monthly healthcare review january 2017 - bioenterprise · amblyotech 24-jan-2017 marietta, ga angel...

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Monthly Healthcare Review January 2017 Company Name Last Financing Date HQ Location Description Last Financing Size (Millions) Lead Manager Jounce Therapeutics (JNCE) 27-Jan-2017 Cambridge, MA Developer of cancer immunotherapies designed to match the right therapy to the right patients enabling the immune system to attack tumors and provide long-lasting benefits to patients. 104.00 Cowen and Company, J.P. Morgan Securities ObsEva (OBSV) 26-Jan-2017 Geneva, Switzerland Developer of innovative drugs for women's reproductive health and pregnancy. 96.75 Credit Suisse Securities, Jefferies, Leerink Partners AnaptysBio (ANAB) 26-Jan-2017 San Diego, CA Developer of therapeutic antibodies for inflammation and immuno-oncology designed to provide first- in-class antibody product candidates. The company's therapeutic antibodies generates somatic hyper- mutation for antibody discovery and protein optimization which replicates, in vitro, the natural process of antibody generation, enabling medical experts to focus on unmet medical needs in inflammation. 75.00 BMO Capital Markets, Credit Suisse Securities, Stifel Nicolaus & Company Varex Imaging (VREX) 20-Jan-2017 Salt Lake City, UT Developer of medical X-ray tubes and image processing products designed to harness the power of X- ray energy to pioneer advances in any application. Undisclosed J.P. Morgan Securities, Wachtell, Lipton, Rosen & Katz Bioverativ (BIVV) 12-Jan-2017 Cambridge, MA The company engages in the research, development and treatment of hemophilia. Undisclosed Goldman, Sachs & Co., Guggenheim Securities AcouSort (ACOU) 09-Jan-2017 Lund, Sweden Developer of microchip technology designed for medical analysis and sorting of cells. The company's biomedical research and microchip technology applications in extracellular vesicles, bacteriological and cell-based research enables its clients to develop point-of-care instruments performing the same assays but without the need for access to a laboratory. 1.23 Undisclosed The following table includes the medical devices, biotechnology, pharmaceuticals, and healthcare IPO pricings, filings and withdrawals announced over the previous month. IPOs Compiled by: Sumerjit Sandhu Source: Pitchbook 1

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Page 1: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company NameLast Financing

DateHQ Location Description

Last

Financing

Size

(Millions)

Lead Manager

Jounce Therapeutics

(JNCE) 27-Jan-2017 Cambridge, MA

Developer of cancer immunotherapies designed to match the right therapy to the right patients

enabling the immune system to attack tumors and provide long-lasting benefits to patients. 104.00

Cowen and Company,

J.P. Morgan Securities

ObsEva (OBSV) 26-Jan-2017

Geneva,

Switzerland Developer of innovative drugs for women's reproductive health and pregnancy. 96.75

Credit Suisse

Securities, Jefferies,

Leerink Partners

AnaptysBio (ANAB) 26-Jan-2017 San Diego, CA

Developer of therapeutic antibodies for inflammation and immuno-oncology designed to provide first-

in-class antibody product candidates. The company's therapeutic antibodies generates somatic hyper-

mutation for antibody discovery and protein optimization which replicates, in vitro, the natural process

of antibody generation, enabling medical experts to focus on unmet medical needs in inflammation. 75.00

BMO Capital Markets,

Credit Suisse

Securities, Stifel

Nicolaus & Company

Varex Imaging (VREX) 20-Jan-2017

Salt Lake City,

UT

Developer of medical X-ray tubes and image processing products designed to harness the power of X-

ray energy to pioneer advances in any application. Undisclosed

J.P. Morgan Securities,

Wachtell, Lipton,

Rosen & Katz

Bioverativ (BIVV) 12-Jan-2017 Cambridge, MA The company engages in the research, development and treatment of hemophilia. Undisclosed

Goldman, Sachs &

Co., Guggenheim

Securities

AcouSort (ACOU) 09-Jan-2017 Lund, Sweden

Developer of microchip technology designed for medical analysis and sorting of cells. The company's

biomedical research and microchip technology applications in extracellular vesicles, bacteriological and

cell-based research enables its clients to develop point-of-care instruments performing the same assays

but without the need for access to a laboratory. 1.23 Undisclosed

The following table includes the medical devices, biotechnology, pharmaceuticals, and healthcare IPO pricings, filings and withdrawals announced over the previous month.

IPOs

Compiled by: Sumerjit Sandhu

Source: Pitchbook 1

Page 2: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

TC Biopharm 31-Jan-2017

Edinburgh, United

Kingdom Early Stage VC

Developer of an autologous anti-cancer immuno-therapy that involves expansion of

naturally occurring, cancer-killing T-cells over several weeks, formulating a

treatment for a wide-variety of different tumor types. 8.02

Scottish Enterprise,

Nipro

Netgain Hosting 31-Jan-2017 St. Cloud, MN

PE Growth/

Expansion

Provider of cloud management services and technology intended to simplify the

healthcare computing environment. The company's services provide a complete

end-point management allowing healthcare professionals to focus on patient care. 25.00 Bluff Point Associates

Kineta 31-Jan-2017 Seattle, WA Later Stage VC Developer of novel therapeutics. 1.75 Undisclosed Investors

Focal Point

Pharmaceuticals 31-Jan-2017 Memphis, TN Early Stage VC Developer of products designed to treat ocular diseases. 0.08 Undisclosed Investors

CryoCapCell 31-Jan-2017 Paris, France Seed Round

Developer and manufacturer of new products designed for sample preparation in

the field of electron microscopy. The company's CryoCapsule uses high-pressure

vitrification (or cryogenisation), a unique process which prevents the alteration of

biological structures, initially for electron-microscopy in the field of cancer research. 1.59 Seventure Partners

Chondrial Therapeutics 31-Jan-2017 Bala Cynwyd, PA Early Stage VC

Developer of biotechnology drugs designed to deliver the frataxin protein to the

mitochondria, helping patients who, due to a genetic abnormality, are unable to

produce this essential protein. 22.60 Deerfield Management

Cerus Endovascular 31-Jan-2017

Oxford, United

Kingdom Later Stage VC

Developer of proprietary interventional neuroradiology devices and delivery

systems designed for the treatment of neurovascular diseases, particularly

intracranial aneurysms. 2.39 Undisclosed Investors

Valeris Medical 30-Jan-2017 Marietta, GA Angel Manufacturer of orthopedic implants and delivery systems. 1.52 Undisclosed Investors

SafePath Medical 30-Jan-2017 Methuen, MA Angel Developer of medical devices for clinicians. 0.78 Undisclosed Investors

The Electrospinning

Company 27-Jan-2017

Didcot, United

Kingdom Later Stage VC

Manufacturer of electrospun biomaterials designed to help the body repair and

regenerate its own tissues. The company's electrospun biomaterials are used in

different applications in cell-based therapies, drug discovery and regenerative

medicine. 0.80

Rainbow Seedfund,

Undisclosed Investors

TELA Bio 27-Jan-2017 Malvern, PA Early Stage VC

Developer of soft tissue reconstruction products designed for use in hernia repair

and abdominal wall reconstruction. 7.39 Undisclosed Investors

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Compiled by: Sumerjit Sandhu

