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National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
1
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
2
SOUVENIR
National Seminar
On
“ POTENTIAL OF TRIBAL MEDICINE TO TREAT LIFE THREATENING DISEASES”
1ST November 2017
(Wednesday)
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
3
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
4
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
5
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
6
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
7
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
8
Organizing Committee
Mrs. Alka Dubey
Patron
Mr. Amresh Dubey
Patron
Convener
Dr. P. K. Dubey
Director
Swami Vivekanand Group of Institutions
Organizing Secretary
Mr. Satyaendra K. Shrivastava
Dean (Academics & Administration)
Swami Vivekanand College of Pharmacy
Coordinators
Dr. (Mrs.) Shikha Agrawal
Vice-Principal
Swami Vivekanand College of Pharmacy
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
9
Chairpersons of the committee
Registration
Committee
Dr. Priya Jain, Mrs. Steffy Mary Chandy,
Mrs. Pooja Pancholi, Mrs. Jyoti Jayaswal,
Mr. Praveen Sharma
Technical & Scientific
Committee
Mr. Dishant Gupta, Mrs. Archana Tiwari,
Mrs. Darshana Sharma, Mrs. Priya Jain, Mr.
Dilip Prajapati
Inauguration
Committee
Ms. Pooja Tiwari, Mrs. Priyanka Pandey,
Mrs. Khushboo Naik, Ms. Ankita Mane
Hospitality and
Transportation
Committee
Mr. Rupesh Pandey, Mr. Satyendra Yadav,
Mr. Sachin Okhade, Mr. Poonam S. Rajput
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
10
Editorial Board
Dr. P. K. Dubey Director
Dr. (Mrs.) Shikha Agrawal Vice-Principal
Mr. Satyendra K. Shrivastava Dean (Acad. & Admin.)
Dr. Priya Jain HOD (Ph. Chemistry)
Mr. Dishant Gupta HOD (Pharmacognosy)
Mr. Rupesh Pandey HOD (Pharmacology)
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
11
Programme schedule
On 01/11/2017
Time Schedule Programmed Details
Concurrent Sessions
09:00am-10:00am Registration & Breakfast
10:00am-11:00am Inauguration
11:00am-12:00pm Plenary Lecture I
12:00pm- 01:00pm Scientific Session
Lunch
02:00pm-03:00pm Scientific Session
03:00pm-04:00pm Valedictory Function
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
12
Abstract index
ABSTRACT NO.
TITLE NAME OF
PRESENTING
AUTHOR
PAGE NO.
PH/2017/01 Physicochemical Investigation of Vidanga
Berries
Sweta.V.Kulkarni 15
PH/2017/02 A Review on Recent Microbial Diseases:
Information on a Fatal Battle
Danish Pariyani 16
PH/2017/03 Synthesis and Evaluation of azetidin
derivatives as antimicrobial activity
M.C. Sharma 17
PH/2017/04 Traditional Phytotherapy among tribal and
local villages of Madhya Pradesh, India used
in the treatment of Gynecological Disorders
Shweta Shriwas 18
PH/2017/05 Application of liquisolid technique to enhance
solubility and dissolution profile of poorly
water soluble drugs
Madhavi Kasturi 19
PH/2017/06 Polymeric Microparticles containing herbal
plant extracts for managemet of diabetes
Neelima Salvi 20
PH/2017/07 Theraputic Profile of Mucunapruriense linn
Priyanka Singh 21
PH/2017/08 WHO Guidelines for Herbals
Deepanshi
Saklecha
22
PH/2017/09
Study of effect of Curcuma Zeodaria
roscoe. on oxidative-stress animal model
Elangovan
Manivannan
23
PH/2017/10 Herbal Hand sanitizer: Need for today
Virendra S
Rathore
24
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
13
PH/2017/11 Quality Control Parameters For Herbal
Drugs and Formulations
Twinkle Copuhan 25
PH/2017/12 Virtual Screening of Phyto-constituents as
anticancer agents
Nidhi Gupta 26
PH/2017/13 Tribal medicines used in treatment of
psoriasis
Gaurav patidar 27
PH/2017/14 A Review On Ethnomedicine Of Bhil Tribe
Of Jhabua District
Ayush Soni 28
PH/2017/15 A Review on Medicinal Plants used by the
Tribal People of Satna District, M.P.
Kundan Patidar 29
PH/2017/16 Traditional tribal medicines Aloe-vera used
as a anticancer drug
Manoj Gour 30
PH/2017/17 Tribal medicines in mosquito borne diseases
Nafia Rahman 31
PH/2017/18 Hypoxis in the treatment of hiv/aids
Harshita Sharma 32
PH/2017/19 A review on Swine Flu treatment by tribal
medicines using Tinospora Cordifolia
Akshat S Baghel 33
PH/2017/20 A Review On Tribal Medicine The Untapped
Treasure
Varsha Gadekar 34
PH/2017/21 A Review on Potential and Traditional Use
of Dioscorea Species (A Wild Edible Tuber)
by the Local People of Similipal Biosphere
Reserve, India
Chetna Mandloi 35
PH/2017/22 Tribal medicine Practices in North East
India
Deepak paudel 36
PH/2017/23
Linum usitatissimum used in Tribal
medicine
Khushali Pinge 37
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
14
PH/2017/24 Tribal medicine to treat Schizophrenia
Vrishti Thakur 38
PH/2017/25 Treatment of musculoskeletal diseases by
bonesetter shrub
Harsh Pendharkar 39
PH/2017/26 Tribal medicine to treat hepatitis B
Priya Gawla 40
PH/2017/27 Drumstick tree used as tribal medicine
Nikhil Gupta 41
PH/2017/28 Investigation of analgesic activity of
polyherbal preparation (Topical Gel)
containing herbal extract
Suman Gehlot 42
PH/2017/29 Formulation and Evaluation of herbal oil for
the treatment of arthritis
Sumeet Dwivedi 43
PH/2017/30 Pharmacognostical, Physicochemical and
Chromatographic Evaluation of Polyherbal
Formulation: Navasaya Churna
Nirmal Dongre 44
PH/2017/31 Formulation and evaluation of new nasal
drop using Essential Oil of Black Mustard
(Brassica nigra) for the Management of
Bacterial Rhinosinusitis
Harshit Sharma 45
PH/2017/32 Evaluation of Anti-diabetic activity of
Poly Herbal Antidiabetic Tablet Glucomap
Satyaendra K.
Shrivastava
46
PH/2017/33 Tribal medicine’- Antidote to snake venom
Zainab
Pandhanawala
47
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
15
Physicochemical Investigation of Vidanga Berries
Sweta V. Kulkarni*, Arun K. Gupta and Raju Choukse
School of Pharmacy, Dr.A.P.J.Abdul Kalam University, Indore, M.P
Abstract
Herbal medicines are being used as a effective source for treatment of
many diseases since ancient times. Embelin, is an active phytoconstituent
obtained from fruits of Embelia tsjeriam cottam, commonly known as
Vidanga. Vidanga consists of phytoconstituents which is used o cure
various severe diseases. Thus there is a need to justify the Quality of the
herbal drugs which are highly used nowadays. Standardization methods
hence act as an tests performed to ensure the safety of health. Also the
phytochemical investigation is performed to make the use of important
chemical constituents to its fullest. In this work we have performed
various evaluation tests as per Ayurvedic Pharmacopia which were found
to be within the limits. An effort was made further to optimize the best
extraction solvent. UV spectroscopic scanning was done from 200-400nm
of which λmax was found to be 291nm with a good peak shape and height
for chloroform. HPTLC studies revealed a better peak height for
Toulene:ethyl acetate and better separation of constitutents at
chloroform:methanol for chloroform solvent. Thus Chloroform was found
to the best solvent for extraction of vidanga berries.
