msc handbook sem 1

7/29/2019 MSc Handbook Sem 1

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MAN OR MACHINE?

In case the need for such appliance of science in

Health Care is not obvious, let us think of the HumanBody in scientific terms as follows

The body can be regarded as a machine controlled by the worlds mostsophisticated microcomputer, about the size of a grapefruit and largely self-programmable. The machine is self-propelled in any direction with a forwardspeed of up to ~30 kmph or so but capable of only transient vertical travel toa maximum height of ~2.5 meters. It is largely waterproof, entirely rustproof

and semi-immersible. Control is effected, with automatic feedback, throughself-adjusting binoculars and by auditory, olfactory and tactile signals.

The machine is equipped with a pair of sophisticated remote manipulators.It is powered by a wide variety of fuels (ideally unleaded) via a multipurposecarburettor that is partly self-regulating. The machine can self-replicate and,though no guarantee is provided, has an expected lifetime of about 70years.

To a large extent, the machine is self-repairing. However, in the event of amalfunction, diagnosis of the problem (and its rectification) should beachieved ideally without lifting the bonnet and with minimal damage toexternal bodywork. However, no manuals relating to construction, functionor repair are provided.

Taken from the International Union for Physical and Engineering Sciences (IUPESM)chairmans supporting case for the International Federation for Medical & BiologicalEngineering (IFMBE) application for full membership of the International Council of

Scientific Unions (ICSU) published in the IFMBE news letter no 37, July 1999

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INDEX

General Information on Course and University Procedures 3

Contact numbers for Module Tutors and Lecturers 8

Course Regulations 9

A Guide for Studying 14

Overview of Timetable 17

Timetable Day by Day 18

Detailed information on modules:

MTE-40001 Biomedical Signal Processing 21

MTE-40002 Physiological Measurement and Medical Imaging 23

MTE-40003 Medical Electronics and Equipment Management 25

MTE-40005 Biosensors 26

MTE-40006 Biomaterials 28

MTE-40007 Orthopaedics and Rehabilitation 31

MTE-40009 Healthcare Technology Assessment 32

MTE-40012 Biomechanics 33

MTE-40017 Cell Biomechanics 34

MTE-40018 Human Physiology and Anatomy 35

MTE-40019 Trace Gas Analysis in Biomedicine 37

MTE-40020 Stem Cell Therapy: Enabling Technology 38

MTE-40021 Cell and Tissue Engineering 39

MTE-40014 Seminar Programme 40

Guidelines for the Research Project 42

Appendix A Advice on the avoidance of plagiarism 43

Appendix B University policy on plagiarism 46

Appendix B Guidelines for visual aids 47

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GENERAL INFORMATION ON COURSE AND UNIVERSITYPROCEDURES

Disclaimer:The information in this Handbook is as accurate and up-to-date as we can make it. It

does not, however, replace the entries in the University Prospectus and Calendar, whichare authoritative statements. In case of conflict, university regulations take priority. Thestatements of departmental policy in this Handbook are made in good faith. It mayhowever be necessary from time to time to vary courses, procedures, and otherarrangements.

Course aims and objectives:The aims of the courses are to provide multi-disciplinary Masters level postgraduatetraining in biomedical engineering and cell and tissue engineering. These will involvebuilding on existing undergraduate knowledge in basic sciences to apply to clinicalapplications of bioengineering and cell and tissue engineering relevant to the healthcare

environment.

The overall objectives are To provide courses at a postgraduate level leading to professional careers inbiomedical engineering and cell and tissue engineering in a wide range of healthcareestablishments i.e. medical organisations, medical research institutions and NHS Trusthospitals, To provide an opportunity for in-depth research into specialist and novel areas ofbiomedical engineering and cell and tissue engineering To expose students to practical work in a hospital environment with hands-on

knowledge of patient care To introduce students to exciting new fields within biomedical and cell and tissueengineering such as cellular engineering and novel technologies for physiologicalmonitoring.

Course structure:The courses consist of compulsory modules supplemented by a choice of optionalmodules; the student must gain at least 120 credits from these. The third semester isdevoted to a research project and dissertation, which, if successfully completed, providesthe additional 60 credits required for graduation.

Teaching methods:The main method will be subject-centred lectures, supported by tutorials and practicalexercises. Collaborative learning and student-centred learning will also be adopted, sothere will be a substantial amount of group work and individual assignments. Studentsare also required to conduct independent study to a very large extent.

Procedures for submitting and returning work:Work should be submitted via the Course Administrator on or before the due date.Arrangements and timescale for assessment of work will be notified by the tutor.

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Methods of communication within the Department:If students experience difficulty in arranging a meeting with a member of the teachingstaff, help should be sought via the Administrator. Timetable changes and other urgentinformation will be posted daily on: http://www.keele.ac.uk/depts/stm/postgrad/mscnews.htm.If possible they will be communicated direct to students, who should ensure that theAdministrator has their email address, telephone number and a mobile phone number ifavailable.

External Examiner: Dr Richard Black, University of Liverpool

Course Directors:Biomedical Engineering: Dr Isaac LiuCell and Tissue Engineering: Professor Alicia El Haj

Module Leaders:

MTE-40002 Physiological Measurement and MedicalImaging

Dr Y WickramasingheDr Richard Gadd

MTE-40003 Medical Electronics and EquipmentManagement

Dr John Thompson

MTE-40020 Stem Cell Therapy: EnablingTechnologies

Professor Alicia El Haj

MTE-40012 Biomechanics Dr Jan-Herman Kuiper

MTE-40018

MTE-40016

Human Physiology and Anatomy

Molecular Techniques: Applications inTissue Engineering

Dr Suzanne Whiteman

Dr Stuart McBain

MTE-40005 Biosensors Dr John Thompson

MTE-40001 Biomedical Signal Processing Dr Ahmed Keramane

MTE-40006 Biomaterials Dr Ying YangDr Jon Dobson

MTE-40019 Trace Gas Analysis in Biomedicine Dr Tianshu Wang

MTE-40021 Cell and Tissue Engineering Dr Sarah Cartmell

MTE-40009 Healthcare Technology Assessment Dr John Thompson

MTE-40007 Orthopaedics and Rehabilitation Dr Aziz Rahmatalla

MTE-40017 Cell Biomechanics Dr Isaac Liu

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Staff arrangements for seeing students:Students should make their own arrangements with individual members of staff to meetat a mutually convenient time. If difficulty is encountered with this, the CourseAdministrator will make an appointment on the students behalf.

Individual progress interviews:

The Head of Institute will arrange to see each student at least once during the academicyear. Additional interviews with the Head of Institute or Course Director can be arrangedas required.

Assessment Criteria: Used for assignments and examination papers0-19%: Unexaminable. Material submitted too little or of too poor quality to beexaminable properly.

20-29%: Clear fail. Little or no relevant empirical material. Poorly structured text, line ofargument unclear or unsubstantiated, material not related to the question or task (eg pure

description without any criticism or analysis).

30-39%: Fail. Some but inadequate empirical material, failure of much of the material toaddress the question/task, some illogicality of reasoning. Some evidence that thestudent has understood main elements in the question, but expresses himself or herselfbadly.

40-49%: Marginal fail. Some factual evidence. Knowledge of some landmark texts ordocuments. Coherent reasoning and some analysis which goes beyond puredescription. Evidence that the question has been understood and interpreted correctly.No gross errors of fact or theoretical misunderstandings. Little critical insight.

50% is the pass mark for Masters level work.

50-59%: Competent pass. Clear, well expressed arguments. Analytical reasoning aswell as accurate description. Good use of sources, including relevant literature.

60-69%: Strong pass. Good analytical and theoretical insights. Well structured andwell written answers. Evidence of some original thinking in collection and analysis ofmaterial. Relevant examples and illustrations of key themes.

70-79%: Distinction. Critical, self-critical and balanced text. Well presented and clearly

expressed arguments. New perspectives on key themes. Evidence of extensive readingand research. Very good use of different data sources. Original arguments.

80%+: As above, in under-researched field or with an original line of argument.Publishable in a learned journal or book as it stands or with minor amendments.

