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UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected] Modeling to mitigate COVID-19 Lauren Ancel Meyers May 14, 2020

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Page 1: Modeling to mitigate COVID-19 - TAMEST

UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected]

Modeling to mitigate COVID-19

Lauren Ancel MeyersMay 14, 2020

Page 2: Modeling to mitigate COVID-19 - TAMEST

UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected]

Decision support

CDC FluCode - Pandemic Model (2020)

15% 35%

High risk

Pandemic Exercise Tool (2013)

Page 3: Modeling to mitigate COVID-19 - TAMEST

UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected]

Public outreach

Page 4: Modeling to mitigate COVID-19 - TAMEST

UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected]

1. Spreads far and fast

Dec. 1

Dec. 8

Jan.

10

Jan.

22100

105

Cum

mul

ativ

e ca

ses

Cum

ulat

ive

case

s

Du et al. (2020) Risk for Transportation of 2019 Novel Coronavirus Disease from Wuhan to Other Cities in China. Emerging Infectious Diseases

425 cases

reported

12,400 cases

estimated

Page 5: Modeling to mitigate COVID-19 - TAMEST

UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected]

2. Forecasting deaths

bars grocery

parksmedical

schoolsrestaurants

at home

Page 6: Modeling to mitigate COVID-19 - TAMEST

UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected]

Ensemble forecasting

Page 7: Modeling to mitigate COVID-19 - TAMEST

UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected]

Stay

Hom

e W

ork

Safe

Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep

7000

6000

5000

4000

3000

2000

1000

0

Hos

pita

lizat

ions

/ De

aths

far more than 3000 deaths

3. What might happen?

hospitalizations

capacity

Schools closed Schools open

deaths

If policies are relaxed and transmission rebounds to half of baseline …

Page 8: Modeling to mitigate COVID-19 - TAMEST

UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected]

Stay

Hom

e W

ork

Safe

Lock

dow

n

Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Sep

7000

6000

5000

4000

3000

2000

1000

0

Hos

pita

lizat

ions

/ De

aths

~3000 deaths

Data-driven trigger

hospitalizations

capacity

What is the shortest lockdown required to prevent an overwhelming surge?

135 days of lockdown

Schools closed Schools open

Page 9: Modeling to mitigate COVID-19 - TAMEST

UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected]

Track and trigger

Hospital admissions

R0

Deaths

R0 > 4

R0 < 0.8 R0 ~ 0.95

Page 10: Modeling to mitigate COVID-19 - TAMEST

UT COVID-19 Modeling Consortium https://covid-19.tacc.utexas.edu/ [email protected]

Funding and teamSimon Cauchemez, Institute Pasteur

Ben Cowling, U Hong KongMaytal Dahan, TACC

Oscar Dowson, Northwestern UniversityZhanwei Du, UT

Daniel Duque Villarreal, NorthwesternSpencer Fox, UT

Kelly Gaither, TACCAlison Galvani, Yale

Neo Huang, Precima, LoyaltyOneEmily Javan, UT

Clay Johnston, Dell MedMichael Lachmann, Santa Fe Institute

David Morton, NorthwesternCiara Nugent, UTRemy Pasco, UT

Michaela Petty, UTKelly Pierce, TACC

Michael Pignone, Dell MedJames Scott, UTMauricio Tec, UT

Suzanna Wang, UTSpencer Woody, UT

US Centers for Disease Control and PreventionNational Institutes of Health

National Science FoundationTexas Advanced Computing Center