Keywords: Vidanga, Embelia tsjeriam cottam, Phytochemical,
Standardization
*Corresponding Author Sweta V. Kulkarni
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
16
A Review on Recent Microbial Diseases: Information on a Fatal Battle
Danish Pariyani*, Vaibhav Sharma, Mili Satle, Jacky Dumbwani,
Sanjay Jain
Indore Institute of Pharmacy, Rau-Pithampur Road, Opp. IIM, Rau,
Indore-453331
Abstract
The whole world is facing a dangerous problem originated through variety
of microorganism. Infections can caused by microorganisms — such as
bacteria, viruses, fungi or parasites. Infectious disease is a significant
burden on the public health and economic stabilities of society all over the
world. It has become the leading cause of death and disability and
presented a challenge to health sector and human progress over some
decades. Over the last two, three decades many of the infectious disease
are identified like Hepatitis C, West Nile Virus, SARS, Chikungunya, Swine
Flu, MERS, Ebola, and Zika. Most of the diseases are zoonotic and there
origin has been due to environmental, socioeconomic factors. This review
presents the overview of the diseases, microorganism, drug and its
availability in the local area. Recently people are suffering from a panic
disease called chikungunya due lack of information patient are increasing
and are not getting proper treatment. This review also includes the
location of health centers and availability of drug in the city.
Key Words: Infectious Diseases, Public Health, Death, Environment,
Drug Availability
*Corresponding Author : Danish Pariyani
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
17
Synthesis and Evaluation of azetidin derivatives as antimicrobial
activity
M.C. Sharma*
School of Pharmacy, Devi Ahilya University, Khandwa Road, Indore, MP
452 001, India
Abstract
Present communication deals with the synthesis of a novel series of
compounds embracing azetidin nucleus in their molecular architecture. The
compounds were synthesized in excellent yields and their structures were
corroborated on the basis of IR, NMR, Mass analyses data. Moreover, the
antimicrobial potential of synthesized compounds was tested against a
panel of fungi. It also emphasizes the domination of steric properties over
the volumetric properties for modeling the activity against specific type
of bacteria. All the synthesized compounds have been found to delineate
profound antimicrobial potency as compared to reference drug.
*Corresponding Author- M.C. Sharma
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
18
Traditional phytotherapy among tribal and local villages of Madhya
Pradesh, India used in the treatment of Gynecological Disorders
Sumeet Dwivedi, Shweta Shriwas* and Raghvendra Dubey
College of Pharmacy, Dr. APJ Abdul Kalam University, Indore, (M.P.) -
India
Abstract
Madhya Pradesh, a Central State of India is rich in natural heritage due to
tribal impact. The wide diversity of natural resources of the state along
with the tribal population focuses in the use of herbs for the treatment
of various disease and disorders. Gynecological disorders viz., menstrual
disorders, vaginitis, uterine bleeding, vaginal inflammation, itching etc. are
now-a-days very common disorder almost in every woman. The tribe of the
region uses traditional herbs for the treatment of these disorders.
Available allopathic medicines are costly, have side effects and also due to
social custom, tribes of the region use herbs for the treatment of
gynecological disorders. The present paper enumerates fifty herbs viz.,,
Achyranthes aspera, Tachyspermum ammi, Plumeria pudica, Cissus
quandragularis, Nigella sativa, Ipomea mauritiana, etc. which are commonly
used to treat gynecological disorders. The local name, dose, duration,
disease condition treatment along with method of preparation has been
presented in present investigation.
Key-Words: Herbal remedies, Madhya Pradesh, Gynecological Disorders
*Corresponding Author: Shweta Shriwas
[email protected], [email protected]
Mob.+91-9893478497
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
19
Application of liquisolid technique to enhance solubility and dissolution
profile of poorly water soluble drugs
Madhavi Kasturi*
Department of Pharmaceutics, Smriti Collge of Pharmaceutical Education,
Indore, M.P, India – 452010
Abstract
“Liquisolid Technique” also known as “Powder Solution Technology” is considered
as new, safe and economic technique aiming for solubility and dissolution
enhancement which further increases the bioavailability of poorly water-soluble
drugs. This technique is based on the admixture of liquid medication with
appropriate carrier and coating materials. Liquid medication includes drug loaded
solutions or suspensions in non-volatile hydrophilic solvents such as PEG 400, PEG
600, Tween 80 etc. The use of hydrophilic non-volatile solvents causes improved
wettability and ensures molecular dispersion of the drug in the formulation that
leads to enhanced solubility. On the other hand, liquid medications containing
drug loaded emulsions by using hydrophobic nonvolatile solvents (vegetable oils),
one can modify release (sustained release) of drugs by this technique. Liquid
medication is combined with a carrier material (Avicel PH 102) having good
absorption properties and coating material (Aerosil 200) having high adsorptive
properties to obtain nonadherent, free-flowing readily compressible powder. It
is further mixed with disintegrants to form immediate release compacts. Hence
both immediate and sustained release of drug can be achieved with the help of
liquisolid technique. The liquisolid powder system can be transformed to
conventional solid dosage forms by compressing into tablets or filled into
capsules. By using this technique, solubility and dissolution rate can be improved
for poorly water-soluble drugs. The postulated mechanism for improved
solubility is due to their significantly improved wetting properties a greater
drug surface area is exposed to the dissolution media, resulting in an increased
dissolution rate and bioavailability. This technique proved an efficient method
for formulating water-soluble as well water-insoluble drugs.
Keywords: Liquisolid technique, carrier material, coating material, solubility
*Corresponding Author: [email protected]
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
20
Polymeric Microparticles containing herbal plant extracts for
managemet of diabetes
Neelima Salvi* and Choudhary
School of Pharmacy, Devi Ahilya Vishwavidyalaya, Indore, M.P, India –
452001
Abstract
Diabetes cannot be cured completely. Incidence of diabetes mellitus
increasing day by day. Synthetic drugs which are used for the treatment
of diabetes have many side effects and frequency of dosing is more. To
overcome such problems novel carrier system has been chose. Herbal
extracts have been widely accepted as the potential medicines with less
side effects as compared to synthetic drug molecules. Biodegradable
polymers are having wide use for the preparation of vesicular system to
control the drug release pattern of drugs. “Polymeric microparticles”
considered as novel carrier technique to control the release of herbal
plant extracts from vesicular system. Extraction of crude drugs (Hovenia
dulcis) done with successive solvent extraction method by using different
solvents like Petroleum ether, ethyl acetate, chloroform, methanol, and
ethanol. In phytochemical screening we found different constituents of
the plant but Dihydromyricetin, a flavonoid isolated, which decreases
blood glucose level. Polymeric microparticles formulated with hot melt
method and emulsification method. After characterization the
microparticles which are made from hot melt method shows good results
of drug release and entrapment efficiency. In the current research work
micoparticles has been developed of chitosan employed to enhance the
drug release. Polymeric micopartcles were characterized and evaluated
for antidiabetic activity. Hovenia dulcis decrease the blood glucose level in
albino rats
*Corresponding Author: Neelima Salvi, [email protected]
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
21
Theraputic Profile of Mucuna pruriense Linn.
