very preterm: validation of a screening tool and relationship with ante‐ and peri‐natal events.


Clinical Biobehavioral and Behavioral Processes


RF‐2011‐02351125

Multifactorial study, with metabolomic profiling and circulating tumor cell characterization, of microscopic residual disease and its evolution after surgery for early breast cancer

IRST Meldola Biomedical Oncology 2 ‐ Translational Clinical 14Oncology

RF‐2011‐02349813

DEVELOPMENT OF A FULL WIRELESS POLYGRAPHIC DEVICE FOR DIAGNOSIS OF SLEEP DISORDERS AND REMOTELY ATTENDED HOME MONITORING

AUXOLOGICO Clinical Emerging Technologies and Training in Neurosciences


RF‐2011‐02348463

Can epilepsy affect the structure of the brain? Role of neurons and glia and effect of

therapy in a model of epileptogenicbrain malformation



RF‐2011‐02352272

Longitudinal assessment of chemotherapy‐induced impairment of cognitive function and its correlation with structural changes in the cerebral white matter of patients with non‐small cell lung cancer (NSCLC).



Pagina 84 di 231



SCORE.


STRATEGICA

RF‐2011‐02352311

Searching for genetic profiles associated with IgE variability in health care workers and bakers exposed to occupational allergens

Veneto Biomedical Risk, Prevention and Health Behavior


RF‐2011‐02349426

Preclinical study in mouse models to evaluate the use of the chemokine Cxcl3 in the therapy of medulloblastoma

SANTA LUCIA Biomedical Oncology 1 ‐ Basic Translational 14,25Oncology

RF‐2011‐02351439

STUDY ON THE ANTIDEPRESSANT ACTIVITY OF FINGOLIMOD IN EXPERIMENTAL ANIMAL MODELS AND PATIENTS WITH MULTIPLE SCLEROSIS



RF‐2011‐02347800

Novel molecular and cellular pathophysiological mechanisms of diabetic vascular disease

Abruzzo Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02347219

Heart remodelling in Chronic Obstructive Pulmonary Disease: diagnostic and therapeutic implications.

Emilia‐Romagna Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02347204

GENETIC PREVENTION OF LYMPHOMA DEVELOPMENT IN p53 KNOCKOUT MICE REVEALS A NOVEL MOUSE MODEL OF OSTEOSARCOMA AND HEMANGIOSARCOMA. EARLY MOLECULAR AND IMMUNOLOGICAL MECHANISMS INVOLVED IN TUMOR ONSET AND MALIGNANCY AS TARGET OF INNOVATIVES THERAPIES.

RIZZOLI Biomedical Oncology 1 ‐ Basic Translational 14,5Oncology

Pagina 85 di 231



SCORE.


STRATEGICA

RF‐2011‐02351890

Prevention interventions for promoting the health of men who have sex with men (MSM) in Palermo area.

Sicilia Clinical Infectious Diseases and Microbiology


RF‐2011‐02348554

Molecular and Clinical study of next generation in Autism‐Epilepsy Phenotype: Focus on Astrocyte‐Neuron interaction.

STELLA MARIS Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02348556

A novel approach to diagnosis, allocation and treatment of HCC

SAN MATTEO Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering

14,5Oncology

RF‐2011‐02349276

Characterization of the mitochondrial oxidative defect in Spinal Muscular Atrophy. Investigation of the molecular pathways leading to mitochondrial dysfunction and their relation to Spinal Muscular Atrophy pathogenesis.



RF‐2011‐02351156

Serum miRNAs as circulating biomarkers for the early diagnosis of ovarian cancer


RF‐2011‐02349941

Investigation of mechanism of tumor development and new systemic drug treatment strategies to tackle the rising burden of hepatocellular carcinoma complicating Non Alcoholic Fatty Liver Disease.

Emilia‐Romagna Biomedical Oncology 2 ‐ Translational Clinical 14,5Oncology

RF‐2011‐02351850

Genotype‐phenotype correlation in schizophrenia: role of rare variants



Pagina 86 di 231



SCORE.


STRATEGICA

RF‐2011‐02350046

COronary endothelium and systemic METabolism crosstalk in the progression of cardiac dysfunction. CO‐MET study



RF‐2011‐02350034

Characterization of colon cancer stem cells for the identification of new

prognosticmarkers and/or targets for novel anticancer therapies

Basilicata Biomedical Oncology 1 ‐ Basic Translational 14,5Oncology

RF‐2011‐02348525

Involvement of mutant p53 gain of function in tumor microenvironment


RF‐2011‐02349450

Role of autophagy and its regulators in melanoma and in the differential therapeutic response to BRAF‐inhibitors


RF‐2011‐02351319

Treatment of early osteoarthritis by death‐inducible, IL‐10 expressing adipose‐derived stem cells: a novel, safe, anti‐inflammatory and regenerative approach.

GALEAZZI Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02348017

PRE‐TRANSPLANT GRAFT RECONDITIONING WITH MESENCHYMAL STROMAL CELLS IN EXPERIMENTAL KIDNEY TRANSPLANTATION

SAN MATTEO Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02351064

ALTERED HOST‐MICROBE INTERACTION IN HIV: A POTENTIAL TARGET FOR INTERVENTION WITH PROBIOTICS

Lombardia Clinical AIDS and Related Research 14,5Infection and immunity

Pagina 87 di 231



SCORE.


STRATEGICA

RF‐2011‐02352161

Innovative diagnostic tools for the control of patulin in the agri‐food chain


RF‐2011‐02347544

Studies on the molecular characteristics of the Env protein from HIV‐1 subtypes and recombinant forms circulating in Cameroon and their correlation with disease stage, virus infectivity and resistance to neutralization


RF‐2011‐02347507

PTPRG as a new candidate biomarker for Chronic Myeloid Leukemia

Sardegna Biomedical Oncology 1 ‐ Basic Translational 14,5Oncology

RF‐2011‐02347497

Cortical TRPV1 in neuroglial network: a new tool for studying neuropathic pain



RF‐2011‐02350512

High throughput technologies for uncovering new diagnostic biomarkers involved in the accelerated vascular ageing of patients with chronic kidney disease

Puglia Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02349818

Biomarkers and Asphyxia Piemonte Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349696

Pathogenesis of hemolytic uremic syndrome associated with Shiga toxin‐

producingEscherichia coli infections: early enrolment of patients with bloody diarrhea, application of over‐hydration protocols, and study of the kinetic of the toxins in blood



Pagina 88 di 231



SCORE.


STRATEGICA

RF‐2011‐02347913

Circulating microRNAs associated to cardiac‐derived microparticles and their role in endothelial dysfunction: age‐dependence of their expression in stable angina patients and following acute myocardial infarction

I.N.R.C.A. Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02349208

Mucosal and Systemic immunological and genetic correlates of HIV resistance in

exposed HIV‐seronegative individuals

Lombardia Clinical AIDS and Related Research 14,5Infection and immunity

RF‐2011‐02347604

Type 3 ryanodine receptor in post‐stroke recovery: genetic, cellular and functional study.

CARLO BESTA Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02351133

Rehabilitative Homework tool in young adults with Down syndrome to prevent cognitive decline: neuropsychological and clinical study.



RF‐2011‐02351263

Educational intervention to reduce sugar‐sweetened beverages purchase at the supermarket. A community trial.



RF‐2011‐02351948

Adolescents and young adults with cancer in Italy (AYACI)

IST.TUMORI MILANO Clinical Population Sciences and Epidemiology

14,5Oncology

RF‐2011‐02351013

Improving appropriateness of biopharmaceutical treatments in Multiple Sclerosis: early identification of non responders, dosage and timing redefinition, mechanism of action and neurotoxicity of an "old" and a "new" drugs.



Pagina 89 di 231



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STRATEGICA

RF‐2011‐02351056

Epigenetic analyses in heart failure Piemonte Biomedical Genes, Genomes and Genetics 14,5Metabolism disorders and cardiovascular disease

RF‐2011‐02348667

Intraoperative Calcitonin Monitoring as marker of disease cure after surgery and indicator of type of surgery in patients

withMedullary Thyroid Cancer

PASCALE Clinical Oncology 2 ‐ Translational Clinical 14,5Oncology

RF‐2011‐02349062

Role of microRNA regulation by estrogen receptor beta in hormone‐responsive breast cancer


RF‐2011‐02350663

Involvement of p63 in tumor development, invasion and metastasis, and its relationship with the other members of the p53 family

IDI Biomedical Cell Biology 14,5Oncology

RF‐2011‐02350653

Erdheim‐Chester disease at the crossroad between clonality and inflammation:

implications for therapy


RF‐2011‐02350790

Evaluation of the antitumor response of a co‐treatment with LHRH analogues in women with endometrial cancer at the

initial diagnosis

Toscana Clinical Oncology 2 ‐ Translational Clinical 14,5Oncology

RF‐2011‐02350722

Role of transmembrane chemokines in neuroprotection following brain ischemia



RF‐2011‐02352717

Employment of mesenchymal stem cells as vectors for prodrug activating enzymes in prostate cancer therapy


Pagina 90 di 231



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STRATEGICA

RF‐2011‐02350642

Prediction of preeclampsia:a proteomic approach for identification of novel biomarkers



RF‐2011‐02349127

Melanocortin‐1 receptor as a regulator of proliferation pathways in melanoma

SAN GALLICANO Biomedical Oncology 1 ‐ Basic Translational 14,5Oncology

RF‐2011‐02348665

Identification of novel therapeutic targets to halt HCV infection: a proteomic approach.



RF‐2011‐02347883

Regulation of kinetochore activity by the conserved cell cycle kinase Rio1

I.E.O. Biomedical Cell Biology 14,75Oncology

RF‐2011‐02349791

Sentinel animals to monitor asbestos pollution around the former Balangero mine

Piemonte Biomedical Population Sciences and Epidemiology


RF‐2011‐02348154

DEVELOPMENT AND CLINICAL APPLICATION OF A NEW BETA PROBE FOR RADIOGUIDED SURGERY IN MENINGIOMA TUMOR

CARLO BESTA Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02350754

Role of metabotropic glutamate receptor in absence epilepsy



RF‐2011‐02346752

Genetic and immunological factors involved in natural resistance to lentiviral infection


RF‐2011‐02349250

DEVELOPMENT OF NEW DIAGNOSTIC TOOLS FOR THE DETECTION OF ONCOGENIC POLYOMAVIRUSES IN HUMAN TUMORS.



Pagina 91 di 231



SCORE.


STRATEGICA

RF‐2011‐02348140

Levosimendan in high risk patients undergoing non cardiac surgery. A randomized study.

SAN RAFFAELE Milano Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02349076

Assessment and management of cardiovascular risk in perimenopausal women undergoing breast cancer screening

AUXOLOGICO Clinical Healthcare Delivery and Methodologies


RF‐2011‐02346876

Stimulating the left Broca's area to rehabilitate verbal communicative abilities in severe post‐stroke aphasia



RF‐2011‐02347511

GENETIC REGULATION OF PLASMA LOW DENSITY LIPOPROTEIN LEVELS. EFFECT OF MUTATIONS OF APOB AND ANGPTL3/8 GENES ON HEPATIC SECRETION OF APOB‐CONTAINING LIPOPROTEINS.

Emilia‐Romagna Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02351048

Marine omega‐3 fatty acids and vitamin D for QTc prolongation in people with psychosis on antipsychotic drugs.

SAN MATTEO Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02352063

Biomarkers in Glaucoma. BIETTI Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349090

Bisphenol A, obesity and breast cancer: epidemiological, clinical, analytical and biological approach

PASCALE Biomedical Oncology 1 ‐ Basic Translational 15Oncology

RF‐2011‐02346898

Burden of alcohol‐related diseases and priorities for health policy control.

ISS Biomedical Population Sciences and Epidemiology

15Oncology

Pagina 92 di 231



SCORE.


STRATEGICA

RF‐2011‐02348228

Molecular analysis of Streptococcus pneumoniae and Neisseria meningitidis serotypes/serogroups and potential coverage of available vaccines.

Toscana Biomedical Immunology 15Infection and immunity

RF‐2011‐02347308

Biochemical, electrophysiological and genetic determinants of disease progression and survival in Amyotrophic Lateral Sclerosis (ALS)

Sicilia Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02347297

TARGETING CD99 TO TREAT EWING SARCOMA


RF‐2011‐02351583

Acute coronary syndromes in diabetic and non‐diabetic patients: differences in the inflammatory, immunological, and coagulation events.



RF‐2011‐02350460

Genetics of dementia: transcriptional profiles in leukocytes for the identification of biomarkers associated to disease onset, phenotype and progression.



RF‐2011‐02351646

Assessment of animal welfare in extensive farms of Mediterranean Area: dairy ewes and buffaloes

IZS Sardegna Biomedical Veterinary 15Food safety and animal welfare

RF‐2011‐02350842

In search of new drugs and drug‐targets for the diagnosis and therapy of Invasive Fungal Infections (IFIs)



Pagina 93 di 231



SCORE.


STRATEGICA

RF‐2011‐02347679

Azacitidine, Depsipeptide and IFN‐alpha (ADI)‐combined treatment of colorectal cancer (CRC): depicting the therapeutic cross‐talk between epigenetic and IFN signatures


RF‐2011‐02351712

Use of polydeoxyribonucleotide for treating diabetic foot ulcers



RF‐2011‐02352273

Telemonitoring in Pediatric Patients with Heart Failure and VAD



RF‐2011‐02352893

Atherosclerotic effects of chronic low dose radiation exposure assessed with an integrated clinical, cellular and experimental approach: The Interventional Cardiologist Radiation Study

Lombardia Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02349952

Significance of Sentinel Node Micrometastasis in Breast Cancer Progression

C.R.O. AVIANO Clinical Oncology 2 ‐ Translational Clinical 15Oncology

RF‐2011‐02352263

Meta‐analytic assessment of mesenchymal stem cell genomic features in soft tissue sarcomas: a link to cancer dormancy and micro‐metastatic spread for improved prognosis and response to the therapy assessment

IST.TUMORI MILANO Biomedical Genes, Genomes and Genetics 15Oncology

Pagina 94 di 231



SCORE.


STRATEGICA

RF‐2011‐02351071

Cellular and Molecular events related to neuroprotection and modulation of endogenous neurogenesis: role of estrogens in an in vivo model of hippocampal neurodegeneration.




RF‐2011‐02351680

A diagnostic and therapeutic consensus approach to multiple sclerosis in the neurological network of Verona province



RF‐2011‐02351776

Comparison of the long‐term efficacy of bariatric surgery and new antidiabetic (GLP‐1 based) therapy on diabetes remission and cardiovascular risk profile in obese type 2 diabetic patients

Campania Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351660

ARIEL‐ Air Pollution and Cardiovascular Risk Investigations: the Epigenomic Link

MAGGIORE Biomedical Genes, Genomes and Genetics 15Metabolism disorders and cardiovascular disease

RF‐2011‐02351296

Molecular identification of new poor prognostic subgroups of childhood Acute Lymphoblastic Leukemia as candidate for targeted therapies


RF‐2011‐02349056

The effect of metabolic surgery on the immunometabolome profile in non obese type 2 diabetic patients



RF‐2011‐02350774

Targeting inflammasome for seizure prevention



Pagina 95 di 231



SCORE.


STRATEGICA

RF‐2011‐02348210

Cognitive dysfunction after general anesthesia in the elderly: a transient, reversible phenomenon or the harbinger of Alzheimer disease?



RF‐2011‐02350256

18F‐AH‐111585 PET/CT in the diagnosis and evaluation of tumor angiogenesis in primary brain tumors

HUMANITAS Clinical Oncology 2 ‐ Translational Clinical 15Oncology

RF‐2011‐02346851

Antimicrobial Microbubbles (MBs) for treatment of biofilm‐associated infections



RF‐2011‐02350124

THE ROLE OF THE GUT MICROBIOTA IN ALZHEIMER'S DISEASE PATHOGENESIS



RF‐2011‐02351555

Methylene blue in hypotensive vasoplegic patients. A randomized trial.



RF‐2011‐02350569

A MULTICENTRE PHASE II RANDOMIZED STUDY OF FULVESTRANT VERSUS FULVESTRANT + METFORMIN AS FIRST‐ AND SECOND‐LINE ENDOCRINE TREATMENT IN NON DIABETIC POSTMENOPAUSAL WOMEN WITH HORMONE RECEPTOR POSITIVE, HER‐2 NEGATIVE ADVANCED BREAST CANCER. THE META TRIAL.


RF‐2011‐02347230

The role of Iron in White Matter changes in Neurodegenerative Diseases (Alzheimer, Parkinson and Huntington's Diseases). Does the white matter share with the gray matter the same physiopathology (iron accumulation)?



Pagina 96 di 231



SCORE.


STRATEGICA

RF‐2011‐02349354

DNA replication licensing in Plasmodia: molecular characterisation of a potential new therapeutic target for malaria treatment.



RF‐2011‐02351484

Evaluation of rubella immunity among pregnant women and development and evaluation of a postpartum and post‐abortion rubella vaccination protocol in a sample of Italian hospitals



RF‐2011‐02349134

New biomarkers to predict prognosis and tailor systemic therapy in patients with Pseudomyxoma Peritonei


RF‐2011‐02349296

Combined study of genomic CNVs and immunological profiles in a population of patients with Autistim Spectrum Disorders (ASD)

AUXOLOGICO Biomedical Genes, Genomes and Genetics 15Neurological diseases

RF‐2011‐02348704

Zinc Finger Protein 423 as a candidate gene for Autism Spectrum Disorder susceptibility ‐ a comprehensive analysis in mouse mutants and autistic children.

SAN RAFFAELE Milano Biomedical Biobehavioral and Behavioral Processes


RF‐2011‐02347107

Upper limb impairment in Charcot‐Marie‐Tooth patients: motor strategies, impact on quality of life and cortical functional reorganization

DON GNOCCHI Clinical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02348635

Charcot Foot: whole genome analysis and inflammatory evaluation for the development of potential treatment strategies

I.N.R.C.A. Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


Pagina 97 di 231



SCORE.


STRATEGICA

RF‐2011‐02346956

Association between environmental exposure to chemical pollutants and the development of neurodegenerative diseases: a clinical epidemiological study combinated with environmental and biomolecular observations in contaminated Terzigno area

Campania Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02351018

Risk of cardiovascular disease in breast cancer patients: a population based study


15Oncology

RF‐2011‐02349403

Identification of genetic determinants for cetuximab‐induced immunogenic cell death and response to treatment


RF‐2011‐02349247

INNOVATIVE TREATMENTS FOR OSTEOSARCOMA: VALIDATION OF PROTEIN KINASE INHIBITORS AS TARGETED DRUGS AND ABC TRANSPORTERS INTERACTING AGENTS


RF‐2011‐02347866

A registry of intravenous artesunate for severe malaria in returning travelers from endemic countries: pharmacokinetic data, adverse events, and clinical outcome. NetwOrk for severe MALaria treatment ‐ NOMAL study



RF‐2011‐02352697

Behavioral and neurofunctional markers of spatial awareness deficits during multi‐tasking: Implications for diagnosis and rehabilitation of right hemisphere stroke patients

S.CAMILLO Clinical Biobehavioral and Behavioral Processes


Pagina 98 di 231



SCORE.


STRATEGICA

RF‐2011‐02347087

HIV‐TLR4 interaction as a novel target for intervention strategies against HIV disease


RF‐2011‐02348308

Mild cognitive impairment and progression to Alzheimer's disease: association with herpes viruses infections.

Emilia‐Romagna Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02352605

Generation and validation of a new breast cancer prognostic signature by RNAseq‐based translatome profiling.

Provincia autonoma Trento Biomedical Oncology 1 ‐ Basic Translational 15,25Oncology

RF‐2011‐02347561

BRAIN MACHINE INTERFACE (BMI) IN PARALYSIS

S.CAMILLO Clinical Biobehavioral and Behavioral Processes


RF‐2011‐02347982

Spinal cord modular organization in recovery and back to work management of ataxic subjects

INAIL Biomedical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02352180

Exome sequencing in Individuals with Developmental Delay/Intellectual Disability of Unknown Etiology


Biomedical Genes, Genomes and Genetics 15,5The new biotechnologies

RF‐2011‐02351338

Project Title: Development of a dedicated evaluation track within the Hospital and a network between the Hospital and family doctors for the identification, evaluation and management of patients with

osteoporotic fractures



RF‐2011‐02348799

Stereotactic body radiotherapy as monotherapy or boost combined with

externalbeam radiotherapy for localized prostate cancer


Pagina 99 di 231



SCORE.


STRATEGICA

RF‐2011‐02351307

A Next‐Generation Sequencing approach to assess blood‐based transcriptomic biomarkers in Coronary Artery Disease

MONZINO Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02349167

GENETIC AND NEUROBIOLOGICAL INFLUENCES ON RISK‐TAKING PROPENSITY



RF‐2011‐02352178

Multimodal evaluation of stroke patient's mindbrain state during upper‐limb robot‐aided therapy


Clinical Emerging Technologies and Training in Neurosciences


RF‐2011‐02348971

Development of a diagnostic, histopathologic and therapeutic program for the management of gastrointestinal motor disorders in Parkinson disease: proposal of a new translational collaborative approach



RF‐2011‐02348657

Development and validation of predictive models of toxicity after radiotherapy for prostate cancer based on large data‐bases from clinical trials


RF‐2011‐02351222

EGFR‐TK inhibitors vs Chemotherapy: Improving Treatment Selection for Non Small Cell Lung Cancer (NSCLC) Patients using VeristratTM Serum Proteomic Profile Classification and Serum Amyloid A


RF‐2011‐02346756

Surveillance, control and prevention of infections by multidrug resistant organisms in alternative healthcare settings: nursing and residential homes

Sicilia Clinical Healthcare Delivery and Methodologies


Pagina 100 di 231



SCORE.


STRATEGICA

RF‐2011‐02349264

Insights into epigenetic changes in hepatocellular carcinoma and rationales for their therapeutic targeting


RF‐2011‐02348928

Innovative strategies for preventing emergence and transmission of multi drug

resistantGram negative bacteria in hospitalized newborns, infants, and children


Clinical Population Sciences and Epidemiology


RF‐2011‐02349857

BONE AND MUSCLE IN SPINAL MUSCULAR ATROPHY: FROM BENCH TO BEDSIDE.

AUXOLOGICO Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02347855

The role of the EGFR in the interaction between mesenchymal stem cells and breast cancer cells: implications for novel therapeutic approaches


RF‐2011‐02349826

Structural connectivity in DYT1 and DYT6 dystonia



RF‐2011‐02346772

Novel therapeutic strategies for Amyotrophic Lateral Sclerosis: testing the efficacy of cell‐permeable peptides in preclinical models.

MAUGERI Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349896

HIV‐infected pregnant women treated with HAART: registry of pharmacokinetic parameters of new and commonly used antiretrovirals; mitochondrial toxicity and apoptosis in pregnant women and utero‐exposed newborn

SPALLANZANI Clinical AIDS and Related Research 15,5Infection and immunity

Pagina 101 di 231



SCORE.


STRATEGICA

RF‐2011‐02352228

PROGNOSTIC ROLE OF CARDIOPULMONARY EXERCISE STRESS TEST IN MODERATE‐TO‐SEVERE AORTIC STENOSIS

SAN DONATO Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02349788

Increased severity of respiratory viral infections in the elderly: identification of thiols level as biomarker and therapeutic target.




RF‐2011‐02346793

Eukaryotic translation Initiation Factor 4H /Wbscr1: its role in gametogenesis, fertility and gonadal carcinogenesis



RF‐2011‐02352307

EVALUATION OF THE ACTIVITY OF A NOVEL PARTIAL AGONIST OF A1

ADENOSINERECEPTOR AS POTENTIAL THERAPEUTIC AGENT FOR DIABETES AND OBESITY

Abruzzo Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02350657

Novel biological agents for the treatment of hormone‐refractory prostate cancer



RF‐2011‐02351922

Clinical and neurobiological correlates of repetitive transcranial magnetic stimulation (rTMS) in Alzheimer's disease



RF‐2011‐02352284

Pathophysiologic and prognostic role of OXidative stress in acute coronarY sindromes: GENder differences [OXYGEN trial]

Lazio Clinical Cardiovascular and Respiratory Sciences


Pagina 102 di 231



SCORE.


