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NewsBrief October 2017

Other Events of Interest click links for details Oct. 16, 12-1 PM: Heart, Lung and Vascular Institute Seminar Series. Multi-Tasking By the Sarcomere/Cytoskeletal Network of Heart Mus-cle. R. John Solaro, PhD, Univer-sity of Illinois at Chicago College of Medicine. 3351 UC MSB. Oct. 16, 12-1 PM: Immunohema-tology Club Research Seminar Series. Microenvironment and polar-ity in hematopoietic stem cells: new insights. Jose Cancelas, MD, PhD, stem cell program leader, Cincinnati Children’s. Cincinnati Children’s Research Auditorium, Location R3381. Oct. 16, 2-3 PM: Perinatal Insti-tute Seminar. The Neonatal Micro-biome in Health and Disease. Barbara B. Warner, MD, Washing-ton University in St. Louis School of Medicine. Cincinnati Children’s Re-search Auditorium, Location R3381. Oct. 17, 12-1 PM: Molecular Ge-netics, Biochemistry & Microbiol-ogy Weekly Seminar Series. The Cytomegalovirus GPCRs: Signaling and Effects on Viral Dissemination and Persistence. William Miller, PhD, molecular genetics, UC Col-lege of Medicine. 3351 UC MSB. Oct. 17, 12-1 PM: Digestive Health Center Seminar Series. Reprogramming of Foxl1+ Hepatic Progenitor Cells and Angiogenesis. Soona Shin, PhD, pediatric gen-eral and thoracic surgery, Cincinnati Children's. CCHMC Location S6.125. Oct. 18, 12-1 PM: Cincinnati Chil-dren's Research Foundation Sem-inar Series. Spatial fold-change of cell signaling encodes positional information for pattern formation. Ertugrul Ozbudak, PhD, develop-mental biology, Cincinnati Chil-dren’s. CCHMC Research Auditori-um, Location R3381. Oct. 19, 12-1 PM: Internal Medi-cine Research Conference. Im-mune mechanisms of resistance to anti-PD1 therapy in head and neck cancer patients. Laura Conforti, PhD, nephrology and Trisha Wise-Draper, MD, PhD, hematology on-cology, UC College of Medicine. 6254 UC MSB. Oct. 19, 12-1 PM: Faculty Re-search Crosstalk. Deciphering and Modeling Human Congenital Cranio-facial Malformations: A Genetic Ap-proach. Nicole Weaver, MD, hu-man genetics, Cincinnati Children’s. Sabin Auditorium, Location D1.23. Oct. 19, 2-4 PM: Project Manage-ment and Design in REDCap. Cin-cinnati Children’s Location S3.110. Oct. 20, 11 AM-12 PM: Biomedical Informatics Hutton Lecture Se-ries. The fun (and challenges) of clinical research informatics. David Hanauer, MD, MS, University of Michigan. Cincinnati Children’s Lo-cation S10.130. Oct. 23: Data! Fostering Health Innovation in Kentucky and Ohio. Conference showcasing novel and effective uses of health data in the region. Presented by Interact for Health and Foundation for a Healthy Kentucky. St. Elizabeth Training and Education Center, Erlanger. Oct. 23, 12-1 PM: Immunology Seminar Series. Enhancing control of Mycobacterium tuberculosis infec-tion with single-cell resolution. Bry-an D. Bryson, PhD, Harvard School of Public Health, Cincinnati Children’s Research Auditorium, R3381. Oct. 24, 12-1 PM: Molecular Ge-netics, Biochemistry & Microbiol-ogy Weekly Seminar Series. Structure and Function of Notch Transcription Complexes: Where we have been and where we are going. Rhett Kovall, PhD, molecular ge-netics, UC College of Medicine. 3351 UC MSB. Oct. 25, 12-1 PM: UC Dept of Psy-chiatry Lurie Lecture. Advances in the Management of Alzheimer’s Pre-vention and Treatment: A Clinical Precision Medicine Approach. Rich-ard Isaacson, MD, Weill Cornell Medical College. Oct. 26, 10-11 AM: Dermatology Grand Rounds. Advances in target-ed therapy for psoriasis and atopic dermatitis: a bench-to-bedside suc-cess story. Andrew Blauvelt, MD, MBA, Oregon Medical Research Center. G344 Hoxworth Bldg. Oct. 26, 1-2 PM: Translational Cancer Research Seminar Series. The Golden Triangle of Outcomes Guided Proton Therapy. Antony Lomax, PhD, Paul Scherrer Insti-tute, Switzerland. Cincinnati Chil-dren’s Research Auditorium, Loca-tion R3381. Oct. 27, 11 AM-12 PM: Biomedical Informatics Hutton Lecture Se-ries. Understanding cell decision making with mechanistic modeling and machine learning. Tongli Zhang, PhD, pharmacology and systems physiology, UC College of Medicine. Cincinnati Children’s Lo-cation S10.130. Oct. 30, 12-1 PM: Heart, Lung and Vascular Institute Seminar Series. Life on the Edge: Mitochondria, Emergence and Heart Disease. Brian O´Rourke, PhD, Johns Hop-kins University School of Medicine. 3351 UC MSB. Oct. 30, 12-1 PM: Center for Tech-nology Commercialization Semi-nars with Industry Series. The Evolution of a Biomedical Device Company from Concept to Corpora-tion. Mike Hooven, Enable Injec-tions, Inc. Cincinnati Children’s Re-search Auditorium, Location R3381. Oct. 30-31: 6th Annual Appalachi-an Translational Research Net-work (ATRN) Health Summit. Transforming Health in Appalachia Through Engaged and Translational Research. Hosted by the Penn State Clinical and Translational Sci-ence Institute. Hershey Lodge, Her-shey, PA. Nov. 6, 12-1 PM: Academic Af-fairs and Career Development Seminar. Strategies for marketing yourself and your science. Kate Setter, Tim Bonfield, and Nick Miller, marketing and communica-tions, and Jill Williams, biomedical informatics, Cincinnati Children's. Location S1.204.

