module specification - university of leicester · 2015. 8. 3. · module specification no....

Module Specification

No. Assessment Description Weight % Exam Hours Ass't Group Alt Reass't

001 Practical Reports 15002 Essay 15003 Examination (Final) 70 1

Period: Semester 1Occurence: ACoordinator: Tom MathesonMark Scheme: UG Pass for Credit



Period: Semester 1Occurence: ECoordinator: Tom MathesonMark Scheme: UG Pass for Credit


005 Practical Reports 20006 Essay 10008 Open Book Examination (Final) 70 1

Period: Semester 1Occurence: E2Coordinator: Tom MathesonMark Scheme: UG Pass for Credit

Academic Year: 2013/4Module Level: Year 1Scheme: UGDepartment: Biological SciencesCredits: 10

Intended Learning OutcomesAt the completion of the module students will be expected to be able to describe the similarities and differences betweenplants and animals. Know the basic structure and function of cell organelles. Describe the basic principles of plant and animaldevelopment. Explain the role of plant hormones and light as environmental factors regulating plant development. Describethe basic mechanism by which foreign genes can be introduced into plants. Demonstrate ability to use and calibratedissecting and compound microscopes, make observations of and describe different cell types, and to use sterile techniquesin plant tissue culture and be familiar with simple assay methods using spectrophotometry and fluorimetry. Students will alsohave improved their skills in data analysis, presentation, essay writing, team work and communication.

Teaching and Learning MethodsLectures, Tutorials, Laboratory practical classes, Demonstrations, Private study

Lectures 15Seminars

Practical Classes & Workshops 12Tutorials 3

FieldworkProject Supervision

Guided Independent Study 45Demonstration

Supervised time in studio/workshopWork Based Learning

PlacementYear Abroad

Total Module Hours 75

Student Workload (hours)

BS1003 Cell and Developmental Biology

Last Published: 3 August 2015


Assessment MethodsEssays, Written reports, Formative tutorial presentations. Short answer examination.

ERASMUS AND STUDY ABROAD STUDENTSErasmus and year-long Study Abroad students are expected to take assessment pattern E1, which includes the exam, unlesstheir home University notifies us in writing that they are unable to attend during the exam period. In this case the students willthen take assessment pattern E2 (see below).

Study Abroad students attending for one semester only will be assumed to take assessment pattern E2 along with studentswho qualify by the above criteria. All coursework assessments will be the same as Assessment Pattern E1 but an additionalassessment will be set in lieu of the exam. The assessments will be returned as a single coursework mark.

Pre-Requisites

Co-Requisites

Excluded Combinations-

BS1003 Cell and Developmental Biology





Period: Semester 2Occurence: ACoordinator: Ezio RosatoMark Scheme: UG Pass for Credit



Period: Semester 2Occurence: ECoordinator: Ezio RosatoMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module, typical students should be able to... -Describe the effects of mutations and explain howthey arise. -Explain how chromosomes are inherited through mitosis and meiosis and how genetic variation isgenerated. -Carry out elementary genetic analysis and construct a simple linkage map. -Describe the naturalmechanisms of gene transmission in bacteria and how they can be used for gene mapping. -Describe the basicprinciples of gene cloning and the construction of gene libraries in bacteria. -Discuss the basic principles ofgenome sequencing and use of the polymerase chain reaction to amplify and recover specific segments of DNA. -Construct simple restriction enzyme maps of DNA molecules. -Demonstrate a basic understanding of mechanismsof gene regulation in prokaryotes. -Discuss fundamental ideas about control of gene expression in eukaryotes,particularly during development of multicellular organisms. -Work in groups, researching a problem.

Teaching and Learning MethodsLectures, Tutorials, Laboratory practical classes, Problem sets, Help clinics, Self-directed learning

Lectures 15Seminars








BS1005 Genes



Assessment MethodsShort answer examination, essay, laboratory reports.

ERASMUS AND STUDY ABROAD STUDENTSErasmus and year-long Study Abroad students are expected to take assessment pattern E1, which includes the exam, unlesstheir home University notifies us in writing that they are unable to attend during the exam period. In this case the students willthen take assessment pattern E2 (see below).Study Abroad students attending for one semester only will be assumed to take assessment pattern E2 along with studentswho qualify by the above criteria. All coursework assessments will be the same as Assessment Pattern E1 but an additionalassessment will be set in lieu of the exam. The assessments will be returned as a single coursework mark.

Pre-Requisites

Co-Requisites


BS1005 Genes




001 Tutorials 5002 Practicals 25003 Examination (Final) 70 1

Period: Semester 2Occurence: ACoordinator: Blair GrubbMark Scheme: UG Pass for Credit


001 Tutorials 5002 Practicals 25003 Examination (Final) 70 1

Period: Semester 2Occurence: ECoordinator: Blair GrubbMark Scheme: UG Pass for Credit


Intended Learning OutcomesBy the end of the module students should be able to: Describe the processes underpinning permeation across animal membranes, and the roles of channels, carriers and pumps. Describe in outline the origin of the resting potential and the nature of the action potential, including in this an appreciation ofhow ion channels contribute to these two potentials. Describe the meaning of the term 'neurotransmitter' and be able to describe in outline the nature of synaptic transmission atthe neuromuscular junction and in the autonomic nervous system. Describe in outline the nature of excitation-contraction coupling in skeletal, cardiac, and smooth muscle. Describe the control of posture, including reference to the motor unit, the muscle spindle and spinal reflexes. Describe the forces and processes involved in the respiratory apparatus and in gas exchanges in the lungs and tissues Describe the function of the gastrointestinal system and the kidneys in terms of membrane transport and other physicalprocesses under nerve and hormonal control. Describe the nature of molecular receptors, what is meant by an agonist and an antagonist, and how the sympathetic andparasympathetic nervous systems are organised.

Teaching and Learning MethodsLectures, tutorials, practical classes.

Lectures 15Seminars








BS1006 An Introduction to Physiology



Assessment MethodsWritten examination, tutorial attendance/participation and practical assessment


Pre-Requisites

Co-Requisites


BS1006 An Introduction to Physiology




001 Practical Reports 22002 Essay/Debate 8003 Examination (Final) 70 1

Period: Semester 1Occurence: ECoordinator: Sinead DreaMark Scheme: UG Pass for Credit



Period: Semester 2Occurence: ACoordinator: Sinead DreaMark Scheme: UG Pass for Credit



Period: Semester 2Occurence: ECoordinator: Sinead DreaMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module, students should be able to explain the role of natural and sexual selection and other forces in evolution, the evolution of life-history strategies; the scope of population ecology, the ways in which organisms of different species interact, what factors influence global patterns of diversity, and the molecular evolution of genes and genomes.

Teaching and Learning MethodsLectures, Laboratory practical classes, Private study, debate.

Lectures 15Seminars 2

Practical Classes & Workshops 15Tutorials







BS1008 Environmental and Evolutionary Biology



Assessment MethodsWritten reports, Short answer examination


Pre-Requisites

Co-Requisites


BS1008 Environmental and Evolutionary Biology




001 Lab notebook with short essays 30002 Examination (Final) 70 1

Period: Semester 2Occurence: ACoordinator: Shaun HeaphyMark Scheme: UG Pass for Credit


001 Lab notebook with short essays 30002 Examination (Final) 70 1

Period: Semester 2Occurence: ECoordinator: Shaun HeaphyMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module, typical students should be able to: Describe the conceptual advances that have lead to thedevelopment of Microbiology as a discipline. Describe the techniques used to study microorganisms. Describe the diversityof types and structural features of microorganisms, including examples of bacteria, viruses, viroids, virusoids and prions.Describe the diversity of virus genomes and replication strategies. Understand what is meant by bacterial genomics,transduction, transformation and transfection. Understand the principles of modern microbial systematics. Describe some ofthe ways that bacteria and viruses cause disease. Describe the uses of microorganisms in the biotechnology industry,including the application of genetic engineering techniques. Understand the principles of energy generation from chemicalbond energy and light energy. Identify the roles of microorganisms in the cycling of carbon, nitrogen and sulphur, includinginvolvement in geomicrobiological processes such as sulphur deposition and biohydrometallurgy. Describe sewage treatmentsystems as microbial environments. Understand the processes whereby safe drinking water is produced and monitored.Execute the practical skills necessary for the safe handling of microorganisms gained during laboratory studies relevant to thecontents of the module.

Teaching and Learning MethodsLectures, Tutorials, Seminars, Directed reading, Problem solving classes, Laboratory practical classes, Computer-aidedlearning.









BS1009 Microbiology



Assessment MethodsEssays, Short-answer examinations, Laboratory reports.


Pre-Requisites

Co-Requisites


BS1009 Microbiology




001 Coursework (Final) 100

Period: Semester 1Occurence: ACoordinator: Alan CannMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn completion of this module, students are expected to be able to:

* Apply a methodical approach to the solution of numerical problems in the context of biological sciences. * Demonstrate the capacity to apply mathematical, statistical and data handling techniques appropriate to the BiologicalSciences degrees. * Demonstrate the capacity to access scientific literature via online bibliographic databases. * Demonstrate the acquisition of skills and attributes necessary for lifelong learning, including the use of C&IT, the capacityto access a variety of resource materials and effective time management.

Teaching and Learning Methods1 lecture, 19 computer practical classes, directed reading.

Assessment MethodsComputer-based exercises.

Pre-Requisites

Co-Requisites


Lectures 1Seminars








BS1010 I.T. and Numeracy Skills for Biologists A




001 Coursework (Final) 100



Intended Learning OutcomesOn completion of this module, students are expected to be able to:

* Apply a methodical approach to the solution of numerical problems in the context of biological sciences. * Demonstrate the capacity to apply mathematical, statistical and data handling techniques appropriate to the BiologicalSciences degrees. * Demonstrate the capacity to access scientific literature via online bibliographic databases. * Demonstrate the acquisition of skills and attributes necessary for lifelong learning, including the use of C&IT, the capacityto access a variety of resource materials and effective time management.

Teaching and Learning Methods1 lecture, 19 computer practical classes, directed reading.

Assessment MethodsComputer-based exercises.

