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Natto is back By Dr. Zoltan P. Rona, M.D., M.Sc. A few months ago, I published an article here on three powerful enzymes with significant cardiovascular system benefits. I mentioned that two of them, namely nattokinase and lumbrokinase were not approved for sale in Canada. Health Canada has now had a change of heart and has given an NPN (Natural Product Number) to NAKA products for nattokinase. I am told by NAKA that nattokinase capsules should be on the shelves as early as January 2019. I’m not sure I had anything to do with this but I’ve been complaining about the unavailability of this natural health product in Vitality magazine for nearly a decade. Canadians have been purchasing nattokinase from American web sites or smuggling it across the border up until now. It’s good to know that hard earned Canadian money will no longer be enriching American companies. Death should never be an acceptable side effect of a prescription drug. Yet, that’s exactly what we are seeing with a new wave of blood thinning drugs. Warfarin (rat poison) was a bad enough blood thinner as far as side effects were concerned. With these new chemicals we are seeing even worse outcomes in many cases. The exact number of deaths is uncertain but reports of deaths in the USA are in the thousands. There are thousands of lawsuits already against the drug companies manufacturing these newer blood thinners. Class action lawsuits are also in the works. Despite this, doctors continue to prescribe these at a very high rate. Few, if any, of the patients I’ve followed over the past few years who are on these drugs prescribed by their cardiologists have the faintest idea of how deadly blood thinners can be. Didn’t we have enough drug deaths already with prescription opiates and NSAID’s These newer anticoagulants are designed to prevent strokes in those with heart rhythm abnormalities like atrial fibrillation. Yet, new studies show that they actually increase the risk of stroke. While life threatening conditions like atrial fibrillation require aggressive intervention, using life threatening drugs is clearly not the answer. Natural blood thinners like nattokinase do not increase the risk of stroke in anyone and there is a great deal of ignored evidence of its effectiveness in preventing stroke, blood clots and high blood pressure. Nattokinase will be a boon to those who want to avoid using prescription blood thinners with their deadly side effects. I first heard about it about a decade ago at a lecture by Dr. Jonathan Wright that I attended. He recommends using a dose (100 mg) every 8 hours with fish oils (omega-3). Nattokinase will dissolve dangerously high levels of the clot producing protein called fibrinogen while omega-3 just acts as a lube job for the arteries. Dare I then say that nattokinase combined with omega-3 supplements has all the abilities of a statin drug. What is nattokinase? This is an enzyme isolated from natto, a traditional Japanese food eaten for millennia, made from fermented soybeans. Japanese folklore medicine has traditionally used it for improving cardiovascular health. Studies show that, taken orally, nattokinase can break down and dissolve fibrinogen, a component of blood clots and plaques in the arteries (atherosclerosis). Nattokinase increases the body’s production of plasmin and other thrombolytic enzymes such as urokinase. It improves blood viscosity and circulation in general. Regular use of nattokinase can lower high systolic and high diastolic blood pressure. It also helps optimize blood cholesterol.

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Page 1: Natto is back - TriStar Naturalstristarnaturals.com/wp-content/uploads/2019/01/Tristar-Nattokinase … · namely nattokinase and lumbrokinase were not approved for sale in Canada

Nattois backBy Dr. Zoltan P. Rona, M.D., M.Sc.

A few months ago, I published an article here on three powerful enzymes with significant cardiovascular system benefits. I mentioned that two of them, namely nattokinase and lumbrokinase were not approved for sale in Canada. Health Canada has now had a change of heart and has given an NPN (Natural Product Number) to NAKA products for nattokinase. I am told by NAKA that nattokinase capsules should be on the shelves as early as January 2019. I’m not sure I had anything to do with this but I’ve been complaining about the unavailability of this natural health product in Vitality magazine for nearly a decade. Canadians have been purchasing nattokinase from American web sites or smuggling it across the border up until now. It’s good to know that hard earned Canadian money will no longer be enriching American companies.

