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Model 100 Series User’s Manual Publicaon 5600-001 REV-G

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Model 100 SeriesUser’s Manual

Publication 5600-001 REV-G

1 Publication 5600-001 REV-G

Table of Contents

SUBJECT PAGE #

General Safety Summary 2

Technical Specifications 4

Features 6

Keypad Functions 7

Operating InstructionsPower Switch 8

Main Menu 8

Syringe Diameter Entry 8

Volume Entry 9

Flowrate Entry 9

Start the Pump 10

Power Failure Mode 10

Change or Review Volume Setting While Running 11

Change or Review Rate Setting While Running 11

Fast Forward 11

Loading the Syringe 12

Manual Stall Setting and Microliter Syringes 14

NV Ram Failure 14

Fuses 14

Voltage Selector (CE version only) 15

Maintenance 15

Standard Table of Syringe Diameters 16

Japanese Table of Syringe Diameters 17

Standard Minimum and Maximum Flow Rates 18

Model Numbers 19

Limited Warranty 20

2 Publication 5600-001 REV-G

Please read the following safety precautions to ensure proper use of your syringe pump. To avoid potential hazards and product damage, use this product only as instructed in this manual. If the equipment is used in a manner not specified by the manufacturer, the protection provided by the equipment may be impaired.

To Prevent Hazard or Injury:Avoid Exposed Circuitry

Do not touch any electronic circuitry inside of the product.

Avoid Pinch HazardA pinch hazard may exist between the Pusher Block and the End Blocks. Avoid placing fingers between these points while the pump is running.

Do Not Operate with Suspected Failures

If damage is suspected on or to the product do not operate the product. Contact qualified service personnel to perform inspection.

Ground the Product

This product is grounded through the grounding conductor of the power cord. To avoid electric shock, the grounding conductor must be connected to earth ground. Before making any connections to the input or output terminals of the product, ensure that the product is properly grounded.

Make Proper Connections

Make sure all connections are made properly and securely.

General Safety Summary

3 Publication 5600-001 REV-G

Observe all Terminal Ratings

Review the operating manual to learn the ratings on all connections.

Orient Equipment Properly

Do not position the equipment such that it is difficult to reach the disconnecting device.

Place Product in Proper Environment

Review the operating manual for guidelines for proper operating environments.

Use Proper Fuse

Use only specified fuses with product.

Use Proper Line Cord

Use only the line cord shipped with the product and make sure the line cord is certified for the country of use.

Observe all Warning Labels on Product

Read all labels on product to ensure proper usage.

CAUTIONRefer to Manual

CAUTION: This pump is not registered with the FDA and is not for clinical use on human or veterinary patients. It is intended for research use only.

Protective Ground Terminal

General Safety Summary

4 Publication 5600-001 REV-G

Technical Specifications

100 Series, Including KDS100, 101 and 120Syringe Size 10 microliter - 60 milliliter

Electrical Rating Model 115V ~, 0.1A

CE model 230V ~, 0.06A

Fuse 5 x 20 mm, 250V ~, slow blow, 0.1A

Voltage Operating Range

Model 100-120V ~, 50/60Hz

CE model 200-240V ~, 50/60Hz

Drive Mechanism Microprocessor controlled stepper gearmotor (½ microstepping), driving a leadscrew through a belt and pulley drive mechanism

Pusher Advance per Half Step

~ 0.529 micron or 2.083 x 10-5 in (KDS100)

~ 0.088 micron (KDS101)

Linear Travel

KDS100, KDS120 Min 0.00635 cm/hr; Max 76.18 cm/hr

KDS101 Min 0.00106 cm/hr; Max 12.2 cm/hr

Step Rate

Min One ½ step in 30 seconds - may vary depending on syringe size

Max 400 ½ steps / second

Speed Range 12000:1

Flowrate Range 0.1 µl/hr (10 µl syringe) - 426 ml/hr (60 ml syringe)

5 Publication 5600-001 REV-G

Technical Specifications

Linear Force 20 Ib min (9 Kg)

Dimensions, W x D x H 9 x 6 x 5 in (23 x 15.25 x 13 cm)

Weight 4.5 Ib (2 Kg)

Atmospheric Specs

Temperature 4˚ C - 40˚ C (40˚ F - 104˚ F)

Humidity 20% - 80% RH, non-condensing

Mode of Operation Continuous

Classification Class I

Pollution Degree 2

Installation Category II

Output N/A

Physiological Effects N/A

Cooling Conditions No special considerations

Mechanical Stability No special considerations

Protective Packaging No special considerations

Earth Terminals No External connections required

Removable Protective Means N/A

Supplier Name KD Scientific Inc.