Pre-Requisites

Co-Requisites


Lectures 1Seminars








BS1011 I.T. and Numeracy Skills for Biologists B




001 Practicals 30003 Examination (Final) 70 1

Period: Semester 1Occurence: ACoordinator: Richard GornallMark Scheme: UG Pass for Credit



Period: Semester 1Occurence: ECoordinator: Richard GornallMark Scheme: UG Pass for Credit


005 Practicals 30008 Open Book Examination (Final) 70 1

Period: Semester 1Occurence: E2Coordinator: Richard GornallMark Scheme: UG Pass for Credit


Lectures 15Seminars








BS1012 Animal and Plant Diversity



Intended Learning OutcomesAt the end of this module typical students should be able to describe and discuss: • the outline life-cycles of the major groups of plants, the origins of the land flora, the seed habit and the evolution of floweringplants; • flowering plant reproductive biology; • the importance of hybridisation and polyploidy in plant evolution; • the major patterns of body plan found in animals; • the relationships between and within the major invertebrate phyla; • the classification of the major animal groups; • basic phylogeny; • animal origins and the cambrian explosion; • the importance of the coelom in animal diversity.

Key skills that should be acquired include the ability to: give an oral presentation; write a relevant, coherent essay; search thelibrary and other sources for relevant information; conduct laboratory work, including the dissection of biological specimensproficiently and safely; write an accurate laboratory report; work as part of a team.

Teaching and Learning MethodsLectures, Tutorials, Laboratory practical classes, Private Study

Assessment MethodsEssays, Written reports, Reviews, Tutorial presentations. Short answer examination.



Pre-Requisites

Co-Requisites


BS1012 Animal and Plant Diversity




001 Practical Reports 20002 Essay 7003 Presentation 3004 Examination (Final) 70 1

Period: Semester 2Occurence: ACoordinator: Paul JarvisMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module, typical students should be able to: (1) Explain how animals and plants acquire and assimilateenergy and understand the main physiological processes in plants and animals. (2) Design and interpret experiments toinvestigate the acquisition of light energy and its transduction and utilisation in plants, and the utilisation of primary andsecondary production by animals. (3) Present scientific information in oral and written form.

Teaching and Learning MethodsLectures, directed reading, laboratory practical classes.

Assessment MethodsEssays, Written reports, Reviews, Tutorial presentations. Short answer examination.



Pre-Requisites

Co-Requisites


Lectures 15Seminars








BS1013 Animal and Plant Physiology




001 Essay 10002 Tutorial participation 5003 Practicals 15004 Online Assessment 10005 Examination (Final) 60 2

Period: Semester 1Occurence: ACoordinator: Christopher WillmottMark Scheme: UG Pass for Credit


007 Essay 10008 Tutorial participation 5009 Practicals 15010 Online Assessment 10011 Examination (Final) 60 2

Period: Semester 1Occurence: ECoordinator: Christopher WillmottMark Scheme: UG Pass for Credit


Intended Learning OutcomesBy the end of this module students should have an understanding of: the structures of biological macromoleculesand their components, the principles and mechanisms of information transfer from DNA to proteins, the basicprinciples of enzyme catalysis, the relationship between structure and function for some proteins and for cellmembranes, key metabolic processes, the molecular basis of some medical conditions and some drug actions.Students should also be able to: participate effectively in a range of teaching and learning activities, combine factsand ideas in clear and concise written and oral communications, demonstrating basic biochemical laboratory skillsusing safe laboratory practice, and demonstrate core data-handling skills.

Teaching and Learning MethodsLectures, practicals, work sessions and tutorials

Lectures 30Seminars








BS1015 Introduction to Biochemistry



Assessment MethodsContinuous assessment work (to include practical write-ups, computer based test on practical work, essay and oralpresentation). Examination (2 hours).



Pre-Requisites

Co-Requisites


BS1015 Introduction to Biochemistry




001 Assessment by attendance only (Final) 100

Period: Semester 1Occurence: ACoordinator: Jon ScottMark Scheme: UG Attendance Only


Intended Learning OutcomesBy the end of the module, students should be able to: utilise different planning and organisational strategies to improve theeffectiveness of their learning take concise notes from lectures and written sources and use these notes to underpin theirindependent study communicate scientific material effectively in writing and orally explain the rationale of experimentaldesign and the structure of scientific papers identify strategies to support their on-going development as learners.

Teaching and Learning MethodsLectures, practical exercises, directed reading of study guides.

Assessment MethodsFormative assessment will be provided through the tutorials and coursework of 1st semester modules.

Pre-Requisites

Co-Requisites


Lectures 8Seminars

Practical Classes & WorkshopsTutorials 4







BS1020 Study and Communication Skills




001 Practical Reports 30002 Examination (Final) 70 3

Period: Semester 1Occurence: ACoordinator: Raymond DalgleishMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn completion of the module students should be able to:Describe how prokaryotic and eukaryotic genomes are organised and discuss the mechanisms operating to influence thisorganisation. Describe the basic processes of DNA replication, recombination and repair. Carry out a variety of moleculartechniques and use them in the design of experiments to address problems relating to genome research. Work as a group toresearch problems. Organise written and oral presentations of research findings.

Teaching and Learning Methodspproaches used include lectures, practical sessions, tutorials and discussion groups.

Assessment MethodsPractical reports including aspects of experimental design. One three hour paper with essay style questions. Exhangestudents (Erasmus and JYA) are assessed by their coursework only.



Pre-Requisites

Co-Requisites


Lectures 30Seminars








BS2009 Genomes




001 Practical Work 20002 Essay 5003 Oral Presentation 5004 Examination (Final) 70 3

Period: Semester 1Occurence: ACoordinator: Peter AndrewMark Scheme: UG Pass for Credit


006 Practical Work 20007 Essay 5008 Oral Presentation 5009 Examination (Final) 70 3

Period: Semester 1Occurence: ECoordinator: Peter AndrewMark Scheme: UG Pass for Credit


006 Practical Work 20007 Essay 5008 Oral Presentation 5010 Open Book Examination (Final) 70 2

Period: Semester 1Occurence: E2Coordinator: Peter AndrewMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of the module, typical students should be able to: Explain basic techniques for isolation, handling and identificationof bacteria and demonstrate an ability to apply these techniques in the laboratory. Explain the diversity of the mechanisms forenergy generation by bacteria. Describe ways in which genetic techniques can be applied to the study of bacteria andapplications of these techniques in biotechnology. Describe the salient features of selected groups of bacteria. Describeuses of bacteria in industrial processes. Describe basic themes in bacterial infectious diseases.









BS2010 Microbiology I



Teaching and Learning MethodsLectures, Tutorials, Directed reading, laboratory practical classes, Field course.

Assessment MethodsOral presentation, Essay examination, Laboratory reports



Pre-Requisites

Co-Requisites


BS2010 Microbiology I




001 Essay under exam conditions 10002 Practical report 10003 Tutorials 10004 Examination (Final) 70 3

Period: Semester 1Occurence: ACoordinator: Richard EvansMark Scheme: UG Pass for Credit


006 Essay under exam conditions 10007 Practical report 10008 Tutorials 10009 Examination (Final) 70 3

Period: Semester 1Occurence: ECoordinator: Richard EvansMark Scheme: UG Pass for Credit


006 Essay under exam conditions 10007 Practical report 10008 Tutorials 10010 Open Book Examination (Final) 70 3

Period: Semester 1Occurence: E2Coordinator: Richard EvansMark Scheme: UG Pass for Credit


Lectures 25Seminars








BS2013 Physiology and Pharmacology 1



Intended Learning OutcomesOn completion of the module, students should be able to: describe the basic structure of the various classes of cellsurface receptors, explain the intracellular signalling pathways regulated by such receptors, provide examples ofreceptors that possess multiple subtypes for a given hormone or neurotransmitter (agonist) and discuss thephysiological basis for this, undertake a quantitative analysis of drug-receptor interactions and interpret theinformation, understand how drugs can modify agonist-receptor interactions and be able to quantitative theseeffects, discuss the mechanisms by which drugs can modify the function of the cardiovascular system to treatdisease states such as hypertension, have an understanding of basic endocrine control mechanisms, describe theendocrine events associated with the hpothalamo-pituitary axis, have an understanding of the endocrine pancreasand insulin, discuss reproduction and reproductive endocrinology, work effectively within a group to performexperiments that address the sites and mechanisms of drug action.

Teaching and Learning MethodsLectures, tutorials and Laboratory practical classes

Assessment MethodsPractical report, tutorial presentation, essay, examination



Pre-Requisites

Co-Requisites






001 Essay 10002 Practical Report 13003 Test on practical component, Tutorial worksheets, attendance,

participation7

004 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Gary WillarsMark Scheme: UG Pass for Credit


006 Essay 10007 Practical Report 10008 Test on practical component, Tutorial worksheets, attendance,

participation10

009 Examination (Final) 70 3

Period: Semester 2Occurence: ECoordinator: Gary WillarsMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module students should be able to: distinguish the different cell types present in the peripheral and centralnervous system and outline the mechanisms by which the central and peripheral nervous systems form; demonstrate themany properties of ion channels and how they contribute to the resting membrane potential and the propagation of the actionpotential; distinguish between voltage- and ligand-gated ion channels; explain the mechanisms by which nervous impulsesare conducted along the axons of myelinated and unmyelinated axons; explain the basic molecular mechanisms underlyingchemical transmission in the nervous system; demonstrate how action potentials and voltage-sensitive calcium channelsregulate neurotransmission; demonstrate the basic mechanism by which neurones communicate, e.g. synaptic transmissionand electrical coupling; demonstrate how synaptic information is integrated; distinguish the different types of cell surfacereceptor for neurotransmitters and hormones, demonstrate how ion channels and cell surface receptors contribute to cellfunction in physiological systems, e.g. the retina and auditory systems; demonstrate the nature of the molecular targets usedin the treatment of specific CNS disorders and how the function of these targets can be pharmacologically manipulated

Teaching and Learning MethodsLectures, tutorials and laboratory practical classes

Lectures 27Seminars











Assessment MethodsEssay, practical report, practical test, examination



Pre-RequisitesBS2013

Co-Requisites






001 Essay 15002 Lab Reports 5003 Practical Examination (Final) 80 3

Period: Semester 1Occurence: ACoordinator: Richard GornallMark Scheme: UG Pass for Credit


Intended Learning OutcomesThrough a combination of lectures, laboratory classes and field-based classes, students will be taught how to identify a rangeof common flowering plant families and species, recognised in the context of our current understanding of their evolutionaryrelationships. By the end of this module, students should be able to:demonstrate an understanding of the major plant groups and their evolutionary relationships;be familiar with the different types of identification key, know how to use them, and understand the relative merits of each;understand botanical terminology and the nature of diagnostic characters; identify reliably any land plant to the level of class;identify reliably at least 36 of the commoner flowering plant families found wild in the British Isles.

Successful completion of the module provides the necessary training in order to: Undertake an ecological survey researchproject in the 3rd yea, during which species identification skills will be honed; sit the exam for a Field Identification KillsQualification (FISQ), a professional qualification validated by the Botanical Society of the British Isles.

