Innovation with Integrity

MPA – Simply ONE FT-NIR™ for DairyONE Instrument. ONE Software Package. ONE Partner.

FT-NIR

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Simply ONE FT-NIR™ Technology for Dairy Manufacturers by BrukerONE Instrument. ONE Software Package. ONE Partner.

Before the introduction of Bruker‘s Simply ONE FT-NIR™ Technology, multiple instruments were required; FT-IR for fluids such as milk and whey, NIR for powders and grated samples, and NIT for samples such as yogurt, cottage cheese and puddings.

The Bruker MPA Dairy system is configured to test the full range of dairy products.

•Simplifyroutinetesting–Shorterlearningcurve.•RealizefasterROI–ALLProducts.ALLParameters.•Eliminateneedtocrosstrainonmultipleinstruments.•Minimizerisk–StreamlineFSMAcompliance.•Obtaindatafromstarttofinishtosupportleanmanufacturingandsixsigmainitiatives.

Quality Ingredients and RawMaterials In-Process Testing Final Products and

Co-ProductsSoftware and Regulatory

Compliance

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Bruker FT-NIR for Dairy

Make the Switch to FT- NIRFourier Transform (FT) technology applied to the Near Infrared(NIR)spectralregiondeliversthesameperformanceadvantagesthatrevolutionizedmeasurementsintheInfrared(IR) region more than 30 years ago.

FT-NIR instruments offer distinct advantages over FT-IR:•Measurelargervolumetoaverageoutsample

inhomogeneity

•Quartzflowcellsforliquidmeasurementsarewear-free.Nocalibrationdriftorcellreplacementrequired

•Routinemeasurementofhighviscositysamplesthankstolargertubeandflowcelldiameter

•Everyinstrumentisamaster.Seamlesslytransfercalibrationsbetweendifferentinstruments

Exceptionalprecisionandaccuracy,coupledwithsignificantlyimprovedsensitivityandspeedofBruker‘sFT-NIRinstrumentsallowsmeasurementofovertonesandcombinationbandsoftheverysamesignalsusedtomeasuredairy products with FT-IR instruments.

RockSolid™ InterferometerThe heart of Bruker‘s Simply ONE FT-NIR™istheRockSolidInterferometer,basedon

Corner-Cubetechnology.Thisdesignensuresthatthealignmentintheopticsneverchanges,

eliminating the need for continual adjustments.

ACorner-Cubearraywasplacedonthemoonin1969byApollo11

astronauts. Without any adjustments, it is still going strong today measuring

thedistancebetweentheearthandthemoonwithin2cmaccuracy.

FormoreinformationontheCorner-Cubeonthemoon,visit

http://www.jpl.nasa.gov/m/news/news.php?feature=605#.UzxDl16j5yF.

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Simply ONE FT-NIR™ Technology for Incoming Raw Materials by BrukerONE Instrument. ONE Software Package. ONE Partner.

AkeyFT-NIRadvantage:largerdiametertubingwithlargevolumetransmissionsamplecelleasilyhandleshighviscositysamples like condensed milk or ice creammixwithoutproducingexcessivebackpressureinthesystem.3�

Virtually No Sample Preparation. Cheese, grated samples, powders and thick samples such as yogurts and cultured products are simply placed in a sample dish. The dish is rotated during the measurement, insuring that theresultisrepresentativeoftheentiresample.4

LiquidSamplingModule(LSM).RoutinemaintenancefortheLSMiseasy.AllserviceablecomponentsarelocatedonthefrontoftheLSMforeasyaccessand exchange.3

For in-homogenous samples, rotating cupsareusedtoaveragelargesampleareasforimprovedsamplingofrepresentativematerial.4

Awidevarietyofsampledishesisavailabletosuitanyrequirements–fromdisposablepolystyrenedishesforfast sampling with no cleanup, to cups withwater-freequartzwindowswhenultimatesensitivityisrequired.

sippertubeandlevelsensor

high pressure pump

peristaltic pump

•Testandstandardizeincomingingredients

•Sequesterout-of-specmaterials•Keepscorecardsforvendor

performance• Initiatemassbalancecalculations•StreamlinecompliancewithFSMA

•Screenforeconomicallymotivatedadulteration(EMA)

BrukerFT-NIRforDairy In-Process Testing Final Products and Co-Products

Software and Regulatory Compliance

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Quality Ingredients and Raw Materials

More Than Milk

Often, the first manufacturing steps are skimming off the cream and then ultra filtration of the skim milk. CreamandUFskimmilkarethenaddedtotheskimmilktostandardizethefatandproteinlevel,ensuringa consistent starting point in the production process.