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The Universitys Codes of PracticePlease see:http://www.keele.ac.uk/depts/aa/regulationshandbook/section5.htm

Academic Regulations:Please see:

http://www.keele.ac.uk/depts/aa/regulationshandbook/reg2a.htm

Procedures when students fail assessments:Students will be allowed to retake the examination for failed modules during the latterpart of the third semester; in this case, University regulations do not permit the award of amark exceeding 50%. No further attempts are permitted except where an appealagainst the decision of the Examining Board is appropriate.(http://www.keele.ac.uk/depts/aa/regulationshandbook/reg2a.htm - satiswork)

Plagiarism:A statement of university policy on plagiarism can be found at:http://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htm#conductexamsIt is also printed as an annex to this Handbook. See also:http://www.keele.ac.uk/depts/aa/regulationshandbook/plagiarism&collusion.htm

Advice on the avoidance of plagiarism is at:http://www.keele.ac.uk/depts/aa/regulationshandbook/plagiarism.htmIt is also printed as an Annex to this Handbook.

Assessment procedures:A statement of the Universitys assessment procedures, General Regulations forUniversity Examinations and Assessments, can be found at:http://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htm

Academic warnings:A statement of university procedures for issuing academic warnings can be found at:http://www.keele.ac.uk/depts/aa/regulationshandbook/warnings.htm

Departmental complaints procedures:Students should arrange to discuss the difficulty informally with the Course Director in thefirst instance.

University complaints and appeals procedure:A statement of the university complaints procedure can be found at:http://www.keele.ac.uk/depts/aa/regulationshandbook/reg26.htm#top

The university appeals procedure is available at:http://www.keele.ac.uk/depts/aa/regulationshandbook/reg7.htm#top

Availability for vivas:Students are not expected to undertake a viva routinely. They should be available forexamination by viva at the end of the course in the event of a borderline result.

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http://www.keele.ac.uk/depts/aa/regulationshandbook/section5.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg2a.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg2a.htm#satisworkhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htm#conductexamshttp://www.keele.ac.uk/depts/aa/regulationshandbook/plagiarism&collusion.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/plagiarism.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/warnings.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg26.htm#tophttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg7.htm#tophttp://www.keele.ac.uk/depts/aa/regulationshandbook/section5.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg2a.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg2a.htm#satisworkhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htm#conductexamshttp://www.keele.ac.uk/depts/aa/regulationshandbook/plagiarism&collusion.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/plagiarism.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/warnings.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg26.htm#tophttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg7.htm#top


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Attendance requirements:Attendance at lectures and tutorials, including the Seminar Programme, is compulsory.Permission for brief absence may be sought from the appropriate tutor. A statement ofprocedures in the case of absence for illness and other good cause can be found at:http://www.keele.ac.uk/depts/aa/regulationshandbook/reg10.htm andhttp://www.keele.ac.uk/depts/aa/regulationshandbook/illness.htm

Disability:A statement of University policy on disability can be found at:http://www.keele.ac.uk/depts/aa/disabilityservices/statement/disability.htm

Student records:Records of students marks, copies of assignments and examination scripts are held inthe Administrative Office, as are completed application forms and copies of anycorrespondence with the student.

Sources of help and advice:There is a considerable amount of information at:http://www.keele.ac.uk/depts/aa/regulationshandbook/section3.htm.

In cases where this is insufficient, students should feel free to speak in confidence to amember of the teaching staff or the Administrator, who will make every effort to assist.

Evaluation and staff-student liaison:Each student is issued at the end of every module with an anonymous evaluation formfor the module. It is very helpful if these can be completed as fully as possible andreturned to the Administrator for distribution to the appropriate staff members. Concernsabout the course may be discussed informally with tutors.

Publication of results:Results of examinations for each module will be made known to students two monthsafter the examination. Final recommendations are made to the University in time to meetthe deadline for graduation ceremonies in line with the requirements of the Examinationsand Records Department, and results notified to students via the University.

Provision of references:Students must ask the staff member concerned before supplying his or her name as areferee. If no such request is made, it cannot be guaranteed that a reference will besupplied.

Safety regulations:

Students will be required to attend Health and Safety sessions as specified from time totime and to follow procedures as specified by the School of Medicine, and to undertakeany specialist training appropriate to their practical work during the course. Protectiveequipment and clothing must be used as instructed and all relevant safety protocolsobserved.

Web site information:http://www.keele.ac.uk/research/istm/MSCBIO.htm

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http://www.keele.ac.uk/depts/aa/regulationshandbook/reg10.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/illness.htmhttp://www.keele.ac.uk/depts/aa/disabilityservices/statement/disability.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/section3.htmhttp://www.keele.ac.uk/research/istm/MSCBIO.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg10.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/illness.htmhttp://www.keele.ac.uk/depts/aa/disabilityservices/statement/disability.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/section3.htmhttp://www.keele.ac.uk/research/istm/MSCBIO.htm


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CONTACT NUMBERS FOR MODULE TUTORS AND LECTURERS

Course Directors:Biomedical Engineering: Dr Isaac Liu (55)4600Cell and Tissue Engineering: Professor Alicia El Haj (55)4605

MTE-40002: Physiological measurement and Medical Imaging

Dr Y Wickramasinghe Clinical Technology Services (55)2190Dr Richard Gadd Nuclear Medicine (55)5137

MTE-40003: Medical Electronics and Equipment ManagementDr John Thompson 01543 492934Mr Dave Sargeant Clinical Technology Services (55)2562

MTE-40020: Stem Cell Therapy: Enabling TechniquesProfessor Alicia El Haj ISTM (55)4605

MTE-40012: BiomechanicsDr Jan-Herman Kuiper RJAH Oswestry 01691 404581

MTE-40018: Anatomy and PhysiologyDr Suzanne Whiteman ISTM (55)5452

MTE-40005: BiosensorsDr John Thompson 01543 492934

MTE-40016: Molecular TechniquesDr Stuart McBain ISTM (55)5312

MTE-40001: Biomedical Signal Processing and Modelling (55)5072Dr Ahmed Keramane ISTM

MTE-40006: BiomaterialsDr Ying Yang ISTM (55)4606Dr Jon Dobson ISTM (55)5639

MTE-400019: Trace Gas Analysis in BiomedicineDr Tianshu Wang ISTM (55)5199

MTE-40021: Cell and Tissue EngineeringDr Sarah Cartmell ISTM (55)5072

MTE-40009: Healthcare Technology AssessmentDr John Thompson 01543 492934

MTE-40007:Orthopaedics and RehabilitationDr Aziz Rahmatalla New Orthopaedic Development (55)2698

MTE-40017: Cell BiomechanicsDr Isaac Liu ISTM (55)4600

External Examiner: Dr Richard Black, University of Liverpool

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NORTHSTAFFORDSHIREHOSPITAL

NORTHSTAFFORDSHIRE

HOSPITAL


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MSc in Biomedical Engineering

COURSE REGULATIONS

These regulations supplement the relevant University Academic Regulations which areto be found on the University Web-site and in the University Calendar. In the eventof a contradiction or other discrepancy between these regulations and UniversityAcademic Regulations, the University Academic Regulations shall be authoritative,unless approval has been given by Senate for a variation from the UniversityAcademic Regulations.

1. Structure of the courseFirst Semester:

10

Physiological Measurement and Medical Imaging(Compulsory 20 credits)

Medical Electronics and Equipment Management(Compulsory 20 credits)

Molecular Techniques(Elective 10 credits)

Physiology and Anatomy(Compulsory * - 10 credits)

Stem Cell Therapy 1

(Elective 10 credits)

Biosensors(Elective - 10 credits)

SeminarProgramme(Com

pulsory20credits)

Biomechanics(Elective 20 credits)

Second semester:

Biomedical Signal ProcessingCom ulsor 20 credits

Biomaterials(Elective 20 credits)

Healthcare Tech Assessment(Elective 10 credits)

Cell and Tissue Engineering(Elective 20 credits)

Cell Biomechanics(Elective 10 credits)

Orthopaedics & Rehabilitation(Elective 10 credits)

Research project(Compulsory 60 credits)

Third semester:

Trace Gas Analysis(Elective 10 credits)

* See 5 below1 Prerequisite for MTE-40021 unless previous knowledge can be demonstrated


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2 Modules required for the purposes of professional exemption:None

3 Entrance requirements:Applicants are expected to have, or to anticipate receiving, at least the equivalent of a firstor second class degree from a UK university in a relevant subject; appropriate workexperience can be taken into account at the Universitys discretion.

Where English is not the first language, applicants must have an acceptable Englishqualification, as defined in the Graduate Prospectus.

4 Requirements for admission with advanced standing:Not applicable.

5 Requirements for approving module exemptions:Not applicable

6 Attendance requirements:Attendance is compulsory for modules in which students intend to be examined. They are

welcome to attend other lectures and tutorials in which they have an interest but in whichthey do not intend to take an examination.