Teaching and Learning MethodsLectures, tutorials, and laboratory practical classes.

Assessment MethodsExamination; essay; laboratory practical reports.

Pre-Requisites

Co-Requisites


Lectures 18Seminars








BS2018 Plant Identification Skills




001 Practical Report 15002 Essay 15003 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Shaun HeaphyMark Scheme: UG Pass for Credit


001 Practical Report 15002 Essay 15003 Examination (Final) 70 3005 Practical Report 15006 Essay 15007 Examination (Final) 70 3

Period: Semester 2Occurence: ECoordinator: Shaun HeaphyMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module, typical students should be able to: Describe major features of immunology, virology and eukaryoticmicrobiology. Conduct simple microbiological procedures. Present and interpret laboratory results. Have demonstratedcompetence in acquiring information from the scientific literature, both in its printed and electronic form and to present it in awritten form. Have practiced key IT skills such as word processing. Work effectively in groups. Demonstrate effective timemanagement.

Teaching and Learning MethodsLectures, Tutorials, Directed reading, Problem solving classes, Laboratory practical classes, Field course.

Lectures 31Seminars








BS2024 Microbiology II



Assessment MethodsEssays, Essay examinations, Laboratory reports.



Pre-Requisites

Co-Requisites


BS2024 Microbiology II




001 Essay 10002 Poster session 20003 Animal development practicals 15004 Plant development practicals 15005 Examination (Final) 140 3

Period: Semester 1Occurence: ACoordinator: Jonathan McDearmidMark Scheme: UG Pass for Credit


007 Essay 10008 Poster session 20009 Animal development practicals 15010 Plant development practicals 15011 Examination 140 3

Period: Semester 1Occurence: ECoordinator: Jonathan McDearmidMark Scheme: UG Pass for Credit


007 Essay 10008 Poster session 20009 Animal development practicals 15010 Plant development practicals 15012 Open Book Examination (Final) 140 3

Period: Semester 1Occurence: E2Coordinator: Jonathan McDearmidMark Scheme: UG Pass for Credit


Lectures 24Seminars








BS2025 Developmental Biology



Intended Learning OutcomesAt the end of the module students should be able to:

Describe and compare the life cycle of various animals and plants from fertilization through to maturation; Discuss theexperimental approaches scientists use to study embryonic development, with particular emphasis on molecular genetictechniques; Explain the importance of cell-cell interactions during animal development; Discuss how differential geneexpression is fundamental to the developmental process; Describe the mechanisms that regulate gene expression duringdevelopment; Explain embryonic polarity systems and the importance of cell lineage and position in embryonic patternformation.

Teaching and Learning MethodsLectures, Practical classes, Tutorial poster session, Mock examination tutorial.

Assessment MethodsExam: 3 hour written examination comprising one short answer section and two written essays. Continuous assessment: Four practical reports, one essay and one poster presentation.



Pre-Requisites

Co-Requisites


BS2025 Developmental Biology




001 Experimental analysis 15002 Essay 15003 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Frederick TataMark Scheme: UG Pass for Credit


005 Experimental analysis 15006 Essay 15007 Examination (Final) 70 3

Period: Semester 2Occurence: ECoordinator: Frederick TataMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module, a typical student should be able to:-Explain the use of genetics to dissect gene regulation + function during development-Describe how genetics is used to study human disease and might be used for treatment-Analyse human pedigrees to determine inheritance patterns of genes-Determine genetic distances using linkage analysis-Explain the use of population genetic analysis-Devise models to explain mutant phenotypes in terms of gene function or regulation-Relate disruptions in the genome to expression of diseases and mutant phenotypes -Describe human sex chromosomes and explain sex determination mechanisms in a variety of species.

Teaching and Learning MethodsLectures and directed reading; experimental practicals and analyses; problem-solving tutorials.

Lectures 26Seminars








BS2026 Genes, Development and Inheritance



Assessment MethodsEssay; experimental analysis; examination.



Pre-Requisites

Co-Requisites


BS2026 Genes, Development and Inheritance




001 Practical reports 30002 Examination (Final) 70 2

Period: Semester 1Occurence: ACoordinator: Nickolai BarlevMark Scheme: UG Pass for Credit


004 Practical reports 30005 Examination (Final) 70 2

Period: Semester 1Occurence: ECoordinator: Nickolai BarlevMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn completion of the module students should be able to:• describe how the information encoded in DNA is transcribed into RNA and how primary transcripts are processed to achievetheir final, functional form;• demonstrate an appreciation of the principles of the genetic code and the translation of genetic information from messengerRNA into protein;• explain the mechanisms responsible for the regulation of gene expression in prokaryotes and eukaryotes;• explain the relationship between the organisation of genes and the mechanisms by which they are expressed;• carry out and interpret simple experiments illustrating aspects of the above

Teaching and Learning MethodsLectures, practicals, tutorials

Assessment MethodsWritten examination, practical reports



Pre-Requisites

Lectures 15Seminars








BS2052 From Genes to Proteins



Co-Requisites


BS2052 From Genes to Proteins




001 Literature Search 25002 Experimental Design 25003 Bioethics Report 25004 Presentation (Final) 25

Period: Semester 2Occurence: ACoordinator: Jon ScottMark Scheme: UG Pass for Credit


005 Literature Research 25006 Experimental Design 25007 Bioethics Report 25008 Presentation (Final) 25

Period: Semester 2Occurence: ECoordinator: Jon ScottMark Scheme: UG Pass for Credit


Intended Learning OutcomesStudents should be able to:Search for information effectively using on-line data basesDesign an experiment including selection of appropriate sampling techniques and estimation of the numbers of replicatesrequiredAppreciate the ethical implications and associated legal requirements of different types of biological researchCritically evaluate research literatureInterpret and present experimental data in writing and using oral and poster presentations.

Teaching and Learning MethodsLectures, workshops, directed reading

Assessment MethodsLiterature searching exercise, experimental design in-course test, bioethics report, poster presentation

Pre-Requisites

Co-Requisites









BS2060 Research Skills




BS2060 Research Skills




001 Practical reports 60002 Examination (Final) 40 1.5

Period: Semester 1Occurence: ACoordinator: Richard BadgeMark Scheme: UG Pass for Credit


004 Practical Reports 60005 Examination (Final) 40 1.5

Period: Semester 1Occurence: ECoordinator: Richard BadgeMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module, typical students should be able to: At the end of this module, typical students should be able to:Access and search bioinformatic databases to address specific biological hypotheses. Retrieve and utilize bioinformatic data(chiefly DNA and protein sequences). Compare DNA and protein sequences to analyse gene structure and function. Outlinethe methods and technologies by which genomes are sequenced. Identify and discuss the ramifications of genome projectse.g. transcriptomics, proteomics. Describe the informatic challenges faced when integrating genome, transcriptome andproteome scale datasets. Use phylogenetics methods to examine the evolutionary relationships between organisms.

Teaching and Learning MethodsLectures, tutorials, practical classes

Assessment MethodsPractical reports, examination



Pre-Requisites

Lectures 15Seminars








BS2064 Bioinformatics of Genes



Co-Requisites


BS2064 Bioinformatics of Genes




001 Essay 10002 Locust neurobiology practicals 10003 Neural network simulation practicals 10004 Examination (Final) 70 3

Period: Semester 1Occurence: ACoordinator: Tom MathesonMark Scheme: UG Pass for Credit


006 Essay 10007 Locust neurobiology practicals 10008 Neural network simulation practicals 10009 Examination (Final) 70 3

Period: Semester 1Occurence: ECoordinator: Tom MathesonMark Scheme: UG Pass for Credit


006 Essay 10007 Locust neurobiology practicals 10008 Neural network simulation practicals 10010 Open Book Examination (Final) 70 3

Period: Semester 1Occurence: E2Coordinator: Tom MathesonMark Scheme: UG Pass for Credit


Intended Learning OutcomesUpon completion of this module students should be able to:

Discuss the principles of neuronal organisation that govern different types of sensory processing; Explain how learning andmemory shape behaviour, and explain the molecular and cellular bases of these phenomena; Describe how individualneurones and networks of neurones act together to generate patterned motor outputs that permit animals to interact with theircomplex and dynamic environment; Explain how experience shapes development of neural circuits within the brain.

Lectures 24Seminars








BS2066 Behavioural Neurobiology



Teaching and Learning MethodsLectures, Practical classes, Independently researched essay.

Assessment MethodsExam: 3 hour written examination comprising one short answer section and two written essays. Continuous assessment: Two practical reports and one independently research essay.



Pre-Requisites

Co-Requisites


BS2066 Behavioural Neurobiology




001 Field course reports (Final) 40002 Examination (Final) 60 3

Period: Semester 2Occurence: ACoordinator: John BaileyMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of the module students should be able to:- describe and explain species concepts and speciationmechanisms, the latter with particular reference to evolution in island gene pools; describe the significance ofreproductive isolation and its cytological background; describe and explain how differentiation and adaptiveradiation occur, especially in an island context; construct phenetic and phylogenetic trees, and produceclassifications; assess and unfamiliar island biota in the field in relation to its biogeography, evolution andtaxonomy, with due regard to safety, risk assessments and legal requirements relating to conservation; design,execute, analyse and write up field-based experiments, and prepare and deliver oral and written reports; collect,prepare, document and identify biological specimens.

Teaching and Learning MethodsLectures, tutorials, seminars, laboratory practical classes, demonstrations, field course, project supervision.

Assessment MethodsEssays, written reports, individual research projects, seminar presentation, short-answer/essay/problem-basedexaminations,. Laboratory reports, field reports, problem-based exercises.