TheMPADairysystemsimultaneouslyroutinelymeasuresFat,Protein,LactoseandTotalSolidsinmilk, cream, and whey with accuracy and precision comparabletothestandardreferencemethods.AnaddedadvantageofSimplyONEFT-NIR™ technology is improvedcalibrationtransferbetweenunits;longtermstabilityandlessdowntime.

FT-NIRspectralchangescorrelatewelltobutterfatdropletsize, providingasimpleandefficientdiagnostictoolforhomogenizerefficiency,takingtheguessworkoutofschedulingmaintenanceintervals.

Food Safety and Modernization Act (FSMA) critical aspects:•Supplierqualification,especiallyforeign

suppliers•Screeningforeconomicallymotivatedadulteration(EMA)

•TrendsinFreezePointDepressionandMilkUreaNitrogenmayindicateadulterationoffluid milk samples.

•Qualitativepass/failmethodsforEMAscreening and; to monitoring lot-to-lot consistency of ingredients such as:–Honey–Cocoa/Chocolate– Fruits– Flavors–Sweeteners–Starches

–Emulsifiers–Stabilizers–Packagingand

Containers–Oils–Sugars

Easy and Reliable Operation with Bruker‘s LSM•Software-controlledset-upofmethods•Customizabletotheoptimumparametersforeachsample•Setpumpingvolumesandspeedtoadjustforviscosity• Temperature-controlassuresmeasurementaccuracy•Automated,timedcleaningcyclepreventscrosscontamination•Homogenizeonlythosesamplesthatrequireit,avoidingunnecessaryoperationofhomogenizer.

Raw materials that can be analyzed using the MPA Simply ONE:

•RawMilk

•SkimMilk

•Cream

•UFMilk

•WPC

•MilkPowder

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Simply ONE FT-NIR™ Technology for In-Line Applications by BrukerONE Instrument. ONE Software Package. ONE Partner.

•OptimizeindividualUnitOperations•Controlchartingofkeyprocessparameters–Easyidentificationofout-of-specconditions– IdentifytrendsandapplycorrectionstokeepUnitOperationswithinspecifications

•UpdatedataforMassBalancecalculationsforeachUnitOperation

Rapid At-Line TestingAt-Linetestingprovidesacost-effectivewaytocontinuallyoptimizeunitoperations.SimplyONEFT-NIR™ systems allow fast, easy determination of control parameters at key pointsinproductionforeithersolids,liquids,orbothtypesofsamplesonasingleinstrument.Asingleinstrumentplacednearaseparatorcanbeusedtodeterminepercentsolids in the product feed, residual protein in the whey stream, and percent solids in the product stream.

Configure a dedicated FT-NIR for use with a singleUnitOperation,oramulti-channel instrument tosupportmultipleUnitOperations in a dairy processing plant.

The exceptional precision and accuracy of Bruker’s Simply ONE FT-NIR™ facilitates the easy transfer ofproductcalibrationsfromoneanalyzertoanother to scale up sample throughput as your production increases, or as new products are added to your portfolio.

BrukerFT-NIRforDairy Quality Ingredients and RawMaterials

Final Products and Co-Products

Software and Regulatory Compliance

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In-Process Testing

Simply ONE FT-NIR™ for In-Line Applications

Bruker’sRocksolidInterferometer,basedoncornercubemirrors, ensures that the instrument is not affected byvibration.NowitispossibletoenjoythesamehighperformanceofBruker’slaboratorysystemswithmultiplexed in-line process measurements.

•ThefullNIRspectralrangeismeasured,includingthecombinationbandregionwheresmallchangesinproteincanbereadilydiscerned

•Multiplexingforuptosixmeasurementpoints on a single instrument significantly reduces the cost per sampling point

•Minimalmaintenanceandlong-termstabilityoftheinstrumentandthecalibrations

3��Typical FT-NIR installation for measurement of fat content inbutterproduction. Similar systems are employed in extrusion processes and in separation processes for cultured dairy products.

Inatypicalspraydryingunit,theMatrixFcontinuouslymonitorsseveralparameters (e.g. fat, protein, lactose, total solids) of the liquid spray tower feed,whileprovidingfeedbacktotheunitbasedontestingthepowderatthesifterofthefluidbeddryerformoistureandseveralkeyparameters.