Priyanka Singh*, Yukta Karam Chandani, Nirmal Dongre and Sanjay
Jain
Indore Institute of Pharmacy, Indore.
Abstract
Mucuna pruriense (Valvet bean) is amazing herbal drug, It is tropical
legume native of Africa and tropical Asia, Belongs to family Fabaceae.
Mucuna pruriense is an established herbal drug used for the management
of male infertility, nervous disorders, and also as an aphrodisiac. It has
been shown that its seeds are potentially of substantial medicinal
importance. The ancient Indian medical system, Ayurveda, traditionally
used M. pruriens, even to treat such things as Parkinson's disease. M.
pruriens has been shown to have anti-parkinson and neuroprotective
effects, which may be related to its anti-oxidant activity. It also shows
antidibetic activity. Mucuna pruriens var. utilis, an underutilized tropical
legume has a nutritional quality comparable to soya beans and other
conventional legumes as it contains similar proportions of protein, lipid,
minerals, and other nutrients.In this review the medicinal properties of M.
pruriens are summarized.
Keywords: Mucuna pruriens, Phytochemicals, Antioxidant, Parkinson's
disease, Skin, Diabetes
*Corresponding Author: Priyanka Singh
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
22
WHO Guidelines for Herbals
Deepanshi Saklecha* Anjali Soni, Divya Goswami,Nirmal Dongre and
Sanjay Jain
Indore Institute of Pharmacy, Indore.
Abstract
Herbal medicines are the oldest form of healthcare known to humanity
and has been used in all cultures throughout history. Quality control and
standardization Reduce adulterations with substandard drugs, improper
authentication, scientific validation of the therapeutic claims, Identity,
purity, efficacy and safety Customer satisfaction and confidence.
Mistaken use of wrong species incorrect dosing, Poor quality products,
Toxicity Interactions with other medicines.Misconception that all herbs
are safe Misuse of herbal drugs Safety in quality management. To
overcome these problems World Health Organization (WHO) issues
Guidelines for herbals A set of guideline for the assessment of herbal
remedies has been published by WHO. These guidelines specify criteria to
be used in evaluating commercial crude drugs intended for use (WHO
Traditional Medicine Strategy 2002-2005). WHO guidelines on safety
monitoring of herbal medicines in pharmacovigilance systems (2004). By
following the guidelines of WHO, we can ensure the quality and Safety of
herbals.In this Review we summarize the guidelines provided by WHO.
Keywords: - WHO, Traditional Medicine
*Corresponding Author: Deepanshi Saklecha
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
23
Study of effect of Curcuma Zeodaria roscoe. on oxidative-stress
animal model
Elangovan Manivannan*, Rajesh Sharma, Narendra Shinde
School of Pharmacy, Devi Ahilya Vishwavidyalaya, Ring Road, Indore-
452001 (M.P.), India.
Abstract
Reactive oxygen species (ROS) have been implicated in many human
diseases such as inflammation, arthritis, cardiovascular aliments, cancer,
diabetes, Alzheimer's disease, and various forms of neurodegenerative
disorders. Curcuma Zeodaria Roscoe., a plant species has been valued in
Indian system of traditional medicine for treatment of wide range of
diseases and reported to have its therapeutic benefit through its
antioxidant property. Thus, the present study was aimed to investigate
the antioxidant potential of rhizome extract of Curcuma Zeodaria Roscoe.
The methanol extract of rhizome was prepared and investigated using in
vitro assays, scavenging ability against 2,2'-diphenyl-2-picrylhydrazyl
(DPPH), and in vivo anti-oxidant potential by cold-immobilization induced
oxidative stress animal model. The maximum antioxidant activities were
observed with minimum concentration, >100 µg/ml of methanol extract of
Curcuma Zeodaria by DPPH based free radical scavenging assay. In the
cold-immobilization oxidative stress study, it was observed that the
Curcuma Zeodaria extract treatment decreased the increased level of
lipid peroxide in liver and brain tissues very significantly. The
histopathological examination of liver and brain tissues showed a
significant protective effect of Curcuma Zeodaria extract against strong
free-radical damage.
Keywords: Curcuma Zeodaria Roscoe; Oxidative-stress; Reactive oxygen
species; Antioxidant
*Corresponding Author: Elangovan Manivannan
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
24
Herbal Hand sanitizer: Need for today
Virendra Singh Rathore*, Shubham Sharma, Nayany Sharma and
Sanjay Jain
Indore Institute of Pharmacy
Abstract
Hands are the most common mode of transmission of the microorganisms
or other infections so hand hygiene plays important role in preventing the
acquired infections. Use of hand sanitizers can help in prevention, control
and reduction of the healthcare acquired infections. Hand sanitizers can
stop transmission of microorganisms from one hand to different parts of
the body and also to other people. Nosocomial infections are increasing
alarmingly and have emerged as a critical issue in hospital care outcome.
Hand sanitization is the preeminent aid in preventing infections caused by
different opportunistic microorganisms and to get this, the use of hand
sanitizer becomes must in recent circumstances. Hand sanitizer avoids
adverse effects like itching, irritation, dermatitis etc. Plants are the rich
source of primary and secondary plant metabolites having particular
therapeutic activities. If the microorganisms reach in to the blood stream
and end up in many different body sites causes wound infections,
abscesses, osteomyelitis, endocarditis and pneumonia.
Keywords: Hand sanitization, Noscomial infections
*Corresponding Author: Virendra Singh Rathore
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
25
Quality Control Parameters For Herbal Drugs and Formulations
Twinkle Copuhan*, Sneha Sable, Shanu Muchhala, Nirmal Dongre and
Sanjay Jain
Indore Institute of Pharmacy, Indore.
Abstract
The use of herbal medicine is increasing in developed countries due to
increasing awareness and general acceptability of herbal drugs in today’s
medical practice. Although, most of these applications are unorthodox, it
is however a known fact that over 80% of the world population depends on
herbal medicines and product for healthy living. This rise in the use of
herbal product has also given rise to various forms of abuse and
adulteration of the products leading to consumers’ and manufacturers’
disappointment and in some instances fatal consequences. The challenge is
innumerable and enormous, making the global herbal market unsafe. This
review seeks to enlighten stakeholders in herbal medicine on the need to
establish quality parameters for collection, handling, processing and
production of herbal medicine as well as employ such parameters in
ensuring the safety of the global herbal market. The processes of good
quality assurance and standardization of herbal medicines and products
were also discussed.
Key words: Herbal medicine, standardization, quality control.
*Corresponding Author: Twinkle Copuhan
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
26
Virtual Screening of Phyto-constituents as anticancer agents
Nidhi Gupta*, Love Kumar Soni
School of Pharmacy, Devi Ahilya University, Khandwa Road ,
Indore 452001(M.P.)