Pre-Requisites

Co-Requisites


Lectures 15Seminars


Fieldwork 72Project Supervision






BS2070 Island Biology and Speciation




001 Practical 20002 Essay 10003 Examination (Final) 70 3

Period: Semester 1Occurence: ACoordinator: Eamonn MallonMark Scheme: UG Pass for Credit



Period: Semester 1Occurence: ECoordinator: Eamonn MallonMark Scheme: UG Pass for Credit



Period: Semester 1Occurence: E2Coordinator: Eamonn MallonMark Scheme: UG Pass for Credit


Lectures 30Seminars








BS2071 Evolution in Health and Disease



Intended Learning OutcomesAt the end of the course students should be able to: • understand how natural selection works• explain the distinction between proximate and ultimate explanations and how they combine to explain traits• understand that evolution is not just natural selection but includes also gene drift, gene flow, founder effects and speciation• explain how group selection being weak is a poor explanation for traits found during this course such as aging.• explain the evolutionary theory behind why virulence evolves• explain how genomic conflicts can elucidate both the evolution of cancer and numerous pregnancy related conditions• understand that each human has a slightly different genetic makeup - This leads to important differences in the way that individuals react to drugs and to disease.The practical classes should enable students to:• model natural selection• model SIR models of infectious disease spread and HIV dynamics during early infection using modelling software.• analyse the evolution of immunological proteins• understand the often complicated life cycles of parasites

Teaching and Learning MethodsLECTURES:There will be 30 lectures. They can be broken down into four major areas.• Evolutionary basics Adaptive evolution Neutral evolution The genetic impact of selection on populations The origin and maintenance of genetic variation The importance of development in evolution The expression of variation Sexual selection Genomic conflict Coevolution

• Infectious diseases Parasite host coevolution Parasite effects on the host Evolution of virulence Vaccination Antibiotic resistance Parasites and sex Parasites and humanity Whole genome analysis of parasite evolution Emergence of new infectious diseases • Non-infectious diseases Cancer Aging Syndrome X Evolutionary conflicts of pregnancy • Variation in health Medically relevant variation in the human genome Human behavioural ecology MHC

PRACTICALS: There will be five practical classes (total 15Hrs):• Haploid and Diploid models of Natural selection• SIR modelling of infectious disease• Early dynamics of HIV• Phylogeny of Immunological Proteins• The life cycle of the cestode Schistocephalus solidus, and its effects on an intermediate host, the three spined stickleback.




Assessment Methods• Practicals - 20%• Essay - 10% This will be a 1500 word essay, chosen from a predefined list.• Written 3 h examination in January - 70%



Pre-Requisites

Co-Requisites

Excluded CombinationsBS2052, BS2064





001 Field Reports 35002 Posters 5003 Practical Reports 10004 Examination (Final) 50 2

Period: Semester 1Occurence: ECoordinator: David HarperMark Scheme: UG Pass for Credit



Period: Semester 2Occurence: ACoordinator: David HarperMark Scheme: UG Pass for Credit



Period: Semester 2Occurence: ECoordinator: David HarperMark Scheme: UG Pass for Credit










BS2081 Ecology and Biodiversity



Intended Learning OutcomesThe first half of the module is based on active fieldwork where students will:- discuss the basic principles of ecology and apply these principles to aquatic and terrestrial ecosystems- interpret the processes, both biotic and abiotic, that affect natural populations and communities.- execute a range of field ecology techniques relevant to terrestrial, marine and freshwater communities.- collect, prepare, document and identify animal and plant species; measure biodiversity within a range of terrestrial andaquatic communities.

The second half of the module explores the theory behind the issues of conservation biology such as policies, threats andtechnological advances. Students will:- describe and assess advances in molecular methods to measure biodiversity and to how these technologies apply toecological studies- identify why we must maintain biodiversity levels to sustain valuable habitats and enhance human health; - discuss the main challenges to maintaining biodiversity e.g., agriculture, invasive species and climate change; - discuss biodiversity in relation to (i) food security (crops and livestock and their domestication), (ii) environmental adaptationand (iii) medicine; - describe how and what types of genetically modified organisms (GMOs) are produced and assess their relevance and value.Throughout the module, students will also:- write concisely in a competent scientific style and carry out basic numerical analysis.

Teaching and Learning MethodsLecturesPractical classesDirected reading SeminarsField observations & recording.

Assessment MethodsField reports in the form of research papers Practical reportsPoster presentation and media report on recent research in biodiversity and conservationShort answer examination questionsEssay examination questions

Pre-Requisites

Co-Requisites


BS2081 Ecology and Biodiversity





Period: Semester 1Occurence: ACoordinator: Nickolai BarlevMark Scheme: UG Pass for Credit


Intended Learning OutcomesBy the end of the module participating students should be able to: describe the molecular mechanisms of protein-protein andprotein-DNA interactions; give an overview of gene regulation in prokaryotes, including (i) promoter recognition and initiationof transcription, (ii) control of bacterial operon transcription using various examples, (iii) control of viral transcription. -Describe transcription regulation in eukaryotes (i) organisation of eukaryotic genes and implications of the nucleus forexpression, (ii) chromosome structure, (iv) pre-mRNA splicing, (v) modifications of mRNA and rRNA in eukaryotes. Describethe mechanisms of translation (i) structure and role of tRNA, (ii) ribosome-mRNA interaction, (iii) initiation, elongation andtermination of translation. Explain the role of post-translational modifications in regulation of proteins functions and stability.Describe the principles of protein folding. Apply practical techniques appropriate for studying lac operon induction in bacteriaand transcription/splicing in vitro. Demonstrate data-handling and interpretation skills.

Teaching and Learning MethodsThe module comprises lectures, practicals and small discussion groups (tutorials)

Assessment MethodsContinuous assessment (practical) work will count for 30% of the final mark . The final examination paper (3 hrs) will count for70%.



Pre-Requisites

Co-Requisites


Lectures 30Seminars








BS2091 Biochemistry I: From Genes to Proteins




001 Practicals 20002 Essay under exam conditions 10003 Examination (Final) 70 3

Period: Semester 1Occurence: ACoordinator: Sue ShackletonMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of the module, successful students will be able to: - Describe the techniques used to study (i) the ultrastructure ofthe cell (ii) protein-protein interactions in cells (iii) protein localisation and (iv) the dynamic properties of cellular components. -Give an overview of antibody production and use in immuno-microscopy assays. - Describe the ways that proteins and lipidsare organised in membranes. - Explain how membrane and secreted proteins are (i) synthesised in the endoplasmic reticulum(ii) are subject to quality control (iii) are post-translationally modified in the Golgi (iv) are transported to and from varioussubcellular compartments under the control of small GTP-binding proteins and (v) are targeted for degradation in lysosomesand proteasomes. - Describe the role of microtubules and the actin cytoskeleton in cellular processes such as vesiculartransport and cell polarity. - Describe the mechanisms by which cells communicate over short and long distances, and thesignalling pathways involved. - Discuss the basic principles of the regulation of cell proliferation including the role of cyclin-dependent kinases and cell cycle checkpoints. - Develop a strategy to address a specific scientific hypothesis and be able (i)to carry out some of the experimental methods required and (ii) to critically analyse the results of such experiments. - Write awell-presented, structured and well-reasoned essay on the topics covered in the module.

Teaching and Learning MethodsThe module comprises lectures, practicals and small group teaching, including one essay-writing session under examconditions.

Assessment MethodsContinuous assessment work will count for 30% of the final mark (practical work 20%, essay 10%). The final examinationpaper (3 hrs) will count 70%.



Pre-Requisites

Co-Requisites

Lectures 30Seminars








BS2092 Biochemistry II: Molecular Cell Biology




BS2092 Biochemistry II: Molecular Cell Biology




001 Practical 10002 Computer-based class 10003 Tutorial 10004 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Ralf SchmidMark Scheme: UG Pass for Credit


Intended Learning OutcomesBy the end of this module students should be able to: describe the pathways involved in the catabolism of dietary carbohydrates and lipids; give an overview of how metabolism isregulated as a consequence of metabolic demand; explain how defects in metabolic control mechanisms can lead to diseasestates; appreciate the special metabolic requirements of a cancer cell and how these determine tumour progression;appreciate methods used for studying metabolites; discuss the properties of enzymes and describe the different ways proteinactivity is regulated; appreciate the molecular mechanisms involved in energy transduction as shown by proteins involved inmovement, electron transport, ATP synthesis; apply practical techniques appropriate for the study of plasma lipoproteins;demonstrate data-handling and interpretation skills.

Teaching and Learning MethodsLectures, practical, tutorials, computer-based sessions, help sessions.

Assessment MethodsContinuous assessment work will count for 30 % of the final mark (practical 10%, computer-based class 10%, tutorial 10%).The examination paper (3 hrs) will count 70% of the final mark.



Pre-Requisites

Co-Requisites


Lectures 27Seminars








BS2093 Biochemistry III: Cellular Regulation of Energy and Metabolism




001 Essay 21002 Poster Presentation 9003 Examination (Final) 70 3

Period: Semester 1Occurence: ACoordinator: Charalambos KyriacouMark Scheme: UG Pass for Credit


001 Essay 21002 Poster Presentation 9003 Examination (Final) 70 3005 Essay 21006 Poster Presentation 9007 Examination (Final) 70 3

Period: Semester 1Occurence: ECoordinator: Charalambos KyriacouMark Scheme: UG Pass for Credit


005 Essay 21006 Poster Presentation 9008 Open Book Examination (Final) 70 3

Period: Semester 1Occurence: E2Coordinator: Charalambos KyriacouMark Scheme: UG Pass for Credit


Lectures 36Seminars








BS3000 Evolutionary Genetics



Intended Learning OutcomesStudents should understand the evolution of genes and genomes as well as appreciating the relevant roles of selection,migration and drift in shaping the genetic profiles of populations. This will be implemented through their ability to:1. Explain the evolution of life from simple RNA molecules2. Describe how bacterial evolution provides a model for understanding microevolution 3. Assess the use of phylogenies to answer more than just species topologies4. Explain the evolution of gene regulation with regard to developmental and behavioural genes5 Deduce models of human and primate evolution and genetic history6 Provide examples of where the study of ancient DNA has illuminated macroevolutionary events 7. Assess how changes in genetic variation caused by exposure to mutagens in the environment relate to future evolutionaryprocesses.

Teaching and Learning MethodsLectures, directed reading, essay, poster

Assessment MethodsEssay, poster presentation, examination

PLEASE NOTE: The examination for this module is scheduled in Midsummer (May/June).

ERASMUS AND STUDY ABROAD STUDENTSYear-long Erasmus and Study Abroad students are expected to take assessment pattern E1, which includes the exam, unlesstheir home University notifies us in writing that they are unable to attend during the exam period. In this case the students willthen take assessment pattern E2 (see below).

Erasmus Students and Study Abroad students attending for semester one only will be assumed to take assessment patternE2 along with students who qualify by the above criteria. All coursework assessments will be the same as AssessmentPattern E1 but an additional assessment will be set in lieu of the exam. The assessments will be returned as a singlecoursework mark.

