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New Developments in Novel and Functional Foods
Lisbeth Munksgaard
Senior Manager
Danisco A/S
New Developments in Novel and Functional Foods
Lisbeth Munksgaard
Senior Manager
Danisco A/S
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Lisbeth Munksgaard cv
2007 Senior Manager, External Scientific Affairs, Danisco A/S
2003 Director for Centre for Advanced Food Studies
1999 Danish Feed Administration, Head of Section
1990 National Food Administration, Deputy Head of Department
1979 Dairy Scientist, Project Leader
1978 MSc in Food Science
Member of the ETP-Food for Life Board since 2005
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Content
Danisco A/S
Food for Life Research Strategy
Trends within the Functional Food Market
Regulatory Issues
Concluding Remarks
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1. Danisco – Key Facts
Business: Leading supplier of ingredients and sustainable bio-based solutions
Products: Emulsifiers, Stabilisers, Enzymes, Cultures, Protectants, Sweeteners, Sugar
Industries: Food & Feed, Grain Processing, Cleaning & Textiles, Pharma, Plastics etc.
Turnover: EUR 2.7 billion/DKK 20.3 billion (in 2006/2007)
Employees: 9.700 (July 2007)
Presence: 46 countries
GRINDAMYL™
FloraFit™
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Danisco - A truly global presence
� Sales office
� Innovation centre
� Production plant
CroatiaZagreb �
Czech RepublicSmirice ��
EstoniaTallinn �
HungaryBudapest �
LatviaRiga �
LithuaniaKedainiai �Panevézys �
Vilnius �
PolandOlsztyn ��
Poznan �Warszawa �
RomaniaBucharest �
RussiaMoscow �
Serbia and MontenegroBeograd �
Slovak RepublicBratislava �
UkraineKiev �
EgyptCairo �
South AfricaJohannesburg �Cape Town �
GermanyAnklam �
Frankfurt �Königslutter �Niebüll ���
IcelandReykjavik �
ItalyGranarolo dell'Emilia�Milan �
NetherlandsLeiden ��
Zaandam �
NorwayBryne �
Oslo �
PortugalFaro �
SpainBarcelona ��
Madrid �Valencia �
SwedenArlöv ��
Köpingebro �
Örtofta �
SwitzerlandKreuzlingen ��
UKBeaminster �Lincoln �Marlborough ��
Oxfordshire �
Redhill ��
Stockport �Tullibody �
Wellingborough �
AustraliaSydney ���
ChinaAnyang �Beijing �Guangzhou �Kunshan ���
Shanghai ��
Wuxi �Zhangjiagang �
IndiaHaryana ���
JapanOsaka �Tokyo ��
KoreaSeoul �
MalysiaKuala Lumpur �Penang ���
New ZealandAuckland ���
SingaporeSingapore ���
ThailandBangkok �
AustriaLenzing �
Probsdorf �Vienna �
BelgiumBrugge �
Louvain-La-Neuve �
DenmarkBrabrand ��
Copenhagen ��
Grindsted ��
Haderslev �
Holeby ��
Nakskov ��
Nykøbing �
Tønder �
FinlandHanko �
Jämsänkoski �Jokioinen �
Kantvik ���
Kotka �
Naantali �Säkylä �
Vaasa �
FranceCompiègne �
Dangé Saint Romain ���
Epernon �
Landerneau �
Melle ��
Paris �Roncq �
Sassenage �
Vinay �
CanadaScarborough ���
USAArdsley, NY ��
Bakersfield, CA �Beloit, WI �Cedar Rapids, IA ��
Elmsford, NJ �Fairfield, NJ �Madison, WI ���
New Century Kansas, KS ���
Palo Alto, CA ��
Pine Brook, NJ �Rochester, NY ��
St. Joseph, MI �St. Louis, MO �Terre Haute, IN �Thomson, IL �
ArgentinaArroyito �
Buenos Aires �
BrazilPirapozinho �
São Paolo ��
ChilePargua �
Santiago �
ColombiaBogota ��
GuatemalaGuatemala City �
MexicoApatzingán �
Guadalajara �México City ���
Tecoman ��
Tlalnepantla �Veracruz �
PeruLima �
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Danisco inside ..