Abstract
Protein tyrosine kinase (PTKs) are key enzymes in cell signalling pathway
and play crucial role in a wide variety of diseases including cancer. PTKs
are the enzymes, which catalyzes the transfer of the γ phosphate of ATP
to tyrosine residues on protein substrates. The Phosphorylation of
tyrosine residue is one of the key covalent modifications which modulates
the enzymatic activity and creates the binding sites for the recruitment
of downstream signalling proteins. To overcome the adverse effects of
synthetic compounds curcumin and resveratrol is taken as a herbal
medicine for treating life threatening disease cancer. In order to gain
most potent and lead compound as a tyrosine kinase inhibitors Docking
studies of both compounds have been performed on Pdb:1M17 by using
Molegro Virtual Docker(MVD) 6.0 software. Common amino –acid bindings
are observed in both compounds which show similar interaction as
mentioned in the pdb data base. Docking study revealed that Steric and
H-bonding interactions play significant role against receptor tyrosine
kinase enzyme for their anticancer activity. Docking score and similar
amino-acid binding interactions provide us an idea for designing of new
lead and more potent analogues.
Key-words : Protein Tyrosine kinase, Curcumin, Resveratrol, Docking,
Anticancer activity.
*Corresponding Author: Nidhi Gupta
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
27
Tribal medicines used in treatment of psoriasis
Gaurav patidar*, Aditi Verma, Aditya Jain, Hemant Khambete, Sanjay
Jain
Indore Institute of Pharmacy, Indore
Abstract
Psoriasis is a skin condition that results in patches of skin with silvery
scales, and red and flaky areas that can be itchy, sore, or sometimes
painful. The most common areas affected are the scalp, elbows, knees, and
lower back, although any skin surface may be involved. It can also occur in
the nails and body folds. Psoriasis is not contagious and cannot be passed
from person to person, but it can occur in members of the same family.
Psoriasis starts as small red bumps, which enlarge and become scaly. The
skin appears thick, but bleeds easily if the scales are picked or rubbed
off. The exact cause of psoriasis is unknown, but it is believed that a
combination of factors contributes to the development of the condition.
An abnormality in the immune system causes inflammation in the skin,
triggering new skin cells to develop too quickly.
There are many treatments for psoriasis. Some treatments slow the
production of new skin cells, while others relieve itching and dry skin.
There are various tribal herbal drugs used for treatment of psoriasis that
mainly includes Aloe Vera, Apple Cider Vinegar, Capsaicin, Dead Sea Salts,
Oats, Tea tree oil, Turmeric and Mahonia Aquifolium (Oregon grape). The
present review focus on various herbal treatment approaches for
psoriasis.
Key Words: Psoriasis, Herbal, Aloe, Capsaicin, Skin disease
*Corresponding Author: Gaurav Patidar
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
28
A Review On Ethnomedicine Of Bhil Tribe Of Jhabua District
Ayush Soni*, Kundan Patidar, Harshit Kurmi, Deepak Saad
Swami Vivekanand College Of Pharmacy, Indore (M.P)
Abstract
The Bhils are inhabitants of Dhar, Jhabua, Khargone and Ratlam distrcits
of Madhya Pradesh. A large number of Bhils live in the neighbouring
States of Maharashtra, Gujarat and Rajasthan. They constitute the third
largest tribe of India; the first two being Gonds and Santhals. They
utilize a large number of plant species occurring wild in the district as
herbal remedies in various diseases and ailments. An ethno-medico-
botanical survey was conducted in the tribal blocks. Viz. Kathiware,
Alirajpur and Sodhwa blocks of Jhabua district, M. P. The authors have
gathered first-hand information on seventy – five plant species and their
mode of therapeutic uses from the tribal medicine men ‘Badwa’ and other
experienced tribals. The present study has brought of light some
interesting data on potential medicinal plants which will be screened for
determining their therapeutic and pharmacodynamic properties.
*Corresponding Author: Ayush Soni, [email protected]
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
29
A Review on Medicinal Plants used by the Tribal People of Satna
District, M.P.
Kundan Patidar*, Ayush Soni, Harshit Kurmi, Dishant Gupta
Swami Vivekananda College Of Pharmacy, Indore, (M.P.)
Abstract
Gastrointestinal Aliments Are Very Common Among The People Of Our
Country And Tribals Believe That It Is A Root Cause For The Occurrence
Of Several Other Diseases. Modern Synthetic Medicine Has So Far Not
Produced Any Effective Curative Drug. It Only Gives Temporary Relief.
However,Traditional Herbal Medicines Have A Better Remedy For The
Diseases Of Digestive System. In The Present Paper Herbal Preparations
Used For Gastrointestinal Disorders By Tribal And Rural People Of Satna
District, Madhya Pradesh Has Been Discussed. An Effort Is Also Made To
Correlate Modern Uses And Activities Of Plant, With The Plants Used By
Tribals And Rural People For The Curative Purpose Of Gastrointestinal
Disorders.There Are Six Tribe Types Are Dominatingly Exist In The
Satna District.India Has Vast Resources Of Medicinal Plants. The Use Of
The Plants As Medicine Is Nothing New But According To An Estimate
There Are More Than 25000 Effective Herbal Formulations Exist In The
Country. In The Study Area Of Majhgawan Region Only Three Tribes Are
Dominant, Namely Kol, Gond And Mawasi.
Keywords: Tribes. Ethno-medicinal Plants. Gastrointestinal Disorders.
Majhgawan. Satna. Madhya Pradesh
*Corresponding Author: Kundan Patidar, [email protected]
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
30
Traditional tribal medicines Aloe-vera used as a anticancer drug
Manoj Gour*,Steffy Mary Chandy, Akshat Singh Baghel,
Nikhil Gupta, Khushali Pinge, Avani Swami
Swami Vivekananda College of Pharmacy, Indore
Abstract
Aloe Vera leaf gel enables the body to heal itself from cancer and also
from the damage caused by radio and chemotherapy that destroys healthy
immune cells crucial for the recovery. Aloe Vera acts as radiation
protectors and inhibits testicular damage from gamma radiation and
reduces cancer. Aloe Vera leaf contains anthraquinones, saccharides,
vitamin E and C, zinc, enzymes, acetyl salicyclic and others. Acemannan is
the major carbohydrate fraction obtained from Aloe Vera leaf. This
fraction promotes wound healing, has antiviral, anticancer and immune
stimulation effect. Compounds extracted from Aloe Vera have been used
as an immunostimulant that aids in fighting cancer. Aloe Vera emodin, an
anthraquinone, has the ability to suppress or inhibit the growth of
malignant cancer cells making it to have antineoplastic properties.
Keywords: Immunostimulant, anthraquinone, chemotherapy
*Corresponding Author: Manoj Gour
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
31
Tribal medicines in mosquito borne diseases
Nafia Rahman*, Aman Mourya, Bhavesh Mathankar, Steffy Mary
Chandy
Swami Vivekananda College Of Pharmacy, Indore
Abstract
Malaria and other mosquito vector borne diseases prevalent globally .In
India, people often have no or limited facilities at their places. Further
due to lack of proper knowledge, local village people have to rely on
traditional medicines for treatment of the disease. Ethnomedicinal plants
and animals commonly used by tribal people to cure malaria and other
fever, in the Meikal hill region of Amarkantak were surveyed and
documented. The study revealed that plants like Van Adarak-zingiber
zerumbet (L) Zingiberceae. Andrographispaniculata Acanthaceae, Vanjira-
Asteraceae, Crinum asiaticum, Centratherum . Traditional tribal medicines
that are used by the tribal peoples for the treatment of malaria fever and
other documentation of tribal medicines for the generation of new
medicine that may be possible to control new communicable &vector borne
diseases like malaria, swine flu, bird flu, etc.