Address 84 October Hill Road, Holliston, MA 01746

6 Publication 5600-001 REV-G

Features

The Model 100 series are simple, accurate and cost effective syringe pumps designed to hold glass or plastic syringes, of any make, from 10 microliter - 60 milliliter for the KDS100; 10 µl - 15 ml for the KDS120; and 10 µl - 10 ml for the KDS101.

The models KDS100 and KDS101 are infusion only pumps. The flow rates of the KDS101 are six times slower than that of the KDS100 and the units of flow rate are suitably adjusted. The KDS120 is a push-pull simultaneous infusion/withdrawal pump.

Setup and pump operation for all of the 100 series pumps are similar and extremely simple. A menu, displayed on an alphanumeric LCD “prompts” the operator to make the necessary selections using the keypad for choice of features and numerical entries.

The internal diameter of the syringe is used by the control program to calibrate the pump and deliver the volume and flowrate selected. For simplicity the syringe diameter is also used to set automatically the volume and flowrate units.

The syringe diameter can be entered directly or the syringe can be identified from a table of syringes held in memory. When the syringe is selected from the table the diameter is entered automatically.

Two dispense modes are available:

a. Dispense volume mode, in which the pump keeps track of the volume dispensed and automatically stops the pump when a set target volume is reached.

b. Run mode, where the pump runs at the set flowrate until manually stopped.

In the event of a power interruption during operation, the pump can be programmed to either resume operation or remain stopped when power is returned.

For convenience, all pump settings are stored in non-volatile memory to minimize the number of setting changes required.

7 Publication 5600-001 REV-G

Keypad Functions

This key has two functions:

a. Moves the display to the left.

b. Causes the numerical entry to decrease. To change the displayed number by a single unit press and release the key quickly. If the key is pressed longer the number changes with increasing speed.

This key has two functions.

a. Moves the display to the right.

b. Causes the numerical entry to increase. To change the displayed number by a single unit press and release the key quickly. If the key is pressed longer the number changes with increasing speed.

select This key has three functions:

a. Return to main menu when pressed repeatedly.

b. Selects the pulsing or “highlighted” feature of the main menu display.

c. Enter numerical values.

run/stop

a. Turns the motor on and off.

b. Acts as a “pause” during a dispense.

DISPLAYAfter the pump is programmed an arrow on the right side of the display indicates the direction of operation. This arrow pulses when the pump is running.

8 Publication 5600-001 REV-G

Operating Instructions

POWER SWITCHThe power switch is located at the right, rear corner of the pump. When the power is turned on the LCD will display the Volume or Rate setting. Press the select key to return to the main menu.

MAIN MENUPressing select repeatedly will always return the display to the main menu. The main menu consists of five variables, three of which are displayed at all times. The center variable pulses to indicate that this option can be reviewed or changed. The menu acts as a continuous loop and the arrow keys, ↙ ↗ are used to move around the loop. The variable to be changed can be selected with the select key.

←→ dia ←→ table ←→ rate ←→ vol ←→ pwr up ←→direct entry syr dia (mm)

syr dia mfr, size

flowrate µl or ml/h

dispense vol µl or ml

run/stop

SYRINGE DIAMETER ENTRY Syringe diameter must be entered for automatic internal calibration. Once the diameter is entered, it is retained in non-volatile memory and need not be entered again unless the syringe being used is changed. When a syringe diameter is changed the Volume and Rate settings are set to zero.

There are two methods of diameter entry.

a. Internal LibrarySelect TABLE from the main line menu. The table of syringes is organized by manufacturer, then by glass or plastic, and then by size. Use the arrow keys to scroll through the table and the select key to enter the correct setting.

First, scroll through the manufacturers and select the manufacturer of the syringe used. The menu will next display either syringe type or syringe size.

Again, use the arrow keys to move through the table until the correct size is displayed. Press the select key when the correct syringe size is displayed. This automatically enters the internal syringe diameter.