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CCTST Deadlines Approaching Oct 31: Pilot Translational Research and Innovative Core Grant Program. Provides up to $60,000 for projects by estab-lished principal investigators or mentored new/early stage investi-gators focused on applying discoveries generated during re-search in the laboratory, and in pre-clinical studies, to the devel-opment of trials and studies in humans. The Program also pro-vides up to $50,000 for the establishment of new, innovative cores with a clear translational focus. Letters of intent are due Tuesday, October 31 before 5 PM. Nov 1: Clinical Research Feasibility Fund (CReFF) Provides up to $20,000 for junior faculty on a clinical research career path who are utilizing substantive resources of the Schu-bert Research Clinic for pilot studies. Approved protocol required. Applications are due Wednesday, November 1 by 12 noon. Nov 1: Just-in-Time Core Grant Program. Provides up to $7,500 for investigators to use UC or CCHMC core facilities to obtain critical data for submission of a competitive extramural proposal, patent application or commercialization agreement. Ap-plications are due Wednesday, November 1 by 5 PM. Looking for more? Visit the CCTST intramural Funding Opportu-nities page. For extramural options, check out SPIN, the world’s largest database of sponsored funding opportunities!

CCTST Grand Rounds October 27 From Quality Control to Disease Screening and Surveillance is the topic of the next CCTST Grand Rounds, Friday October 27 from 12-1 PM in Room 2351 of the UC Medical Sciences Building (MSB). Featured speaker is Peihua Qiu, PhD, professor and founding chair of the Department of Biostatistics at the University of Florida. Dr. Qiu’s talk will explain some basic concepts and methods about quality control; help participants recognize the risks of using statis-tical methods without checking their assumptions properly; and describe some recent methods used for disease screening and surveillance. CME is offered. Lunch is available to CCTST members (join free of charge) who register here by October 24. Read more

