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Aerospace Physiology Principles of Space Systems Design Aerospace Physiology Review of iterative design approach • Respiratory • Cardiovascular • Musculoskeletal • Vestibular • Neurological © 2001 David L. Akin - All rights reserved http://spacecraft.ssl.umd.edu

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Page 1: Neurological • Vestibular • Musculoskeletal ...spacecraft.ssl.umd.edu/old_site/academics/483F01/13_physiology_p… · Principles of Space Systems Design Short-Term Dose Radiation

Aerospace PhysiologyPrinciples of Space Systems Design

Aerospace Physiology

• Review of iterative design approach• Respiratory• Cardiovascular• Musculoskeletal• Vestibular• Neurological

© 2001 David L. Akin - All rights reservedhttp://spacecraft.ssl.umd.edu

Page 2: Neurological • Vestibular • Musculoskeletal ...spacecraft.ssl.umd.edu/old_site/academics/483F01/13_physiology_p… · Principles of Space Systems Design Short-Term Dose Radiation

Aerospace PhysiologyPrinciples of Space Systems Design

Overview of the Design Process

System-level Design(based on discipline-

oriented analysis)

Vehicle-level Estimation(based on a few

parameters from prior art)

System-level Estimation(system parameters based

on prior experience)

Program Objectives ✑System Requirements

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Aerospace PhysiologyPrinciples of Space Systems Design

Organization of Spacecraft Disciplines• Crew Systems

– Space Physiology– Life Support Systems– Human Factors and Habitability

• Power, Propulsion, and Thermal– Propulsion Systems– Power Generation and Energy Storage– Thermal Analysis and Control

• Avionics Systems– Guidance, Navigation, and Control– Data Management and Information Technologies– Communication Systems

• Loads, Structures, and Mechanisms– Loads Estimation– Structural Analysis– Structures and Mechanism Design

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Aerospace PhysiologyPrinciples of Space Systems Design

Lung Measurements

From Roy DeHart, Fundamentals of Aerospace Medicine, Lea & Febiger, 1985

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Aerospace PhysiologyPrinciples of Space Systems Design

Gas Exchange in the Lungs

From Roy DeHart, Fundamentals of Aerospace Medicine, Lea & Febiger, 1985

Page 6: Neurological • Vestibular • Musculoskeletal ...spacecraft.ssl.umd.edu/old_site/academics/483F01/13_physiology_p… · Principles of Space Systems Design Short-Term Dose Radiation

Aerospace PhysiologyPrinciples of Space Systems Design

Alveolar Pressures

From Roy DeHart,Fundamentals of AerospaceMedicine, Lea & Febiger,1985

Page 7: Neurological • Vestibular • Musculoskeletal ...spacecraft.ssl.umd.edu/old_site/academics/483F01/13_physiology_p… · Principles of Space Systems Design Short-Term Dose Radiation

Aerospace PhysiologyPrinciples of Space Systems Design

Gas Exchange in the Tissues

From Roy DeHart, Fundamentals of Aerospace Medicine, Lea & Febiger, 1985

Page 8: Neurological • Vestibular • Musculoskeletal ...spacecraft.ssl.umd.edu/old_site/academics/483F01/13_physiology_p… · Principles of Space Systems Design Short-Term Dose Radiation

Aerospace PhysiologyPrinciples of Space Systems Design

Effects of Supplemental Oxygen

From Roy DeHart, Fundamentals of Aerospace Medicine, Lea & Febiger, 1985

Page 9: Neurological • Vestibular • Musculoskeletal ...spacecraft.ssl.umd.edu/old_site/academics/483F01/13_physiology_p… · Principles of Space Systems Design Short-Term Dose Radiation

Aerospace PhysiologyPrinciples of Space Systems Design

Hypoxia Effective Performance Time

From RoyDeHart,Fundamentalsof AerospaceMedicine, Lea& Febiger,1985

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Aerospace PhysiologyPrinciples of Space Systems Design

Respiratory Problems

• Hypoxia– Hypoxic– Hypemic– Stagnant– Histotoxic

• Hyperoxia• Hypocapnia• Hypercapnia

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Aerospace PhysiologyPrinciples of Space Systems Design

Types of Hypoxia

• Hypoxic (insufficient O2 present)– Decompression– Pneumonia

• Hypemic (insufficient blood capacity)– Hemorrhage– Anemia

• Stagnant (insufficient blood transport)– Excessive acceleration– Heart failure

• Histotoxic (insufficient tissue absorption)– Poisoning

Page 12: Neurological • Vestibular • Musculoskeletal ...spacecraft.ssl.umd.edu/old_site/academics/483F01/13_physiology_p… · Principles of Space Systems Design Short-Term Dose Radiation

Aerospace PhysiologyPrinciples of Space Systems Design

Oxygen Toxicity

From Roy DeHart, Fundamentals of Aerospace Medicine, Lea & Febiger, 1985

Page 13: Neurological • Vestibular • Musculoskeletal ...spacecraft.ssl.umd.edu/old_site/academics/483F01/13_physiology_p… · Principles of Space Systems Design Short-Term Dose Radiation

Aerospace PhysiologyPrinciples of Space Systems Design

Decompression Sickness

• Release of dissolved gases in blood followingpressure drop

• “DCS”, “Caisson Disease”, “The Bends”• J. B. S. Haldane modeled DCS as

supersaturation of dissolved nitrogen in blood:

• Experience indicates symptomatic DCS onset atlevels of 1.6-1.8

RP

PnominallyN

ambient

= =2 0 79. ( )

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Aerospace PhysiologyPrinciples of Space Systems Design

Vestibular System

From Roy DeHart, Fundamentals of Aerospace Medicine, Lea & Febiger, 1985

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Aerospace PhysiologyPrinciples of Space Systems Design

Vestibular Sense Organs

From Roy DeHart, Fundamentals of Aerospace Medicine, Lea & Febiger, 1985

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Aerospace PhysiologyPrinciples of Space Systems Design

Otolith Responses

From Roy DeHart, Fundamentals of Aerospace Medicine, Lea & Febiger, 1985

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Aerospace PhysiologyPrinciples of Space Systems Design

Cardiovascular

• Cardiovascular deconditioning• Upper body blood pooling• Changes in blood volume• Increased calcium content

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Aerospace PhysiologyPrinciples of Space Systems Design

Artificial Gravity

1

10

100

1000

10000

0 2 4 6

Rotation Rate (rpm)

Lunar gravityMars gravity

0.5*Earth gravity0.75*Earth gravityEarth gravity

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Aerospace PhysiologyPrinciples of Space Systems Design

Short-Term Dose Radiation Effects

• 10-50 rem - minor blood changes• 50-100 rem

– 5-10% minor nausea and vomiting• 100-200 rem

– 25-50% nausea and vomiting– 50% reduction in lymphocytes

• 200-350 rem– Nausea, vomiting, diarrhea, minor hemorrhage– 75% reduction in all blood cells– 5-50% incidence of death

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Aerospace PhysiologyPrinciples of Space Systems Design

Short-Term Dose Radiation Effects

• 350-550 rem– Nausea, vomiting, diarrhea, hemorrhage, emaciation– 75% reduction in all blood cells– 50-90% mortality within 6 weeks– 6 month convalescence

• 550-750 rem– Nausea and vomiting within four hours– Mortality approaching 100%

• 750-2000 - survival time <2 weeks• 2000+ - incapacitation within hours