See Table of Syringe Diameters for the syringe library.

b. Direct EntryFrom the main menu select DIA. The display will read “xx.xx mm”. Use the arrow keys to display the measured internal diameter of the syringe in millimeters and enter with the select key.

Changing the diameter clears the Volume and Rate settings, and the display will now prompt for the new Volume setting.

9 Publication 5600-001 REV-G

Operating Instructions

VOLUME ENTRY The volume setting mode is selected from the main menu or is displayed automatically after changing the diameter.

Display reads: xx.xx µl (Units displayed in µl or ml depend on syringe diameter entered)

1. Use the arrow keys to enter the dispense volume required.

2. When the correct dispense volume is displayed save this number with the select key.

Note: If no target dispense volume is required, enter volume = 0.0. The pump will run at the set flowrate until stopped manually or a stall occurs.

3. After setting a volume the menu prompts for the flowrate setting. When the pump runs, the actual dispensed volume will be displayed and will increment until the set volume is reached, at which time the pump will stop automatically.

FLOWRATE ENTRYRATE can be selected from the main menu or will be displayed automatically after the volume setting.

The display reads: Rate: X.X µl/h or X.X ml/h

Rate units are µl/h or ml/h, microliter or milliliter/hour and are selected automatically according to the syringe diameter.

1. Use the arrow keys to display the flowrate required.

2. Enter the rate with the select key.

3. If the rate entered is out of range, a message is displayed:

“Max Rate XX ml/h”

To continue, enter a lower rate or select a larger syringe.

Note: a. If a dispense volume was set then the display will now change to “Volume : 0.0” ,that is, in automatic dispense mode.

When the pump runs, the actual dispensed volume will be displayed and will increment until the set volume is reached, at which time the pump will stop automatically.b. If no dispense volume is set, the LCD displays the set flowrate and, when running, the directional indicator arrow will pulse.

10 Publication 5600-001 REV-G

Operating Instructions

START THE PUMPa. Press the run/stop key to start the pump. A second press will stop the pump.

b. If the pump is stopped during a dispense, the volume accumulator is not cleared - the dispense is paused. Restarting the pump with a second press of the run/stop key continues the dispense to the target volume.

POWER FAILURE MODEIf there is a temporary power interruption, when no dispense volume is selected, the Power Up run/stop option allows the pump to either resume the dispense when the power returns, or remain stopped but display a message warning of the power failure.

1. Move the main menu to the right and select PWR UP.

2. The display will read Power Up Run (or STOP). Use the arrow keys to change display and select the required option.

Run After power is returned, the pump resumes normal operation. The display flashes PowerFailed to acknowledge a power interruption. Press Select to display the Rate.

STOP Pump does not run when power returns. The LCD displays the rate setting.

If a dispense volume is entered the power interruption stops the pump, clears the volume accumulator and returns the volume to the setpoint. Only if the power failure setting is “run” will the power failure warning be displayed.

11 Publication 5600-001 REV-G

Operating Instructions

CHANGE OR REVIEW VOLUME SETTING WHILE RUNNINGWhile the pump is running it is possible to look at the volume and flowrate settings without interrupting the operation of the pump. If required, the volume and flowrate settings can be changed while the pump continues to run. When the changes are entered the pump immediately changes to the new settings.

1. While operating, press select to return to the main menu.

2. Select Volume to display the set dispense volume. If no change is required press select.

3. For a volume change use the arrow keys and enter with the select key.

4. The display moves to RATE, permitting a change if required. Press select if no change is required, or use the arrow keys to change the setting. The select key immediately changes to the new flowrate and the volume display continues to increment, uninterrupted to the new dispense setting.

Note: If the VOLUME is changed to a setting smaller than the volume already accumulated then the pump stops when the new, smaller dispense volume is selected.

CHANGE OR REVIEW RATE SETTING WHILE RUNNING

1. Press select to change the volume accumulator display to the main menu.

2. Select RATE.

3. Make rate changes, if required, and press select.

The pump immediately changes to the new flow rate and displays the continuing volume accumulation uninterrupted by the change in flowrate.

FAST FORWARDPress the run and the → keys simultaneously to actuate the fast forward mode. The pump travels at its maximum rate while both keys are pressed simultaneously.