7 Regulations governing fieldwork, placements or exchange periods:Not applicable.

8 Assessment regulations:Where modules have more than one form of assessment, it is not necessary to achieve apass mark on each element, so long as an overall mark of 50% is attained.

The aggregated mark for the course is calculated by an average of the marks for eachmodule and for the research project.

9 Regulations on the form and submission of coursework:Dates for submission of coursework are given by tutors, and must be adhered to unlessan extension is granted by the tutor or medical evidence can be provided.

The research dissertation is to be submitted by 14 September following the year of entryto the course. An extension until 31 December can be granted by the Course Director.

Any student requiring an extension beyond that date must supply evidence for submissionto the Aegrotat Committee.

10 Distinction award:The course has been approved as offering a Distinction award where students haveachieved an average mark of 70% and have attained a minimum mark of 70% for theresearch dissertation.

11 and 12: Deviation from University Academic Regulations and any other regulatorymatters:Not applicable.

The extension of the time limit for this course to five years when completed on a part-time ormodular basis was agreed by the Faculty of Health Course Development Sub-Committee on

10 September 2004.

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COURSE STRUCTURE AND CONTENT

These taught masters courses require satisfactory completion of at least 180 M levelcredits, made up of 120 credits from taught modules (80 credits core and compulsory, 40credits options) plus a project and dissertation for 60 credits. The module structure is set

out below.

Project dissertation (60 credits)

Research project and final dissertation of 15,000-20,000 words. This is an opportunityfor students to undertake laboratory based research in their chosen topic and shoulddemonstrate their understanding of the field via applications in healthcare.

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A Guide for Studying

Lectures

The most permanent record of any lecture course will be your notes. It is essential that theyshould be as clear as possible and arranged so that you can easily locate the information

within them. Acquiring the skill of making good lecture notes is essentially a matter ofcommon sense and practice. However, there are a few simple ways of making the processeasier:

i Arrive at the lecture in good time, and make sure that you have all the books, notesand equipment which you are likely to need;

ii Number the pages;iii Leave space to annotate your notes when you re-read them;iv Make sure that your notes are accurate.

It is always difficult to listen to the lecturer, read what is being written, attempt to understand

the material and make your own notes simultaneously. This needs hard work andconcentration during the lecture. The skill will develop with practice, but you should ensurethat you write down at leasteverything that the lecturer writes, unless written handouts areprovided. Dont worry if you do not understand everything immediately as it is presented inthe lecture; take as many notes as possible and ask your lecturer, your tutor or anotherstudent to explain as soon as possible. Do not be afraid to ask questions during or after alecture, or to query if you think the lecturer has made a mistake.

Read through your notes as soon as possible after the lecture, and annotate them ifnecessary in such a way that you will be able to understand them later. If you find that youcannot understand any part of your notes, check the information in the library, talk to other

students or raise the matter in your tutorials, or discuss the problem with your lecturer.

Tutorials

The format of these will vary according to the module. In general terms you should:

Make sure that you have brought any books or materials with you as instructedbeforehand by the tutor;

Prepare for the session by doing any reading or set work as recommended; Involve yourself fully by raising any questions and suggestions which you may have.

Set work

During the course you will have to complete a number of essays and projects which will formpart of your assessment. It is important that you organise your time so that you can submitthem promptly. If you need help with the work, or if you find that you will not be able tocomplete it by the deadline, make an appointment as soon as possible with the Module Tutorto discuss your problem dont wait until you are in serious difficulty. When you keep theappointment, make a list beforehand of any issues which you need to raise.

Theprovisional schedule for written work is below:

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The provisional schedule for written work is below:

Module Semester First/second half

Type of assignment % of totalmark

Exam %

MTE-40002 1 Both All assessment by

examination

100

MTE-40003 1 Both Coursework 60 40

MTE-40012 1 Both Paper based on practical may be taken intoaccount in the event of aborderline examinationresult.

100

MTE-40018 1 Both Coursework 20 80MTE-40016 1 First Coursework 10 90MTE-40020 1 Second Practical report

Oral presentation

10 1

5 185 1

MTE-40019 1 Second EssayExercise

35 2

15 250 2

MTE-40005 1 Second Coursework 50 50MTE-40001 2 Both Laboratory course work 30 70MTE-40006 2 Both All assessment by

examination100

MTE-40021 2 Both Practical write-up 35 3 65 3

MTE-40017 2 First EssayExercise

3015

55(passmark 30)*

MTE-40009 2 Second Essay 40 60MTE-40007 2 Second All assessment by

examination100

MTE-40014 Both Both Assessment bydissertation (5000 words)

100

* Please note that there is a pass mark of 30% for the examination in MTE-40017. In all othermodules, with the exception of those defined below, students are required to attain an overallmark of 50%, without a requirement to attain a minimum mark in any element of assessment.

1 The pass mark in each assessment is 50%. In the event of failure in any assessment, the

module mark will be capped at 50% at a second attempt. Only failed elements will need to berepeated.

2 The pass mark is 40% for the essay and the exercise, 50% for the examination. In the event offailure in any assessment, the module mark will be capped at 50% at a second attempt. Onlyfailed elements will need to be repeated.

1 The pass mark in each assessment is 50%. In the event of failure in either assessment,the module mark will be capped at 50% at a second attempt. Only failed elements willneed to be repeated.

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TIMETABLES

Please note:

In all timetables, PGM signifies Seminar Room 1, Postgraduate Medicine. Otherlocations are described in full.

All details provided for the Second half of the 1st Semester are provisional.

Because of clinical and other commitments of lecturers, it may on occasion be necessaryto rearrange lectures. You will be notified by email if this is the case.

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Time

INDUCTION

MTE-40014: S e m i n a r P r o g r a m m e (C)

EasterVacationandExams

MTE-40015ResearchProject (C)

MTE-40002: Physiological Measurementsand Medical Imaging (C/BE)

MTE-40003: Medical Electronics andEquipment Management (C/BE)

MTE-40012: Biomechanics (C/CE) (E/BE)

ChristmasVacationandEx

ams

MTE-40001: Biomedical Signal Processing(C/BE) (E/CE)

MTE-40006: Biomaterials (C/CE) (E/BE) MTE-40021: Cell and Tissue Engineering

(C/CE) (E/BE)

MTE-40018:Physiology and

Anatomy (C/BE)(E/CE)

MTE-40016:

MolecularTechniques (E)

MTE-40005:Biosensors (E)

MTE-40019: TraceGas Analysis inBiomedicine (E)

MTE-40020: StemCell Therapy:EnablingTechnologies (E)

MTE-40017:Cell Biomechanics(E)

MTE-40009:HealthcareTechnology

Assessment (E) MTE-40007:

Orthopaedics andRehabilitation (E)

Timetable for MSc in Biomedical Engineering and MSc in Cell and Tissue Engineering

(C): Compulsory module for both courses

(E): Elective module for both courses

(C/BE): Compulsory for Biomedical Engineering(E/BE): Elective for Biomedical Engineering(C/CE): Compulsory for Cellular Engineering(E/CE): Elective for Cellular Engineering

SEMESTER 1 SEMESTER 2 SEMESTER 3

Full Semester courses: 20 creditsHalf Semester courses: 10 creditsExcept as indicated

2006-2007 (Provisional)

C: Compulsory CE: Cell and Tissue EngineeringE: Elective BE: Biomedical Engineering

25.9.06

2.10.06

8.12.06

15.1.07

23.3.07

1.5.07

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T I M E T A B L E D A Y B Y D A Y

FIRST SEMESTER

October 2006WEEK 1

Mon 2 MTE-40018 PGM 9.30-11.30 amTues 3 MTE-40002 PGM 9.30-12Wed 4 MTE-40003 PGM 10-12.30Thurs 5 MTE-40012 PGM 10.30-1Friday 6 MTE-40016 (2nd Semester) PGM 10-12.30WEEK 2

Mon 9 MTE-40018 PGM 10-12Tues 10 MTE-40002 PGM 9.30-12

Wed 11 MTE-40003 PGM 10-12.30

Thurs 12 MTE-40012 PGM 10.30-1Fri 13 MTE-40016 (2nd Semester)

MTE-40018 Medical School, Keele10-12.303-5 pm

WEEK 3

Mon 16 MTE-40018 Room CBA1.070Chancellors Building, KeeleCampus.

