name of the drug : mirena component : intrauterine device ( levonorgestrel releasing iud) mechanism...

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Page 1: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus
Page 2: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus
Page 3: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus
Page 4: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus
Page 5: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Mirena

Component : intrauterine device ( levonorgestrel releasing IUD)

Mechanism of action : endometrial shedding , cervical mucus thickening

Usage : 1-long-term contraception (up to 5 years) .2-dysmenorrhoea.3-menorrhagia.4-decrease incidence and severity of PID.

Dosage : release 20mcg/24 hours. Inserted in first 7 days of cycle.

Side effects : 1-headache,acne. 2-perforation (during insertion). 3-expulsion (first month). 4- 1% failure = ectopic.

Page 6: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug :

Component : intrauterine device ( copper bearing IUD)

Mechanism of action : 1-inflammatory reaction (inhibit implantation). 2-toxic effect on sperm motility (inhibit fertilization).

Usage : long-term contraception (up to 5 years) .

Dosage : contain 380 mm copper. Inserted in first 7 days of cycle.

Side effects : 1-copper allergy. 2-dysmenorrhoea. 3-menorrhagia. 4-not protect against PID. 2-perforation (during insertion). 3-expulsion (first month). 4- 1% failure = ectopic.

Page 7: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Yasmin.

Component : 30 mcg ethinylestradiol + 3mg drospirenone.

Mechanism of action : combined oral contraceptive pill (OCP).

Usage : contraception , severe menorrhagia.

Dosage : 1 tab/day for 21 days (5 – 25 of cycle) + 7 days tab free (3 weeks on, 1 week off)

Side effects :

Page 8: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Primolut

Component : norethisterone 5mg

Mechanism of action : Progesterone.

Usage : contraception , severe menorrhagia , dysmenorrhoea , endometriosis.

Dosage : 1capsule /day for 3 months (250mg)

Side effects :1-Fluid retention.2-Breast discomfort.3-Dizziness.4-Depressed mood.

Page 9: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Depo Provera

Component : Medroxyprogesterone acetate

Mechanism of action : Progesterone .

Usage : contraception , severe menorrhagia , dysmenorrhoea , endometriosis.

Dosage : 150 mg IM injection every 3 months.

Side effects :1-Fluid retention.2-Breast discomfort.3-Dizziness.4-Depressed mood.

Page 10: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug :

Component : 11 white tablets (2mg estradiol) 10 brown tablets (2mg estradiol with 0.5mg norgestrel)

Mechanism of action : estrogen and progesterone.

Usage : HRT in menopause of premature ovarian failure.

Dosage : 1 tab/day for 21 days (5 – 25 of cycle) + 7 days tabfree (3 weeks on, 1 week off)

Side effects : Weight gain or lossHeadachelower abdominal pain

Page 11: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Diane 35

Component : Cyproterone acetate (2 mg) + Ethinylestradiol (0.035 mg)

Mechanism of action : anti-androgen effect and estrogenic effect.

Usage : Hirsutism of PCOS , contraception.

Dosage : 1 tab/day for 21 days (5 – 25 of cycle) + 7 days tab free (3 weeks on, 1 week off)

Side effects :1-abdominal cramping, bloating.2-appetite changes.3-breast pain, tenderness, swelling.

Page 12: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus
Page 13: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug :

Component : copy of the natural human FSH

Mechanism of action : stimulates the maturation of ova.

Usage : 1-ovulation induction 2-assisted reproductive techniques (IVF) 3- patient not respond to treatment with clomiphene citrate

Dosage :

Side effects : 1-ovarian cyst. 2-ovarian hyperstimulation syndrome (OHSS)

Page 14: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Component : choriogonadotropin alfa : copy of the human hCG.

Mechanism of action : trigger ovulation (like LH hormone).

Usage : 1-ovulation induction 2-assisted reproductive techniques (IVF)

Dosage : 250 micrograms SC given 24 to 48 hours after the ovaries have produced follicles that are mature to ovulation.

Side effects : 1-ovarian cyst. 2-ovarian hyperstimulation syndrome (OHSS)

Page 15: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Clomid

Component : clomiphene citrate.

Mechanism of action : estrogen receptor antagonist.

Usage : ovulation induction (Amenorrhoea , PCOS).

Dosage : 50mg/day for 5 days(day 2-6 of cycle) , try 100mg/day if ineffective.

Side effects : 1-hot flush.2-abdominal discomfort 3-ovarian hyperstimulation syndrome4-ectopic pregnancy…

Page 16: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Diclair

Component : gonadotrophin.

Mechanism of action : human chorionic gonadotrophin.

Usage : ovulation induction.

Dosage : SC in 2-6 days of cycle (for 5 days).

Side effects :

Page 17: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Fempro

Component : Letrozole.

Mechanism of action : aromatase inhibitor (inhibit estrogen formation)

Usage : premature ovarian failure.