12 Publication 5600-001 REV-G

Loading the Syringe

KDS100 AND KDS101

To facilitate loading, the pusher block (1) can be released from the leadscrew and manually moved along the guide rods to accommodate the syringe.

Press the bronze release button (2) on the side of the black pusher block (1) to release the block from the leadscrew.

Raise the spring loaded retaining clamp knob (3) and rotate away from the syringe barrel.

Place the syringe barrel in the V of the syringe holder, making sure that the flange of the syringe barrel is pressed against the side of the syringe holder.

Rotate and release the syringe clamp to hold the syringe in place.

Press in release button (2) and move the pusher block back along the guide rods to make contact with the syringe plunger.

GLASS SYRINGESWith some glass syringes the corners of the flange of the syringe barrel are rounded and can cause a tendency for the syringe barrel to ride up out of the syringe holder.

To give a more secure, flatter surface to clamp against, an O-ring or metal collar can be placed over the barrel and pressed against the flange.

(1) Pusher Block

Syringe Plunger (3) Syringe Clamp Knob

Syringe Holder(2) Release Button

13 Publication 5600-001 REV-G

Loading the Syringe

KDS120 PUSH-PULL PUMP

Travel Direction

Withdraw Clamp Syringe Clamp

Syringe RestRelease Button

Withdraw Bracket Clamp

To facilitate loading, the pusher block can be released from the leadscrew by pressing the bronze release button and can be manually moved along the guide rods to accommodate the syringes.

First place the withdraw syringe in the withdraw syringe holder, using the spring loaded retaining clamp to retain the syringe barrel in the V of the syringe holder.

Make sure the barrel flange is held firmly by the withdraw clamp and that the adjusting screws on the withdraw clamp are firmly tightened.

While keeping the button pressed firmly “in” slide the block along the guide rods so that the syringe plunger flange can be retained by the clamp on the pusher block. Tighten the locking screws on the adjusted syringe clamp.

Loosen the locking screw on the Adjustable syringe rest and position the rest so that the plunger of the loaded syringe is pressed firmly against the pusher block and the syringe barrel flange is pressed up to the syringe rest.

The barrel of the loaded, infusion syringe should be clamped in the V of the syringe holder with the spring loaded clamp.

Tighten the screw on the syringe rest to lock the rest in place on the guide rod.

14 Publication 5600-001 REV-G

Manual Stall Setting and Microliter Syringes

NV Ram Failure

Fuses

A movable collar, located on the rear guide rod, can be set to restrict travel of the pusher block. The block moves until stalling against the collar. Stalling does no permanent damage but may result in increased wear on the drive mechanism and should not be used routinely but only as a “fail safe” device.

Microliter syringes with fine wire plungers can be damaged if the plunger is forced into the end of the syringe barrel; the collar can be adjusted to prevent this occurrence.

If the settings in the non-volatile memory become corrupted the display will read “NV Ram Failure” and the pump will not operate.

To recover from this condition, the pump must be powered down and then turned on again. The pump will be re-initialized to the default settings and can now be programmed as normal.

A second method of clearing the “NV Ram Failure” is to press select and then enter a changed rate setting.

The fuses are located in the power entry module on the rear panel. The linecord must be first removed to gain access to the fuse holder.

Fuses 5x20mm, 250V~ slow blow, 0.1A

15 Publication 5600-001 REV-G

If it is necessary to change the input voltage selection, disconnect the line cord from the entry module on the rear panel. Use a flat bladed screwdriver to open the Fuse Holder access door. Remove the Fuse Holder, flip over, and reinstall. Close the access door. The new input voltage selection should be visible through the door window. Install a proper line cord certified for the country of use.

Voltage Selector

Maintenance

Maintenance is required only for the moving mechanical parts, which should be kept clean and lubricated. Occasionally, a small amount of light machine oil should be applied to the guide rods and a small amount of grease or oil to the leadscrew.

Solvents of any type should never be used to clean the pump. A mild detergent solution may be used to clean the keypad.