Source: Pitchbook 2

Page 3: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

CycloSam Therapeutics 27-Jan-2017 Angleton, TX Angel

Developer of a bone-seeking agent that allows delivery of high amounts of

radioactivity to bone and bone tumors while reducing bone marrow suppression,

enabling treatment of osteosarcoma and relief of pain from bone metastases as well

as reduced myelotoxicity for patients. 0.20 Undisclosed Investors

Biscayne

Neurotherapeutics 27-Jan-2017 Miami, FL Early Stage VC

Developer of Antiepileptic Agent BIS-001 created for serious central nervous

system disorders, such as refractory epilepsy. 3.00

Quark Venture and

GF Securities

Airing 27-Jan-2017 Burlington, Canada Angel Maker of a micro-CPAP device that relaxes people suffering from sleep apnea. 1.90 Undisclosed Investors

TAO 26-Jan-2017 Saint Petersburg, FL Angel

Provider of online mental health treatment services that delivers therapy via college

and university counseling centers, employee assistance programs, outpatient and

inpatient medical and mental health centers, and private practitioners. 1.56

FAN Fund, New

World Angels

SynAgile 26-Jan-2017 Wilson, WY Angel

Developer of an infusion therapy designed to enable patients to achieve stable

plasma L-DOPA concentrations and to provide convenient, noninvasive,

continuous dopaminergic stimulation. 4.68 Undisclosed Investors

Neograft Technologies 26-Jan-2017 Taunton, MA Later Stage VC

Developer of a cardiac device designed to improve vein performance in coronary

artery bypass. The company's cardiac device creates a support layer around the vein

using a novel process called electrospinning allowing nutrients and new cells to

migrate into and through the support layer without deforming its natural shape. 5.00 Undisclosed Investors

Medrobotics 26-Jan-2017 Raynham, MA Later Stage VC

Developer of medical robotics, including the patented Flex Robotic System,

designed to provide more patients with access to minimally invasive surgery. The

company's robot-assisted surgical platform offers flexible instruments that can be

deployed to perform procedures in a way that is not possible with line-of-sight

approaches. 20.00 Undisclosed Investors

KromaTid 26-Jan-2017 Fort Collins, CO Later Stage VC

Provider of products and services intended for mutation detection and disease

diagnosis of genetic diseases, including cancers and developmental disorders. 0.62 Undisclosed Investors

INRange Systems 26-Jan-2017 Altoona, PA Later Stage VC

Developer of EMMA, a telehealth medical device for documented and professional

medication administration to outpatients. 0.88 Undisclosed Investors

Cellestia Biotech 26-Jan-2017 Basel, Swaziland Seed Round

Developer of anti-cancer drugs focused on the treatment of patients with NOTCH-

dependent leukemia, lymphoma and solid tumors. 7.93

PPF Group,

Undisclosed Investors

Compiled by: Sumerjit Sandhu

Source: Pitchbook 3

Page 4: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Caelus Health 26-Jan-2017

Amsterdam,

Netherlands Early Stage VC

Developer of microbiome therapeutics created for the reduction of insulin

resistance and prevention of Type 2 diabetes in people. 2.65

Johnson & Johnson

Innovation

Bigfoot Biomedical 26-Jan-2017 Milpitas, CA Angel

Developer of a diabetes management system for people with insulin-dependent

diabetes and blood sugar control, enabling patients to improve their lives through

the application of smart technology. Undisclosed

Quadrant Capital

Advisors

AxioMed 26-Jan-2017 Malden, MA

PE Growth/

Expansion

Developer of spinal function products intended to address the unmet needs of

degenerative disc disease patients. 1.02 Undisclosed Investors

Allinaire Therapeutics 26-Jan-2017 Shaker Heights, OH Seed Round

Developer of therapeutics for lung diseases, like chronic obstructive pulmonary

disease. Undisclosed

BioCrossroads,

BioMotiv, Innovate

Indiana Fund

Well Beyond Care 25-Jan-2017 Austin, TX Seed Round

Developer of an online caregiving matching application created to connect people

who need care for elderly family members with caregivers. 0.15

Central Texas Angel

Network, Andrews

Kurth, Capital Factory

Thermedical 25-Jan-2017 Waltham, MA Later Stage VC

Developer of thermal ablation therapy designed to treat cancer and cardiac

arrhythmias. 6.50 Undisclosed Investors

Silverlon 25-Jan-2017 Geneva, IL

PE Growth/

Expansion

Manufacturer and distributor of innovative wound care products designed to be

extensively used for management of burn and blast injuries. The company's

Silverlon brand of dressings are uniquely designed with a silver-plated nylon matrix,

enabling the utilization of powerful antimicrobial properties of silver ions in the

dressing without staining the skin and without increasing bio-burden. Undisclosed Shore Capital Partners

Kensci 25-Jan-2017 Seattle, WA Early Stage VC

Provider of a risk management platform that uses machine learning and predictive

analytics to predict illness, improve care and optimize cost across patient

populations and individuals. 8.50

Ignition Venture

Partners

Doctolib 25-Jan-2017 Paris, France Later Stage VC

Developer of an application platform designed for patients to choose their doctor,

make an appointment and monitor their health. 27.61 Bpifrance

WellTrackONE 24-Jan-2017

Hilton Head Island,

SC Early Stage VC

Provider of a Medicare-approved patient assessment program designed to give

physicians and organizations a baseline report detailing modifiable risk factors,

preventative goals and measurable data. 1.99

BioAdvance,

Undisclosed Investors

Redox 24-Jan-2017 Madison, WI Early Stage VC Provider of an information technology platform for healthcare systems. 9.00 RRE Ventures

Compiled by: Sumerjit Sandhu

Source: Pitchbook 4

Page 5: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

First Light Biosciences 24-Jan-2017 Bedford, MA Early Stage VC

Developer of diagnostic devices for DNA-based detection of infections, using

digital imaging to detect and count fluorescent targets without using magnification. 1.79

Keiretsu Capital,

Keiretsu Forum,

Undisclosed Investors

Connect

Biopharmaceuticals 24-Jan-2017 Taicang, China Early Stage VC

Developer of novel immune modulators for the treatment of autoimmune diseases

and cancer created to identify therapeutic antibody drug candidates. 20.00 Qiming Venture

CardioSecur 24-Jan-2017 Frankfurt, Germany Later Stage VC

Developer of a smartphone-based personalized ECG application created to offer

cardiac monitoring services. 5.31 KPN Ventures

Amblyotech 24-Jan-2017 Marietta, GA Angel

Developer of an electronic media application designed to treat amblyopia and other

ocular diseases. 0.20 Undisclosed Investors

Aldevron 24-Jan-2017 Fargo, ND

PE Growth/

Expansion

Developer of biological products, such as plasmid DNA, proteins and antibodies,

that are used extensively in the fields of gene therapy and gene editing, enabling its

clients to manufacture novel treatments for a wide range of indications, including

cancer, infectious disease, pediatric disorders and rare diseases. Undisclosed

TA Associates

Management

Smart Med Reminder 23-Jan-2017 West Lafayette, IN Later Stage VC

Provider of a medication reminder system in the form of a medicine bottle cap that

tracks and reminds users to take medicines on time. 1.30 Undisclosed Investors

Micro C Imaging 23-Jan-2017 Savannah, GA Angel

Developer of a hand-held, wireless X-ray and digital imaging device that converts

radiation to real time static and dynamic fluoroscopic images, enabling surgeons,

doctors and healthcare providers to bring the X-ray source to the target to produce

more resolute images. 0.65 Undisclosed Investors

HabitAware 23-Jan-2017 Minneapolis, MN Angel

Developer of a subconscious-behavior tracker wearable device designed to manage

compulsive behavior. 0.51 Undisclosed Investors

Focal Therapeutics 23-Jan-2017 Aliso Viejo, CA Later Stage VC

Developer and manufacturer of novel tissue-marking devices for use in surgery

designed to mark the surgical site of tissue removal in 3D. 0.05 Undisclosed Investors

