in theTreatmentof Pediatric

NeurologicalDisorders

A Conference Honoring

James R. Gage, M.D.

I N A UGURA L P E D I AT R I C N EU RO S C I E N C E S CON F E R EN C E

May 15 – 17, 2008Minneapolis Convention Center

Minneapolis, Minn.

Moving Forward

Course DescriptionThis course is designed to increaseproviders’ understanding of the basicscience, evidence and research in pediatricneurological disorders and how researchtranslates into clinical practice. The formatwill combine large-group plenary sessionswith breakout sessions of smaller groups.Such a format allows communication andinterchange among professionals fromdifferent disciplines who work with patientswho have neurological disorders.

The first two days will focus primarily oninjuries to the developing brain and centralnervous system. The third day will focuson congenital and acquired injuries to theneuromuscular/peripheral nervous system.

Overall Course Objectives:� To identify current scientific advancesin the area of pediatric neurologicaldisorders

� To translate research into clinical carefor patients who have cerebral palsy,acquired brain injuries, neuromusculardisorders and other neurologicalconditions

� To examine the clinical benefits of inter-disciplinary management of childrenwith neurological disorders

� To examine emerging trends in thetreatment of patients with neurologicdisorders and injuries

� To understand the lifelong needs ofpatients who have childhood neuro-logical disorders

Accreditation and Certificatesof AttendanceGillette Children’s Specialty Healthcareis accredited by the Minnesota MedicalAssociation to provide continuing medicaleducation (CME) for physicians. Gillettetakes responsibility for the content, qualityand scientific integrity of this activity.

Gillette designates this educationalactivity for a maximum of 17.5 AMA PRACategory 1 Credits™ for physicians.Physicians should only claim creditcommensurate with the extent of theirparticipation in the activity.

An application for CME credit has beenfiled with the American Academy ofFamily Physicians; determination of creditis pending.

This activity has been designed to meetMinnesota Board of Nursing continuingeducation requirements for 21 contacthours. Nurses are responsible for deter-mining whether this activity meets theirrequirements for acceptable continuingeducation.

This CME-accredited activity meets therequirements of continuing educationcredit for physical therapists. If you havequestions, please contact your stateboard.

On behalf of orthotists, the sponsors ofthis workshop have filed a request withthe American Board for Certification inOrthotics, Prosthetics and Pedorthics for17.5 hours of continuing education credit.

Inaugural Pediatric Neurosciences ConferenceThis conference is intended for pediatric specialists, primary-care physicians, physicaland occupational therapists, speech and language pathologists, nurse practitioners,nurses, physician assistants and orthotists.

This conference honors the many efforts ofJames R. Gage, M.D., to improve the well-being of children with cerebral palsy.

Dr. Gage attended Northwestern University MedicalSchool and completed a residency in orthopaedicsurgery at the Minneapolis Veterans Administration Hospital in 1971 afterserving in the U.S. Navy. In 1976 the Gage family moved to Connecticut,where Dr. Gage became a pediatric orthopaedist at Newington Children’sHospital. Dissatisfied with the outcomes of care for gait disturbances inchildren with cerebral palsy, Dr. Gage developed an interest in the use ofcomputer technology in the assessment of human walking. After collabo-ration with David Sutherland, M.D., of San Diego Children’s Hospital, Dr.Gage encouraged United Technologies Research Center to build one of theworld’s first fully automated motion laboratories at Newington Children’s.A second laboratory followed at Gillette in 1987, and Dr. Gage returned toMinnesota in 1990 to serve as Gillette’s medical director. But these simplefacts are inadequate.

Dr. Gage’s unwillingness to accept mediocrity as inevitable profoundlychanged the care of children with cerebral palsy. He insisted that thebaffling complexity of spastic walking could be approached by the applica-tion of basic tools: careful examination of a child, measurement by motionanalysis, establishment of goals, single-event surgeries that correctedmultiple problems at once, good rehabilitation, and meticulous measure-ment and assessment of treatment outcomes. Dr. Gage solicited theinvolvement of individuals from multiple clinical domains, including neuro-logy, neurosurgery, physiatry, physical therapy, mechanical engineering andorthotics. As a result of his persistence and diligence, the current conceptof first managing a child’s tone and then addressing the skeletal and mus-cular consequences of that tone emerged.

It has been our great fortune to be Dr. Gage’s students and colleaguesday in and day out. Through his willingness to teach and collaborate, hisconcepts have spread, to the benefit of countless children.

RecognizingJames R. Gage, M.D.