Fuse Holder

16 Publication 5600-001 REV-G

Becton Dickson Glass - all types0.5 cc 4.64 mm1 4.642.5 8.665 11.8610 14.3420 19.1330 22.7060 28.60

Standard Table of Syringe Diameters

“Air-Tite“ All Plastic

1 cc 4.70 mm2.5 9.705.0 12.4810 15.8920 20.0030 22.5050 28.90

Becton Dickinson Interim, WW design, Plastipak1 cc 4.70 mm3 8.595 11.9910 14.4820 19.0530 21.5960 26.60

Hamilton 1000-Series Gastight10 µl 0.46 mm25 0.7350 1.03100 1.46250 2.30500 3.261 ml 4.61 mm2.5 7.285 10.3010 14.5725 23.0350 32.57

Cadence Science, Inc.Formerly Popper & Sons, Inc. Perfektum glass0.25 3.45 mm0.5 3.451 4.502 8.923 8.995 11.7010 14.7020 19.5830 22.7050 29.00

Ranfac2 cc 9.12 mm5 12.3410 14.5520 19.8630 23.2050 27.60

Scientific Glass Engineering SGE25 µl 0.73 mm50 1.03100 1.46250 2.30500 3.261 ml 4.61 mm2.5 7.285 10.3010 14.57

Sherwood - Monojet Plastic1 cc 4.674 mm3 8.8656 12.60012 15.62120 20.14235 23.57160 26.568

Terumo1 cc 4.73 mm3 9.005 13.0410 15.7920 20.1830 23.3660 29.45

Unimetrics Series 900010 µl 0.46 mm25 0.7350 1.03100 1.46250 2.30500 3.261000 4.61

17 Publication 5600-001 REV-G

Becton Dickson Glass - all types0.5 cc 4.64 mm1 4.642.5 8.665 11.8610 14.3420 19.1330 22.7060 28.60

Japanese Table of Syringe Diameters (available in Japanese Models)

“Air-Tite” All Plastic

1 cc 4.70 mm2.5 9.705.0 12.4810 15.8920 20.0030 22.5050 28.90

Becton Dickinson Interim, WW design, Plastipak1 cc 4.70 mm3 8.595 11.9910 14.4820 19.0530 21.5960 26.60

Hamilton 1000-Series Gastight10 µl 0.46 mm25 0.7350 1.03100 1.46250 2.30500 3.261 ml 4.61 mm2.5 7.285 10.3010 14.5725 23.0350 32.57

Terumo1 ml 4.73 mm3 9.005 13.0410 15.7920 20.1830 23.3660 29.45

Nipro1 ml short

6.61 mm

1 ml long

4.75

3 9.535 12.9610 15.7820 20.0730 23.1750 29.13

Hoshi1 ml sm 4.80 mm1 ml lg 6.702 ml sm 6.702 ml lg 9.203 10.305 12.2010 15.0020 19.0030 22.5050 25.50100 34.00

Natsume0.25 ml 2.60 mm0.50 3.201 4.302 6.303 7.305 9.50

Top1 ml 4.70 mm2 6.403 9.306 13.1012 15.4025 21.0030 23.0050 29.00

JMC Air-Tite pls1 ml 4.66 mm2 6.902.5 9.105 12.6210 14.3420 19.6830 22.4450 28.80100 36.68