Pre-Requisites

Co-Requisites

Excluded Combinations-BS3012, BS3054, BS3058, BS3064

BS3000 Evolutionary Genetics




001 Essay 20002 Tutorial Performance 10003 Examination (Final) 70 3

Period: Semester 1Occurence: ECoordinator: Andrew FryMark Scheme: UG Pass for Credit



Period: Semester 2Occurence: ACoordinator: Andrew FryMark Scheme: UG Pass for Credit



Period: Semester 2Occurence: ECoordinator: Andrew FryMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn completion of the module students should be able to: describe the main features which distinguish malignantcells from normal cells; describe the mechanisms which regulate the proliferation of normal cells including cellsignalling pathways, cell cycle control and apoptosis; explain how mutations in oncogenes and tumour suppressorgenes contribute to the malignant phenotype; describe the pathological processes of cancer cell metastasis andtumour angiogenesis; integrate information from diverse sources which have contributed to the understanding ofthe origins of human cancer; conduct a literature research project, and write a critical appraisal of the subject.

Teaching and Learning MethodsLectures, tutorials, computer practical class.

Lectures 30Seminars








BS3003 Cancer Cell and Molecular Biology



Assessment MethodsTutorial reports, computer practical report, essay, essay-based examination.




Co-Requisites


BS3003 Cancer Cell and Molecular Biology




001 Research Design and Analysis 30002 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Julie MorrisseyMark Scheme: UG Pass for Credit


004 Research Design and Analysis 30005 Examination (Final) 70 3

Period: Semester 2Occurence: ECoordinator: Julie MorrisseyMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn completion of the module students should be able to:- Provide detailed examples of genome diversity in microbes andexplain how such variation is generated. Describe in detail selected processes relating to replication, recombination, variationand expression of DNA as studied in yeast and bacteria. Design experimental strategies to solve problems in these areasusing a combination of genetics, biochemical and structural techniques. Communicate experimental strategies in writtenpresentations. Research the literature relevant to the topics concerned. Communicate database searches and reviews of theliterature in written presentations.

Teaching and Learning Methodsectures, tutorials, self directed learning associated with tutorial assignment.

Assessment MethodsThree hour examination with essay questions. Written assignments.



Pre-RequisitesBS2009 or BS2010

Lectures 36Seminars








BS3009 Genomics: a Microbial Perspective



Co-Requisites


BS3009 Genomics: a Microbial Perspective




001 Tutorials 20002 Debates 10003 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Ian EperonMark Scheme: UG Pass for Credit


Intended Learning OutcomesBy the end of this module students should be able to: Describe the principal components, both protein and RNA, involved intranscription, RNA processing and micro RNA action. Explain how these components act and interact during the variousreactions involved in gene expression. Describe the mechanisms by which the levels or sequences of the products areregulated. Review the main lines of evidence supporting the mechanisms proposed. Understand how these processes maycause or be altered in disease. Demonstrate in writing and in discussion their knowledge of current research methods andscientific reasoning by critical analysis of research papers.

Teaching and Learning MethodsLectures and tutorials.

Assessment MethodsFinal examination (70%), seminar debates (10%), written and oral work associated with tutorials (20%)



Pre-RequisitesBS2052 or BS2091

Co-Requisites










BS3010 Gene Expression: Molecular Basis and Medical Relevance




001 Essay under exam conditions 15002 Seminar and commentary 15003 Examination (Final) 70 3.25

Period: Semester 1Occurence: ACoordinator: Colin HewittMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module, typical students should be able to: Demonstrate a detailed knowledge of the mammalianimmune system, including specific and non-specific immune responses. Describe the molecular and genetic basisof strategies employed by microorganisms to invade host tissue, avoid host defence mechanisms and proliferate atsites of infection. Explain and appreciate the molecular and cellular approaches used to investigate infectious andimmunological diseases. Analyse and interpret information acquired from primary literature sources, then organiseand communicate it in oral and written form. Demonstrate in writing and orally, a capacity for critical analysis of aspecialised or topical issue of microbiology or immunology.

Teaching and Learning MethodsLectures, Seminars, Tutorial Exercises, Examination techniques, Directed reading.

Assessment MethodsEssay under exam conditions, Seminar presentations, Essay examinations.




Pre-Requisites

Co-Requisites










BS3012 Infection and Immunity




001 Essay 15002 Presentation 15003 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Martha ClokieMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn the completion of the module students should:• Be able to critically assess current views on the origins of life and the evolution of the major microbial taxa, drawing onevidence from the fossil record, abiogenic syntheses experiments and molecular evidence in gene sequence• Be able to identify the key roles played by microbes in the aquatic and terrestrial environment including soil structure,element cycles, metal extraction and human health.• Be able to evaluate important plant-microbe interactions such as the rhizobium-legume symbiosis and the possibilities formanipulating such systems to agronomic advantage• Be able to define the detrimental roles played by microbes in pollution and the beneficial roles played by microbes in wastewater treatment ,bioremediation and biofuel production• Have gained, in the context of the above areas of environmental microbiology, experience of accessing information from thescientific literature in electronic and written form, and its organisation through oral and written presentation.

Teaching and Learning MethodsThere are 29 lectures delivered on this couse by appropriate specialists.The non-lecture programme for Course BS3013 will consist of a seminar and an essay. There are no practicals.

The aim is to improve your communication skills, whilst at the same time improving your knowledge of material closely alliedto the lecture course.









BS3013 Environmental Microbiology



Assessment MethodsFor the seminar you will each prepare and present a 15 minute talk on an assigned topic, in front of the rest of yourcolleagues. The material will then be critically assessed by your colleagues and the academic staff. The seminar presentation will bemarked and account for 15% of the total marks available for BS3013. The essay on the subject matter of your seminar (2,000words) similarly accounts for 15% of your marks.Tutorial slots are available on demand in the summer term for discussion and clarification of course topics.




Co-Requisites


BS3013 Environmental Microbiology





Period: Semester 2Occurence: ACoordinator: Frederick TataMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module typical students should be able to:Describe the molecular mechanisms that link genes to development in the examples studied.Relate the experimental evidence to its interpretation.Explain the methods used to study gene function in model organisms.Devise experimental strategies for investigation of gene function and regulation during development.Interpret research publications and present interpretations in both written and oral forms.

Teaching and Learning MethodsLectures and guided reading, independent research of a specified topic, poster presentation.

Assessment MethodsPoster presentation, essay, examination.




Co-Requisites


Lectures 30Seminars






Total Module Hours


BS3018 Genes and Development





Period: Semester 1Occurence: ACoordinator: Nicola RoyleMark Scheme: UG Pass for Credit


Intended Learning OutcomesBy the end of the module students should be able to: explain the basis of genetic variation, how it arises and how itcan be used to analyse the genome. Describe the variety and complexity of the relationships between mutations inor near genes and the manifestation of a disease phenotype. Discuss the many ways that research in humangenetics can be used, e.g. to study evolution, in forensics, for diagnosis, for therapy. Conduct an independentliterature search on a topic of their choice and present their findings in written format; research in small groups andpresent their findings as a poster for discussion.

Teaching and Learning MethodsLectures, Student-lead seminars, Problem-solving tutorials, Directed learning, Self-directed learning.

Assessment MethodsEssay, poster presentation, essay, examination.




Pre-RequisitesBS2009, BS2026

Co-Requisites


Lectures 30Seminars








BS3031 Human Genetics




001 Group Presentation 10002 Essay 20003 Examination (Final) 70 3



005 Group Presentation 10006 Essay 20007 Examination (Final) 70 3

Period: Semester 2Occurence: ECoordinator: Jon ScottMark Scheme: UG Pass for Credit


Intended Learning OutcomesStudents should, in the light of current knowledge, be able to:

Describe the mechanisms of long-term potentiation and depression and their putative roles in learning and memory.Interpret the hierarchical and parallel processing of visual information by the brain and be able to relate this to the process ofimage extraction.Correlate the roles of the different brain structures involved in voluntary movement and be able to reconstruct, in overview,their interactions during movement generation.Describe some of the different approaches to investigating CNS function and compare their relative advantages anddisadvantages.Relate the role of integration within the CNS with particular reference to sensori-motor integration, higher functions such aslearning, memory and attention and to higher disorders of the CNS such as schizophrenia.Iindividually and in groups, discuss orally, or present in writing a critical analysis of a theory of some aspects of brain functionbased on the use of recent research reports.

Teaching and Learning MethodsLectures, practical classes, directed reading









BS3033 Brain and Behaviour



Assessment MethodsOral group presentation in the form of a critical review of a scientific programmeEssay of 2,500 words3 hr, essay-based examination



Pre-RequisitesBS2013, BS2014 or BS2066

Co-Requisites


BS3033 Brain and Behaviour




001 Essay Plan 5002 Essay 25003 Examination (Final) 70 3



001 Essay Plan 5002 Essay (3000 words) 25003 Examination (Final) 70 3

Period: Semester 2Occurence: ECoordinator: Alan CannMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module, typical students should be able to: Demonstrate an awareness of the main principles of Virology,having assimilated information on each of the major groups of vertebrate viruses and be able to explain the key concepts.Describe current key areas of advance in virology, including viruses and cancer, AIDS and prion diseases. Demonstrate thecapacity for critical scientific analysis of issues in Virology Access appropriate scientific literature and demonstrate thecapacity to analyse and criticise evidence gathered. Communicate in writing an awareness of concepts and debates inVirology Demonstrate the potential for life-long learning, use of C&IT, the capacity to access a variety of resource materialsand effective time management.

Teaching and Learning MethodsLectures, Tutorials, Directed Reading

Assessment MethodsEssay, Essay Examination



Lectures 30Seminars








BS3035 Virology




Co-Requisites


BS3035 Virology




001 Essay 30002 Dry-Practical Report 15003 Data Analysis 15004 Examination (Final) 140 3

Period: Semester 1Occurence: ACoordinator: John ChallissMark Scheme: UG Pass for Credit


Intended Learning OutcomesWhen a student has completed this module s/he should be able to (i) Describe the structure and function of components ofcell signalling cascades (e.g. G protein-coupled receptors (GPCRs)/receptor tyrosine kinases (RTKs), G proteins (monomericand heteromeric), enzymic and ion channel effectors), and how they interact with each other. (ii) Explain how receptors areregulated by pharmacological agents (e.g. agonists, antagonists, inverse agonists) that can act either orthosterically orallosterically. (iii) Provide a detailed contemporary account of the mechanisms of receptor desensitization / internalization /down-regulation and discuss the (patho)physiological and pharmacological significance of such regulation. (iv) Give examplesof signalling pathways, showing how they are structured (e.g. by compartmentation, scaffolding), their (patho)physiologicalfunction(s), and how therapeutic targets might be selected and pharmacologically manipulated. (v) Discuss, generally andthrough use of specific examples, the pharmacological manipulation of GPCR and RTK activities, ion channels andintracellular enzyme activities. (vi) Relate acute cell signalling events to long-term changes in cell phenotype and fate: thisshould include an explanation of cell surface-to-nuclear signalling and how changes in stimulation patterns or components ofsignalling pathways may regulate longer term (patho)physiological adaptations as might be observed in certain diseaseconditions (e.g. hypertrophic changes in cardiomyopathies). The student should also be able to analyse and interpretpharmacological experimental data and devise experimental strategies to address specific research questions.