9-10 am

Tues 17 MTE-40002MTE-40003

PGMPGM

9.30-122-4 pm

Wed 18 Seminar: Prof Jon Dobson Lecture Theatre PCS 1.30 pmThurs 19 MTE-40012 PGM 10.30-1Fri 20 MTE-40016 (2nd Semester) PGM 10-12.30WEEK 4

Mon 23 MTE-40018 PGM 10.30-12.30

Tues 24 MTE-40002Stats workshop

PGM 9.30-121.30-4.30

Wed 25 MTE-40003Seminar: Dr Malcolm Clench

PGM

PGM (seminar room 1)

10-12.30

2.00 pmThurs 26 MTE-40012 PGM 10.30-1

Friday 27 MTE-40016 (2nd Semester) PGM 10-12.30WEEK 5

Mon 30 MTE-40018MTE-40002

PGMPGM

9-10 am2-3 pm


PGM 9.30-121.30-4.30

November 2006

Wed 1Thurs 2Fri 3 MTE-40012 PGM 10-12.30

C/MSc Course/Biomedical Engineering/Cell & Tissue Engineering 2006/2007


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MTE-40018 Medical School, Keele 3-5 pmWEEK 6 - November 2006

Mon 6 MTE-40018MTE-40005 (Cancelled)

Mackay Inst, KeelePGM

10-122-5


PGM 9.30-121.30-4.30

Wed 8 MTE-10018MTE-40003Seminar: Dr David dePomerai

PGMPGMPGM (seminar room 1)

9-10 am11-12

2.00 pmThurs 9 MTE-40012 (Cancelled)

MTE-40020 (Cancelled)PGMPGM

10.30-12-4

Fri 10 MTE-40012MTE-40005

PGMPGM

10-30-1.00 pm2-5

WEEK 7

Mon 13 MTE-40020

MTE-40020MTE-40020

PGM

PGMPractical

9.30-11.30 am

1-2 pm2 pmTues 14 MTE-40002

MTE-40005PGMPGM

9.30 12.00 pm2-5 pm

Wed 15 MTE-40003Stats workshop (Cancelled)

PGM 10.30-12.301.30-4.30

Thurs 16 MTE-40012MTE-40020

PGMPGM

10.30-12-4 pm

Fri 17 MTE-40002MTE-40018

PGMMedical School, Keele

9.30 11.303-5 pm

WEEK 8

Mon 20 MTE-40002MTE-40002

PGMNeurology & ClinicalNeuro Physiology Bld, NSRI

9.30-10.30

11.00 amTues 21 MTE-40002

MTE-40020PGMPractical 1

9.30 11.302-5

Wed 22 MTE-40003 (Cancelled)Seminar: Prof Robert Brown

PGMLecture Theatre PCS

10-12.301.30 pm

Thurs 23 MTE-40002MTE-40012MTE-40020

PGMPGMPGM

9.30-10.3010.30-1.003-4 pm

Fri 24 Stats workshop (Cancelled)MTE-40020 PGM

9.30-12.302-4.30

WEEK 9Mon 27 MTE-40002 (Cancelled)

MTE-40003 (LB1 & LB2)PGM

PGM

9.30-10.30

2-4 pmTues 28 MTE-40002

MTE-40002PGMPGM

11-122-4.30

Wed 29 MTE-40003 (TA)Seminar: Prof Kevin Brindle

PGMPGM (seminar room 1)

10-122.00 pm

Thurs 30 MTE-40012Practical at Oswestry

PGM 10.30-1

December 2006:

Fri 1 MTE-40003 (LB3/LB7)MTE-40020

PGMPGM Ethics

10-12.303-4

MTE-40012

Practicalwo

rkat

Oswestry

tobe

arran

ged

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WEEK 10 - December 2006

Mon 4 MTE-40020MTE-40020

RegulationPractical 2 (Rescheduled to14/12/06)

10-122-5 pm

Tues 5 MTE-40002 (to be confirmed)MTE-40002

PGMPGM

9.30-122-3

Wed 6 MTE-40003 (TB)MTE-40003 (LB10)Seminar: Dr Rodrigo QuianQuiroga

PGMPGMPGM (seminar room 1)

10-1212-1 pm

1.30 pmThurs 7 MTE-40012

MTE-40020PGMPGM

10.30-1.002-3 pm

Fri 8 MTE-40003 (LB8 & LB9) PGM 2-4 pm

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MTE-40001: Biomedical signal processing and modelling

20 Lecture hours, 3 Tutorial hours, 8 Practical hours, 20 Credits

Module tutor:Dr Ahmed Keramane

Prerequisite:The prerequisite for this course is a degree in an engineering or physical science based subject.

Objective:

In view of recent developments in the biomedical engineering field, the modern day graduate training issues in Bioengineering revolve aroundcomputing technology and methods of processing biological signals, both for imaging and non imaging applications. The objective of thismodule is to let student gain the understanding of:1. The techniques involved in biomedical signal processing2. How to handle the recorded data from different medical instruments by the use of appropriate signal processing technique.3. System modelling and data analysis.4. Statistical properties of signals.5. Applications of mathematical techniques.

Lecture Schedule: Monday mornings from 15 January to 19 March 2007: 9.30 12 am.

BSP/L1 Basic terminology and regressionBSP/L2 Time domain processing for signalsBSP/L3 Fourier seriesBSP/L4 Fourier transformationsBSP/L5 Practicals and MatlabBSP/L6 Practicals and MatlabBSP/L7 Fourier transform propertiesBSP/L8 Fourier transform propertiesBSP/L9 Discrete Fourier transform

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BSP/L10 Discrete Fourier transformBSP/L11 Computer experimentsBSP/L12 Computer experimentsBSP/L13 Convolution and correlationBSP/L14 Power spectrum and applicationsBSP/L15 Signal filteringBSP/L16 Signal filteringBSP/L17 Signal filteringBSP/L18 Computer experimentsBSP/L19 Computer experiments

BSP/L20 Overview of the course

Assessment:The course will be assessed by laboratory course work (30%) and end of module written exam (70%)

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MTE-40002: Physiological measurement and medical imaging

Physiological Measurement

Module co-ordinator: Dr. Y. Wickramasinghe

Objective:To develop the students understanding of why physiological processes of humans are measured/monitored and to introduce differentphysiological measurement and therapy techniques.

Prerequisite:A prerequisite for this module is an undergraduate course completion and pass in human physiology and anatomy. If this is not available thestudent will be required to attend the course on Physiology and Anatomy for Bioengineers prior to attending this course. Basic knowledge inPhysics or Electronics is required to understand the measurement principles.

Indicative content:This module will cover transducers used in physiological measurement, invasive and non-invasive techniques of measurement of manyphysiological parameters such as: partial pressure of O2 and CO2, oxygen saturation, blood pressure, blood flow and some electrophysiologicalsignals (EEG, ECG, EMG). The course will also cover renal dialysis, pacemakers and intensive care monitoring.

Lecture and tutorial outline:1. Multi-parameter physiological measurements DE PGM 30/10 2-3 pm

2. Introduction to physiological measurement YW PGM 31/10 9.30-10.30 am

3. Transducers YW PGM 31/10 11-12 am

4. Audiology 1 MH PGM 7/11 9.30-10.30

5. Audiology 2 MH PGM 7/11 11-12 am

6. Oximetry YW PGM 14/11 9.30-10.30 am

7. Optical techniques YW PGM 14/11 11-12 am

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8. Optical techniques Tutorial 1 YW PGM 17/11 9.30-10.30 am

9. Fetal monitoring YW PGM 20/11 9.30-10.30 am

10.

EEG measurements JH Neurology & ClinicalNeuro Physiology Bld, NSRI

20/11 2 pm

11.

Blood flow measurements (Cancelled) YW PGM 21/11 11-12 am

12.

Measurement of pressure Tutorial 2 (Cancelled) YW PGM 27/11 9.30-10.30 am

13.

ECG/pacemakers/defibrillators PM PGM 28/11 11-12 am

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14 Mass spectroscopy in medicine 1 TW PGM 28/11 }15 Mass spectroscopy in medicine 2 TW PGM 28/11 } 2-4.30 pm16 Renal dialysis technology JM PGM 5/12 2-3

Revision and Tutorial 3 YW PGM 5/12 9.30-12 am

Lecturers:YW Dr. Yapa Wickramasinghe PM Phil MullinDE Mr Dave Evans JM John MooreTW Dr Tianshu Wang JH Jackie HandleyMH Marianne Holt

Medical ImagingObjectives:Many imaging modalities are in use in hospitals today and newer techniques and applications are being evolved. This module will enable the student :1. To provide an understanding of the principles for the use of diagnostic imaging.2. To identify the roles of differing imaging techniques in the evaluation of diseases.3. To discuss the risks including radiation issues, associated with different imaging systems.