Terumo Japan

1 ml sm 4.73 mm

1 ml lg 6.50

3 8.95

5 13.00

10 15.80

20 20.15

30 23.10

50 29.10

18 Publication 5600-001 REV-G

Standard Minimum & Maximum Flowrates

MODEL KDS 100Syringe size Minimum Maximum

10 µl 0.1 µl/h 126 µl/h

25 µl 0.1 µl/h 318 µl/h

50 µl 0.2 µl/h 625 µl/h

100 µl 1.0 µl/h 1274 µl/h

250 µl 2.0 µl/h 3164 µl/h

500 µl 3.0 µl/h 6359 µl/h

1 ml 0.01 ml/h 13.2 ml/h

2.5 ml 0.02 ml/h 31.7 ml/h

3 ml 0.02 ml/h 44.9 ml/h

5 ml 0.03 ml/h 87.0 ml/h

10 ml 0.1 ml/h 125 ml/h

20 ml 0.1 ml/h 219 ml/h

30 ml 0.1 ml/h 282 ml/h

60 ml 0.2 ml/h 426 ml/h

MODEL KDS 120Syringe size Minimum Maximum

10 µl 0.1 µl/h 126 µl/h

25 µl 0.1 µl/h 318 µl/h

50 µl 0.2 µl/h 625 µl/h

100 µl 1.0 µl/h 1274 µl/h

250 µl 2.0 µl/h 3164 µl/h

500 µl 3.0 µl/h 6359 µl/h

1 ml 0.01 ml/h 13.2 ml/h

2.5 ml 0.02 ml/h 31.7 ml/h

3 ml 0.02 ml/h 44.9 ml/h

5 ml 0.03 ml/h 87.0 ml/h

10 ml 0.1 ml/h 125 ml/h

MODEL KDS 101Syringe size Minimum Maximum

10 µl 0.001 µl/m 0.382 µl/m

25 µl 0.001 µl/m 1.010 µl/m

50 µl 0.001 µl/m 1.762 µl/m

100 µl 0.001 µl/m 3.542 µl/m

250 µl 0.01 µl/m 8.78 µl/m

500 µl 0.01 µl/m 17.65 µl/m

1 ml 0.1 µl/m 35.2 µl/m

2.5 ml 0.1 µl/m 88.0 µl/m

3 ml 0.1 µl/m 122.5 µl/m

5 ml 0.1 µl/m 176.2 µl/m

10 ml 0.001 ml/m 0.351 ml/m

19 Publication 5600-001 REV-G

Model Numbers

Legacy Model KDS 100 KDS 101 KDS 120Order Code 110 VAC 78-0100 78-0101 78-0120

Order Code 220 VAC with CE Mark 78-9100 78-9101 78-9120

Notes:KDS 100 Y suffix: Integrated footswitch capability.KDS 100 ZZ suffix: LED option with end of run alarm.All part numbers subject to change; please contact KD Scientific for additional information.

20 Publication 5600-001 REV-G

Limited Warranty

KD Scientific Inc. warrants to the first consumer purchaser, for a period of one year from the date of purchase that this unit, when shipped in its original container, will be free from defective workmanship and materials and agree that it will, at its option, either repair or replace the defective unit.

This warranty does not extend to misuse, neglect or abuse, normal wear and tear, accident, modification or unauthorized repair.

KD Scientific will not be liable or in any way responsible for any incidental or consequential economic or property damage. Some States do not allow the exclusion of incidental or consequential damages, so the above exclusion may not apply to you.

There are no implied warranties of merchantability, or fitness for a particular use, or of any other nature. Some states do not allow this limitation on implied warranty, so the above limitation may not apply to you.

If a defect arises within the warranty period contact KD Scientific Inc. (see address below).

The customer is responsible for shipping charges and must first obtain a Return Material Authorization number (RMA) before the unit will be accepted. If a replacement unit is issued it is covered only for the remainder of the original warranty period dating from the purchase of the original device.

This warranty gives you specific legal rights. You may also have other rights which vary from state to state.

Note: This pump is not registered with the FDA and is not for clinical use on patients.

Syringe pumps are manufactured by:

KD Scientific Inc.

84 October Hill Road

Holliston, MA 01746

phone: 508.429.6809 | fax: 508.893.0160

email: [email protected]

www.kdscientific.com

Declaration of Conformity

Manufacturer: KD Scientific Inc. 84 October Hill Rd. Holliston, MA 01746-1388 U.S.A. Phone: (508) 429-6809

We herewith declare that the following product:

Product Name: Model 100 Series Syringe Pump

Model Numbers: KD100, KD101, KD120

To which this declaration relates, is in conformity with the applicable EC Directives, harmonized standards, and other normative requirements:

Application of Council Directive(s): 2006/95/EC, 89/336/EEC

Standard(s) to which Conformity is Declared:

Safety: IEC 61010-1:2012 Ed. 3

Emissions/Immunity: EN 61326:1997 w/ A1:1998 and A2: 2001

EN 61000-4-2:1995

EN 61000-4-3:1995

EN 61000-4-4:1995

EN 61000-4-5:1995

EN 61000-4-6:1996

EN 61000-4-11:1994

EN 61000-3-2:2001 w/ A.14

EN 61000-3-3:1995

EMC and Safety compliance were evaluated by Intertek/ETL Semko

Reference test report file numbers: 3086793 .Box.001 & .Box.002 and 101450664 .Box.003

Signature: Date: 7/30/14

Mark Davis, Director, Global MPE