.. every 4th loaf of bread
.. every 2nd ice cream
.. every 2nd cheese
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Danisco’s commitment to innovation
897 employees (FTEs) (July 2007)
Research & development 579 (65%)
Application & customer service 318 (35%)
4.3% of annual turnover is invested in innovation
(5.6% in ingredients)
Total: DKK 874 million (€117 million) in 2006/07
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2. ETP Food for LifeHuge global issues in Nutrition
4bn people affected by malnutrition deserve the chance to develop physically & mentally
to get more out of life.
50% of world’s population have blood cholesterol that’s too high.
30% of world’s population have blood pressure that’s too high.
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Obesity – BMI >30
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The Basis of ETP Food for Life
The agro-food sector is the largest
manufacturing sector in Europe with a turnover of 836b € and a positive tradebalance of 5.2b € (2005), but its share of food & drink exports in the world is reducing!
���� need for more “Added value”
The ageing population and
changes in lifestyle and dietary patterns
have increased the incidence of life style diseases
���� need for “Food & health / Add
life to years”
Consumer concerns over food safetyand environmental issues
���� need for “Food you can trust”
and “Sustainable food production”
Pop
ula
tion
nu
mb
ers
Healthy Unhealthy
Target populationfor pharma industries
Target population for food industries & public healthcare
A vision for improving population health:
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ETP ife: Key Challenges of the Strategic Research Agenda
1. Ensuring that the healthy choice is the easy choice for consumers,
2. Delivering a healthier diet,
3. Delivering quality food products,
4. Assuring safe foods that consumers can trust,
5. Achieving sustainable food production,
6. Managing the food chain,
Optimising communication, training and technology transfer.
-
FoodQuality &
Manu-facturing
Food &Health
Food Safety
SustainableFood Production
Food &Consumer
Communication,Training &
Technology Transfer
Food Chain Management
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METABOLIC FUNCTIONS
INTESTINAL andIMMUNE FUNCTIONS
BRAIN FUNCTIONSINFANT
ELDERLY
life-stage
ETP Food for Life: Food and Health Delivering a healthier diet
Understanding consumer behaviour and effective communication in relation to health and nutrition.
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ETP Food for Life
The European private food sector aims at taking a leading position in the food for health marked, but based on sound science
Economic resources for the science base needs priority from public and private sources
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Vitamins
Herbal/BotanicalExtracts
PUFA/speciality
lipids
Phyto-chemicals
Prebiotics Others
• Vit. C• B1, B2, B6, B12• Folic acid• Niacin• Biotin• Panthothenic
acid• Vit. A• Vit. E• Vit. K• Vit. D
• β-Carotene(Provitamin A)
• DHA/EPA• ARA• GLA• CLA• Structured
lipids• Pinolenic
acid
• Phytosterols• Isoflavones• Lignans• Polyphenols
(from berries, olive, tea, tomato, apple,grape, cocoa)
• Tocotrienols• Isothiocyanates
• FOS• Inulin• GOS• Poly-
dextrose• Other oligo-
saccharides(XOS, SOS)
• CoQ10• Glucosamin• Chondroitin• Lipoic acid• Inositol• Creatine• Carnitine• Taurin• SAMe• Choline• Betaine• …
• Gingko• Gingseng• Kava Kava• Saw Palmetto• Horse
Chestnut• Echinacea• St. John’s Wort• Hoodia gordonii
Probiotics
• Lactobacilli• Bifidobacteria• Other cultures
Fibres
• Inulin• Poly-
dextrose• Beta-glucan• Resistant starch• Gums such as
guar gum• Pectins• Resistant
maltodextrin• Psyllium• Insoluble
fibres
Carotenoids
• β-Carotene• Lycopene• Lutein• Zeaxanthin• Astaxanthin
Minerals
• Calcium• Magnesium• Zinc• Iron• Sodium• Potassium• Selenium• Chromium• …
Amino acids,peptidesproteins
• Arg, Glu, Lys• Leu, Ile, Val• Lactoferrin• Immuno-
globulins• Bioactive
peptides• Digestive
enzymes
Polyols
• Xylitol• Lactitol• Isomalt• Maltitol• Erythritol
Not part of food chain
3. TrendsHealth promoting ingredient categories
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3. TrendsFuture health promoting ingredients
Some of the most relevant health promoting ingredients of today and their health benefits for humans have been described more than 30, 50 or even 100 years ago.