Atlas Genetics 23-Jan-2017

Trowbridge, United

Kingdom Later Stage VC

Developer of a novel molecular diagnostic system used for the ultra-rapid diagnosis

of a broad range of infectious diseases, such as chlamydia, gonorrhoea, meningitis

and MRSA, enabling physicians to get accurate diagnostic reports. 35.00

Novartis Venture

Funds, Consort

Medical, Johnson &

Johnson Innovation -

JJDC

Compiled by: Sumerjit Sandhu

Source: Pitchbook 5

Page 6: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Finch Therapeutics 21-Jan-2017 Somerville, MA Angel

Developer of a microbiome discovery platform that mines molecular data collected

from human interventional studies and uses proprietary machine learning

techniques, enabling care providers and patients to treat diseases and infections

faster. 3.73 Undisclosed Investors

Thermal Gradient 20-Jan-2017 Richmond, VA Later Stage VC

Developer of diagnostics devices that use proprietary thermal cycling, nucleic acid

extraction and purification technologies to detect and measure patient blood

samples, particularly in low resource settings, providing existing markets, as well as

new markets that cannot be addressed with existing technologies, with access to

faster and less expensive DNA testing products. 0.61 Undisclosed Investors

REACH Health 20-Jan-2017 Alpharetta, GA Later Stage VC

Provider of a telemedicine platform that offers physicians evaluation software to

assess and provide treatment options using video and patient medical data. 1.80 Undisclosed Investors

Tueo Health 19-Jan-2017 Redwood City, CA Seed Round

Developer of an asthma monitoring system using a contactless sensor, enabling

patients and their families to measure treatment progress and outcomes. 0.40 Undisclosed Investors

Rhythm Pharmaceuticals 19-Jan-2017 Boston, MA Later Stage VC

Developer of small-peptide therapeutics for the treatment of gastrointestinal

functional disorders, obesity and diabetes. 20.48 Undisclosed Investors

OCTIMET 19-Jan-2017 Beerse, Belgium Early Stage VC Developer of discovery stage molecules used for the treatment of cancer cells. 12.00

Droia, Fund+, Omnes

Capital

Maverick Therapeutics 19-Jan-2017 Brisbane, CA Early Stage VC

Developer of a novel biologics platform designed to be inactive upon

administration but fully active in the tumor micro-environment, improving the

utility of T-cell redirection therapy for the treatment of cancer. 56.00

MPM Capital and

Takeda Pharmaceutical

iHear Medical 19-Jan-2017 San Leandro, CA Later Stage VC

Developer of an online hearing solution platform that enables people with hearing

loss to customize advanced hearing aids settings themselves at home. 4.10

Ameritas Life

Insurance

Cristal Therapeutics 19-Jan-2017

Maastricht,

Netherlands Later Stage VC

Developer of therapies employing nanoparticle technology designed against cancer

and chronic inflammatory disorders. 13.59

Aglaia BioMedical

Ventures, DROIA

BiVictrix Therapeutics 19-Jan-2017

Alderley Edge, United

Kingdom Seed Round

Developer of therapies for hematological cancers that reduce off-target side effects

on healthy tissues, enabling patients to use their drugs without facing any side

effects. 0.53

Alderley Park Ventures

of Biocity, Finance

Wales, Undisclosed

Investors

Compiled by: Sumerjit Sandhu

Source: Pitchbook 6

Page 7: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Adarza BioSystems 19-Jan-2017 West Henrietta, NY Later Stage VC

Developer of a diagnostic platform capable of simultaneous detection of hundreds

of analytes in a single drop of fluid, enabling highly multiplexed protein detection

with high sensitivity and specificity. 17.00

RiverVest Venture

Partners

Wenzel Spine 18-Jan-2017 Austin, TX Later Stage VC

Provider of the VarLift Interbody Fusion System designed for surgeons to shorten

spine fusion surgeries. 1.60 Undisclosed Investors

Weinberg Medical Physics 18-Jan-2017 Rockville, MD Later Stage VC

Developer of imaging systems and devices designed to detect breast cancer and

guide cancer surgery, providing diagnostic accuracy while reducing side effects, and

enhance scientists' ability to track stem cells. 1.31 Undisclosed Investor

Synthomics 18-Jan-2017 Menlo Park, CA Seed Round

Developer of an oligonucleotide synthesizer designed to improve the economics,

speed, customization and quality associated with DNA and RNA synthesis. Undisclosed TEEC Angel Fund

SynGen 18-Jan-2017 Sacramento, CA Later Stage VC

Developer of single use disposable cartridges to capture stem and progenitor cells

from peripheral and umbilical cord blood, bone marrow and adipose tissue. 2.50 Undisclosed Investors

SilverCloud (Healthcare

Technology) 18-Jan-2017 Dublin, Ireland Later Stage VC

Provider of an online health and e-therapy platform intended to improve behavioral

health and mental wellness. 8.10 B Capital Group

SapVax 18-Jan-2017 Cleveland, OH Angel

Developer of a suite of first-in-class therapeutic cancer vaccines based on a novel

peptide platform technology targeting a key antigen expressed in a broad range of

cancers and Epstein-Barr virus proteins strongly associated with nasopharyngeal

cancer, lymphoma and gastric cancer. 0.35 Undisclosed Investors

Ovid Therapeutics 18-Jan-2017 New York, NY Later Stage VC Developer of drugs for orphan diseases of the brain. 25.86 Undisclosed Investors

Liquid Genomics 18-Jan-2017 Torrance, CA Early Stage VC

Operator of a blood-based biomarker company focused on monitoring cancer

patients for chemotherapy response. 1.63 Undisclosed Investors

Renovion 17-Jan-2017 Chapel Hill, NC Angel

Developer of a therapy for patients who have received a bilateral lung transplant

and suffer from chronic inflammatory airway diseases. 1.87 Undisclosed Investors

Practo 17-Jan-2017 Bangalore, India Later Stage VC

Provider of an online service for scheduling appointments with doctors and storage

of healthcare records including X-rays, files, prescriptions and billing. 55.00 Tencent Holdings

Fibrocor Therapeutics 17-Jan-2017 Toronto, Canada Early Stage VC Developer of novel therapeutics for the treatment of fibrosis. 2.12 MaRS Innovation

Compiled by: Sumerjit Sandhu

Source: Pitchbook 7

Page 8: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Evelo Biosciences 17-Jan-2017 Cambridge, MA Early Stage VC