Death should never be an acceptable side effect of a prescription drug. Yet, that’s exactly what we are seeing with a new wave of blood thinning drugs. Warfarin (rat poison) was a bad enough blood thinner as far as side effects were concerned. With these new chemicals we are seeing even worse outcomes in many cases. The exact number of deaths is uncertain but reports of deaths in the USA are in the thousands. There are thousands of lawsuits already against the drug companies manufacturing these newer blood thinners. Class action lawsuits are also in the works. Despite this, doctors continue to prescribe these at a very high rate. Few, if any, of the patients I’ve followed over the past few years who are on these drugs prescribed by their cardiologists have the faintest idea of how deadly blood thinners can be. Didn’t we have enough drug deaths already with prescription opiates and NSAID’s

These newer anticoagulants are designed to prevent strokes in those with heart rhythm abnormalities like atrial fibrillation. Yet, new studies show that they actually increase the risk of stroke. While life threatening conditions like atrial fibrillation require aggressive intervention, using life threatening drugs is clearly not the answer. Natural blood thinners like nattokinase do not increase the risk of stroke in anyone and there is a great deal of ignored evidence of its effectiveness in preventing stroke, blood clots and high blood pressure.

Nattokinase will be a boon to those who want to avoid using prescription blood thinners with their deadly side effects. I first heard about it about a decade ago at a lecture by Dr. Jonathan Wright that I attended. He recommends using a dose (100 mg) every 8 hours with fish oils (omega-3). Nattokinase will dissolve dangerously high levels of the clot producing protein called fibrinogen while omega-3 just acts as a lube job for the arteries. Dare I then say that nattokinase combined with omega-3 supplements has all the abilities of a statin drug.

What is nattokinase? This is an enzyme isolated from natto, a traditional Japanese food eaten for millennia, made from fermented soybeans. Japanese folklore medicine has traditionally used it for improving cardiovascular health. Studies show that, taken orally, nattokinase can break down and dissolve fibrinogen, a component of blood clots and plaques in the arteries (atherosclerosis). Nattokinase increases the body’s production of plasmin and other thrombolytic enzymes such as urokinase. It improves blood viscosity and circulation in general. Regular use of nattokinase can lower high systolic and high diastolic blood pressure. It also helps optimize blood cholesterol.

Page 2: Natto is back - TriStar Naturalstristarnaturals.com/wp-content/uploads/2019/01/Tristar-Nattokinase … · namely nattokinase and lumbrokinase were not approved for sale in Canada

Since nattokinase is derived from soy, there are those who will worry about hormone disruptions caused by soy or soy allergy. This is of no concern at all with nattokinase because, when soy is fermented, its effects on hormones are eliminated. What you are getting in a nattokinase supplement is the purified enzyme extracted from natto. There is no soy left in the enzyme supplement.

Most recently, nattokinase has been shown to relieve nasal inflammation, chronic rhinosinusitis (CRS), and nasal polyps. No side effects have ever been reported when nattokinase is taken on its own – without blood thinning drugs, anti-hypertensives, or non-steroidal anti-inflammatory drugs (NSAIDs),

and it does not lower blood pressure in those who usually have normal readings. It is well absorbed from the gastrointestinal tract and does not require injections. There are zero reports of bleeding from anywhere in those using this enzyme on its own.

Potential side effects like excessive bleeding or bruising can occur when nattokinase is taken in conjunction with blood thinning drugs, aspirin, NSAIDs (non-steroidal anti-inflammatory drugs), or anti-hypertensive medication. So, if you are taking any of these drugs on a regular basis, see a natural health care provider who can guide you with using nattokinase.

OTHER NATTOKINASE USES

• Peripheral vascular disease—arterial atherosclerosis or venous thrombosis. Can improve spider veins, hemorrhoids and varicose veins.

• Senile dementia due to poor circulation or cerebral thrombi formation

• Ischemic stroke prevention

• A statin drug alternative

• ASA alternative

• Chronic migraine because platelet aggregation implicated in migraines

• Fibromyalgia, CFS (Chronic Fatigue Syndrome) and Lyme Disease—where chronic infection leads to fibrin deposition

• Dysmenorrhea (painful menses) because excessive clotting can cause painful cramping

• Excessively fast clotting times due to platelet aggregation

• Lowers cholesterol

• Helps with joint and muscle pain

• Bone pain caused by excessive blood clotting

• Breaks down unwanted waste in blood

• Breaks down undigested proteins in the gut

• May help varicose veins, muscle spasms and pain

“Many of us have heard or read about nattokinase, a safe, natural substance proven to prevent and eliminate clots, literally “eating them up.” - Green medicine doctor