Hence, in the near future, there will only be a limited number of really new health promoting ingredients.
Instead, the near future will see:• A much better understanding of the benefits of some of today’s key
health promoting ingredients, and
• Identification of new health benefits for existing health promoting ingredients.
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• Probiotic dairy products
• Bread with n-3-PUFA• Cholesterol-lowering
margarine
• Multi-vitamin tablets• Single entity tablets• Condition-specific
supplements
Increased health effect
Markets
Market Segments
Products
“Better for you” food(improved
profile)
Foods with specific health benefits/claims
OTCPharma-ceuticals
Traditionalfood
(inc. inherent goodness)
Specialnutrition
(e.g. infant, clinical)
Type of Claims
TrendsThe market for health promoting ingredients
• Low fat spreads
• Low sugar bars
• High fibre yoghurt
Functional Food &Beverages
DietarySupplements
Food &Beverages
Nutrition claims
Health claims
Health & nutrition has crossed over from being "just a trend" to being the defining force of future food and beverage strategies.
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TrendsConsumer market drivers for healthy foods
Market sizes for Health & Nutritionfood* 2007 at retail value
Rising incomes Rising incomes and trend foreternal youtheternal youth -> increase demand for health and wellness products.
Increasing awareness of deterioration in personal deterioration in personal
healthhealth, led by busy lifestyles and insufficient exercise. E.g. chronic diseases account for 60% of global deaths.
Increasing incidence of self medicationself medicationand personal personal
responsibilityresponsibility for healthcare.
Obese population turn to better for better for
you productsyou products for weight loss without compromising on taste.
More information from media and authorities have made consumers more educatedmore educated but also often more confusedmore confused around health & nutrition.
Major brands are rere--positioningpositioning towards a more healthy image (e.g. McDonalds)
Claims showing Claims showing
"what is in it for me""what is in it for me"are increasingly important.
*Better for you, functional foods, allergy, herbal, natural, organic, slimming, dietary supplements
• € 344 bn (4.1% CAGR)
• 20% of total food market (€ 1691 bn, 2.7% CAGR)
Source: Euromonitor
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10 key trends for 2008- with the most impact on food industries world wide
1. Digestive health
2. Fruit and super fruit
3. Naturally healthy
4. Beauty foods
5. Weight management
6. Mood foods
7. Premiumisation of food
8. Healthy snacking
9. Kids' nutrition
10.Antioxidants as the new probiotics?
Source: Julian Mellentin, New Nutrition Business
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Examples of products on the market:
Yakult by Yakult Honsha, Japan – probiotic dairy drink (the world's biggest digestive health brand)
Activia and Actimel by Danone – a spoonableyoghurt (the second biggest digestive health brand)
ProViva – a probiotic fruit juice (using a vegetable source bacteria)
Pre-biotics – a new direction of digestive health (added fibres / wholegrain, stimulating the growth and activity of friendly bacteria in the colon).
