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NHGRI GWA Catalog www.genome.gov/GWAStudies Published Genome-Wide Associations through 12/2010, 1212 published GWA at p< 5x10 -8 for 210 traits

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Page 1: NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010_4.pdf · O LP (a) levels O LpPLA(2) activity and mass Lung cancer Magnesium levels Major mood disorders Malaria O Male

NHGRI GWA Catalogwww.genome.gov/GWAStudies

Published Genome-Wide Associations through 12/2010, 1212 published GWA at p<5x10-8 for 210 traits

Page 2: NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010_4.pdf · O LP (a) levels O LpPLA(2) activity and mass Lung cancer Magnesium levels Major mood disorders Malaria O Male

Second-Generation Sequencing Introduction to second-generation sequencing …users.umiacs.umd.edu/~hcorrada/CMSC858B/lectures/lect22... · 2012-02-27 · ionTorrent 21 Oxford Nanopore

A,) \.l~'~ vw \\ dt~-\-0S'--\-,U0 (r,~0)The" href="https://vdocument.in/0-uj-hcorradacfglectureslect7differentialexpressionii-loj1-r-vrj.html">~0( UJ - CBCBcbcb.umd.edu/~hcorrada/CFG/lectures/lect7_DifferentialExpressionII/... · \L{(_oJ1 r-vrJ~ ~"J~ ~ \:)(\ ~0(./'(bJ ~J::: UJ II> A,) \.l~'~ vw \\ dt~-\-0S'--\-,U0 (r,~0)The

Chapter(03(–Linear(Regression( - UMIACSusers.umiacs.umd.edu/~hcorrada/IntroDataSci/lectures/Regression.pdf · Chapter(03(–Linear(Regression(Slides(by(ZiaKhan(Simple(Linear(Regression(0

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CMSC858P: Statistical learning background - CBCBhcorrada/CMSC858B/lectures/lect3/StatLearn... · CMSC858P: Statistical learning background ... gender, ethnicity, etc. Note: ... In

RNAseq: isoform expression quantiﬁcation and transcript …users.umiacs.umd.edu/~hcorrada/CMSC858B/lectures/lect13/... · 2012. 3. 5. · transcript assembly Slides courtesy from

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Lecture 2: Linear methods for regressionusers.umiacs.umd.edu/~hcorrada/PracticalML/pdf/lectures/...Lecture 2: Linear methods for regression Rafael A. Irizarry and Hector Corrada Bravo

PATTERN’RECOGNITION’’ AND’MACHINE’LEARNING’cbcb.umd.edu/~hcorrada/PML/pdf/lectures/prml-slides-8.pdf · prml-slides-8.ppt Author: Hector Corrada Bravo Created Date: 11/26/2012

Gene Expression Analysis with R and Bioconductor: …legacydirs.umiacs.umd.edu/~hcorrada/CFG/lectures/lect21...Gene Expression Analysis with R and Bioconductor: from measurements to

Gene expression analysis with R and Bioconductorusers.umiacs.umd.edu/~hcorrada/CFG/lectures/lect21... · Gene expression analysis with R and Bioconductor: from measurements to annotated

Lecture 3: Linear methods for classi cationcbcb.umd.edu/~hcorrada/PracticalML/pdf/lectures/...Lecture 3: Linear methods for classi cation Rafael A. Irizarry and Hector Corrada Bravo

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NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010...O LP (a) levels O LpPLA(2) activity and mass Lung cancer Magnesium levels Major mood disorders Malaria O Male pattern

Analysis of Diﬀerential Gene Expression Studieshcorrada/CMSC858B/readings/Solutions_ch14.pdf · a case study of the estrogen data in Section 14.3.1. 14.2 Diﬀerential expression

Examining the Relative In uence of Familial, Genetic and ...hcorrada/papers/tr1148_ssanovaped.pdf · Genetics and Ophthalmology Case Western Reserve University Cleveland, OH 44106

Ensemble(Methods( - UMIACSusers.umiacs.umd.edu/~hcorrada/PracticalML/pdf/lectures/EnsembleMethods.pdfDeﬁnion EnsembleClassiﬁca.on Aggrega

CMSC858B: Computational systems biology and functional ...users.umiacs.umd.edu/~hcorrada/CMSC858B/lectures/lect1/CMSC858P_Lecture1.pdfCMSC858B: Computational systems biology and functional

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LWF-Fläche Chironico...o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o

Second-Generation Sequencing Introduction to second-generation sequencinghcorrada/CMSC858B/lectures/lect… · · 2012-02-27second-generation sequencing CMSC858B Spring 2012

PATTERN’RECOGNITION’’ AND’MACHINE’LEARNING’users.umiacs.umd.edu/~hcorrada/PML/pdf/lectures/prml-slides-8.pdf · The(SumPProductAlgorithm((8)(To(compute(local(marginals:(•

Stanford University · O o o o o o o O o o o o o o o o o o o o o O o o o O o o o o O O o O o o . o o o o o O o o o o o o O o o o O o n o O o o o o o o o o o O o o o O o

A statistical framework for modeling gene expression …hcorrada/CMSC858B/readings/svmIntegrate.pdf · A statistical framework for modeling gene expression using chromatin features

A super quick introduction to molecular biology and genomicsusers.umiacs.umd.edu/~hcorrada/CMSC423/lectures/... · A super quick introduction to molecular biology and genomics Héctor

O Ln OO O O CO O O O O O O O O O O O O O O O O O O O O O O O … · O Ln OO O O CO O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O

Genotype-Phenotype Association - UMIACSusers.umiacs.umd.edu/~hcorrada/CFG/lectures/lect16_gwas/gwas.pdf · Genotype-Phenotype Association CMSC702 Spring 2014! Hector Corrada Bravo!

Examining the relative inﬂuence of familial, genetic, and ...hcorrada/CMSC858B/readings/bdes.pdf · risk models Héctor Corrada Bravoa,1, ... Sudha K. Iyengarc, and Grace Wahbad,1

Cluster Analysis of Genomic Data - University Of Marylandcbcb.umd.edu/~hcorrada/CFG/readings/Solutions_ch13.pdf · Cluster Analysis of Genomic Data ... we generalize the output of

Lecture 5: Model selection and assessmentusers.umiacs.umd.edu/~hcorrada/PracticalML/pdf/lectures/selection.pdfIn this Chapter we describe some in-sample methods for model selection

Cluster Analysis of Genomic Datausers.umiacs.umd.edu/~hcorrada/CFG/readings/Solutions_ch...clustering algorithm, consider the output if the algorithm were applied to the data generating

Gene Expression Analysis with R and Bioconductor: …cbcb.umd.edu/~hcorrada/CFG/lectures/lect21_bioc/bioconductor.pdf · Gene Expression Analysis with R and Bioconductor: from measurements

Lecture 5: Model selection and assessmentlegacydirs.umiacs.umd.edu/~hcorrada/PracticalML/... · Although the least squares estimate is the linear unbiased estimate with mini-mum variance,

Gene Expression Analysis with R and Bioconductor: from ...users.umiacs.umd.edu/~hcorrada/CFG/lectures/lect21_bioc/bioconductor.pdf · postulated that gene expression profiles of the

Lecture 7: Smoothingusers.umiacs.umd.edu/~hcorrada/PracticalML/pdf/lectures/smoothing.pdf · Lecture 7: Smoothing Rafael A. Irizarry and Hector Corrada Bravo March, 2010 Kernel Methods