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REFERENCES

• The Three Therapeutic Enzymes. http://vitalitymagazine.com/article/top-3-therapeutic-enzymes-effective-relief-for-bowel-problems-joint-pain-heart-disease-and-more/

• Yunqi Weng,1 Jian Yao,1 Sawyer Sparks,2 and Kevin Yueju Wang2,* Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease Int J Mol Sci. 2017 Mar; 18(3): 523. Published online 2017 Feb 28. doi: [10.3390/ijms18030523]

• Nattokinase Information and Research: https://www.betterhealthinternational.com/nattokinase-information-and-research

• Blood-thinning drugs actually increase stroke risk. https://www.theguardian.com/science/2018/feb/15/blood-thinning-drugs-designed-to-cut-stroke-risk-may-actually-increase-it

• Pradaxa linked deaths: https://www.theguardian.com/world/2014/aug/05/drug-safe-deaths-australian-watchdog

• Eliquis deaths: https://www.druginjurylaw.com/eliquis-bleeding-deaths-anticoagulation-irreversible-bleeds-acute-trauma-events-hemorrhages-side-effects/

• Xarelto deaths: https://drugsafetynews.com/2017/08/08/xarelto-injuries-deaths-40-2016/

• Lawsuits against prescription blood thinners: https://www.theexpertinstitute.com/eliquis-may-become-next-blood-thinner-to-spur-class-action-lawsuit/

• Dr. Jonathan Wright on Nattokinase: http://cdn2.hubspot.net/hub/211377/file-519953293-pdf/Nattokinase_-_Optimum_Health_Vitamins.pdf

• Dr. Jonathan Wright quote: http://www.anh-usa.org/reduceyourriskofstroke/

• Dr. Michael Murray quote: http://doctormurray.com/nattokinase-for-nasal-polyps-and-as-a-mucolytic/

• Maruyama M, Sumi H, Effect of Natto Diet on Blood Pressure, JTTAS, 1995

• Sumi H, Hamada H, Nakanishi K,, Hiratani H, Enhancement of the Fibrinolytic Activity in plasma by oral administration of nat-tokinase, Acta Haematol, 1990, 84: 139-43

• Suzuki Y, Kondo K, Matsumoto Y, Zhao BQ, Otsuguro K, Maeda T, Tsukamoto Y, Urano T, Umemura K, Dietary supplementa-tion of fermented soybean, natto, suppresses intimal thickening and modulates the lysis of mural thrombi after endothelial injury in rat femoral artery, LifeSci 2003 73: 1289-98

• Takabayashi T, Imoto Y, Sakashita M, et al. Nattokinase, profibrinolytic enzyme, effectively shrinks the nasal polyp tissue and decreases viscosity of mucus. Allergol Int. 2017 Oct;66(4):594-602.

• Natural health benefits of nattokinase: https://jonbarron.org/herbal-library/nutraceuticals/nattokinase

• Nattokinase a statin drug alternative: https://www.betternutrition.com/natural-rx/statin-alternatives

• Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043915/

• Nattokinase an aspirin alternative: https://articles.mercola.com/sites/articles/archive/2018/10/10/nattokinase-aspirin-alternative.aspx

• Eight Great Nattokinase Benefits: https://www.selfhacked.com/blog/nattokinase/

• Yuko Kurosawa1, Shinsuke Nirengi1, Toshiyuki Homma1, Kazuki Esaki2, Mitsuhiro Ohta3, Joseph F. Clark4 & Takafumi Hama-oka1 A single-dose of oral nattokinase potentiates thrombolysis and anti- coagulation profiles. www.nature.com/scientific reports. 25 June 2015.

• Yung-Yee Chang, Jia-Shou Liu, Shung-Lon Lai, Hsiu-Shan Wu and Min-Yu Lan. Cerebellar Hemorrhage Provoked by Combined Use of Nattokinase and Aspirin in a Patient with Cerebral Microbleeds. Inter Med 47: 467-469, 2008. DOI: 10.2169/internal-medicine.47.0620.