In-linemeasurementatkeycontrolpointsrevealsshorttermprocessvariationanddrift.Operatingclosertothesetpointwithreducedvariationimprovesyieldandconsistency,oftendeliveringROIinmonthsratherthanyears.

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Simply ONE FT-NIR™ Technology for Final Products by BrukerONE Instrument. ONE Software Package. ONE Partner.

ComputingMassBalance is a key indicator of conversionefficiencyin a dairy plant. Simply ONE FT-NIR™ lets you determine that your costly ingredients are in your products and not in a waste stream.

•QuicklyTestCompliancewithLabelClaims• InsureProductsMeetUSDAGradeRequirements•AnalyzeProductsandCo-ProductstoFinalizeMassBalanceandYieldCalculations

Dairyprocessorsplacehighdemandsoninstrumentsforprecisionandaccuracyaswellasdurabilityandease-of-use. Simply ONE FT-NIR™delivers.

Fluid Milk with Simply ONE FT-NIR™

Accuracy:Better than 0.8% CV(Fat,Protein,LactoseandTotalSolids) on raw milk

Repeatability:Better than 0.2% CV(Fat,Protein,LactoseandTotalSolids) on raw milk

BrukerFT-NIRforDairy Quality Ingredients and RawMaterials In-Process Testing Software and Regulatory

Compliance

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Final Products and Co-Products

Bruker Dairy calibrations

BrukerDairycalibrationsare the product of more than two years focusing on measurement of StandardizedMilksamples as well as other fluid dairy products obtainedfromrecognizedlaboratoriesemployingAOACapprovedreference methods.

with Simply ONE FT-NIR™

ProductSour Cream 0.5% over formulated

Sour Cream 0.1% over formulated

PlantProductionCapacity(lbs/day) 20000 20000

DaysinProduction/yr 340 340

AllowableSafetyWindow(%Fat) 0.5 0.1

ButterfatGive-Away/yr(lb) 34000 6800

ButterfatMarketPrice/lb $1.75 $1.75

AnnualButterfatGive-AwayCost $59,500.00 $11,900.00

AnnualSavingswithSimplyONEFT-NIR™ $47,600.00

Simply ONE FT-NIR™providesfastandaccuratereportingfornutritionallabeling,anddeterminationofbutterfatcontent to meet product grading standards. Over-formulation to insure that grade standards are met has asignificantnegativeimpactonmanufacturingefficiencyandproductioncosts.Adairyplantproducing20,000lbsofsourcreameachday,over-formulatingby0.5%forbutterfatcontent,hasnearly$59,500moreinannualrawmaterialcosts,andlostannualproductionof200,000lbs-witharetailvalueofmorethan$330,000.1

1BasedonButterfatpriceof$1.75/lb.andanaverageretailpriceof$1.63/lb.forSourCreamasofFebruary2014

MilkcalibrationsstandardsfromDQCIlaboratories,preheatedon40CAllMPAarepre-calibratedbasedonDQCIsamples

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Simply ONE FT-NIR™ Technology for Software and Quality Systems by BrukerONE Instrument. ONE Software Package. ONE Partner.

UsingSimplyONEFT-NIR™ couldn’t beeasier. Just select the product and you are ready to go! Everythingelseisfullyautomated–evencleaningthesample path for liquid samples.

• Intuitiveoperatorinterfacebackedbysophisticateddataevaluationmethodology

•FullinstrumentvalidationforregulatorycompliancewithIQ,OQ and PQ protocols

•PerformanceValidationToolsforISO17025CalibrationValidation

•Completedigitaldataretentionand21CFRPart11compliance

One Software Package.Whetheryourinstrumentisforin-lineprocess,abenchtopunitdedicatedtocontrollingasingleunitoperation,orinalabtoanalyzeeverything,thereisonesoftwarepackagethatdoesitall.Opusisdesignedtodelivertraceabilitytodocumentthatasamplewas measured using the correct instrument set-up, that results wereobtainedusingthecorrectevaluationmethods,andthenarchivethespectraandresultsinasinglefileforeachsample. Youcaneasilyrecallanysampledataforinternalaudits,orforexternal auditors examining your data and methods.

