national list of essential medicines - who
TRANSCRIPT
Republic of Sudan
National List ofEssential Medicines
Federal Ministry of Health
Fifth List2007
General Directorate of Pharmacy
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Introduction
Anaesthetics
Analgesics , antipyretics, non-steroidal anti-inflammatory medicinesand medicines used to treat gout and disease modifying agents in rheu-matoid disorders
Antiallergics and medicines used in anaphylaxis
Antidotes and other substances used in poisonings
Anticonvulsant/ Antiepileptics
Anti-infective medicines
Antimigraine medicines
Antineoplastic, immunosuppressive medicines and medicines used inpalliative care
Antiparkinsonism medicines
Medicines affecting the blood
Blood products and blood substituents
Cardiovascular medicines
Dermatological medicines (topical)
Diagnostic agents
Disinfectants and antiseptics
Diuretics
Gastrointestinal medicines
Hormones, other endocrine medicines and contraceptives
Immunologicals
Muscle relaxants and cholinesterase inhibitors
Ophthalmological preparation
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Contents
Oxytocics and antioxytocics
Peritoneal dialysis solutions
Pyschotherapeutic medicines
Medicines acting on the respiratory tract
Solutions correcting water electrolyte and acid-base disturbances
Vitamins and minerals
Medicines used in ear/nose/throat and oropharynx
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Development of National List of Essential Medicines
In 1981 the Ministry of Health formulated a national drug policy (NDP) based on theconcept of essential medicines. The first component of the NDP to be implemented wasthe selection of a national list of essential drugs (NLED). Although the first NLED wasselected in 1981 and first published in 1982 yet it was not officially adopted.
In 1985 a national workshop was convened in Khartoum in which the 1982 NLEDwas revised and updated and levels of use allocated, but again it was not officially adopted.
In 1987 the NLED was revised by the Standing Committee for Drug Products Reg-istration. The revised NLED was adopted by Ministerial Order No. 7 dated 15 October1987 , printed in English and widely distributed-
In November 1993 a national workshop was convened in Khartoum and revised1987 NLED. The updated NLED was eventually adopted by Ministerial Order No. 4 dat-ed 15 April 1995 printed in English (original) and Arabic and widely distributed .
In November 2001 a national workshop was convened in Khartoum and revised1995 NLED. The updated list although not officially adopted, yet it was widely acceptedand used. Eventually the NLED was updated by the Standing Committee for Drug Prod-ucts Registration in May 2004 and its title was changed to the National List of EssentialMedicines, using the word "medicine" instead of "drug" as adopted by the World HealthOrganization (WHO). It is planned to be adopted by the Federal Ministry of Health,printed and widely distributed during the current year 2006.
Levels of use
AA. Medicines used in primary heath care units, dressing stations and all other health in-stitutions.
A. Medicines used in dispensaries and health centers run by medical assistants (in addi-tion to AA medicines).
B. Medicines used in rural hospitals and health centers run by medical officers (in addi-tion to A, AA medicines).
C. Medicines used in hospitals with specialist departments (in addition to A, AA, B medicines).
S. Medicines used in specialized centers or specialized units in some designated hospi-tals (in addition to all other essential medicines).
Medicines marked in italics (* IMCI, …A) are B or C level medicines which are pre-scribed and used by health workers trained in Integrated Management of Childhood Ill-ness (IMCI) in specific cases only in dispensaries and rural health centers.
Introduction
Explanatory notes
* Following the system adopted in WHO Model List of Essential Medicines when thestrength of a medicine is specified in term of a selected salt or ester this is mentioned inbrackets. When it refers to the active moiety the name of the salt or ester in brackets ispreceded by the word “as “.
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Medicine Route of administration, dosageforms and strengths
Level ofUse
Ether, anaesthetic
Etomidate
Halothane
Isoflurane
Ketamine
Nitrous oxide
Oxygen
Propofol
Thiopental
1.2 Local anaesthetics
Bupivacaine
Ephedrine(adrenaline)
Lidocaine
inhalation
injection ,2 mg/ml in 10-ml ampoule
inhalation
inhalation , bottle 100-ml or 200-ml
injection ,50 mg(as hydrochloride)/ml in10-ml vial
inhalation
inhalation ( medicinal gas)
injection, 1 % (emulsion) 10 mg/ml in 20-ml ampoule10 mg/ml in 50-ml vial 10mg/ml in 50-ml pre-filled syringe (for use withDiprifusor )
powder for injection , 0.5 g(sodium salt) in 20-ml vial
injection,0.25%, 0.5% (hydrochloride) in vial injection for spinal anesthesia, 0.5%(hydrochloride) in 4-ml ampoule to be mixed with7.5% glucose solution
injection, 30mg (hydrochloride) /ml in 1-ml am-poule (for use in spinal anaethesia during deliveryto prevent hypotension)
injection, 1%, 2% (hydrochloride) in vialinjection, 1%, 2% + epinephrine (adrenaline)1:200 000 in vial
C
C
C
C
B
B
B
CCCC
C
CC
C
AB
1. Anaesthetics
1.1 General anaesthetics and oxygen
1
Medicine Route of administration, dosageforms and strengths
Level ofUse
Ropivicaine
1.3 Preoperative medication
Atropine
Diazepam
Droperidol
Fentanyl
Glycopyrronium
Hyoscinehydrobromide
Metoclopramide
Midazolam
Morphine
Pethidine
Promethazine
Ondansterone
Remifentanil
B
CB
C
B
BBC
CC
C
C
B
B
C
B
B
B
BB
C
injection for spinal anaesthesia, 5%(hydrochloride) in 2-ml ampoule to be mixed with7.5% glucose solutiontopical forms , 2-10% (hydrochloride)dental cartridge, 2% ( hydrochloride)+ epinephrine 1:80 000
injection, 7.5 mg/ml in 10-ml ampoule
injection,1mg ( sulfate ) in 1-ml ampoule
injection, 5mg/ml in 2-ml ampouletablet, 5 mgrectal solution, 2mg/ml in 1.25 ml, 2.5 ml rectal tube
injection, 5mg/ml in 2-ml ampouleinjection, 30mg (hydrochloride)/ml in ampoule
injection, 50microgram /ml ( as citrate ) in 2-ml ampoule
injection, 200 microgram ( bromide) in 1-ml ampoule
injection, 400 microgram in 1-ml ampoule
injection, 5 mg/ml in 2-ml ampoule
injection, 5mg (as hydrochloride)/ml , in 2-ml; 5-mlampoule
injection,10mg(sulfate or hydrochloride) in 1-ml ampoule
injection,50mg(as hydrochloride) in 1-ml ampoule
elixir or syrup,5 mg ( hydrochloride)/5ml
injection, 2 mg(as hydrochloride)/ ml in 2-ml ampouletablet, 4 mg (as hydrochloride)
powder for injection, 5mg (as hydrochloride) in vial
2
Medicine Route of administration, dosageforms and strengths
Level ofUse
1.4 Antagonists for central and respiratory depression due tobenzodiazepines
Flumazenil
2. Analgesics , antipyretics, non-steroidal anti-inflammatorymedicines and medicines used to treat gout
2.1 Non-opioids
Acetylsalicylic acid
Ibuprofen
Indomethacin
Paracetamol
Naproxen
Piroxicam
Probenecid
Sulfinpyrazone
Tenoxicam
2.2 Opioid Analgesics
Codeine
Morphine
injection, 100 microgram/ml in 5-ml ampoule
tablet , 300 mg,100 mgsuppository, 50 – 150 mg
tablet , 200 mg,400 mg,600mg
capsule or tablet , 25 mg
tablet , 500 mgsyrup , 125 mg/5 mlsuppository, 100 mg
tablet, 250mg , 500 mg
tablet, 10mg , 20 mg
tablet, 500 mg
tablet, 100mg, 200 mg
tablet, 10mg, 20 mg
tablet , 30 mg ( phosphate)
injection,10mg (sulfate or hydrochloride) in 1-mlampouletablet, 10 mg ( sulfate )oral solution, 10mg (hydrochloride or sulfate) /5ml
C
AAA
B
C
AAAA
B
C
C
C
C
C
C
B
BB
3
Medicine Route of administration, dosageforms and strengths
Level ofUse
Pethidine
2.3 Medicines used to treat gout
Allopurinol
Colchicine
2.4 Disease modifying agents used in rheumatic disorders
Azathioprine
Chloroquine
Cyclophosphamide
Gold
Methotrexate
Penicillamine
Sulfasalazine
3.Antiallergics and drugs used in anaphylaxis
Epinephrine (adrenaline)
Chlorphenamine
Dexamethasone
Hydrocortisone
Prednisolone
BC
C
C
C
C
C
C
C
C
C
BA
BBB
BB
B
B
injection, 50 mg (hydrochloride ) In 1-ml ampouletablet, 50mg, 100 mg
tablet , 100 mg
tablet, 500 microgram
tablet, 50 mg
tablet, 100 mg, 150 mg(as phosphate or sulfate)
tablet, 25 mg
injection, 50 mg/ml in 0.5 ml ampoule
tablet, 10 mg (as sodium salt)
capsule or tablet, 250 mg
tablet, 500 mg
injection, 1 mg ( as hydrochloride)in 1-ml ampoule* IMCI, pre referral treatment
tablet, 4 mg ( hydrogen maleate)syrup, 2 mg/5mlinjection, 10 mg(as hydrogen maleate) in 1-ml ampoule
tablet, 500 microgram , 4 mginjection, 4 mg (as sodium phosphate) in 1-ml ampoule
powder for injection, 100 mg ( as sodium succinate )in vial
tablet, 5 mg , 25mg
4
Medicine Route of administration, dosageforms and strengths
Level ofUse
4. Antidotes and other substances used in poisonings4.1 Non-specific
Charcoal - activated
Ipecacuanha
4.2 Specific
Acetylcystine
Atropine
Calcium gluconate
Deferoxamine
Digoxin specific antibodies fragments
Dimercaprol
Methionine
Methylthioniniumchloride (methylene blue)
Naloxone
Penicillamine
Potassium ferric hexacyanoferrate (II).2H2O (Prussian blue)
Sodium calcium edetate
Sodium nitrite
Sodium thiosulfate
.
