Multicentric Giant Cell Tumor of Bone and Paraganglioma

by Shintaro Iwata, Tsukasa Yonemoto, Takeshi Ishii, Akinobu Araki, Yoko Hagiwara, and Shin-ichiro Tatezaki

JBJS Case ConnectVolume 3(1):e23March 13, 2013

©2013 by The Journal of Bone and Joint Surgery, Inc.

Anteroposterior (Fig. 1-A) and lateral (Fig. 1-B) radiographs of the left knee joint and anteroposterior (Fig. 1-C) and lateral (Fig. 1-D) radiographs of the distal part of the tibia

demonstrating lytic bone lesions with trabeculation and cortical thinning ...

Shintaro Iwata et al. JBJS Case Connect 2013;3:e23

©2013 by The Journal of Bone and Joint Surgery, Inc.

Bone scintigraphy demonstrating increased radioisotope uptake in multiple areas, including the distal part of the left femur, the proximal part of the left tibia and fibula, and the distal part of the

left tibia.

Shintaro Iwata et al. JBJS Case Connect 2013;3:e23

©2013 by The Journal of Bone and Joint Surgery, Inc.

Anteroposterior radiographs of the left knee joint showing changes over time.

Shintaro Iwata et al. JBJS Case Connect 2013;3:e23

©2013 by The Journal of Bone and Joint Surgery, Inc.

Histopathological findings in the lesion of the distal part of the femur (Fig. 4-A), compatible with the diagnosis of bone GCT, and retroperitoneal tumor (Fig. 4-B), compatible with the diagnosis of

paraganglioma (hematoxylin and eosin stain, 200× magnifica...

Shintaro Iwata et al. JBJS Case Connect 2013;3:e23

©2013 by The Journal of Bone and Joint Surgery, Inc.

Axial CT scans showing a retroperitoneal tumor (Fig. 5-A, arrow) and a solitary pulmonary metastasis at the right lower lobe (Fig. 5-B, arrow).

Shintaro Iwata et al. JBJS Case Connect 2013;3:e23

©2013 by The Journal of Bone and Joint Surgery, Inc.