I N A U G U R A L P E D I AT R I C N E U R O S C I E N C E S C O N F E R E N C E

- Steven E. Koop, M.D., Medical DirectorGillette Children’s Specialty Healthcare

I N A U G U R A L P E D I AT R I C N E U R O S C I E N C E S C O N F E R E N C E

Agenda Thursday, May 15, 2008

7:00 to 8:00 a.m. Registration

8:00 to 8:15 a.m. Welcome and IntroductionSteven E. Koop, M.D.Gillette Children’s Specialty Healthcare

8:15 to 9:15 a.m. Brain Injuries in the Newborn InfantAdre J. du Plessis, M.D.Boston Children’s Hospital

9:15 to 10:00 a.m. Neuroimaging in the NewbornMartin J. Asis, M.D.St. Paul Radiology

10:00 to 10:30 a.m. Morning Break and Exhibits

10:30 to 11:15 a.m. Brain Cooling in Perinatal AsphyxiaRobert J. Couser, M.D.Minnesota Neonatal Physicians

11:15 a.m. to Noon Neonatal HydrocephalusJeffrey P. Blount, M.D.University of Alabama at Birmingham

Noon to 1:20 p.m. Lunch and Exhibits

1:20 to 2:05 p.m. Session A

Clinical Manifestations of SeizuresBeverly S. Wical, M.D.Gillette Children’s Specialty Healthcare

Session B

Cognitive Development and Executive Functioning, Part IMartha S. Burns, Ph.D., S.L.P.Northwestern University

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2:10 to 2:55 p.m. Session A

Non-Pharmacologic Management of SeizuresShani K. Norberg, M.D., and Karri M. Larson, R.D.Gillette Children’s Specialty Healthcare

Session B

Mild Traumatic Brain Injuries and Multiple-Concussion SyndromeMark E. Gormley Jr., M.D.Gillette Children’s Specialty Healthcare

2:55 to 3:25 p.m. Afternoon Break and Exhibits

3:25 to 4:10 p.m. Session A

Surgical Interventions for Children With EpilepsyJeffrey P. Blount, M.D.University of Alabama at Birmingham

Session B

Severe Traumatic Brain Injury: Rehabilitation Techniquesand Outcomes

Linda E. Krach, M.D.Gillette Children’s Specialty Healthcare

4:15 to 5:00 p.m. Session A

Sleep Disorders in Children With Injuries to the BrainJohn J. Garcia, M.D.Gillette Children’s Specialty Healthcare

Session B

Cognitive Development and Executive Functioning, Part IIMartha S. Burns, Ph.D., S.L.P.Northwestern University

5:00 to 6:30 p.m. Welcome ReceptionSeasons RoomMinneapolis Convention Center

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Agenda Friday, May 16, 2008

7:00 to 8:00 a.m. Registration

8:00 to 8:45 a.m. Progress in the Treatment of Cerebral Palsy: Reflections ona 30-Year Career

James R. Gage, M.D.Gillette Children’s Specialty Healthcare

8:45 to 9:30 a.m. Neurosurgery in Cerebral Palsy: Knives, Needlesand Neurotransmitters

A. Leland Albright, M.D.University of Wisconsin – Madison

9:30 to 10:00 a.m. Morning Break and Exhibits

10:00 to 10:45 a.m. Advanced Pediatric NeuroimagingMartin J. Asis, M.D.St. Paul Radiology

10:45 to 11:30 a.m. Neural Plasticity and Neurological DiseaseJeffrey A. Kleim, Ph.D.University of Florida

11:30 a.m. to Lunch and Exhibits1:00 p.m.

1:00 to 1:45 p.m. Session A

Use of Motion Lab Analysis in Evaluation and Treatmentof the Upper Extremity in Spastic Hemiplegia Due toCerebral Palsy

Ann E. Van Heest, M.D.Gillette Children’s Specialty Healthcare

Session B

The Multidisciplinary Spasticity Evaluation Clinic:How the Team Approach at Gillette Works

Tom F. Novacheck, M.D., Michael D. Partington, M.D.,and Marcie E. Ward, M.D.

Gillette Children’s Specialty Healthcare

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1:50 to 2:35 p.m. Session A

Trends in Rehabilitation Therapy for Children WithCerebral Palsy

Jason M. Kelecic, D.P.T., Tonya L. Rich, M.A., O.T.R./L., andSusan E. Toavs, M.S., C.C.C.