STRATEGICA

RF‐2011‐02349128

Avian reservoirs as a potential source of human extraintestinal pathogenic Escherichia coli



RF‐2011‐02348719

Masked mycotoxins in cereal‐based food products. Analytical methods, evaluation of their occurrence and risk assessment: an emerging issue for food safety?


RF‐2011‐02348256

Molecular characterization of the T cell dysfunctions during HIV infection to evaluate immune restoration after HAART and plan new immunotherapeutic strategies

Emilia‐Romagna Biomedical AIDS and Related Research 15,5Infection and immunity

RF‐2011‐02347345

Identification of early neurophysiological markers of cognitive‐behavioural disturbances in patients with cerebrovascular disease.

Sicilia Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02351004

Postoperative radiotherapy to the chest wall or the breast plus draining nodes in breast cancer patients: dosimetric comparison between 3DCRT, IMRT, helical tomotherapy and TomoDirect tomotherapy.

Umbria Clinical Oncology 2 ‐ Translational Clinical 15,5Oncology

RF‐2011‐02349571

Cerebral Amyloid Angiopathy: new markers for early diagnosis and insights in pathogenetic mechanism

AUXOLOGICO Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02348100

Impact of defective DNA repair of oxidative damage on the immune response and relevance for colorectal cancer


Pagina 103 di 231



SCORE.


STRATEGICA

RF‐2011‐02349205

Cell characterization and analysis of the proliferative/differentiative potential of human coelomic fluid cells for "in

utero"haematopoietic stem cell transplantation in haemoglobinopathies

Sicilia Biomedical Vascular and Hematology 15,5The new biotechnologies

RF‐2011‐02351010

Glioma‐associated stem cells: an innovative patient based approach for prognostic, predictive and therapeutic purposes.

Friuli‐Venezia Giulia Clinical Brain Disorders and Clinical Neuroscience

15,5Oncology

RF‐2011‐02351783

Sleep‐wake cycle and Sundown Syndrome in Alzheimer Disease: role of the orexinergic system and relationships with neurodegeneration biomarkers



RF‐2011‐02348300

Cross‐talk between innate and adaptive immunity as a target for therapeutic immune intervention in the early phases of psoriasis pathogenesis


RF‐2011‐02350388

Cell Stess Derived Primary Cell Transformation

SDN Biomedical Oncology 1 ‐ Basic Translational 15,5Oncology

RF‐2011‐02351053

NEW BIOMARKERS IN WORKERS EXPOSED TO INORGANIC ARSENIC

MAUGERI Biomedical Population Sciences and Epidemiology


RF‐2011‐02351944

Focal Cortical Dysplasia Type I and Type II: Identification of causative genes and elucidation of disease pathomechanisms



Pagina 104 di 231



SCORE.


STRATEGICA

RF‐2011‐02347480

ANTI‐INFLAMMATORY ACTIVITY OF POLYPHENOLS IN CANCER CHEMOPREVENTION: IN VITRO AND IN VIVO STUDIES



RF‐2011‐02347471

New frontiers in breast imaging: contrast enhanced digital mammography. ‐ Clinical performance of contrast‐enhanced spectral mammography (CESM ‐ SenoBright) in pre‐surgical evaluation of extent of malignancy in a population of women with breast cancer


RF‐2011‐02351454

Microglial markers of central sensitization in neuropathic pain. A translational study



RF‐2011‐02351920

PAIN‐ASSOCIATED CORTICAL HEMODYNAMIC PERTURBATION IN PRETERM NEWBORNS AND ITS RELATION WITH NEURODEVELOPMENTAL OUTCOME

BURLO GAROFALO Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349416

Role of the menstrual cycle and of sexual hormones in HIV‐1 infection of human cervico‐vaginal tissue explants


RF‐2011‐02349083

Molecular Biomarkers for Colorectal Liver Metastases Resectability after Chemotherapy with Cetuximab

REGINA ELENA Clinical Oncology 2 ‐ Translational Clinical 15,5Oncology

RF‐2011‐02350459

Impact of Carotid Endarterectomy and STenting on RhEological parameters and Autonomic Modulation (ICE‐STREAM study).



Pagina 105 di 231



SCORE.


STRATEGICA

RF‐2011‐02349515

HIGH THROUGHPUT TECNOLOGIES FOR UNCOVERING NEW DIAGNOSTIC BIOMARKERS FOR EARLY DIAGNOSIS OF CHRONIC ALLOGRAFT INJURY IN RENAL TRANSPLANTATION (CAI)

Puglia Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02349543

Automated Good Manufacturing Production of Adipose‐derived Mesenchymal Stem Cells for clinical use: validation, characterization and biosafety.

RIZZOLI Clinical Bioengineering Sciences and Technologies


RF‐2011‐02352071

Pharmacological resistance in pituitary tumours: insights from the study of Aryl hydrocarbon Receptor Interacting Protein (AIP) as a new mediator of somatostatin analogues

Abruzzo Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences

15,75Oncology

RF‐2011‐02352772

NEW DIAGNOSTIC METHODS FOR PERSONALIZED MEDICINE: AUTOMATIC GENERATION OF CLINICAL PATHWAY TROUGHT CORRELATION BETWEEN BIOCHEMICAL SCREENING AND STRESS IMAGING

Marche Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02352689

Optimization of In vitro and In vivo tissue engineering of functional mammary gland and uterus for prospective translational clinical application in post‐oncologic reconstructive surgery.



Pagina 106 di 231



SCORE.


STRATEGICA

RF‐2011‐02348668

Innovative approaches for the treatment of Pompe disease: identification of potential therapeutic targets in patients with the common splicing mutation c.‐32‐13T>G and pharmacological chaperoning of alpha glucosidase.

Friuli‐Venezia Giulia Biomedical Genes, Genomes and Genetics 15,75Metabolism disorders and cardiovascular disease

RF‐2011‐02350348

Acoustic Spectroscopy of Lung Toscana Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02347756

Retinal vascular imaging and risk of target organ damage among patients with suspected hypertension in primary care



RF‐2011‐02351459

INTEGRATION OF GENOMIC MEDICINE: THE USE OF ADPKD AS A MODEL

Emilia‐Romagna Biomedical Genes, Genomes and Genetics 15,75The new biotechnologies

RF‐2011‐02351024

Genetic polymorphisms and noninvasive scores for screening patients with

progressive nonalcoholicfatty liver disease (NAFLD): an international multicenter collaborative study

Piemonte Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02348911

Microbiome assessment in the myocardial tissue of patients with dilated cardiomyopathy and myocarditis negative to the known cardiotropic viruses.



RF‐2011‐02348410

Using structural and functional MRI to assess the effects of motor rehabilitation on brain plasticity in multiple sclerosis: a double‐blind, randomized, controlled study



Pagina 107 di 231



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STRATEGICA

RF‐2011‐02349546

Analysis of the host pharmacogenetic background for prediction of outcome and toxicity in mantle cell lymphoma (MCL) treated with R‐HDS


RF‐2011‐02348888

Oncolytic Properties of Influenza A Viruses in Human Pancreatic Tumour Cells and Xenograft Models

IZS Venezie Biomedical Oncology 2 ‐ Translational Clinical 16Oncology

RF‐2011‐02347708

Host genetic factors and response to dendritic cells based immune treatment in HIV‐1 infected patients

BURLO GAROFALO Clinical AIDS and Related Research 16Infection and immunity

RF‐2011‐02348608

Safe production of 99mTc with a biomedical cyclotron

Emilia‐Romagna Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02349307

Study of the molecular mechanisms underlying the susceptibility to neonatal group B streptococcal disease

SAN MATTEO Biomedical Immunology 16Infection and immunity

RF‐2011‐02348052

Brain proteoglycans as disease prediction genes and therapeutic targets in Multiple Sclerosis.

Puglia Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02348110

Identification of novel biomolecular targets of pets spontaneous carcinomas for the development of new diagnostic and therapeutics approaches: use of the human knowledge to accelerate the management of pets tumors.


Biomedical Veterinary 16Oncology

Pagina 108 di 231



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STRATEGICA

RF‐2011‐02348181

UNRAVELING THE PROTEOSTASIS NETWORK TO ADDRESS CONFORMATIONAL DISORDERS

GASLINI Biomedical Genes, Genomes and Genetics 16Metabolism disorders and cardiovascular disease

RF‐2011‐02349063

Identification of new biomarkers of colorectal cancer


RF‐2011‐02351559

Can we predict the degradation of cognitive status in hearing loss subjects with mild cognitive impairment based on "fluid", neurophysiological and neuroimaging markers?




RF‐2011‐02349715

Preclinical and phase II clinical study of cisplatin, cetuximab and valproic acid in recurrent and/or metastatic squamous cell carcinoma of the head and neck

PASCALE Clinical Oncology 2 ‐ Translational Clinical 16Oncology

RF‐2011‐02351708

Chemogenomics in drug discovery for regenerative therapies of common and rare myelin diseases



RF‐2011‐02348803

Pathophysiological mechanisms of fibrosis: molecular characterization in a cell based assay.

CARLO BESTA Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02352046

Hepatitis C virus‐host lipoproteins interplay: development of new antiviral strategies.



RF‐2011‐02348788

Characterization of the relationship of microbiota, Vitamin D, and mucins towards new colorectal cancer prevention strategies.


Pagina 109 di 231



SCORE.


STRATEGICA

RF‐2011‐02349658

STUDY OF CONSORTIA OF PROBIOTICS USED TO IMPROVE HUMAN HEALTH



RF‐2011‐02349040

Definition of a clinical and immunological phenotype of antibody mediated rejection in heart transplant recipients: prognostic and therapeutic implications

Emilia‐Romagna Clinical Immunology 16Infection and immunity

RF‐2011‐02349785

DEVELOPMENT OF A NEW NON‐RECOMBINANT MUCOSAL VACCINE DELIVERY SYSTEM

Toscana Biomedical Immunology 16The new biotechnologies

RF‐2011‐02349859

Detection of blood‐borne EMT cells and risk of metastasis in colorectal cancer patients.

HUMANITAS Biomedical Oncology 2 ‐ Translational Clinical 16Oncology

RF‐2011‐02351532

Birth outcomes in women with cancer: a population based cohort study

IST.TUMORI MILANO Clinical Population Sciences and Epidemiology

16Oncology

RF‐2011‐02349861

Phenotypes in Dyslexia with genetic alteration: sensory and neuronal deficits.

STELLA MARIS Clinical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02348670

Macrophage Senescence in Alzheimer Disease: possible link with onset and progression of the disease.

I.N.R.C.A. Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02352739

Role of nanomultilayers with anti‐inflammatory and tracking features in human islet transplantation for the treatment of type 1 diabetes



Pagina 110 di 231



SCORE.


STRATEGICA

RF‐2011‐02347626

Selective targeting of Lyn kinase and potassium channels by nocodazole and psoralen analogs in malignant cells to define innovative strategies for therapy in B‐cell chronic lymphocytic leukemia

Veneto Biomedical Oncology 2 ‐ Translational Clinical 16Oncology

RF‐2011‐02347574

HCV Direct Acting Antivirals (DAA) and antiretroviral drugs in pregnant women: a comprehensive surveillance/research program on maternal and neonatal safety, treatment policies, immunovirology and pharmacokinetics.



RF‐2011‐02352655

New approach for the treatment of B‐cell disorders via antiCD20 nanoparticles

Friuli‐Venezia Giulia Biomedical Oncology 1 ‐ Basic Translational 16Oncology

RF‐2011‐02350683

Ebstein‐virus (EBV) and Human herpesvirus 6 (HHV‐6) infection in Multiple Sclerosis: a trigger for autoimmunity



RF‐2011‐02346842

Development of theranostic agents targeting molecular pathways involved in cell migration and metastases


RF‐2011‐02347425

A pharmacological chaperone approach to rescue nucleophosmin mutants in acute myeloid leukemia

Abruzzo Biomedical Biological Chemistry and Macromolecular Biophysics

16Oncology

RF‐2011‐02350174

Development and application of a novel Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) functional test in leukocytes

Veneto Biomedical Cardiovascular and Respiratory Sciences


Pagina 111 di 231



SCORE.


STRATEGICA

RF‐2011‐02352802

The role of OPG, RANK and RANKL gene SNPs (single nucleotide polymorphisms) in susceptibility to acute myocardial infarction


Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02350377

In situ proteomics profiling of membranous glomerulonephritis

Lombardia Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02352420

Enabling bedside neurophysiological assessment and communication in functional Locked‐in syndromes after acquired brain injury



RF‐2011‐02347052

Biomechanical Modeling for Customized Surgical Planning in the Cartilage Treatment of the Patello‐Femoral Joint.

RIZZOLI Clinical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02352301

Overcome resistance of mTOR inhibitor in renal clear cell carcinoma targeting autophagy: a preclinical and clinical study.

Lazio Biomedical Oncology 2 ‐ Translational Clinical 16Oncology

RF‐2011‐02350318

Role of Interleukins and LOX‐1 in Niemann‐Pick Type C Disease Neurodegeneration: possible new therapeutic targets and biomarkers.



RF‐2011‐02350873

AUDIT clinico e percorsi di miglioramento nelle cure dei pazienti con infezione nelle unità di pneumologia ad alta intensità di cura (UTIR, unità di terapia intensiva respiratoria e UMR, Unità di Monitoraggio Respiratorio) della REGIONE

LOMBARDIAClinical



Pagina 112 di 231



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STRATEGICA

RF‐2011‐02351170

NEW STRATEGY FOR DRUG DELIVERY IN PHOTODYNAMIC THERAPY OF GLIOBLASTOMA


16Oncology

RF‐2011‐02352479

PHOSPHATE HOMEOSTATIS AND PATHOGENESIS OF MINERAL AND CARDIOVASCULAR DISORDERS




RF‐2011‐02352289

Stereo‐body radiotherapy: a novel software expert system based on the optimization of treatment schedules

IRST Meldola Clinical Oncology 2 ‐ Translational Clinical 16Oncology

RF‐2011‐02346980

Novel biocomposite for cranial bone regeneration in pediatric patients

Lazio Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02350831

Innovative treatment of Primary Progressive Aphasias (PPA) using transcranial direct current stimulation (tDCS) combined with language training



RF‐2011‐02352818

Influenza vaccination of the elderly: effectiveness and determinants assessment by systematic literature review and by a historical cohort study based on 13 years of mass campaigns in Lazio and Piemonte regions

Lazio Clinical Infectious Diseases and Microbiology


RF‐2011‐02350469

Biological bank to identify markers of disease activity related to clinical variables and modifying drugs in multiple sclerosis

Emilia‐Romagna Clinical Immunology 16Neurological diseases

Pagina 113 di 231



SCORE.


STRATEGICA

RF‐2011‐02352623

Development of new disease biomarkers by laboratory applications as diagnostic and prognostic tools for Amyotrophic Lateral Sclerosis



RF‐2011‐02351043

The BRCAness profile: from the molecular basis to the clinical relevance


RF‐2011‐02347559

Preclinical evaluation of isoform‐specific PI3K inhibitors' effects in IPF for novel

potentialtherapies of malignat mesenchymal tumors

Sicilia Biomedical Oncology 2 ‐ Translational Clinical 16Oncology

RF‐2011‐02352507

Inflammatory biomarkers in phenotyped COPD: relation to extrapulmonary manifestations and dysmetabolism.



RF‐2011‐02350960

A mirror‐neurons based stimulation protocol (MNSP) to improve language and behavior in mild to moderate people with Alzheimer Disease

DON GNOCCHI Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02352510

New methodologies for non‐invasive, quantitative and Automatic MOnitoring of childbirth LABor (AMOLAB)

Puglia Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02347275

Targeting Tenascin‐C to inhibit early lymph node colonization by prostate cancer stem/initiating cells and immune evasion


Pagina 114 di 231



SCORE.


STRATEGICA

RF‐2011‐02352598

Investigation of the association between NF1 gene and NF1‐related genes transcriptional profile and high risk of tumor‐development in patients affected by

Neurofibromatosis type 1.

Campania Biomedical Oncology 1 ‐ Basic Translational 16Oncology

RF‐2011‐02347032

Molecular factors predictive of heart and brain involvement in myotonic dystrophy

S.CAMILLO Clinical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02350624

The use of biomarkers in the clinical study of multiple exposure to chemicals: new diagnostic strategies to evaluate human health risk.



RF‐2011‐02349084

Circulating microRNAs as biomarkers of cardiovascular inflammatory diseases

HUMANITAS Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02352617

NEW INSIGHTS FOR CAD PATIENT MANAGEMENT: in vivo assessment of coronary plaque morphology by means of OCT images and biohumoral markers (PLIMAB: PLaque IMAging Biomarkers)



RF‐2011‐02348977

Proof of concept for a new organizational model of care delivery: the Personalized Medicine approach to the treatment of Idiopathic Environmental Intolerance

Lazio Biomedical Healthcare Delivery and Methodologies


RF‐2011‐02352607

Protocol and tools towards an investigation of low dose effects in advanced radiation therapy modalities.

Piemonte Biomedical Healthcare Delivery and Methodologies

16,5Oncology

Pagina 115 di 231



SCORE.


STRATEGICA

RF‐2011‐02351047

GENetics of familial and sporadic Lone Atrial Fibrillation (GenLAF)

SAN MATTEO Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02347249

Evaluation of the prognostic role of phosphatidylinositol 3‐kinase pathway mutations through analysis of peripheral blood and circulating tumor cells in metastatic breast cancer patients treated with endocrine therapy


RF‐2011‐02352321

Implementing Active Surveillance for low risk prostate cancer patients: a population‐based cohort study in the Oncological Network of Piemonte and Valle d'Aosta. The PROstate CanceR Active Surveillance sTudy (PROCRAST).


16,5Oncology

RF‐2011‐02350967

THE OUTCOME OF DEPRESSION AND TYPE 2 DIABETES MELLITUS WHEN THEY ARE COMORBID: A COMPARISON BETWEEN TELEMEDICINE‐ASSISTED CARE AND TREATMENT AS USUAL

Veneto Clinical Biobehavioral and Behavioral Processes


RF‐2011‐02349210

Circulating microRNAs as prognostic biomarkers of arterial remodeling/restenosis after percutaneous transluminal intervention in patients with peripheral arterial disease

I.N.R.C.A. Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02351073

Serum and tissue miRs as biomarkers for diagnosis and prognosis of B‐NHL in chronically HBV or HCV‐infected patients

ISS Biomedical Oncology 2 ‐ Translational Clinical 16,5Infection and immunity

Pagina 116 di 231



SCORE.


STRATEGICA

RF‐2011‐02352068

GENERATION OF RED CELLS WITH RARE OR UNCOMMON BLOOD GROUP PHENOTYPES FROM HUMAN INDUCED PLURIPOTENT STEM CELLS (hiPSCs)

Lazio Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02348462

Puzzle: a multiparametric approach to clinical decision making and monitoring of children admitted to pediatric cardiac intensive care for congenital heart diseases




RF‐2011‐02350286

Role of autophagy core complex in tumor onset and progression

SANTA LUCIA Biomedical Cell Biology 16,5Oncology

RF‐2011‐02349306

Clinical markers of chilhood apraxia of speech and its neurobiological and genetic correlates



RF‐2011‐02348187

GENETIC INVOLVEMENT OF DESMOPLAKIN AND OTHER DESMOSOMAL PROTEINS IN DILATED CARDIOMYOPATHY

SAN MATTEO Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02347369

Neurorehabilitation of post‐stroke disorders using integrated behavioral and brain stimulation tools



RF‐2011‐02349235

Dissection of the MYCN/MAX/MAD transcription factor network as a critical

step to designnovel therapeutic approaches to treat pediatric neuroblastoma


RF‐2011‐02351361

Intranasal delivery of nano‐modified drugs for the treatment of glioblastoma


Pagina 117 di 231



SCORE.


STRATEGICA

RF‐2011‐02351879

Health impact assessment and health care costs of respiratory tract infections (RTIs) in general population and hospitalized patients

Sicilia Biomedical Population Sciences and Epidemiology


RF‐2011‐02351929

High throughput, population‐wide, reflex testing of GI cancer: biologic characterization, identification of individualized therapy targets and prevention of familial cases



RF‐2011‐02348159

Role of tumor microenvironment in thyroid carcinogenesis onset and progression: thyroid cells cross‐talk with macrophages

IST.TUMORI MILANO Biomedical Oncology 1 ‐ Basic Translational 16,5Oncology

RF‐2011‐02347360

Identification and characterization of genes involved in progenitor cells reprogramming into stem cells and cancer stem cells, as novel cancer therapeutic targets.


RF‐2011‐02348584

Unraveling the role of sodium channels in the susceptibility to neuropathic pain

CARLO BESTA Biomedical Genes, Genomes and Genetics 16,5Neurological diseases

RF‐2011‐02350620

A diagnostic innovative software for surgical planning in hip arthroplasty for patients with hip dysplasia to optimize functional recovery.

RIZZOLI Clinical Bioengineering Sciences and Technologies


RF‐2011‐02349919

DEVELOPMENT OF A NEW ARTIFICIAL HEART FOR PEDIATRIC PATIENTS WITH

END‐STAGE HEART FAILURE




Pagina 118 di 231



SCORE.


STRATEGICA

RF‐2011‐02350232

Ankrd2 as a novel repressor of immune and inflammatory responses through regulation of myokine expression.

HUMANITAS Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02350428

Molecular modeling of advanced/metastatic soft tissue sarcomas to develop evidence‐based therapeutic targets and circulatory biomarkers

RIZZOLI Biomedical Oncology 2 ‐ Translational Clinical 16,5Oncology

RF‐2011‐02346852

The extracellular matrix EMILIN2 as a key molecule regulating colon carcinogenesis and as a potential prognostic marker.


RF‐2011‐02347639

Integrated analysis of somatic mutations and related altered pathways for the identification of new biomarkers and molecular targets in tumors of the lower female genital tract.

PASCALE Clinical Oncology 1 ‐ Basic Translational 16,5Oncology

RF‐2011‐02351253

Early Retinal Neuroprotection as a Novel Tool to Achieve the Primary Prevention of Diabetic Retinopathy



RF‐2011‐02352296

Risk of metachronous cancer in genetically predisposed colorectal patients


RF‐2011‐02351652

Diagnostic, prognostic, and monitoring markers based on muscular, neurophysiological and neuroimaging markers in dystonic patients. A pilot clinical study

SDN Clinical Brain Disorders and Clinical Neuroscience


Pagina 119 di 231



SCORE.


STRATEGICA

RF‐2011‐02347786

A network of external quality controls for the molecular diagnosis of sporadic and hereditary cancers


16,5Oncology

RF‐2011‐02351419

TrkAIII expression in Glioblastoma: Significance in prognosis, relationship to therapeutic response and role in pathogenesis and progression.

Abruzzo Biomedical Oncology 2 ‐ Translational Clinical 16,5Oncology

RF‐2011‐02348249

New minimally invasive arthroscopical approach for the treatment and prevention of hip osteoarthritis

RIZZOLI Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02351409

Spatially variant prescription of dose radiation from hypoxic tumor distribution assessed by VEGF expression and biological imaging: a phases I‐II study in non small cell lung cancer

CROB Biomedical Oncology 2 ‐ Translational Clinical 16,5Oncology

RF‐2011‐02349955

Heart‐liver axis in metabolic syndrome: common damage mechanisms as an input for patient management




RF‐2011‐02346762

Evaluation of patient preferences around the different cancer services dimensions: new evidences for improving service organisation.


16,5Oncology

RF‐2011‐02347730

Modulating the inflammation of cerebral death to improve the survival of graft

Campania Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


Pagina 120 di 231



SCORE.


STRATEGICA

RF‐2011‐02348922

SILK BASED BASEMENT MEMBRANE MODEL: A NEW TOOL FOR THE STUDY OF PLATELET PRODUCTION, FUNCTIONALITY AND THERAPEUTIC APPROACHES

SAN MATTEO Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02350019

Natural history of Myotonic Dystrophy type 1. Epidemiology in the Lazio region, clinical protocol standardization, and assessment of clinical and molecular endpoints in a longitudinal cohort study.

