mirc for nih research consortia inforad, rsna, 2004 john pearson, ph.d. siemens corporate research...
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MIRC for NIH Research Consortia InfoRad, RSNA, 2004 John Pearson, Ph.D. Siemens Corporate Research Princeton, NJ Slide 2 S I E M E N S C O R P O R A T E R E S E A R C H Introduction: MIRC for NIH Research Networks New U54 Program Announcements establish multi-institutional, inter-disciplinary consortia Consortia are formed to pool expertise, validate approaches, forge common instrumentation platforms, and rapidly translate promising new medical imaging technologies toward clinical trials. One such consortia is the Breast Cancer Diffuse Optical Imaging (BCDOI) network, sponsored by the NCIs Networks for Translational Research: Optical Imaging (NTROI). 5 year, $18M program started Sept. 2003 UCI (B. Tromberg, PI), MIT/MGH, Dartmouth, UPENN, SCR, U. Illinois, NIH This talk introduces the BCDOIs plans for developing a MIRC-based infra-structure to support multi-institutional imaging research Our extensions to MIRC, called C-MIRC (C for Collaboration), will be made in a general way to support multi-institutional imaging research projects The spirit of C-MIRC is to provide a Collaborative Lab Notebook to enable the multi-institutional team to function as a seamless organization we invite your suggestions! Slide 3 S I E M E N S C O R P O R A T E R E S E A R C H C-MIRC Hierarchical Data Representation Program Project Experiment Subject Study Series Data The Data can be in many formats and containers, including DICOM/PACS, but also unstructured documents whatever is convenient to the researcher. (e.g., Multimodal Fusion) (e.g., MR/Optical Fusion, or Tomosynthesis/Optical Fusion) (e.g., MR/Optical with UPENN imager using ICG contrast) Research Category Levels Data Levels Slide 4 S I E M E N S C O R P O R A T E R E S E A R C H PACS Files Centralized Management of Metadata, Forms, User Accounts, Distributed Local Storage of Data Forms, Users, Metadata PACS Files PACS Files Lab Data PACS Lab Data Dartmouth UPENN UCI SCR Secure Connection Links to Image/Lab Data Links to Image/Lab Data MIT-MGH Slide 5 S I E M E N S C O R P O R A T E R E S E A R C H C-MIRC Service Overview C-MIRC Data Exchange via XML over the Internet Experiment Submit MIRC Core Services Experiment Collection Tree Storage Tree Query Collaborative Notification Compute Plugins CLN: Collaborative Lab Notebook Meta data CLN Specific Services MIRC Extension Services CLN Integrated Bulletin Board Slide 6 S I E M E N S C O R P O R A T E R E S E A R C H Enter Username and Password to logon to the system. Slide 7 S I E M E N S C O R P O R A T E R E S E A R C H Where Am I Navigation within Hierachy Recent Messages and tasks pending. Slide 8 S I E M E N S C O R P O R A T E R E S E A R C H List of Experiments we can currenty access Slide 9 S I E M E N S C O R P O R A T E R E S E A R C H We can link data to a Study be selecting a PACS. Slide 10 S I E M E N S C O R P O R A T E R E S E A R C H Browse the PACS structure and add pictures. Slide 11 S I E M E N S C O R P O R A T E R E S E A R C H We want to search for some data at the C-MIRC at UPENN. Select UPENN from The listbox in the Program tab Slide 12 S I E M E N S C O R P O R A T E R E S E A R C H We want to search for some data at the C-MIRC at UPENN. Select UPENN from The listbox in the Program tab To see which projects there are within this program click the Project Tab Slide 13 S I E M E N S C O R P O R A T E R E S E A R C H There are currently only two projects at UPENN. We select the DOT/MR Fusion Project... Slide 14 S I E M E N S C O R P O R A T E R E S E A R C H There are currently only two projects at UPENN. We select the DOT/MR Fusion Project...... And hit the search button. Slide 15 S I E M E N S C O R P O R A T E R E S E A R C H As a result we get the records found as a tree. To make the tree simpler, we can change the hierachy level to Experiment. Slide 16 S I E M E N S C O R P O R A T E R E S E A R C H Now the tree starts with the Experiment. By clicking on Listview we get a list of all Experiments (Hierachy Level). Slide 17 S I E M E N S C O R P O R A T E R E S E A R C H This Project contains one Expertiment. By Clicking on the Experiment, we get the Subjects below. Slide 18 S I E M E N S C O R P O R A T E R E S E A R C H This Experiment contains two Subjects. Notice, that the Hierachy chanced to Subject. Slide 19 S I E M E N S C O R P O R A T E R E S E A R C H Next Steps Sept 2004: Project started Currently refining user interface concepts and data architecture with university partners Jan 2005: First MIRC system deployed to get feet wet June 2005; First C-MIRC deployed to UPENN Oct 2005: begin deploy C-MIRC to all consortia members, expand functionality based on feedback during the next year. We welcome your feedback! Slide 20 S I E M E N S C O R P O R A T E R E S E A R C H MIRC Extension Service Tree Query Service: Enables MIRC users to query data stored within NOMIC systems. Tree Submit Service: Enables MIRC users to place MIRC documents within the tree structure of NOMIC. Smart Notification Service : Send Messages in relation to information stored in a NOMIC system. Slide 21 S I E M E N S C O R P O R A T E R E S E A R C H NOMIC Sample Experiment Data Program Project Experiment Subject Study Series Data Breath Caner Vaccines Caner Vaccines Vaccine HER-2 on Residual DNA Andrea, Johnson; 09/10/1978.. Study AttributeData Date7/14/2004; 11:00 Type of DeviceFrequ. Domain Frequency100 400 Sources8 Power (mW)10 Detectors16 Wavelength6... Series AttributeData Scan Time1 sek Detector Separation2, 4, 6 Source Separation4 Hb+2uM HbO2-1 um H2OOK Lipid+ 10 %... Lab AttributeData Solution Time (h)4 Sensor TissueDirect Pressure300 Breast Diameter10 A priori dataMRI BeaconLDL Receptor FluorochomeCy 5,5... Callibration Data Slide 22 S I E M E N S C O R P O R A T E R E S E A R C H NOMIC Functionality Overview Use RSNA MIRC multi-site web technology for sharing, distributing and collecting medical experiment data While NOMIC focuses on the experiment hierarchy model, MIRC focuses on the teaching document model. They have shared data elements. NOMIC will function as a collaboratory lab notebook (CLN) to support experiment submission, query and collection among multiple NOMIC sites NOMIC can exchange experiment records over the internet using MIRC based XML Schema Slide 23 S I E M E N S C O R P O R A T E R E S E A R C H CLN Specific Services Experiment Submit Service: Link data from PACS/FTP/File Servers to RDBMS. Experiment Collection Service: Automatic collecting experitment data from multiple NOMIC sites; The output forms of collected data will be based on format criteria such as Excel and CVS CLN Plugin Service: Interface for advanced lab data online analysis.