Developer of bacterial-based therapeutics to leverage the ability of specific strains

of bacteria, to potently activate the immune system against tumors and down-

regulate the immune system for the treatment of autoimmune and inflammatory

diseases. 45.50 Undisclosed Investors

CardioDx 17-Jan-2017 Redwood City, CA Later Stage VC

Developer of diagnostic tests designed to identify patients unlikely to have

obstructive CAD. 18.13 Undisclosed Investors

AMRA 17-Jan-2017 Linkoping, Sweden Later Stage VC

Developer of MR imaging that provides body composition analysis to quantify the

amounts of visceral fat, subcutaneous fat, liver fat deposits and muscles. 9.00

Pfizer Venture

Investments, Novo

Ambassador Software

Works 17-Jan-2017 Columbus, OH Early Stage VC

Provider of a SaaS-based platform that enables clinical personnel to pull real-time

patient information from the hospital's electronic medical records and use

predictive analytics to anticipate patient needs. 0.40

Rev1 Ventures, Ross

Youngs

Realist Pharma 16-Jan-2017 Toronto, Canada Early Stage VC

Developer of cell therapies and cancer vaccines intended to treat cancer through a

patient's own immune system. 0.05 Undisclosed Investor

Thetis Pharmaceuticals 13-Jan-2017 Fairfield, CT Early Stage VC

Developer of pharmaceutical drugs that uniquely targets both glycemic and lipid

control in diabetes patients. 4.11

Connecticut

Innovations,

Undisclosed Investors

POPS! Diabetes Care 13-Jan-2017

Oak Park Heights,

MN Angel Developer of glucose monitoring devices for diabetic patients. 1.23 Undisclosed Investors

Maui Imaging 13-Jan-2017 Sunnyvale, CA Later Stage VC Developer of ultrasonic imaging devices via a portable system. 0.66 Undisclosed Investors

Femasys 13-Jan-2017 Suwanee, GA Later Stage VC

Developer of a non-surgical female sterilization device and two commercially

available products for the diagnosis of infertility and cervical cancer. 44.00 Salem Partners

Virtual Possibilities 12-Jan-2017 Hamilton, Canada Angel

Developer of computer assisted medical devices for future-facing laparoscopic

surgeries. Undisclosed Undisclosed Investors

Signallamp Health 12-Jan-2017 Scranton, PA Angel

Provider of a technology infrastructure that delivers chronic care management

services to Medicare beneficiaries through a team of experienced registered nurses

who contact patients on a monthly basis. 0.14 Undisclosed Investors

Compiled by: Sumerjit Sandhu

Source: Pitchbook 8

Page 9: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

PathAI 12-Jan-2017 Boston, MA Early Stage VC

Developer of cancer diagnosis artificial intelligence technology that applies deep

learning techniques to massive aggregated sets of pathology data to build

algorithms to automatically detect and diagnose medical conditions for cancer

patients to receive faster, accurate and reproducible diagnosis. Undisclosed Pillar Venture Capital

OncoImmune 12-Jan-2017 Gaithersburg, MD Later Stage VC

Developer of novel immunotherapies for cancer, inflammation and autoimmune

diseases. 15.00 3E Bioventures Capital

Luxendo 12-Jan-2017 Heidelberg, Germany Early Stage VC

Developer of the light-sheet microscopes that combines optical sectioning with

multiple-view imaging to observe tissues and living organisms with clear resolution. 8.49

EMBL Ventures,

EMBL Enterprise

Management

Technology Transfer,

Life Science Partners

Clearwater Clinical 12-Jan-2017 Ottawa, Canada Later Stage VC

Developer and manufacturer of mobile medical devices for diagnosis of common

medical conditions. 6.00

Whitecap Venture

Partners

Verisma Systems 11-Jan-2017 Pueblo, CO

PE Growth/

Expansion

Provider of health information technology intended to provide release of

information services. 2.50 Undisclosed Investors

Unyq Design 11-Jan-2017 San Francisco, CA Early Stage VC

Manufacturer of custom prosthetic covers for amputees. The company offers

reimagining orthotics and prosthetics by 3D printing and handcrafting custom,

fashionable fairings and accessories that embellish and restore body symmetry. 4.28

Graph Ventures,

HealthTech Capital,

Undisclosed Investors

ToolBox Genomics 11-Jan-2017 San Francisco, CA Seed Round

Provider of gene-based food and lifestyle recommendations designed to build a

healthier life and reduce risk of chronic conditions. Undisclosed Undisclosed Investors

SemaThera 11-Jan-2017 Montreal, Canada Angel

Developer of protein inhibitors for the treatment of ocular diseases, such as

diabetic macular edema. 1.00 Undisclosed Investors

OtoNexus Medical

Technologies 11-Jan-2017 Seattle, WA Later Stage VC

Developer of medical devices for data physicians that uses air-coupled ultrasound

technology to assess middle ear infections. 7.85 Undisclosed Investors

IRX Therapeutics 11-Jan-2017 New York, NY Angel

Developer of therapies designed to activate a patient's immune system to defeat

cancer and related diseases. 13.24 Undisclosed Investors

EndoCellutions 11-Jan-2017 Marshfield, MA Angel

Developer of medical devices to collect stem cells and deliver tissues to damaged

areas. 0.60 Undisclosed Investors

Compiled by: Sumerjit Sandhu

Source: Pitchbook 9

Page 10: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

AcceleDent 11-Jan-2017 Bellaire, TX Later Stage VC

Developer, manufacturer and marketer of a device that applies pulsing forces in

combination with standard orthodontics to move teeth faster through accelerated

bone remodeling allowing patients to have a reduced treatment duration for

wearing braces. 5.00

S3 Ventures,

HealthpointCapital,

Piper Jaffray Merchant

Banking

Sera Prognostics 10-Jan-2017 Salt Lake City, UT Later Stage VC

Provider of diagnostic tests for early prediction of preterm birth, preeclampsia and

other pregnancy complications. 40.00

Laboratory

Corporation of

America

POC Medical Systems 10-Jan-2017 Livermore, CA Early Stage VC

Developer of a microfluidic platform for rapid, point-of-care serum screening that

uses antibodies to detect biomarkers using a novel and compact microfluidics

system containing a built-in reading mechanism. 20.40 BioVentures Investors

Piedmont Stone Center 10-Jan-2017 Winston-Salem, NC Angel

Provider of non-surgical treatment for kidney stones using extracorporal shock

wave lithotripsy. 0.57 Undisclosed Investors

Medinfi Healthcare 10-Jan-2017 Bangalore, India Angel Provider of an online platform to browse and find doctors and hospitals. 0.10

Vinod Martin, Evan

Lim, Kanchan

Ghoshal

Footbeat 10-Jan-2017 Grand Junction, CO Angel

Developer of a device that provides cyclic thrusting pressure to the foot capillary

bed at the plantar venous plexus. 7.60 Undisclosed Investors

Bioscape Digital 10-Jan-2017 Atlanta, GA Angel

Provider of a platform that helps hospitals improve patient engagement and gather

feedback. 0.53 Undisclosed Investors

Aledade 10-Jan-2017 Bethesda, MD Early Stage VC

Provider of a technology platform for physicians to help deliver care to their

patients while reducing overall costs. 20.00 Biomatics Capital

Vaxess Technologies 09-Jan-2017 Boston, MA Later Stage VC

Developer of proprietary technologies based on a silk biopolymer platform for

encapsulating and stabilizing biological compounds. 0.86 Undisclosed Investors

ReThink Medical 09-Jan-2017 San Francisco, CA Angel

Developer of a sensor-based wearable device that monitors heartbeat rate and

detects heart related disorders, preventing heart attacks and similar fatal health

conditions. 3.22 Undisclosed Investors

PeraHealth 09-Jan-2017 Charlotte, NC

PE Growth/

Expansion Developer of a technology platform for predicting patient risk. 14.00 Mainsail Partners