SANTA LUCIA Clinical Population Sciences and Epidemiology


RF‐2011‐02348817

Prospective multicenter study on antibiotic prophylaxis protocol (ABP) for the prevention of Neurosurgical Surgical Site Infection (N‐SSIs), with taylored strategies for High Risk (HR) classes

CARLO BESTA Clinical Infectious Diseases and Microbiology


RF‐2011‐02351278

AFTEREIGHT study: anticipated boost with intraoperative electrons (IORT) followed by short‐course hypofractionated whole breast radiotherapy in early breast cancer patients.

I.E.O. Clinical Healthcare Delivery and Methodologies

16,5Oncology

RF‐2011‐02347027

THE ROLE OF CALCIUM HOMEOSTASIS IN CONGENITAL CEREBELLAR ATAXIAS : genetic dissection and functional characterization of a neuronal specific plasma membrane Ca2+ATPase




RF‐2011‐02349652

HIV INFECTION AND ANTIRETROVIRAL TREATMENT: EFFECTS ON BONE‐MARROW HEMATOPOIETIC STEM CELLS


Pagina 121 di 231



SCORE.


STRATEGICA

RF‐2011‐02350658

Translational approach to the cardiovascular effects of antipsychotics

Piemonte Biomedical Emerging Technologies and Training in Neurosciences


RF‐2011‐02349483

Development of an antimicrobial food packaging by using essential oils and nanotechnology ‐ EssencePack


RF‐2011‐02349130

Vagal nerve stimulation as a novel strategy to limit post‐ischemic injury and possibly to prevent the development of ischemic cardiomyopathy



RF‐2011‐02350156

Mother‐to‐infant transmission of infectious diseases: development of clinical pathways for an appropriate/comprehensive care of pregnant women with infections and their infants.


Clinical Infectious Diseases and Microbiology


RF‐2011‐02349119

Innovative biological markers in type 1 diabetes



RF‐2011‐02349484

WNV endemization in Italy: implications for the national transplant program



RF‐2011‐02352756

Comparative effectiveness: Hospital volumes and outcomes of treatments. Systematic reviews and observational study in Italian NHS.

AGENAS Clinical Healthcare Delivery and Methodologies


RF‐2011‐02350715

Aging‐related platelet transcriptome variations in atherothrombosis

Umbria Biomedical Biology of Development and Aging 16,5Metabolism disorders and cardiovascular disease

Pagina 122 di 231



SCORE.


STRATEGICA

RF‐2011‐02350422

Effects of a controlled exercise intervention in modulating endothelial dysfunction and related humoral markers in coronary patients with type 2 diabetes

DON GNOCCHI Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02351274

Imaging pREdictors of outcome after Surgical myOcardiaL revascUlarizaTION

[RESOLUTION trial]

Lazio Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02347273

New molecular markers of pathogenetic and translational significance in tumoral and peritumoral tissue of primary liver cancer

HUMANITAS Biomedical Oncology 1 ‐ Basic Translational 16,75Oncology

RF‐2011‐02349733

OVERWEIGHT/OBESITY/SEVERE OBESITY: TIME TRENDS AND LONGTERM BENEFITS OF WEIGHT REDUCTION



RF‐2011‐02352410

A tool to diagnose the impairment of aphasic patients and direct rehabilitation by analysing speech errors

SANTA LUCIA Clinical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02350588

Integrated approach to investigate the effect of environmental pollution on reproductive outcomes

Emilia‐Romagna Biomedical Genes, Genomes and Genetics 16,75Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02351556

In vivo model for tissue engineering of urethral reconstruction on bio‐absorbable scaffold or recellularized matrixes

Sicilia Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


Pagina 123 di 231



SCORE.


STRATEGICA

RF‐2011‐02349547

Early integration of palliative care with standard oncologic care in advanced non‐

small cell lung cancer. A prospective,multi‐center observational study to evaluate how this approach impact on patients survival and quality of life with an additional anal

Veneto Clinical Healthcare Delivery and Methodologies

16,75Oncology

RF‐2011‐02349435

Fostering donation: from bench to culture MAGGIORE Clinical Healthcare Delivery and Methodologies


RF‐2011‐02347696

HUMAN ADIPOSE STEM CELLS AS A NOVEL TARGET FOR THERAPEUTIC INTERVENTION IN OBESITY



RF‐2011‐02349433

Innovative aspects in the study of acute hepatitis C, in the laboratory diagnosis and study of clinica, genetic, virological and biomolecular prognostic markers and in the optimization of therapeutic protocols

Campania Biomedical Infectious Diseases and Microbiology


RF‐2011‐02348328

MICRORNA IN THYROID CARCINOMA: PATHWAYS INVOLVED AND POSSIBLE PROGNOSTIC AND THERAPEUTIC IMPACT


RF‐2011‐02351427

A CLINICAL AND MORPHOLOGICAL INVESTIGATION OF BOTULINUM TOXIN‐A TREATMENT FOR NEUROGENIC DETRUSOR OVERACTIVITY: OUTCOMES, CORRELATION BETWEEN URODYNAMIC PATTERN AND EXPRESSION OF UROTHELIUM AND SUBUROTHELIUM ION CHANNELS AND NEUROKININ RECEPTORS IN SPINA

Toscana Biomedical Digestive, Kidney and Urological Systems


Pagina 124 di 231



SCORE.


STRATEGICA

RF‐2011‐02349218

Standardization of a SNP‐typing protocol for epidemiology of Listeria monocytogenes and study of the molecular evolution of an emerging Epidemic Clone.

IZS Puglia e della Basilicata Biomedical Infectious Diseases and Microbiology


RF‐2011‐02348701

Epidemiological, clinical and molecular aspects of Environmental Intolerance Disorders with Difficult Diagnosis in the Italian population, with special focus on the sick worker. Implications for Disease Definition, Diagnosis and Treatment, and Workplace S

IDI Biomedical Immunology 17Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02352873

PERFUSION COMPUTED TOMOGRAPHY (PCT) AND VASCULAR ENDOTHELIAL GROWTH FACTOR‐A (VEGF‐A) SERUM AND LIQUOR LEVELS IN THE MANAGEMENT OF HIGH GRADE GLIOMAS

NEUROMED Clinical Emerging Technologies and Training in Neurosciences

17Oncology

RF‐2011‐02351734

Instrumental and clinical validation of a new diagnostic‐therapeutic approach to the dysfunction of movement for rehabilitation in non‐specific low back pain

Emilia‐Romagna Clinical Bioengineering Sciences and Technologies


RF‐2011‐02350855

Development and validation of software tools to use radiation dose data extracted from digital medical images for radiation protection purposes

I. O. V. Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering

17Oncology

RF‐2011‐02351666

Sleep disorders in neuromuscular diseases: a comprehensive clinical and polisomnographyc study regarding myotonic dystrophies type 1 and type 2 and spinal bulbar muscular atrophy (SBMA).



Pagina 125 di 231



SCORE.


STRATEGICA

RF‐2011‐02351663

Clinical Impact of Image guided hypofractionated intensity modulated radiotherapy in the treatment of prostate, lung and head and neck cancers


RF‐2011‐02352825

Definition of a "Myeloma Panel" to analyze the role played by clonal evolution in the resistance to therapy


RF‐2011‐02346802

A translational integrated study on prostate diseases and environmental risk factors in Sicily for primary and secondary prevention (acronym: PROSTENV)



RF‐2011‐02352776

Risk assessment of developing atypical Hemolitic Uremic Syndrome by genetic and epigenetic investigations

MAGGIORE Biomedical Genes, Genomes and Genetics 17Infection and immunity

RF‐2011‐02349077

IDENTIFICATION OF NEW DRUGGABLE PATHWAYS FOR PERSONALIZED TREATMENTS IN INTRAHEPATIC CHOLANGIOCARCINOMA


RF‐2011‐02350723

Preclinical Development of Novel Small Androgen Receptor Modulating Molecules (SARMs) in Experimental Human Prostate Cancer Model.

IRST Meldola Biomedical Oncology 2 ‐ Translational Clinical 17Oncology

RF‐2011‐02349224

Role of Vitamin D receptor in angiogenic and DNA damage repair pathways with respect to BRCA1 status

ONCOLOGICO DI BARI Biomedical Oncology 2 ‐ Translational Clinical 17Oncology

Pagina 126 di 231



SCORE.


STRATEGICA

RF‐2011‐02352728

Internet Addiction in adolescents: identification of possible neurobiological and personality markers.



RF‐2011‐02350996

Perturbed hydrogen sulphide content in Amyotrophic Lateral Sclerosis: a possible player in motor neurons degeneration?



RF‐2011‐02350641

Assessment of Predictive Biomarkers of Outcome and Treatment Response in Primary Tumor and in Circulating Tumor Cells of Non‐Small Cell Lung Cancer Patients by Organization of a Clinical and Molecular Network in Sicily

Sicilia Clinical Oncology 2 ‐ Translational Clinical 17Oncology

RF‐2011‐02349202

The molecular basis of the interplay between leukotriene and purinergic systems: new therapies in vascular inflammation



RF‐2011‐02350468

Causes, diagnosis and treatment of unexplained neurobehavioral disorders: role of thyroid hormone cell membrane transporters and environmental contaminants.

Toscana Biomedical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02348614

Innovative preclinical platforms for the personalized treatment in ovarian cancer


Pagina 127 di 231



SCORE.


STRATEGICA

RF‐2011‐02352657

Multi‐Step versus Single‐Step strategy of Transjugular Intrahepatic Portosystemic Shunt (TIPS) Endoprosthesis Placement for Prevention of Post‐TIPS Hepatic Encephalopathy in Cirrhotic Patients with Refractory Ascites.



RF‐2011‐02348599

Traditional and innovative monitoring of dioxins and dioxin like‐compounds in exposed sheep: chemical and biomolecular approaches in a sentinel species.



RF‐2011‐02349272

DEVELOPMENT OF 3D IN VITRO TUMOUR/MSC COCULTURE MODEL AND IN VIVO IMAGING LUMINESCENT PROTOCOL TO REFINE AND REDUCE THE USE OF ANIMAL IN ONCOLOGICAL STUDIES. (DIANA)

IZS Lombardia e dell'Emilia Biomedical Veterinary 17Food safety and animal welfare

RF‐2011‐02351467

Facioscapulohumeral muscular dystrophy: to define non‐invasive outcome measures and elucidate molecular mechanisms underlying muscle degeneration by means of longitudinal muscle MRI studies, immunological assessment and biomolecular characterization of a

MONDINO Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02349333

LAV‐ BPIFB4 isoform, a new target to fight endothelial dysfunction

MULTIMEDICA Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02352602

Early Neurorehabilitation in Neurosubintensive Care Unit

Lombardia Clinical Brain Disorders and Clinical Neuroscience


Pagina 128 di 231



SCORE.


STRATEGICA

RF‐2011‐02348461

Development of novel chemo‐immunotherapy strategy for hepatocellular carcinoma


RF‐2011‐02348746

Nanoparticles engineered with antibody derivatives or other molecules recognizing markers overexpressed in breast cancer cells for metastatic tumor detection

Lombardia Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering

17Oncology

RF‐2011‐02350290

Impact of intensive follow up on diagnostic anticipation in high risk stage I‐III breast cancer patients. A phase II, multicenter randomized study.


Clinical Oncology 2 ‐ Translational Clinical 17Oncology

RF‐2011‐02349827

From bench to bedside in deciphering the modulatory mechanisms of the molecular damage in hereditary spastic paraplegias



RF‐2011‐02348109

Developing an event‐based computational model of Alzheimer's disease progression incorporating quantitative MRI and TMS information to assist clinicians in the early diagnosis, correct prognosis, and treatment monitoring.



RF‐2011‐02351305

Compound Seropositivity of neutralizing antibodies against Adipogenic Adenoviruses (ADV36+ and ADV 37+): effect of nutritional intervention on overweight‐obesity, Non‐Alcoholic‐Fatty‐Liver‐Disease (NAFLD) and on Insulin Resistance.

Sicilia Biomedical Digestive, Kidney and Urological Systems


Pagina 129 di 231



SCORE.


STRATEGICA

RF‐2011‐02352074

Estimate of Late diagnosis and Late presentation of HCV infection in high‐risk and hard to reach population.



RF‐2011‐02347467

The Rac1‐activator CNF1 as a therapeutic approach for amyotrophic lateral sclerosis



RF‐2011‐02347859

Isolated Hemihyperplasia (IH), a pediatric cancer risk disease: search for novel genes and mechanisms

AUXOLOGICO Biomedical Genes, Genomes and Genetics 17The new biotechnologies

RF‐2011‐02347589

Apoptotic and DNA damage/repair mechanisms induced by anti‐neoplastic agents in mammalian oocytes of the ovarian reserve and strategies for fertility preservation in female patients.


17Oncology

RF‐2011‐02352327

Monitoring infection in complex wounds in pediatric patients


Clinical Healthcare Delivery and Methodologies


RF‐2011‐02349690

EXOSOME‐MEDIATED CONTROL OF HEMATO‐ENDOTHELIAL CELL DIFFERENTIATION

ISS Biomedical Cell Biology 17Oncology

RF‐2011‐02351157

ROLE OF DORSOLATERAL PREFRONTAL CORTEX IN LONG TERM RECOGNITION MEMORY: TRANSCRANIAL MAGNETIC STIMULATION APPROACHES FOR TREATMENT OF LONG TERM MEMORY DEFICITS IN AMNESIC PATIENTS



RF‐2011‐02350125

Identifcation of the genetic landscape of T‐cell lymphoblastic lymphoma of childhood

Veneto Biomedical Oncology 1 ‐ Basic Translational 17Oncology

Pagina 130 di 231



SCORE.


STRATEGICA

RF‐2011‐02348221

STRUCTURED PATHOLOGICAL REPORT IN ONCOLOGY.A DIGITAL NETWORK

AMONG PATHOLOGY UNITS, TUMOR REGISTRIES AND REGIONAL HEALTH CARE SYSTEM.


17Oncology

RF‐2011‐02349872

CDKL5 DISORDER: identification of the molecular mechanisms underlying the neurological phenotype




RF‐2011‐02349730

New molecular predictive markers in Colorectal Cancer (CRC)

Sicilia Biomedical Genes, Genomes and Genetics 17Oncology

RF‐2011‐02347597

Exploiting the diagnostic, prognostic and therapeutic potential of microRNAs in melanoma

IDI Biomedical Oncology 2 ‐ Translational Clinical 17Oncology

RF‐2011‐02351405

BIOSAFETY OF HUMAN MESENCHYMAL STEM CELLS: GENOMIC AND MEMBRANE STABILITY FOR A BETTER CLINICAL APPROACH

Piemonte Biomedical Genes, Genomes and Genetics 17The new biotechnologies

RF‐2011‐02351065

Development of guidelines for the management of cluster of cancer and other diseases in areas with environmental criticalities and translation for public health decision‐makers.

Toscana Clinical Population Sciences and Epidemiology


RF‐2011‐02350056

Artificial Neural Network in development of Innovative Diagnostic systems for Atherosclerotic disease (The ANN‐IDA project)

MONZINO Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


Pagina 131 di 231



SCORE.


STRATEGICA

RF‐2011‐02349548

Atherogen Genetic Dyslipidemias (AGD): are they missed diseases?Estimate of

frequency of AGD diagnoses in the Tuscany hospitals and strategy design to identify probands with AGD and trigger early diagnosis in family members



RF‐2011‐02348081

Genetic and pharmacological inhibitors of the Epithelial‐Mesenchymal Transition

REGINA ELENA Biomedical Oncology 1 ‐ Basic Translational 17Oncology

RF‐2011‐02347950

Role of adipose derived stem cells in chondrocyte functional impairment in metabolic osteoarthritis



RF‐2011‐02347580

A new therapeutic approach against HPV cancer based on anti‐E6 and ‐E7 scFv antibodies: validation in preclinical models and studies on the molecular mechanisms

ISS Biomedical Oncology 2 ‐ Translational Clinical 17The new biotechnologies

RF‐2011‐02350289

Metabolic tumour volume as assessed by 18F‐FDG PET/CT for tailoring therapy in patients with locally advanced rectal cancer candidate for neoadjuvant chemoradiation.

Liguria Clinical Oncology 2 ‐ Translational Clinical 17Oncology

RF‐2011‐02351026

Chemotherapies of stem‐cells‐based solid vascularized tumors: from the bench to the bedside passing through equations

I.E.O. Biomedical Bioengineering Sciences and Technologies

17,25Oncology

RF‐2011‐02350009

Effect of lower limb end‐effector robot‐assisted therapy with Virtual Realty on gait training in Parkinson Patients.




Pagina 132 di 231



SCORE.


STRATEGICA

RF‐2011‐02351820

Forced Robotic Exercise Training effects on motor and cognitive functions of Parkinson's Disease patients

Toscana Biomedical Emerging Technologies and Training in Neurosciences


RF‐2011‐02350955

Neurocognitive deficits related to cardiosurgery intervention with extracorporeal circulation. Correlations between neuropsychological performances and functional MRI techniques (Spectroscopy, Diffusion and Morphometry)



RF‐2011‐02349353

Postactivation depression in hemiplegic stroke survivors: implications for assessment and treatment of spasticity




RF‐2011‐02348790

Culture and characterization of oral mucosal and conjunctival epithelial stem cells for the reconstruction of the ocular surface in patients with bilateral limbal stem cell deficiency



RF‐2011‐02350884

RESPIRATORY TRAINING IN HEART FAILURE: A NON‐INVASIVE METHOD TO INCREASE THE CHOLINERGIC ANTI‐INFLAMMATORY PATHWAY

MAUGERI Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02351872

Evaluation of in vitro drug‐sensitivity and phosphoproteomic expression profiles in patients diagnosed with renal carcinoma

REGINA ELENA Clinical Digestive, Kidney and Urological Systems

17,5Oncology

RF‐2011‐02349256

Nanomaterials and Health: a multilevel approach to study the effects of nanomaterials at workplaces

INAIL Biomedical Bioengineering Sciences and Technologies


Pagina 133 di 231



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STRATEGICA

RF‐2011‐02349479

Identification of biological and immune correlates of therapeutic responses for HPV‐positive epithelial cancers: an ex vivo organotypic multi‐cellular model for patient‐tailored therapies.


RF‐2011‐02352224

Signals from deregulated skin metabolism control generalized metabolic syndrome in psoriasis

IDI Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02350703

In vitro assessment of lactic acid bacteria for suitability as probiotics in calves to improve health in newborns and to contrast neonatal mortality


RF‐2011‐02349790

Role of DNA‐PK in neurodegeneration and aging: enhancement of DNA repair as novel therapeutic approach



RF‐2011‐02349213

Genomics of treatment response in acute myeloid leukemia

I.E.O. Biomedical Oncology 2 ‐ Translational Clinical 17,5Oncology

RF‐2011‐02350704

IS IT TIME TO SELECT PATIENTS WITH MALIGNANT PLEURAL MESOTHELIOMA (MPM) WHO MIGHT BENEFIT FROM AGGRESSIVE TREATMENT AND PROSPECTIVELY ANALYZE ONCOLOGIC AND FUNCTIONAL RESULTS?



RF‐2011‐02349843

SEPSIS TEAM: A MODEL OF INNOVATIVE MANAGEMENT OF THE PATIENT REFERRED TO EMERGENCY DEPARTMENT WITH A CONDITION OF SEVERE SEPSIS/SEPTIC SHOCK

Emilia‐Romagna Clinical Infectious Diseases and Microbiology


Pagina 134 di 231



SCORE.


STRATEGICA

RF‐2011‐02351784

Endogenous obesogens accumulation and adipose tissue dysfunction: identification of toxogenomic, metabolomic and epigenetic signatures in adipocytes as a tool to understand environmental causes of human obesity

AUXOLOGICO Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02346995

Radiation exposure optimization by wireless technology for professionals involved in the management and care of patients undergoing therapy with radionuclides. Implementation of environmental monitoring.

CROB Clinical Healthcare Delivery and Methodologies


RF‐2011‐02351612

Molecular basis of Treatment‐Resistant Depression



RF‐2011‐02352098

Molecular events underlying the metastatic potential of cancer stem cells

Sicilia Biomedical Oncology 2 ‐ Translational Clinical 17,5Oncology

RF‐2011‐02351127

IDENTIFICATION OF NEW STRATEGIES TO IMPROVE THE OUTCOME OF TRAUMATIC BRAIN INJURY AND BRAIN ISCHEMIA: PRECLINICAL AND CLINICAL STUDIES ON NEW TARGETS AND ALREADY CLINICALLY AVAILABLE DRUGS

Sicilia Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349188

Evaluation of the olfactory function in the endoscopic trans‐nasal neurosurgical cancer patients: advanced medical technology and methodology




Pagina 135 di 231



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STRATEGICA

RF‐2011‐02352209

Morphological and molecular phenotype of lung cancer in chronic obstructive pulmonary disease


RF‐2011‐02347140

Pathogenesis, diagnosis and course of familial and sporadic Alzheimer¿s disease and Frontotemporal Lobar degeneration: epigenetics and proteomics as new tools for disease mechanisms and biomarker discovery



RF‐2011‐02348036

Identification of genetic variants associated with appropriate ICD therapy




RF‐2011‐02347676

Novel PHOX2B defects and additional genes involved in the onset of Respiratory and Autonomic Disorders in Infancy, Childhood and Adulthood (RADICA): definition of pathogenic mechanisms and search for ameliorative drugs

GASLINI Biomedical Genes, Genomes and Genetics 17,5Neurological diseases

RF‐2011‐02351936

Determination of the dose distribution in patients treated with high energy photon beams using transmitted dose planar distributions measured with a new gas detector technology (Gas Electron Multipliers) and a dedicated back‐projection algorithm.

REGINA ELENA Biomedical Oncology 2 ‐ Translational Clinical 17,5Oncology

RF‐2011‐02351051

Neonatal development, neuro‐endocrine programming and mother‐child exposure to pesticides: a translational prevention study (NATAL)



Pagina 136 di 231



SCORE.


STRATEGICA

RF‐2011‐02350387

Role of microRNAs in esophageal carcinogenesis and the possible correlation between microRNA serum levels and different stages of esophageal disease

Sicilia Biomedical Oncology 1 ‐ Basic Translational 17,5Oncology

RF‐2011‐02347670

Active music therapy approach in the rehabilitation of stroke: a randomized controlled trial.

MAUGERI Clinical Healthcare Delivery and Methodologies


RF‐2011‐02352705

Study and modelling of early alterations of microcirculation insepsis aimed at

personalized treatment and identification of the outcome.

Toscana Clinical Infectious Diseases and Microbiology


RF‐2011‐02349636

Characterization of specific factors that prevent HIV‐1‐induced cell death in Long Term Non Progressors and Elite Controllers. From pathogenesis to new treatments.


RF‐2011‐02350773

Immunologic, autonomic and metabolic components of exercise medicine in cancer survivors

HUMANITAS Clinical Risk, Prevention and Health Behavior

17,5Oncology

RF‐2011‐02348231

Respiratory Syncytial Virus (RSV) infection in infants: the IFNs/ Ectonet axis as possible therapeutic target.


RF‐2011‐02352554

Melanoma: from next generation sequencing to personalized targeted therapy

SAN GALLICANO Clinical Healthcare Delivery and Methodologies

17,5Oncology

Pagina 137 di 231



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STRATEGICA

RF‐2011‐02349148

Age‐related evaluation of the usefulness of implantable cardiac defibrillator with or without cardiac resynchronization therapy: a real‐world analysis in patients with severe chronic heart failure



RF‐2011‐02347299

Pathophysiology of obesity‐related vascular dysfunction: comparison between "metabolically healthy obesity" and the metabolic syndrome



RF‐2011‐02352508

Circulating biomarkers as predictive and prognostic factors in patients with stage III melanoma: analysis of circulating melanoma cells (CMCs), circulating free‐DNA (cfDNA) and molecular characterization of BRAF and NRAS mutational status in primary tumor

Lombardia Biomedical Oncology 2 ‐ Translational Clinical 17,5Oncology

RF‐2011‐02350812

Single‐dose intravenous iron in patients with functional iron deficiency after acute myocardial infarction: impact on hospital‐acquired anemia, cardiovascular and functional status

AUXOLOGICO Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02350075

A wait and see approach to identify predictors of aggressiveness in sporadic desmoid tumor


RF‐2011‐02351044

Origin and significance of residual viremia in virologically suppressed HIV‐infected patients.