Gillette Children’s Specialty Healthcare

Session B

Assessment of Movement Disorders Using Motion AnalysisMark E. Gormley Jr., M.D., and Cammie F. Beattie, P.T.Gillette Children’s Specialty Healthcare

2:35 to 3:05 p.m. Afternoon Break and Exhibits

3:05 to 3:50 p.m. Session A

Anoxic Seizures and Anoxic-Epileptic SeizuresGalen N. Breningstall, M.D.Gillette Children’s Specialty Healthcare

Session B

Outcomes of Spasticity Reduction for Children WithCerebral Palsy: Maximizing Efficacy, Minimizing Risk

Tom F. Novacheck, M.D.Gillette Children’s Specialty Healthcare

3:55 to 4:40 p.m. Session A

Transitioning Patients With Developmental Disabilities toAdult-Focused Health Care

Robert J. Wagner, M.D.Gillette Lifetime Specialty Healthcare

Session B

Correction of Growth Deformities and Reduction of Spasticity:Not Just Two Different Roads to the Same Destination

James R. Gage, M.D., and Steven E. Koop, M.D.Gillette Children’s Specialty Healthcare

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Agenda Saturday, May 17, 2008

7:00 to 8:00 a.m. Registration

8:00 to 8:45 a.m. New Directions in the Diagnosis and Treatment of DuchenneMuscular Dystrophy

Kevin M. Flanigan, M.D.University of Utah

8:45 to 9:30 a.m. Mitochondrial Disorders in ChildrenBruce H. Cohen, M.D.Neuroscience InstituteThe Cleveland Clinic

9:30 to 10:00 a.m. Morning Break

10:00 to 10:45 a.m. Enzyme Replacement in Pompe Disease: Lessons forNeurologic Lysosomal Disorders

Lawrence R. Charnas, M.D., Ph.D.University of Minnesota – School of Medicine

10:45 to 11:30 a.m. Spinal Muscular AtrophyThomas O. Crawford, M.D., Ph.D.Johns Hopkins Medical School

11:30 a.m. to Lunch1:00 p.m.

1:00 to 1:45 p.m. Session A

Birth Brachial Plexus Injuries: Evaluation and TreatmentAnn E. Van Heest, M.D., and Marshall H. Taniguchi, M.D.Gillette Children’s Specialty Healthcare

Session B

Primary and Secondary Central Nervous System Effects ofNeuromuscular Disease

John W. Day, M.D., Ph.D.Gillette Children’s Specialty Healthcare

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1:50 to 2:35 p.m. Session A

Advanced Reconstructive Techniques in Brachial PlexopathyRobert J. Spinner, M.D.Mayo Clinic

Session B

The Emotional and Family Burden of Neuromuscular DiseaseStephen A. Smith, M.D.Gillette Children’s Specialty Healthcare

2:35 to 3:05 p.m. Afternoon Break

3:05 to 3:50 p.m. Session A

Neuropalliative Care: Defining Goals of Care to GuideMedical Decisions

Julie A. Hauer, M.D.Gillette Children’s Specialty Healthcare

Session B

Respiratory Assessment and Ventilatory Options inNeuromuscular Disease

Paul T. Kubic, M.D.Gillette Children’s Specialty Healthcare

3:55 to 4:40 p.m. Session A

Trends in Rehabilitation for Patients With Spinal Cord InjuriesMarshall H. Taniguchi, M.D.Gillette Children’s Specialty Healthcare

Session B

Ethical Issues Related to Children With Neurological DisordersDon C. Postema, Ph.D.Gillette Children’s Specialty Healthcare

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Conference Location

Minneapolis Convention Center1301 2nd Ave. S.Minneapolis, MN 55403

Lodging

Hyatt Regency Minneapolis1300 Nicollet MallMinneapolis, MN 55403

For hotel reservations, call 612-370-1234or 800-233-1234 (toll-free). Refer to theGillette Neurosciences Conference.

Single Occupancy: $139Double Occupancy: $164Triple Occupancy: $189Quadruple Occupancy: $214

Room rates and availability applyto reservations made beforeApril 23, 2008.

Conference Information

For information on course content,call Sue Murr at 651-290-8712 or800-719-4040 (toll-free). Or visit ourWeb site at www.gillettechildrens.org.For registration information, call Amy K.Schall at 651-265-7387 or 800-719-4040(toll-free).

