new protein structure could help treat alzheimer´s, related diseases and when temperatures get...
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NEW PROTEIN STRUCTURE COULD HELP TREAT ALZHEIMER´S, RELATED DISEASES AND WHEN TEMPERATURES GET COLD, NEWLY-DISCOVERED PROCESS HELPS FRUIT FLIES COPE.
MANUELA VALENCIA BOTEROMedicine Student
3rd SemesterUPB
FOLDING
INTRODUCTION• Today the molecular biology is
the starting point to know the form which difference pathology work in the human's body.
• The amyloid disease are each time most frequently because part of a process that pass in all bodies.
• A one gen in the drosophila permit maintain the temperature in blood-cold animals.
Date: July 28, 2014.
Source: University of
Washington
NEW PROTEIN STRUCTURECOULD HELP TREAT
ALZHEIMER´S,RELATED DISEASES.
NEW PROTEIN STRUCTURECOULD HELP TREAT ALZHEIMER´S,
RELATED DISEASES.
In the all bodies which age, some proteins change the normal state to abnormally folded, and accumulate in some tissues, but does not happen quickly.
This are nominated
amyloid fibrils.
NEW PROTEIN STRUCTURECOULD HELP TREAT ALZHEIMER´S,
RELATED DISEASES.
The amyloids fibrils possibly pass to a toxic state quickly and produce the amyloids diseases.
The amyloids diseases include Parkinson's, Alzheimer's, heart disease and type 2 diabetes.
NEW PROTEIN STRUCTURECOULD HELP TREAT ALZHEIMER´S,
RELATED DISEASES.
The researchers found a one peptide nominate “"alpha sheet“. This is
able to stop the passage the active protein to
toxic protein.
This will produce the decrease of the effects of these diseases or at
least progress and accurate diagnosis of
disease
NEW PROTEIN STRUCTURECOULD HELP TREAT ALZHEIMER´S,
RELATED DISEASES.
Each step in the research is a progress
in search of the solution of the disease, and in this case the hope of a better quality of life for
patients.
The accurate diagnosis of the disease will do to
better treatment and thus avoid treating these diseases to be
widespread.
WHEN TEMPERATURES GET
COLD, NEWLY DISCOVERED PROCESS
HELPS FRUIT FLIES COPE.
Date:
July 21, 2014.
Source: University of
Rochester
WHEN TEMPERATURES GET COLD, NEWLY DISCOVERED PROCESS
HELPS FRUIT FLIES COPE.
The blood-cold animals does not
have a mechanism to regulate its corporal
temperature
In this extreme temperature the cells
are stressed and some biological
processes in the cell are slowed down more than others.
WHEN TEMPERATURES GET COLD, NEWLY DISCOVERED PROCESS
HELPS FRUIT FLIES COPE.
A researchers discover the internal
mechanisms of the egg cell of the fruit fly,
known as Drosophila.
The productions of proteins is a
fundamental process in the cells, a type of
assembly line carries raw materials from the nucleus to the posterior
end of the egg cell where the proteins are
synthesized
WHEN TEMPERATURES GET COLD, NEWLY DISCOVERED PROCESS
HELPS FRUIT FLIES COPE.
When temperatures drop, the rate at
which the proteins are built is slow
significantly more than the rate at which the raw materials are
delivered
A protein nominated “klar” decreases the
rate at which proteins are
delivered, to be proportional
conduction and production.
A one of the protein that are syntethized denominate
“oskar”, It is essential to put the tail in the right place.
Only when Klar was present did the fruit fly
develop properly
WHEN TEMPERATURES GET COLD, NEWLY DISCOVERED PROCESS
HELPS FRUIT FLIES COPE.
This study demonstrates that humans do not possess the same
mechanism but if a similar, and perhaps could be used for places where
the temperature is extreme.
Medical utility
The discovery of the protein from the gene that
synthesizes makes it easier to correct disorders
permanently or used for genetic manipulation.
Detect the exact spot that develops a disease makes the
research is successful, allowing the development of
new techniques and drugs that promote the exact need of the
patient.
Medical utility
Medical utility
More and more diseases and modes of resistance
arise, which is why research should be
increasingly demanding, and go beyond.
Animals are often the starting point and
experiment to reach breakthroughs, and no
matter what species is, any discovery can be a big step
for medicine.
Medical utility
The disease that has no solution will always be catastrophic from anywhere display, but how are you arise when solutions becomes
easier to treat patients even from the psychological aspect.
Although the investigation from the outset not have a medical use to future development of these can promote strides for humanity,
including the discovery of this gene or the protein that maintains a coordinated certain temperature control may eventually be used in
medicine and to be a benefit.
Even I would say that researchers are the chaperone of medicine.
BIBLIOGRAPHY
•SCIENCE DAILY. New protein structure could help treat Alzheimer's related diseases•SCIENCE DAILY. When temperatures get cold, newly—discovered process helps fruit flies cope. Voet, Donald; Voet, Judith. voet bioquímica. 3. Ed. Buenos Aires. Editorial medica panamericana. 2006. Páginas 318-321