Pagina 138 di 231



SCORE.


STRATEGICA

RF‐2011‐02348267

Unraveling the molecular basis of neurodegeneration in frontotemporal lobar degeneration: role of genome instability associated with tau mutations



RF‐2011‐02347320

PROTEASE VARIABILITY IN PATIENTS INFECTED WITH HEPATITIS C VIRUS

GENOTYPE 1: IMPLICATIONFOR ANTIVIRAL TREATMENT USING DIRECTLY ACTING ANTIVIRALS (DAA)



RF‐2011‐02351905

Evaluation of the pathogenetic role of Parvovirus B19V in systemic sclerosis and autoimmune thyroiditis.

Toscana Clinical Immunology 17,5Infection and immunity

RF‐2011‐02351461

Evaluation of the activity of HIV protease or reverse transcriptase inhibitors against experimental models of uterine cervical tumours


RF‐2011‐02352604

Investigating the relationship between animal farming and antibiotic resistances in natural or environmental prokaryotic communities


RF‐2011‐02349701

CDKs blockade for molecular targeting in human cancer.


RF‐2011‐02352438

ANALYSIS OF THE GENETIC AND EPIGENETIC BASIS OF HCV‐RELATED LYMPHOPROLIFERATIVE DISORDERS


17,5Oncology

Pagina 139 di 231



SCORE.


STRATEGICA

RF‐2011‐02351320

Determinants of functional recovery in elderly hip fracture subjects admitted to orthogeriatric units: a multicentre observational study


Clinical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02351367

MicroRNA: new markers for the diagnosis of occult hepatitis B



RF‐2011‐02348167

NAFLD (Non‐Alcoholic Fatty Liver Disease) : which relationship of liver steatosis and concurrent fibrosis with heart function.



RF‐2011‐02348429

Ageing at work: promoting health and safety of ageing workers according to

changes of demography, labourmarket and social policies.

MAGGIORE Biomedical Risk, Prevention and Health Behavior


RF‐2011‐02349429

In vivo identification of molecular determinants critical to the metastatic process in melanoma.


RF‐2011‐02347250

Vitamin D as a disease modulator in multiple sclerosis: immunomodulatory activity on antigen presenting cell and gamma/delta T lymphocytes and regulation of their cross‐talk

ISS Biomedical Immunology 17,5Neurological diseases

RF‐2011‐02348860

The potential of the SRCIN1/p140Cap gene as prognostic risk factor and tumor suppressor in neuroblastoma

GASLINI Biomedical Oncology 1 ‐ Basic Translational 17,5Oncology

Pagina 140 di 231



SCORE.


STRATEGICA

RF‐2011‐02347668

Oxidative stress in animal cancer stem cells: biological mechanisms involved in the pathogenesis of mammary spontaneous tumors



RF‐2011‐02349935

HIV eradication: pharmacological modulation of HIV latent reservoir by targeting of sirtuin family of de‐acetylating enzymes

Sicilia Biomedical AIDS and Related Research 17,5Infection and immunity

RF‐2011‐02347252

Targeting endothelin‐1/ß‐arrestin signaling to circumvent chemoresistance in epithelial ovarian cancer


RF‐2011‐02351932

Behavioural and neurophysiological aspects of communicative‐pragmatic abilities in healthy individuals and pathological conditions: assessment and rehabilitation



RF‐2011‐02348350

Treatment of advanced or recurrent endometrial cancer: identification of molecular predictors of response in a randomized phase II study with Bevacizumab in combination to Carboplatin‐Paclitaxel


RF‐2011‐02348683

Multimodal nanotechnological approach against hepatocellular carcinoma: Sorafenib loaded magnetic nanoparticles for targeted chemotherapy and localized hyperthermia.


Pagina 141 di 231



SCORE.


STRATEGICA

RF‐2011‐02349144

Identification and biomolecular characterization of circulating tumor cells from patients with ovarian epithelial cancer using tumor‐specific fluorescent ligands: A new in vivo non‐invasive method.


RF‐2011‐02349830

Pathophysiological approach to the interventional therapy of limb atherosclerotic disease ‐ A biomedical, mechanistic study

Emilia‐Romagna Biomedical Vascular and Hematology 18Metabolism disorders and cardiovascular disease

RF‐2011‐02349231

DEVELOPMENT OF ADVANCED NANOTECHNOLOGIES FOR EARLY ALZHEIMER DIAGNOSIS: FROM THE SYNTHESIS TO THE CLINICAL VALIDATION

Puglia Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02351195

The activation of vestibular system as a possible tool for inducing analgesia, speeding up recovery from stroke and facilitating recovery from vegetative and minimal conscious state



RF‐2011‐02348945

Development of innovative compounds for the treatment of renal cell carcinoma

Abruzzo Biomedical Oncology 2 ‐ Translational Clinical 18Oncology

RF‐2011‐02350807

Safety of workers with implanted medical devices in MRI environment: criteriafor

occupational risk evaluation

ISS Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02352293

DENOSUMAB FOR THE TREATMENT OF SYSTEMIC SCLEROSIS RELATED OSTEOPOROSIS: AN OPEN‐LABEL PILOT SAFETY STUDY.

Basilicata Clinical Musculoskeletal, Oral and Skin Sciences


Pagina 142 di 231



SCORE.


STRATEGICA

RF‐2011‐02352264

Epigenetic change in DNA structure may serve as marker for neurological disease

Marche Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02347774

Therapeutic strategies in refractory chronic daily headache: A multicenter, randomized, controlled trial.


Clinical Emerging Technologies and Training in Neurosciences


RF‐2011‐02352259

Occupational and non‐occupational risk factors for retinal detachment: a multicentre population‐based case‐control

study

Emilia‐Romagna Biomedical Population Sciences and Epidemiology


RF‐2011‐02346859

Memory training with transcranial direct current stimulation (tDCS) and cognitive reserve in Multiple Sclerosis and Alzheimer disease. A longitudinal clinical and MRI study

Lombardia Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02351259

Pre‐eclampsia: the role of genetics in understanding the etiopathogenesis and evaluation of early predictive biomarkers



RF‐2011‐02350698

Development of functionalized magnetic nanoparticles (VIVIT‐MNP) for IBD treatment: possible involvement of NFAT transcription factor

Lombardia Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02349911

Impact of JC and BK polyomaviruses infection on human infertility and recurrent pregnancy loss



Pagina 143 di 231



SCORE.


STRATEGICA

RF‐2011‐02346963

Role of GALNT2 on glucose homeostasis. A multidisciplinary approach including cell biology, animal and human studies.




RF‐2011‐02351153

A genomic and proteomic approach to explore phenotype variability in Gerstmann‐Sträussler‐Scheinker syndrome (GSS) linked to P102L mutation in the PRNP gene



RF‐2011‐02349087

Oleuropein aglycone can be effective against AD in humans. A clinical trial



RF‐2011‐02352234

Non‐Invasive Monitoring of Circadian Rhythm Disorders In Shift‐workers

I.N.R.C.A. Clinical Biobehavioral and Behavioral Processes


RF‐2011‐02350185

Identification and protein profiling of extracellular vesicles in the cerebrospinal fluid of patients with Mild Cognitive Impairment and Alzheimer¿s disease: a new potential diagnostic tool



RF‐2011‐02348872

The role coagulation/complement upregulation and neurotropic viral activation play in Multiple Sclerosis

REGINA ELENA Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02348718

Telomere‐targeting agents: Towards clinical candidates selections


RF‐2011‐02352789

Study of molecular based approach for the epidemiological characterization of strains of Listeria monocytogenes isolated in food and human cases in Italy

IZS Abruzzo e del Molise Biomedical Veterinary 18Food safety and animal welfare

Pagina 144 di 231



SCORE.


STRATEGICA

RF‐2011‐02351926

High resolution molecular cytogenetics in colorectal cancer and oral premalignant

lesions.

Sicilia Biomedical Oncology 1 ‐ Basic Translational 18Oncology

RF‐2011‐02352337

Chemoprevention of radiation damages induced by radiodiagnostic procedures

REGINA ELENA Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering

18Oncology

RF‐2011‐02350573

Organic pollutant and plastic‐associated chemical effects on cardiovascular diseases: a sex‐gender issue



RF‐2011‐02347143

Cockayne syndrome: the role of bioenergetics dysfunction in neurodegeneration and design of new therapeutic approaches



RF‐2011‐02350671

Cancer and adolescence: what clinical and sociological approach? A preliminary project in Italy

C.R.O. AVIANO Clinical Healthcare Delivery and Methodologies

18Oncology

RF‐2011‐02351058

New targets for therapy in breast cancer: dietary induced inhibition of mammalian target of rapamycin (mTOR)

SDN Biomedical Oncology 2 ‐ Translational Clinical 18Oncology

RF‐2011‐02351357

Inhibition of the Hedgehog Signaling Pathway for the Treatment of Patients with Osteosarcoma


Pagina 145 di 231



SCORE.


STRATEGICA

RF‐2011‐02348168

OBESITY AND DIABETES/HYPERTENSION RISK IN CHILDREN: PREVENTION AND TREATMENT THROUGH MONITORED PHYSICAL ACTIVITY and NUTRITION PROGRAMS


Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02349703

Lipoprotein(a) and soluble lectin‐like oxidized LDL receptor‐1 (sLOX‐1) as a potential causal genetic risk factor for atherosclerosis in a prospective population‐based study (PLIC study)


RF‐2011‐02347102

Liver targeted cell therapy: applications to experimental Glycogen Storage Disease type 1a

GASLINI Biomedical Genes, Genomes and Genetics 18Metabolism disorders and cardiovascular disease

RF‐2011‐02349684

Food Safety: protection of the public health through the determination of some endocrine disruptors in water and foods of large consumption

IZS Mezzogiorno Biomedical Veterinary 18Food safety and animal welfare

RF‐2011‐02348553

IS THERE A "SMELLING SIDE" IN THE HUMAN MOTOR SYSTEM? Towards a clinical relevance of olfacto‐motor cross‐modal intercations



RF‐2011‐02349679

Counteracting oxidative stress in Rett syndrome



RF‐2011‐02348388

Mechanism of action and in vivo efficacy of anti‐inflammatory treatments in Treg induction, regulation of neuroinflammation and arrest of dementia progression.

NEUROLESI Biomedical Brain Disorders and Clinical Neuroscience


Pagina 146 di 231



SCORE.


STRATEGICA

RF‐2011‐02347898

Cystic Lesions of the Pancreas: Creation of a Database and a New Evidence‐Based, CostEffective Algorithm


18Oncology

RF‐2011‐02350409

PYB ‐ Protect Your Back (Effectiveness of Back Protector in preventing spinal cord injuries)



RF‐2011‐02352285

Early discharge from the emergency department of nursing‐home dwelling older patients with community acquired pneumonia in comparison to normal hospitalization: a randomized clinical trial



RF‐2011‐02352004

A novel TRAIL‐based therapeutic by mesenchymal cells TARgeting PAncreatic Cancer (TARPAC)


RF‐2011‐02351410

Nuclear Signaling Mediated by the Innate Immune/Inflammtory Kinase PKR as a Therapeutic Target and Prognostic Indicator of Disease Progression and Therapeutic Response in Myelodysplastic Syndromes and Acute Leukemia

RIZZOLI Biomedical Vascular and Hematology 18Oncology

RF‐2011‐02349551

EXOME SEQUENCING BASED DETECTION OF VARIANTS RELEVANT TO THE CLINICAL SPECTRUM OF NEONATAL BRONCHO PULMONARY DYSPLASIA AND RESPIRATORY DISTRESS

SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 18The new biotechnologies

Pagina 147 di 231



SCORE.


STRATEGICA

RF‐2011‐02351462

Biological endophenotypes associated to the electroconvulsive therapy in treatment resistant depression.


Biomedical Biobehavioral and Behavioral Processes


RF‐2011‐02349793

Correlation between estrogen depletion and Alzheimer¿s disease: analysis of gene expression and brain functions in humans and animal models

OASI MARIA S.S. Biomedical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02351843

Reduction of atrial fibrillation and stroke in systemic arterial hypertension: a randomized control trial comparing routine medical treatment versus primary care physicians guided drug regiment delivery through intensive blood pressure

monitoring

SAN DONATO Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02348165

Development of a multi‐stage vaccine against tuberculosis

Veneto Biomedical Immunology 18Infection and immunity

RF‐2011‐02346978

Improving radiotherapy of high grade gliomas by Ataxia Telangiectasia Mutated protein inhibition



18Oncology

RF‐2011‐02348623

Implementation of the Montreal Cognitive Assessment as a standard neuropsychological screening tool in Italian stroke units



Pagina 148 di 231



SCORE.


STRATEGICA

RF‐2011‐02350636

Occupational Mycobacterium tuberculosis infection among healthcare workers: assessing the burden and developing modern strategies for risk assessment and health surveillance

SPALLANZANI Clinical Population Sciences and Epidemiology


RF‐2011‐02352708

Study of new biomarkers for diagnoses of disorders of bile acid synthesis by mass spectrometry and metabolomics approach

Veneto Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02347562

CLINICAL RELEVANCE OF IMMUNE RESPONSES TO PROPHYLACTIC HPV VACCINE IN ITALY: A NATIONAL IMMUNOMONITORING NETWORK


RF‐2011‐02351838

Study on the use of vodcast in the treatment of Anorexia Nervosa

Veneto Clinical Biobehavioral and Behavioral Processes


RF‐2011‐02350928

Genetic polymorphisms in genes of drug‐related and DNA repair pathways as predictive markers of the therapeutic efficacy in esophageal carcinoma

I. O. V. Biomedical Oncology 2 ‐ Translational Clinical 18Oncology

RF‐2011‐02349249

The early identification of newborns at high risk of brain injury: the role of oxidative stress.



RF‐2011‐02350302

Translational value of pathophysiological pathways and therapeutic agents on lipid dysmetabolism in the hepatobiliary and cardiovascular system: a bench‐to‐bedside project.

Puglia Biomedical Healthcare Delivery and Methodologies


Pagina 149 di 231



SCORE.


STRATEGICA

RF‐2011‐02349259

Two innovative rapid screening methods of corticosteroids as growth‐promoters in cattles using MEAs and an enhanced histopathological approach



RF‐2011‐02351554

Mechanisms of extracranial organ damage after acute brain injury: role of protective mechanical ventilation in reducing incidence of acute respiratory distress syndrome and attenuating systemic inflammation in acute neurologically ill patients



RF‐2011‐02347029

Treatment of Subsyndromal Delirum (SSD) and long term Cognitive Dysfunction after Cardiac Surgery. Evaluation of possible neural mechanism underlyning Delirium

Emilia‐Romagna Clinical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02347598

Impact of HIV on the pathogenesis of Mycobacterium tuberculosis: autophagy involvement and new pharmacological target



RF‐2011‐02350852

Phase I/II clinical trial of dendritic cell therapy for the treatment of metastatic melanoma based on an innovative way to generate a whole repertoire of tumor peptides via gap junction pores


RF‐2011‐02351978

THROMBOTIC MARKERS AS INNOVATIVE TOOLS FOR CANCER PROGNOSIS IN ONCOLOGICAL PATIENTS UNDERGOING HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY

Lombardia Biomedical Oncology 2 ‐ Translational Clinical 18,25Oncology

Pagina 150 di 231



SCORE.


STRATEGICA

RF‐2011‐02348646

EFFECTS OF BLUNTING DAILY GLUCOSE FLUCTUATIONS ON COGNITIVE PERFORMANCE IN AGED TYPE 2 DIABETIC PATIENTS



RF‐2011‐02351994

FUNCTIONAL PROFILING OF MONOCYTE/MACROPHAGE POPULATIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA: INVOLVEMENT IN CLINICAL OUTCOME


RF‐2011‐02351975

Daily monitoring of pediatric asthmatic outpatients: environment and health relationship.




RF‐2011‐02348324

Cellular autoimmunity and causative autoantigens in acquired thrombotic thrombocytopenic purpura (TTP)

MAGGIORE Biomedical Immunology 18,5Infection and immunity

RF‐2011‐02348270

Exploiting cellular transcription factors of the Interferon Regulatory Factors family in novel therapeutic approaches to HIV‐1 infection and reactivation from latency


RF‐2011‐02352310

Systemic and local characterization of clinical remission in rheumatoid arthritis patients treated with biologic agents: predictors, dynamics and pathologic stability.

SAN MATTEO Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02352084

Human Cardiac Stem Cell Regenerative Capacity in Paediatric Heart Failure

Lazio Biomedical Cardiovascular and Respiratory Sciences


Pagina 151 di 231



SCORE.


STRATEGICA

RF‐2011‐02352085

Genetic and Antigenic Evolution of West Nile virus Isolated in Italy and Characterization of Viral‐Host Mechanisms Regulating Infection and Pathogenesis


RF‐2011‐02351746

RISK OF INFECTION IN RHEUMATOID ARTHRITIS (RA): INVOLVEMENT OF INNATE IMMUNITY AND BIOLOGIC THERAPIES.

Campania Biomedical Immunology 18,5Infection and immunity

RF‐2011‐02348856

Superpolyps: superantigen‐induced T‐ and B‐cell accumulation in nasal polyps



RF‐2011‐02348593

Biomolecular serological and epidemiological investigations on Encefalomyocarditis virus and his zoonotic roles in Italy.


RF‐2011‐02347791

Development and implementation of a protocol for communication of genetic information and multidisciplinary genetic counseling in ALS, in parallel with identification of early alterations in pre‐symptomatic ALS.

Piemonte Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02352587

PREDICTION OF AWAKENING FROM ACUTE COMA, USING THE BRAIN REACTIVITY TO PAIN‐RELATED‐SOMATOSENSORY EVOKED POTENTIALS.



Pagina 152 di 231



SCORE.


STRATEGICA

RF‐2011‐02352590

microRNAs and Single Nucleotide Polymorphisms as potential screening biomarkers for early detection of colorectal cancer.


RF‐2011‐02351805

Appropriateness of systemic anticancer therapy in advanced cancer patients: the use of AIFA monitored antineoplastic drugs in the end of life in Regione Emilia‐Romagna


18,5Oncology

RF‐2011‐02347999

A Web Intelligence approach to the patient empowerment: exploring knowledge on internet conversations


18,5Oncology

RF‐2011‐02347865

New insights for Attention Deficit and Hyperactivity Disorder (ADHD): novel serotonin 7 receptor agonist drugs for putative therapy, and clinical validation of the circulating auto‐Antibodies against DAT as a bio‐marker for diagnosis.



RF‐2011‐02347870

miRNA in the blood as biomarkers and therapeutic indicators of progressive tissue degeneration in Glycogen Storage Disease type 1a patients

GASLINI Biomedical Genes, Genomes and Genetics 18,5Metabolism disorders and cardiovascular disease

RF‐2011‐02346883

Expression of indoleamine 2,3‐dioxygenase 1 (IDO1) in childhood acute leukemia: mechanisms of induction/regulation and clinical implications for leukemia control and patient survival.


Biomedical Immunology 18,5Oncology

Pagina 153 di 231



SCORE.


STRATEGICA

RF‐2011‐02347105

Novel Plasmodium falciparum cell‐based assays for new antimalarial drugs



RF‐2011‐02352217

MITOCHONDRIAL CI and CIV DEFICIENCIES: DIFFERENT CLINICAL AND BIOCHEMICAL RENSPONSE TO EPI‐743. AN INTEGRATED APPROACH TO IMPROVE BOTH THE CLINICAL MANAGEMENT AND THE UNDERSTANDING OF THE PATHOGENESIS OF THIS DISORDER




RF‐2011‐02351369

Measuring outcomes to estimate the value of health interventions in breast cancer care


18,5Oncology

RF‐2011‐02349727

How is it possible to define rehabilitation care appropriateness? The impact of an alternative evaluation system on the inappropriateness of health care resources



RF‐2011‐02349456

Pulmonary Rehabilitation in Lung Cancer surgical patients.



18,5Oncology

RF‐2011‐02349065

MULTIMODAL APPROACH TO PERSONALIZED THERAPY IN ANAL CANCER: CREATION OF A BIOMARKER PREDICTIVE PROFILE ADDRESSING TOWARDS NEW THERAPUTIC STRATEGIES


RF‐2011‐02350338

Mechanisms of diabetes resolution after bariatric surgery: role of the gut



Pagina 154 di 231



SCORE.


STRATEGICA

RF‐2011‐02349855

Comparative study on the clinical efficacy and manegement of different feeding strategies in elderly patients with advanced dementia.

Veneto Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02349592

Mechanism(s) underlying differential protection of trastuzumab‐containing therapy depending on site of relapse.


RF‐2011‐02351243

Smoking reduction in a population at high risk of cardiovascular mortality. Randomized control trial of intervention to implement and improve tobacco control strategies in psychiatric settings versus combined pharmacological and psychological intervention

Provincia autonoma Trento Clinical Risk, Prevention and Health Behavior


RF‐2011‐02350440

Fighting drug resistance in non‐small cell lung cancer (NSCLC): a combinatorial approach based on anti‐Kit ligand vaccination

Piemonte Biomedical Oncology 2 ‐ Translational Clinical 18,5Oncology

RF‐2011‐02350942

Risk of human and animal exposure to cyanotoxins through fresh‐ and brackish‐water reared organisms in connected ponds systems

IZS Sardegna Biomedical Veterinary 18,5Food safety and animal welfare

RF‐2011‐02349504

In vivo manipulation of gamma delta Tcell with zoledronate and low dose IL2: improving the efficacy of BRAF inhibitors through a combined targeted/immunotherapy in metastatic melanoma.

Sicilia Clinical Oncology 2 ‐ Translational Clinical 18,5Oncology

Pagina 155 di 231



SCORE.


STRATEGICA

RF‐2011‐02348926

HOMEOSTASIS OF pH AND BICARBONATE CONCENTRATION IN THE AIRWAY SURFACE FLUID AS A TARGET FOR THE TREATMENT OF RESPIRATORY INFECTIONS IN CYSTIC FIBROSIS AND OTHER CHRONIC LUNG DISEASES

GASLINI Biomedical Cell Biology 18,5Infection and immunity

RF‐2011‐02351606

A novel approach for detecting vector‐borne viruses in Sardinia and evaluation of Bluetongue virus evolution.


RF‐2011‐02350946

Evaluation of clinical feasibility and effectiveness of a robotic device for early stage rehabilitation of stroke patients


Biomedical Emerging Technologies and Training in Neurosciences


RF‐2011‐02349457

Congenital cytomegalovirus infection: prognostic factors of virus transmission to the fetus and congenital disease

SAN MATTEO Biomedical Infectious Diseases and Microbiology


RF‐2011‐02349749

NEW ANTIBACTERIAL COATINGS FOR TITANIUM PROSTHESIS TO REDUCE PERIMPLANT INFECTIVE RISK AND

IMPROVE OSSEOINTEGRATION



RF‐2011‐02349452

Generation of human artificial striated muscle

MULTIMEDICA Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02351704

Implementation of a pathology network to improve identification and clinical management of patients with familial hypercholesterolemia

MULTIMEDICA Clinical Healthcare Delivery and Methodologies


Pagina 156 di 231



SCORE.


STRATEGICA

RF‐2011‐02347164

The clinical significance of the association between REM Sleep Behavior Disorder and Parkinson's Disease



RF‐2011‐02349886

BIOLOGICAL AGING AND URBAN POLLUTION



RF‐2011‐02351450

Alteration of steroid hormone pathways and vitamin D in testicular germ cell tumors

PASCALE Biomedical Oncology 2 ‐ Translational Clinical 18,75Oncology

RF‐2011‐02352633

MEDITERRANEAN DIET AND RECURRENCE OF COLORECTAL ADENOMA AND CANCER : A RANDOMIZED CONTROLLED TRIAL

DE BELLIS Biomedical Risk, Prevention and Health Behavior

19Oncology

RF‐2011‐02350684

Impact of the association between elastography and fine‐needle aspirate mutational testing in the prediction of malignancy of thyroid nodules with indeterminate cytology: a prospective analysis.


RF‐2011‐02347689

Role of Type I Interferon in the Cross‐talk between Neutrophils and Dendritic Cells in the induction of adaptive immunity during Mycobacterium tuberculosis and BCG infections.