.
powder
syrup, containing 0.14% ipecacuanhaalkaloids calculated as emetine
injection, 200 mg/ml in 10- ml ampoule
injection,1 mg(sulfate) in 1-ml ampoule
injection, 100 mg/ml in 10- ml ampoule
powder for injection, 500 mg ( mesiliate) in vial
powder for infusion, 38 mg in vial
injection in oil , 50 mg/ml in 2-ml ampoule
tablet, 250 mg (racemate)
injection, 10 mg/ml in 10-ml ampoule
injection, 400 microgram ( hydrochloride ) in 1-ml ampoule
capsule or tablet, 250 mg
powder for oral administration
injection, 200 mg/ml in 5-ml ampoule
injection, 30 mg/ml in 10- ml ampoule
injection, 250 mg/ml in 50-ml ampoule
A
B
B
B
B
B
S
S
B
S
B
B
C
S
S
S
5
Medicine Route of administration, dosageforms and strengths
Level ofUse
5. Anticonvulsants/ antiepileptics
Carbamazepine
Clonazepam
Diazepam
Ethosuximide
Lamotrigine
Phenobarbital
Phenytoin
Topiramate
Valproic acid
Vigabatrine
6. Anti-infective medicines
6.1 Anthelmintic medicines
6.1.1 Intestinal anthelminthics
Albendazole
Levamisole
BB
B
BCA
SS
C
BBB
B
BC
C
C
C
AA
B
scored tablet, 100 mg,200 mg, 400 mg,syrup, 100 mg/5ml
scored tablet, 500 microgram
injection, 5 mg/ml in 2-ml ampoule rectal solution, 2mg/ml in 1.25 ml, 2.5 ml rectal tube*IMCI convulsing child
capsule, 250 mgsyrup, 250 mg/5ml
tablet, 25 mg, 50 mg, 100 mg and 200 mg
tablet , 15 mg , 30 mg, 100mginjection, 200 mg/ml in 1-ml ampouleelixir, 15 mg/5 ml
capsule or tablet, 25mg, 50 mg,100mg ( sodium salt )oral suspension, 30 mg/ 5 ml (sodium salt)injection, 50 mg ( sodium salt)/ml in 5-ml vial
tablet, 25 mg, 100 mg, 200 mg
enteric coated tablet ,200 mg,500mg ( sodium salt)
scored tablet, 500 mg
chewable tablet, 400 mg
tablet, 50 mg, 150 mg ( as hydrochloride)
6
Medicine Route of administration, dosageforms and strengths
Level ofUse
Mebendazole
Niclosamide
Praziquantel
Pyrantel
6.1.2. Antifilarials
Diethylcarbamazine
Ivermectin
6.1.3. Antischistosomals and antitrematode medicines
Praziquantel
Triclabendazole
6.2 Antibacterials
6.2.1 Beta –lactam medicines
Amoxicillin
Amoxicillin + clavulanic acid
Ampicillin
Benzathinebenzylpenicillin
A
B
B
BB
C
C
B
B
AA
C
B
B
A
chewable tablet, 100 mg, 500 mg
chewable tablet, 500 mg
tablet, 150mg, 600mg
chewable tablet, 250 mg ( as embonate )oral suspension, 50 mg/ml (as embonate)
tablet, 50 mg,100mg ( dihydrogen citrate)
scored tablet, 3 mg, 6 mg
tablet, 600 mg
tablet, 250 mg
capsule or tablet, 250 mg,500mg (anhydrous )powder for oral suspension 125mg (anhydrous)/5ml
tablet, 500 mg + 125 mg
powder for injection, 500 mg,1gm ( as sodium salt)in vial
powder for injection, 2.4 million IU, 1.2 million IU,600 000 IU in 5-ml vial
*600 000 IU in 5-ml vial-IMCI prereferraltreatment
7
Medicine Route of administration, dosageforms and strengths
Level ofUse
Benzylpenicillin
Cefaclor
Cefadroxil
Cefixime
Cefpirome
Ceftazidime
Ceftriaxone
Cloxacillin
Imipenem + cilastin
Phenoxymethyl penicillin
Procaine penicillin
6.2.2 Other antibacterials
Azithromycin
Chloramphenicol
A
CC
CC
CC
C
C
C
CC
C
C
C
BA
BB
BBB
powder for injection, 600 mg ( = 1 million IU) or3g ( = 5 million IU) ( as sodium or potassiumsalt ) in vial
capsule, 500 mg (monohydrate)syrup, 125 mg/5ml
capsule, 250 mg , 500 mg (monohydrate)syrup, 125 mg/5ml
capsule, 400 mgpowder for oral suspension, 100 mg/5ml
powder for injection, 1 g in vial
powder for injection , 250 mg (as pentahydrate) in vial
powder for injection, 250 mg(as sodium salt ) in vial
capsule, 500 mg ( as sodium salt),powder for injection, 500 mg and 1g( as sodiumsalt ) in vial ;powder for oral suspension, 125 mg/5ml
powder for injection, 250 mg (as monohydrate) +250 mg, 500mg+500mg (as sodium salt) in vial
tablet, 250 mg (as potassium salt)
powder for injection, 1g( = 1 million IU) in vial* IMCI, when referral is not possible
capsule,250mg,500mgsuspension, 200mg/5ml
capsule, 250 mgoral suspension, 150mg (as palmitate salt)/5mloily suspension for injection, 0.5 g(as sodiumsuccinate)/ml in 2-ml ampoule
8
Medicine Route of administration, dosageforms and strengths
Level ofUse
Ciprofloxacin
Clarithromycin
Clindamycin
Doxycycline
Erythromycin
Gentamicin
Metronidazole
Nalidixic acid
Nitrofurantoin
Spectinomycin
Sulfamethoxazole +
Trimethoprim
B
A
C
B
C
B
A
B
C
B
A
A
B
A
C
C
C
A
C
C
AA
AA
B
powder for injection, 1 g (sodium succinate) in vial
* IMCI, pre referral treatment
tablet, 250 mg ( as hydrochloride )
powder for injection, 500 mg (lactobionate) in vial
capsule, 150 mg, injection, 150 mg (as phosphate)
/ml in 2-ml ampoule
capsule or tablet, 100 mg (as hydrochloride)
* IMCI, first line for cholera
capsule or tablet, 250 mg ( as stearate or ethyl
succinate )
powder for injection, 500 mg ( as lactobionate) in vial
injection, 10 mg , 40 mg ( as sulfate )/ml in 2-ml vial
* IMCI, when referral is not possible
tablet, 250 mg
tablet, 500 mg
oral suspension, 200 mg ( as benzoate )/5ml
injection , 500 mg in 100-ml vial
vaginal tablet, 500 mg, 1 g
tablet, , 250 mg ,500 mg
* IMCI, second line for Dysentery
tablet, 100 mg
powder for injection, 2 g (as hydrochloride) in vial
tablet, (100 mg + 20 mg ), (400 mg + 80 mg)
oral suspension, 200 mg + 40 mg/5ml
injection, (80 + 16 mg)/ml , in10-ml ampoule
9
Medicine Route of administration, dosageforms and strengths
Level ofUse
Tobramycin
Trimethoprim
Vancomycin
6.2.3 Antileprosy medicines
Aciclovir
Clofazimine
Dapsone
Rifampicin
6.2.4 Antituberculosis medicines
Ethambutol
Isoniazid
Isoniazid+Ethambutol
Pyrazinamide
Rifampicin
Rifampicin+Isoniazid
Streptomycin
6.3 Antifungal medicines
Amphotericin B
Fluconazole
C
CC
C
CC
B
B
B
B
B
B
B
B
B
B
C
BBB
injection, 10 mg, 40 mg (as sulfate) in 2-ml vial
tablet, 100 mg, 200 mginjection, 20 mg/ml in 5-ml ampoule
powder for injection, 250 mg (as hydrochloride) in vial
tablet, 200 mgpowder for injection, 250 mg (as sodium salt) in vial
capsule, 50 mg ,100 mg
tablet, 25 mg, 50 mg,100 mg,
capsule or tablet, 150 mg, 300 mg
tablet, 100mg,400 mg ( hydrochloride )
tablet, 100 mg, 300mg
tablet, 150 mg + 400 mg
tablet, 400 mg
tablet, 150mg,300mg
tablet, 150mg + 75 mg
powder for injection,750 mg, 1 g ( as sulfate ) in vial
powder for injection, 50 mg in vial
capsule, 50 mg
injection, 2 mg/ml in vial
oral suspension, 50 mg/5 ml
10
Medicine Route of administration, dosageforms and strengths
Level ofUse
Flucytocine
Griseofulvin
Ketoconazole
Nystatin
Potassium iodide
6.4 Antiviral medicines
6.4.1 Antiherpes medicines
Aciclovir
6.4.2 Antiretroviral medicines
6.4.2.1 Nucleoside reverse transcriptase inhibitors
Abacavir (ABC)
Didanosine (ddi)
Lamivudine (3TC)
Stavudine (d4T)
Zalcitabin (ddc)
Zidovudine (ZDV or AZT)
CC
B
C
BBB
B
CC
CC
C
CC
CC
C
CCCC
capsule, 250 mginfusion, 2.5 g in 250-ml
capsule or tablet , 125 mg, 250 mg
tablet, 200 mg
tablet, 100 000 IU , 500 000 IUpessary, 100 000 IUlozenges, 100 000 IU
saturated solution
tablet,200mgpowder for injection, 250mg (as sodium salt) in vial
tablet, 300 mg (as sulfate)oral solution, 100 mg (as sulfate)/5ml
buffered chewable tablet, 25 mg, 100 mg
tablet, 150 mgoral solution, 50 mg/5ml
capsule, 15 mg, 20 mg, 30 mg, 40 mgpowder for oral solution, 5 mg/5ml
tablet, 0.75 mg
tablet, 300 mgcapsule, 100 mg, 250 mgoral solution or syrup, 50 mg/5mlsolution for IV infusion, 10 mg/ml in 20-ml vial
11
Medicine Route of administration, dosageforms and strengths
Level ofUse
Zidovudine+lamivudine+ abacavir
6.4.2.2 Non-nucleoside reverse transcriptase inhibitors
Delvairidine (DLV)
Efavirenz (EFV or EFZ)
Nevirapine (NVP)
6.4.2.3 Protease inhibitors
Indinavir (IDV)
Iopinavir + ritonavir(LPV/r)
Nelfinavir (NFV)
Ritonavir (RTV)
Saquinavir (SQV)
6.5 Antiprotozoal medicines
6.5.1 Antiameobic and antigardiasis medicines
Diloxanide
Metronidazole
C
C
CC
CC
C
C
C
CC
CC
C
A
ABAB
tablet, 300 mg+ 150 mg+ 300 mg
capsule, 100 mg
tablet, 200 mgoral suspension, 50 mg/5ml
tablet, 200 mgoral solution, 150 mg/5ml
capsule, 200 mg, 333 mg (as sulfate)
capsule, 133.3 mg+ 33.3 mg
oral solution, 400 mg+ 100 mg/5ml
tablet, 250 mg (as mesilate)oral powder, 50 mg/5ml
capsule, 100 mgoral solution, 400 mg/5ml
capsule, 200 mg
tablet, 500 mg ( furoate )
tablet, 250 mgtablet, 500 mgoral suspension, 200 mg ( as benzoate )/5 mlinjection, 500 mg in 100-ml vial
12
Medicine Route of administration, dosageforms and strengths
Level ofUse
6.5.2 Antileishmaniasis medicines
Amphotericin B
Pentamidine
Sodium stibogluconate
6.5.3 Antimalarial medicines
6.5.3.1 For curative treatment
(a) For treatment of uncomplicated malaria
Artemether +lumefantrine
Artesunate(AS) /sulphadoxine +pyrimethamine(SP)
Quinine
(b) For treatment of severe malaria
Artemether
Artesunate
Artesunate (AS)/sulphadoxine+pyrimethamine (SP)
Quinine
C
C
C
A
AA
B
BA
B
B
AA
B
B
powder for injection, 50 mg in vial
powder for injection, 200 mg, 300mg (isetionate) in vial
injection, 33%, equivalent to approx. 10% antimony, in 30-ml vial