Novome Biotechnologies 09-Jan-2017 Daly City, CA Angel

Provider of a drug discovery platform that utilizes engineered gut bacteria for

treating disease through the development of tools for controlling their abundance

in patients. 0.54 Undisclosed Investors

Compiled by: Sumerjit Sandhu

Source: Pitchbook 10

Page 11: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

NeuroPace 09-Jan-2017 Mountain View, CA Later Stage VC

Developer of a responsive neurostimulator system for the treatment of medically

refractory partial epilepsy. 50.00

KCK, Undisclosed

Investors

Macrophage Pharma 09-Jan-2017

Berkhamsted, United

Kingdom Early Stage VC

Developer of novel therapies to enhance anti-tumour immune responses to boost

up the body's natural immune system to fight cancer. 11.10

Cancer Research

Technology

LifeTime 09-Jan-2017 Hamburg, Germany Early Stage VC

Provider of a digital health application that enables users to store and manage their

health data digitally and import reports or X-rays directly after medical

consultations. 1.06

Thieme, High-Tech

Gründerfonds,

Fraunhofer-Society

Ivantis 09-Jan-2017 Irvine, CA Later Stage VC

Developer of a minimally invasive microsurgical procedure for the treatement of

glaucoma and other eye diseases that reduces eye pressure by re-establishing the

patient's natural outflow pathway. 25.00

RA Capital

Management

Eternygen 09-Jan-2017 Berlin, Germany Early Stage VC

Developer of a therapy of small molecule inhibitors for dietary-related metabolic

diseases by addressing sodium coupled citrate transporter NaCT, which is a key

regulator of lipid metabolism involved in the pathogenesis of fatty liver, diabetes

and obesity. 8.49 Epidarex Capital

d2i (Healthcare Analytics) 09-Jan-2017 Parsippany, NJ Angel

Developer of a platform that combines on-premise, on-demand, web-based, SaaS

dashboards and reports and analytic support services for emergency departments,

as well as other clinical departments. Undisclosed

Howard Goldstein,

John Martinson, Beta

Operators Fund

Corbin Therapeutics 09-Jan-2017 Montreal, Canada Seed Round Provider of a drug discovery platform to treat various inflammation-based diseases. 0.76 Undisclosed Investors

Adynxx 09-Jan-2017 San Francisco, CA Later Stage VC

Developer of a technology platform addressing body pain at its molecular roots.

The company develops a technology that prevents the development of pain

following surgery or trauma and resolving established chronic pain syndromes. 16.00 TPG Biotech

Pursuant Health 08-Jan-2017 Atlanta, GA Later Stage VC

Provider of self-service consumer healthcare utilizing technology to develop and

deploy interactive healthcare platforms and kiosks. 12.80 Undisclosed Investors

Virtual Health Partners 06-Jan-2017 New York, NY Angel

Provider of a platform that enables patients to virtually receive ancillary care

treatments such as nutrition, fitness and behavior modification and helps improve

post-care patient compliance. 1.62 Undisclosed Investors

Vir Biotechnology 06-Jan-2017 San Francisco, CA Early Stage VC

Developer of a cure for infectious diseases through immune programming to

manipulate pathogen-host interactions. 150.00

ARCH Venture

Partners, Bill &

Melinda Gates

Foundation

Compiled by: Sumerjit Sandhu

Source: Pitchbook 11

Page 12: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Titan Spine 06-Jan-2017 Mequon, WI

PE Growth/

Expansion

Designer and manufacturer of titanium interbody cage devices utilized in the spinal-

fusion surgical process. 9.17

Southlake Equity

Group, Undisclosed

Investors

ThinkIT 06-Jan-2017 Kampala, Uganda Angel

Developer of a mobile application that can be attached to a matiscope device for

detecting and diagnosing malaria. 0.10 Undisclosed Investors

Tesser Health 06-Jan-2017 Miami, FL Seed Round

Provider of a suite of software tools created to increase patient education and

improve health outcomes through chronic condition management, smart triage

tools and medication adherence. 0.47 Cofounders Capital

SiteOne Therapeutics 06-Jan-2017 Bozeman, MT Later Stage VC

Developer of a treatment for neuropathic pain through novel pain therapeutics

without the limitations of existing drugs, such as opioids. 15.00 Amgen

Neurelis 06-Jan-2017 Encinitas, CA Later Stage VC

Developer of technology-enhanced pharmaceutical products for epilepsy and

central nervous system disorders. 20.00

HBM Healthcare

Investments

NeoTract 06-Jan-2017 Pleasanton, CA Later Stage VC

Developer of surgical devices for the treatment of urological and gynecological

disorders. 12.82 Undisclosed Investors

Kinsa 06-Jan-2017 San Francisco, CA Early Stage VC

Developer of a smartphone-connected thermometer that provides a real-time map

and information on user's health temperature, symptoms and medication on a

connected smartphone. 14.07 Undisclosed Investors

Inbox Health 06-Jan-2017 Bridgeport, CT Early Stage VC

Developer of a web-based platform for healthcare providers to send invoices,

process payments, and track patient interaction with invoices related to medical

services they provide. 3.01 Undisclosed Investors

Healthie 06-Jan-2017 Lewes, DE Seed Round Provider of a web and mobile platform for dietitians and nutritionists. 0.99 Dorm Room Fund

Diagnotes 06-Jan-2017 Indianapolis, IN Later Stage VC

Provider of healthcare management services. The company provides a mobile and

web-based software system to improve physician communication with their

patients, care teams and office staff. 1.00 Undisclosed Investors

Cavion 06-Jan-2017 Charlottesville, VA Later Stage VC Developer of oncology drugs for the treatment of cancer. 26.10

Lilly Ventures,

Novartis Venture

Funds

Avalon Healthcare

Solutions 06-Jan-2017 Tampa, FL Early Stage VC

Provider of laboratory benefits management services by reducing unnecessary

utilization, optimizing network and increasing scores for payers through quality

improvement. Undisclosed

Echo Health Ventures,

BlueCross BlueShield

of South Carolina,

Francisco Partners

Compiled by: Sumerjit Sandhu

Source: Pitchbook 12

Page 13: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Aileron Therapeutics 06-Jan-2017 Cambridge, MA Later Stage VC

Developer of novel therapeutics for the treatment of cancer using proprietary cell

permeable peptide technology. 30.11

KCK Group, Excel

Venture Management,

Lilly Ventures,

Novartis Venture

Funds

Therachon 05-Jan-2017 Biot, France Early Stage VC

Developer of healthcare therapies for achondroplasia (short-limbed dwarfism) and

its associated complications. 40.00 OrbiMed

The Pill Club 05-Jan-2017 Redwood City, CA Angel Developer of a mobile application software for medicine delivery. 3.18 Undisclosed Investors

Synaptive 05-Jan-2017 Toronto, Canada

PE Growth/

Expansion

Provider of neurosurgical technological products and services. The company

provides advanced tools and information for neurosurgeons, radiologists, surgeons

and hospitals to focus on patient outcomes. 5.54

General Atlantic,

Undisclosed Investors

Satsuma Pharmaceuticals 05-Jan-2017 San Francisco, CA Early Stage VC Developer of nasal migraine drugs. 12.00

RA Capital

Management, TPG

Biotech

PaySpan 05-Jan-2017 Jacksonville, FL

PE Growth/

Expansion Provider of healthcare reimbursement and payment automation services. Undisclosed Primus Capital Funds