Keywords:Malaria, Ethnomedicinal plants, Zingiberceae, Asanthaceae,
Vanjira-Asteraceae, Crinum asiaticum, bird flu, swine flu.
*Corresponding Author: Nafia Rahman
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
32
Hypoxis in the treatment of HIV/AIDS
Harshita Sharma*
Swami Vivekanand College of Pharmacy, Indore
Abstract
Herbal medicines are often used as primary treatment for HIV/AIDS and
for HIV-related problems. In general, traditional medicines are not well
researched, and are poorly regulated. Two principal African herbal
compounds used for HIV/AIDS treatment in sub-Saharan Africa
include Hypoxishemerocallidea (common name: African potato),
and Sutherlandia. Hypoxis as an immunostimulantfor patients with
HIV/AIDS. A daily dose of 2,400 mg of raw plant is purported to be
therapeutically effective. There is some indirect evidence that sterols
and sterolins, which are found in the root of Hypoxis, have the potential
to enhance immunity.The plant also contains various sterols (β-sitosterol,
stigmasterol) and their glycosides (sterolins) such as β-sitosterol
glycoside and stanols such as sitostanol also called stigmastanol, which
have also been purported to have important biological activity.
Keywords:Immunostimulant, sterolins, Hypoxis.
*Corresponding Author: Harshita Sharma
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
33
A review on Swine Flu treatment by tribal medicines using Tinospora
cordifolia
Akshat Singh Baghel*, Archana Tiwari , Nikhil Gupta, Manoj Gour ,
Khushali Pinge
Swami Vivekanand College of pharmacy, Indore
Abstract
Tinospora cordifolia is also known as heart leaved moonseed , commonly
known a Giloy. It is divine in medicinal use, it actively fights with many life
threating diseases from the stanvard of the tinospora cordifolia chemical
tinosporaside that is 18-norcherodne diterpene O-glucoside, have the
property of Anti-pyretic which actively fights against the Swine flu n due
to this this is mostly agains it,by building up the immunity readily and
shoes action on antibiotics to fight activity. One more another chemical
Baberine plays Vital role agains Arrhythmia that is irregular Heartbeat
and hyperlipidemia. It also purify the blood so it also fight against the
diabetes and various types of cancer.It also do not have any negative side
effect . The bitter properties present in the drug show anti-periodic
(Preventing regular recurrence of the symptoms of a disease, as in
malaria) and antispasmodic properties which is again helpful in preventing
infectious diseases like dengue, swine flu, malaria etc.
Keywords: hyperlipidemia , Anti-pyretic , life threating diseases
*Corresponding Author: Akshat Singh Baghel
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
34
A Review On Tribal Medicine The Untapped Treasure
Varsha Gadekar*, Premlata Patel, Rashi Agrawal,Sakshi Laad
Swami Vivekanand Collage of Pharmacy, Indore
Abstract
In recent years, uncontrolled exploitation by Multinationals has resulted in the loss of
the rich biodiversity of India, which has an immense wealth of about 45,000 species of
wild plants of which 7500 species are used for medicinal purposes. The tribal people are
the real custodians of medicinal plants. Dr. Vedavathy (2002) has recently reported the
results of a study carried out between 1994-1998 in Andhra Pradesh. From the Chittoor
district alone they have documented more than a thousand therapies and 500 medicinal
plants. The predominant tribal populations in the district comprise
the yanadi, yerukala, nakkala and the irula tribes.The Herbal Folklore Research Center
(HFRC) with a small multi-disciplinary team comprising an ethno-botanist, a social
anthropologist, two trained taxonomists, an Ayurvedic doctor and four field assistants,
made enthno-botanical surveys during 1994-1998 in the Chittoor district, in Andhra
Pradesh. The surveys were carried out with a non-random purposive sample of the rural
population. 'Snowball and judgmental' selection methods were used to identify
community members who are knowledgeable in medicinal plant identification and usage.
Vedavathy noticed that there is a strong belief among the tribal people that the
efficacy of the therapy is lost if it is revealed to strangers, who have no faith in nature
and their medicine. Fever: If the ailment is followed by fever the first precaution is to
avoid intake of solid food. During the survey the team documented six types of
antipyretic agents such as the decoction of root tubers of (shatavari), Asparagus
racemosus Willd or Cyprus rotundus used by the Yanadi tribe. The Sugalis used the
garlic bulb (Allium sativum Linn), and dry ginger. And the Nakkala tribe used the
decoction of garlic mixed with Andrographis paniculata and Morinda tinctoria root.
Headache: For headache the tribals use either dry ginger or sandal wood paste as
topical application on the forehead and for pain in the scalp region they bandage either
leaves of Delonix elata Gamble or Vitex negundo Linn. For chronic cases they make a
paste of Achyranthes aspera Linn, earthworm and Ocimum basilicum Linn seeds mixed
with a pinch of camphor, which is applied on the head and forehead. If the headache is
followed by fever and eye infection the juice made by pounding ginger, garlic and onion
is given to drink .
Key words:-Uncontrolled exploitation by multinationals, Asparagus racemosus, Allium
sativum
*Corresponding Author: Varsha Gadekar , [email protected]
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
35
A Review on Potential and Traditional Use of Dioscorea Species (A
Wild Edible Tuber) by the Local People of Similipal Biosphere Reserve,
India
Chetna Mandloi*, Dharita Desai, Aarti Jaiswal, Neelam
Kushwah,Darshana Sharma
Swami Vivekanand College Of Pharmacy, Indore, (M.P.)
Abstract
A number of wild crops remain unexplored in this world and among them some
have excellent medicinal and nutritional properties. India is a harbour of
biodiversity in general and phytodiversity in particular. The plant diversity is
distributed from the Western Ghats to Eastern Ghats, along with the North-
Eastern region and from the Greater Himalayas to the plain of Ganga. Among
these distributed floral regions of the country, the Eastern Ghats are important
due to their rich floral diversity. The forests of Odisha form a major part of
Eastern Ghats in general and the Similipal Biosphere Reserve (SBR) in particular.
The SBR is inhabited by many local communities. The food and medicinal habits
of these communities are not fully explored even today. They are dependent on
the forests of SBR for their food and medicine. Among their collections from
forests, root and tuberous plants play a significant role. The local communities
of SBR use about 89 types of tuberous plants for various purposes. Dioscorea is
one such tuber, having maximum use among the local of SBR. However, less
documentation and no specific reports are available on the food and medicinal
values of the species available in this part of the World. Dioscorea species,
popularly known as Yam worldwide and as Ban Aalu in Odisha, India, is a prime
staple medicinal-food substitute for the majority of rural and local people of
the state of India. Of the 13 Dioscorea species available in SBR, 10 species are
known to be bitter in taste and unpalatable when taken raw. Since less
documentation is available on the Dioscorea species of SBR and their traditional
uses, the present study was focused on the ethnobotany, nutritional and
pharmacological values of these species along its nutraceutical importance.
*Corresponding Author: Chetna Mandloi , [email protected]
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
36
Tribal medicine Practices in North East India
Deepak Paudel*
Swami Vivekanand College Of Pharmacy, Indore, (M.P.)