tablet, 20 mg + 120 mg
tablets, ( 50 mg/ 500 mg + 25 mg ),(100 mg/ 500mg + 25 mg ),
tablet, 300 mg ( as bisulfate or dihydrochloride orsulfate)injection, 300 mg (as dihydrochloride) /ml in 2-ml ampoule* IMCI, pre referral treatment
injection, 40 mg/ml , 80 mg/ml
suppository, 50 mg , 200 mg
tablets, ( 50 mg/ 500 mg + 25 mg ),(100 mg/ 500mg + 25 mg ),
injection, 300 mg (as dihydrochloride)/ml in 2-mlampoule tablet, 300 mg ( as bisulfate or sulfate)
13
Medicine Route of administration, dosageforms and strengths
Level ofUse
(c) for prophylaxis
Atovaquone + proguanil
Mefloquine
6.5.4. Antipneumocystosis and antitoxoplamosis medicines
Pentamidine
Pyrimethamine
Sulphamethoxazole+ trimethoprim
6.5.5 Antitrypanosomal medicines
6.5.5.1 African trypanosomiasis
Eflomithine
Melarsoprol
Pentamidine
Suramin sodium
6.5.5.2 American trypanosomiasis
Benznidazole
Nifurtimox
Insect repellants
Diethyltoluamide
7. Antimigraine medicines
B
B
C
C
C
C
C
CC
C
C
C
C
tablet, 250 mg + 100 mg
tablet, 250 mg (as hydrochloride)
tablet, 200mg, 300 mg
tablet, 25 mg
injection, 80 mg + 16 mg/ml in 5-ml and 10-ml am-poule
injection, 200mg (hydrochloride )/ml in 100-ml bottle
injection , 3.6% solution
powder for injection, 200 mg (isetionate) in vialpowder for injection, 300 mg (isetionate or mes-ilate ) in vial
powder for injection, 1 g in vial
tablet, 100 mg
tablet, 30 mg, 120 mg , 250 mg
topical solution, 50%, 75%
14
Medicine Route of administration, dosageforms and strengths
Level ofUse
7.1 For treatment of acute attack
Acetylsalicylic acid
Cyclizine
Ergotamine
Paracetamol
Sumatriptan
Zolmitriptan
7.2 For prophylaxis
Pizotifen
Propanolol
8. Antineoplastic and Immunosuppressive medicines andmedicines used in palliative care
8.1 Immunosuppressive medicines
Azathioprine
Ciclosporin
8.2. Cytotoxic medicines
Asparaginase
Bleomycin
Busulfan
Capecitabine
Carboplatin
AA
B
C
AA
C
C
C
B
CC
CC
S
S
S
S
S
tablet, 300 mg
tablet, 50 mg ( hydrochloride )
tablet, 1 mg ( tartrate )
tablet, 500 mg
tablet, 100 mg ( as succinate )
tablet, 2 mg, 5 mg
tablet, 500mg (as hydrogen maleate)
tablet, 10mg, 20mg, 40 mg ( hydrochloride )
tablet, 50 mg powder for injection, 100 mg (as sodium salt) in vial
capsule, 25 mg concentrate for injection, 50 mg/ml in 1-ml ampoule
powder for injection, 10 000 IU / vial
powder for injection , 15 mg (as sulfate) in vial
tablet, 2 mg
tablet, 150mg, 500 mg
injection, 10mg/ml in 5-ml vial
15
Medicine Route of administration, dosageforms and strengths
Level ofUse
Carmustine
CCNU
Chlorambucil
Chlormethine
Cisplatin
Cyclophosphamide
Cytarabine
Dacarbazine
Dactinomycin
Daunorubicin
Docetaxel
Doxorubicin
Epirubicine
Etoposide
Flurouracil
Hydroxyurea
Idarubicine
Ifosfamide
Levamisole
S
S
C
C
C
CC
S
S
S
S
S
S
S
SS
S
S
S
S
S
powder for injection, 100 mg
capsule, 40 mg
tablet, 2 mg, 5 mg
powder for injection, 10 mg (hydrochloride) in vial
powder for injection, 10 mg, 50mg in vial
tablet, 25mgpowder for injection, 200mg , 500mg, 1 gm in vial
powder for injection, 100 mg in vial
powder for injection ,200 mg in vial
powder for injection, 500 microgram in vial
powder for injection, 20 mg, 50mg, (as hydrochloride) in vial
injection,concentrate for intravenous infusion40mg/ml in 2-ml vial
powder for injection , 10 mg, 50 mg (hydrochloride) in vial
powder for injection, 10 mg, 50 mg in vial
capsule, 100 mginjection, 20mg/ml in 5-ml ampoule
injection, 50 mg/ml in 5-ml ampoule
capsule, 500 mg
injection, 5 mg, 10 mg
powder for injection, 1 g in vial
tablet, 50 mg (as hydrochloride)
16
Medicine Route of administration, dosageforms and strengths
Level ofUse
Melphalan
Mercaptopurine
Methotrexate
Paclitaxel
Procarbazine
Thioguanine
Thiotepa
Vinblastine
Vincristine
Vindesine
8.3 Hormones and antihormones
Arimidex
Dexamethasone
Flutamide
Fosfosterol
Goserelin
Hydrocortisone
Medroxy-progesterone
S
S
SS
S
S
S
S
S
S
S
C
C
C
CC
CC
C
C
tablet, 2 mg, 5 mg
tablet, 50 mg
tablet, 2.5mg ( as sodium salt)powder for injection, 50 mg ( as sodium salt) in vial
injection, concentrate for intravenous infusion6mg/ml, 5-ml;16.7-ml vial
capsule, 50 mg ( as hydrochloride)
tablet , 40 mg
powder for injection, 15 mg in vial
powder for injection, 10 mg (sulfate) in vial
powder for injection, 1 mg ,5mg (sulfate) in vial
powder for injection, 5 mg (sulfate) in vial
tablet, 1 mg
injection, 4mg (phosphate or disodium salt) in 1-mlampoule
tablet, 250 mg
tablet, 120 mginjection, 60 mg/ml in 5-ml ampoule
tablet, 1 mg (as acetate)implant injection, 3.6 mg (as acetate) in syringe
powder for injection,100 mg (as sodium succinate) in vial
injection, 500 mg (depot)
17
Medicine Route of administration, dosageforms and strengths
Level ofUse
Megesterole
Prednisolone
Tamoxifen
8.4 Other antitumor medicines, medicines used with antitumormedicines and medicines used in palliative care
8.4.1 Other antitumor medicines
Alpha interferon
Imatinib mesylate
8.4.2 Medicines used with antitumor medicines
Calcium folinate
Filgastrim
Mesna
8.4.3 Medicines used in palliative care
Bonefosph
Codeine
Fentanyl
Calcium folinate
Mitomycin
Mitoxantrone
C
BB
C
S
S
SSS
S
S
C
C
C
CC
C
C
tablet, 40 mg, 160 mg (acetate)
tablet, 5 mg, 25 mgpowder for injection, 25 mg (as sodium phosphateor sodium succinate) in vial
tablet, 10mg, 20 mg (as citrate)
injection, 5 million IU/ml in 1-ml vial
capsule, 100 mg
tablet, 15 mg, 50 mginjection, 3 mg/ml in 10-ml ampouleinjection, 15 mg
injection, 30 million units (300 micrograms)/ml in 1-ml vial
injection, 100 mg/ml in 4-ml ampoule
tablet, 400 mg
tablet, 15 mg, 30 mg (phosphate)
adhesive patches
tablet, 15 mginjection, 3mg/ml in 10-ml ampoule
injection, 10 mg in vial
injection, 2 mg/ml (as hydrochloride) in 10-ml vial
18
Medicine Route of administration, dosageforms and strengths
Level ofUse
Morphine
Ondanosterone
Tramadol
9. Antiparkinsonism medicines
Amantadine
Apomorphine
Benzhexol
Biperiden
Entacapone
levodopa + carbidopa
Procyclidine
Ropinirol
Selegiline
10. Medicines affecting the blood
10.1 Antianaemia medicines
Ferrous salt
Ferrous salt + folic acid
CC
CC
SS
C
S
B
CC
C
C
CC
C
S
AA
AA
tablet, 15 mg ,30 mg (sulfate)injection,10 mg (sulfate or hydrochloride) in 1-mlampoule
tablet, 4mg, 8 mg (as hydrochloride)injection, 2mg /ml (as hydrochloride) in 2-ml ; 4-ml ampoule
capsule, 50 mg (hydrochloride)Injection, 50mg/ml (hydrochloride) in 2-ml ampoule
capsule, 100 mg
injection, 20 mg/ml in 2-ml ampoule
tablet, 2mg, 5mg ( hydrochloride )
tablet, 2 mg (hydrochloride)injection, 5 mg ( lactate) in 1-ml ampoule
tablet, 200 mg
tablet, 100 mg + 10 mg, 250 mg + 25 mg
tablet, 5 mg (hydrochloride)injection, 5 mg/ml (hydrochloride) in 2-ml ampoule
tablet, 0.25 mg, 1 mg, 2mg, 5 mg
tablet, 5 mg ( hydrochloride )
tablet , equivalent to 60 mg ironoral solution, equivalent to 25 mg iron ( as sulfate )/ml
tablet, equivalent to 60 mg iron + 400 micrograms folic acid
19
Medicine Route of administration, dosageforms and strengths
Level ofUse
Folic acid
Hydroxocobalamin
Iron dextran
Iron sorbitol
10.2. Medicines affecting coagulation
Desmopressin
Heparin sodium
Phenindione
Phytomenadione
Protamine sulphate
Warfarin
11. Blood products and plasma substitutes:
11.1. Plasma substitutes
Dextran 70
Dextran 40
Human albumin
ACC
C
B
B
CC
C
S
CC
C
C
B
B
B
tablet, 5 mgtablet, 1 mginjection, 15 mg/ml in 1-ml ampoule
injection, 1 mg in 1-ml ampoule
injection, equivalent to 50 mg,1mg iron/ml in 2-mlampoule
injection , equivalent to 1 mg iron/ml in 50-mlampoule
injection, 4 microgram (acetate) in I-ml ampoulenasal spray, 10 microgram (acetate)/metered dose
injection, 1 000 IU ,5 000 IU/ ml, and 20 000 IU in1-ml ampoule
tablet, 10 mg, 25 mg , 50 mg
tablets, 10mginjection, 10mg/ml in 5-ml ampoule
injection, 10 mg/ml in 5-ml ampoule
tablet, 1 mg , 2 mg, 3mg and 5 mg (sodium salt)
injectable solution, 6 %
injectable solution, 10%
solution containing from 4 to 5% albumin orconcentrated solution containing 20 to 25%albumin
20
Medicine Route of administration, dosageforms and strengths
Level ofUse
Polygeline
11.2. Plasma Fractions for specific use:
Factor VIIa(recombinant)
Factor VIIIconcentrate
Factor VIIIrecombinant
Factor IX Complex(coagulation factor II,VII, IX, X ) concentrate
Plasma, human
12. Cardiovascular medicines
12.1. Anti-anginal medicines
Amlodipine
Atenolol
Diltiazem
Glyceryl trinitrate
Isosorbide dinitrate
Isosorbide mononitrate
Nifedipine
B
B
B
B
B
B
C
B
C
BCCC
CBB
B
B
injectable solution, 3.5 %
dried
dried
dried
dried
fresh frozen
tablet, 5mg, 10 mg
tablet, 50, 100 mg
tablet, 60 mg (hydrochloride)
tablet, (sublingual) 5 mgtransdermal, 5 mginjection, 1 mg/ml in 1-ml ampouleaerosol spray, 200 microgram / metered dose
tablet, (sublingual) 5 mgtables, 10 mg, 20mg, 40mginjection, 1 mg/ml
tablet, 10mg, 20mg, 40 mg
capsule or tablet, 10 mg, 20mg, 40 mg
21