RF‐2011‐02351908

Development of an artificial larynx for clinical applications

Toscana Biomedical Biobehavioral and Behavioral Processes


Pagina 157 di 231



SCORE.


STRATEGICA

RF‐2011‐02349875

Developmemt of a novel intra‐operative spectroscopic diagnostic technology for diagnosis and better delineation of human brain tumours.

Toscana Biomedical Oncology 2 ‐ Translational Clinical 19Neurological diseases

RF‐2011‐02351560

Integration of Diagnostic tools for fibromyalgia: can tailored therapies be more effective and less expensive?

Piemonte Biomedical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02350218

Predictive value of invasive measurement of left ventricular function during cardiac resynchronization therapy (CRT).

Sicilia Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02352680

Multifunctional Targeted Nanoparticles for minimally Invasive Diagnosis and Therapy of Inflammatory Bowels Diseases and their displasic lesions.

I. O. V. Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02346887

Bowel microbiota and chronic inflammatory bowel diseases: a metabolomic approach



RF‐2011‐02350113

Cognitive rehabilitation after stroke: a randomized controlled trial to compare the effectiveness of different protocols.



RF‐2011‐02350561

The early diagnosis of Alzheimer disease: new tools for the olfactory dysfunction evaluation.



RF‐2011‐02347264

Molecular techniques as epidemiological tools to answer some of the queries about Q fever


Pagina 158 di 231



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STRATEGICA

RF‐2011‐02347881

Development of a novel immunotherapeutic approach to contrast prion‐mediated Abeta oligomer neurotoxicity by intracellular antibody technology




RF‐2011‐02348527

MIND THE GAP: END‐OF‐LIFE IN ADVANCED HEART FAILURE. IMPROVING QUALITY AND CARE OPTIONS.



RF‐2011‐02350943

Finding of common potential new biomarkers for development of diagnostic tools in different neurodegenerative diseases and discovery of new therapeutic agents

IZS Sicilia Biomedical Cell Biology 19Neurological diseases

RF‐2011‐02347871

Identification of novel molecular mechanisms promoting oncogenic RAS signaling


RF‐2011‐02351471

EFFECT OF ATORVASTATIN ON OXIDATIVE STRESS AND INFLAMMATION AND ON OXIDATIVE STRESS‐INDUCED UNFOLDED PROTEIN RESPONSE IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: RELATION WITH ARTERIAL STIFFNESS AND LUNG FUNCTION DECLINE



RF‐2011‐02349480

Lentiviral‐mediated telomere stabilization in hematopoietic stem cell transplantation for graft improvement and GVHD reduction in thalassemia patients

Sardegna Clinical Vascular and Hematology 19The new biotechnologies

Pagina 159 di 231

vincenzo

Sottolineato



SCORE.


STRATEGICA

RF‐2011‐02351943

Report‐AGE Project: clinical and molecular predictors of frailty in aged hospitalized populations with cardiovascular diseases

I.N.R.C.A. Clinical Biology of Development and Aging 19Metabolism disorders and cardiovascular disease

RF‐2011‐02349265

Ultrasound on bioeffects and safety: an integrated approach in evaluating ultrasound‐mediated cell alterations at both cell membrane and genetic level

INAIL Biomedical Cell Biology 19Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02348312

Fractal Lacunarity of Trabecular Bone in Magnetic Resonance Images of Lumbar Vertebras: Clinical Validation of a New Diagnostic Tool for Osteoporosis and Fracture Risk

I.N.R.C.A. Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02349740

Cellular biomarkers of diabetic pathophysiology and complications



RF‐2011‐02351818

Developement and characterization of a new single step treatment for multiple orthopaedic diseases affecting bone or cartilage with the use of bone marrow derived cells and collagenic scaffold

RIZZOLI Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02352814

(SIMBA) Simulation Interface for Miniaturized preterm BAby respiratory system model

Toscana Clinical Bioengineering Sciences and Technologies


RF‐2011‐02351934

Metabolomics of Multiple Myeloma SAN RAFFAELE Milano Biomedical Oncology 1 ‐ Basic Translational 19Oncology

Pagina 160 di 231



SCORE.


STRATEGICA

RF‐2011‐02350730

Optimization, on the basis of Monte Carlo dosimetry, of the therapeutical effectiveness and toxicity of Peptide Receptor Radionuclide Therapy in patients with neuroendocrine tumors

Sicilia Clinical Oncology 2 ‐ Translational Clinical 19Oncology

RF‐2011‐02349002

Nanoparticle‐Enhanced Surface Plasmon Resonance Imaging (NE‐SPRI): PCR‐free ultrasensitive cancer prognosis and therapy prediction

REGINA ELENA Clinical Oncology 2 ‐ Translational Clinical 19The new biotechnologies

RF‐2011‐02350330

Using available stimulation techniques to delay the onset of dementia

S.CAMILLO Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02351655

Identification of molecular targets and markers to manage hormone‐resistant obesity‐associated breast cancer: from in vitro and in vivo models to human tumors


RF‐2011‐02347968

Project title: CEACAM1 is a priviliged cell surface target antigen to design human mAbs in scFv format for multimodal immunotherapeutic intervention of

melanoma and lung carcinoma.



RF‐2011‐02347436

Effects of Neuropeptide Y on the central nervous system neurons of rat models of Alzheimer Disease



RF‐2011‐02351104

Antibiotic strategy and response to microbiologic tests: a study of appropriateness and promptness in case of sepsis.

Piemonte Clinical Infectious Diseases and Microbiology


Pagina 161 di 231



SCORE.


STRATEGICA

RF‐2011‐02352076

Property of donkey's milk : application in human nutrition and its potential usein the preventions and therapy of metabolic infiammatory and cardiovascular diseases associated with obesity.

IZS Mezzogiorno Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02350093

Early detection of cardiotoxicity in cancer patients

ONCOLOGICO DI BARI Clinical Cardiovascular and Respiratory Sciences

19Oncology

RF‐2011‐02351426

ENDOCRINE AND INTRACRINE METABOLISM OF SEX STEROIDS ‐ PROSTATE HEALTH AND CANCER OUTCOMES FROM A 20‐YEAR POPULATION‐BASED STUDY


RF‐2011‐02350453

Fertility preservation in young Oncological female patients

REGINA ELENA Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences

19,25Oncology

RF‐2011‐02350026

Proximal versus Distal approach in the upper limb rehabilitation in stroke patients using robotic platforms: effects on the motor performance and functional recovery.




RF‐2011‐02348106

Alternative strategies for cognitive rehabilitation after stroke: which role for not invasive brain stimulation? Effects of transcranial magnetic stimulation in recovery of hemispatial attention and language in subacute and chronic patients.



Pagina 162 di 231



SCORE.


STRATEGICA

RF‐2011‐02352295

NEUROPSYCHOLOGICAL AND fMRI STUDIES TO EVALUATE THE EFFECTS OF COGNITIVE REHABILITATION IN PARKINSON¿S DISEASE

Provincia autonoma Trento Clinical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02347760

Urine proteome analysis: A possible method that may allow noninvasive differential diagnosis of diabetic

nephropathy andgive new insight into monogenic type 2 diabetes


Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02350975

Immunological and virological predictors of clinical outcome in chronic HBV patients discontinuing anti‐viral treatment

SPALLANZANI Biomedical Immunology 19,5Infection and immunity

RF‐2011‐02349348

Role of plasma dysregulated microRNAs in the diagnosis and screening of Human Malignant Pleural Mesothelioma (MPM)

Emilia‐Romagna Biomedical Oncology 2 ‐ Translational Clinical 19,5Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02350564

Effects of a late add‐on therapy of pegylated interferon (peg‐IFN¿) to ongoing nucleos(t)ide analogs (NUCs) in patients with chronic hepatitis B (CHB): dissecting systemic and hepatic immune restoration



RF‐2011‐02351852

zEC‐ zero Errors in Chemotherapy: process modelling for more effective ICT solutions in antiblastic treatment management

I.E.O. Clinical Healthcare Delivery and Methodologies

19,5Oncology

RF‐2011‐02350811

The impact of HBV and HCV expression and replication on cellular differentiation, metabolism and oncogenesis in extra‐ or intra‐hepatic stem cells induced to differentiate along the hepatocytic lineage



Pagina 163 di 231



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STRATEGICA

RF‐2011‐02350816

Rapid eye movement sleep behavior disorder (RBD): Prevalence study in Italian general population aged > 50 years



RF‐2011‐02352794

Development and monitoring of a Parkinson's disease network in Tuscany



RF‐2011‐02349864

Discovery and translational research of aggressive B‐cell lymphomas of still unknown pathobiology


RF‐2011‐02350858

Predictive and prognostic value of molecular markers for glioma in clinical decision making

CARLO BESTA Clinical Oncology 2 ‐ Translational Clinical 19,5Oncology

RF‐2011‐02351329

Identification of biomarkers associated with clinical response and/or toxicity to treatment with the JAK2 inhibitor ruxolitinib in patients with myelofibrosis


RF‐2011‐02348548

High‐coverage next generation sequencing to detect the presence and intra‐tumor frequency of mutations in the EGFR pathway activating genes: predictive value on the response to anti‐EGFR therapy in metastatic colorectal cancer.



RF‐2011‐02347285

SISTEMATIC APPLICATION OF A STANDARDIZED COMPREHENSIVE GERIATRIC ASSESSMENT TO PREDICT OUTCOME AND POSSIBILITY OF TREATMENT ON ELDERLY CANCER PATIENTS


Pagina 164 di 231



SCORE.


STRATEGICA

RF‐2011‐02349828

Exposure and health effects of Ultrafine Particles at urban hotspots

INAIL Biomedical Population Sciences and Epidemiology


RF‐2011‐02352021

Application of novel biotechnologies for assessment of the vector competence of wild populations of Culicoides obsoletus for the Bluetongue virus


RF‐2011‐02349178

A Prospective Cohort Study to Evaluate the Prognostic Value of Mobile Genetic Element Insertions in Non‐Small Cell Lung Cancer (NSCLC).

I.N.R.C.A. Clinical Oncology 2 ‐ Translational Clinical 19,5Oncology

RF‐2011‐02350863

Characterization of molecular markers that are associated with DNA‐damage repair pathways to identify rectal cancer patients who are responsive to chemioradiotherapy


RF‐2011‐02349796

Definition of a new predictive model to assess the complexity of patients hospitalized in Internal Medicine, with particular reference to cardiovascular

outcomes

Lombardia Clinical Healthcare Delivery and Methodologies


RF‐2011‐02351539

Validation of a Prognostic Gene Signature in Urine Samples from Prostate Cancer Patients


RF‐2011‐02350423

New molecurar markers to characterize benign and malignant thyroid cells.


Pagina 165 di 231



SCORE.


STRATEGICA

RF‐2011‐02347457

Post‐transplant hematopoiesis: a model to understand self‐renewal mechanisms of hematopoietic stem cells

GASLINI Biomedical Vascular and Hematology 19,5Oncology

RF‐2011‐02352502

The gC1q domain of EMILIN1 as an ideal backbone to develop a versatile drug carrier

C.R.O. AVIANO Biomedical Oncology 2 ‐ Translational Clinical 19,5Oncology

RF‐2011‐02350227

Genetic basis of taste perception, life style, health status and colorectal cancer risk.

Piemonte Biomedical Genes, Genomes and Genetics 19,5Oncology

RF‐2011‐02348610

Personalized multidisciplinary therapy in head and neck cancer based on clinical and molecular markers

C.R.O. AVIANO Clinical Oncology 2 ‐ Translational Clinical 19,5Oncology

RF‐2011‐02348921

Expression of PARP1 and LDOC1 genes in subjects with Down syndrome and identification of new markers of neurodegenerative disorders in these subjects.

OASI MARIA S.S. Biomedical Genes, Genomes and Genetics 19,5Neurological diseases

RF‐2011‐02347702

The effects of intensive arm training on upper extremity motor recovery in chronic stroke survivors. Identification of biomarkers related to clinical outcome.



RF‐2011‐02349122

Evaluation of denosumab effects on RANKL/RANK signalling in human osteosarcoma cells.

Abruzzo Biomedical Oncology 1 ‐ Basic Translational 19,5Oncology

RF‐2011‐02352782

Oxidative stress and vitamin D as potential contributors for cardiometabolic complications in subclinical and overt hypothyroidism.



Pagina 166 di 231



SCORE.


STRATEGICA

RF‐2011‐02350092

Phase contrast mammography with synchrotron radiation in the follow‐up of patients treated with conservative surgery for breast carcinoma

Friuli‐Venezia Giulia Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering

19,75Oncology

RF‐2011‐02349448

Genetic risk prediction of atrial fibrillation recurrences: new insight from next generation sequencing

Emilia‐Romagna Clinical Genes, Genomes and Genetics 19,75Metabolism disorders and cardiovascular disease

RF‐2011‐02349399

Antenatal human heart development Lombardia Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02352025

Host‐pathogen interactions: Chlamydiae cronic infections; a primary role in human diseases. Biomarkers and diagnostic tools for clinical evaluation.



RF‐2011‐02351323

Longitudinal comparative study to assess progression and predictive factors of ognitive decline in patients with advanced Parkinson's disease treated with deep brain stimulation of the subthalamic nucleus stimulation and pharmacological therapy

S.CAMILLO Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02347194

INNOVATIVE TRANSLATIONAL APPROACHES TO IDENTIFY IMMUNE CORRELATES OF PROTECTION IN AIDS VACCINE TRIALS


RF‐2011‐02348406

Decision making and learning impairments associated with focal cerebral lesions

Lazio Clinical Integrative, Functional, and Cognitive Neuroscience


Pagina 167 di 231



SCORE.


STRATEGICA

RF‐2011‐02347582

Understanding high‐risk HPV‐induced derangements in cervical cancer to address patients' prognosis and therapy and to defeat the viral oncogenic machinery

REGINA ELENA Biomedical Oncology 1 ‐ Basic Translational 20Oncology

RF‐2011‐02352169

Investigations of the molecular mechanisms linking poly(ADP‐ribosyl)ation to relapses and progression of multiple sclerosis



RF‐2011‐02349782

In vitro and in vivo effects of post‐transplant cyclophosphamide (PT‐CY) in patients receiving hematopoietic stem cell transplantation from HLA haploidentical

family donors.



RF‐2011‐02347552

Familial Hyperaldosteronism: Studies in Humans and in Animal Models

Piemonte Biomedical Genes, Genomes and Genetics 20Metabolism disorders and cardiovascular disease

RF‐2011‐02347506

GENE‐ENVIRONMENT INTERACTIONS, VITAMIN D STATUS AND SUSCEPTIBILITY: IMMUNE RESPONSE AND PULMONARY TUBERCULOSIS RISK IN SICILY

Sicilia Biomedical Population Sciences and Epidemiology


RF‐2011‐02347487

ROLE OF GROUP I METABOTROPIC GLUTAMATE RECEPTORS IN THE PATHOGENESIS OF AMYOTROPHIC LATERAL SCLEROSIS AND IN ITS PHARMACOLOGICAL CONTROL

I.N.R.C.A. Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02348156

Radiation effects of low and/or protracted doses: from the mechanisms underlying the biological effects to the impact on public health


Pagina 168 di 231



SCORE.


STRATEGICA

RF‐2011‐02349586

ROLE AND IMPACT OF DNA VIRUSES IN AUTOIMMUNE DISEASES

Emilia‐Romagna Biomedical Immunology 20Infection and immunity

RF‐2011‐02351075

Orthopoxvirus infection in Italy: diffusion and evaluation of innovative vaccine candidates



RF‐2011‐02351272

An integrated genomic and immunological approach to novel monitoring and therapeutic strategies for HBV and HCV infections



RF‐2011‐02352210

Achieving mucosal and systemic immunity by exploiting vitamin A metabolites as co‐adjuvants in Tuberculosis vaccination


RF‐2011‐02349584

Role of microRNAs in successful aging Abruzzo Biomedical Biology of Development and Aging 20Metabolism disorders and cardiovascular disease

RF‐2011‐02348269

Use of phages as decontamination agents in the production of traditional Italian food: evaluation of effectiveness and possible risk for the consumer

IZS Lombardia e dell'Emilia Biomedical Veterinary 20Food safety and animal welfare

RF‐2011‐02349516

Guidelines for Health Impact Assessment Emilia‐Romagna Clinical Population Sciences and Epidemiology


RF‐2011‐02349503

Searching for a common pathogenetic pathway causing muscle misfunctioning in different laminopathies

RIZZOLI Biomedical Cell Biology 20The new biotechnologies

Pagina 169 di 231



SCORE.


STRATEGICA

RF‐2011‐02352536

Gastrointestinal Tract Permeability and Inflammation in HIV‐Infected patients with mild to moderate Chronic Kidney Disease: a cross‐over, double blind, randomized clinical trial


RF‐2011‐02350536

Improvement of diagnosis and immunotherapy appropriateness in mould allergic patients by characterization and standardization of mould allergenic extract.

ISS Biomedical Immunology 20Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02349704

Mechanism of inhibition and reversion of omega‐3‐Polyunsaturated Fatty Acids on the growth of intestinal polyps in APC Min/+ mice

DE BELLIS Biomedical Oncology 1 ‐ Basic Translational 20Oncology

RF‐2011‐02347860

IMMUNOCARRIER DEVELOPMENT AND VALIDATION STUDY FOR TARGETED

IMAGING/DRUGDELIVERY IN CANCER THERAPY

SAN RAFFAELE Milano Biomedical Oncology 2 ‐ Translational Clinical 20Oncology

RF‐2011‐02347811

Abnormalities in T lymphocyte subsets and phagocytes in Cutaneous T‐cell Lymphomas (CTCL): potential mechanisms driving immunodeficiency and increased susceptibility to infections.

Piemonte Biomedical Immunology 20Infection and immunity

RF‐2011‐02352720

Improving clinical pathways of patients candidated to cardiac surgery by process modeling

MONZINO Clinical Healthcare Delivery and Methodologies


Pagina 170 di 231



SCORE.


STRATEGICA

RF‐2011‐02352725

Identification of novel markers of disease through the analysis of the role and impact of mesenchymal stem cells and of miRNA/mRNA network on the progression of bicuspid aortic valve‐related aortopathy



RF‐2011‐02352672

Changing professional behaviors and measuring the quality of acute stroke care


Biomedical Healthcare Delivery and Methodologies


RF‐2011‐02350634

Papillary Thyroid Cancer gender disparity: is the estrogen cancerogenesis related to stemness factors?

Veneto Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences

20Oncology

RF‐2011‐02351485

Clinical relevance of biomarkers involved in EGFR signalling pathway in the outcome of KRAS wild‐type colorectal cancer patients treated with cetuximab‐based therapy

Campania Clinical Oncology 2 ‐ Translational Clinical 20Oncology

RF‐2011‐02350718

SARCOGLYCANS: SIGNALLING FUNCTION IN DIFFERENT CELLULAR COMPARTMENTS AND POSSIBLE ROLE

INGENETIC THERAPIES.

NEUROLESI Biomedical Genes, Genomes and Genetics 20The new biotechnologies

RF‐2011‐02352279

The role of the airways microbiome in the development of chronic lung infections in CF patients and implications for personalized antibiotic interventions

Provincia autonoma Trento Biomedical Infectious Diseases and Microbiology


RF‐2011‐02350923

Producing iPS cells: a biobank service for translational genetic research

Liguria Biomedical Genes, Genomes and Genetics 20The new biotechnologies

Pagina 171 di 231



SCORE.


STRATEGICA

RF‐2011‐02352287

Gender and age‐related differences in motility and permeability responses in human colon: role of muscarinic receptors

DE BELLIS Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02350719

ROLE OF WT1 AND ITS ISOFORMS IN HEMATOPOIETIC MALIGNANCIES

Campania Clinical Genes, Genomes and Genetics 20Oncology

RF‐2011‐02349104

Impact of early extracorporeal photopheresis (ECP) on the management of acute Graft versus host disease (aGVHD): clinical, biological and economical implications

Friuli‐Venezia Giulia Clinical Immunology 20The new biotechnologies

RF‐2011‐02347864

Molecular diagnosis of thyroid nodules: evaluation of candidate microRNA in fine‐needle aspiration biopsy samples and use of circulating microRNA as potential biomarkers to differentiate malignant from benign undetermined nodules.


RF‐2011‐02351864

Safety and nutritional adequacy of donkey's milk in treating cow's milk allergic children

Piemonte Clinical Immunology 20Food safety and animal welfare

RF‐2011‐02347154

Potential health and environmental risks associated to air pollutants in the petrochemical site of Basilicata

Basilicata Biomedical Population Sciences and Epidemiology


RF‐2011‐02351778

Novel molecular mechanisms in pathogenesis of Male Breast Cancer (MBC)

Sicilia Biomedical Genes, Genomes and Genetics 20Oncology

Pagina 172 di 231



SCORE.


STRATEGICA

RF‐2011‐02347785

Detection of thyroid cancer biomarkers by SEREX: development of a new diagnostic assay and identification of targets for immunotherapy.

Campania Biomedical Oncology 2 ‐ Translational Clinical 20Oncology

RF‐2011‐02347171

Assessment of cancer risk behaviours of immigrant population in Italy and the impact in the socio‐sanitary context. Strategies for a conscious prevention.

PASCALE Clinical Risk, Prevention and Health Behavior

20Oncology

RF‐2011‐02352624

Endocrine‐metabolic pattern and Mediterranean Diet biomarkers in the occurrence of breast cancer relapses


RF‐2011‐02351230

In vitro and in vivo antimicrobial activities of innovative and unconventional drug combinations to treat infections caused by multi‐drug‐resistant (MDR), extensively‐drug‐resistant (XDR) or pandrug‐resistant (PDR) Acinetobacter baumannii and Pseudomonas



RF‐2011‐02347944

From microGIST to overt GIST: dissection of the molecular alterations underlying GIST malignant evolution


RF‐2011‐02348225

Role of HIV‐1 infection on colorectal carcinoma onset and progression: development of novel therapeutic strategies

ISS Biomedical AIDS and Related Research 20,25Oncology

Pagina 173 di 231



SCORE.


STRATEGICA

RF‐2011‐02350319

Effect of cognitive stimulation with computerized‐training (Rehacom) on cerebral metabolism evaluated by 18F‐FDG‐PET in patients with mild cognitive impairment (MCI)

Liguria Clinical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02352457

A a case‐control record‐linkage study on occupational aspects of neurological diseases



RF‐2011‐02350385

Estrogen, inflammation and cholesterol homeostasis: a "Bermuda Triangle" for CVD risk?



RF‐2011‐02350891

Discovery and validation of clinical biomarkers for lung neuroendocrine neoplasms from formalin‐fixed paraffin‐embedded tissues

Sardegna Biomedical Oncology 2 ‐ Translational Clinical 20,5Oncology

RF‐2011‐02347775

Mediterranean diet and gut microbiota: an operational agorithm to unveil food effects on healthy growth and disease control



20,5Food safety and animal welfare

RF‐2011‐02347309

Ranking patient‐oriented outcome measures with evidence‐based criteria in

brain tumor patients

Veneto Clinical Oncology 2 ‐ Translational Clinical 20,5Oncology

RF‐2011‐02347821

Arterial and Venous thrombotic risk in women approaching ART procedures: evaluation of thrombophilia screening. ‐ A prospective cohort study.


Biomedical Healthcare Delivery and Methodologies


Pagina 174 di 231



SCORE.


STRATEGICA

RF‐2011‐02349774

Treatment of extremely high lipoprotein(a) levels with LDL‐apheresis in young patients with documented cardiovascular disease: a proof of concept trial



RF‐2011‐02349807

Occupational health risk in dynamic olfactometry. Risk assessment for workers in the olfactometric laboratory and establishment of safety procedures for the implementation of the European Standard method for determination of odour concentration.

MAUGERI Biomedical Risk, Prevention and Health Behavior


RF‐2011‐02351568

MicroRNA detections in Exhaled Breath Condensate and blood of Malignant Mesothelioma Patients and Healthy Subjects exposed to Asbestos.

MAGGIORE Biomedical Oncology 1 ‐ Basic Translational 20,5Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02351390

Role of angiotensin‐converting enzyme inhibitors on cardioprotection against anticancer therapy‐induced cardiotoxicity: in vivo clinical evidences along with in vitro studies.