Abstract
India is one of the biggest country in terms of diversity and northeast is
heart of its wildlife diversity. Northeast region of the India comprising
states of Arunachal Pradesh, Assam, Manipur,Meghalaya, Mizoram,
Nagaland, Sikkim and Tripura still follow the age old traditional healing
systemsbased on their tribal method & practices. People living the tribal
life style in these regions they live long & are healthier they are using
plant of these regions and thriving on medicinal aspects. Each state is
having its own dialect, plant and resources for meeting out the
requirement of community including health facilities they are important to
region due the terrain of the area. They all adaptherbs, animal parts,
mantras for keeping them healthy. During various studies it was observed
that thetraditional healers in this region belong to different categories
like herbalist, diviners and birth attendantsetc. Their method of
treatment, ethics and significance of traditional healing practices are
discussed inthis abstract. Now, scientific validation and recognition of
traditional healing medicines are urgentlyrequired for revitalizing this
loosing traditional knowledge.
Key words: Diviner, Herbalist, Livelihood, Traditional Healers, Tribes
*Corresponding Author: Deepak paudel
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
37
Linum usitatissimum (Flaxseed) used in Tribal medicine
Khushali Pinge*, Manoj Gour,Pooja Tiwari and Akshat Singh
Swami Vivekanand College of Pharmacy, Indore, (M.P.)
Abstract
The benefits of flaxseed make it a superfood you need to add to your anti-cancer
eating plan. Ongoing studies like the one at the University of Illinois show that these
sesame seed-sized kernels may prevent serious illness.Experts believe this is due to the
phytochemicals and phytoestrogens as well as the omega-3 fatty acids contained within.
These compounds working together provide a strong protective benefit to our bodies.
Health Benefits of Flaxseed. Cancer protection. Regular consumption of flaxseed may
protect the body from colon cancer, prostate cancer, and breast cancer. Omega-3 fatty
acids prevent cancerous cells from latching onto healthy cells. If cancerous tumors
attempt to form, the lignans contained in flaxseed stop the formation of new blood
supply (anti-angiogenesis) that feeds tumor growth. In other words, they starve the
tumor of their supply of oxygen and nutrients. If cancer cells can’t get these basic
requirements, they are unable to multiply and spread.Flaxseed is the richest dietary
source of lignans, a type of phytoestrogen. A phytoestrogen is a plant nutrient that is
somewhat similar to the female hormone estrogen. Due to this similarity, lignans may
have estrogenic and/or anti-estrogenic effects in the body. Lignans are the nutrients
that are at the center of the controversy regarding whether it is safe for women with
breast cancer to eat flaxseeds.Phytoestrogens are found in a variety of foods, including
soy, flaxseeds, other nuts and seeds, whole grains, and some vegetables and fruit. Most
of the research regarding flaxseed and breast cancer focuses on the lignans found in
flaxseeds, and their potential for weak estrogenic or anti-estrogenic effects in a
woman’s body.Lignans, which are the type of phytoestrogens in flaxseed, can change
estrogen metabolism. In postmenopausal women, lignans can cause the body to produce
less active forms of estrogen. This is believed to potentially reduce breast cancer risk.
There is evidence that adding ground flaxseeds into the diet decreases cell growth in
breast tissue as well. Again, this would be the type of change that would be expected to
decrease breast cancer risk.
Keywords:- kernels, lignans, phytoestrogen, consumption, metabolism, controversy,
latching.
*Corresponding Author: Khushali Pinge
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
38
Tribal medicine to treat Schizophrenia
Vrishti Thakur*, Ankita Tikariya, Aayushi Dhangar, Satyaendra
Shrivastava
Swami Vivekanand College Of Pharmacy Indore (M.P.) India
Abstract
Schizophrenia is a subtle disorder of brain development and plasticity; it
affects the most basic human processes of perception, emotion, and judgment.
In the traditional medical practitioners of rural and remote areas characterized
the schizophrenia as an insanity or a mental problem due to possession by ghosts
or evil spirits and they have used various plant species’ to treat such symptoms.
The aim of the present study was to conduct an ethnomedicinal plant survey and
documentation of the formulations of different plant parts used by the
traditional medical practitioners for the treatment of schizophrenia like
psychosis. It was observed that the traditional medical practitioners used a
total of 15 plant species to make 14 formulations. The plants were divided into
13 families, used for treatment of schizophrenia and accompanying symptoms
like hallucination, depression, oversleeping or insomnia, deterioration of personal
hygiene, forgetfulness, and fear due to evil spirits like genies or ghost. A search
of the relevant scientific literatures showed that a number of plants used by
the medicinal practitioners have been scientifically validated in their uses and
traditional medicinal knowledge has been a means towards the discovery of many
modern medicines. Moreover, the antipsychotic drug reserpine, isolated from
the dried root of Rauvolfia serpentina species, revolutionized the treatment of
schizophrenia. So it is very much possible that formulations of the practitioner,
when examined scientifically in their entireties, can form discovery of lead
compounds which can be used as safe and effective antipsychotic drug to treat
schizophrenia.
Keywords:- Schizophrenia, Ethnomedicinal, Traditional medical practitioner
*Corresponding Author : Vrishti Thakur
.
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
39
Treatment of musculoskeletal diseases by bonesetter shrub
Harsh Pendharkar* , Priya Jain
Swami Vivekanand College of Pharmacy, Indore, (M.P.)
Abstract
“Tribal medicine is a kind of traditional medicines, which are used by tribes in
the forest. It is still in the primitive form. A study about tribals medicine will be
incomplete without the background of traditional medicine. The term “traditional
medicine” refers to way of protecting and restoring health that existed before
the arrival of modern medicine.The Bonesetter (Cissus quadrangular) shrub
belongs to the family Vitaceae. The typical lquadrangular shape of the stem has
given this plant its species name. It is asucculent creeper found trailing over
bushes and fences. In many of the tribal belts in India the local people have
successfully used this plant to mend skeletal fractures,muscle injuries and
sprains.This plant is also used to treat Amenorrhea or absence of menstruation
and painful menstruation. In Amenorrhea, prepare ash of this plant by crushing
the stem andmixing it with pinch of salt. Then burn it over coal on a slow fire.
Take a pinch or two of this ash along with one teaspoon of clarified butter or
ghee.Administratorthis three times a day for 3-7 days. For injuries, muscular
pain and sprains, grind thewhole plant into a fine paste with equal quantities of
fresh turmeric rhizomes. Applya good amount on the affected parts.The plant of
Bonesetter(Cissus quadrangular) grows commonly in the hotter anddrier regions
of India, including the Deccan peninsula, extendingwest to the lowereastern
slopes of the western Ghats and south to Travencore. It is also widespread
inthe drier parts of Africa and Arabia.
It is researched that many local tribes of India and Africa used many herbs and
treeproduct directly or indirectly to treat their diseases and disorders.
Bonesetter(harjor) is one of them medicinal plant which is used by tribals of
these region.
*Corresponding Author : Harsh Pendharkar
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
40
Tribal medicine to treat hepatitis B
Priya Gawla*, Satyendra K Shrivastava, P.K. Dubey
Swami Vivekanand College of Pharmacy, Indore (M.P.)
Abstract
The term 'hepatitis' simply means inflammation of the liver. Hepatitis may
be caused by a variety of viruses or other infections, medications, or a
toxin such as alcohol. Hepatitis viruses that can cause injury to liver cells
in addition to hepatitis B include the hepatitis A and hepatitis C viruses.