Teaching and Learning MethodsLectures, tutorials, computer-based work-session

Assessment MethodsCoursework (30%): 2,000 word essay (preparation tutorial-supported); (computer-based) dry-practical report; data-analysisexercise (preparation tutorial-supported). Examination (70%): 3 essays chosen from approx. 8 topics on examination paper.




Lectures 30Seminars








BS3054 Molecular & Cellular Pharmacology



Pre-Requisites

Co-RequisitesBS2013, BS2014


BS3054 Molecular & Cellular Pharmacology




001 Essay 30002 Research paper 15003 Tutorials 15004 Examination (including 15mins reading time) (Final) 140 3.25

Period: Semester 1Occurence: ACoordinator: Robert FernMark Scheme: UG Pass for Credit


Intended Learning Outcomesa) Knowledge and understanding of biological facts, terms, principles, concepts, relationships, experimental techniques. b)Application of biological knowledge in constructing hyposeses, designing experiments and interpreting results; data handlingand evaluation of numeracal and non-numerical information; drawaing conclussion and making inferences; assessing thevalidity of expts, results, conclussion, inferences and statements; itendifying ambiguities, assumptions and mistakes. c)Coherent communication of biological information in continuous prose and by means of tables, diamgrams, drawings andgraphs.

Teaching and Learning MethodsLectures and tutorials.

Assessment MethodsCritical review, tutorial work and final exam





Co-Requisites


Lectures 31Seminars

Practical Classes & WorkshopsTutorials







BS3055 Molecular & Cellular Neuroscience




001 Practicals 15002 Essay 10003 Paper review 5004 Examination (including 15 minutes reading time) (Final) 70 3.25

Period: Semester 2Occurence: ACoordinator: Noel DaviesMark Scheme: UG Pass for Credit


Intended Learning OutcomesThe emphasis in this module will be on understanding the physiological role of cellular mechanisms in theregulation of the cardiovascular system. On completion of this module, students should be able to: Describe thecardiovascular system and appreciate the control systems involved in regulating the heart and the blood pressure.Describe the mechanisms of ion transport at the cell membrane and understand how ion channel structure relatesto function. Discuss the molecular processes involved in regulating ion channels and contractile proteins within thecardiovascular system. Describe the cellular mechanisms leading to the generation and regulation of the cardiacaction potential. Explain the mechanisms that lead to contraction of both cardiac and smooth muscle and howthese processes are controlled by the regulation of intracellular Ca2+. Discuss disorders of cardiac rhythm andunderstand the consequences of impaired blood supply (ischaemia). Discuss the mechanisms that regulatevascular function in relation to the control of blood flow and blood pressure. Discuss the mechanisms andimportance of receptor-operated Ca2+ increases in blood cells such as platelets and lymphocytes.

Teaching and Learning MethodsLectures, practical classes, tutorials.

Assessment MethodsEssay, paper review, practical report, examination.




Co-Requisites

Lectures 30Seminars



Guided Independent Study 112Demonstration 2





BS3056 Cellular Physiology of the Cardiovascular System




BS3056 Cellular Physiology of the Cardiovascular System




001 Fieldcourse Reports 25002 Essay 25003 Examination (Final) 50 2

Period: Semester 1Occurence: ACoordinator: David HarperMark Scheme: UG Pass for Credit


Intended Learning OutcomesBy the end of the module, students should be able to: 1) explain the legal and administrative basis for biodiversityconservation in the UK, Europe and internationally at species and ecosystem level; 2) interpret and evaluate the changes inhabitat structure in an ecosystem due to natural success, direct human impact or global-scale events; 3) evaluate themanagement of habitats in ecosystems in terms of the pereceived benefits for named species; 4) make a balancedassessment of the conflicts between conservation and other competing land uses; 5) write an assessment of the managementoptions available to move land uses towards a sustainable future; 6) understand what climate change is, what are its causesand its ecological effects.

Teaching and Learning MethodsLectures, seminars and fieldwork

Assessment MethodsWritten reports and web-based exercises. Essay and short answer examination questions


Pre-Requisites

Co-Requisites










BS3058 Ecology for Sustainability




001 Practical reports 15002 Tutorial essay 15003 Examination (Final) 70 3



Intended Learning OutcomesAt the end of the module students should be able to:• Relate eye design to differences in photic environment, particularly the role of light and dark adaptation.• Differentiate the types of imaging optics found in invertebrate and vertebrate eyes.• Compare the structures of specific vertebrate and invertebrate proprioceptors and correlate structure with function.• Compare the structures of specific vertebrate and invertebrate auditory organs, and correlate structure with function.• Describe the problems faced by animals in making aimed limb movements, and the neuronal mechanisms used toovercome them.• Compare neuronal population coding in both invertebrate and vertebrate sensory-motor systems.• Compare the neurophysiological basis of olfaction in vertebrates and invertebrates.• Execute experiments to investigate aspects of arthropod motor behaviour.• Analyse, and present a report on, experimental results interpreted within the context of research literature.

Teaching and Learning MethodsLectures, tutorials and laboratory practical classes.

Assessment MethodsCoursework essays, laboratory reports and essay examinations.




Pre-RequisitesBS2014 OR BS2066

Co-Requisites

Lectures 24Seminars








BS3064 Comparative Neurobiology




BS3064 Comparative Neurobiology




001 Field notebook (Final) 70002 Research Seminar 20003 Field and Lab Performance 10

Period: Semester 2Occurence: ACoordinator: Iain BarberMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the end of this module typical students should be able to: design a programme of fieldwork to test a hypothesisabout an aspect of animal behaviour; carry out the programme of field observations and quantitative data collection safely andefficiently; keep a detailed, reflective account of observations and data files in a field notebook, providing a complete record offieldwork and evidencing progression and development of scientific ideas; analyse data using appropriate statistical andgraphical techniques; present ideas verbally in a concise, clear and coherent manner and to interact with others in discussion.

Teaching and Learning MethodsSupervised and independent fieldwork, supervised laboratory work, library research, lectures, seminars and independentstudy

Assessment MethodsAssessment of field notebook, research seminar given on the research project undertaken during the module, performance inthe field


Co-Requisites










BS3066 Behavioural Ecology in Nature




001 Workshop Seminar 15002 Critical Literature Review 15003 Examination (Final) 70 2

Period: Semester 2Occurence: ACoordinator: Iain BarberMark Scheme: UG Pass for Credit


001 Workshop Seminar 15002 Critical Literature Review 15003 Examination (Final) 70 2005 Workshop seminar 15006 Critical literature review 15007 Examination (Final) 70 2

Period: Semester 2Occurence: ECoordinator: Iain BarberMark Scheme: UG Pass for Credit


Intended Learning OutcomesAfter completing the module and the assessment, students are expected to have covered sufficient material in lectures,workshops, research seminars and in their guided independent study to enable them to (1) Interpret accurately the findingsand limitations of research in three areas of current importance of animal behaviour (2) Summarise efficiently the results ofrecent published studies in both written and oral formats (3) Describe critically and coherently the importance of behaviouralbiology in contemporary scientific and lay society (4) Identify future research areas and the potential for collaboration withother branches of science.

Teaching and Learning MethodsA wide range of teaching approaches are used on the module. The first part of the module provides the student with a primeron modern approaches to the study of animal behaviour. Introductory lectures are given to introduce students to each of thesubsequent key topics, which are updated each year. Workshops cover topics such as reviewing current trends in animalbehaviour research, how to approach a scientiofic literature review and how to read a scientific paper. Supervised, student ledseminar sessions allow peer-teaching between group members, with recent research papers being presented to the group inoral formats. Journal clubs are also used to provide in depth covergae and stimulate debate about particualrly importantrecent papers. Finally research seminars, given by in-house or invited guest speakers give students the opportunity toexperience the excitement of scientific research at the frontiers of knowledge. .









BS3067 Current Research Topics in Animal Behaviour



Assessment MethodsFinal examination, oral presentation, critical literature review. Feedback on non-assessed formative oral presentations is alsoprovided.



Pre-Requisites

Co-Requisites


BS3067 Current Research Topics in Animal Behaviour




001 Poster Presentation 15002 Essay 15003 Examination (Final) 70 3

Period: Semester 1Occurence: ACoordinator: Primrose FreestoneMark Scheme: UG Pass for Credit


Intended Learning OutcomesDemonstrate an awareness of the importance of understanding microbial biochemistry and genetics in microbialbiotechnological processes. Describe the central theories and concepts of selected aspects of microbialbiotechnology. Develop skills in researching and reviewing the scientific literature, and then be able to organise andcommunicate it in oral and written form. Develop a reflective appreciation of the economic, social and ethical issuessurrounding uses of micro-organisms in industrial processes

Teaching and Learning MethodsThese will comprise lectures, tutorials, seminars, a short field trip to a local brewery, problem surgeries, and directed reading.

Assessment MethodsContinuous assessment will constitute 30% of the course marks, comprising: poster creation and oral presentation15% and course essay, 15%. Students will be assigned a topic upon which they are required to create and presenta poster and a 2000-word essay. The End of Module written examination (3 hours) will comprise 70% of the coursemark, and will consist of 2 sections: students answer 1 question out of 3 in section 1 and 2 questions out of 5 in section 2.





Co-Requisites










BS3068 Microbial Biotechnology



BS3068 Microbial Biotechnology




001 Computer-based analysis 10002 Computer practical 10003 Group Exercise 10004 Examination (Final) 70 3

Period: Semester 1Occurence: ACoordinator: Mark CarrMark Scheme: UG Pass for Credit


Intended Learning OutcomesPractically all events in cells depend on the existence of protein complexes which interact with other components tobring about diverse functions. The aim of this module is to provide an overview of functional protein complexeswithin cells, how such complexes are identified and how their mechanism of action can be understood at themolecular level.

Teaching and Learning MethodsLectures, practicals, tutorials

Assessment Methods70% examination, 30% coursework (comprising 3 equal elements: computer-based analysis of protein-ligand binding data,computer practical on protein NMR data analysis and interpretation, and a group exercise on literature interpretation andpresentation).





