nih electronic multi-project applications: annotated sf424

NIH Electronic Multi-project Applications: Annotated SF424 (R&R) Form Set

Forms-C Series

Multi-project applications are comprised of Overall application information, one or more sets of Component information and system-generated summary information. Although data will be collected through ASSIST or other system-to-system solutions instead of downloadable forms, the data collected are the same data fields found on the SF424 R&R Adobe forms currently used for NIH single-project applications. The data collected at the Overall application level are the same for all multi-project applications. The data items collected for components will depend on component type and may vary from one component to another.

Forms Currently Supported for Multi-project Applications

Data Collection Overall Other Named Components Page # SF424 R&R cover

Subset of data items 2

PHS 398 Cover Page Supplement 4 R&R Other Project Information 6 Project/Performance Sites 7 R&R Sr/Key Person Profile (Expanded)

8

R&R Budget (All components except NRSA-Training.)

9

R&R Subaward Budget Attachment

(Optional for all components except NRSA-Training.)

13

PHS 398 Research Plan (All components except Indiv Career Dev, Inst Career Dev,

and NRSA-Training.)

14

Planned Enrollment Report (Optional for all components except NRSA-Training.)

15

Cumulative Inclusion Enrollment Report

(Optional for all components except NRSA-Training.)

16

PHS 398 Career Development Award Supplemental Form

Indiv Career Dev component only. 17

PHS 398 Training Budget NRSA-Training component only. 19 Training Subaward Budget Attachment Form

NRSA-Training component only. 21

PHS 398 Research Training Program Plan

Inst Career Dev and NRSA-Training components only.

23

PHS Additional Indirect Costs (Optional)

24

Important Note The Application Guide and Supplemental Instructions found at http://grants.nih.gov/grants/funding/424/index.htm and the announcement text for the target Funding Opportunity Announcement (FOA) remain the official documents for defining application requirements. This resource is meant to compliment, not replace, those documents.

FORMS-C Series (Footer not part of forms) Updated: March 25, 2015

http://grants.nih.gov/grants/funding/424/index.htm

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µ 1 � ¯ ¯ ¶ � � � � � � � � � · ³ � � � � � � � � � � l � � � � � � � ± � ¸ ¹ º » ¼ ½ » ¾ ¹ ¿À ¹ Á » Â Ã ¾ ¹ Ä Ã ¿ À Å Æ Å Ç Å È Ä ¿É Ã Â ¹ ¹ Ã Ê ¿É Ã Â ¹ ¹ Ã Ë ¿Ì Å Ã Í ¿É Ã » Ã ¹ ¿ Î Ï Ð Ñ Ð È Ç Ã » ¼ Ì È Ò ¹ ¿Ì È Ó Ä Ã Â Í ¿Ð ¹ Â Ç È Ä Ã È Ô ¹ Õ È Ä Ã » Õ Ã ¹ Ò È Ä ¾ » Ã Ã ¹ Â Ç Å Ä Æ È ¼ Æ Å Ä º Ã Ö Å Ç » Á Á ¼ Å Õ » Ã Å È Ä× Å Â Ç Ã ½ » ¾ ¹ ¿ Ø Å Ò Ò ¼ ¹ ½ » ¾ ¹ ¿¸ » Ç Ã ½ » ¾ ¹ ¿ É Ó Ù Ù Å Ú ¿Ð Ö È Ä ¹ ½ Ó ¾ Ô ¹ Â ¿ × » Ú ½ Ó ¾ Ô ¹ Â ¿Û ¾ » Å ¼ ¿Ü 1 ° ³ ¯ ¶ � 6 ° · � � ° � � � � � � � � � � � Ý Þ ß à á â ã Ý ä ß à á åæ 1 � 6 ¯ ° � � � ¯ ¯ ¶ � � � � � ç Ã Ö ¹ Â è É Á ¹ Õ Å Ù Í é ¿ ê È ¾ ¹ Ä ç ë Ä ¹ Ò É È Õ Å » ¼ ¼ Í » Ä Ò Û Õ È Ä È ¾ Å Õ » ¼ ¼ Í À Å Ç » Ò Æ » Ä Ã » º ¹ Ò � � � � ² � � � � � � � � � � � � l � � � � � � � � Ï Ù ì ¹ Æ Å Ç Å È Ä í ¾ » Â î » Á Á Â È Á Â Å » Ã ¹ Ô È Ú è ¹ Ç é ï

