mirc for nih research consortia inforad, rsna, 2004 john pearson, ph.d. siemens corporate research...
TRANSCRIPT
MIRC for NIH Research Consortia
InfoRad, RSNA, 2004
John Pearson, Ph.D.Siemens Corporate Research
Princeton, NJ
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Introduction: MIRC for NIH Research “Networks”• New U54 Program Announcements establish multi-institutional,
inter-disciplinary consortia• Consortia are formed to pool expertise, validate approaches,
forge common instrumentation platforms, and rapidly translate promising new medical imaging technologies toward clinical trials.
• One such consortia is the “Breast Cancer Diffuse Optical Imaging” (BCDOI) network, sponsored by the NCI’s “Networks for Translational Research: Optical Imaging” (NTROI). – 5 year, $18M program started Sept. 2003– UCI (B. Tromberg, PI), MIT/MGH, Dartmouth, UPENN, SCR, U. Illinois, NIH
• This talk introduces the BCDOI’s plans for developing a MIRC-based infra-structure to support multi-institutional imaging research
• Our extensions to MIRC, called C-MIRC (“C” for “Collaboration), will be made in a general way to support multi-institutional imaging research projects
• The spirit of C-MIRC is to provide a “Collaborative Lab Notebook” to enable the multi-institutional team to function as a seamless organization – we invite your suggestions!
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C-MIRC Hierarchical Data Representation
Program
Project
Experiment
Subject
Study
Series
Data
The Data can be in many formats and containers, including DICOM/PACS, but also unstructured documents – whatever is convenient to the researcher.
(e.g., Multimodal Fusion)
(e.g., MR/Optical Fusion, or Tomosynthesis/Optical Fusion)
(e.g., MR/Optical with UPENN imager using ICG contrast)
Research Category Levels
Data Levels
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PACS
Files
Centralized Management of Metadata, Forms, User Accounts, Distributed Local Storage of Data
Forms,Users,
Metadata
PACS
Files
FilesPACS
FilesLabData
PACSPACSLab
Data
Dartmouth UPENN
UCI
SCR
Secure Connection
Links toImage/Lab
Data
Links toImage/Lab
Data
MIT-MGH
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C-MIRC Service Overview
C-MIRCC-MIRC
C-MIRC
C-MIRC
C-MIRC
Data Exchange via XMLover the InternetExperiment
Submit
MIRC Core Services
ExperimentCollection
TreeStorage
TreeQuery
CollaborativeNotification
ComputePlugins
CLN: Collaborative Lab Notebook
Metadata
CLN Specific Services
MIRC Extension Services
CLNIntegrated
Bulletin Board
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Enter Username and Password to logon to the system.
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„Where Am I“ Navigation within HierachyRecent Messages and tasks pending.
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List of Experiments we can currenty access
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We can link data to a Study be selecting a PACS.
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Browse the PACS structure and add pictures.
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We want to searchfor some data at the C-MIRC at UPENN.
Select UPENN fromThe listbox in theProgram tab
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We want to searchfor some data at the C-MIRC at UPENN.
Select UPENN fromThe listbox in theProgram tab
To see which projects there are within this program click the Project Tab
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There are currentlyonly two projects at UPENN.
We select the DOT/MR Fusion Project ...
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There are currentlyonly two projects at UPENN.
We select the DOT/MR Fusion Project ...
... And hit the search button.
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As a result we get the records found as a tree.
To make the tree simpler, we can change the hierachy level to Experiment.
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Now the tree starts with the Experiment.
By clicking on Listview we get a list of all Experiments (Hierachy Level).
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This Project contains one Expertiment.By Clicking on the Experiment, we get the Subjects below.
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This Experiment contains two Subjects. Notice, that the Hierachy chanced to Subject.
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Next Steps
• Sept 2004: Project started• Currently refining user interface concepts and data
architecture with university partners• Jan 2005: First MIRC system deployed to “get feet wet”• June 2005; First C-MIRC deployed to UPENN• Oct 2005: begin deploy C-MIRC to all consortia members,
expand functionality based on feedback during the next year.
• We welcome your feedback!
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MIRC Extension Service
• Tree Query Service: Enables MIRC users to query data stored within NOMIC systems.
• Tree Submit Service: Enables MIRC users to place MIRC documents within the tree structure of NOMIC.
• Smart Notification Service : Send Messages in relation to information stored in a NOMIC system.
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NOMIC Sample Experiment Data
Program
Project
Experiment
Subject
Study
Series
Data
Breath Caner Vaccines
Caner Vaccines
Vaccine HER-2 on Residual DNA
Andrea, Johnson; 09/10/1978 ..Study Attribute Data
Date 7/14/2004; 11:00
Type of Device Frequ. Domain
Frequency 100 – 400
Sources 8
Power (mW) 10
Detectors 16
Wavelength 6
... ...
Series Attribute Data
Scan Time 1 sek
Detector Separation
2, 4, 6
Source Separation
4
Hb +2uM
HbO2 -1 um
H2O OK
Lipid + 10 %
... ...
Lab Attribute Data
Solution Time (h) 4
Sensor Tissue Direct
Pressure 300
Breast Diameter 10
A priori data MRI
Beacon LDL Receptor
Fluorochome Cy 5,5
... ...
Callibration Data
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NOMIC Functionality Overview
• Use RSNA MIRC multi-site web technology for sharing, distributing and collecting medical experiment data
• While NOMIC focuses on the experiment hierarchy model, MIRC focuses on the teaching document model. They have shared data elements.
• NOMIC will function as a collaboratory lab notebook (CLN) to support experiment submission, query and collection among multiple NOMIC sites
• NOMIC can exchange experiment records over the internet using MIRC based XML Schema
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CLN Specific Services
• Experiment Submit Service: Link data from PACS/FTP/File Servers to RDBMS.
• Experiment Collection Service: Automatic collecting experitment data from multiple NOMIC sites; The output forms of collected data will be based on format criteria such as Excel and CVS
• CLN Plugin Service: Interface for advanced lab data online analysis.