RF‐2011‐02352828

Cost‐effectiveness of Transcatheter Aortic Vale Implantation in high‐risk patients with severe aortic valve stenosis: a real world study in the Italian public health care system



RF‐2011‐02349061

Growth factors and lipid mediators signalling: shared intracellular pathways regulating the complex and dynamic process of wound healing

SAN GALLICANO Biomedical Cell Biology 20,5Metabolism disorders and cardiovascular disease

Pagina 175 di 231



SCORE.


STRATEGICA

RF‐2011‐02352399

Prediction of childhood visceral adiposity and hypertension by body composition measurement in early life in premature and small for gestational age infants.

BURLO GAROFALO Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351653

STRATEGIES FOR THE CONTROL OF SKIN INFECTIONS BY DRUG RESISTANT BACTERIA WITH NATURAL PRODUCTS.



RF‐2011‐02351827

Human oncogenic risk from consumption of beef red meat

CROB Biomedical Oncology 1 ‐ Basic Translational 20,5Food safety and animal welfare

RF‐2011‐02347444

Mechanisms underlying cognitive dysfunction and decline in Parkinson's disease and related disorders: brain damage, functional reorganization, and effects of BDNF polymorphisms.



RF‐2011‐02350288

STRATEGIES TO DECREASE THE INCIDENCE OF INFECTIONS/COLONIZATIONS BY GRAM NEGATIVE MULTIDRUG‐RESISTANT BACTERIA IN INTENSIVE CARE UNITS. A PROSPECTIVE, MULTICENTER TRANDOMIZED STUDY.



RF‐2011‐02348536

Role of Prostanoid Metabolism in Aortic Valve Calcification

Veneto Biomedical Vascular and Hematology 20,5Metabolism disorders and cardiovascular disease

RF‐2011‐02348469

Phenotyping Cheyne‐Stokes respiration in heart‐failure patients: a first step towards

effective individualized treatment

MAUGERI Biomedical Cardiovascular and Respiratory Sciences


Pagina 176 di 231



SCORE.


STRATEGICA

RF‐2011‐02347153

Nitrosation of drugs of abuse in human saliva at the acidic pH of the stomach: mechanism of transformation and evaluation of the associated carcinogenic risk.


RF‐2011‐02350951

Antibody deficiency disorders as risk factors for gastric cancer

Emilia‐Romagna Clinical Immunology 20,5Oncology

RF‐2011‐02352644

Development and validation of a predictive model of mortality and hospitalization in patients with diabetes using administrative databases.

Puglia Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02350660

Influence of adipose derived mesenchymal stem cells and adipocytes on residual cancer cells growth in tumor bed.



RF‐2011‐02347074

Role of Toll‐like receptors in chemoresistance of chronic lymphocytic leukemia


RF‐2011‐02350035

Dissecting SOX2 role in breast cancer progression: from the epithelial‐to‐mesenchymal transition to metastasis onset


RF‐2011‐02347926

Proposal of a methodological procedure for animal biomonitoring in contaminated areas

IZS Lazio e della Toscana Biomedical Veterinary 20,5Food safety and animal welfare

Pagina 177 di 231



SCORE.


STRATEGICA

RF‐2011‐02348632

Environmental, food related (mycotoxins) and genetic basis of Neural Tube Defects susceptibility n Italian and Sudanese populations.

MEDEA Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02349171

Relationship between 3D BCR structure, microenvironment and response to BCR inhibitors/4HPR, to design novel Chronic Lymphocytic Leukemia combination therapies.



RF‐2011‐02352813

Human Cardiac Stem Cell Therapy in Patients with Severe Heart Failure Undergoing LVAD Implantation.



RF‐2011‐02352114

miRNAs role in Longevity and their relation to cancer survival

Sardegna Biomedical Biology of Development and Aging 21Oncology

RF‐2011‐02347830

AN EXTENSIVE STUDY ON EVOLUTION AND PROGNOSIS IN MONOCLONAL GAMMOPATHIES: THE ROLE OF IMMUNOPHENOTYPE, CYTOGENETICS AND HLC RATIO IN PC AND Pre‐PC SUBCLONAL COMPARTMENTS


RF‐2011‐02352303

GENOMIC AND PROTEOMIC STUDIES ON EARLY STAGE PULMONARY ADENOCARCINOMA: identification of pathogenesis markers relevant for cancer screening and personalized therapy.

Abruzzo Biomedical Healthcare Delivery and Methodologies

21Oncology

Pagina 178 di 231



SCORE.


STRATEGICA

RF‐2011‐02350247

Human infection from exposure to norovirus (NoV): improving and harmonization of diagnostic techniques, correlation between clinical cases and contaminated food and assessment of dose‐response

IZS Venezie Biomedical Infectious Diseases and Microbiology


RF‐2011‐02350547

Neuroendocrine storm and postoperative depression in cardiac surgery



RF‐2011‐02351768

A new scenario for ALS/FTD: genetic contribution in outlier phenotypes


Biomedical Genes, Genomes and Genetics 21Neurological diseases

RF‐2011‐02351735

Project Title: Respiratory viral infections: evaluation of the clinical value of virological diagnosis and study of the role of innate immune response in determining increased severity



RF‐2011‐02349931

New strategies for the eradication of HIV reservoirs


RF‐2011‐02350339

Effects of repetitive transcranial magnetic stimulation after early stroke: a study in children and developing rats



RF‐2011‐02350327

Implementation of a next generation multigene test for prognostic stratification and tailored therapy in glioblastoma patients

Emilia‐Romagna Biomedical Oncology 2 ‐ Translational Clinical 21Oncology

Pagina 179 di 231



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STRATEGICA

RF‐2011‐02346790

MOLECULAR EVENTS RESPONSIBLE FOR MIGRATORY PLASTICITY AND INVADOPODIA FORMATION IN BONE METASTASIS FROM BREAST CARCINOMA

GALEAZZI Biomedical Oncology 1 ‐ Basic Translational 21Oncology

RF‐2011‐02351455

Identification and validation of new molecular targets in the treatment of EGFR‐resistant NSCLC


RF‐2011‐02349396

New pathobiologic prognostic factors in colorectal cancers: the role of circulating tumor cells, mismatch repair system's competence, and tumor deposits in non metastatic rectal cancer.

IST.TUMORI MILANO Clinical Digestive, Kidney and Urological Systems

21Oncology

RF‐2011‐02351342

CHEMOPREVENTIVE EFFICACY OF GREEN TEA EXTRACTS IN PROSTATE CANCER PROGRESSION. CLINICAL AND MOLECULAR STUDY ON MECHANISM OF ACTION

SAN RAFFAELE Milano Clinical Oncology 2 ‐ Translational Clinical 21Oncology

RF‐2011‐02351897

Study of motor cortex electrical activity and neuroinflammatory hypothesis in ALS.



RF‐2011‐02351732

Omic and biosensor new approaches to detect hormonal growth promoters in food‐producing animals

IZS Mezzogiorno Biomedical Genes, Genomes and Genetics 21Food safety and animal welfare

RF‐2011‐02349454

The role of Integrin alpha5/beta1 as a potential therapeutic target in breast cancer bone metastasis

Lazio Biomedical Oncology 2 ‐ Translational Clinical 21Oncology

Pagina 180 di 231



SCORE.


STRATEGICA

RF‐2011‐02351324

INTERACTION OF ACUTE MYELOID LEUKEMIA CELLS WITH NATURAL KILLER CELLS: BIOLOGICAL ASPECTS AND CLINICAL IMPLICATIONS


RF‐2011‐02351223

Study of genetic variability oF HCV genotype 4 strains circulating in Lazio and analysis of their resistance pattern correlated to new DDA drug



RF‐2011‐02349741

Development of novel 'tailored' therapy in acute myeloid leukemia (AML) with NPM1 gene mutations

Umbria Biomedical Oncology 2 ‐ Translational Clinical 21Oncology

RF‐2011‐02351581

Discovery and validation of circulating biomarkers for the early diagnosis, assessment of prognosis and response to treatments in primary liver tumors on cirrhosis


RF‐2011‐02350567

Focus on incidence and diversity of intestinal methanogens and host‐gut microbiota metabolic interactions in healthy and diseased human groups.

Piemonte Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351428

Surveillance on the use of oral anticoagulant drugs in patients with atrial fibrillation

MAGGIORE Clinical Vascular and Hematology 21Metabolism disorders and cardiovascular disease

Pagina 181 di 231



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STRATEGICA

RF‐2011‐02349834

Pilot study of a combination of an mTOR inhibitor (everolimus) and capecitabine administered with a metronomic

schedulein patients undergoing liver transplantation for hepatocellular carcinoma at high risk of recurrence.


RF‐2011‐02349514

Transcranial Direct Current Stimulation combined with Speech Therapy in Acute and Chronic Post‐stroke Aphasic Patients: a double blind, sham‐controlled, randomized study



RF‐2011‐02347363

Potential relevance of non classical human leukocyte antigens (HLA)‐G and ‐E and gelatinases as markers of tumor invasion and progression and their association with Computed Tomography and Magnetic Resonance Imaging perfusion findings in patients with hig



RF‐2011‐02349510

GENOMIC CHARACTERISTICS OF REGULATORY T‐CELLS IN CHRONIC LYMPHOCYTIC LEUKEMIA: RELATIONSHIP TO CLINICAL OUTCOME AND POTENTIAL IMPLICATION FOR TREATMENT

CROB Clinical Oncology 2 ‐ Translational Clinical 21Oncology

RF‐2011‐02347400

A role for the modulation of Rho GTPase signalling in the therapy of Fragile X syndrome



RF‐2011‐02347576

Striatal cholinergic transmission as a target for therapeutic intervention in Tourette Syndrome



Pagina 182 di 231



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STRATEGICA

RF‐2011‐02350358

Inflammatory and oxidative stress biomarkers associated with carotid atherosclerotic disease progression: a multi‐marker strategy to identify patients at risk of clinical events

ISS Biomedical Vascular and Hematology 21Metabolism disorders and cardiovascular disease

RF‐2011‐02350869

Decisions of health care management and cost accounting in Neuroscience and Severe Acquired Brain Damage (SABD)

NEUROLESI Clinical Healthcare Delivery and Methodologies


RF‐2011‐02352239

Genome wide association study and heritability of recently proposed cardiovascular risk factors such as arterial stiffness, endothelial dysfunction, blood pressure variability and pulse pressure amplification in an isolated population living in Ogliastra



RF‐2011‐02347051

Tregs/Th17 Imbalance, Intrahepatic Cytokine Milieu and Immune Dysregulation in Autoimmune Hepatitis


RF‐2011‐02348735

Dysglicemia in hypertensive and normotensive adult and old subjects: role of glucocorticoids and Metallothioneins. From pathophysiology to cardiovascular risk prevention. Acronym: DYGAM‐AGE



RF‐2011‐02350914

Analytical and clinical validation of assays for PARP1/PAR related biomarkers.


RF‐2011‐02351949

Continuity of care and health expenditure for children with complex needs or chronic health conditions


21Oncology

Pagina 183 di 231



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STRATEGICA

RF‐2011‐02349219

Proposal of an animal platform for assessing the tumoral cell response to anti‐angiogenic or cytotoxix antineoplastic agents based on multimodality molecular imaging: multiparametric assessment by optical imaging, microMagnetic Resonance Imaging, and micr

Friuli‐Venezia Giulia Biomedical Oncology 2 ‐ Translational Clinical 21Oncology

RF‐2011‐02349657

Keratoconus and autoimmune thyroid disorders

HUMANITAS Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349902

Identification and comparison of stool and plasma microRNA signatures as colorectal cancer markers


RF‐2011‐02351178

Modulation of treatment of elderly patients with Diffuse Large B‐cell Lymphoma guided by Comprehensive Geriatric Assessment combined with metabolomic investigations to identify specific patients frailty profiles predictive of treatment toxicity


RF‐2011‐02347636

Development and standardization of biosensor‐based assays for the fast and sensitive detection of food‐borne bacteria in food

IZS Mezzogiorno Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02350001

Effects of robotic‐aided rehabilitation on the wrist joint in hemiparetic patients: an fMRI study

ISS Clinical Musculoskeletal, Oral and Skin Sciences


Pagina 184 di 231



SCORE.


STRATEGICA

RF‐2011‐02349863

Effectiveness and costs‐effectiveness analysis of a caring model for hospitalized cancer patients with severe acute clinical problems


21,5Oncology

RF‐2011‐02352243

Non‐invasive treatment of facet joint osteoarthritis low back pain by Magnetic Resonance guided Focused Ultrasound Surgery (MRgFUS): techniques and protocols optimization, clinical study and immune response assessment

Sicilia Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02349986

ICT for Quality Assurance and Advanced Information Management in Immunology and Oncology Biobanking: a Bridge Between Care and Research

HUMANITAS Clinical Healthcare Delivery and Methodologies


RF‐2011‐02349214

Activation‐Induced Cytidine Deaminase as Oncogenic Mutator in HCV‐related B‐cell Non‐Hodgkin¿s Lymphoma and Hepatocellular Carcinoma: A Single Cell‐level Study.

Puglia Biomedical Oncology 1 ‐ Basic Translational 21,5Oncology

RF‐2011‐02348314

Study on the interaction of polyomavirus JC (JCPyV) with stem cells‐derived lineages



RF‐2011‐02347229

Functional Immune Reconstitution Evaluation of Immune Senescence Process in HIV Mono‐infected and Co‐infected Patients Undergoing cART (FIRE Study)


RF‐2011‐02349447

Coronary Arteriogenesis with combined Heparin and EXercise therapy in Chronic refractory Angina (CARHEXA study)



Pagina 185 di 231



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STRATEGICA

RF‐2011‐02348311

IMPACT OF COMPUTERIZED PRESCRIPTION ON COMPLIANCE WITH GUIDELINES‐RECOMMENDED PROCESS IN PNEUMONIA. A STUDY TO ANALYZE A BETTER CONTROL OF ANTIBIOTIC THERAPY.



RF‐2011‐02348452

Study of the role played by the Na+‐Ca2+ exchanger 1 (NCX1) for the development of the cardiac damage to bacterial infections causing hypertrophic heart response

Marche Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02350600

Validation of Reticulocalbin 1 (RCN‐1) as a new marker for renal cell carcinoma (RCC) in a large retrospective study by IHC and regulation analysis of protein expression.


RF‐2011‐02350457

Multiplatform approach to dissect Wilms tumor heterogeneity


RF‐2011‐02350917

CANCER IN IMMUNOCOMPROMISED POPULATIONS, HIV‐INFECTED (HIV) PATIENTS, ORGAN TRASPLANT RECIPIENTS (OTRs) and HIV‐OTRs: NEW PREVENTIVE and TREATMENT STRATEGIES FOR SOLID TUMOURS


RF‐2011‐02350550

Role of hypothermia in organ dysfunction after cardiac arrest

Sicilia Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02350661

Risk assessment of patients and medical operators in diagnostic and therapeutic cancer procedures: clinical, chemical, physical and humanization aspects


21,5Oncology

Pagina 186 di 231



SCORE.


STRATEGICA

RF‐2011‐02351846

Use of amiodarone and derivatives for treatment/prophylaxis of viral hemorragic fevers.

Veneto Biomedical Infectious Diseases and Microbiology


RF‐2011‐02346888

Analysis of cardiomyopathies and arrhythmogenic syndromes associated with high risk of sudden death: an integrated approach of functional genomics and clinical‐instrumental parameters.

Puglia Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02350788

Prognostic and predictive potential of miRNA signatures linking cancer to inflammatory and fibrotic diseases

SAN MATTEO Biomedical Oncology 1 ‐ Basic Translational 21,5Oncology

RF‐2011‐02352866

Early detection of neurodegenerative diseases. The case of Alzheimer's disease

Liguria Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02350851

Development of innovative methods for radiobiological optimization of molecular radiotherapy treatments

I.E.O. Clinical Bioengineering Sciences and Technologies


RF‐2011‐02352895

INNOVATIVE THERAPY FOR OSTEOARTHRITIS: FROM CLASSICAL VISCOINDUCTION TO INTRA‐ARTICULAR INFILTRATION OF MULTILAYERED HYALURONIC ACID AND CHITOSAN MICROCAPSULES FOR PRECISE POINT OF CARE DELIVERY AND CONTROLLED RELEASE PROFILE

Lazio Clinical Bioengineering Sciences and Technologies


RF‐2011‐02350632

Comprehensive evaluation of the potential of engineered nanoparticles to induce bronchial hyperreactivity in exposed workers.



Pagina 187 di 231



SCORE.


STRATEGICA

RF‐2011‐02352493

MULTICENTER, RANDOMIZED, CLINICAL TRIAL ON THE COMPARISON BETWEEN EARLY SURGERY AND CONVENTIONAL THERAPY IN INFECTIVE ENDOCARDITIS. THE EARLY STUDY.

Piemonte Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02352002

Enabling assessment of attention and motivation during post‐stroke robot‐assisted rehabilitation to improve patient adherence to treatment and outcome.

MAUGERI Clinical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02350383

Development of a cheap point‐of‐care assay for molecular diagnosis of legionellosis



RF‐2011‐02347473

Nanotechnology for the delivery of Zoledronic Acid: a new opportunity against cancer


RF‐2011‐02351383

Safety of general anaesthesia (GA) in neonatal and pediatric age: neurotoxicity of drugs as revealed by neuropsychological indexes and biomarkers



RF‐2011‐02352437

QOLIBRI ‐ Quality of Life after Brain Injury: the new challenge for tomorrow

SANTA LUCIA Biomedical Risk, Prevention and Health Behavior


RF‐2011‐02352329

Role of bilateral STN DBS on impulse control disorders and related behaviors in Parkinson's disease: a quasi‐experimental clinical trial



Pagina 188 di 231



SCORE.


STRATEGICA

RF‐2011‐02351635

Antibiotic resistant bacteria and ready to eat salads: are they really ready to be

consumed?


RF‐2011‐02349728

Measured physiological and psycological outcomes with hypnotic behavioral adjuncts as an experimental tool in laboratories of interventional cardiac procedures

Piemonte Clinical Biobehavioral and Behavioral Processes


RF‐2011‐02351295

biomarkers characterization in the glatiramer acetate therapy of relapsing multiple sclerosis

Puglia Biomedical Emerging Technologies and Training in Neurosciences


RF‐2011‐02346830

Cyclodextrin cross‐linking ‐ nanosponges (CD‐NS) for melanoma‐targeted drug delivery

Piemonte Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02350257

Antimicrobial peptide‐based nanotherapeutics to prevent biofilm formation or to eradicate pre‐formed biofilms associated with catheter‐related, antibiotic resistant nosocomial infections



RF‐2011‐02352171

Genetic, molecular and bioinformatics approaches for early detection of HIV‐associated neurocognitive disorders (BioHAND Study)

Puglia Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02346751

The subcutaneous immunoglobulins as first‐line therapy of chronic inflammatory neuropathies. A pilot study.

Piemonte Clinical Brain Disorders and Clinical Neuroscience


Pagina 189 di 231



SCORE.


STRATEGICA

RF‐2011‐02352374

Innovative Nanomedicines for the Efficacious Treatment of Dogs affected by Leishmaniasis

IZS Sicilia Biomedical Veterinary 22Food safety and animal welfare

RF‐2011‐02349199

CANCER RISK EVALUATION IN A COHORT OF FARMERS EXPOSED TO ZOONOTIC AGENTS

IZS Sicilia Biomedical Population Sciences and Epidemiology


RF‐2011‐02352712

Clinical and Economical Impact of a Multiplex PCR‐Based Assay for a rapid Detection of Pathogens Causing Sepsis in non‐hospitalized onco‐hematological Patients with neutropenic fever



RF‐2011‐02349692

Point‐of‐care lung ultrasonography in the bedside evaluation of patients in the critical care and emergency settings

Piemonte Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02347193

Characterization of human amniotic mesenchymal stem cells (hA‐MSCs)

isolated from obese women at deliveryto identify gene or protein alterations predisposing the newborn to obesity.

SDN Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02352267

Strategies To Improve Human Cardiac Stem Cell Regenerative Capacity In Patients With Post‐Ischemic Left Ventricular Remodelling



RF‐2011‐02350353

Genetic, immunologic and viral determinants of HIV‐1 disease progression

Lombardia Biomedical AIDS and Related Research 22Infection and immunity

Pagina 190 di 231



SCORE.


STRATEGICA

RF‐2011‐02352275

Nanomaterials‐based diagnostic devices for melanoma

I.E.O. Clinical Bioengineering Sciences and Technologies

22Oncology

RF‐2011‐02351799

Cerebral blood flow velocity in children with sickle cell disease before and after

adenotonsillectomy

Emilia‐Romagna Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02348343

CHILDHOOD HISTIOCYTOSES: FROM PATHOGENESIS TO TARGET THERAPY ‐ "HISTIOCARE"


RF‐2011‐02352215

Inflammatory bowel diseases and environmental stressors: a system biology approach

Campania Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02347100

EFFECTS OF PERIPHERALLY ADMINISTERED BDNF IN THE R6/2 MOUSE MODEL OF HUNTINGTON¿S DISEASE



RF‐2011‐02352448

Humanization of Emergency Departments in Hospitals: new features and patient satisfaction for chronic metabolic and cardiovascular diseases



RF‐2011‐02350451

Role of deubiquitinases in resistance to treatment of ovarian carcinoma


RF‐2011‐02352271

Search for cancer‐specific proteomic biomarkers in exosomes and red blood cells to rule out lung cancer risk in suspicious incidental nodules detected by imaging techniques


Pagina 191 di 231



SCORE.


STRATEGICA

RF‐2011‐02350225

IDENTIFICATION OF NEW STRAINS OF POTENTIALLY PROBIOTIC BACTERIA FROM HUMAN FECES AND FOODS: SUBSEQUENT INVESTIGATION OF THEIR ACTIVITY ON THE BROKERS OF THE SYSTEMIC AND INNATE IMMUNE SYSTEM. POSSIBLE USE OF THE ISOLATE STRAINS ALSO AS DELIVERY SYSTEM FOR


RF‐2011‐02350511

Realization of a database of clinical data for improving the outcome of the univentricular heart patient

ISS Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02351958

Prematurity and low weight at birth as new conditions predisposing to an increased cardiovascular risk. A human study by means of metabolomics, instrumental cardiology, endothelial progenitor cells evaluation, paralleled by an animal experimental model.

Sardegna Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02348570

Role of CREB protein family members in human lymphoid malignancies

Abruzzo Biomedical Cell Biology 22Oncology

RF‐2011‐02348616

Maternal exposure to ENMs: a comprehensive study of feto‐placental effects as a function of developmental stage.



RF‐2011‐02350727

Molecular determinants of malignancy, invasiveness and response to therapy of Oro‐pharyngeal squamous cell carcinomas. A molecular and Redox proteomics compaative analysis of HPV positive and HPV negative invasive tumours.


Pagina 192 di 231



SCORE.


STRATEGICA

RF‐2011‐02350421

Restoring innate immunity by in vivo gene editing: Development of novel approaches to correct abnormal cilia motility in the respiratory airways and cure the primary ciliary dyskinesia in pediatric patients

Toscana Biomedical Genes, Genomes and Genetics 22,25Infection and immunity

RF‐2011‐02352603

SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) BASED DIAGNOSTIC KIT DEVELOPMENT FOR LEUKEMIA BIOMARKER DETECTION

SAN RAFFAELE Milano Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02352734

A MULTIMODALITY APPROACH TO PREVENT POSTOPERATIVE NEUROLOGICAL DYSFUNCTION IN PATIENTS UNDERGOING CARDIAC SURGERY



RF‐2011‐02350763

Identification of molecular signature in thyroid carcinoma to improve Fine Needle Aspiration Biopsy Accuracy


RF‐2011‐02346918

Influence of Zinc transporters on glycemic control and cardiovascular risk prevention



RF‐2011‐02350430

Creation and Preclinical validation of stem cell‐functionalized bio‐substitutes for oral bone defects treatment



RF‐2011‐02350465

Renal stress Echo: a new non invasive non ionizing imaging tool to assess renal sympathetic activity in arterial hypertension and cardiometabolic disease



Pagina 193 di 231



SCORE.