Community Engagement Speaker Series November 14-15 Please join us for the CCTST Community Engagement Fall Speaker Series, co-sponsored with the Center for Pediatric Ge-nomics at Cincinnati Children’s. Featured speakers are Alondra Nelson, PhD, Dean of Social Science and Professor of Soci-ology at Columbia University, and Vence Bonham, JD, Senior Advisor to the National Human Genome Research Institute Direc-tor on Genomics and Health Disparities. Community Dinner and Awards Ceremony, Nov 14 Dr. Nelson will discuss her book The Social Life of DNA: Race, Reparations, and Reconciliation After the Genome, 5:30 PM No-vember 14 at Cincinnati Music Hall. Recipients of this year’s Community Advocacy, Partnership and Research Awards will also be recognized. Community Forum, Nov 15 Mr. Bonham will discuss how new genomic knowledge impacts community health and how to eliminate disparities from 8:30-11:00 AM in Cincinnati Children’s Medical Education and Re-source Center (MERC), Rooms 1103-1104, Oak Campus. Break-fast is provided. Free parking. Community Grand Rounds, Nov 15 Mr. Bonham will discuss health equity and precision medicine with a panel of local genomic and ethics experts from 12-1 PM in the MERC Auditorium. Lunch is provided. The program will be live streamed. More information will be available soon. Please contact Stacey Gomes if you have questions.

Alondra Nelson, PhD

Nominations for CCTST Community Awards Due Oct. 16 The CCTST Community Advocacy, Partnership and Research Awards honor excellence in leadership, collaboration, and health promotion in the Greater Cincinnati/Northern Kentucky re-gion. Deadline for nominations is Monday, October 16. Winners and nominators will be notified by October 27. Awardees will be recognized at the CCTST Community Dinner and Awards Cere-mony, November 14 at Music Hall. Categories are:

Community Health Advocate Award

Academic-Community Research Partnership Award

Academic-Community Partnership Student Award

Practice-Based Research Award Please see the Call for Nominations for complete details. Read more

Save the Date for These CCTST Events Nov 30, 9-11 AM: CCTST Regulatory Forum Managing multi-site research in Greater Cincinnati. Topics to include single IRB review, executing clinical trial agreements, recruitment across sites, data management concerns, and build-ing relationships. 2351 UC MSB. Dec 15, 11 AM-1 PM: CCTST Grand Rounds Dissemination and implementation science. Elaine Morrato, DrPH, Interim Dean and Associate Dean for Public Health Prac-tice, Colorado School of Public Health, University of Colorado and Kathleen Walsh, MD, MSc, Director of Patient Safety Re-search, Anderson Center, Cincinnati Children’s. 2351 UC MSB.

Peihua Qiu, PhD

Community Health Grant Information Session October 19 Interested in applying for a CCTST Community Health Grant, Part-nership Development Grant, or the Community Leaders Institute? Plan to attend an Information Session on Thursday, October 19 from 3:30-5:00 PM in Room A of the United Way Convening Center, 2400 Reading Road, Cincinnati. Learn about the application process and requirements, and hear testimonials from past grantees and CLI grads! Refreshments will be served. Potential applicants are encouraged but not required to attend. Read more

Vence Bonham, JD

CCTST Pilot/Training Leadership Updates The CCTST Pilot Translational and Clinical Studies (PTC) Core is now co-directed by James Geller, MD, professor of pediatrics and medical director, Kidney and Liver Tumors Program, Cincin-nati Children’s, and Dennis McGraw, MD, associate professor, pulmonary, critical care and sleep medicine, UC College of Medi-cine, and director, pulmonary medicine, Cincinnati VA Medical Center. The KL2 Research Scholars Career Development Award Pro-gram is now led by director Jessica Kahn, MD, MPH, professor of pediatrics and director of the Office of Academic Affairs and Ca-reer Development, Cincinnati Children’s and associate director Jason Blackard, PhD, associate professor of digestive dis-eases and director of the Office of Global Health, UC College of Medicine. The TL1 National Research Service Award Training Core to be included in the next CTSA renewal submission (May 2018) will be led by Margaret Zeller, PhD, professor of pediatrics and co-director, Center for Child Behavior and Nutrition Research and Training, Cincinnati Children’s; E. Melinda Mahabee-Gittens, MD, MS, professor of pediatrics and attending emergency medicine physician, Cincinnati Children’s; and Alex Lentsch, PhD, senior associate dean for faculty affairs and development, UC College of Medicine. The Core will offer predoctoral students an orientation to translational science, and postdoctoral appoin-tees advanced research training aligned with the CTSA goals of advancing therapeutics (drugs, devices, and preventatives), clini-cal interventions, and behavioral modifications to improve health.

2016 Awardee Dominique Love

Elaine Morrato, DrPH