Powerfulevaluationtoolsextractinformationfromyoursamples–clusteranalysisforrawmaterialqualification,andPLSmethodsforquantitativeanalysis.•HierarchicalIdentificationforrawmaterialqualification•PLSQuantitativeAnalysisforcompositionalanalysis•ConformityTest•Multi-evaluationtosequenceclusterandPLSanalysisforeachsample,withtheabilitytoperformcalculationsusingthemeasuredvaluesfromthesample

BrukerFT-NIRforDairy Quality Ingredients and RawMaterials In-Process Testing Final Products and

Co-Products

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Software and Regulatory Compliance

PerformanceGuard Monitoring

PerformanceGuardcontinually monitors critical system functions, and immediately informs the operator if there is anout-of–speccondition.OQ and PQ test status is also indicated with separate results for liquid, solid and in-line measurement points.

Performance Validation for Regulatory ComplianceBrukerspectrometersandsoftwarearefullyvalidatedtomeettherequirementsofPharma,FSMAandISO17025.OurinternalqualitysystemshavebeenscrutinizedbymajorPharmaceuticalandFoodManufacturingcompanies,andfoundtobethebestintheindustry.SimplyONEinstrument performance qualification includes full OQ and PQ test protocols that are integrated into daily instrument operation. Each measurement channel has a specific set of testsandpass/failcriteria.Testsusebuilt-instandardsandcanbescheduledtoruninoff-hourssoyourinstrumentisfullyqualifiedandreadytogowhenyouarereadytobeginthe day’s measurements.

OVP - OQ Test ProtocolCompany:Operator:Instrument Type:Optics Configuration:Accessory:Instrument Serial Number:Instrument Firmw are Version:OPUS/DB Version:Overall Test ResultTest expires:Test Date/Time:Test Spectra Path:Comment:

Bruker OpticsAdminMPA SphereSphere Background w ith: NIR, Quartz, RT-PbS [External]None15352.240 Nov 16 2011OPUS 7.2 Build: 7, 2, 139, 1294 / DB: 7,2,139,1294PASSED7/25/2014, 4:06:24 PM (GMT-5)7/25/2013, 4:06:24 PM (GMT-5)C:\OPUS_7.2.139.1294\Validation\Data\20130725\160624

Resolution Test

Water Vapor Band:Maximum Resolution:

7306.74 cm-12.00 cm-1 Measured Resolution: 1.68 cm-1

Sensitivity Test

Measurement Region, Start:Minimum S/N:

4700.00 cm-11000

Measurement Region, End:Measured S/N:

4500.00 cm-13036.97

Energy Distribution Test

Minimum Energy Value:Minimum Energy Value:

Energy at 12000.00 cm-1

1.00%1.00%

1.85%

Energy at 10000.00 cm-1Energy at 3500.00 cm-1

7.43%4.68%

Wavenumber Accuracy Test Water Vapor

Expected Band:Maximum Deviation:

7306.740 cm-10.100 cm-1

Measured Band:Measured Deviation:

7306.777 cm-10.037 cm-1

Alignment Test

Interferogram Peak Range: 35000 - 28000 Measured Peak Position:Peak Amplitude:

33877-20567

Linearity Test

Maximum Energy[%]: 1.00 Measured Energy[%]: 0.43

Overall Test Result = PASSED

Date and Signature Date and Signature

Service and Support North AmericaBrukerOpticsisstaffedbyexpertscientistsand engineers with an in-depth knowledge of instrumentation and applications in the dairy industry. Ourproductspecialistsareavailabletoassistyouwithmethoddevelopmenteitherremotelyorinyourlab.

Bruker Corporation Boston, MAPhone+1(978)439-9899

Bruker Optics in Houston, TX● FT-NIR Headquarters Phone+1(281)292-2447

Bruker Optics in Madison, WIPhone+1(608)276-3800

Bruker Optics in Fremont, CAPhone+1(510)683-4335

Bruker Optics in Milton, CanadaPhone+1(905)-876-4641

Bruker Mexicana in Mexico City, MexicoPhone+52555601-2599

Bruker FT-NIR Systems

TangoFT-NIRforQA/QCApplications

MPAMulti-PurposeAnalyzer

Matrix-Iforat-lineanalysis

Matrix-Fforin-lineprocessapplications

www.bruker.com/dairy

About Bruker CorporationFormorethan50years,BrukerCorporationisdriventoalwaysprovidethebesttechnologicalsolutionforeachanalytical task.

Today,worldwidemorethan6,000employeesareworkingonthispermanentchallengeatover90locationsonallcontinents.Brukersystemscoverabroadspectrumofapplicationsinallfieldsofresearchanddevelopmentandareusedinallindustrialproduction processes for the purpose of ensuring qualityandprocessreliability.