Co-Requisites


Lectures 31Seminars



Guided Independent Study 94Demonstration 1





BS3070 Protein complexes: from cells to molecules




001 Field Notebook 30002 Essay 20003 Examination (Final) 50 2

Period: Semester 1Occurence: ACoordinator: Edward GatenMark Scheme: UG Pass for Credit


Intended Learning Outcomes1. To learn to identify some of the major organisms in oceanic ecosystem. 2. To appreciate the problems of sampling organisms in the ocean and the methods used to obtain samples. 3. To understand the linkages between the components and the major barriers to distribution. 4. To understand the major issues that have to be dealt with when conserving or managing oceanic species.

Teaching and Learning MethodsThe emphasis of the course will be on field and practical lab work together with some self-directed student reading. Personal observation, sampling and analysis.

Assessment MethodsField Notebook and Essay Examination.


Pre-Requisites

Co-Requisites


Lectures 10Seminars








BS3071 Oceanic Biology: From Plankton to Whales




001 Practical Reports 20002 Seminar 10003 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Robert HammondMark Scheme: UG Pass for Credit


Intended Learning OutcomesThe aim of the course is for students to gain knowledge and understanding about up-to-date molecular methods and how theycan be used to answer important questions in ecology and evolution.Emphasis will be given to next generation sequencing (NGS) methods and how these are revolutionizing both ecological andevolutionary studies of non-model organisms and also of communities.

On completion of the course students are expected to be able to:-- describe the various types of molecular marker and their properties- with a knowledge of underlying theory, describe and explain how molecular markers can be used to:- - understand genome diversity and evolution (inc. chromosome evolution) - show adaptation at the molecular level - reveal intraspecific geographic patterns of genetic variation - analyse hybrid zones - investigate dispersal and gene flow - investigate mating systems, social structure and relatedness - quantify inbreeding - investigate cryptic community structure using environmental genomics- apply their knowledge of molecular markers to conservation and environmental issues.

Teaching and Learning MethodsLecturesLaboratory practical classesDirected reading, with particular emphasis on the primary literatureTutorials Student seminars (peer learning)









BS3073 Molecular Ecology and Evolution



Assessment MethodsSeminar presentationLaboratory reportsEssay/problem-based examination



Pre-Requisites

Co-Requisites


BS3073 Molecular Ecology and Evolution




001 Performance (Experimental) 25002 Oral Presentation 15003 Report (Experimental) (Final) 60

Period: Academic YearOccurence: ACoordinator: Martyn Mahaut-SmithMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn completion of the project, students are expected to be able to:- test a hypothesis by appropriate experimental or computer-based techniques; conduct experimental procedures and demonstrate good laboratory or bioinformatics practice;analyse and present experimental or bioinformatics data; locate appropriate literature sources and interpret their findings inrelation to other work in their subject area; discuss the project report and be aware of its wider context; present the keyfindings in the form of an oral presentation; produce a well written and presented dissertation that complies with the guidelinesfor presentation of the project.

Teaching and Learning MethodsDirected reading, Project supervision, Independent research.

Assessment MethodsOral presentation, assessment of performance, individual research projects, dissertation.

Pre-Requisites

Co-Requisites




FieldworkProject Supervision 15






BS3100 Research Project (Experimental)




001 Performance (Analytical) 15002 Oral Presentation 15003 Report (Analytical) (Final) 70

Period: Academic YearOccurence: ACoordinator: Martyn Mahaut-SmithMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn completion of the project students are expected to be able to:- conduct an in depth study to answer a specific question;undertake appropriate literature searches; assimilate information from a range of sources, and prepare their own synthesis ofthis information; analyse and interpret the information critically; discuss the project report and be aware of its wider context;present the key findings in the form of an oral presentation; produce a well written and presented dissertation that complieswith the guidelines for presentation of the project.



Pre-Requisites

Co-Requisites










BS3200 Research Project (Analytical)




001 Oral Presentation 15002 Reflective Journal 10003 Placement Assessment 10004 Supervisor Assessment 10005 Report 55

Period: Academic YearOccurence: ACoordinator: Christopher WillmottMark Scheme: UG Pass for Credit


Intended Learning OutcomesTo develop an awareness of how teaching is developed, delivered and evaluated in primary or secondary schools.To participate in a range of activities in the classroom and wider school (including, in some cases, the development, deliveryand evaluation of supervised teaching).To undertake a school-based research project connected with teaching and learning, present the key findings in the form ofan oral presentation, and produce a dissertation that discusses the project findings and wider context.

Teaching and Learning MethodsDirected reading, supervision by teacher (school) and supervisor (university), independent research.

Assessment MethodsPlacement assessment (teacher), project performance (supervisor), oral presentation (marking panel), reflective journal(supervisor and second marker), and final report (supervisor and second marker).

Pre-Requisites

Co-Requisites





Guided Independent StudyDemonstration 130


Placement 140Year Abroad



BS3300 Research Project (Education)




Period: Academic YearOccurence: ACoordinator:Mark Scheme: UG Pass for Credit


001 Laboratory performance 25002 Report 75

Period: Academic YearOccurence: E1Coordinator:Mark Scheme: UG Pass for Credit


003 Laboratory performance 100

Period: Academic YearOccurence: E2Coordinator:Mark Scheme: UG Attendance Only


Intended Learning OutcomesOn completion of the project, students are expected to be able to:- test a hypothesis by appropriate experimental or computer-based techniques; conduct experimental procedures and demonstrate good laboratory or bioinformatics practice;analyse and present experimental or bioinformatics data; locate appropriate literature sources and interpret their findings inrelation to other work in their subject area; discuss the project report and be aware of its wider context; produce a well writtenand presented dissertation that complies with the guidelines for presentation of the project.


LecturesSeminars








BS3901 Research Project



Assessment MethodsAssessment of performance, individual research projects, dissertation.

PLEASE NOTE: Applicants may only apply for this project if they can submit a letter of confirmation from an academic whohas agreed to supervise their project.

Your home university will be asked to confirm whether you should be assessed by Assessment Group E1 or E2. E2 is basedupon the assumption that the overall grading for your period of study will be determined via your report to your homeuniversity.

Pre-Requisites

Co-Requisites






Period: Semester 1Occurence: ACoordinator:Mark Scheme: UG Pass for Credit


001 Laboratory performance 25002 Report 75003 Laboratory performance 100

Period: Semester 1Occurence: ECoordinator:Mark Scheme: UG Pass for Credit


Period: Semester 2Occurence: ACoordinator:Mark Scheme: UG Pass for Credit


001 Laboratory performance 25002 Report 75003 Laboratory performance 100

Period: Semester 2Occurence: ECoordinator:Mark Scheme: UG Pass for Credit


LecturesSeminars












Teaching and Learning MethodsDirected reading, Project supervision, Independent research




Pre-Requisites

Co-Requisites






Period: Autumn TermOccurence: ACoordinator:Mark Scheme: UG Pass for Credit


Period: Spring TermOccurence: ACoordinator:Mark Scheme: UG Pass for Credit


Period: Summer TermOccurence: ACoordinator:Mark Scheme: UG Pass for Credit




LecturesSeminars






Total Module Hours








Pre-Requisites

Co-Requisites






003 Examination (Final) 100 1.5

Period: Semester 2Occurence: ACoordinator: Volko StraubMark Scheme: UG Pass for Credit


003 Examination (Final) 100 1.5

Period: Semester 2Occurence: ECoordinator: Volko StraubMark Scheme: UG Pass for Credit


Intended Learning OutcomesBy the end of this module, students should be able to: Describe membrane structure and function with particular reference tothe properties and functions of membrane lipids and proteins Discuss the movement of molecules across membranes interms of the activities of specific channels and pumps in the membrane Describe the basis of resting membrane potential andelectrical signalling in cells Give an overview of the role of membrane proteins as receptors for responding to external stimuli,and the uptake of external molecules via endocytosis Describe and compare biological communication processes involvinghormones, local mediators and neurotransmitters Describe the various receptor-effector mechanisms which influence thebehaviour of cells and explain the concepts of second messengers and cascades Give an overview of how recombinant DNAtechniques have been used to map function to structure in receptors and ion channels.

Teaching and Learning MethodsLectures, group worksessions, oral presentations, help sessions.

Assessment MethodsWritten examination



Pre-Requisites

Lectures 15Seminars








MB1004 Membranes and Receptors



Co-Requisites


MB1004 Membranes and Receptors




001 Practical Reports 10002 Poster 15003 Essay 15004 Examination (Final) 60 1.5

Period: Semester 2Occurence: ACoordinator: Annette CashmoreMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn completion of the module, students should be able to:Discuss the effects of mutations and how they arise; Explain how chromosomes are inherited through mitosis and meiosisand how genetic variation is generated; Carry out elementary genetic analysis and construct a simple linkage map; Describethe basic principles of gene cloning and the construction of gene libraries in bacteria;Construct simple restriction enzyme maps of DNA molecules; Discuss the incidence of genetic and genetically influenceddisorders; Describe methods of screening for genetic disorders; Describe the relationship between prevention and therapy forgenetic disease; Work in groups, researching a problem and delivering a poster presentation of the findings.

Teaching and Learning MethodsLectures, tutorials, practical classes

Assessment Methods1.5 hour examination; poster presentation, essay, reports of experiments carried out in practical classes



Pre-Requisites

Co-Requisites


Lectures 25Seminars








MB1005 Genes and Medicine




001 Lecture Summary (Qualifying Element) 10002 Course Essay (Qualifying Element) 30003 Presentation (Qualifying Element) 30004 News Discussion (Qualifying Element) (Final) 30



Intended Learning OutcomesBy the end of this module students will be able to: 1. Analyse the characteristics of writing styles from a range of differentpublications; 2. Identify the features and conventions of good scientific writing; 3. Identify key issues relating to writing withaccuracy and clarity; 4. Diagnose strengths and weaknesses in their own scientific writing; 5. Apply the features of goodscientific writing to their own work; 6. List key skills in making an orla presentation; 7. Prepare effective visual aids (e.g.powerpoint slides); 8. Analyse their own strengths and weaknesses so that they can develop effective means of verballyreporting the results of an experiment, or explain in an important scientific concept, taking into account the knowledge base ofthe audience; 9. Be able to critically evaluate media coverage of developments in biomedicine. These outcomes will beaddressed through engaging with topics from theappropriate medically-related discipline.