Lecture Schedule

1 X-Ray Imaging (General and Fluoroscopic) 3/10 9.30-10.30 am PGM JG2 X-Ray Imaging (Computerised Tomography and Digital) 3/10 11-12 am PGM CJK3 Magnetic Resonance Imaging 10/10 9.30-10.30 am PGM BE4 Magnetic Resonance Imaging 10/10 11-12 am PGM EP5 Radiation Protection 1710 9.30-10.30 am PGM RG6 Ultrasound 17/10 11-12 am PGM RG7 Nuclear Medicine 1 24/10 9.30-10.30 am PGM JE8 Nuclear Medicine 2 24/10 11-12 am PGM JE

Assessment:Written examination at the end of term.

The lecturers are from the Directorate of Medical Physics, North Staffordshire Hospital, and the School of Postgraduate Medicine, Keele University

JE Jonathan EatoughCJK Chris Koller RG Richard Gadd

JG Jenny GeorgeBE Ben EppsEP Esther Paisley

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MTE-40003: Medical Electronics and Equipment ManagementModule tutor: Dr John Thompson

ObjectiveTo enable the student to develop a postgraduate level of understanding of the instrumentation required to support medical applications.To define equipment safety and provide a knowledge of the practice of effective equipment management.

Lecture Schedule

Code Title Lecturer Location Date Duration Time

2005A MEDICAL INSTRUMENTATION

LA1 A model for a medical device JT PGM 4/10 1 hr 10-11 1LA2LA3

Fundamentals of transducersFundamentals of operational amplifiers

JTJT

PGMPGM

4/1011/10

1 hr1 hr

11.30-12.3010-11

23

LA4 Fundamentals and practical applications of signal processing JT PGM 11/10 1 hr 11.30-12.30 4LA5 Case study: the anaesthetic machine, part 1 JT PGM 17/10 1 hr 2-3 5LA6 Case study: the anaesthetic machine, part 2 JT PGM 17/10 1 hr 3-4 6

B TECHNOLOGY MANAGEMENTEssay Writing JT PGM 25/10 1 hr 10-11.00

LB4 Planned preventative maintenance (PPM), incidents, repairs,clinical support, replacement and disposal

DS PGM 8/11 1 hr 11-12 11

LB5 Training and the safe use of medical devices TBA PGM 15/11 1 hr 10.30-11.30 12LB6 Asset management and record keeping DS PGM 15/11 1 hr 11.30-12.30 13LB1 An overview of healthcare technology management JT PGM 27/11 1 hr 2-3 8

LB2 Project management JT PGM 27/11 1 hr 3-4 9TA Tutorial JT PGM 29/11 2 hrs 10-12 7LB3 Assessment, evaluation, feasibility studies, specification,

procurement, acceptance, installation and commissioningJT PGM 1/12 1 hr 10-11 10

LB7 Risk management JT PGM 1/12 1 hr 11-12 14TB Tutorial JT PGM 6/12 2 hrs 10-12 18LB10 Quality management systems DS PGM 6/12 1 hr 12-1 pm 17LB8 Reliability and maintainability JT PGM 8/12 1 hr 2-3 15LB9 Standards, regulations and professional bodies JT PGM 8/12 1 hr 3-4 16

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Lecturers:JT John Thompson DS Dave Sargeant

Assessment: This module will be assessed by coursework (60%) and final examination (40%)

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MTE-40005: Biosensors

Total: 10 hours

Module Leader: Dr John Thompson

Lecture Schedule

Chemical Sensor and Biosensor Technologies: JT PGM 6/11 2-5 pmThis introductory technology overview will cover some general principles of molecular sensor construction and uses. The topics

introduced will include:What is being sensed;The physical phases in which sensing may take place;Various sensing mechanisms (chemical, biochemical, biological etc);Types of transducer of the sensing mechanism used to create appropriate signals;Sensor applications (diagnostics, patient monitoring, food, environment etc);The various medical contexts of sensing (in vitro, ex vivo and in vivo);Problems of biocompatibility;Signal processing issues.

Electrochemical Transduction:Potentiometric, amperometric, coulometric and conductometric measurements, reference electrodes, ion selective and redoxelectrodes, ion selective field effect transistors, etc.

Optical Transduction: JT PGM 10/11 2-5 pmUsing refraction phenomena; surface plasmon resistance and fibre optic evanescent wave sensors. Spectral sensing using opticalabsorption, fluorescence and phosphorescence, bioluminescence.

Other Topics in Transduction and Sensor Design:Thermal/calorimetric methods, surface acoustic wave and piezoelectric methods. Electronic noses. Biocompatibility, includingbiofouling and biofilm formation, haemocompatibility, tissue biocompatibility.

Biosensing Mechanisms 1: JT PGM 14/11 2-5 pmUsing enzymes directly to sense molecules. Some principles of enzyme behaviour, including enzyme-substrate interactions, co-

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enzymes, enzyme kinetics, using mediators in coupling enzyme reactions to transducers, enzymes as labels for other biochemicalreactions. Mathematical modelling of enzyme reactions.

Biosensing Mechanisms 2:Using immunological rections for sensing. Introduction to the range of reactions: antibody-antigen interactions in immunoassays,other useful reactions from the immune system. Kinetic and equilibrium assays.

Biosensing Mechanisms 3: JT PGM 21/11 2-5 pmNucleic acid based sensing: DNA and RNA chip technologies. Cell and organism based sensors: microbial sensors, use of otherbioreceptors and organisms.

Sensor Fabrication Technologies:Macroscopic sensors, microsensors, nanoscale sensors and lab-on-a-chip technologies. Adapting electronic fabrication, screen-printing, ink-jet and other mass production technologies, using CAD-based prototyping. Dealing with problems in mass-productionof sensors, including QA/QC.

Biosensor Performance: JT PGM 1/12 2-5 pmTheoretical aspects (diffusive and convective mass transport). Experimental design of performance assessment and optimisation:laboratory, pre-clinical and clinical aspects.

Case Study and Tutorial

Assessment: Coursework 50%, examination 50%

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MTE-40006: Biomaterials

Module tutor: Dr Y Yang, Professor J Dobson

20 lecture hours

Objectives:

1 To introduce the basic knowledge of biomaterials;2 To understand the interaction between physiological components and biomaterials;

3 To acquire the applications and biocompatible issue of biomaterials1 Introduction (1 hour)1.1 Definition and division of biomaterials1.2 History and recent development of biomaterials1.3 Subjects integral to biomaterials:

1.3.1 Toxicology1.3.2 Biocompatibil ity1.3.3 Mechanical and performance requirements

1.4 Applications of biomaterials in clinics1.5 Procedure to develop an application of biomaterials in clinical field

2 Classes of biomaterials used in medicine (2 hours)2.1 General introduction2.2 Metals and their alloys:

2.2.1 Molecular structure and physical properties2.2.2 Processing and applications

2.3 Ceramic and glass:2.3.1 Molecular structure and physical properties2.3.2 Processing and applications

2.4 Polymers:2.4.1 Molecular structures and physical properties2.4.2 Processing and applications

2.5 Natural materials

3 Biological reactions to biomaterials and their evaluation (2 hours)3.1 General introduction3.2 Macro-phenomena:

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3.2.1 Inflammation and wound healing3.2.2 Foreign body response

3.3 Micro-phenomena:3.3.1 The structure and properties of proteins and their adsorption to foreign

surfaces3.3.2 The surface structure and interaction of cells with biomaterials3.3.3 Blood coagulation and blood-biomaterial interaction

4 Degradation of biomaterials in the biological environment (2 hours)4.1 Degradation of metal and ceramics4.2 Degradation of polymers4.3 Mechanical breakdown of biomaterials4.4 Applications of biodegradable polymers:

4.4.1 Short-term medical applications4.4.2 Temporary scaffold4.4.3 Temporary barr ier4.4.4 Commonly used degradable polymers

5 Improvement of biocompatibility in biomaterials (2 hours)5.1 Definit ion of biocompatibil ity

5.1.1 Bioinertia and biocompatibility5.1.2 Haemocompatibility

5.2 General techniques to improve surface properties of biomaterials5.2.1 Physical treatments5.2.2 Chemical treatments5.2.3 Mimicry of natural membrane

6 Applications of biomaterials in medicine (1 hour)6.1 General and routine appl ications6.2 Cardiovascular appl icat ions:

6.2.1 Heart valve6.2.2 Pacemaker 6.2.3 Cardiopulmonary bypass

6.3 Orthopaedic applications6.3.1 Orthopaedic fixation devices6.3.2 Bone nails, screws and plates

6.4 Dental implants6.5 Adhesives and sealants6.6 Drug delivery system

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6.7 Biosensors

7 Magnetic Biomaterials (10 hours)7.1 Introduction

7.1.1 What are magnetic materials?7.1.2 How are they used in biomedical applications?

7.2 Electricity and Magnetism An Overview7.2.1 Electrostatics7.2.2 Electromagnetism

7.3 Magnetism in Matter 7.3.1 The origin of magnetism in matter7.3.2 Types of magnetism in materials

7.4 Magnetic Materials in Biology and Medicine7.4.1 Endogenous magnetic materials7.4.2 Biocompatible synthetic magnetic materials

7.5 Interactions of Magnetic Biomaterials with Applied Fields7.5.1 Public Health implications7.5.2 MRI safety issues7.5.3 Biomedical appl icat ions

MagnetoimmunoassayMRI contrast enhancementDrug and gene delivery

Assessment:

This module will be assessed by examination.Lecture dates and times:Thursday mornings from 18 January to 22 March 2007, 9.30 12 am

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MTE-40007: Orthopaedics and Rehabilitation

Module tutor: Dr Aziz Rahmatalla

Objectives:Application of engineering principles to the human body to enable a higher quality of life is one important element in bio engineering. Themodule will consider current research in the field of Orthopaedics and Rehabilitation.

