nef-mediated suppression of t cell activation was lost in a lentiviral lineage that gave rise to...

8
Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li, Mario L. Santiago, Frederic Bibollet-Ruche, Michaela C. Müller-Trutwin, Francis J. Novembre, Martine Peeters, Valerie Courgnaud, Elizabeth Bailes, Pierre Roques, Donald L. Sodora, Guido Silvestri, Paul M. Sharp, Beatrice H. Hahn, Frank Kirchhoff Cell Volume 125, Issue 6, Pages 1055-1067 (June 2006) DOI: 10.1016/j.cell.2006.04.033 Copyright © 2006 Elsevier Inc. Terms and Conditions

Upload: richard-cranmer

Post on 14-Dec-2015

221 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li,

Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 

Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li, Mario L. Santiago, Frederic Bibollet-Ruche, Michaela C. Müller-Trutwin, Francis J. Novembre, Martine Peeters, Valerie Courgnaud, Elizabeth Bailes, Pierre Roques, Donald L. Sodora, Guido Silvestri, Paul M. Sharp,

Beatrice H. Hahn, Frank Kirchhoff 

Cell Volume 125, Issue 6, Pages 1055-1067 (June 2006)

DOI: 10.1016/j.cell.2006.04.033

Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 2: Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li,

Figure 1

Cell 2006 125, 1055-1067DOI: (10.1016/j.cell.2006.04.033) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 3: Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li,

Figure 2

Cell 2006 125, 1055-1067DOI: (10.1016/j.cell.2006.04.033) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 4: Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li,

Figure 3

Cell 2006 125, 1055-1067DOI: (10.1016/j.cell.2006.04.033) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 5: Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li,

Figure 4

Cell 2006 125, 1055-1067DOI: (10.1016/j.cell.2006.04.033) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 6: Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li,

Figure 5

Cell 2006 125, 1055-1067DOI: (10.1016/j.cell.2006.04.033) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 7: Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li,

Figure 6

Cell 2006 125, 1055-1067DOI: (10.1016/j.cell.2006.04.033) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 8: Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li,

Figure 7

Cell 2006 125, 1055-1067DOI: (10.1016/j.cell.2006.04.033) Copyright © 2006 Elsevier Inc. Terms and Conditions