7/23/2019 Myopic Choroidal Neovascularisation

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Myopic choroidal neovascularisation: current

concepts and update on clinical management

 Br J Ophthalmol doi:10.1136/bjophthalmol-2014-305131

Received 7 March 2014; Revised 7 May 2014; Accepted 3 June 2014; Published Online First 1July 2014

Abstract

h!r!idal ne!vascularisati!n "#$% is a c!&&!n visi!n'threatenin( c!&plicati!n !) &y!pia

and path!l!(ical &y!pia* +espite si(ni)icant advances in understandin( the epide&i!l!(y, path!(enesis and natural hist!ry !) &y!pic #$, there is n! standard de)initi!n !) &y!pic #$

and its relati!nship t! a-ial len(th and !ther &y!pic de(enerative chan(es* .everal treat&ents

are available t! !phthal&!l!(ists, but /ith the advent !) ne/ therapies there is a need )!r )urtherc!nsensus and clinical &ana(e&ent rec!&&endati!ns* $ertep!r)in ph!t!dyna&ic therapy has

 been an established treat&ent )!r sub)!veal &y!pic #$ )!r &any years, but this treat&ent d!es

n!t rest!re visual acuity and is ass!ciated /ith l!n('ter& ch!ri!retinal atr!phy* M!re recently,

clinical trials investi(atin( the e))icacy and sa)ety !) anti'vascular end!thelial (r!/th )act!ra(ents in patients /ith &y!pic #$ have de&!nstrated substantial visual acuity (ains and

uality !) li)e increases c!&pared /ith ph!t!dyna&ic therapy* hese enhanced !utc!&es

 pr!vide updated evidence'based clinical &ana(e&ent (uidelines !) &y!pic #$, and increasethe need )!r a (enerally accepted de)initi!n )!r &y!pic #$* his revie/ critically su&&arises

the latest &y!pic #$ literature in the c!nte-t !) clinical e-perience and rec!&&ends a &y!pic

#$ treat&ent al(!rith&*