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HEARTHEALTH

Support your

Toronto, ON M9W 5S1www.tristarnaturals.com

V1 (

250c

c) 0

1-19

S É R I E D U P R A T I C I E N

Formulé par

Sans OGMSans GlutenSans K2 Végétalien

Formulé par Formulé par

NattokinaseNattokinase100

mg -

2000 FUs 100

mg -

2000 FUs

P R A C T I T I O N E R S E R I E S

Formulated by

GMO freeGluten freeK2 Free Vegetarian

Formulated by Formulated by

BPA Free Bottle / Bouteille sans BPA60 DP caps d’origine végétale NPN 80089299 60 DR veggie capsules NPN 80089299

Supports Fibrin Degradation and Normal Blood Flow

Soutient la dégradation de la fibrine et le flux sanguin normal

Santé cardiovasculaire

PROUDLY

100

% C A N ADIAN

PROUDLY

100

% C A N ADIAN

Sealed for your protection. Keep out of the reach of children. Do not use if

safety seal is broken or missing. For freshness store in a cool, dry place.

Recommended purpose or use:

• Helps support cardiovascular system health.

Recommended dose: Adults: Take 1 capsule once a

day, or as directed by a health care practitioner. Take on

a empty stomach.

Medicinal ingredients: Each DR veggie capsule contains:

Nattokinase ..........................................100 mg (2000 FUs)

(Enzyme from Natto extract, fermented non-GMO soybean.

FU- Fibrinolytic Units). A delayed release capsule shell

is used for this product to protect the ingredients from

stomach acid and maintain full potency.

Non-medicinal ingredients:Hypromellose, Microcrystal-

line cellulose, Magnesium stearate, Gellan gum. Contains

no added gluten, nuts, eggs, animal products, dairy

products, fish or shellfish, starch, wheat or yeast.

Cautions and warnings: Consult a health care practitioner

prior to use if you have a cardiovascular, kidney, or liver

disorder, or if you are taking any medications.

Contraindications: Do not use if you are pregnant or

breastfeeding. Do not use if you are taking health products

that affect blood coagulation, or if you have a bleeding dis-

order. Stop using this product 7 days before any scheduled

surgery, or immediately if you have unscheduled surgery or

if your suffer from an injury resulting in bruising or bleed-

ing. This product is derived from soy. Do not use if you have soy

allergy.

Scellé pour votre protection. Tenir hors de la portée des enfants. Ne pas utiliser

si le sceau est brisé ou absent. Pour conserver la fraîcheur, garder dans un

endroit frais et sec.

Usages ou fins recommandés :

Aide au soutien de la santé cardiovasculaire.

Dose recommandée : Adultes : Prendre 1 capsule par jour ou

selon les directives d’un praticien de soins de santé. Prendre à jeun.

Ingrédients médicinaux :

Chaque DP capsule d’origine végétale contient :

Nattokinase.............................................100 mg (2000 FUs)

(Enzyme de l’extrait de Natto, soja fermenté sans OGM. FU - Unités

fi brinolytiques). Une gélule à libération retardée est utilisée pour ce

produit afi n de protéger les ingrédients de l’acidité de l’estomac et de

conserver leur efficacité optimale.

Ingrédients non médicinaux : Hypromellose, cellulose micro-

cristalline, stéarate de magnésium, Gomme de gellane. Ne contient

pas de gluten, ni noix, œuf, produit animal ou laitier, poisson ou

crustacé, amidon, blé ou levure.

Précautions et mises en garde : Consulter un praticien de soins

de santé avant l’utilisation si vous avez un problème cardiovascu-

laire, rénal ou hépatique ou si vous prenez des médicaments.

Contre-indications : Ne pas utiliser si vous êtes enceinte ou si

vous allaitez. Ne pas utiliser si vous prenez des produits de santé

qui affectent la coagulation du sang ou si vous souffrez d’un trouble

hémorragique. Arrêter d’utiliser ce produit 7 jours avant la date

prévue de toute intervention chirurgicale ou immédiatement si vous

avez une intervention chirurgicale imprévue ou si vous souffrez

d’une blessure entraînant des ecchymoses ou des saignements.

Ce produit est dérivé du soja. Ne pas utiliser si vous êtes al-

lergique au soja.

DELAYED

RELEASE

À LIBÉRATION

RETARDÉE

Cardiovascular Health

Made in Canada Fabriqué au Canada

tristarnaturals.com The information is intended strictly for research and educational purposes, not as a diagnostic tool or a prescription for any ailment.