name of the drug : mirena component : intrauterine device ( levonorgestrel releasing iud) mechanism...
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Name of the drug : Mirena
Component : intrauterine device ( levonorgestrel releasing IUD)
Mechanism of action : endometrial shedding , cervical mucus thickening
Usage : 1-long-term contraception (up to 5 years) .2-dysmenorrhoea.3-menorrhagia.4-decrease incidence and severity of PID.
Dosage : release 20mcg/24 hours. Inserted in first 7 days of cycle.
Side effects : 1-headache,acne. 2-perforation (during insertion). 3-expulsion (first month). 4- 1% failure = ectopic.
Name of the drug :
Component : intrauterine device ( copper bearing IUD)
Mechanism of action : 1-inflammatory reaction (inhibit implantation). 2-toxic effect on sperm motility (inhibit fertilization).
Usage : long-term contraception (up to 5 years) .
Dosage : contain 380 mm copper. Inserted in first 7 days of cycle.
Side effects : 1-copper allergy. 2-dysmenorrhoea. 3-menorrhagia. 4-not protect against PID. 2-perforation (during insertion). 3-expulsion (first month). 4- 1% failure = ectopic.
Name of the drug : Yasmin.
Component : 30 mcg ethinylestradiol + 3mg drospirenone.
Mechanism of action : combined oral contraceptive pill (OCP).
Usage : contraception , severe menorrhagia.
Dosage : 1 tab/day for 21 days (5 – 25 of cycle) + 7 days tab free (3 weeks on, 1 week off)
Side effects :
Name of the drug : Primolut
Component : norethisterone 5mg
Mechanism of action : Progesterone.
Usage : contraception , severe menorrhagia , dysmenorrhoea , endometriosis.
Dosage : 1capsule /day for 3 months (250mg)
Side effects :1-Fluid retention.2-Breast discomfort.3-Dizziness.4-Depressed mood.
Name of the drug : Depo Provera
Component : Medroxyprogesterone acetate
Mechanism of action : Progesterone .
Usage : contraception , severe menorrhagia , dysmenorrhoea , endometriosis.
Dosage : 150 mg IM injection every 3 months.
Side effects :1-Fluid retention.2-Breast discomfort.3-Dizziness.4-Depressed mood.
Name of the drug :
Component : 11 white tablets (2mg estradiol) 10 brown tablets (2mg estradiol with 0.5mg norgestrel)
Mechanism of action : estrogen and progesterone.
Usage : HRT in menopause of premature ovarian failure.
Dosage : 1 tab/day for 21 days (5 – 25 of cycle) + 7 days tabfree (3 weeks on, 1 week off)
Side effects : Weight gain or lossHeadachelower abdominal pain
Name of the drug : Diane 35
Component : Cyproterone acetate (2 mg) + Ethinylestradiol (0.035 mg)
Mechanism of action : anti-androgen effect and estrogenic effect.
Usage : Hirsutism of PCOS , contraception.
Dosage : 1 tab/day for 21 days (5 – 25 of cycle) + 7 days tab free (3 weeks on, 1 week off)
Side effects :1-abdominal cramping, bloating.2-appetite changes.3-breast pain, tenderness, swelling.
Name of the drug :
Component : copy of the natural human FSH
Mechanism of action : stimulates the maturation of ova.
Usage : 1-ovulation induction 2-assisted reproductive techniques (IVF) 3- patient not respond to treatment with clomiphene citrate
Dosage :
Side effects : 1-ovarian cyst. 2-ovarian hyperstimulation syndrome (OHSS)
Name of the drug : Component : choriogonadotropin alfa : copy of the human hCG.
Mechanism of action : trigger ovulation (like LH hormone).
Usage : 1-ovulation induction 2-assisted reproductive techniques (IVF)
Dosage : 250 micrograms SC given 24 to 48 hours after the ovaries have produced follicles that are mature to ovulation.
Side effects : 1-ovarian cyst. 2-ovarian hyperstimulation syndrome (OHSS)
Name of the drug : Clomid
Component : clomiphene citrate.
Mechanism of action : estrogen receptor antagonist.
Usage : ovulation induction (Amenorrhoea , PCOS).
Dosage : 50mg/day for 5 days(day 2-6 of cycle) , try 100mg/day if ineffective.
Side effects : 1-hot flush.2-abdominal discomfort 3-ovarian hyperstimulation syndrome4-ectopic pregnancy…
Name of the drug : Diclair
Component : gonadotrophin.
Mechanism of action : human chorionic gonadotrophin.
Usage : ovulation induction.
Dosage : SC in 2-6 days of cycle (for 5 days).
Side effects :
Name of the drug : Fempro
Component : Letrozole.
Mechanism of action : aromatase inhibitor (inhibit estrogen formation)
Usage : premature ovarian failure.
