MONDAY

BIO I 1,2,5,7 Period 3-3-14Bell work: Pre-assessment of what you

know concerning DNA. Complete questions 1-10 on page 359.

Objective: I will demonstrate understanding of cell division through test and lab.

HOMEWORK: Review online activities for extra help.

Monday, 3-3-141. Bell work…10 min2. Chapter 11 test…15 min3. Finish Blood Typing Lab…25 min.4. Ticket out…5 min.

HOMEWORK: Read & Notes for 12.2. Be prepared to discuss 12.1 & 12.2 on Tuesday.Objective: I will demonstrate understanding of cell division

through test and lab.

Ticket out 3-3-14

Ticket out: Put computers away in correct slot and plug in.

HOMEWORK: Read & Notes for 12.2. Be prepared to discuss 12.1 & 12.2 on Tuesday.

TUESDAY

BIO I 1,2,5,7 Period 3-4-14Bell work: View the History on page

349. Read each year and determine which you find the most exciting. BE prepared to share.

Objective: I will demonstrate

understanding of historic discoveries concerning DNA through report.

HOMEWORK: Read & notes for 12.3.

Tuesday, 3-4-141. Bell work…8 min2. Group Reports…10 min3. Share Group Notes…10 min4. PP & Notes 12.1 & 12.2…20 min5. Ticket out…5 min.

HOMEWORK: Read & notes for 12.3.Objective: I will demonstrate

understanding of historic discoveries concerning DNA through report.

Notes 12.1 & 12.2

Early DNA Discoveries

Griffith 1928 & Avery 1944:

DNA (not RNA) is transforming agent.

Hershey-Chase 1953:

DNA (not protein) is the genetic material.

Gierer & Schramm 1956/Fraenkel-Conrat & Singer 1957:

RNA (not protein) is genetic material of some viruses, but no known prokaryotes or eukaryotes use RNA as their genetic material.

Alfred HersheyNobel Prize in Physiology or Medicine1969 8

Structure of DNA

James D. Watson/Francis H. Crick 1953 proposed the Double Helix Model based on two sources of information:

1. Base composition studies of Erwin Chargaff

• indicated double-stranded DNA consists of ~50% purines (A,G) and ~50% pyrimidines (T, C)

• amount of A = amount of T and amount of G = amount of C(Chargraff’s rules)

• %GC content varies from organism to organism

Examples: %A %T %G%C %GC

Homo sapiens 31.0 31.5 19.1 18.4 37.5Zea mays 25.6 25.3 24.5 24.6 49.1Drosophila 27.3 27.6 22.5 22.5 45.0Aythya americana 25.8 25.8 24.2 24.2 48.4

9

Ticket out 3-4-14

Ticket out: Who do you think made the most important DNA discovery?

• HOMEWORK: Read & notes for 12.3.

WEDNESDAY

BIO I 1,2,5,7 Period 3-5-14Bell work: Read “Components of

DNA page 344-345 and draw a “Nucleotide as seen on page 345. Objective: I will understand DNA structure through discussion and activity.

HOMEWORK: None

Wednesday, 3-5-14

1. Bell work…10 min2. Video preview of DNA…5 min3. Discussion & Notes 12.3…10 min4. DNA modeling…10 min5. Ticket out…5 min.

HOMEWORK: NoneObjective: I will understand DNA

structure through discussion and activity.

Ticket out 3-5-14Ticket out: Put model in

bagging and save for tomorrow.

• HOMEWORK: None

THURSDAY

BIO I 1,2,5,7 Period 3-6-14Bell work: View figure 12-10 as seen on

page 353. Explain in your own words the difference between replication of prokaryotic DNA and eukaryotic DNA.

Objective: I will demonstrate understanding of DNA and DNA replication through discussion and activity.

HOMEWORK: Review Ch. 12 for quiz on Monday.

Thursday, Bell work 3-6-14

1. Bell work…5 min2. Online 12.3 & notes…10 min.3. DNA modeling…20 min.4. Review for quiz…15 min5. Ticket out…5 min. HOMEWORK: Review Ch. 12 for quiz on

Monday.

1. Objective: I will demonstrate understanding of DNA and DNA replication through discussion and activity.

Notes 12.3

DNA polymerase is an enzyme that joins individual nucleotides to produce a new strand of DNA.

Replication in most prokaryotic cells starts from a single point and proceeds in two directions until the entire chromosome is copied.

In eukaryotic cells, replication may begin at dozens or even hundreds of places on the DNA molecule, proceeding in both directions until each chromosome is completely copied.

DNA Base Pairs

ACCTTGC GTACCTTGGAACG CATGGA

DNA Replication (using the above original strand)

A – TC-G C-GC-G C-GT-A T-AT-A T-AG-C G-CC-G C-G

DNA Base Pairs & Replication

Ticket out Bell work 3-6-14

Ticket out: Analyze

HOMEWORK: Review ch 12 for quiz on Monday