NeRRe Therapeutics 05-Jan-2017

Stevenage, United

Kingdom Early Stage VC

Developer of clinical and pre-clinical neurokinin receptor antagonists for the

treatment of common, chronic and debilitating conditions caused by neuronal

hypersensitivity. 28.37

Fountain Healthcare

Partners, Forbion

Capital Partners,

OrbiMed

Neon Therapeutics 05-Jan-2017 Cambridge, MA Early Stage VC

Developer of neoantigen-based therapeutic vaccines and T-cell therapies to treat

cancer. 70.00

Partner Fund

Management

Molecular Stethoscope 05-Jan-2017 San Diego, CA Seed Round

Developer of proprietary technology that analyzes circulating cell-free RNA in a

blood sample to monitor organ damage and provide early detection of hard-to-

detect diseases. 8.20

Data Collective, Pfizer,

Index Ventures

Microbion 05-Jan-2017 Bozeman, MT Later Stage VC

Developer of antimicrobial therapeutics to prevent microbial biofilms from

forming on medical devices implanted in the body. 25.00

Quark Ventures, GF

Securities

Jupiter Orphan

Therapeutics 05-Jan-2017 Jupiter, FL Early Stage VC

Developer of therapies for treatment of rare diseases linked to single gene

deficiencies. 2.50

Tarnagulla Ventures,

Undisclosed Investors

Compiled by: Sumerjit Sandhu

Source: Pitchbook 13

Page 14: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

ivWatch 05-Jan-2017 Hampton, VA Angel

Provider of an intravenous infiltration detector device designed to monitor the

status of a patient's IV therapy to aid in the early detection of peripheral IV

infiltrations. 9.29 Undisclosed Investors

Intuity Medical 05-Jan-2017 Sunnyvale, CA Later Stage VC

Developer of a blood glucose meter and multi-test cartridge that provides

automatic testing with lancing, blood collection and analysis without the need for

separate strips and lancets. 55.00

PTV Healthcare

Capital, KCK Group

HepaRegenix 05-Jan-2017 Germany Early Stage VC

Developer of drugs for treating acute and chronic liver diseases that effectively

restore the regenerative capacity of hepatocytes. 9.56

Boehringer Ingelheim

Venture Fund, Novo

Seeds

GeneCentric Diagnostics 05-Jan-2017 Durham, NC Early Stage VC

Developer of molecular diagnostic tests for oncologists and patients that identifies

patients who would benefit from drugs that inhibit tumor growth. 6.11 Undisclosed Investors

CiVi Biopharma 05-Jan-2017 San Francisco, CA Early Stage VC Developer of treatments and therapies against cardiometabolic diseases. 40.00 Tavistock Group

Blackthorn Therapeutics 05-Jan-2017

South San Francisco,

CA Early Stage VC Developer of therapeutic drugs for neurological disorders. 54.00

ARCH Venture

Partners

Avidity Biosciences 05-Jan-2017 San Diego, CA Early Stage VC Developer of an antibody cancer therapy utilizing nanoparticle technology. 16.00 Takeda Ventures

Arcadia Healthcare

Solutions 05-Jan-2017 Burlington, MA

PE Growth/

Expansion

Operator of an electronic health record data aggregation and analytics technology

company. The company offers data integration from over 30 EHR vendors,

enriching it with claims and operational data, and using that data to drive

improvements in patient care quality, practice efficiency and financial performance. 30.00

GE Ventures, Merck

Global Health

Innovation, Morgan

Stanley, Peloton

Equity, Zaffre

Investments

Yostra Labs 04-Jan-2017 Bengaluru, India Early Stage VC

Manufacturer of medical devices that enables medical professionals to diagnose and

treat diabetic peripheral neuropathy and diabetic foot ulcers. Undisclosed

Marico Innovation

Foundation, Villgro

Innovation Marketing

Synthego 04-Jan-2017 Redwood City, CA Early Stage VC Developer of a precision tool to automate genome engineering research. 41.00 8VC

Pionyr

Immunotherapeutics 04-Jan-2017 San Francisco, CA Early Stage VC

Developer of drugs for immunotherapy to identify and target novel arms of the

immune response within the tumor micro environment. 8.00

SV Life Sciences

Advisers, OrbiMed

Compiled by: Sumerjit Sandhu

Source: Pitchbook 14

Page 15: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Medley Genomics 04-Jan-2017 Providence, RI Seed Round

Developer of advanced analytics to assess the complex genomic heterogeneity in

biological samples and support targeted therapies. 0.25

Slater Technology

Fund

Avizia 04-Jan-2017 Reston, VA Early Stage VC

Developer of a telehealth and remote conferencing software platform that allows

medical experts to reach out to their patients through telemedicine anywhere

without being physically present. It also provides workflow management software,

store-and-forward capabilities with electronic health record integration and a line of

peripherals, such as digital stethoscopes and examination cameras. 20.00 HealthQuest Capital

Artsavit 04-Jan-2017 Tel Aviv, Israel

Accelerator/

Incubator

Developer of a treatment for cancer that involves activating a controlled cell-killing

mechanism called an apoptosis. Undisclosed

Merck Ventures Israel

BioIncubator

AristaMD 04-Jan-2017 San Diego, CA Early Stage VC

Provider of an intelligence platform for clinicians to assist primary care providers in

offering expanded specialty care to reduce unnecessary referrals. Undisclosed

Philadelphia College of

Osteopathic Medicine

Transplant Biomedicals 03-Jan-2017 Barcelona, Spain Early Stage VC

Developer of novel medical strategies intended to improve organ, tissue and

cellular preservation to overall enhance patients' wellness. It is used in preservation

of the organs during transport from the donor hospital to the transplant center. 2.65

Caixa Capital Risc,

Kereon Partners

Solera (Health Network) 03-Jan-2017 Phoenix, AZ Early Stage VC

Provider of a technology-enabled health community integrator for chronic disease

prevention programs. 9.00

Sandbox Industries,

SJF Ventures

Labcyte 03-Jan-2017 Sunnyvale, CA Later Stage VC

Provider of an acoustic droplet ejection technology that focuses on ultrasonic

acoustic energy into a fluid sample to eject droplets of liquid from open wells. 5.00 Undisclosed Investor

Intact Vascular 03-Jan-2017 Wayne, PA Early Stage VC

Developer of products for minimally invasive peripheral vascular procedures. The

company offers a tack-it endovascular stapler system that is designed to optimize

peripheral balloon angioplasty results in the treatment of peripheral artery disease. 46.00

New Enterprise

Associates

Ascletis 03-Jan-2017 Hangzhou, China Early Stage VC

Developer of new treatments for cancer and infectious diseases, with both small

molecule and biologics approaches. 100.77 C-Bridge Capital

Ascentage Pharma 03-Jan-2017 Shanghai, China Later Stage VC

Developer of small-molecule targeted therapeutics for cancer, hepatitis B and age-

related diseases. 72.00

SDIC Innovation

Investment

Management

Orello Hearing

Technologies 01-Jan-2017 Surrey, Canada

Accelerator/

Incubator

Developer of a hearing aid designed to make hearing healthcare more accessible

and affordable for individuals who are hard of hearing. 0.05 The Next Canada

Compiled by: Sumerjit Sandhu

Source: Pitchbook 15

Page 16: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Lead Investor(s)