Lecture Schedule: Provisionally Tuesday mornings from 20 February to 20 March 2007: 9.30 12 am

1 Introduction to skeleton and joints2 Posture and locomotion3 Material in orthopaedics4 Spinal instrumentation and spinal biomechanics5 Spasticity management and alteration in gait6 Mobility and limb prosthesis7 Applied anatomy and biomechanics of joints8 Role of robotics and computer aided surgery9 Influence of fixation on the healing process

10 External fracture fixation systems11 Joint replacement and implants

Tutorial

Lecturers:

JD John DoveCWJ Charles Wynn JonesRS Rajiv Singh

AW Tony Ward

PBMT Peter ThomasIM Ian Moorcroft

AR Aziz Rahmatalla

Assessment: By examination

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MTE-40009: Health Technology Assessment

Module Leader: Dr John Thompson

Prerequisites: No prerequisites for this course

ObjectiveThis module will provide students with the knowledge to: Acquire the necessary methodologies to assess and evaluate new technologies Understand cost/benefit factors and factors which provide a measure of the quality of life

Lectures will take place on Wednesday afternoons from 14 February to 21 March 2007

Title Date Venue Time1 Introduction to HTA Aims, Objectives, Methods And Stages 13/2 PGM 3 pm2 Clinical Governance and HTA 13/2 PGM 4 pm3 Clinical Audit 20/2 PGM 2 pm4 Economic Evaluation in HTA, Part 1 20/2 PGM 3 pm5 Economic Evaluation in HTA, Part 2 20/2 PGM 4 pm6 Assessing Clinical Measurement Technologies, Part 1 27/2 PGM 2 pm7 Assessing Clinical Measurement Technologies, Part 2 27/2 PGM 3 pm8 Randomised Controlled Trials of Therapeutic Technologies 6/3 PGM 2 pm9 Epidemiological Methods in HTA: Questionnaire Design 6/3 PGM 3 pm

10 Epidemiological Methods in HTA: Study Design and Analysis 13/3 PGM 2 pm11 Meta-analysis of Published Trials 13/3 PGM 3 pm12 Horizon Scanning and Technological Forecasting 20/3 PGM 2 pm

Tutorial 20/3 PGM 3-5 pm

Assessment: Essay 40%, examination 60%

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MTE-40012: BiomechanicsNumber of lecture hours: 22.5 plus one days practical work at Robert Jones and Agnes Hunt Orthopaedic Hospital, OswestryIn addition, the whole group will find a mutually agreeable time to have a weekly hour-long online discussion to help solving example problems.Lecturer: Dr. Jan-Herman Kuiper (Week Venue Content Tissue Method Book1 (5/10) PGM Lecture 10.30-1 Introduction, Force,

Moment/TorqueAnalytical modelling ON 1,2,3

2 (12/10) PGM Lecture 10.30-1 Static equilibrium, Free Body

Diagram

Whole body Analytical modelling ON 4,5

STM 13 (19/10) PGM Lecture 10.30-1 Stress/strain, elasticity

Bending/torsionBone Mechanical test

Strain gaugeON 6,7

4 (26/10) PGM Lecture 10.30-1 Mechanical properties of bone(stiffness, strength, fatigue)

Mechanical test, Strain gauge,Finite Elements

STM 4,5

5 (3/11) PGM Lecture 10.30-1 Two-phase material Cartilage Indentation test; Compressiontest; Fuji-film; Computermodelling

STM 7

6 (10/11) PGM Lecture 10.30-1 Viscoelasticity, Creep Tendon/Ligament

Cyclic testVideo-analysis

STM 8

7 (16/11) PGM Lecture 10.30-1 Simulation of processesDifferentiation/remodeling/healing

Bone,cartilage,fibrous

Animal experimentComputer modelling

STM 6/7/8

8 (?23/11) Oswestry * Practical Determine mechanical properties Bone Compression test9 (30/11) PGM Lecture 10.30-1 Bioactivity Muscle Tensile tests, electro-

stimulation, EMGFung 9

10 (7/12) PGM Lecture 10.30-1 Recap, old exams, questions etc

* Provisional dates

Core materialON: N zkaya, NM Nordin, Fundamentals of Biomechanics, Springer-Verlag, New York, 1999STM: R Bruce Martin, DB Burr, NA Sharkey, Skeletal Tissue Mechanics, Springer-Verlag, New York 1998Fung: YC Fung, Biomechanics, 2nd ed., Springer-Verlag, New York 1993

Assessment will be by a paper based on the practical and a final exam.


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MTE-40017: Cell Biomechanics

Module tutor: Dr Isaac Liu

Objectives:

1. To introduce the subject of cell biomechanics.2. To outline the interrelationships between mechanics and cell biology.

3. To identify the application of cell biomechanics in cell/tissue engineering and biomedical engineering.

Lecture Synopsis: Content Venue Time Date

1. Introduction PGM 17/1 9:30-10:302. Experimental methods (I) PGM 17/1 11-123. Experimental methods (II) PGM 24/1 9:30-10:304. Review of biomechanics PGM 24/1 11-125. Viscoelasticity of cell PGM 31/1 9:30-10:306. Mechanics of cell deformation (I) PGM 31/1 11-127. Mechanics of cell deformation (II) PGM 7/2 9:30-10:308. Cell-flow interaction PGM 7/2 11-129. Mechanics of cell adhesion (I) PGM 14/2 9:30-10:3010. Mechanics of cell adhesion (II) PGM 14/2 11-1211. Cell-substrate interaction (I) PGM 21/2 9:30-10:3012. Cell-substrate interaction (II) PGM 21/2 11-12

All the lectures will be given by Dr Isaac Liu.


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Assessment:This module will be assessed by essay (30%), exercise (15%) and examination (55%).


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MTE-40018: Human Physiology and Anatomy

Module Tutor: Dr Suzanne Whiteman

Prerequisites: This course is a prerequisite for attendance for all Biomedical Engineering students who have not provided evidence ofprevious attendance on a similar course at undergraduate level.

Objective:This is a review course on physiology and anatomy for bioengineers. It is often the case that the practising Bioengineer has a poor knowledge

about the Anatomy and Physiology of the human body. This module provides an outline understanding of the structure, function and physics ofthe human body, and introduces physical concepts applicable to medicine.

1 Respiratory 1Respiratory 2

SW PGM 2/10 9.30-11.30 am

2 Neurology 1 DF PGM 9/10 10-123 Neurology 2 DF 9/10

Anatomy practical:Introduction to

Anatomical SpecimensMuscular, Skeletal, Jointsystems

MM Medical School, Keele Campus 13/10 3-5 pm

4 Cardiovascular DC Room CBA1.070 Chancellors Building, KeeleCampus

16/10 9-11

5 Renal 1 SD PGM 23/10 10.30-12.306 Renal 2 SD 23/107 Musculo-skeletal 1 JM PGM 30/10 9-10 am

Anatomy practical:Cardiovascular andrespiratory systems


8 Immunology 1 TG Lecture Theatre CNS, Mackay Institute, LifeSciences, Keele Campus

6/11 10-129 Immunology 2 TG 6/11


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Musculo-skeletal 2 JM PGM 8/11 9-10 amAnatomy practical:Urinary/renal andnervous systems


Visits to Cardiothoracic Theatre (small groups, by arrangement)

Lecturers:

DC Dr Doug CorfieldSD Dr Simon DaviesDF Dr Dave FurnessTG Professor Trevor Greenhough

SW Dr Suzanne WhitemanMM Dr Mike MahonJM Jim Middleton

Assessment is by examination (80%) and essay (20%)


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MTE-40019: Trace Gas Analysis in Biomedicine

Module Tutor: Dr Tianshu Wang

Assessment: Unseen examination 50% (pass mark 50%); essay (2000 words) 35% (pass mark 40%); essay with three calculation problems15% (pass mark 40%). In the event of failure in any assessment, the module mark will be capped at 50% at a second attempt. Only failedelements will need to be repeated.