Visitor InformationWhile you’re in the Twin Cities, enjoythe charm and amenities that our rivercities have to offer. For information onTwin Cities attractions, please contactthe following tourism associations:

� The Greater Minneapolis Conventionand Visitors Bureau

612-661-4700www.minneapolis.org

� Minnesota Office of Tourism651-296-5029 or888-868-7476 (toll-free)www.exploreminnesota.com

� The Saint Paul Convention andVisitors Bureau

651-297-6985 or800-627-6101 (toll-free)www.stpaulcvb.org

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I N A U G U R A L P E D I AT R I C N E U R O S C I E N C E S C O N F E R E N C E

Early-Bird Registration Regular Registration(On or before April 1) (April 2 – May 1)

Physician (three days) � $550 � $595

Physician (May 15 only) � $195 � $220

Physician (May 16 only) � $195 � $220

Physician (May 17 only) � $195 � $220

Allied Health (three days) � $500 � $545

Allied Health (May 15 only) � $175 � $190

Allied Health (May 16 only) � $175 � $190

Allied Health (May 17 only) � $175 � $190

__________________________________________________________________________Name Profession

__________________________________________________________________________Specialty Organization

__________________________________________________________________________Address

__________________________________________________________________________City State/Country ZIP/Postal Code

__________________________________________________________________________Phone E-mail

� I have special needs (accessibility, diet, etc.). All requests will be kept confidential.

__________________________________________________________________________

_________________________________________________________________________

NOTE: Online registration is available at www.gillettechildrens.org.

Conference Registration FormMoving Forwardin the Treatment of Pediatric Neurological DisordersMay 15 – 17, 2008 � Minneapolis Convention Center, Minneapolis, Minn.

*Discounts apply for three-day and early-bird registrations.Your registration fee — minus a $100 administrative charge — is refundable afterthe conference if cancellation is received 48 hours before the program date.

Registration Fees*

Clipandmailthisregistrationformtoday!

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REMINDER! On the back of this form, please check which breakoutsessions you’d like to attend.

I N A U G U R A L P E D I AT R I C N E U R O S C I E N C E S C O N F E R E N C E

REGISTRATIONDEADLINES!

EARLY-BIRDApril 1, 2008

FINALMay 1, 2008

Breakout SessionsDay 1Thursday, May 15

1:20 to 2:05 p.m.� Session A (Wical)� Session B (Burns)

2:10 to 2:55 p.m.� Session A (Norberg,

Larson)� Session B (Gormley)

3:25 to 4:10 p.m.� Session A (Blount)� Session B (Krach)

4:15 to 5:00 p.m.� Session A (Garcia)� Session B (Burns)

Social Event — Welcome Reception — (hors d’oeuvres and beverages)

Thursday, May 15, 5:00 to 6:30 p.m.Seasons Room, Minneapolis Convention Center

� I will attend and __________ guests* will attend. � No, I will not attend.

*Conference participants attend at no charge; guests are $15 per person.

Payment Information

Total Amount Due: $ ____________ (includes registration and reception fees)

Make check payable in U.S. dollars to: Gillette Children’s Specialty Healthcare

Or provide credit card information.

� Check enclosed � Visa � MasterCard � Discover

Card Number _____________________________________ Exp. Date ________________

Cardholder’s Name (print) ____________________________________________________

Cardholder’s Signature ______________________________________________________

Mail payment to: Amy K. Schall, Continuing Medical EducationGillette Children’s Specialty Healthcare200 University Ave. E., St. Paul, MN 55101

Day 3Saturday, May 17

1:00 to 1:45 p.m.� Session A (Van Heest,

Taniguchi)� Session B (Day)

1:50 to 2:35 p.m.� Session A (Spinner)� Session B (Smith)

3:05 to 3:50 p.m.� Session A (Hauer)� Session B (Kubic)

3:55 to 4:40 p.m.� Session A (Taniguchi)� Session B (Postema)

Day 2Friday, May 16

1:00 to 1:45 p.m.� Session A (Van Heest)� Session B (Novacheck,

Partington, Ward)

1:50 to 2:35 p.m.� Session A (Kelecic,

Rich, Toavs)� Session B (Gormley,

Beattie)

3:05 to 3:50 p.m.� Session A (Breningstall)� Session B (Novacheck)

3:55 to 4:40 p.m.� Session A (Wagner)� Session B (Gage, Koop)

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FacultyA. Leland Albright, M.D.Pediatric NeurosurgeonUniversity of Wisconsin – MadisonMadison, Wis.

Martin J. Asis, M.D.RadiologistSt. Paul RadiologySt. Paul, Minn.

Cammie F. Beattie, P.T.Physical TherapistGillette Children’s Specialty HealthcareSt. Paul, Minn.

Jeffrey P. Blount, M.D.NeurosurgeonUniversity of Alabama at BirminghamBirmingham, Ala.

Galen N. Breningstall, M.D.Pediatric NeurologistGillette Children’s Specialty HealthcareSt. Paul, Minn.

Martha S. Burns, Ph.D., S.L.P.Adjunct Associate ProfessorNorthwestern UniversityEvanston, Ill.