Private Equity Placements and Venture Capital Rounds

The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

AFTx 01-Jan-2017 Westminster, CO Angel Developer of diagnostic equipment and other medical devices. 0.41 Undisclosed Investors

Compiled by: Sumerjit Sandhu

Source: Pitchbook 16

Page 17: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Acquirer Target HQ Location Date DescriptionTransaction

Value (Millions)

CompuVision Sagewood Systems Santa Barbara, CA 31-Jan-2017

Provider of healthcare technology strategic planning, product selection and contracting,

disaster recovery or business continuity systems, clinical system integration and health

information, enabling healthcare providers to meet day to day IT management challenges. Undisclosed

3D Systems Nextdent

Soesterberg,

Netherlands 31-Jan-2017

Manufacturer of dental 3D printing materials specializing in photopolymer, thermoplastic,

polymer and monomer materials. Undisclosed

Grifols

Hologic (Blood

Screening Joint

Venture) San Diego, CA 31-Jan-2017

Developer of blood-screening products and services used to scan donated blood for

viruses, including HIV, Hepatitis C and B and Zika. 1,850.00

ChoiceSpine Exactech Spine Gainesville, FL 31-Jan-2017

Developer of innovative spinal and orthobiologics created to improve patient outcomes

and restore spine health. Undisclosed

PotNetwork Holdings Diamond CBD Fort Lauderdale, FL 31-Jan-2017

Manufacturer of hemp extract products that help in controlling epileptic seizures, reducing

pain and inflammation, and may also be an effective treatment for mental health disorders,

such as addiction and various forms of psychosis. Undisclosed

InTouch Health C30 Medical Ojai, CA 31-Jan-2017

Provider of physician-led telemedicine management and physician coverage services

intended to provide cost-effective remote physician services. Undisclosed

CRA International C1 Consulting Summit, NJ 31-Jan-2017

Provider of life sciences strategy consulting services designed to develop high tailored

commercialization strategies for rare disease, oncology, immunology, neuroscience and

specialty biopharma. Undisclosed

ESI Process Sunflower Medical

Bradford, United

Kingdom 30-Jan-2017 Manufacturer of healthcare equipment and furniture for hospitals and clinics. Undisclosed

Northlane Capital Partners

PAR Excellence

Systems Cincinnati, OH 30-Jan-2017

Developer of medical supply chain management software designed to simplify the

caregivers' day-to-day inventory management tasks and allow them to focus on their core

objective of patient care. Undisclosed

DCC Healthcare Medisource Ireland Wicklow, Ireland 26-Jan-2017

Supplier of exempt medicinal products, enabling large and small biotech companies to

provide life cycle management of their product portfolio, from pre-launch medicines right

through to discontinuation strategies for mature products. 33.98

Kuros Xpand Biotechnology

Bilthoven,

Netherlands 25-Jan-2017 Developer of technologies for bone repair. Undisclosed

Sumitomo Dainippon

Pharma

Tolero

Pharmaceuticals Lehi, UT 25-Jan-2017

Developer of therapeutics for the treatment of cancer and other diseases on a dramatically

shortened time-frame and at a much lower cost than traditional drug development, helping

patients reduce suffering. 780.00

Mergers and AcquisitionsThe following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous

month.

Compiled by: Sumerjit Sandhu

Source: Pitchbook 17

Page 18: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Acquirer Target HQ Location Date DescriptionTransaction

Value (Millions)

Mergers and AcquisitionsThe following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous

month.

Air Liquide Oxymaster Bogotá, Colombia 24-Jan-2017

Provider of home oxygen therapy and sleep therapy services using appropriate biomedical

equipment, technologies and the support of qualified and suitable personnel, enabling the

patients and clients to access timely and quality services. Undisclosed

Bruker Hysitron Minneapolis, MN 24-Jan-2017

Developer, manufacturer and seller of nanomechanical test instruments to measure

mechanical properties of materials at the nanoscale. Undisclosed

Edwards Lifesciences Valtech Cardio Or Yehuda, Israel 23-Jan-2017 Developer of implanted cardiac devices for mitral valve repair and replacement. 690.00

Omicia Spiral Genetics Seattle, WA 23-Jan-2017

Developer of a bioinformatics software designed to detect structural variants from next-

generation sequencing data, enabling medical, pharmaceutical and agricultural research

organizations to analyse DNA data. Undisclosed

Leap Therapeutics MacroCure Radnor, PA 23-Jan-2017

Developer of a novel biopharmaceutical platform to address chronic and hard-to-heal

wounds, such as diabetic foot ulcers and venous leg ulcers. Undisclosed

Samepage Health Health123 Seattle, WA 23-Jan-2017

Developer of a health intelligence platform designed to support clinical workflows and

engage patients in plans of care, providing patients with curated content, atomized care

plans and direct connections to their care team enabling patients to have a better health

literacy and empowerment for better health, satisfaction and loyalty. Undisclosed

GetWellNetworks

Seamless Medical

Systems Santa Fe, NM 20-Jan-2017

Developer of a mobile enterprise communications platform designed to exchange patient

data between EMR and practice management systems. The company's platform allows

online scheduling and pre-registration, moves to the point of care with paperless

registration, insurance verification and payment, and continues with patient

communications and ongoing practice marketing, queue management and patient surveys. Undisclosed

Tethicon

Megadyne Medical

Products Draper, UT 20-Jan-2017

Manufacturer of electrosurgical tools created to save time and cost for surgeons, nurses,

and hospitals. Undisclosed

Ginkgo Bioworks Gen9 Cambridge, MA 20-Jan-2017

Developer of next-generation gene synthesis that automates production of DNA constructs

and improve genes, pathways, genomes and organisms using synthetic biology techniques. Undisclosed

Generex Biotechnology

Hema Diagnostic

Systems Miramar, FL 19-Jan-2017

Manufacturer of proprietary infectious disease detection devices for HIV/AIDS,

tuberculosis, malaria and other infectious diseases. 15.00

AssistRx Caret (US) Ann Arbor, MI 19-Jan-2017

Provider of a web-based care management platform that provides state-of-the-art

technology supporting point-of-service decision making, unique specialty pharmacy care

management programs and near real-time updates on activities and interactions with

patients. Undisclosed

Compiled by: Sumerjit Sandhu

Source: Pitchbook 18

Page 19: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Acquirer Target HQ Location Date DescriptionTransaction

Value (Millions)

Mergers and AcquisitionsThe following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous

month.

