NANS I3Technology Gaps in Intrathecal

Drug Delivery Systems

Stanley Fisher, M.D.Associate Professor of NeurologyWeill Cornell Medical CollegeCo-Director , Movement Disorders and Neurorehabilitation CenterMethodist Neurological InstituteHouston, Texas

Desired improvements in IT Drug Delivery?

• Reliable pumping mechanism.• Long battery life.• Troubleshooting tools.• Enhanced safety features. • Simple programming.• Dependable catheter.

MedStream™ Programmable Pump• The system consists of:

– Implantable Pump • 20mL and 40mL reservoirs

– Intrathecal Catheter(s)• SureStream™ Intraspinal• Codman® Silicone Intraspinal

– Control Unit

• Indicated for: – Intrathecal delivery of baclofen for

severe spasticity.

Benefits• Simple & durable design.

– Only one moving part.– > 6 million cycles without failure;

equivalent to 78 years of service.• Accurate dosage within 10%

across the entire flow range.

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Benefits• Fewer revision surgeries.• Higher infusion rates can be

used without effecting battery life.– Typical peristaltic pump lasts only

5-7 years depending on flow rate.

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Benefits• Easily verify drug remaining in

pump without emptying it.• Confirm that drug has entered

reservoir and not pump pocket.

• Useful diagnostic tool when troubleshooting system.

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Benefits• Patients can safely undergo

MRI procedures.• No binding of gears / rotors.• No need to stop flow or

empty pump before MRI.– Confirm pump status after MRI

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Benefits• Raised refill port makes

locating easy.• Positive pressure provides

tactile assurance that you are in the port.

• Drug Volume Gauge verifies that refill of pump has occurred.

Safe Pump RefillsPrevent pump pocket refill errors.

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Easy and Fast.

Benefits• Simple and flexible dosing

options. • Icon-driven user interface.• Backlit full-color screen.• Simple roller wheel control.

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Benefits• Improves refill procedure

efficiency and patient comfort.

• Rechargeable CU battery– Never uses the pump battery for

communication extending pump battery life.

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Look Inside

Kinking No KinkingSilicone SURESTREAM

Kink ResistantThe titanium coil design

ensures flow of medication without occlusion.

SureStream™ kink resistant catheter.

Future Technology Needed

• Dual chamber pump.• Catheter flow sensor.• Therapy data trending.• More drug options.

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Thank You