STRATEGICA

RF‐2011‐02350444

Role of maternal intrapartum antibiotic prophylaxis on neonatal gut microbiota flora and onset of later allergy related diseases

Lombardia Biomedical Immunology 22,5Infection and immunity

RF‐2011‐02351129

Process modelling as a tool to support integrated care pathway implementation in

lung cancerpatients.

Friuli‐Venezia Giulia Clinical Healthcare Delivery and Methodologies

22,5Oncology

RF‐2011‐02347458

Cardiopulmonary risk and Transplantation Campania Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02347055

Study of orphan muscle diseases with an inflammatory component and identification of novel therapeutic molecules.

SAN RAFFAELE Milano Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02349978

Regulatory and effector T cell populations count during chronic graft versus host disease and extracorporeal photopheresis (ECP): flow cytometric cGVHD activity monitoring.

Lazio Clinical Immunology 22,5Oncology

RF‐2011‐02350734

A mathematical‐experimental model of beta‐amyloid diffusion in Alzheimer disease and its application to early diagnosis




RF‐2011‐02351275

Identification of biological markers as predictors of brain plasticity and indicators of the efficacy of rehabilitation in post‐stroke patients

AUXOLOGICO Biomedical Brain Disorders and Clinical Neuroscience


Pagina 194 di 231



SCORE.


STRATEGICA

RF‐2011‐02349430

Epithelial ovarian cancer: management of advanced stage disease recurrence by an (epi)genomic‐driven approach


RF‐2011‐02348171

Characterization of the microbiome of natural and invasive vector mosquito populations through next‐generation sequencing

IZS Venezie Biomedical Infectious Diseases and Microbiology


RF‐2011‐02349335

SEEKING MOLECULAR BIOMARKERS OF CERVICAL INTRAEPITHELIAL NEOPLASIA PROGRESSION BY MICROARRAY ANALYSIS OF CLONAL CIN3 KERATINOCYTES.

Emilia‐Romagna Biomedical Oncology 2 ‐ Translational Clinical 22,5The new biotechnologies

RF‐2011‐02351470

Health Care Professionals as Second Victims After Adverse Events

Marche Clinical Risk, Prevention and Health Behavior


RF‐2011‐02348299

NEW ANTIFUNGAL THERAPEUTIC STRATEGIES IN NANOMEDICINE



RF‐2011‐02348071

INNOVATIVE EPINEPHRINE (ADRENALINE) FORMULATIONS WITH IMPROVED STABILITY FOR USE IN EMERGENCY SITUATIONS

SAN MATTEO Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02352174

MicroRNA profile in plasma and sputum in the low‐dose CT lung cancer screening trial Italung


RF‐2011‐02348217

Health and Economic Impact of Tobacco Control Policies in Italy


22,5Oncology

Pagina 195 di 231



SCORE.


STRATEGICA

RF‐2011‐02349186

Evaluation of potential presence of heavy metals and nanoparticles in fishes and baby foods

IZS Sicilia Biomedical Risk, Prevention and Health Behavior


RF‐2011‐02352238

Development of a Regional network for the improvement of the operators compliance to the management of the Italian Register of Oncologic Drugs (RFOM) of Italian Medicines Agency (AIFA)


22,5Oncology

RF‐2011‐02352133

Evaluation of the molecular mechanisms and therapeutic efficacy of a new NGF mimetic compound with anti‐apoptotic activity in cardiac and cerebral ischemia/reperfusion (I/R)



RF‐2011‐02348857

ACG4GEO: Integration between "Adjusted Clinical Group" system and Geomedicine for a new vision about the environment health and personal health

Veneto Clinical Population Sciences and Epidemiology


RF‐2011‐02351207

Clinical and genetic study of the predisposition to Renal Cancer in women affected by uterine fibroids and families with Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome


RF‐2011‐02348991

Age‐immunological profile of stable kidney allograft patients as a key to modulate the immunosuppressive therapy

Piemonte Clinical Immunology 22,5Infection and immunity

Pagina 196 di 231



SCORE.


STRATEGICA

RF‐2011‐02351250

Prevention of chronic kidney disease (CKD) progression by hypoxia‐inducible‐prolyl‐hydroxylases (HIF‐PHs) inhibition: role of SIRT1 and autophagy

MAUGERI Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02349666

Attention to memory: mechanisms of competition during memory retrieval in mild cognitive impairment

SANTA LUCIA Clinical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02352688

IDENTIFICATION OF THE GENETIC BACKGROUND ASSOCIATED TO THE IMPAIRMENT OF RENAL TUBULAR INTRACELLULAR MACHINERY FOR ENDOCYTOSED PROTEINS. SELECTION OF NOVEL BIOMARKERS PREDICTING ONSET OR PRGRESSION OF CHRONIC RENAL FAILURE.

Veneto Biomedical Genes, Genomes and Genetics 22,75The new biotechnologies

RF‐2011‐02350877

Economic Impact of Target Agents and their Side Effects


RF‐2011‐02351910

Physical Activity prevents the Cognitive Impairment in the Metabolic Syndrome (PACIMeS)

SANTA LUCIA Biomedical Risk, Prevention and Health Behavior


RF‐2011‐02351189

Multidisciplinary Intervention Protocol in metabolic emergencies in Anorexia Nervosa



RF‐2011‐02350312

Prospective study of molecular prognostic and predictive factors and pharmacokinetic

analysis in patients with Gastrointestinal Stromal Tumor treated with targhet therapy


Pagina 197 di 231



SCORE.


STRATEGICA

RF‐2011‐02351002

Molecular profiling of adult Acute Lymphoblastic Leukemia for risk stratification and treatment definition

Lombardia Clinical Oncology 2 ‐ Translational Clinical 23Oncology

RF‐2011‐02349965

Ectopic calcifications: from molecular mechanisms towards therapeutic perspectives

Emilia‐Romagna Biomedical Vascular and Hematology 23Metabolism disorders and cardiovascular disease

RF‐2011‐02347947

Impact of early high‐dose atorvastatin versus rosuvastatin on Contrast Induced Acute Kidney Injury in unselected patients with non‐ ST elevation acute coronary syndromes scheduled for early invasive strategy



RF‐2011‐02348619

The impact of the Directive 2010/63/EU on Italian research activities and welfare of

animals

ISS Biomedical Veterinary 23Food safety and animal welfare

RF‐2011‐02350861

Gender effect on the pleiotropic actions of statins on lipoproteins and platelets from elderly women affected by Type 2 diabetes mellitus

I.N.R.C.A. Biomedical Vascular and Hematology 23Metabolism disorders and cardiovascular disease

RF‐2011‐02348791

Role of functional and morphological MRI in the study of thalamus and auditory

cortex for the assessment ofthe neurocognitive and clinical outcomes of

premature newborns



RF‐2011‐02352434

Disability diseases related: (Di.di.re) ICF as tools to weight disability in rehabilitation




Pagina 198 di 231



SCORE.


STRATEGICA

RF‐2011‐02352147

Empower through Communication: a Generative Model for Health‐Care Organizations

NEUROLESI Clinical Healthcare Delivery and Methodologies


RF‐2011‐02349115

Biological and therapeutical significance of androgen receptor expression in salivary gland cancers (SGCs): a translation research in a randomized, international, phase II study to evaluate the efficacy of chemotherapy versus androgen deprivation therapy


RF‐2011‐02352262

Improving reading and behavioural control in dyslexia and ADHD with training on executive functions




RF‐2011‐02352148

Optimal duration of treatment and optimal management of thromboembolic events in cancer patients (Morgagni‐Cancer Study)


Clinical Vascular and Hematology 23Oncology

RF‐2011‐02351224

Sexual function in epileptic male patients NEUROLESI Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02352419

Novel Clinical and Molecular Determinants of Glucocorticoid Response in Obesity‐related Asthma



RF‐2011‐02350950

Development of a model for quantitative risk assessment of tick‐borne diseases in Italian urban parks



RF‐2011‐02348015

Ethics in Cancer Care: a new service I.E.O. Clinical Healthcare Delivery and Methodologies

23Oncology

Pagina 199 di 231



SCORE.


STRATEGICA

RF‐2011‐02348712

Pregnancy complication in transplanted women: anti‐phospholipids antibodies as sensitive biomarkers of prognostic value and pathogenetic determinants.

ISS Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02348514

Hypoxia and MicroRNAs in the Regulation of the Dystrophin‐associated Protein Complex: Implications for Cognitive Deficits in Duchenne Muscular Dystrophy



RF‐2011‐02347575

Update, integration and implementation of the Italian Respiratory Risk Charts



RF‐2011‐02351887

Clinical and genetic new tools for Autosomal Dominant Polycystic Kidney Disease diagnosis



RF‐2011‐02352332

Identification and validation of biomarkers in saliva and scraping of buccal cells for the early detection of oral lesions at risk of developing cancer


RF‐2011‐02350562

Identification of immune correlates of clinical activity and/or disease outcome in melanoma and mesothelioma patients undergoing immunotherapy or targeted therapy

Toscana Clinical Oncology 2 ‐ Translational Clinical 23,5Oncology

RF‐2011‐02347259

STUDY ON THE POTENTIAL USE OF COMBRETUM MICRANTHUM AS AN ANTITUMOR AND CHEMOPREVENTIVE AGENT.



Pagina 200 di 231



SCORE.


STRATEGICA

RF‐2011‐02352339

Understanding sirtuin specificity and identification of selective therapeutics using a trans‐kingdom approach

IDI Biomedical Genes, Genomes and Genetics 23,5Metabolism disorders and cardiovascular disease

RF‐2011‐02349611

Integrated lipidomic profiling in diabetes and cardiovascular disease in a cohort of subjects in a mediterranean area of

southern Italy: a nested case control study

DE BELLIS Biomedical Biological Chemistry and Macromolecular Biophysics


RF‐2011‐02349672

Development and validation of a personal dosimeter for the exposure to electromagnetic fields of Magnetic Resonance healthcare personnel



RF‐2011‐02347335

Innovative analytical methods for determination of veterinary drug residues in foodstuffs


RF‐2011‐02351538

The Mitochondrial culprit in Amyotrophic Lateral Sclerosis: unravelling a novel molecular pathway to regulate VDAC1 in the disease's etiology



RF‐2011‐02350267

Improving the prognosis of melanoma patients through the use of new metastatic markers associated to the Notch pathway.

Lombardia Biomedical Oncology 1 ‐ Basic Translational 23,5Oncology

Pagina 201 di 231



SCORE.


STRATEGICA

RF‐2011‐02352639

Implementation of a network on the use of Human Biomonitoring Data in Environmental Epidemiology (HumanBioEnvEpi: HBEE‐

ITA)Realizzazione di una rete sull¿uso nell¿epidemiologia ambientale dei dati del biomonitoraggio umano (HumanBioEnvEpi: HBEE‐ITA)



RF‐2011‐02350244

Occupational and environmental exposure to dangerous chemicals and reproductive pathologies

Campania Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351311

Cytokine profile in ocular surface diseases and upper airways disorders: development of medical devices for ophthalmology and otorhinolaryngology use.



RF‐2011‐02348939

The Development and progression of breast cancer: when microRNAs fail to inhibit EMT and stemness.


RF‐2011‐02352896

Work‐oriented upper extremity functional evaluation: development of an integrated measurement platform for identification of return‐to‐work strategies



RF‐2011‐02347019

Telemonitoring in long‐term ventilator‐dependent patients: a multicenter randomized controlled study



RF‐2011‐02346746

Extracorporeal Shock Waves (ESW) as a tool in stem cell‐based procedures for cartilage and tendon regeneration



Pagina 202 di 231



SCORE.


STRATEGICA

RF‐2011‐02346933

Identification and use of markers of exposure and effect on decision‐making in patients with metal‐on‐metal joint implants

RIZZOLI Biomedical Healthcare Delivery and Methodologies


RF‐2011‐02347808

Ex vivo studies on hyperhomocysteinemia‐induced epigenetic modifications as potential biomarkers for early diagnosis of cerebrovascular disorders.

Sardegna Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02347984

Biomolecular networks contributing to cancer risk in dysmetabolic disorders: implications for type 2 diabetes and obesity


Biomedical Oncology 2 ‐ Translational Clinical 23,75Metabolism disorders and cardiovascular disease

RF‐2011‐02349526

Effective and genetically‐driven bio‐clinical road map defining tailored, multidisciplinary, treatment strategies of metastatic colorectal cancer (MCRC) patients.

Abruzzo Biomedical Oncology 2 ‐ Translational Clinical 23,75Oncology

RF‐2011‐02352211

CHARACTERIZATION OF BIOMARKERS FOR CARDIOVASCULAR DISEASES AT EARLY PRESENTATION

Veneto Biomedical Biological Chemistry and Macromolecular Biophysics


RF‐2011‐02351881

Identification of novel biomarkers of recurrence in locally advanced cervical cancer


RF‐2011‐02346929

Genetic and environmental factors underlying metabolic inflexibility and their impact for the prevention and treatment of obesity: basic and clinical studies



Pagina 203 di 231



SCORE.


STRATEGICA

RF‐2011‐02348702

GENE EXPRESSION PROFILE AT THE ONSET OF SEVERE CARDIAC FAILURE: IDENTIFICATION AND VALIDATION OF NEW BIOMARKERS

GASLINI Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02352767

Angiogenic pattern as early marker of colon cancer progression. A morphological and immunohistochemical study on colorectal adenomas according to modality of detection.


RF‐2011‐02351490

THE USE OF SENTINEL ANIMALS TO EVALUATE THE ROLE OF ENVIRONMENTAL CHEMICAL POLLUTION IN YOUNG WOMEN WITH BREAST CANCER LIVING IN SINs (NATIONAL iNTEREST SITES)


RF‐2011‐02350789

Biomolecular and Biosensor innovative approaches to guarantee Protected Designation of Origin (PDO) Water Buffalo Mozzarella Cheese


RF‐2011‐02350597

Viral infections and related neurological and intestinal damages as possible factors triggering autism spectrum disorders

Campania Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02349502

Neuronal lifespan in longer living brains SAN MATTEO Biomedical Biology of Development and Aging 24Neurological diseases

Pagina 204 di 231



SCORE.


STRATEGICA

RF‐2011‐02351962

CLINICAL AND ADMINISTRATIVE WORKLOAD: PHYSICIANS WELLBEING, PERFORMANCE AND CONSEQUENCES ON PATIENT SAFETY. COMPARATIVE ANALYSIS AMONG THREE IMPORTANT ACUTE ITALIAN HOSPITALS

Toscana Clinical Risk, Prevention and Health Behavior


RF‐2011‐02348247

Epigenetic modulation by asbestos exposure in asbestos‐related

cancers:identification of epigenetic biomarkers to predict asbestos‐related malignancies.

Marche Biomedical Oncology 2 ‐ Translational Clinical 24Oncology

RF‐2011‐02352297

STRATEGIES TO PROMOTE THE CONTINUOUS IMPROVEMENT OF PATIENT SAFETY AND QUALITY IN HEALTH CARE

Campania Clinical Healthcare Delivery and Methodologies


RF‐2011‐02351310

Ultimate and stable healing of chronic ulcers of the lower limbs with long lasting patient recovery: a great achievement of dramatic social impact with minimal financial commitment.


Clinical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02352167

HELP (Hepatitis and HIV Emergencies, Life & protection Program for drug addicts and immigrants wide range information)

Campania Clinical Infectious Diseases and Microbiology


RF‐2011‐02347601

HIV‐ infected mesenchimal stem cell differentiation: miRNA expression profile and role of antiretroviral therapy

Lombardia Biomedical AIDS and Related Research 24Infection and immunity

Pagina 205 di 231



SCORE.


STRATEGICA

RF‐2011‐02352333

Synthesis of new compounds with antiRET activity and evaluation of their anti‐neoplastic activity (in vitro and in vivo) in papillary and medullary thyroid cancer


RF‐2011‐02347524

Novel tools for immune monitoring and immune reconstitution in children with severely compromised T‐lymphocyte responses associated with hemato‐oncological diseases.


Clinical Immunology 24Infection and immunity

RF‐2011‐02350189

Potential Role of blood miRNA as non invasive biomarkers for early detection of stroke and hemorrhagic transformation



RF‐2011‐02347521

DEVELOPMENT AND VALIDATION OF A COMORBIDITY INDEX SPECIFIC FOR STROKE PATIENTS



RF‐2011‐02347915

ASSESSMENT OF PSYCHO‐PHYSICAL RESPONSE TO STRESSORS IN WORK

ENVIRONMENT. RESEARCH OF CHANGES IN HEALTH PROFESSIONALS AS A RESULT OF PARTICIPATION IN A GROUP EXPERIENCE ON STRESS MANAGEMENT AND INTERPERSONAL COMMUNICATION.

I.N.R.C.A. Biomedical Risk, Prevention and Health Behavior


RF‐2011‐02350130

Prescription of Physical Activity to prevent the onset of type 2 diabetes

Veneto Clinical Risk, Prevention and Health Behavior


Pagina 206 di 231



SCORE.


STRATEGICA

RF‐2011‐02347832

Effectiveness of repeated immunizations with DNA plasmids encoding HER‐2/neu in the long‐term prevention of mammary cancer in HER‐2/neu transgenic mice

I.N.R.C.A. Biomedical Biology of Development and Aging 24Oncology

RF‐2011‐02351175

A simple set of tools for large‐scale multi‐parametric screening of sensory‐motor functions of the cervico‐cranial area. A combined longitudinal and cross‐sectional study in 4‐14 years old children

Piemonte Biomedical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02351350

Reduced aspirin action in preventing cardiovascular events in diabetic patients: molecular and cellular studies on megakaryocyte progenitor cells and platelets.

ISS Biomedical Vascular and Hematology 24Metabolism disorders and cardiovascular disease

RF‐2011‐02349940

Risk stratification of hospital‐acquired infection, an Artificial Neural Network approach



RF‐2011‐02351403

Can we predict the cognitive status in mild cognitive impairment (MCI) subjects who had a traumatic brain injury (TBI) basing on neurophysiological and biological markers?




RF‐2011‐02348748

Identification of immunologic and vascular biomarkers of disease progression or remission in autoimmune disorders for the clinical management and therapeutic monitoring

SAN GALLICANO Clinical Immunology 24,25Infection and immunity

Pagina 207 di 231



SCORE.


STRATEGICA

RF‐2011‐02351123

Comprehensive diagnostic and rehabilitation tools in the assessment and treatment of Neglect dyslexia



RF‐2011‐02352445

Biomarkers of effect as novel tools for the identification of PCB contamination in mussels and their impact on human health.


RF‐2011‐02351012

In vivo safety and tolerability of sorghum based gluten free products in coeliac patients

Campania Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02349298

Early genomic and cellular markers in sporadic colorectal cancer: an integrative methodological approach combining the response of biomarkers in organ biopsies and in a healthy cell system like peripheral mononuclear cells.

Toscana Biomedical Genes, Genomes and Genetics 24,5Oncology

RF‐2011‐02352643

NEOADJUVANT CHEMOTHERAPY AND RADICAL SURGERY IN TREATMENT OF LOCALLY ADVANCED CERVICAL CARCINOMA: 18F‐FDG‐PET/CT AND MOLECULAR BIOLOGY PREDICTIVE VALUE IN EARLY AND LATE ASSESSMENT OF RADICAL SURGERY FEASIBILITY AND ITS SURVIVAL IMPACT

Sicilia Clinical Oncology 2 ‐ Translational Clinical 24,5Oncology

RF‐2011‐02352315

A Randomized Clinical Double Blind Placebo Controlled Study of Human Fecal Microbioma in Irritable Bowel Syndrome Treated with Probiotic and a Boswellia Serrata Gum Extract Tritated in Boswellic

Acids



Pagina 208 di 231



SCORE.


STRATEGICA

RF‐2011‐02351675

Rational and innovative design of immunogens based on HIV‐1 clade C Env proteins specifically mutated in glycan moieties for broadly effective vaccine purpose


RF‐2011‐02348398

Observational population‐based study on ovarian cancer management within the Piedmont Region Cancer Network


24,75Oncology

RF‐2011‐02349233

Directing the axonal outgrowth via magnetic nanoparticles and magnetic fields

for nerve regeneration: a pre‐clinical study

Toscana Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02348441

Lung water assessment by quantitative chest ultrasonography in cardiac surgery patients



RF‐2011‐02349862

Role of miR‐494 and other microRNAs in Src kinase inhibition of colorectal cancer stem cells

Umbria Biomedical Oncology 1 ‐ Basic Translational 25Oncology

RF‐2011‐02347437

Role of HDL and endothelial dysfunctions in modulating the impact of risk factors on sub clinical atherosclerosis in diabetes

Toscana Clinical Vascular and Hematology 25Metabolism disorders and cardiovascular disease

RF‐2011‐02350315

Early detection of chronic obstructive pulmonary disease induced by industrial pollutants by analysis of volatile organic compounds from exhaled breath.

Puglia Clinical Cardiovascular and Respiratory Sciences


Pagina 209 di 231



SCORE.


STRATEGICA

RF‐2011‐02352531

New ultrasonic methods for OSTEOporosis diagnosis at the proximal FEMur (OSTEOFEM)

Puglia Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02348360

Identification of host prion proteins resistant to template‐conversion into PrPSc


RF‐2011‐02350825

Immunological and virological monitoring of opportunistic virus infections in systemic lupus erythematosus patients

SAN MATTEO Biomedical Immunology 25Infection and immunity

RF‐2011‐02350711

Attenuation of the Hippo pathway by praja2 reduce glioblastoma growth

NEUROMED Biomedical Oncology 1 ‐ Basic Translational 25Oncology

RF‐2011‐02352584

Klebsiella Pneumoniae carbapenemases (KPCs) positive strains in hospitalized decompensated cirrhotic patients: a nationwide epidemiologic survey and the evaluation of a new eradication treatment based on faecal‐microbiota transplantation



RF‐2011‐02348365

Genetic and functional analysis for identification of driver pathways of resistance in breast cancer metastases and xenograft obtained from patients with triple negative, HER2 positive and Luminal B subtypes


RF‐2011‐02351730

Efficacy of Etanercept vs Adalimumab in retreating psoriatic patients who previously failed treatment with the same molecule

SAN GALLICANO Clinical Musculoskeletal, Oral and Skin Sciences


Pagina 210 di 231



SCORE.


STRATEGICA

RF‐2011‐02347987

Oxidative stress and microRNA‐125b: from molecular mechanisms to therapeutic

implications in Hailey‐Haileydisease

ISS Biomedical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02352341

ECG IN UN CLIK Lazio Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02350351

Exploitation of genetically engineered oral carcinoma relapse models for development and pre‐clinical assessment of targeted combinatorial therapeutic strategies


RF‐2011‐02348239

A novel anti‐CXCR4 drug RFF‐1: a Phase I/II Clinical Trial


RF‐2011‐02348558

Combined intravenous and intra‐arterial thrombolysis for ischemic stroke due to large vessel occlusion: feasibility, safety and effectiveness.




RF‐2011‐02352027

Protein‐based carriers for targeted photodynamic therapy


RF‐2011‐02351398

Identification of mycobacterial cell surface molecules as molecular markers of disease



RF‐2011‐02347096

Prostate cancer: a study on the mechanisms underlying the development of androgen‐independence to identify early biomarkers and new therapeutic targets


Biomedical Oncology 1 ‐ Basic Translational 25Oncology

Pagina 211 di 231



SCORE.


STRATEGICA

RF‐2011‐02352371

Cardiovascular disease in intrauterine growth restriction (IUGR). A clinical and proteo‐metabolomic investigation.



RF‐2011‐02348938

Sustainable innovation of husbandry practices to improve animal health and welfare and to reduce the use of antimicrobials in broiler chickens


RF‐2011‐02349194

THERAPEUTIC DEVICE OF AREA FOR ADOLESCENTS WITH SEVERE PSYCHIATRIC DISORDERS. INTENSIVE SPECIFIC OUT‐PATIENT SERVICE

Lombardia Clinical Risk, Prevention and Health Behavior


RF‐2011‐02350541

Inflammatory links between obesity, asthma and adaptive immunity in childhood


RF‐2011‐02352703

Contribution of the different risk factors to the prevalence of gestational diabetes

mellitus. A cohort study.

Emilia‐Romagna Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02351519

Toxic and infective agents as potential cause of congenital malformations of domestic ruminant calves in southern Italy.