Instrumentation

Laboratory Accriva Diagnostics San Diego, CA 19-Jan-2017

Manufacturer of point-of-care hemostasis management products designed to focus on

creating best-in-class products that provide more timely, precise information, leading to

improved treatment outcomes. Undisclosed

Zydus Cadila Sentynl Therapeutics Solana Beach, CA 18-Jan-2017

Provider of pharmaceutical prescription products to treat pain and other central nervous

system conditions through innovative therapeutics. 171.00

Aprima Medical Software

Healthcare Data

Solutions (Healthcare

Technology Systems) Coral Gables, FL 18-Jan-2017

Provider of health technology information services to physician groups to implement and

support their ongoing system needs such as telemedicine, patient portal and other related

services. Undisclosed

AJ Biologics

Statens Serum

Institute (Vaccine

Production Business)

Copenhagen,

Denmark 16-Jan-2017 Manufacturer of vaccines. Undisclosed

Kitov Pharmaceuticals TyrNovo Kiryat-Shmona, Israel 13-Jan-2017 Developer of small molecular drugs for the treatment of cancer and inflammation diseases. 3.80

Alfasigma Pamlab Covington, LA 13-Jan-2017 Developer of prescription pharmaceuticals addressing elevated homocysteine levels. Undisclosed

Hu-Friedy Manufacturing Palmero Stratford, CT 13-Jan-2017

Producer and distributor of infection control, barriers, safety eye wear and other infection

prevention and safety related products for dental care. Undisclosed

Yungjin Pharm KT&G Life Sciences

Suwon-si, South

Korea 13-Jan-2017

Developer of medicines and drugs for treating cancer, obesity, Type 2 diabetes, liver

disease, MELAS syndrome, dry eye syndrome, atopic dermatitis and other metabolic

diseases. 38.50

MCG Health

Work Loss Data

Institute Encinitas, CA 12-Jan-2017

Provider of healthcare data and guidelines to the workers' compensation industry. The

company provides its services to insurance companies, employers, healthcare providers and

state-run agencies. Undisclosed

ÅF

Quality Engineering

Group Gävle, Sweden 12-Jan-2017

Provider of project quality management, consultancy, analysis and other related services for

the energy, life science and process industries. Undisclosed

M Pharmaceutical 40 J's Cincinnati, OH 12-Jan-2017 Developer of medical and pharmaceutical drugs. 5.50

TRIOSE

Predicata Healthcare

Solutions Riverside, RI 11-Jan-2017 Provider of actionable and smart analytic services to hospitals. Undisclosed

Compiled by: Sumerjit Sandhu

Source: Pitchbook 19

Page 20: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Acquirer Target HQ Location Date DescriptionTransaction

Value (Millions)

Mergers and AcquisitionsThe following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous

month.

Galenica Pharmapool Widnau, Switzerland 11-Jan-2017

Wholesaler of pharmaceutical products, such as medicines, medical equipment, laboratory

articles, toiletries and related products. 27.64

Derma Sciences Medihoney Richlands, Australia 11-Jan-2017

Manufacturer of honey-based medicines that provides antibacterial and anti-inflammatory

treatments. 18.25

Pharmaron Xceleron Germantown, MD 10-Jan-2017

Provider of bio analytical accelerator mass spectrometry services for drug development.

The company conducts micro-dosing, pre-clinical evaluation, intravenous pharmacokinetics,

metabolite profiling and mass balance investigations in humans. Undisclosed

Chembio Diagnostics RVR Diagnostics Subang Jaya, Malaysia 10-Jan-2017 Manufacturer and supplier of diagnostic products. 3.50

Roche Holdings ForSight Labs Menlo Park, CA 10-Jan-2017

Developer of ophthalmic technology to improve the sight, care and life of visually impaired

patients. Undisclosed

Mettrum Bodystream Barrie, Canada 10-Jan-2017

Operator of medical cannabis clinics offering cannabis-based therapies that are used to treat

a host of conditions, including chronic pain from cancer, rheumatoid arthritis and

fibromyalgia, neurological conditions like epilepsy and multiple sclerosis, Crohn's Disease,

IBS and other bowel conditions. 1.00

QIAGEN OmicSoft Cary, NC 09-Jan-2017

Provider of multi-omics data management infrastructure services to pharmaceutical and

biotech companies, universities, hospitals and research institutes to research disease causes,

discover drugs for genetic diseases and understand human genome. Undisclosed

RXi Pharmaceuticals MirImmune Cambridge, MA 09-Jan-2017

Developer of immunotherapy treatments for long-term survival of cancer patients by

combining two main approaches to cancer treatment: immune checkpoint inhibition and

cell-based immunotherapies. Undisclosed

PENTAX Medical C2 Therapeutics Redwood City, CA 09-Jan-2017 Provider of ablation therapies to improve treatment of precursors to esophageal cancer. Undisclosed

Pamplona Capital

Management and

Northwell Health Formativ Health New York, NY 06-Jan-2017

Developer of revenue cycle management services, patient access services, physician practice

management and advisory services to its clients in the healthcare industry. Undisclosed

Invitae AltaVoice San Mateo, CA 06-Jan-2017

Provider of patient insight networks that collect, curate and share patient and clinician

reported health data. 15.00

Georgia Healthcare Group ABC Pharmacia Tbilisi, Georgia 06-Jan-2017 Retailer and wholesaler of pharmaceutical goods. 25.00

Compiled by: Sumerjit Sandhu

Source: Pitchbook 20

Page 21: Monthly Healthcare Review January 2017 - BioEnterprise · Amblyotech 24-Jan-2017 Marietta, GA Angel Developer of an electronic media application designed to treat amblyopia and other

Monthly Healthcare Review

January 2017

Acquirer Target HQ Location Date DescriptionTransaction

Value (Millions)

Mergers and AcquisitionsThe following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous

month.

Frontier Capital AccessOne Charlotte, NC 05-Jan-2017

Provider of a technology-enabled financial engagement platform that offers patient

payment options designed for patient consumers to manage their healthcare costs. Undisclosed

Abbott Laboratories St. Jude Medical Saint Paul, MN 04-Jan-2017

Manufacturer of medical devices in clinical areas of cardiac rhythm management, atrial

fibrillation, cardiovascular and neuromodulation. 25,000.00

Bruker

InVivo Biotech

Services

Hennigsdorf,

Germany 04-Jan-2017

Provider of monoclonal antibodies and recombinant proteins. The company offers a

complete range of biotech services, from cloning, screening and recombinant expression of

antigens, to the generation of hybridoma cell lines and from characterization of antibodies,

to final production of the developed monoclonal antibodies. Undisclosed

ConvaTec EuroTec Beheer

Roosendaal,

Netherlands 04-Jan-2017

Producer of stoma care products. The company specializes in the manufacturing of

colostoma, ileostoma, urostoma, kinderzakjes and ostomate. 26.55

GE Healthcare

Rapiscan Pharma

Solutions Palo Alto, CA 03-Jan-2017

Manufacturer of a pharmacological stress agent that simulates the effects of exercise in the

hearts of adult patients and offers an alternative screening method for patients who are

unable to undergo traditional cardiac stress imaging procedures. Undisclosed

DePuy Synthes Interventional Spine Irvine, CA 03-Jan-2017

Developer of a percutaneous transfacet compression device for posterior stabilization of

the cervical spine. It also provides a family of expandable cages that are used in spinal

fusion surgery to restore the natural disc height that is designed to provide optimal tactile

feedback for the surgeon. Undisclosed

Natus Medical GN Otometrics Taastrup, Denmark 03-Jan-2017

Manufacturer of hearing instrument fitting, audiologic diagnostics, audiological test

equipment and audio measuring equipment. 145.00

McKesson Pharmacy

Optimization Pharmatek Systems Parsippany, NJ 01-Jan-2017

Provider of hospital pharmaceutical cost containment software and services to healthcare

providers and health systems. Undisclosed

Consumer Healthcare

Business of Boehringer

Ingelheim

Boehringer Ingelheim

(consumer healthcare

business)

Ingelheim / Rhein,

Germany 01-Jan-2017

Developer of medicines for cough and cold, sore throat, general pain, gastro-intestinal

disorders and vitamins and minerals for physical and mental well-being. 8,000.00

Compiled by: Sumerjit Sandhu

Source: Pitchbook 21