Strategy Playbook

VibraCool Drug Free Pain SolutionFDA Cleared to Control PainNovel Intuitive Technology Drug Free Pain Relief

0Everybody hurts. Massaging a muscle improves blood flow, and putting cold on an injury is as old as Ice. At MedTrade, were launching VibraCool, an ergonomically configured high frequency massage unit with two unique ice packs to block pain. Our techonology is FDA cleared to control pain, using a Novel Intuitive Technology we expect to become the new standard for Drug Free Pain Relief.

Product DetailsPain Management $60B2% currently spent on devicesTENS units have equivocal data Our technology effective in over 18 published studies.Both ice and vibration proven to enhance healing and pain reliefFDARegistered 20082014 Novel Product CodeExpanded 510K indications - Relief of muscle & injury pain, myofascial trigger pointsVibraCoolMSRP $59.95Includes 2 AAA batteries, 2 reusable single patient ice wings, Velcro Strap, Vibration UnitVibraCool.com websiteOTC, PT, Ortho, PodiatryCarpal TunnelPlantar FasciitisTennis ElbowPost-op Knee painRunning Injuries

60B market, with chronic pain making up bulk2B spent on devicesExisting TENS unit devices data poor efficacy for chronic pain52.2M adults with diagnosed arthritis pain -> 67M 2030Pain relief options (opioids/narcotics) becoming limitedAthletes using vibration and cold independently for training

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The Birth of a New Technology

AARP 2013, cold and vibration for pain were voted the most liked and loved technology of 20 health tech start ups, even though the device was marketed for needle pain and looked like a bee.

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The Birth of a New Technology

As a physician, our founder knew that pain could be blocked with competing stimuli. Bump an elbow, you rub it. Burn your finger, running cold water stops the pain. By putting cold and vibration between the brain and the pain, our flagship product Buzzy could eliminate sharp pain. Dr. Baxter envisioned a world where shots didnt hurt, empowering kids, and improving compliance. Then, we were invited to the AARP. What did seniors want with a vibrating bee?Lenore told us. The whole AARP told us our produce was the most liked of all 20 new health tech companies. Then we realized, Everybody hurts. If we can stop needle pain, how much easier to stop pain from feet, arms, legs, backs, necks? 3

New OpportunitiesSports vibration now used for training to decrease Delayed Onset Muscle SorenessChronic Pain whole body vibration effectiveAching, Overuse syndromes need anti-inflammatory ice as well as massaging vibration to be effectiveData for plantar fasciitisReduced pain by halfIncreased pain free days 30%

DOMS = delayed onset muscle sorenessHFLA = High frequency low amplitude4

Testimonials

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Product Details

VibraCoolMSRP $59.95 WS $29.95Includes 2 AAA batteries, 2 reusable single patient ice wings, Velcro Strap, Vibration UnitVibraCool.com websiteMMJ Labs EDI compliant system

60B market, with chronic pain making up bulk2B spent on devicesExisting TENS unit devices data poor efficacy for chronic pain52.2M adults with diagnosed arthritis pain -> 67M 2030Pain relief options (opioids/narcotics) becoming limitedAthletes using vibration and cold independently for training

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Testimonials Marathon Runner

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Testimonials Physical Therapy

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Vibration Research Muscle Soreness,Training, Rehab, Pain, HealingA Randomized, Double-Blinded, Placebo-Controlled Clinical Trial Evaluating the Effectiveness of Daily Vibration After Arthroscopic Rotator Cuff Repair. Lam PH, Hansen K, et al. Am J Sports Med 2015 43: 2774. 5 minutes of vibration was applied daily after arthroscopic rotator cuff repair for 6 months. Vibration did provide acute pain relief at 6 weeks after surgery (visual analog scale [VAS] score, 2.24 6 0.29 cm) compared with placebo (VAS score, 3.67 6 0.48 cm) (P\.003). Improvement of stance control and muscle performance induced by focal muscle vibration in young-elderly women: a randomized controlled trial. Filippi GM, Brunetti O, Botti FM. Arch Phys Med Rehabil. 2009 Dec(12):2019-25 Focal vibration of quadriceps muscle enhances leg power and decreases knee joint laxity in female volleyball players. Brunetti O, Botti FM et al. J Sports Med Phys Fitness. 2012 Dec;52(6):596-605. Luo J, McNamara BP, Moran K. A portable vibrator for muscle performance enhancement by means of direct muscle tendon stimulation. Med Eng Phys. 2005;27(6):513-522.Gilsanz V, Wren TA, Sanchez M, Dorey F, Judex S, Rubin C. Low-level, high-frequency mechanical signals enhance musculoskeletal development of young women with low BMD. J Bone Miner Res. 2006;21(9):1464-1474.Gusi N, Raimundo A, Leal A. Low-frequency vibratory exercise reduces the risk of bone fracture more than walking: a randomized controlled trial. BMC Musculoskelet Disord. 2006;7:92.Brunetti O, Filippi GM, Lorenzini M, et al. Improvement of posture stability by vibratory stimulation following anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2006; 43(11):1180-1187.To Compare the Effect of Vibration Therapy and Massage in Prevention of Delayed Onset Muscle Soreness (DOMS). Imtiyaz S, Vegar Z, Shareef MY. J Clin Diagn Res. 2014 Jan;8(1):133-6. Vibration Therapy in Management of Delayed Onset Muscle Soreness (DOMS). Vegar Z. Imtiyaz S. J Clin Diagn Res. 2014 Jun;8(6)LE01-4Effects of vibratory stimulations on maximal voluntary isometric contraction from delayed onset muscle soreness. Koh HW, Cho SH et al. J Phys Ther Sci. 2013 Sep;25(9):1093-5. Vibration Therapy Reduces Plasma IL6 and Muscle Soreness After Downhill Running. Broadbent S, Rousseau J, J. Throp RM, Choate SL, Jackson FS, Rowlands DS. Br J Sports Med. 2010;44:888894. Kakigi R, Shibasaki H. Mechanisms of pain relief by vibration and movement. J Neurol Neurosurg Psychiatry. 1992;55:282286. doi: 10.1136/jnnp.55.4.282.Lundeberg T, Nordemar R, Ottoson D. Pain alleviation by vibration stimulation. Pain. 1984. pp. 2544.