The hepatitis B virus reproduces in liver cells, but the virus itself is not
the direct cause of damage to the liver. Rather, the presence of the virus
triggers an immune response from the body as the body tries to eliminate
the virus and recover from the infection. This immune response causes
inflammation and may seriously injure liver calls.
Hepatitis B is endemic in Southeast Asia, estimated to infect up to 20%
of the population. Licorice was an ingredient in many of the prescriptions
used in ancient times to treat hepatitis. The root is well-known for its
anti-inflammatory activity. Curcuma (yujin) refers to one of three major
species of curcuma used in Chinese medicine, the other two are turmeric
(huangjiang) and zedoaria (ezhu). It contains a complex essential oil that
regulates blood lipids and treats infectious hepatitis. Ligustrum refers to
the seed of Ligustrum lucidum. It is rich in oleanolic acid, a compound that
appears to be effective in treatment of liver diseases, acting mainly as a
liver-protective agent. Silymarin is a complex flavonoid from Silybum
marianum, its main action is to protect the liver from damage.
Keywords: Hepatitis, ligustrum, oleanolic acid.
*Corresponding Author: Priya Gawla
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
41
Drumstick tree used as tribal medicine
Nikhil Gupta*,Pooja Tiwari, Akshat Singh Baghel
Manoj Gour, Khushali Pinge, Avani Swami
Swami Vivekananda College of Pharmacy, Indore
Abstract
Drumstick tree is one of the most powerful health-enhancing. Drumstick
tree leaf is best known as an excellent source of nutrition and natural
energy booster. Traditionally drumstick tree has been used medicinally as
an anti-bacterial, anti-viral, anti-diabetes agent, and has been shown to
lower harmful blood fats and high blood pressure. Drumstick flower are
useful in intestinal worm. It balances pitta and kapha. The oil which is
prepared by drumstick tree is useful in skin diseases and diabetes. The
parts of drumstick tree are : drumstick’s root bark, stem bark, leaves,
fruits and seeds are used for therapeutic purposes.. Black variety of
drumstick tree is the most common. Its qualities are Deepana ( improves
digestion ), Kshara – Has alkaline properties Vidaahakrit – causes burning
sensation Sangrahi – Useful to check diarrhoea Hrudya Pittarakta
prakopana: Increases Pitta and vitiates blood Chakshushya – Improves
vision, Kaphavataghna–Decreases imbalanced Kapha and Vata Vidradhi –
Useful in abscess. It helps in quick wound healing of abscess, upon oral
intake and external application as paste. Shvayathu – It is a good anti
inflammatory herb. Visha – Anti toxic. Has detoxifying action. Pleeha –
Useful in spleen related diseases Gulma – Useful in abdominal bloating and
tumors , Ganda Vrana – Useful in lymphadenitis.
Keywords: Anti-bacterial, anti inflammatory , energy booster
*Corresponding Author: Nikhil Gupta
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
42
Investigation of analgesic activity of polyherbal preparation (Topical
Gel) containing herbal extract
Suman Gehlot1*, Sumeet Dwivedi1, Abhishek Dwivedi2 and S.N.Dwivedi4
1, College of Pharmacy, Dr. APJ Abdul Kalam University, Indore, (M.P.) -
India
2, Department of Pharmacy, RKDF University, Bhopal, (M.P.) - India
Abstract
Available synthetic analgesic drugs have several side effects viz.,
gastritis, gastric ulcer, kidney disorders and cardiac arrhythmias.
Therefore, the use herbs are an important and growing part of the pain-
control and new discoveries are made practically every year. Many of
these drugs commit the side effects like Morphine is responsible do work
against heavy sedation and may elevate mood in distressed patients as do
the antidepressants. Caffeine, release the histamine in more amounts, also
have stimulation. And the use of cannabis like a medicine remains a
debated issue. Analgesic herbs are the therapeutic herbs with analgesic
effect that are commonly known as pain relief herbs or simply the pain
herbs. Analgesic herbs are natural pain reliever that reduce or eliminate
pain. These pain relief herbs are available in the market in analgesic
topical forms like essential oil and analgesic cream- that can be directly
applied at the pain sites- as well as in form of capsules, tea and tinctures
for pain relief. The present paper deals with the formulation and
evaluation of polyherbal preparation containg herbal extract of Nigella
sativa (Seeds), Ocimum sanctum (Leaves), Plumeria alba (Leaves) and
Michelia champaca (Stem). The topical gel was prepared and was further
investigated for its analgesic activity using standard diclofenac gel.
Key-Words: Analgesic activity, Topical gel, Herbal extract, Poly herbal
preparations
*Corresponding Author: Suman Gehlot
[email protected], Mob.+91-9893478497
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
43
Formulation and Evaluation of herbal oil for the treatment of arthritis
Sumeet Dwivedi1*, Shailesh Gupta2, Satyaendra Shrivastava3 and
Seema Kohli4
1, College of Pharmacy, Dr. APJ Abdul Kalam University, Indore, (M.P.) -
India
2, Department of Pharmacy, SRK University, Bhopal, (M.P.) - India
3, Swami Vivekanand College of Pharmacy, Indore, (M.P.) - India
4, Pharmacy Department, Kalanikaten Polytechnic College, Jabalpur, (M.P.)
- India
Abstract
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that
primarily affects joints. It typically results in warm, swollen,
and painful joints. Pain and stiffness often worsen following rest. Most
commonly, the wrist and hands are involved, with the same joints typically
involved on both sides of the body. The disease may also affect other
parts of the body. This may result in a low red blood cell
count, inflammation around the lungs, and inflammation around the heart.
Fever and low energy may also be present. Often, symptoms come on
gradually over weeks to months. The concept of use of herbal therapy for
the treatment of RA is as ancient as mankind and civilization. Herbal
medicine and therapy are now-a-days widely used by the common people
because of concept of fewer side effects and with a better safety and
security profile as compared to modern allopathic medication. The present
work was aimed to formulate herbal oil using various herbs viz., satavari,
brahmi, ratanjot, harjod, eucalyptus etc. for the treatment of arthritis.
The formulated herbal oil was evaluated and various parameters such as
viscosity, saponification value, pH etc. were determined and are reported
in this paper.
Key-Words: Herbal oil, Rheumatoid Arthritis, Evaluation
*Corresponding Author: Sumeet Dwivedi
[email protected], Mob.+91-9893478497
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
44
Pharmacognostical, Physicochemical and Chromatographic Evaluation of
Polyherbal Formulation: Navasaya Churna
Dongre Nirmal1*, Dubey P K 2and Shrivastava Virendra3
1 Indore Institute of Pharmacy, Indore.
2 Swami Vivekanand College of Pharmacy, Indore
3 Jaipur National University, Jaipur.
Abstract
Most of the traditional systems of medicines are effective but the need is just
to validate them to assess the quality, quantity and purity of the drugs. To
support the same a polyherbal Ayurvedic powdered formulation Navayasa Churna
which is mentioned in Bhaishajyaratnavali in Pandu roga chikitsa1 and used in the
treatment of Anemeia(pandu),Jaundice(kamala),Heart
diseases(hrdroga),Piles(arsa) and Liver diseases. Navasaya churna is the
composition of Nine ingredients, i.e. Amlaki ,Bibhitaka , Haritaki ,Marica
Pippali,Sunthi,Chitraka,Musta,Vidanga and Lauha bhasma. In the present study a
systematic approach has been evolved and effort has been made to develop well
designed methodology for the standardization of this Formulation. Ingredients
of the formulation, In-house formulation and Marketed formulation were
subjected to organoleptic, microscopic characterization, physico-chemical
analysis and Chromatographic studies. The pharmacognostical evaluation shows
fragments of mesocarp cells, sclereids, tannin contents of Haritaki; Silica
deposition of Amalaki: Unicellular covering Trichomas, stone cells, Rosset cristal
of bibhitaki. In physico-chemical evaluation Tap density, Bulk density, Angle of
repose, Loss on drying, moisture content, ash values viz., acid insoluble ash,
alcohol soluble extractive value, water soluble extractive value as well as pH
value etc. were determined. The Rf values spots obtained in TLC were
determined. The set parameters were found to be simple to evaluate the churna
and can be used as reference standards for the quality control/quality
assurance of Shatavaryadi churna and other related Ayurvedic formulations
comparable to the standards.