Dosage : 2.5 mg tablet , used in 2-6 days of the cycle (for 5 days).

Side effects :

Page 18: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : DOSTINEX

Component : cabergoline

Mechanism of action : dopamine receptor agonist

Usage : hyperprolactinemia (infertility – galactorrhoea)

Dosage : 2 tabs/week for 4 weeks (0.5mg)

Side effects : 1-Nausea. 2-Sleepiness.

Page 19: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Colette

Component : cabergoline.

Mechanism of action : dopamine receptor agonist.

Usage : hyperprolactinemia (infertility – galactorrhoea)

Dosage : 2tabs/week for 4 weeks (0.5mg)

Side effects :1-Nausea.2-Sleepiness.

Page 20: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Dopergin

Component : Lisuride

Mechanism of action : partial dopamine receptor agonist..

Usage : hyperprolactinemia (infertility – galactorrhoea)

Dosage : 3 tab/day for 14 days (0.2mg) .

Side effects : 1-Nausea.2-Sleepiness.

Page 21: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : PIOPHAGE

Component : metformin.

Mechanism of action : decrese peripheral insulin resistance.

Usage : insulin resistance in PCOS.

Dosage :

Side effects :

Page 22: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus
Page 23: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Regelle

Component : norethisterone.

Mechanism of action : progesterone.

Usage : regulate menstruation , endometriosis , dysmenorrhoea.

Dosage : 3 tabs /day for 10 days (5mg)

Side effects :1- breakthrough bleeding, spotting.2- changes in liver function.3- depression, headache, dizziness.4- fluid retention, bloating, weight gain.

Page 24: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Zoladex.

Component : goserelin .

Mechanism of action : GnRH analogue (agonist).

Usage : menorrhagia , endometriosis.

Dosage : 3.6mg

Side effects :

Page 25: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : AMINOR.

Component : 5mg norethisterone acetate.

Mechanism of action : progesterone.

Usage : regulate menstruation , endometriosis , dysmenorrhoea.

Dosage : 1 tablet/day for 20 days.

Side effects :

Page 26: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : EXACYL

Component : tranexamic acid (cyklokapron).

Mechanism of action : anti-fibrinolytic , reversibly inhibit plasminogen activator.

Usage : menorrhagia.

Dosage : 1 tablet/day for 20 days.

Side effects : 1-nausea , vomitting.2-rarely thrombosis.

Page 27: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus
Page 28: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : MAGNESIUN SULFATE

Component : magnesium sulfate.

Mechanism of action : physiologic calcium antagonist.

Usage : prophylaxis and treatment of eclamptic fit.

Dosage : 4 g over 5–15 minutes followed by IV infusion , 1 g/hour for at least 24 hours.

Side effects :1- respiratory depression.2-drowsiness, confusion, loss of tendon reflexes3-oliguria.

Require Calcium Gluconate!

Page 29: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Calcium Gluconate 10%

Component : calcium

Mechanism of action : antidote of magnesium sulfate toxicity.

Usage : used for magnesium sulfate overdose.

Dosage : 1g IV single dose slowly.

Side effects :1- tingling sensations.2-arrhythmia.

Page 30: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Apresoline

Component : hydralazine hydrochloride

Mechanism of action : vasodilator.

Usage : pre-eclampsia.

Dosage : 5-10 mg slow IV injection, repeated after 20 minutes if necessary.

Side effects :1- palpitation.2-headache.3-flushing.4- dizziness,.

Page 31: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus
Page 32: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Syntocinon

Component : oxytocin.

Mechanism of action : stimulate the smooth muscle contraction of the uterus.

Usage : 1-induction and augmintation of labor : 5IU in 500ml fluid.2-third stage of labor : 5IU when the anterior shoulder is delivered 3-post-partum hemorrhage : 10 IU bolus then 40IU infusion

maintain.

Dosage : discussed above.

Side effects :1- tachycardia.2- headache.3-nause,vomitting.

Page 33: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug : Methrgine

Component : methylergonovine maleate.

Mechanism of action : increases the tone, rate of uterine contraction.

Usage : prevent PPH following delivery of the placenta, uterine atony.

Dosage : IV 0.2 mg, administered slowly.

Side effects :1- abdominal pain.2- hypertension.3-seizure.

Page 34: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus

Name of the drug :

Component : Enoxaparine : low molecular weight heparin (LMWH)

Mechanism of action : activate anti-thrombin III , heigher anti-factor Xa to antifactor IIa activity ratio.

Usage : prevention ,treatment of venous thromboembolic disease (DVT,PE)In prolong bedridden and surgical prophylaxis.

Dosage : 1mg/kg twice daily SC injection for 10 days (60 mg Sc q 2).

Side effects :1- bleeding (epistaxis , gum bleed).2- painful rash at the injection site.

Page 35: Name of the drug : Mirena Component : intrauterine device ( levonorgestrel releasing IUD) Mechanism of action : endometrial shedding, cervical mucus