1 Analytical methods in trace gas analysis TW PGM 10/11 10-11 am2 Analytical methods in trace gas analysis TW PGM 10/11 11.30-12.303 Applications of trace gas analysis in medicine TW PGM 17/11 10-11 am4 Applications of trace gas analysis in medicine TW PGM 17/11 11.30-12.30

5 Applications of trace gas analysis in physiology TW PGM 24/11 10-11 am6 Applications of trace gas analysis in physiology TW PGM 24/11 11.30-12.307 Applications of trace gas analysis in cell biology TW PGM 1/12 10-11 am8 Applications of trace gas analysis in cell biology TW PGM 1/12 11.30-12.309 Biomarkers of cell, bacteria and diseases TW PGM 8/12 10-11 am

10 Biomarkers of cell, bacteria and diseases TW PGM 8/12 11.30-12.30


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MTE-40020: Stem Cell Therapy: Enabling Techniques

Module Tutor: Professor Alicia El Haj

This module is a prerequisite for the Cell and Tissue Engineering module unless previous knowledge can be demonstrated.

AEH: Professor Alicia El HajHS: Harpal SuraKH: Karen Hampson

SH: Steven HughesTE: Tracy EllisonGS: Dr Glyn Stacey

NF: Nick Forsyth

Practical: Isolation of mesenchymal stem cells from commercial bone marrow

Assessment: Unseen examination 85% (Pass mark 50%); Practical report 10% (Pass mark 50%); Oral presentation 5% (pass mark 50%). Inthe event of failure in any assessment, the module mark will be capped at 50% at a second attempt. Only failed elements will need to berepeated.

1 Introduction to stem cells AEH PGM 13/11 9.30-11.30 pm2 Embryonic stem cells NF PGM 13/11 1-2 pm

3 Cord blood derived stem cells NF PGM 16/11 2-3 pm4 Bone marrow derived adult stem cells NF PGM 16/11 3-4 pm

Practical Part 1 HS 21/11 2-5 pm5 Stem cell targeting AEH PGM 23/11 3-4 pm6 Control of differentiation (1) SH PGM 24/11 2-4.30 pm7 Control of differentiation (2) SH PGM8 Ethics TE PGM 1/12 3-4 pm9 Regulation GS PGM 4/12 10-12

Practical Part 2 H S 4/12 2-5 pm10 Tissue Specific Stem Cells NF PGM 7/12 2-3 pm


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MTE-40021: Cell and Tissue Engineering

Module tutor: Dr Sarah Cartmell

1 Introduction 1hr2 Cell culture techniques 1hr3 Cellular engineering mech forces 1hr4 Cellular engineering topography 1hr

5 Cellular engineering gene therapy 1hr6 Gene therapy clinical application 1hr7 Bone engineering 1hr8 Tendon/ligament engineering 1hr9 Cartilage engineering (visit to Oswestry and ACI introduction) 2hr10 Corneal engineering 1hr11 Liver engineering 1hr12 Neural engineering 1hr13 Skin engineering 1hr14 Vascular engineering 1hr15 Complex organ engineering 1hr16/17 TE construct monitoring and evaluation 2hr18 Bioreactor design 1hr19 Regenerative medicine the clinical side (tissue engineering old idea, new name) 1hr

Practical 2 afternoons (3hours each)

Assessment: Examination 65%, Practical write-up 35%. The pass mark is 50% for each assessment. In the event of failure in eitherassessment, the module mark will be capped at 50% at a second attempt. Only failed elements will need to be repeated.


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MTE-40014

SEMINAR PROGRAMME: Autumn 2007Institute Seminars (1:30pm start in Primary Care Sciences, 2 pm start in Postgraduate Medicine):

DATE NAME TITLE SUBJECT VENUE

Wed 18 October 2006 Professor Jon Dobson Professor of Biophysics andBiomedical Engineering,Keele University

Biological magnets:Nanomagnetics in Biologyand Medicine

Lecture Theatre, Primary CareSciences

Wed 25 October 2006 Dr Malcolm Clench Reader in MassSpectrometrySheffield Hallam University

Through a Glass Darkly Imaging Mass Spectrometryof Biological Surfaces

Seminar Room 1, PGM

Wed 1 November 2006 Dr Jon Cooper(Cancelled to berescheduled)

Professor of Bioelectronicsand BioengineeringUniversity of Glasgow

Title to be confirmed Seminar Room 1, PGM

Wed 8 November 2006 Dr David de Pomerai Associate Professor,School of BiologyUniversity of Nottingham

Microwaves and nematodes a cautionary tale

Seminar Room 1, PGM

Wed 22 November 2006 Professor RobertBrown

University of Glasgow Epigentic biomarkers andcancer chemotherapy


Wed 29 November 2006 Prof Kevin Brindle University of CambridgeCancer Research UK

Detecting tumour responsesto therapy using magneticresonance imaging andspectroscopy

Seminar Room 1, PGM

Wed 6 December 2006 Dr Rodrigo QuianQuiroga

Reader in Bioengineering,University of Leicester

Single neuron correlates ofconscious visual perceptionin humans

Seminar Room 1, PGM

Wed 13 December 2006 Dr Joanne Webster Reader ParasiteEpidemiology and Head of

The rat sat on the cat:Implications of Toxoplasma



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Research SurveillanceImperial College, London

gondii's ability to alter hostbehaviour

Wed 17 January 2007 Professor LaurenceYoung

Professor of Cancer BiologyUniversity of Birmingham

Novel anti-cancer therapies:From bench to bedside



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DATE NAME TITLE SUBJECT VENUE

Wed 28 February2007

Professor BruceCaterson

University of Cardiff Title to be confirmed Lecture Theatre, PrimaryCare Sciences

March (to be

confirmed)

Professor Sarah Dallas University of Illinois Title to be confirmed To be confirmed

Wed 25 April 2007 Professor DonnaDavies

University of Southampton Title to be confirmed Lecture Theatre, PrimaryCare Sciences

Wed 23 May 2007 Professor Corne Kors University of Sussex Title to be confirmed Lecture Theatre, PrimaryCare Sciences

Wed 6 June 2007 Professor QuentinPankhurst

UCL Title to be confirmed Lecture Theatre, PrimaryCare Sciences

Venues

PGM - Postgraduate Medicine, HartshillLecture Theatre, Primary Care Sciences, Medical School, Keele Campus


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MSc IN BIOMEDICAL ENGINEERINGMSc IN CELL and TISSUE ENGINEERING

Guidelines for Research Project

Objectives of the Project:o To demonstrate the students understanding of and ability to apply the taught

element of the MSc course;o To demonstrate the students ability to search and analyse the relevant literature;o To demonstrate the students ability to design, implement and evaluate

appropriate experimental processes.Deadlines:The deadline is 14 September 2007.Approval from the Course Director needs to be obtained for late submission, statingvalid reasons for the request.A case has to be made to the SCEACE Committee for submission to be delayed formore than four weeks (12 October 2007).

Marking criteria:40% of the final percentage will be awarded to the literature review (Chapter 1).The remaining 60% will be allocated to the experimental work and its description(55% for the written work and 5% for an oral presentation).

Structure of the thesis:o Title pageIncluding title of thesis, name, Institute address, telephone number, email.

o Acknowledgments

o Abstract

o IntroductionAims and objectives of the project. Brief statement of work undertaken. Reasonsfor choosing the project.

o Chapter OneReview: Review of the state-of-the-art techniques and knowledge in the field.

o Chapter TwoExperimental design and method. Statement of the method of pursuing thehypothesis, equipment used, set-up of the experimental procedure, scientificbasis for the project.

o Chapter ThreeResults.

o Chapter FourDiscussion. Discussion of the results obtained.

o Chapter FiveConclusions. A summary of the conclusions reached.

o References


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Appendix A: Advice on the avoidance of plagiarism

1. What is Plagiarism?

Plagiarism means the use of the ideas, words or findings of others withoutacknowledging them as such. In other words, to plagiarise is to give the impressionthat the student has written, thought or discovered something that he or she has in

fact borrowed from someone else without acknowledging this in an appropriatemanner.