Medicine Route of administration, dosageforms and strengths
Level ofUse
Propranolol
Verapamil
12.2. Anti-arrhythmic medicines
Adenosine
Amiodarone
Atenolol
Bretylium tosilate
Disopyramide
Esmolol
Flecainide acetate
Isoprenaline
Lidocaine
Mexiletine
Procainamide
Propafenon
Propranolol
BC
C
S
CS
B
S
CS
S
SS
C
S
SS
CS
S
BC
tablets, 10 mg, 40 mg (hydrochloride)injection, 1 mg (hydrochloride) in 1-ml ampoule
tablet, 40 mg, 80 mg ( hydrochloride)
injection, 3 mg/ml in 2-ml vial
tablet, 100 mg, 200 mg (hydrochloride)injection, 50mg (hydrochloride)/ml in 3-ml ampoule
tablet, 50 mg, 100 mg
injection, 50 mg/ml in 10-ml ampoule
capsule or tablet, 100 mg (as phosphate)injection, 10 mg/ml (as phosphate)
injection, 10 mg/ml in 10ml vial
tablet, 50 mginjection, 10 mg/ml in 15-ml ampoule
injection, 1 mg/ml; 20 microgram/ml (hydrochloride)in 2-ml ampoule
injection, 20 mg (hydrochloride)/ml in 5-ml ampoule
capsule, 50 mg, 200 mg (hydrochloride)injection, 25 mg/ml (hydrochloride) in 10-ml ampoule
tablet, 250mg (hydrochloride)injection, 100 mg (hydrochloride)/ml in 10-ml ampoule
tablet, 150 mg, 300 mg (hydrochloride)
tablet, 10 mg, 40 mg (hydrochloride)injection, 1 mg (hydrochloride) in 1-ml ampoule
22
Medicine Route of administration, dosageforms and strengths
Level ofUse
Quinidine
Tocainide
Verapamil
12.3. Antihypertensive medicines
Atenolol
Captopril
Diazoxide
Doxazosin
Enalapril
Hydralazine
Hydralazine +Reserpine
Hydrochlorothiazide
Indolol + clopamide
Lisinopril
Losartan potassium
Methyldopa
Minoxidil
Nifedipine
S
S
BS
B
BC
S
S
C
CC
C
B
C
C
C
B
C
BB
tablet, 200 mg (sulfate)
tablet, 400 mg (hydrochloride)
tablet, 40 mg,80mg (hydrochloride)injection, 2.5 mg (hydrochloride)/ml in 2-ml ampoule
tablet, 50, 100 mg
scored tablet, 25 mgscored tablet, 50 mg
injection, 15 mg/ml in 20-ml ampoule
tablet, 2 mg, 4 mg (as mesilate)
tablet, 2.5 mg
tablet, 25mg ,50 mg (hydrochloride)powder for injection, 20 mg (hydrochloride) in ampoule
tablet, 10 mg + 100 microgram
scored tablet, 25mg ,50 mg
tablet, 10 mg + 5 mg
tablet, 5mg, 10mg ,20 mg
tablet, 25 mg, 50 mg
tablet, 250 mg
scored tablet, 2.5 mg
capsule or tablet, 10 mgcapsule or tablet, long acting 20 mg, 40 mg
23
Medicine Route of administration, dosageforms and strengths
Level ofUse
Perindopril
Phentolamine mesilate
Prazosin
Propranolol
Reserpine
Sodium nitroprusside
Valsartan
Verapamil
Potassium channel activator
Nicorandil
Central and peripheral vasodilator
Cinnarizine
Oxpentoifyllin
Phosphodiesterase inhibitor
Enoximone
Milrinone
12.4. Medicines used in heart failure and vascular shock
Digoxin
C
S
B
B
CC
S
C
CS
C
CC
S
S
S
BBB
tablet, 2 mg
injection, 10 mg/ml in 1-ml ampoule
tablet, 500 mg (hydrochloride)
tablet, 40 mg, 80 mg (hydrochloride)
tablet, 100 microgram, 250 microgram,injection, 1 mg in 1-ml ampoule
powder for infusion, 50 mg in ampoule
capsule, 40mg , 80 mg
tablet, 40 mg, 80mg (hydrochloride)injection, 2.5 mg(hydrochloride) /ml in 2-ml ampoule
tablet, 10 mg
tablet, 25 mg ,capsule, 75 mg
tablet, 400 mg
injection, 5mg/ml
injection,1mg/ml
tablet, 62.5 microgram, 250 microgramoral solution, 50 microgram/mlinjection, 250 microgram/ml in 2-ml ampoule
24
Medicine Route of administration, dosageforms and strengths
Level ofUse
Phentolamine
Medicines used in vascular shock
Captopril
Digoxin
Dobutamine
Dopamine
Ephedrine
Metaraminol
12.5. Antithrombotic medicines
Acetyl salicylic acid
Alteplase
Clopidogrel
Dipyridamole
Streptokinase
Ticlopidine
Tirofiban
Cardiac pulmonary resuscitation
Atropine
S
B
BC
C
S
C
S
S
B
S
C
C
S
C
S
B
injection, 10 mg(mesilate)/ml
scored tablet, 25 mg
tablet, 62.5 microgram, 250 micrograminjection, 250 microgram/ml in 2-ml ampoule
concentrate for intravenous infusion, 12.5 %(hydrochloride) for dilution before useinjection, 50 mg/ml
concentrate for intravenous infusion, 40 mg (hydrochloride) /ml in 5-ml vial
injection, 3 mg(as hydrochloride) /ml
injection, 10 mg (as tartrate)/ml ampoule
tablet, 75 mg,100 mg
injection powder for reconstitution,10 mg/ vial
tablet, 75 mg (as hydrogen sulphate)
tablet, 25 mg
powder for injection, 1.5 million IU in vial
tablet, 250 mg (hydrochloride)
concentrate for intravenous infusion, 250microgram/ml (as hydrochloride) for dilutionbefore use in 50-ml vial
injection, 600 microgram/ml
25
Medicine Route of administration, dosageforms and strengths
Level ofUse
Epinephrine(adrenaline)
Calcium gluconate
Potassium chloride
Sodium hydrogencarbonate
Beta-adrenoceptor blocking drugs
Atenolol
Carvedilol
Cinnarizine
Dobutamine
Ephedrine
Indolol+clopamide
Labetalol
Metoprolol
Nicorandil
Noradrenaline
Oxpentifyllin
Pindolol
Propranolol
S
C
C
C
BS
C
CC
S
S
C
C
C
C
S
S
C
BS
injection,100microgram (as hydrochloride orhydrogen tartrate)/ml in 10-ml ampoule
injection, 10% in 10-ml ampoule
concentrate for intravenous infusion 15% fordilution before use in 10-ml ampoule
injectable solution 8.4% in 10-ml ampoule
tablet, 50mg , 100 mginjection, 500 microgram/ml
tablet, 6.25mg, 12.5mg, 25mg
tablet, 25 mgcapsule, 75 mg
injection, 50 mg/ml
injection, 3 mg(as hydrochloride)/ml
tablet, 5 mg+ 10 mg
injection, 5 mg , 50 mg , 100 mg (hydrochloride)/ml
tablet, 50 mg
tablet, 10 mg
injection, 200 microgram (acid tartrate)/ml
tablet, 400 mg
scored tablet, 5 mg
tablet, 10 mg, 40 mg,160 mg (hydrochloride)injection, 1 mg (hydrochloride) in 1-ml ampoule
26
Medicine Route of administration, dosageforms and strengths
Level ofUse
Sotalol
Xamoterol
Narcotic analgesics
Morphine
Pethidine
Medicines used in ICU
Labetalol
Metaraminol
Noradrenaline
12.6 Lipid regulating medicines
Fibrates
Bezafibrate
Ciprofibrate
Clofibrate
Statins
Atorvastatin
Fluvastatin
Pravastatin
Simvastatin
13. Dermatological medicines
C
S
S
S
S
S
S
C
C
C
C
C
C
C
tablet, 80 mg (hydrochloride)
tablet, 200 mg
injection, 10 mg (sulfate or hydrochloride) in 1-mlampoule
injection, 50 mg/ml
injection, 5 mg/ml in 4-ml ampoule
injection, 10 mg (as tartarate)/ml in 1-ml ampoule
injection, 1 mg/ml (as acid tartarate) in 2-mlampoule for dilution before use
tablet, 200 mg
tablet, 100 mg
tablet
tablet, 10 mg, 20 mg (as calcium trihydrate)
capsule, 20 mg, 40 mg (as sodium salt)
tablet, 10mg, 20 mg (pravastatin sodium)
tablet, 10 mg, 20 mg
27
Medicine Route of administration, dosageforms and strengths
Level ofUse
13.1. Antifungal medicines
Benzoic acid +Salicylic Acid
Ketoconazole
Miconazole
Nystatin
Selenium sulfide
Sodium thiosulfate
13.2. Anti-infective medicines
Aciclovir
Fusidic acid
Griseofulvin
Ketoconazole
Methylrosanilinium Chloride(Gentian violet)
Neomycin+BacitracinB
Polymixin + Neomycin
Potassium permanganate
Silver sulfadiazine
Terpinafine
A
B
A
B
B
B
B
A
B
C
AA
C
CC
A
A
CC
ointment or cream, 6 % + 3%
cream
ointment or cream, 2 % (nitrate)
ointment or cream, 100 000 IU/gm
detergent base suspension, 2%
solution 15%
capsule or tablet, 200 mg
ointment, 2 %
capsule or tablet, 125 mg, 250 mg
scored tablet, 200 mg
aqueous solution or tincture, 0.5 %
ointment, 5mg (sulphate)+ 500 IU (zinc)/ g
powderointment
aqueous solution, 1 : 10 000
cream, 1 %, in 500g container
tablet, 250mg (as hydrochloride)cream, 1 % (hydrochloride)
28
Medicine Route of administration, dosageforms and strengths
Level ofUse
Tetracycline
13.3. Anti-inflammatory and antipruritis medicines
Betamethasone
Calamine lotion
Clobetasol proprionate
Hydrocortisone
Zinc oxide
13.4. Astringents medicines
Aluminium diacetate
13.5. Keratoplastic and keratolytic agents
Benzoyl peroxide
Coal tar
Dithranol
Flurouracil
Lactic acid
Podophyllum resin
Salicylic acid
13.6. Scabicides and pediculicides
Benzyl benzoate
AA
C
B
C
B
A
C
C
B
C
C
C
C
BC
AA
cream or ointment, 3 % (hydrochloride)
cream or ointment, 0.1 % (as valerate)
lotion, 15 % compound
cream or ointment, 0.05 %
cream or ointment, 1 % (acetate)
ointment, 15 %
solution, 13 % for dilution
cream or lotion, 5 %
solution topical, 5 %
ointment, 0.1- 2 %
ointment, 5 %
cream or ointment
solution topical, 10 - 25 %
solution topical, 5%ointment, 10 %
lotion, 25 %
29
Medicine Route of administration, dosageforms and strengths
Level ofUse
Malathion
Permethrin
Sulfur
13.7. Other dermatological agents
Dapsone
Methoxsalen
14. Diagnostic agents
14.1. Ophthalmic
Fluorescein
Rose bangal
Tropicamide
14.2. Radiocontrast media
Amidotrizoate
Barium sulfate
Gadolimium-DTPA
Iohexol
Iopamidol
Iopanoic acid
Iopromide
A
BB
B
C
CC
CC
CC
C
C
C
C
C
C
C
C
liquid or cream or topical preparations, 0.5 %
cream, 5 %lotion, 1 %
ointment or cream,10 %
tablet, 50 mg, 100 mg
tablet, 10 mgpaint
eye drops, 1 % (sodium salt)strip of 1 % solution
eye drops, 1 % (sodium salt)strip of 1 % solution
eye drops, 0.5 %
injection
aqueous suspension, 50 %w/v
injection, 469 mg/ml
injection, 140 - 350 mg/ml in 10-ml and 20-ml ampoule
injection, 300 mg/ml
tablet, 500 mg
injection, 300mg/ml, in 20-ml ampoule, 50-ml vial.