Dosage : 2.5 mg tablet , used in 2-6 days of the cycle (for 5 days).
Side effects :
Name of the drug : DOSTINEX
Component : cabergoline
Mechanism of action : dopamine receptor agonist
Usage : hyperprolactinemia (infertility – galactorrhoea)
Dosage : 2 tabs/week for 4 weeks (0.5mg)
Side effects : 1-Nausea. 2-Sleepiness.
Name of the drug : Colette
Component : cabergoline.
Mechanism of action : dopamine receptor agonist.
Usage : hyperprolactinemia (infertility – galactorrhoea)
Dosage : 2tabs/week for 4 weeks (0.5mg)
Side effects :1-Nausea.2-Sleepiness.
Name of the drug : Dopergin
Component : Lisuride
Mechanism of action : partial dopamine receptor agonist..
Usage : hyperprolactinemia (infertility – galactorrhoea)
Dosage : 3 tab/day for 14 days (0.2mg) .
Side effects : 1-Nausea.2-Sleepiness.
Name of the drug : PIOPHAGE
Component : metformin.
Mechanism of action : decrese peripheral insulin resistance.
Usage : insulin resistance in PCOS.
Dosage :
Side effects :
Name of the drug : Regelle
Component : norethisterone.
Mechanism of action : progesterone.
Usage : regulate menstruation , endometriosis , dysmenorrhoea.
Dosage : 3 tabs /day for 10 days (5mg)
Side effects :1- breakthrough bleeding, spotting.2- changes in liver function.3- depression, headache, dizziness.4- fluid retention, bloating, weight gain.
Name of the drug : Zoladex.
Component : goserelin .
Mechanism of action : GnRH analogue (agonist).
Usage : menorrhagia , endometriosis.
Dosage : 3.6mg
Side effects :
Name of the drug : AMINOR.
Component : 5mg norethisterone acetate.
Mechanism of action : progesterone.
Usage : regulate menstruation , endometriosis , dysmenorrhoea.
Dosage : 1 tablet/day for 20 days.
Side effects :
Name of the drug : EXACYL
Component : tranexamic acid (cyklokapron).
Mechanism of action : anti-fibrinolytic , reversibly inhibit plasminogen activator.
Usage : menorrhagia.
Dosage : 1 tablet/day for 20 days.
Side effects : 1-nausea , vomitting.2-rarely thrombosis.
Name of the drug : MAGNESIUN SULFATE
Component : magnesium sulfate.
Mechanism of action : physiologic calcium antagonist.
Usage : prophylaxis and treatment of eclamptic fit.
Dosage : 4 g over 5–15 minutes followed by IV infusion , 1 g/hour for at least 24 hours.
Side effects :1- respiratory depression.2-drowsiness, confusion, loss of tendon reflexes3-oliguria.
Require Calcium Gluconate!
Name of the drug : Calcium Gluconate 10%
Component : calcium
Mechanism of action : antidote of magnesium sulfate toxicity.
Usage : used for magnesium sulfate overdose.
Dosage : 1g IV single dose slowly.
Side effects :1- tingling sensations.2-arrhythmia.
Name of the drug : Apresoline
Component : hydralazine hydrochloride
Mechanism of action : vasodilator.
Usage : pre-eclampsia.
Dosage : 5-10 mg slow IV injection, repeated after 20 minutes if necessary.
Side effects :1- palpitation.2-headache.3-flushing.4- dizziness,.
Name of the drug : Syntocinon
Component : oxytocin.
Mechanism of action : stimulate the smooth muscle contraction of the uterus.
Usage : 1-induction and augmintation of labor : 5IU in 500ml fluid.2-third stage of labor : 5IU when the anterior shoulder is delivered 3-post-partum hemorrhage : 10 IU bolus then 40IU infusion
maintain.
Dosage : discussed above.
Side effects :1- tachycardia.2- headache.3-nause,vomitting.
Name of the drug : Methrgine
Component : methylergonovine maleate.
Mechanism of action : increases the tone, rate of uterine contraction.
Usage : prevent PPH following delivery of the placenta, uterine atony.
Dosage : IV 0.2 mg, administered slowly.
Side effects :1- abdominal pain.2- hypertension.3-seizure.
Name of the drug :
Component : Enoxaparine : low molecular weight heparin (LMWH)
Mechanism of action : activate anti-thrombin III , heigher anti-factor Xa to antifactor IIa activity ratio.
Usage : prevention ,treatment of venous thromboembolic disease (DVT,PE)In prolong bedridden and surgical prophylaxis.
Dosage : 1mg/kg twice daily SC injection for 10 days (60 mg Sc q 2).
Side effects :1- bleeding (epistaxis , gum bleed).2- painful rash at the injection site.