It is an academic expectation that the ideas, words or findings of another person arenot used without acknowledgement. Students may certainly use the words, thoughtsor findings of others, but the original authors and sources must be acknowledged.Not to do so is academic dishonesty and a form of cheating.

The mark for written work in part reflects the student's understanding of the subject ofa piece of assessed work. If he or she has merely repeated the words of another, itis difficult to assess the student's understanding and so to award marks for it. It is,therefore, totally unacceptable for students to plagiarise in their written work. Anyonewho does so will have committed an unfair examination practice and will be subjectto strict University procedures and penalties.

2. Citation

Proper acknowledgement is termed "citation". There are several conventionsgoverning citation.

The examples given below relate to arts and social science subjects. The sameconventions apply to the sciences, especially when data sources or the results of

experimentation by others are being used.

The examples also relate to published work. It is equally unacceptable to quotewithout acknowledgement from an unpublished source (e.g. a thesis or the web).

The most blatant form of plagiarism is to repeat the words, phrases or sentences ofanother person, more or less verbatim. For example, the following passage appearson page 906 in volume 1 of the Literary History of the United States:

The major concerns of Dickinson's poetry.may be defined as the seasons andnature, death and a problematic afterlife, the kinds and phrases of love, and poetryas the divine art.

If this were to appear in an essay as follows, without citation, it would be plagiarism:

The chief subjects of Emily Dickinson's poetry include nature and the seasons, deathand the afterlife, the various types and stages of love, and poetry itself is a divine art.

However, if the authors are credited as follows the passage is acceptable:

Gibson and Williams suggest that the chief subjects of Emily Dickinson's poetryinclude mature, death, love and poetry as a divine art (1974, 1,906)

The reference in brackets refers to the source document which would appear in the

bibliography as:


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Gibson, W.M. and Williams, S.T. 1974. "Experiment in Poetry: Emily Dickinson andSidney Lanier in Literary History of the United States, ed. By Robert E. Spiller andothers, 4th edn, 2 vols, New York: Macmillan, 1, 899-916.

Citation by footnote is also acceptable. For example:

"Inequality of bargaining can arise either from the general structure and

circumstances of the market place, or from the individual personal circumstances ofone or both parties". (1)

(1) J R Peden, The Law of Unjust Contracts, 1982, p 39. at the foot of the page. Asabove, the work would also be cited in the bibliography.

If only part of a passage is being used, this should be indicated by replacing theomitted words with a short series of dots. For example:

"The common law doctrine of unconscionability is based upon certain elements ofjustice ... but it never sought to achieve distributive or commutative justice." (1)

(1) J R Peden, The Law of Unjust Contracts, 1982, p 3.

It may also be necessary to alter the words being quoted so as to fit them into thecontext in which the quotation is being used, or to overcome the problem that thequotation may not make sense when taken out of its own context. Omitted wordsshould be dealt with as above. Any words added should be enclosed in brackets. Forexample:

"This principle [sanctity of contracts] is closely associated with that of freedom ofcontract ..."(1)

If the exact words of another person are not being used, but there is reference to hisor her ideas, this should be acknowledged in a footnote referring to the author, thework, the reference if it is in a periodical, and to its page and introduced as follows:

As Professor Peden has argued, etc.

or

As Professor Peden in his work on unjust contracts has argued, etc.

Secondary Citation

It may be that the quotation has been found quoted in the work of someone else. Insuch cases the original source should be cited (which the author will have cited) andthe reference where it was found. For example, a footnote might read like this:

(1) Gwynne v Heaton (1778), 1 Bro C C 1, at p 9, 28 E R 949, at p 953 per LordThurlow L C, quoted by J R Peden, The Law of Unjust Contracts 1982, p 19.

3. Collusion

Collusion is another form of academic dishonesty (cheating). It is similar toplagiarism. It is accepted that students may well work together and exchange ideas.

Indeed, in some instances such co-operation, collaboration or team-working, isencouraged. However, if the collaboration results in pieces of work submitted by


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individual students as their own work but which are essentially the same or verysimilar, collaboration becomes collusion.

An extreme form of collusion is where someone other than the student undertakesthe piece of work on the student's behalf, and the student presents that piece of workas his or her own. Particular examples are the use of web essay banks or thirdparties who offer essay writing facilities.

Keele University Academic Regulations:http://www.keele.ac.uk/depts/aa/regulationshandbook/plagiarism.htm
http://www.keele.ac.uk/depts/aa/regulationshandbook/plagiarism.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/plagiarism.htm


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Appendix B: University policy on plagiarism

ALLEGATIONS OF CHEATING OR OTHER EXAMINATION MISCONDUCT TO BEDEALT WITH AT DEPARTMENTAL LEVEL

1. This policy is made under the terms Academic Regulation 8.

2. Examinations

Departments shall have no responsibility in respect of alleged misconduct inexaminations at any level. All such allegations shall be considered under the terms ofAcademic Regulation 8 12.

3. In-course assessment and dissertations

3.1 Heads of Department shall ensure that there is clear guidance available tostudents in the Course/Departmental Handbook concerning the avoidance ofplagiarism and collusion.

3.2 There shall be standard cover sheets for dissertations/ projects/extended essays

submitted for undergraduate and for postgraduate awards which shall include adeclaration that "no part of the work .... is a quotation from published or unpublishedsources, except where this has been clearly acknowledged as such by citation of thesource".

3.3 Before any allegation of plagiarism or collusion is made, the examiner should beable to demonstrate clearly the source of the plagiarism or the correlation betweentwo pieces of work where collusion is suspected.

The authority granted to Schools in dealing with cases of alleged plagiarism andcollusion is set out in Academic Regulation 8.12

Academic Regulations and Guidance for Students and Staff, Keele University

PLEASE EXAMINE REGULATION 8.12 CAREFULLY; PENALTIES FORPLAGIARISM ARE SEVERE. IF IN DOUBT, ASK YOUR TUTORS FOR ADVICE.
http://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htm#cheatinghttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htm#cheatinghttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htmhttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htm#cheatinghttp://www.keele.ac.uk/depts/aa/regulationshandbook/reg8.htm#cheating


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GUIDELINES FORVISUAL AIDS

Legibility

Your effort in producing your PowerPoint presentation will be wasted if your

audience cannot read it! So please pay particular attention to the following. Think of

the person seated in the back row of the auditorium!

Font size:

The minimum height of the smallest letters (including lower case) is 5 mm

Examples:

Use 24-point type for lettering done in ALL CAPITALS

and 32-point for lettering in

Capitals and Lowercase

Note Bigger sizes than this if you wish, but not smaller!

Typeface

Improve visibility by using a sans serif typeface such as ArialorUniversinstead of a serif typeface like Times.

Layout

Visual aids used in a presentation must be twice as simple and four times as bold as

those used in your written paper. You will need to eliminate all unnecessary details,

so the following approaches are recommended:

Round off numbers; cut decimal places

Use a scale along either the horizontal or vertical axis of a graph, bar chart, or

column chart instead of numbers at the end of the bars or columns

Substitute symbols for words - % is better than percent

Do not use footnotes; introduce the information as part of what you say if its

important enough to mention

Omit reference sources in visual aids

Omit lines that detract: avoid underlines, excessive grid rulings, unnecessary

outlines and company logos

Appendix C


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Colour

Use colour with purpose, not as decoration!

For example, colour can be used

To emphasise a trend line, a component, a row of data, a title;

To identify a recurring theme throughout the presentation (display related data in

the same colour);

To distinguish actual from projected, or one trend from another;

To symbolise the meaning of a word (losses in red, Go in green);

Use contrasting colours for example, bright yellow or white lettering against a

black, deep blue, or deep green background. Avoid pastels and red or green

lettering;

Too many words in a single visual will reduce contrast and legibility;

Generally, use no more than four colours in a single visual.

How many slides to use?

It is better to have more slides with less information on each slide, than fewer, more

detailed, slides. With a disciplined approach on your part, it will take exactly the

same amount of time to talk through one idea on each of six slides as it does to talk

through six ideas on one slide. Besides, making your audience look at the same slide

hil k h h h i i d k f i l i !

Edit Title to fit on 1 Line

Use maximum of 6-7 lines per slide

Edit long sentences to only one line

Use maximum of 6-8 words per line

- Use only one sub-level

- Boldface text carries more weight

Test slides for legibility and contrast

msc handbook sem 1

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