30
Medicine Route of administration, dosageforms and strengths
Level ofUse
Iotrolan
Propyliodone
Urografin76%
15. Disinfectants and antiseptics
Chlorine-basecompound
Chlorohexidine
Chloroxylenol
Ethanol
Glutaral
Hydrogen peroxide
Iodine
Potassiumpermanganate
Povidone iodine
16. Diuretics
Amiloride
Bendroflumethiazide
Bumetanide
Furosemide
C
C
C
B
AA
B
B
B
B
A
B
B
B
B
B
BB
injection, 300 mg/ml
oily suspension, 500 mg/ml ,600 mg/ml in 20-mlampoule
aqueous solution, meglumine diatrizoate 66% w/v+sodium diatrizoate 10% w/v in 50 & 100-ml bottle
powder, (0.1%available chlorine) for solution
solution, 5% (digluconate) concentrated for dilution
solution, 4.8%
solution, 70%(denature)
solution, 2%
solution, 3 %
solution, 2.5 %
aqueous solution, 1: 10 000
solution, 10%
tablet, 5 mg (hydrochloride)
tablet, 50 mg
tablet, 1 mg
tablet, 40 mg, 250 mginjection, 10 mg/ml in 2-ml ampoule
31
Medicine Route of administration, dosageforms and strengths
Level ofUse
Hydrochlorothiazide
Mannitol
Metolazone
Spironolactone
17. Gastrointestinal medicines
17.1. Antacids and other antiulcer medicines
Aluminium hydroxide + Magnesium hydroxide
Cimetidine
Omeprazole
Ranitidine
17.2. Antiemetic medicines
Domperidone
Metoclopramide
Promethazine
17.3. Anti-inflammatory medicines
Anti-haemorrhoidalmedicine(local anaesthetic+ astringent +anti-inflammatory medicine)
B
S
B
B
AAAA
BC
C
BBB
C
BB
AAA
B
tablet, 25 mg, 50 mg
injectable solution, 10 %, 20 %
tablet, 5mg
tablet, 25mg, 50 mg
oral suspension, 200 mg +200 mg/5 mltablet, 200mg+200mg
tablet, 200 mginjection, 100 mg/ml in 2-ml ampoule
capsule, 10mg, 20 mg
tablet, 150 mg, 300 mg ( as hydrochloride)oral solution, 75mg/5-mlinjection, 25mg/ml in 2-ml ampoule
tablet, 10 mg (as maleate)
tablet, 10 mg ( hydrochloride)injection, 5 mg (hydrochloride)/ml in 2-ml ampoule
tablet, 10mg, 25 mg (hydrochloride)elixir or syrup, 5mg (hydrochloride)/5-mlinjection, 25 mg (hydrochloride)/ml in 2-ml ampoule
ointment or suppository
32
Medicine Route of administration, dosageforms and strengths
Level ofUse
Hydrocortisone
Prednisolone
Sulfasalazine
17.4. Laxatives
Bisacodyl
Bran
Fibrous preparations
Lactulose
Magnesium sulfate
Senna
17.5 Medicines used in diarrhea
17.5.1 Oral rehydration
Oral rehydration salt (for glucose-electrolytesolution)
17.5.2 Medicines for diarrhea in children
Zinc sulfate
17.5.3. Antidiarrhoeal (symptomatic medicines)
Diphenoxylatehydrochloride+atropine sulfate
BB
B
CCC
B
AA
B
C
B
AA
AA
B
B
suppository,25mg (acetate)retention enema
enema
tablet, 500retention enemasuppository, 500 mg
tablet, 5mg
powder
granules
solution or syrup, 3.35 mg/5ml
powder, 5 – 50 gm
tablet, 7.5 mg (sennosides)
dry mixture (WHO formula) in sachet for I liter ofelectrolyte solution
tablet or syrup 10 mg in unit dosage form
tablet, 2.5 mg +25 microgram
33
Medicine Route of administration, dosageforms and strengths
Level ofUse
Loperamide
17.6. Antispasmodic medicines
Atropine
Hyoscine butyl bromide
Mebeverine
17.7 Medicines acting on liver, gall bladder & pancreas
Cholestyramine powder
Ethanolamine oleate
Hepatitis Bimmunoglobulin (HBIG)
Lamivudine
Phytomenadione
Vasopressin
18. Hormones, other endocrine medicines and contraceptive
18.1. adrenal hormones and synthetic substituents
Dexamethasone
Fludrocortisone
Hydrocortisone
Prednisolone
A
B
AA
C
C
S
S
S
B
C
CC
C
CB
B
tablet, 2 mg (hydrochloride)
tablet, 600 microgram (sulfate)
tablet, 10 mginjection, 20 mg / ml in 1-ml ampoule
tablet, 135 mg (hydrochloride)
powder, 4 g/ sachet
injection, 5% in 5-ml ampoule
injection, 500 units
tablet, 100mg
injection, 10 mg/ml in 5-ml ampoule
injection, 20 units/ml in 1-ml ampoule
tablet, 500 micrograminjection, 4 mg (as sodium phosphate) in 1-ml ampoule
tablet, 50 microgram, 100 microgram(acetate)
tablet, 20 mg powder for injection, 100 mg (as sodium succinate)in vial
tablet, 1 mg, 5mg
34
Medicine Route of administration, dosageforms and strengths
Level ofUse
18.2. Androgens
Testosterone
Tetracosactrin(ACTH analogue)
18.3. Contraceptives
Hormonal contraceptives
Ethinylestradiol +Levonorgestrel
Ethinylestradiol + Norethisterone
Levonorgestrel
Medroxyprogesteroneacetate
Norethisterone
Norethisterone enantate
18.4. Estrogens
Ethinylestradiol
Ethinylestradiol +Progesterone
18.5. Insulins and other antidiabetic agents
C
C
B
B
CB
CC
B
B
CSSS
C
injection, 200 mg (enantate) in 1-ml ampoule
injection, 250 microgram/ml in 1-ml ampoule
tablet, 30 microgram + 150 microgram,30 microgram + 250 microgram, 50 microgram+ 250 microgram
tablet, 35 microgram + 1.0 mg
tablet, 30 microgram tablet, 750 microgram (pack of two), 1.5 microgram
depot injection, 150 mg/ml in 1-ml vialinjection, 50 mg/ml in 3-ml vial
tablet, 5 mg
oily solution, 200 mg/ml in 1-ml ampoule
tablet, , 10 microgram, 50 microgramtablet, 2 mggel, creamimplant
tablet
35
Medicine Route of administration, dosageforms and strengths
Level ofUse
Glibenclamide
Metformin
Insulin injection(soluble)
Intermediate-acting insulin
18.6. Ovulation inducers
Clomifene
18.7. Progesterones
Medroxyprogesteroneacetate
Norethisterone
18.8. Thyroid hormones and antithyroid medicines
Carbimazole
Levothyroxine
Potassium iodide
Propylthiouracil
18.9. Other endocrine related medicines
Alphacalciferol (one alpha)
Bromocriptine
Chorionicgonadotrophin
B
B
B
B
S
C
C
B
B
B
S
S
C
S
tablet, 2.5 mg, 5 mg
tablet, 500 mg (hydrochloride)
injection, 40 IU/ml, 100 IU/ml in 10-ml vial
injection, 40 IU/ml, 100 IU/ml in 10-ml vial (ascompound insulin zinc suspension or isophaneinsulin)
tablet, 50 mg (citrate)
tablet, 5 mg
tablet, 5 mg
tablet, 5 mg
tablet, 50 microgram, 100 microgram (sodium salt)
tablet, 60 mg
tablet, 50 mg
tablet, 0.25 microgram , 1 microgram
tablet, 2.5 mg (as mesylate)
powder for injection, 500 unit ampoule
36
Medicine Route of administration, dosageforms and strengths
Level ofUse
Cyproterone acetate
Danazol
Desmopressin
Vasopressin
Cabergoline (dopamine agonist)
Dydrogesterone
Erythrobioten
Gn Rh agonist
Gn Rh antagonist Human menopausal gonadotrophin
Misoprostol (synthetic prostaglandin E1 analogue)
Prostaglandin E2
Purified FSH/ human(meopausal urine)
Recombinant FSH (genetically engineered)
Tamoxifen
S
C
C
C
S
C
S
SSS
S
S
CC
CC
S
S
S
tablet, 50 mg
capsule, 200 mg
intranasal solution, 100 microgram/ml
injection, 20 IU in 1–ml ampoule
tablet, 0.5 mg
tablet, 10 mg
injection, 2 000 IU, 4 000 IU
intranasal, 10 gm solution.intramuscular, 3.75 mg, 3.6 mgsubcutaneous, 0.1mg
subcutaneous, 0.25 mg ,3mg
injection, 75 IU FSH/ 75 LH
oral tablet, 50 mgvaginal tablet, 50 mg
vaginal tablet, 3 mggel
injection, 75 IU
subcutaneous injection, 50 IU,100 IU, 150 IU,300IU,600 IU.