Teaching and Learning MethodsWriting tasks (2), essay, seminar presentation

Assessment Methods100% coursework (10% lecture summary, 30% "science in the news" questions, 30% essay, 30% talk)

Pre-Requisites

Co-Requisites










MB1030 Introduction to Medical Bioscience A




001 Scientific Report (Qualifying element) (Final) 25002 Essay (Qualifying element) 25003 Data-handling assessment (Qualifying element) 25004 Poster presentation (Qualifying element) (Final) 25



Intended Learning OutcomesBy the end of this module students will be able to: 1)demonstrate awareness of the key features of an effectiveessay-style examination answer 2) show how to construct a report to convey the results of a scientific investigation3) discuss the basis of scientific investigation in the context of analysing the behaviour of macromolecules such asproteins and nucleic acids 4) carry out basic numerical manipulations of scientific measurements, and criticallyanalyse experimental data 5) demonstrate knowledge about how to prepare a scientific poster. These outcomeswill be addressed through engaging with topics from the appropriate medically-related discipline.

Teaching and Learning MethodsLectures, group discussions, small group tutorials, peer review, formative help sessions, independent research.

Assessment MethodsScientific report, write-up of provided data in appropriate style; exam-style essay, 45 mins for essay under examconditions; Data-handling assessment, 75 minute paper of data interpretation questions; Poster presentation,single A1 poster prepared using Powerpoint.

Pre-Requisites

Co-Requisites


Lectures 8Seminars








MB1031 Introduction to Medical Bioscience B




001 Essay 15002 Practical Notebook 15003 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Galina MukamolovaMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the completion of the course students are expected:• describe the basic principles of microbial diagnostic• characterise major human pathogens and explain how they adapt to different environments• describe major infectious diseases and name corresponding causative agents• list major antimicrobials used for treatment of infectious diseases• explain important directions of public health microbiology• describe major areas of preventive treatment • conduct simple experiments for identification and characterisation of microorganisms of medical importance

Teaching and Learning MethodsLectures,directed reading, problem solving exercises, laboratory practical classes

Assessment MethodsCourse essay, written examination, laboratory reports.



Pre-Requisites

Co-Requisites










MB2020 Medical Microbiology




001 Written report 40002 Video production and presentation 20003 In-course SAQ assessment (Final) 40



005 Written report 40006 Video production and presentation 20007 In-course SAQ assessment (Final) 40

Period: Semester 2Occurence: ECoordinator: Christopher WillmottMark Scheme: UG Pass for Credit


Intended Learning OutcomesBy completion of the module students should be able to: Outline selected techniques, particularly those involvingrecombinant DNA technology and immunoassay, used in diagnosis and treatment of human disease. Give anoverview of the process involved in the generation of a pharmaceutical product. Discuss molecular aspects ofdrug design and therapeutic protein production. Consider the potential impact of the human genome-sequencingproject on the diagnosis and treatment of disease. Discuss the key social, and ethical issues related to areas suchas genetic screening, embryo research, animal experimentation and the production of pharmaceuticals. Work as ateam to design and present a video to discuss a specific bioethical issues. Critically review the informationavailable on a specific area of biology/medicine and summarise current knowledge in a written report.

Teaching and Learning MethodsLectures, computer-based sessions, tutorials, seminars, help sessions.

Assessment MethodsWritten report, video production/seminar presentation, In-course SAQ-based assessment.

Pre-Requisites

Co-Requisites










MB2050 Targeting Biochemical Knowledge to Medical Problems




001 Ethical matrix 10002 IT Exercises 10003 Website 30004 Dissertation (Final) 50

Period: Semester 2Occurence: ACoordinator: Christopher TalbotMark Scheme: UG Pass for Credit


005 Ethical matrix 10006 IT Exercises 10007 Website 30008 Dissertation (Final) 50

Period: Semester 2Occurence: ECoordinator: Christopher TalbotMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn completion of the module students should be able to:• Explain the scientific basis underlying current controversies in medical genetics.• Evaluate the arguments on both sides of an ethical topic• Outline the procedures in place for the establishment of laws and guidelines governing one of the areas listedabove.• Work as a team to produce a variety of presentations including websites and talks.

Teaching and Learning Methods Lectures, tutorials, computer class

Assessment MethodsIT exercises, website, dissertation (5000 words).

Pre-Requisites

Co-Requisites










MB2051 Current Issues in Medical Genetics



MB2051 Current Issues in Medical Genetics




001 Essay 1 25002 Essay 2 25003 Blackboard Assessment 10004 Examination (Final) 140 3

Period: Semester 2Occurence: ACoordinator: Steven EnnionMark Scheme: UG Pass for Credit


001 Essay 1 25002 Essay 2 25003 Blackboard Assessment 10004 Examination (Final) 140 3006 Essay 1 25007 Essay 2 25008 Blackboard Assessment 10009 Examination (Final) 140 3

Period: Semester 2Occurence: ECoordinator: Steven EnnionMark Scheme: UG Pass for Credit


Intended Learning OutcomesA range of disease states associated with core physiological systems and applicable to human medicine will be presented.Lectures in each area will give physiological, aetiological and epidemiological perspectives. The aim is to provide studentswith a sound understanding of how malfunction of the physiological system results in disease and to provide an appreciationof the significance of various disease states in terms of symptoms, prevalence, morbidity, mortality, risk factors andprevention strategies. Emphasis will also be made on understanding the physiological and biochemical basis of current andpossible future therapies. On completion of the module students should be able to: 1) Discuss the underlying anatomical,physiological and biochemical mechanisms and changes associated with the disease states covered. 2) Outline symptoms,prevalence, morbidity, mortality, and risk factors. 3) Critically evaluate the use of clinical findings and laboratory data in theidentification, aetiology and pathogenesis of selected diseases processes. 4) Discuss the physiological and biochemicalprinciples behind both current and potential future therapeutic strategies. 5) Make effective use of electronic sources ofinformation, including the PUBMED and OMIM databases and disease specific web sites, to find out detailed informationabout the physiology, aetiology and epidemiology of a particular disease.

Teaching and Learning MethodsThe course will be delivered by means of lectures supported by two tutorials and a computer based work session.

Lectures 29Seminars








MB2080 Pathophysiology of Disease



Assessment MethodsExamination (70%). Two Course essays (12.5% each). Blackboard based electronic assessment (5%).



Pre-Requisites

Co-Requisites


MB2080 Pathophysiology of Disease




001 Tutorials 20002 Essay 10003 Examination (Final) 70 3

Period: Semester 1Occurence: ACoordinator: Mark LeylandMark Scheme: UG Pass for Credit


Intended Learning Outcomes• Describe the factors that are involved in the development of inflammation and asthma.• Describe the molecular basis of complement activation and it’s role in disease.• Summarise the biochemical evidence linking changes in signalling pathways to hypertrophic growth in the failing heart.• Describe how mutations in sarcomeric and cytoskeletal proteins contribute to the development of cardiomyopathies• Discuss the molecular basis of laminopathies• Conduct a literature research project, and write a critical appraisal of the subject.• Critically evaluate scientific papers

Teaching and Learning MethodsLectures, tutorials, help sessions.

Assessment MethodsWritten examination, essay, tutorial work.




Pre-Requisites

Co-Requisites


Lectures 30Seminars








MB3001 Biochemical Mechanisms of Human Disease




001 Essay 15002 Case Presentation 15003 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Edouard GalyovMark Scheme: UG Pass for Credit


Intended Learning OutcomesAt the completion of the course students are expected:

• To be able to critically assess current views on the molecular mechanisms underlying bacterial virulence, drawing onevidence from the studies of host-pathogen interactions, immune responses, and lessons from history.• To be able to describe the key virulence factors and systems of major bacterial pathogens, and mechanisms of theiracquisition and exchange.• To be able to evaluate important host-microbe interactions such as bacterial invasion and intracellular life styles of differentbacterial pathogens • To be able to define host responses to bacterial infections and approaches used to create effective vaccines• Have gained, in the context of the above areas of microbiology, experience of accessing information from the scientificliterature in electronic and written form, and its organisation through oral and written presentation.

Teaching and Learning MethodsLectures, seminars, directed reading

Assessment Methods1 three hours exam paper, Essay, Case presentations



Pre-RequisitesMB2020

Co-Requisites










MB3020 Advanced Topics in Medical Microbiology



MB3020 Advanced Topics in Medical Microbiology





Period: Semester 2Occurence: ACoordinator: Christopher TalbotMark Scheme: UG Pass for Credit


Intended Learning Outcomes1. Outline the ways in which genetics is impacting on our knowledge, diagnosis and treatment of common diseasessuch as heart disease and Alzheimer’s disease.2. Describe how developments in gene mapping and analysis have benefited our understanding of disease3. Outline the ways in which genetic knowledge is impacting on drug design4. Demonstrate knowledge of the contribution of genetics to the study of behaviour and the brain.5. Research and integrate information from a range of sources in order to give a critical appraisal of a chosenspecialist area.6. Communicate knowledge of a particular area via an oral presentation.

Teaching and Learning MethodsLectures, tutorials

Assessment MethodsOral presentation, essay, examination.




Co-Requisites


Lectures 22Seminars








MB3050 Medical Genetics




001 Essay 15002 Critical Evaluation 15003 Examination (Final) 70 3

Period: Semester 2Occurence: ACoordinator: Blair GrubbMark Scheme: UG Pass for Credit


005 Essay 15006 Critical Evaluation 15007 Examination (Final) 70 3

Period: Semester 2Occurence: ECoordinator: Blair GrubbMark Scheme: UG Pass for Credit


Intended Learning OutcomesOn completion of this course students should be able to:• Explain and elucidate the genetic disorders underlying common, myopathic syndromes and the methods used toinvestigate possible modern therapies.• Understanding the general principles of neurodegenerative disease with particular emphasis on Alzheimer’sdisease.• Explain the clinical presentation of psychosis, in particular anxiety and depression, and the current theoriesregarding the molecular basis of these diseases.• Have a clear understanding of the consequences of brain injury/trauma and the short and long term regenerativeresponses of the brain.• Comprehend the basic mechanisms of pain transduction and processing and understand how chronicinflammatory diseases and nerve damage result in pain syndromes. Have a clear understanding of the mechanismof action of drugs that are used to treat these two conditions.• Understand the pathogenesis of epilepsy and discover how drug therapies work at the molecular level.• Understand the mechanisms of normal wound healing and develop an appreciation of why wounds sometimes failto heal.

Teaching and Learning MethodsLectures, tutorials, student presentations

Assessment Methods70% examination, 30% coursework (15% 2500 word essay, 15% critical evaluation of a scientific paper)









MB3057 Understanding Disease - An Integrated Approach



Pre-Requisites

Co-Requisites


MB3057 Understanding Disease - An Integrated Approach


module specification - university of leicester · 2015. 8. 3. · module specification no....

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