Pre-biotics primarily promoted in cereals (Kellog's, Weetabix with pre-biotic inulin, Nestlé with whole grain as a natural pre-biotic)
Still low consumer awareness of prebioticsin the US
Products with intrinsic fibre have an increasingly strong position
Trends: 1. Digestive HealthA wellness issue and the biggest opportunity
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Tremds: 5. Weight ManagementMore about maintaining than losing
Satiety (e.g. "Profeel" milk by ValioDairy with calcium and added fibre)
Blocking absorption of fat and sugar
Increasing metabolism
Calorie burning / reducing body fat (e.g. "Enviga" - green tea and caffeine beverage from Nestlé and Coke)
Low or reduced fat / calorie / sugar
Various types of weight
management products:
Sound science around satiety
Easy fit with psychology of food
E.g. (UK) Danone's yoghurt products, "Shape Lasting Satisfaction", based on a combination of fibre (guar gum) and whey protein
Most effective NPD will be:
Satiety
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Trends: 8. Healthy SnackingFor the "me" generation
Market drivers:
The boundaries between health, convenience and indulgence are breaking down
Traditional meal occasions and family meals are diminishing, on-the-go food, longer working hours, single parent families etc.
Demand for indulgent snack without guilt and without compromising on taste or convenience
Factors for success:
Excellent taste
Extreme convenience
Single-serve (high growth in bars and single-serve beverages)
No limits on innovation in packaging, ingredients or product forms
Any material that can be dried, extruded, frozen, shaped, poured, pureed to deliver a good-tasting healthy food snack
212121
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Trends: 8. Healthy snackingFor the "me" generation
Product examples:
"Flat Earth" by PepsiCo (Frito-Lay) – a range of fruit and vegetable chips
Roasted Vegetable Ritz crackers by Kraft
"Up-and-Go" by Sanitarium – a breakfast cereal drink
"Innocent" smoothies
Knorr Vie by Unilever (2 portions of the recommended 5-a-day)
Fruit2Day by Hero (2 portions of the recommended 5-a-day)
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10 key trends for 2008- where can Danisco help?
1. Digestive health
2. Fruit and super fruit
3. Naturally healthy
4. Beauty foods
5. Weight management
6. Mood foods
7. Premiumisation of food
8. Healthy snacking
9. Kids' nutrition
10.Antioxidants as the new probiotics?
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Targeted
Lifetime
Risk reduction Prevention Treatment
Build-microflora-immunity
Acute (drug)-specific-advanced
Prevent-biomarkers of complications
-e.g., cholesterol, hypertension
Balance-protect-maintain
Healthier foodsFunctional foodsFood SupplementsSpecial nutritionClinical nutritionNutraceuticals
(Cosmeceuticals)
NEW PARADIGM- population of actives- multiple effects- low efficacy- LT additive
HUMAN CLINICAL- single compound- single effects- high efficacy- ST intervention
+ GENOMICS (ind.var.) - GENOMICS (one size..)
’The clinicaldogma’
4. Regulatory IssuesHealthy Bioactives in the Food—Drug Interphase
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Regulation
Harmonisation of Health Claims Regulation is welcomed
Food safety is a technical issue which all stakeholders would support to be met
Food ingredients for health do not have strong clinical effects like drugs, but long term health promoting effects. Valid biomarkers should be identified for testing the benefits of functional ingredients rather than clinical trials
Regulation should be based on sound science
Regulation may need a “health check” for being prepared for innovations and for balancing risks and benefits
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RegulationExample Grindsted® Soft N Safe
Grindsted®Soft N Safe is a plasticizer based on vegetable oil, and can be used to replace critical substances in plastics like phthalates.
It has an exceptional safety profile, with a NOAEL of 5000 mg/ kg bw.
The substance cannot comply with the OML of 60 mg/kg, but the migration of the substance is of no safety concern.
The current legislation on plastics is an obstacle to the use of a safe and sustainable alternative to other plasticizers.
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5. Concluding Remarks
Public and private funding dedicated for research within food for health area is essential for sound science based regulation
Functional food is food and not drugs. Valid biomarkers should be identified for testing the benefits of functional ingredients rather than clinical trials
Future regulations of the area should balance risks and benefits in order to avoid built-in barriers for new beneficial products
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Thank you for your attention
Thanks to
Caroline Herody
Lisa Jensen
Oliver Hasselwander
Signe Ørberg