Key Words: - Standardisation, Orgenoleptic, Physicochemical.
*Corresponding Author: Nirmal Dongre
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
45
Formulation and evaluation of new nasal drop using Essential Oil of
Black Mustard (Brassica nigra) for the Management of Bacterial
Rhinosinusitis
Harshit Sharma*, Diksha Tomar, Rakesh Patel, Sanjay Jain
Indore Institute Of Pharmacy, Indore (M.P.), India- 453331
Abstract
Plants are very useful and utilized as medicine due to their medicinal properties.
Medicinal plants are great significance to the health of individuals and
communities. Rhino sinusitis is a significant health problem worldwide. It is an
infection of the nasal passages and the paranasal sinus. Purpose of this research,
to formulate the nasal drop by utilization of essential oil of black mustard
(Brassica nigra) , which is used in the management of bacterial rhino sinusitis.
Essential oil of mustard was isolated by simultaneous steam distillation and
extraction. It contain 79.97% of allyl isothiocynate which is the main component
of mustard essential oil which is responsible for very strong pungent odour
which cause irritation on direct application in high concentration. Nasal drops
were formulated containing different concentration of mustard essential oil and
evaluated for its antimicrobial activity against Gram Positive bacteria (S aureus)
and Gram Negative bacteria (E. coli). The essential oil has a broad-spectrum
antimicrobial activity with inhibition zones in the range of 9.43-13.67 mm in the
concentration range from 100-450µg/ml.
Keywords: Antimicrobial activity, Essential oil of black mustard, nasal drop.
*Corresponding Author: Harshit Sharma, [email protected]
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
46
Evaluation of Anti-diabetic activity of Poly Herbal Antidiabetic Tablet
Glucomap
Satyaendra K. Shrivastava1*, Nirmal Dongre2, P.K. Dubey1, B.
Shrivastava3 and Pankaj Sharma3
1. Swami Vivekanand College of Pharmacy, Khandwa Road, Indore (M.P)
2, Indore Institute of Pharmacy, Indore, (M.P.)
2. School of Pharmaceutical Sciences, Jaipur National University, Jaipur
(Rajasthan)
Abstract
Plants used to treat diabetes are of considerable interest as they are
recognizing to contain valuable medicinal properties in different parts of the
plant species with desire properties. Several species of plant are used in the
treatment of diabetes, a disease affecting large number of people worldwide.
The present paper deals with antidiabetic activity of polyherbal tablet
containing herbs viz., Enicostama littorale Blume. (whole plant), Phyllanthus niruri
Linn. (bhooamala), Eugenia jamboloma Linn.(seeds), Eugenia jamboloma
Linn.(leaves), Azadirachta indicaA. Juss. (leaves), Terminalia arjuna(bark), Aegle
marmelos L. Correa (leaves) and Momordica charantiaLinn. (fruits). The
formulation (GT-I) was developed as per standard anti-diabetic tablet glucomap
(GT) and anti-diabetic activity was evaluated in alloxan indued model. The data
of the blood glucose level of rats treated with Alloxan (150mg/kg body weight)
produced diabetes within 72 hours. After 72 hours of Alloxan administered the
blood glucose levels of rats were observed. Results indicate effect of
administration of feeding the GT-I & GTM on body weight and fluid intake in
normal and diabetic rats. Also, effect of administration of feeding the GT-I &
GTM on total hemoglobin and urine sugar in normal and diabetic rats were
reported. The anti-hyperglycaemic effect of the GT-I & GTM on the fasting
blood sugar levels on diabetic rats were recorded. It was revealed in present
investigation that the formulated batch GT-I shows significant anti-diabetic
activity hen compared to standard drug Glibencamide and standard formulation
GT.
Keywords: Anti-Diabetes Medicinal Herbs, Glucomap
*Corresponding Author: Satyaendra Shrivastava,Email: [email protected]
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
47
Tribal medicine’- Antidote to snake venom
Zainab Pandhanawala* and Priya Jain
Swami Vivekanand College of Pharmacy, Indore (M.P.)
Abstract India is a country where most of indigenous tribes exist deep into forest. In the
contemporary world when most of advancements are taking place, these tribes still
rely on the traditional methods using local plants available as an ailment against all
the diseases and wounds.
This abstract focuses on the tribal methods and plants used against Snake Venom,
by various indigenous tribes in India. Snakebite has been a major cause of
mortality across the tropical countries including Indian subcontinent. a variety of
literature sources the data has been compiled mentioning the plants, parts used,
dosage, mode of administration, name of the ethnic communities, geographical
locations etc. depending on the availability of information. Since time immemorial
human society has developed amidst with the plant-life. Snakebite, a medical
emergency encountered in the tropics and estimated 35,000 to 50,000 people die
of snakebite every year in India The common poisonous snakes found in India are
Cobra (Naja naja), Krait (Bangarus caeruleus), Russell's viper (Daboia russelli) and
Saw-scaled viper (Echis carinatus). The report contains plants such as Acanthus
ilcifolius, opium sativum, Barleria cristata etc used by various tribes in
tamilnadu,central india and uttar pradesh etc. To conclude, this aims to attract the
focus of researchers on the pharmacological uses of this plant and contribute
towards the advancement of pharmacy.
*Corresponding Author
National Seminar on“ Potential of tribal medicine to treat life
threatening diseases” on 1st Nov. 2017
Swami Vivekanand College of Pharmacy, Indore, (M.P.) Published Online in International Journal of Pharmacy and Life Sciences, (ISSN 0976-
7126) IF: 4.256; Website: www.ijplsjournal.com, E-mail: [email protected]
48
An institute is As Good As the People Behind it.
Our Faculty Dr. P.K. Dubey
Director
Dr. Shikha Agarwal Mr. Satyendra K. shrivastav Dr. Nimita Manocha Mr. Dishant Gupta ( Vice Principal) (Acedmic Dean) ( Professor) (HOD)
Dr. Priya Jain
Dr. Priya Jain Mr. Rupesh Pandey Mrs. Priyanka Pandey Mrs. Steffy Chandy
(HOD) (HOD) (Assistant Professor) (Assistant Professor)
Miss Pooja Tiwari Mrs. Archana Tiwari Mrs. Khusboo Arora Mrs Dharshan Sharma
(Assistant Professor ) (Assistant Professor ) (Assistant Professor) (Assistant Professor)
Mrs.Pooja Pancholi Miss.Ankita Mane
(Assistant Professor ) (Assistant Professor )