tablet, 10 mg
37
Medicine Route of administration, dosageforms and strengths
Level ofUse
Tranexamic acid
19. Immunologicals All immunologicals should comply with World Health Organization requirements
19.1. Diagnostic agents
Tuberculin, purified protein derivative (PPD)
19.2. Sera and immunoglobulins
Anti-D immunoglobulin
Anti – D immunoglobulin (human)
Anti scorpion sera
Antitetanusimmunoglobin (human)
Anti-venom sera
Diphtheria antitoxin
Gas gangrene antitoxin
Immunoglobulin, human normal
Rabies immunoglobulin
19.3. Vaccines (strength and level of use as decided by FederalMinistry of Health)
19.3.1. For universal immunization
BCG Vaccine
C
B
B
B
B
B
B
B
C
B
B
AA
tablet, 250 mg, 500 mg
injection, solution : 5TU/0.1ml in 1-ml ampoule( WHO standard )
injection, 250, 500 units
injection, 250 microgram /ml (in single dose vial)
injection, locally defined type
injection, 500 IU in vial
injection, locally defined type
injection, 10 000 IU , 20 000 IU in vial
injection
injection, (intramuscular, intravenous)
injection, 150 IU/ ml in vial
injection
38
Medicine Route of administration, dosageforms and strengths
Level ofUse
Diphtheria –pertussis – tetanusvaccine
Measles vaccine (live attenuated)
Measles – mumps – rubella vaccine
Poliomyelitis vaccine
Tetanus vaccine
Diphtheria vaccine
Pertussis vaccine
19.3.2. For specific group of individuals
Hepatitis B vaccine
Influenza vaccine
meningococcal vaccine
Mumps vaccine
Rabies vaccine
Rubella vaccine
Typhoid vaccine
Yellow fever vaccine
20.Muscle relaxants
Alcuronium
Atracurium
AA
AA
AA
AA
AA
AA
AA
AA
AA
AA
AA
AA
AA
AA
AA
C
C
injection
injection
injection
orally
injection
injection
injection
injection
injection
injection, 5 mg (chloride)/ml in 2- ml ampoule
injection, 5 mg (besylate)/ml in 2-ml ampoule
39
Medicine Route of administration, dosageforms and strengths
Level ofUse
Neostigmine
Pancuronium
Pyridostigmine
Suxamethonium
Tubocurarine
Vecuronium bromide
21.Ophthalmological preparations
21.1.Anti-infective agents
Aciclovir
Benzylpenicillin
Chloramphenicol
Gentamicin
Idoxuridine
Sulfacetamide
Tetracycline
21.2. Anti- inflammatory agents
Prednisolone
BC
C
CC
CC
C
C
C
B
AA
A
CC
AA
AA
B
tablet,15 mg (bromide)injection, 500 microgram, 2.5 mg (metilsulfate) in1-ml ampoule
injection, 2 mg (bromide)/ml in 2-ml ampoule
tablet, 60 mg (bromide)injection, 1 mg (bromide) in 1-ml ampoule
injection, 50 mg (chloride)/ml in 2-ml ampoulepowder for injection, 500 mg in 10-ml vial
powder for injection, 10 mg (chloride)/ml in 1.5-mlampoule
powder for injection, 10 mg (bromide) in vial
eye ointment, 3 %
powder for preparation of eye drops, 1.5 mg/ml(2 500 IU/ ml)
solution (eye drops), 0.5 % ointment, 1 %
solution (eye drops), 0.3 % (sulfate)
solution (eye drops) ,0.1%eye ointment, 0.2 %
solution (eye drops), 15 % (sodium salt)
eye ointment, 1 % (hydrochloride)
solution (eye drops), 0.5 % (sodium phosphate)
40
Medicine Route of administration, dosageforms and strengths
Level ofUse
21.3. Local anaes-thetics
Tetracaine
21.4. Miotics and antiglucoma medicines
Acetazolamide
Pilocarpine
Timolol
21.5. Mydriatics and cyclopllegics
Atropine
Cyclopentolate
Epinephrine (adrenaline )
Homatropine
Phenylepherine
Tropicamide
21. 6. Anti-allergic medicines
Antazoline
21.7. Other ophthalmic preparations
Acetylcystine
Sodium cromoglicate
22. Oxytocics and antioxytocic
A
BC
C
C
C
C
C
C
S
C
B
S
C
solution (eye drops), 0.5 % (hydrochloride)
tablet, 250 mgpowder for injection, 500 mg (as sodium salt) in vial
solution (eye drops), 2%, 4% (hydrochloride ornitrate)
solution (eye drops), 0.25 %, 0. 5 (as maleate)
solution (eye drops), 0.1 %, 0.5 % , 1 % (sulfate)
solution (eye drops), 0.5 % (hydrochloride)
solution, (eye drops) 2 % (as hydrochloride)
solution (eye drops), 1 % (hydrobromide)
solution (eye drops), 10 % (hydrochloride)
solution (eye drops), 0.5%, 1 %
solution (eye drops), 0.5 % (hydrochloride)
solution (eye drops), 5 %
solution (eye drops), 2 %
41
Medicine Route of administration, dosageforms and strengths
Level ofUse
Oxytocics
Ergometrine
Oxytocin
Anti-oxytocic
Nifedipine
Salbutamol
23. Dialysis solution
Haemodialysis solution
Intraperitonealdialysis solution
24. Pyschotherapeutic medicines
24.1.Medicines used in Psychotic disorders
Chlorpromazine
Clozapine
Fluphenazine
Flupenthixol
Haloperidol
AA
B
C
BC
S
S
BCBB
C
C
C
C
tablet, 200 microgram (hydrogen maleate)injection, 200 microgram (hydrogen maleate) in 1-ml ampoule
injection, 10 IU in 1-ml ampoule
immediate release capsule, 10 mg
tablet, 4 mg, (as sulfate)injection, 50 microgram (as sulfate)/ml in 5-mlampoule
parenteral solution, concentrated (of appropriatecomposition)
parenteral solution, (of appropriate composition)
tablet, 25 mg (hydrochloride)tablet, 100 mg (hydrochloride)injection, 25 mg (hydrochloride)/ml in 2-ml ampoulesyrup, 25 mg (hydrochloride)/5ml
scored tablet, 25 mg, 50 mg, 100 mg
injection, 25 mg/ml (decanoate or enantate) in 1-mlampoule
injection, 20 mg/ml (decanoate) in 1-ml ampoule
scored tablet, 2 mg, 5 mg
42
Medicine Route of administration, dosageforms and strengths
Level ofUse
Olanzapine
Risperidone
Trifluoperazine
Zuclopenthioxol
24.2.Medicines used in mood disorders
24.2.1 Medicines used in depressive disorders
Amitriptyline
Citalopram
Clomipramine
Fluoxetine
Fluvoxamine
Imipramine
Mianserin
Paroxetine
Phenelzine
24.2.2 .Medicines used in bipolar disorders
Carbamezapine
C
CC
CS
C
CC
B
C
B
C
C
B
C
C
S
CC
injection, 5 mg/ml in 1-ml ampoule
tablet, 5 mg, 10 mgpowder for injection, 5 mg/ml in 10 mg vial
tablet, 2 mg, 4 mgdepot injection, powder for reconstitution 25 mg invial (with diluent )
tablet, 1 mg, 5 mg (as hydrochloride)
injection, 50 mg(as acetate)/ml in 1-ml ampouledepot injection, 200 mg/ml in 1-ml ampoule (asdeconoate)
tablet, 10 mg, 25mg (hydrochloride)
tablet, 10mg, 20 mg (as hydrochloride)
tablet, 10mg, 25mg (hydrochloride)
capsule, 20mg , 60mg (as hydrochloride)
tablet, 50 mg, 100 mg (maleate)
tablet, 10 mg, 25 mg (hydrochloride)
tablet, 30 mg (hydrochloride)
tablet, 20 mg (as hydrochloride)
tablet, 15 mg (as sulfate)
scored tablet, 100 mg, 200 mgsyrup, 100 mg/5ml
43
Medicine Route of administration, dosageforms and strengths
Level ofUse
Lithium carbonate
Valproic acid
24.3. Medicines used in generalised anxiety and sleep disorders
Bromazepam
Buspirone
Chloral hydrate
Chlordiazepoxide
Diazepam
Lorazepam
Nitrazepam
Zolpidem tartrate
24.4. Medicines used for obsessive compulsive disorders andpanic attack
Clomepramine
24.5.Medicines used in child psychiatric disorder
Clonazepam
Methyl phenidate
25. Medicines acting on the respiratory tract
25.1. Anti-asthmatic and medicines for chronic obstructive pul-monary disease
Aminophylline
SC
C
C
C
A
C
BB
CC
B
C
B
C
S
B
capsule or tablet, 300 mgcapsule or tablet, 200 mg, 400 mg
enteric coated tablet, 200 mg, 500 mg (sodium salt)
tablet, 1.5 mg, 3 mg, 6 mg
tablet, 5 mg, 10 mg
syrup, 200 mg/5ml
tablet, 5 mg, 10 mg
scored tablet, 2 mg, 5 mginjection, 5 mg/ml in 2-ml ampoule
tablet, 1 mg, 2 mginjection, 4 mg/ml
tablet, 5 mg
tablet, 10 mg
capsule, 10 mg, 25 mg (hydrochloride)
tablet, 0.25 mg, 0.5 mg, 2 mg
tablet, 10 mg
tablet, 200 mg
44
Medicine Route of administration, dosageforms and strengths
Level ofUse
Beclometasone
Cromoglicic acid
Ipratropium bromide
Ketotifen
Salbutamol
B
A
AA
C
C
Salmetrol
Theophylline
26. Solutions correcting water , electrolyte and acid-basedisturbances
26.1 Oral
Oral rehydration salt
Potassium chloride
26.2 Parenteral
Calcium chloride
B
C
B
B
C
AA
B
A
AA
C
C
C
B
AA
B
C
injection, 25 mg/ml in 10-ml ampoule
inhalation (aerosol), 50 microgram, 250 microgram(diproprionate)/dose
inhalation (aerosol), 20mg (sodium salt)/dose
inhalation(aerosol), 20 microgram /dose
syrup, 1 mg (hydrogen fumarate)/5ml
tablet, 2 mg,4mg (as sulfate)
inhalation (aerosol), 100 microgram (as sulfate) /dose
* IMCI, pre referral treatment
syrup, 2 mg (as sulfate)/5ml
respirator solution, for use in nebulizers, 5 mg (as
sulfate)/ml
injection, 50 microgram (as sulfate) /ml in 5-ml ampoule
inhalation (aerosol), 25 microgram /dose
tablet, 100mg, 200mg, 300mg
powder in sachet to prepare one liter of solution , forcomposition see section 17.5.1
powder for solution
injection, 100 mg/ml in 10-ml ampoule
45
Medicine Route of administration, dosageforms and strengths
Level ofUse
C
B
B
B
B
C
C
C
B
C
AA
AA
C
SS
B
B
Calcium gluconate
Glucose
Glucose with sodiumchloride
B
B
Potassium chloride
Sodium hydrogen carbonate
C
Sodium chloride
Sodium lactate compound solution
26.3 Miscellaneous
Water for injection
27.Vitamins and minerals
Ascorbic acid
Calcium gluconate
Ergocalciferol
Iodine
injection, 100 mg/ml in 10-ml ampoule
injectable solution , 5%, 10% isotonic, 50% hypertonic
injectable solution, 4% glucose, 0.18% sodium chlo-ride (equivalent to Na+ 30 mmol/L, Cl- 30 mmol/L.