IZS Mezzogiorno Biomedical Veterinary 25,5Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02351639

Effectiveness of oncology drugs of AIFA Oncology Register



Pagina 212 di 231



SCORE.


STRATEGICA

RF‐2011‐02351772

An economic, randomized, prospective phase III trial comparing the combination of anthracycline‐taxane vs bevacizumab‐paclitaxel as first‐line treatment in women with HER‐2 negative metastatic breast cancer

REGINA ELENA Clinical Oncology 2 ‐ Translational Clinical 25,5Oncology

RF‐2011‐02352481

Study of the selectivity of botulinum toxins (BoNT‐A and BoNT‐C) for muscle fiber type units and their kinetics diffusion by exo‐endocytosis: electro and impedence myography evaluation, biochemical pathway analysis and possible clinical implication in Sp

Toscana Biomedical Molecular, Cellular, and Developmental Neuroscience


RF‐2011‐02352676

Genetic Polymorphisms and pain sensitivity in a Sicilian population of oncological patients


RF‐2011‐02351862

Ecological and biomolecular studies on Culicoides for an innovative approach to the control of Culicoides transmitted diseases

IZS Sicilia Biomedical Infectious Diseases and Microbiology


RF‐2011‐02349501

FISH FARMING AND WELFARE: ASSESSMENT OF ACOUSTIC, THERMAL AND CHEMICAL STRESS FOR A MORE AQUACULTURE SUSTAINABLE



RF‐2011‐02347868

Novel clinical applications of autologous adipose‐derived stem cells.

Emilia‐Romagna Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering


Pagina 213 di 231



SCORE.


STRATEGICA

RF‐2011‐02351472

Influence of cell‐cell adhesion molecules expression on the metastatic growth of colon cancer stem cells in liver.

ONCOLOGICO DI BARI Biomedical Oncology 1 ‐ Basic Translational 26Oncology

RF‐2011‐02349688

ASSISTENTIAL AFTERMATH OF DISTRESS IN MATERNIY WARD PROFESSIONALS FACING MISCARRIAGE, STILLBIRTH AND PERINATAL GRIEF



RF‐2011‐02350933

ANALYSIS OF ADIPONECTIN SYSTEM AS NEW TARGET FOR DIAGNOSIS AND THERAPY OF CHRONIC OBSTRUCTIVE PULMONARY PATIENTS WITH COEXISTENT CARDIOVASCULAR DISEASE

SDN Biomedical Cardiovascular and Respiratory Sciences


RF‐2011‐02350396

Nanoparticles as drug delivery system for the therapy of Mesothelioma and Pancreatic Cancer.


RF‐2011‐02347343

COCAINE AND CHEST PAIN Emilia‐Romagna Clinical Risk, Prevention and Health Behavior


RF‐2011‐02347163

The anatomical substrate of unilateral neglect subtypes: behavioral and neuroimaging investigation

S.CAMILLO Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02352675

SURVEILLANCE OF THE PREVALENCE OF PERIODONTITIS AND CHARACTERIZATION OF MICROBIOLOGICAL PROFILE IN A REPRESENTATIVE ADULT ITALIAN POPULATION.



Pagina 214 di 231



SCORE.


STRATEGICA

RF‐2011‐02348102

BLeeding Events and Maintenance DoSe of PraSugrel.



RF‐2011‐02348298

Functional Imaging and Transcriptomics for Prediction of Ovarian cancer response

to Trabectedin


RF‐2011‐02350324

A GENETIC, CLINICAL AND SOCIAL INVESTIGATION OF DEMENTIA IN NORTH‐EASTERN ITALY



RF‐2011‐02352110

Innovative biomarkers for oxidative stress in diabetic retinopathy: evaluation of curcumin inhibition.

BIETTI Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02348357

Natural history of circulating Endothelial Progenitor Cells in aging of healthy subjects and during vascular injury progression in patients with type 1 diabetes. Validation of the role of circulating Endothelial Progenitor Cells as a novel paradigm of Ca

Toscana Clinical Vascular and Hematology 26Metabolism disorders and cardiovascular disease

RF‐2011‐02352575

Omics study of competitive action of starter add on fresh meat production (italian salami) to improve safety

Abruzzo Biomedical Infectious Diseases and Microbiology


RF‐2011‐02351967

Impact of Atorvastatin Use on Death or clinical Events Occurrence among HIV‐1 infected patients without hyperlipidemia. AUDEO Study

SAN RAFFAELE Milano Clinical AIDS and Related Research 26Infection and immunity

Pagina 215 di 231



SCORE.


STRATEGICA

RF‐2011‐02348367

IDENTIFICATION AND ANALYSIS OF MOLECULAR ALTERATIONS IN ENDOTHELIAL CELLS DERIVED FROM CEREBRAL CAVERNOUS MALFORMATIONS

NEUROLESI Biomedical Brain Disorders and Clinical Neuroscience


RF‐2011‐02350900

Chest pain in the Emergency Department : the role of diabetes, dyslipidemia and obesity in the incidence of ACS in population with/without a history of CAD. Mortality, reinfarction and survival related factors


Clinical Population Sciences and Epidemiology


RF‐2011‐02350590

Infective exacerbations of COPD, comorbidity and gender differences

Puglia Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02351973

Burden of disease of work related asthma Toscana Biomedical Population Sciences and Epidemiology


RF‐2011‐02348491

Effects of peripheral sensory pressure stimulation on the cardiovascular autonomic profile, inflammatory state and movement disorders in patients with Parkinson's disease: evaluation of the time course and underlying neurophysiological mechanisms. A new c

HUMANITAS Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02351114

Role of autophagy and cell oxidation in Hungtinton Disease (HD)



RF‐2011‐02352033

Developing a Nutritional genomics approach for the prevention of Colon cancer


Pagina 216 di 231



SCORE.


STRATEGICA

RF‐2011‐02350612

DEACETILASE INHIBITORS AS NEW TOOLS TO CONTROL LOCAL INVASION AND METASTASIS OF ENDOCRINE‐RELATED TUMORS


RF‐2011‐02350897

Primary cancer cells as models to test new drugs and to personalize the therapy

Campania Biomedical Oncology 2 ‐ Translational Clinical 26,5Oncology

RF‐2011‐02352409

Analysis of myocardial function after aortic valve replacement with a novel sutureless

valve: coupling mathematical modelsto clinical research.

Sicilia Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02349742

DEVELOPMENT OF LABORATORY PROCEDURES TO ASSESS BIOFILM PRODUCTION AND DRUG RESISTANCE OF BIOFILM‐FORMING BACTERIA FOR NOSOCOMIAL SURVEILLANCE AND THERAPEUTIC MANAGEMENT

SAN GALLICANO Clinical Infectious Diseases and Microbiology


RF‐2011‐02350096

Prevention of nosocomial Legionnaires' disease: use of spoligotyping in evaluating L. pneumophila susceptibility to chlorine and monochloramine.



RF‐2011‐02351388

Prevention of restenosis after percutaneous transluminal angioplasty (PTA)

MULTIMEDICA Clinical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02349028

Intensive vs non‐intensive rehabilitation program in Parkinson's disease (PD) patients. Study for evaluating a non invasive approch to increase neurotrophic factors in the brain of PD patients.



Pagina 217 di 231



SCORE.


STRATEGICA

RF‐2011‐02349070

Mens sana in corpore sano? The impact of multi‐year exercise on physical and mental health at different ages.



RF‐2011‐02351963

The oral modifications in very early and established Systemic Sclerosis

Toscana Clinical Musculoskeletal, Oral and Skin Sciences


RF‐2011‐02351137

Pathophysiology of central fatigue in patients with multiple sclerosis: an integrated neurophysiologic and neuroimaging approach.

NEUROLESI Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02350962

Efficacy of Magnetic Fields stimulation for the treatment of human gastric cancer associated, or not, to pathogen Helicobacter pylori infection.


RF‐2011‐02347336

Multi‐disciplinary approach to predict adverse ventricular remodeling in post‐MI patients: combined evaluation of cardiac dysfunction and immune‐related biomarkers after revascularization procedure



RF‐2011‐02348957

Application of optical nanoplasmonic biosensors as a complementary tool for the early detection of Legionella spp in water systems. (NANOBIOLEG)

Puglia Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02352658

Hospital Procedures for acute heart failure and integrated country/hospital healthcare



Pagina 218 di 231



SCORE.


STRATEGICA

RF‐2011‐02348613

MELATONIN LOADED NANOPARTICLES FOR POSTNATAL TREATMENT OF CEREBRAL PALSY IN A RAT MODEL



RF‐2011‐02351482

Randomised Controlled Trial on lifestyle impact on health outcomes in the general population invited to mammography and colorectal cancer screening programmes.

Piemonte Biomedical Risk, Prevention and Health Behavior

27Oncology

RF‐2011‐02351751

Incidence and outcome of ocular infections caused by multi drug‐resistant microorganisms in intensive care unit patients: clinical, epidemiological and therapeutic management.



RF‐2011‐02352213

Human defensins: a new weapon or an old enemy?

Campania Biomedical Immunology 27Infection and immunity

RF‐2011‐02348453

Primary Central Nervous System Vasculitis in the Young. A diagnostic and follow‐up study using 7‐Tesla MRA.



RF‐2011‐02348524

Effect of stress ( and psychological factors) on immune and endocrine systems in patients affected by breast carcinoma and hormone‐correlated tumours.

I.N.R.C.A. Clinical Biobehavioral and Behavioral Processes

27Oncology

RF‐2011‐02347802

Genetic characterization of Non‐Small‐Cell Lung Cancer (NSCLC) to evaluate intratumor heterogeneity and modification after Tyrosine Kinase Inhibitors' (TKI) failure

C.R.O. AVIANO Clinical Oncology 1 ‐ Basic Translational 27Oncology

Pagina 219 di 231



SCORE.


STRATEGICA

RF‐2011‐02347109

Role of growth hormone‐releasing hormone (GHRH) in cardiac hypertrophy



RF‐2011‐02350540

Palitoxins: toxicity studies and development of new rapid methods of detection



RF‐2011‐02350552

Eating disorders and risk factors for metabolic and cardiovascular diseases. A follow‐up study after ten years from the initial diagnosis

Emilia‐Romagna Clinical Biobehavioral and Behavioral Processes


RF‐2011‐02352574

Lab‐on‐chip technology and new clinical application



RF‐2011‐02352150

Molecular pathogenetic mechanisms and prognosis of sinonasal adenocarcinomas in relation to occupational exposure

Piemonte Clinical Oncology 2 ‐ Translational Clinical 27Oncology

RF‐2011‐02352159

Chemical, biological, and clinical characterization of silver delivery systems for burns treatment



RF‐2011‐02351769

Randomized Controlled Trial on the efficacy of LLLT (Low Level Laser Therapy) in combination with standard treatment, in preventing and treating chemo/radiotherapy‐induced oral mucositis in head and neck cancer patients and in hematologic neoplasms patien



27,5Oncology

RF‐2011‐02349644

Molecular and cellular correlates of vitamin D‐ dependent antimicrobial activity in an

ovine model of local immunefunctions

IZS Sardegna Biomedical Veterinary 27,5Infection and immunity

Pagina 220 di 231



SCORE.


STRATEGICA

RF‐2011‐02350322

Titanium‐based third generation biomimetic scaffolds for bone tissue regeneration

SAN MATTEO Biomedical Bioengineering Sciences and Technologies


RF‐2011‐02349254

Copayment and compliance to the diagnostic therapeutic pathways

AGENAS Clinical Healthcare Delivery and Methodologies


RF‐2011‐02350354

Endothelial progenitor cells, cardiovascular health and longevity.A prospective study

in centenarians and their offspring from Marche.

I.N.R.C.A. Biomedical Biology of Development and Aging 27,5Metabolism disorders and cardiovascular disease

RF‐2011‐02350822

Gold compounds, potential anticancer agents with an innovative mode of action: mechanistic studies and in vivo evaluation


RF‐2011‐02349709

Pulmonary Embolism: diagnosis, treatment, management and outcomes in a general hospital with a fully computerized information system.

Lombardia Clinical Cardiovascular and Respiratory Sciences


RF‐2011‐02350982

Incidence, persistence and clearance of anal Human Papillomavirus infection in a cohort of immunocompetent and immunocompromised males: a longitudinal study.

SAN GALLICANO Biomedical Infectious Diseases and Microbiology


RF‐2011‐02352696

Endocannabinoid system and Human Ovarian Tumors


Pagina 221 di 231



SCORE.


STRATEGICA

RF‐2011‐02351992

Early detection of the onset of potential risk in order to counteract and to prevent their spread. An introduction of an advanced computer system that, with a right level of automation, collect information available on the internet to monitor their conten

IZS Lazio e della Toscana Biomedical Veterinary 28Food safety and animal welfare

RF‐2011‐02348737

Comparative Effectiveness of dual antiplatelet therapy after acute coronary syndromes



RF‐2011‐02350619

Myocardial Infarction in Low Risk Patients: Integrating Risk Assessment with Tissue Biomarkers and Metabolomics



RF‐2011‐02349566

Randomized controlled study for the implementation of a new interprofessional model for the management of palliative care in oncological patients


28Oncology

RF‐2011‐02348650

Genetic response of colorectal carcinoma to chemotherapy to predict tumor response and circumvent chemoresitance


RF‐2011‐02349043

IMPROVING THERAPEUTIC RESPONSES IN MELANOMA THROUGH THE COMBINATION OF TARGET AND IMMUNOLOGIC THERAPIES: AN IN VITRO AND IN VIVO STUDY


RF‐2011‐02351995

Facing dourine challenge: improvement of diagnostic tools and investigation of pathogenic mechanisms


Pagina 222 di 231



SCORE.


STRATEGICA

RF‐2011‐02349431

Hemoglobin A1c (HbA1c) levels and early markers of cardiovascular disease: identification of cardiometabolic risk in pre‐

diabetic subjects.



RF‐2011‐02349667

IMPLEMENTATION AND ASSESMENTOF AN ORGANIZATIONAL SIMULTANEOUS

CARE MODEL


RF‐2011‐02348745

Implementation of reading/writing learning method called "Globalismo Affettivo" in

children with Neuropsychiatric Disorders

Puglia Clinical Brain Disorders and Clinical Neuroscience


RF‐2011‐02351877

Effects of Mirror Visual Feedback Therapy (MVFT) in neuropathic pain syndromes. Possible role played by sensory‐motor cortical reorganization evaluated by 3T‐fMRI.

MAUGERI Clinical Integrative, Functional, and Cognitive Neuroscience


RF‐2011‐02349135

A new kinkless polyurethane‐silicone vascular graft implanted as femoropopliteal bypass for ischemic limb salvage: a pilot clinical study.

Emilia‐Romagna Biomedical Surgical Sciences, Biomedical Imaging, and Bioengineering


RF‐2011‐02349540

Design and implementation of a national network for remote identification of parasite arthropodes.


RF‐2011‐02352016

Healthcare Associated Infections and Automated Area Decontamination: a challenge for the intended application, the evidence base for effectiveness, affordability of implementation and cost constraints



Pagina 223 di 231



SCORE.


STRATEGICA

RF‐2011‐02352755

Detection and molecular characterization of Cryptosporidium, Giardia and Toxoplasma oocysts/cysts in bivalve mollusks destined for human consumption.

IZS Sardegna Biomedical Veterinary 29Food safety and animal welfare

RF‐2011‐02351516

Improving therapeutical potential of histone deacetylases inhibitors in non‐small

cell lung cancer


RF‐2011‐02349424

Transcranial Magnetic Stimulation in alcohol dependence



RF‐2011‐02350797

Building of MM associated vascular niche to dissect MM‐endothelial cells dialogue


RF‐2011‐02352326

Complementary and Alternative Medicine for the treatment of chronic pain: a pilot study

NEUROLESI Clinical Biobehavioral and Behavioral Processes


RF‐2011‐02352441

CHLORPYRIFOS, DELTAMETRIN AND DIAZINON, A REAL RISK FOR ANIMAL

AND HUMAN HEALTH. EVALUATION OF GENOTOXICITY, OXIDATIVE STRESS, HORMONAL AND TISSUTAL RESPONSES IN FISH EXPERIMENTALLY EXPOSED TO PESTICIDES



RF‐2011‐02352208

Enhancing and monitoring indoor and outdoor physical activity and its intracellular and quality of life effects in type 2 diabetic patients

Lombardia Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


Pagina 224 di 231



SCORE.


STRATEGICA

RF‐2011‐02351721

Interactions between Circulating Tumor Cells (CTCs) and the hepatic microenvironment in human metastatic colorectal cancer: The ADAM‐9 protein as a target for tumor/stromal therapy.

DE BELLIS Biomedical Oncology 1 ‐ Basic Translational 29,5Oncology

RF‐2011‐02352240

Melanoma and non‐melanoma skin cancer: anatomic site, sun exposure, predictive and prognostic biomarkers

SAN GALLICANO Clinical Oncology 1 ‐ Basic Translational 29,5Diseases of environmental origin, with reference also to the workplace

RF‐2011‐02348303

Hypermethylation and downregulation of IRX1 gene induced by Helicobacter pylori infection: etiopathogenetic role in gastric cancer development, prognostic impact after surgical resection and diagnostic employment as screening test


RF‐2011‐02352557

Proteomic profiling of hematological malignancies by Reverse Phase Protein Array: an innovative traslational approach to identify biomarkers for prognosis and molecular therapy.

Lazio Biomedical Oncology 2 ‐ Translational Clinical 29,5Oncology

RF‐2011‐02349136

FROM REMOTE MONITORING TO REMOTE CARE: IMPACT ON CLINICAL AND MANAGEMENT ISSUES OF AN INTEGRATED APPROACH TO FOLLOW HEART FAILURE PATIENTS WITH IMPLANTABLE CARDIAC DEVICES.



Pagina 225 di 231



SCORE.


STRATEGICA

RF‐2011‐02351764

Zoonotic risks assessment of the handling and consumption of meat from main wild ungulates (wild boar/Sus scrofa, roe deer/Capreolus capreolus) hunted in Nord Italy (Aosta Valley Region) and South Italy (Calabria Region)



RF‐2011‐02348870

From psycho‐social stress to immuno‐mediated dermatoses (vitiligo and psoriasis): a molecular approach.


RF‐2011‐02352200

Definition of an Integrated Risk Assessment of Health Care Worker Biomechanical Musculoskeletal Overload



RF‐2011‐02347189

BEVO SIRCOPANOS (endocrine Benefits from Sicilian Extra Virgin Olive Oil, Sicilian Red wine and Consumption of Pesce Azzurro but No Smoking): a project by the Program of Molecular & Clincical Endocrinology and Women's Endocrine Health.

Sicilia Clinical Endocrinology, Metabolism, Nutrition and Reproductive Sciences


RF‐2011‐02350672

Clinical implications of gene polymorphism (TAAA)n of sex hormone‐binding globulin in breast cancer patients with or without hormone‐therapy.

ONCOLOGICO DI BARI Biomedical Genes, Genomes and Genetics 30Oncology

RF‐2011‐02348251

MICROENVIRONMENT INFLUENCE ON CANCER STEM CELL DEVELOPMENT

Veneto Biomedical Oncology 1 ‐ Basic Translational 30Oncology

Pagina 226 di 231



SCORE.


STRATEGICA

RF‐2011‐02351819

Role of LXR alpha and related target genes in the pathogenesis of atherosclerosis. Evaluations in patients with different stages of atherosclerotic disease.



RF‐2011‐02352656

MECHANOTRANSDUCTION FOR THE TREATMENT OF OSTEOPOROSIS: MECHANISM OF ACTION, PRECLINICAL AND CLINICAL EFFICACY OF EXTRACORPOREAL SHOCK WAVES (ESW) FOR THE PREVENTION OF PATHOLOGICAL FEMORAL NECK FRACTURES



RF‐2011‐02348580

A translational medicine research collaboration to fight preeclampsia: from molecular pathogenesis to biomarkers of the disease and novel treatments



RF‐2011‐02347348

Validation of Augmented Reality Navigation for HIFU Treatments


31Oncology

RF‐2011‐02352659

Production of honey‐based materials from Italian honey and their application in medicine and surgery



RF‐2011‐02350800

Short term cultures of surgical tissue slices to evaluate the sensitivity of breast cancer subtypes to the anti‐tumor effects of all‐trans retinoic acid and derived retinoids: identification of the cellular and molecular determinants



Pagina 227 di 231



SCORE.


STRATEGICA

RF‐2011‐02351015

Realization of a protocol for the rapid identification of etiological agent/s responsible for sepsis directly from peripheral blood of septic subjects, by integration of molecular biology, mass‐spectrometry and classical methods.



RF‐2011‐02348864

Outcome of Rehabilitation in an experimental Hospital garden: a prospective, quasi‐experimental study on a sample of subacute stroke patients.



RF‐2011‐02352268

Study of bio‐molecular and immunological mechanisms of response and resistance to targeted therapy (antiBRAF, antiMEK, or both) in patients with metastatic melanoma


RF‐2011‐02352651

SOW Project: safety on work. An intervention to increase attention of workers, making them aware of risky behavior in psychoactive substances consumption.

Campania Clinical Risk, Prevention and Health Behavior


RF‐2011‐02352083

Colorectal cancer stem cells, microenvironment and improved diagnosis for potential therapy


RF‐2011‐02347172

Risk maps of MAP (Mycobacterium avium subsp. paratuberculosis) using advances

technologies

IZS Lazio e della Toscana Biomedical Veterinary 31,5Infection and immunity

Pagina 228 di 231



SCORE.


STRATEGICA

RF‐2011‐02350865

Colorectal carcinogenesis: Study, in vivo and in vitro, of the molecular mechanisms of cell differentiation of the human colon

cancer cells


RF‐2011‐02352731

Aerobiological monitoring and allergy management in Abruzzo

Abruzzo Biomedical Risk, Prevention and Health Behavior


RF‐2011‐02347025

Amniotic stem cells to improve congenital kidney damage: a fetal lamb model

SAN MATTEO Biomedical Digestive, Kidney and Urological Systems


RF‐2011‐02352822

Development and performance evaluation of different assays for the study of the presence of viable Toxoplasma gondii in vegetable and meat



RF‐2011‐02349284

Dissecting the role of chronic stress and its consequences on tumor growth and

metastasis in animal models


RF‐2011‐02346768

Population‐based active surveillance of acute HIV infection.

SAN MATTEO Clinical AIDS and Related Research 32,5Infection and immunity

RF‐2011‐02352237

Link between clinical features of haematological patients, molecular and cytofluorimetric data: WT1 and relationship with other markers.

Basilicata Clinical Oncology 2 ‐ Translational Clinical 32,5Oncology

RF‐2011‐02350876

Mechanisms and actions of Regorafenib (Stirvaga), a new hepatocarcinoma (HCC) therapy


Pagina 229 di 231



SCORE.


STRATEGICA

RF‐2011‐02352618

Estimate of breast cancer risk in relation to mammographic density by using a software for automatic evaluation of the density.


33Oncology

RF‐2011‐02350793

Evaluation of the immune response against Mycobacterium avium subsp.

paratuberculosis in humans and animals

IZS Umbria e delle Marche Biomedical Veterinary 33,5Infection and immunity

RF‐2011‐02350079

Asbestos dosage in biological tissues and fluids: standardization of sample preparation and analytical methods within National Health Service, Universities and Regional Environmental Protection Agencies laboratories.


RF‐2011‐02347545

Circulating microRNAs as novel biomarkers for Amyotrophic Lateral Sclerosis



RF‐2011‐02352609

AN ITALIAN REGISTER OF NEONATAL EPILEPTIC ENCEPHALOPATHY



RF‐2011‐02350437

Application of nanomechanical assays to detection of algal toxins


RF‐2011‐02347424

The integrated and multi‐disciplinary management of patients with peripheral arterial disease and lower limbs trophic lesions: improving adherence and quality of life

Sicilia Clinical Risk, Prevention and Health Behavior


RF‐2011‐02352480

Sexual dysfunction after Traumatic Brain Injury and consequences on couple relationship: assessment and treatment.



Pagina 230 di 231



SCORE.


STRATEGICA

RF‐2011‐02351074

Direct management of litigation: a real chance to improve the Italian National Health System



Pagina 231 di 231

ministero della salute … · characterization of novel disease genes carlo besta biomedical genes,...

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