nanostructered multilayers of redox polymers and enzymes...
TRANSCRIPT
Nanostructered Multilayers of Redox Polymers and Enzymes for Molecular
Recognition and Electrical Signal Generation
Ernesto J. CalvoINQUIMAE. Departamento de Quimica Inorganica, Analitica y
Quimica Fisica. Facultad de Ciencias Exactas y NaturalesUniversidad de Buenos Aires, Argentina
BIBLIOGRAPHY
• A. Ulman. Introduction to Thin Films: From Langmuir–Blodgett to Self-Assembly, Academic Press, Boston (1991).
• G. Decher. Science 277, 1232 (1997).
• Decher, G.; Schlenoff, J. B. Multilayer Thin Films: Sequential Assembly of Nanocomposite Materials;Wiley-VCH: Weinheim, 2003.
A.J. Bard, Integrated Chemical Systems, John Wiley & Sons, 1994
INTEGRATED CHEMICAL SYSTEMS
Nanostructured Multilayer Films
Langmuir-Blodgett Films
Langmuir-Blodgett Trough
A stearic acid isotherm
Forces
Electrostatic ≈ 1/r2
Van der Waals ≈1/r6
πA = kT
Molecular Film Transfer to a Surface
Langmuir-Blodgett Films
Hydrophobic SurfaceFormation of a second layer
Hydrophillic surface
Types of LB films
Isotherm of Fatty acid in the water-air interphase
75 100 125 150 175 200
0
10
20
30
40
50
60Pr
essu
re (m
N/m
)
Trough area (cm2)
Fatty acid on water subphase Fatty acid on CdCl2 subphase
16 18 20 22 24 26 28 30 32 34 36-5
0
5
10
15
20
25
30
35
40
Pres
sure
, mN
/m
Molecular area, A2
C18NH2 on water
5 10 15 20 25 30 35 40
0
10
20
30
40
50
Pres
sure
Molecular area
amine pH=9 pH=3 pure water
Effect of Molecular Structure
60 80 100 120 140 160 180-5
0
5
10
15
20
25
30
35
40Pr
essu
re
Molecular area
DODA on water
Transfer of Molecular Layer to a Solid Hydrophobic Surface
0 500 1000 1500 2000 250040
60
80
100
120
140A
rea,
cm
2
Time, Sec
AreaA,cm²
Gil Markovich, C. Patrick Collier,Sven E. Henrichs, Francoise Remacle, Raphael D. Levine, andJames R. Heath*Acc. Chem. Res., 32 (5), 415 -423, 1999
Nanoparticles LB Film