injectable solution, 5% glucose, 0.45% sodium chloride
injectable solution, 5% glucose, 0.9% sodium chloride
solution, 11.2 % in 20-ml ampoule (equivalent to K+
1.5 mmol/ml, Cl- 1.5 mmol/ml)
injectable solution, 8.4% In 50-ml ampoule(= to Na+ 1000 mmol/l, HCO3
- 1000 mmol/l)
injectable solution, 1.4% In 50-ml ampoule(= to Na+ 167 mmol/l, HCO3
- 167 mmol/l)
injectable solution, 0.9% isotonic(equivalent to Na+ 154 mmol/l, Cl- 154 mmol/l)
injectable solution
2-ml , 5-ml ampoules
tablet, 50 mg
injection,100 mg/ml in10-ml ampoule
capsule or tablet, 1.25 mg (50 000 IU)oral solution, 250 microgram/ml( 10000/ml)
iodized oil, 1 ml (480 mg iodine), 0.5 ml (240 mgiodine) in ampoule (oral or injectable), 0.57 ml, (308mg iodine) in dispenser bottlecapsule, 200 mg
46
Medicine Route of administration, dosageforms and strengths
Level ofUse
Nicotinamide
Pyridoxine
Retinol
B
B
A
Riboflavin
Sodium fluoride
Thiamine
A
28. Medicines acting on the ear, nose and oropharynx
28.1. Medicines acting on the ear ( topical)
28.1.1 Anti-inflammatory and anti-infective preparations
Chloramphenicol
Clotrimazole
Dexamethasone +framycetin sulphate +gramicidin
Flumetazonepivalate + clioquinol
Gentamicin
Hydrocortisone + clioquinol
B
B
B
B
B
AB
B
C
B
B
C
C
C
C
B
tablet, 50 mg
tablet, 25 mg ( hydrochloride )
sugar-coated tablet , 10 000 IU ( 5.5 mg) ( as palmitate)
capsule , 200 000 IU (110 mg) ( as palmitate)
oral oily solution, 100 000 IU( as palmitate)
/ml in multidose dispenser
* IMCIwater miscible injection, 10 000 IU (as palmitate)(55 mg) in 2-ml ampoule
tablet, 5 mg
in any appropriate topical formulation
tablet, 50 mg ( hydrochloride)
ear drops , 5%
ear drops, 1 %
ear drops, 0.05 % +0.5 % + 0.005 %
ear drops, 0.02 % +1%
ear drops, 0.3% (as sulfate)
ear drops, 1.5% ( acetate) + 1%
47
Medicine Route of administration, dosageforms and strengths
Level ofUse
Neomycin + Hydrocortisone
Nystatin+ neomycin+ gramicidin + triamcinolone acetonide
PolymyxinB sulfate+ Neomycin sulfate+ Hydrocortisone
28.2. Medicines acting on the nose ( topical)
28.2.1 Nasal decongestants ( topical)
Beclomethasone
Ephedrine
Ephedrinehydrochloridel+ naphazoline
Xylometazoline
28.2.2 Antihistamines (systemic)
Betahistine
Chlorphenamine
Cinnarazine
Clemastine
Prochlorperazine
28.3. Medicines acting on the oropharynx (topical)
B
C
C
C
B
C
C
C
C
CC
C
C
ear drops ,0.5% (sulfate) + 1.5% (acetate)
ear ointment 100 000 unit +0.25% + 0.025% +0.1%
ear drops,10 000 units + 3400 units + 1%
nasal spray, 50 microgram(dipropionate) /metered spray
nasal drops ,0.5%, 1%(hydrochloride)
nasal drops, 0.5% +0.125%
nasal drops, 0.05% ,0.1% (hydrochloride)
tablet, 8 mg (dihydrochloride)
tablet, 4 mg ( hydrogen maleate)
tablet, 15 mgcapsule, 75 mg
scored tablet, 1 mg (as hydrogen fumarate)
tablet, 5 mg (maleate)
48
Medicine Route of administration, dosageforms and strengths
Level ofUse
28.3.1. Antifungal preparations (topical)
Amphotericin
Nystatin
28.3.2 Other anti-inflammatory and anti-infective
Chlorohexidine
Hydrogen peroxide
Polyvidone - iodine
Sodium chloride + sodium bicarbonate
Thymol + glycerin
C
C
B
B
B
B
B
oral suspension, 100 mg/ml
oral suspension, 100 000 units/ml
mouth wash, 0.2% (digluconate)
mouth wash, 1.5%
mouth wash, 1%
mouth wash, 1.5% + 1%
mouth wash, 0.05% + 10%
49
A
Index
Atropine 2, 5, 25, 34, 41Azathioprine 4,15Azithromycin 8
BBarium sulfate 30BCG Vaccine 38Beclomethasone 45, 48Bendrofumethiazide 31Benzathine benzylpenicillin 7Benzhexol 19Benznidazole 14Benzoic acid + Salicylic Acid 28Benzoyl peroxide 29Benzyl benzoate 29Benzylpenicillin 8, 40Betahistine 48Betamethasone 29Biperiden 19Bisacodyl 33Bleomycin 15Bonefosph 18Bran 33Bretylium tosilate 22Bromazepam 44Bromocriptine 36Bumetanide 31Bupivacaine 1Buspirone 44Busulfan 15
CCabergoline (dopamine agonist) 37Calamine lotion 29Calcium chloride 45Calcium folinate 18Calcium gluconate 5, 26, 46Capecitabine 15Captopril 23, 25Carbamezapine 6, 43Carbimazole 36Carboplatin 15Carmustine 16Carvedilol 26CCNU 16Cefaclor 8Cefadroxil 8
Abacavir (ABC) 11Acetazolamide 41Acetyl salicylic acid 3,15, 25Acetylcystine 5,41Aciclovir 10, 11, 28, 40Adenosine 22Albendazole 6Alcuronium 39Allopurinol 4Alpha interferon 18Alphacalciferol (one alpha) 36Alteplase 25Aluminium diacetate 29Aluminium hydroxide +Magnesium hydroxid 32Amantadine 19Amidotrizoate 30Amiloride 31Aminophylline 44Amiodarone 22Amitriptyline 43 Amlodipine 21Amoxicillin 7Amoxicillin + clavulanic acid 7Amphotericin B 10, 12Amphotrocin 49Ampicillin 7Antazoline 41Anti – D immunoglobulin 38Anti – D immunoglobulin (human) 38Anti scorpion sera 38Anti-haemorrhoidal medicine(local anaesthetic+ astringent + anti-inflammatory medicine) 32Antitetanus immunoglobin (human) 38Anti-venom sera 38Apomorphine 19Arimidex 17Artemether 13Artemether + lumefantrine 13Artesunate 13Artesunate (AS)+ sulphadoxine pyrimethamine(SP) 13Ascorbic acid 46Asparaginase 15Atenolol 21, 22, 23, 26Atorvastatin 27Atovaquone + proguanil 14Atracurium 39
50
51
Dapsone 10, 30Daunorubicin 16Deferoxamine 5Delvairidine (DLV) 12Desmopressin 20, 37Dexamethasone 4, 17, 34Dexamethasone+ framycetin sulphate+ gra-micidin 47Dextran 40 20Dextran 70 20Diazepam 2, 6, 44Diazoxide 23 Didanosine (ddi) 11Diethylcarbamazine 7Diethyl-tolumide 14Digoxin 24, 25Digoxin specific antibodies fragments 5Diloxanide 12Diltiazem 21Dimercaprol 5Diphenoxylate hydrochloride + atropinesulfate 33Diphtheria – pertussis – tetanus vaccine 39Diphtheria antitoxin 38Diphtheria vaccine 39Dipyridamole 25Disopyramide 22Dithranol 29Dobutamine 25, 26Docetaxel 16Domperidone 32Dopamine 25Doxazosin 23Doxorubicin 16Doxycycline 9Droperidol 2Dydrogesterone 37
EEfavirenz (EFV or EFZ) 12Eflomithine 14Enalapril 23Enoximone 24Entacapone 19Ephedrine 25, 26, 48Ephedrine hydrochloridel+ naphazoline 48Epinephrine (adrenaline) 1, 4, 26, 41Epirubicine 16Ergocalciferol 46Ergometrine 42Ergotamine 15
Cefixime 8Cefpirome 8Ceftazidime 8Ceftriaxone 8Charcoal , activated 5Chloral hydrate 44Chlorambucil 16Chloramphenicol 8, 40, 47Chlordiazepoxide 44Chlorine-base compound 31Chlormethine 16Chlorohexidine 31, 49Chloroquine 4Chloroxylenol 31Chlorphenamine 4, 48Chlorpromazine 42Cholestyramine powder 34Chorionic gonadotrophin 36Ciclosporin 15Cimetidine 32Cinnarazine 24, 26, 48Ciprofibrate 27Ciprofloxacin 9Cisplatin 16Citalopram 43Clarithromycin 9Clemastine 48Clindamycin 9Clobetasol 29Clofazimine 10Clomepramine 43Clomifene 36Clomipramine 44Clonazepam 6, 44Clopidogrel 25Clotrimazole 47Cloxacillin 8Clozapine 42Coal tar 29Codeine 3, 18Colchicine 4Cromoglicic acid 45Cyclizine 15Cyclopentolate 41Cyclophosphamide 4, 16Cyproterone acetate 36Cytarabine 16
DDacarbazine 16Dactinomycin 16Danazol 37
52
Glucose with sodium chloride 46Glutaral 31Glyceryl trinitrate 21Glycopyrronium 2Gn Rh agonist 37Gn Rh antagonist 37Gold 4Goserelin 17Griseofulvin 1, 28
HHaemodialysis solution 42Haloperidol 42Halothane 1Heparin sodium 20Hepatitis B immunoglobulin (HBIG) 34Hepatitis B vaccine 39Homatropine 41Human albumin 20Human menopausal gonadotrophin 37Hydralazine 23Hydralazine + Reserpine 23Hydrochlorothiazide 23, 32Hydrocortisone 4, 17, 29, 33, 34Hydrocortisone + clioquinol 47Hydrogen peroxide 31, 49Hydroxocobalamin 20Hydroxyurea 16Hyoscine butyl bromide 34Hyoscine hydrobromide 2
IIbuprofen 3Idarubicine 16Idoxuridine 40Ifosfamide 16Imatinib mesylate 18Imipenem + cilastin 8Imipramine 43Immunoglobulin, human normal 38Indinavir (IDV) 12Indolol+clopamide 23, 26Indomethacin 3Influenza vaccine 39Insulin injection (soluble) 36Intermediate-acting insulin 36Intraperitoneal dialysis solution 42Iodine 31, 46Iohexol 36Iopamidol 36Iopanoic acid 30