Lawrence R. Charnas, M.D., Ph.D.Associate Professor of PediatricsUniversity of Minnesota – School ofMedicine

Minneapolis, Minn.

Bruce H. Cohen, M.D.Neuroscience InstituteThe Cleveland ClinicCleveland, Ohio

Robert J. Couser, M.D.NeonatologistMinnesota Neonatal PhysiciansMinneapolis, Minn.

Tom O. Crawford, M.D., Ph.D.Pediatric NeurologistJohns Hopkins Medical SchoolBaltimore, Md.

John W. Day, M.D., Ph.D.NeurologistGillette Children’s Specialty HealthcareSt. Paul, Minn.

Kevin M. Flanigan, M.D.Associate Professor of NeurologyUniversity of UtahSalt Lake City, Utah

James R. Gage, M.D.Pediatric Orthopaedic SurgeonGillette Children’s Specialty HealthcareSt. Paul, Minn.

John J. Garcia, M.D.Sleep Medicine SpecialistGillette Children’s Specialty HealthcareSt. Paul, Minn.

Mark E. Gormley Jr., M.D.Pediatric Medicine Rehabilitation PhysicianGillette Children’s Specialty HealthcareSt. Paul, Minn.

Julie A. Hauer, M.D.PediatricianGillette Children’s Specialty HealthcareSt. Paul, Minn.

Jeffrey A. Kleim, Ph.D.Associate Professor of NeuroscienceUniversity of FloridaGainesville, Fla.

Steven E. Koop, M.D.Pediatric Orthopaedic SurgeonMedical DirectorGillette Children’s Specialty HealthcareSt. Paul, Minn.

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Linda E. Krach, M.D.Pediatric Medicine Rehabilitation PhysicianGillette Children’s Specialty HealthcareSt. Paul, Minn.

Paul T. Kubic, M.D.PulmonologistGillette Children’s Specialty HealthcareSt. Paul, Minn.

Karri M. Larson, R.D.Registered DietitianGillette Children’s Specialty HealthcareSt. Paul, Minn.

Shani K. Norberg, M.D.Pediatric NeurologistGillette Children’s Specialty HealthcareSt. Paul, Minn.

Tom F. Novacheck, M.D.Pediatric Orthopaedic SurgeonGillette Children’s Specialty HealthcareSt. Paul, Minn.

Michael D. Partington, M.D.Pediatric NeurosurgeonGillette Children’s Specialty HealthcareSt. Paul, Minn.

Adre J. du Plessis, M.D.Pediatric NeurologistBoston Children’s HospitalBoston, Mass.

Don C. Postema, Ph.D.EthicistGillette Children’s Specialty HealthcareSt. Paul, Minn.

Stephen A. Smith, M.D.Pediatric NeurologistGillette Children’s Specialty HealthcareSt. Paul, Minn.

Marshall H. Taniguchi, M.D.Pediatric Medicine Rehabilitation PhysicianGillette Children’s Specialty HealthcareSt. Paul, Minn.

Ann E. Van Heest, M.D.Orthopaedic SurgeonGillette Children’s Specialty HealthcareSt. Paul, Minn.

Robert J. Wagner, M.D.Family MedicineGillette Lifetime Specialty HealthcareSt. Paul, Minn.

Marcie E. Ward, M.D.Pediatric Medicine Rehabilitation PhysicianGillette Children’s Specialty HealthcareSt. Paul, Minn.

Beverly S. Wical, M.D.Pediatric NeurologistGillette Children’s Specialty HealthcareSt. Paul, Minn.

I N A U GU R A L P E D I AT R I C N E U R O S C I E N C E S C ON F E R E N C E

Planning CommitteeLynn S. Carpentier

Patrick S. Cavanaugh, R.N.

Suzanne M. Constantini

John W. Day, M.D., Ph.D.

Paul J. Fiore

James R. Gage, M.D.

Randa G. Jarrar, M.D.

Jason M. Kelecic, D.P.T.

John E. Lonstein, M.D.

Jennifer C. Maytum, R.N., C.N.P.

Sue Murr, P.T., P.C.S.

Michael D. Partington, M.D.

Amy K. Schall

Stephen A. Smith, M.D.

Jean L. Stout, P.T.

Susan E. Toavs, M.S., C.C.C.

Candace F. Vegter, M.A., C.C.C.

Kathryn J. Wardrop

Beverly S. Wical, M.D.

Members of the ContinuingMedical Education Committee atGillette Children’sSpecialty Healthcare

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May15–17,2008

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NeurologicalDisorders

Moving

Forward