Erythrobioten 37Erythromycin 9Esmolol 22Ethambutol 10Ethanol 31Ethanolamine oleate 34Ether, anaesthetic 1Ethinylestradiol 35Ethinylestradiol + Levonorgestrel 35Ethinylestradiol + Norethisterone 35Ethinylestradiol + Progesterone 35Ethosuximide 6Etomidate 1Etoposide 16
FFactor IX Complex (coagulation factor II,VII, IX, X ) concentrate 21Factor VIIa (recombinant) 21Factor VIII concentrate 21Factor VIII recombinant 21Fentanyl 2, 18Ferrous salt 19Ferrous salt + folic acid 19Fibrous preparations 33Filgastrim 18Flecainide acetate 22 Fluconazole 10Flucytocine 11Fludrocortisone 34Flumazenil 3Flumetazone pivalate+ clioquinol 47Fluorescein 30Fluoxetine 43Flupenthixol 42Fluphenazine 42Flurouracil 16, 29Flutamide 17Fluvastatin 27Fluvoxamine 43Folic acid 20Fosfosterol 17Furosemide 31Fusidic acid 28
GGadolimium-DTPA 30Gas gangrene antitoxin 38Gentamicin 9, 40, 47Glibenclamide 36Glucose 46
53
Melphalan 17meningococcal vaccine 39Mercaptopurine 17Mesna 18Metaraminol 25, 27Metformin 36Methionine 5Methotrexate 4, 17Methoxsalen 30Methyl phenidate 44Methyldopa 23Methylrosanilinium Chloride (Gentianviolet) 28Methylthioninium chloride (methylene blue) 5Metoclopramide 2, 32Metolazone 32Metoprolol 26Metronidazole 9, 12Mexiletine 22Mianserin 43Miconazole 28Midazolam 2Milrinone 24Minoxidil 23Misoprostol (synthetic prostaglandin E1 ana-logue) 37Mitomycin 18Mitoxantrone 18Morphine 2, 3 , 19, 27Mumps vaccine 39
NNalidixic acid 9Naloxone 5Naproxen 3Nelfinavir (NFV) 12Neomycin + Hydrocortisone 48Neomycin+BacitracinB 28Neostigmine 40Nevirapine (NVP) 12Niclosamide 7Nicorandil 24, 26Nicotinamide 47Nifedipine 21, 23 , 42Nifurtimox 14Nitrazepam 44Nitrofurantoin 9Nitrous oxide 1Noradrenaline 26, 27Norethisterone 35, 36Norethisterone enantate 35Nystatin 11, 28, 49
Iopinavir + ritonavir (LPV/r) 12Iopromide 30Iotrolan 31Ipecacuanha 5Ipratropium bromide 45Iron dextran 20Iron sorbitol 20Isoflurane 1Isoniazid 10Isoniazid + Ethambutol 10Isoprenaline 22Isosorbide dinitrate 21Isosorbide mononitrate 21Ivermectin 7
KKetamine 1Ketoconazole 11, 28Ketotifen 45
LLabetalol 26, 27Lactic acid 29Lactulose 33Lamivudine 11, 34Lamivudine (3TC) 11Lamotrigine 6Levamisole 12, 22Levodopa + carbidopa 19Levonorgestrel 35Levothyroxine 36Lidocaine 1, 22Lisinopril 23Lithium carbonate 44Lopramide 36Lorazepam 44Losartan potassium 23
MMagnesium sulfate 33Malathion 30Mannitol 32Measles – mumps – rubella vaccine 39Measles vaccine (live attenuated) 39Mebendazole 7Mebeverine 34Medroxy- progesterone (depot) 17Medroxyprogesterone acetate 35, 36Mefloquine 14Megesterole 18Melarsoprol 14
54
Melphalan 17meningococcal vaccine 39Mercaptopurine 17Mesna 18Metaraminol 25, 27Metformin 36Methionine 5Methotrexate 4, 17Methoxsalen 30Methyl phenidate 44Methyldopa 23Methylrosanilinium Chloride (Gentianviolet) 28Methylthioninium chloride (methylene blue) 5Metoclopramide 2, 32Metolazone 32Metoprolol 26Metronidazole 9, 12Mexiletine 22Mianserin 43Miconazole 28Midazolam 2Milrinone 24Minoxidil 23Misoprostol (synthetic prostaglandin E1 ana-logue) 37Mitomycin 18Mitoxantrone 18Morphine 2, 3 , 19, 27Mumps vaccine 39
NNalidixic acid 9Naloxone 5Naproxen 3Nelfinavir (NFV) 12Neomycin + Hydrocortisone 48Neomycin+BacitracinB 28Neostigmine 40Nevirapine (NVP) 12Niclosamide 7Nicorandil 24, 26Nicotinamide 47Nifedipine 21, 23 , 42Nifurtimox 14Nitrazepam 44Nitrofurantoin 9Nitrous oxide 1Noradrenaline 26, 27Norethisterone 35, 36Norethisterone enantate 35Nystatin 11, 28, 49
Iopinavir + ritonavir (LPV/r) 12Iopromide 30Iotrolan 31Ipecacuanha 5Ipratropium bromide 45Iron dextran 20Iron sorbitol 20Isoflurane 1Isoniazid 10Isoniazid + Ethambutol 10Isoprenaline 22Isosorbide dinitrate 21Isosorbide mononitrate 21Ivermectin 7
KKetamine 1Ketoconazole 11, 28Ketotifen 45
LLabetalol 26, 27Lactic acid 29Lactulose 33Lamivudine 11, 34Lamivudine (3TC) 11Lamotrigine 6Levamisole 12, 22Levodopa + carbidopa 19Levonorgestrel 35Levothyroxine 36Lidocaine 1, 22Lisinopril 23Lithium carbonate 44Lopramide 36Lorazepam 44Losartan potassium 23
MMagnesium sulfate 33Malathion 30Mannitol 32Measles – mumps – rubella vaccine 39Measles vaccine (live attenuated) 39Mebendazole 7Mebeverine 34Medroxy- progesterone (depot) 17Medroxyprogesterone acetate 35, 36Mefloquine 14Megesterole 18Melarsoprol 14
55
Prazosin 24Prednisolone 4, 18, 33, 34, 40Probenecid 3Procainamide 22Procaine penicillin 8Procarbazine 17Prochlorperazine 48Procyclidine 19Promethazine 2, 32Propafenon 22Propofol 1Propranolol 15, 22, 24, 26Propyliodone 31Propylthiouracil 36Prostaglandin E2 37Protamine sulphate 20Purified FSH/ human (meopausal urine) 37Pyrantel 7Pyrazinamide 10Pyridostigmine 40Pyridoxine 47Pyrimethamine 14
QQuinidine 23Quinine 13
RRabies immunoglobulin 38Rabies vaccine 39Ranitidine 32Recombinant FSH (genetically engineered) 37Remifentanil 2Reserpine 24Retinol 47Riboflavin 47Rifampicin 10Rifampicin + Isoniazid 10Risperidone 43Ritonavir (RTV) 12Ropinirol 19Ropivicaine 2Rose bangal 30Rubella vaccine 39
SSalbutamol 42, 45Salicylic acid 29Salmetrol 45Selegiline 19Selenium sulfide 28
Nystatin+ neomycin+ gramicidin+ triam-cinolone acetonide 48
OOlanzapine 43Omeprazole 32Ondanosterone 2, 19Oral rehydration salt 33, 45Oxpentoifyllin 24, 26Oxygen 1Oxytocin 42
PPaclitaxel 17Pancuronium 40Paracetamol 3, 15Paroxetine 43Penicillamine 4, 5Pentamidine 13, 14Perindopril 24Permethrin 30Pertussis vaccine 39Pethidine 2, 4, 27Phenelzine 43 Phenindione 20Phenobarbital 6Phenoxymethylpenicillin 8Phentolamine mesilate 24, 25Phenylepherine 41Phenytoin 6Phytomenandione 20, 34Pilocarpine 41Pindolol 26Piroxicam 3pizotifen 15Plasma, human 21Podophyllum resin 29Poliomyelitis vaccine 39Polygeline 21Polymixin + Neomycin 28PolymyxinB sulfate + Neomycin sulfate +Hydrocortisone 38Polyvidone - iodine 49Potassium chloride 26, 45, 46Potassium ferric hexacyanoferrate(II).2H2O (Prussian blue) 5Potassium iodide 11, 36Potassium permanganate 28, 31 Povidone iodine 31Pravastatin 27Praziquantel 7
56
Triclabendazole 7Trifluoperazine 43Trimethoprim 10Tropicamide 30, 41Tuberculin, purified protein derivative (PPD) 38Tubocurarine 40Typhoid vaccine 39
UUrografin76% 31
VValproic acid 6, 44Valsartan 24Vancomycin 10Vasopressin 34, 37Vecuronium bromide 40Verapamil 22 , 23, 24Vigabatrine 6Vinblastine 17Vincristine 17Vindesine 17
WWarfarin 20Water for injection 46
XXamoterol 27Xylometazoline 48
YYellow fever vaccine 39
ZZalcitabin (ddc) 11Zidovudine (ZDV) 11Zidovudine+ lamivudine+ abacavir 12Zinc oxide 29Zinc sulfate 33Zolmitriptan 15Zolpidem tartrate 44Zuclopenthioxol 43
Senna 33Silver Sulfadiazine 28Simvastatin 27Sodium calcium edetate 5Sodium chloride 46Sodium chloride + sodium bicarbonate 49sodium cromoglicate 41Sodium fluoride 47Sodium hydrogen carbonate 26, 46Sodium lactate compound solution 46Sodium nitrite 5Sodium nitroprusside 24Sodium stibogluconate 13Sodium thiosulfate 5, 28Sotalol 27Spectinomycin 9Spironolactone 32Squinavir (SQV) 12Stavudine (d4T) 11Streptokinase 25Streptomycin 10Sulfacetamide 40Sulfamethoxazole + Trimethoprim 9, 14Sulfasalazine 4, 33Sulfinpyrazone 3Sumatriptan 15Suramin sodium 14Suxamethonium 40
TTamoxifen 18, 37Tenoxicam 3Terpinafine 28Testosterone 35Tetanus vaccine 39Tetracaine 41Tetracosactrin (ACTH analogue) 35Tetracycline 29, 40Theophylline 45Thiamine 47Thioguanine 17Thiopental 1Thiotepa 17Thymol + glycerin 49Ticlopidine 25Timolol 41Tirofiban 25Tobramycin 10Tocainide 23Topiramate 6Tramadol 19Tranexamic acid 38