ð 1 � � ³ ° � � � ° � ° · � ¶ � ñ ° � � 6 ò ï Ï Ä Õ Â ¹ » Ç ¹ ò ë » Â Ò ó ï À ¹ Õ Â ¹ » Ç ¹ ò ë » Â Ò Ì ï Ï Ä Õ Â ¹ » Ç ¹ À Ó Â » Ã Å È Ä À ï À ¹ Õ Â ¹ » Ç ¹ À Ó Â » Ã Å È ÄÛ ï ç Ã Ö ¹ Â è Ç Á ¹ Õ Å Ù Í é ¿® ô 1 � � � � ¶ � ñ � � � ° � ° · � ¶ � � ³ ° � � � � � � � � � ° � ± ³ ² ° · Ï Ç Ã Ö Å Ç » Á Á ¼ Å Õ » Ã Å È Ä Ô ¹ Å Ä º Ç Ó Ô ¾ Å Ã Ã ¹ Ò Ã È È Ã Ö ¹ Â » º ¹ Ä Õ Å ¹ Ç õ ö Ï ö ¸ Û ¿® ® 1 � ° � · � ¯ � � ÷ ° � � � ¶ ° � � � ¯ ¯ ¶ � � � � � ø ¯ · � ù ° � �

ú 1 � � � ° ± ² ³ � � � ° �û 1 � � � ° · ° � ° � ÷ ° � ² 6 � � � °ü ý ý þ ÿ � ü � ÿ � � � � � � � � � � ü þ ü � � ÿ � � ü � � �

Ì È Ó Ä Ã Í Ñ Ð » Â Å Ç Ö ¿ Ð Â È Æ Å Ä Õ ¹ ¿Ð Â ¹ Ù Å Ú ¿

ê Ö » Ã È Ã Ö ¹ Â ò º ¹ Ä Õ Å ¹ Ç õ

Ð Â ¹ » Á Á ¼ Å Õ » Ã Å È Ä ò Á Á ¼ Å Õ » Ã Å È Ä Ì Ö » Ä º ¹ Ò Ñ Ì È Â Â ¹ Õ Ã ¹ Ò ò Á Á ¼ Å Õ » Ã Å È Ä

½ ¹ ë ì ¹ Ç Ó Ô ¾ Å Ç Ç Å È Äì ¹ Ä ¹ ë » ¼ Ì È Ä Ã Å Ä Ó » Ã Å È Ä ì ¹ Æ Å Ç Å È Ä ¹ Ç ½ È� 1 � 6 ¯ ° � � � ¯ ¯ ¶ � � � � � � �

ç Ø ó ½ Ó ¾ Ô ¹ Â ¿ � � Ê� 1 � � � � � � · � � � � � � 0 � � � � � � �

® ú 1 ¯ · � ¯ � ° � ¯ · � ù ° � � É Ã » Â Ã À » Ã ¹ Û Ä Ò Å Ä º À » Ã ¹ ® û 1 � � � ñ · ° � � � � ¶ � � � · � � � � � � ¯ ¯ ¶ � � � � �

� 1 ¯ � m � � � ñ � � � � 1 � m� � � 4 � � � � �

Ì È Ó Ä Ã Â Í ¿Ð È Ç Å Ã Å È Ä Ñ ö Å Ã ¼ ¹ ¿

Ð Â È Æ Å Ä Õ ¹ ¿Ì È Ó Ä Ã Í Ñ Ð » Â Å Ç Ö ¿É Ã » Ã ¹ ¿Ì Å Ã Í ¿É Ã Â ¹ ¹ Ã Ë ¿É Ã Â ¹ ¹ Ã Ê ¿ Î Ï Ð Ñ Ð È Ç Ã » ¼ Ì È Ò ¹ ¿� V O f � H K e d ` V e O e d V

� V O f � H K e d ` V e O e d V> J 8 : 9 8 9 8 J 8 < A ? C 8 ? M A = 8 M ? J J ? � I C i

H : A I ? C : J K C 9 A I A L A 8 9 ? M N 8 : J A =


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Do not use Pre-application unless specifically noted in FOA.

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Use Application for first submission attempt for due date.

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Use Changed/Corrected when correcting eRA identified errors/warnings.

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If New (box 8), leave blank unless otherwise instructed in FOA. If Resubmission, Renewal or Revision (box 8), use institute and serial # of previous NIH grant/application # (e.g., use CA987654 from 1R01CA987654-01).

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If Changed/Corrected (box 1), provide previous Grants.gov tracking #. (e.g., GRANT12345678).

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Must match DUNS used for System for Award Management (SAM), Grants.gov and eRA Commons registrations. Must be 9 or 13 digits; no letters or special characters.

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Must provide zip+4 for all zip codes.

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Contact e-mail is required by NIH. If not included, or improperly formatted, the AOR e-mail provided in item 19 will be used.

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See Application Guide for definitions.

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NIH will assign CFDA post-submission.

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Up to 200 characters.

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Start date is an estimate; typically at least nine months after submission. Project period should not exceed what is allowed in announcement.

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Format: 2 character state abbreviation - 3 character District number (e.g., CA-005. Use 00-000 if outside the US. See Application Guide for additional details.

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ASSIST - For Overall component, the Applicant information address fields are populated from the Commons institution Profile and are not editable.

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All SF424 R&R fields are collected in Overall Component. Only fields 5,7 (optional), 11 and 12 collected in other components.

ü ý ý þ ÿ � ü � ÿ � � � � � � � � � � ü þ ü � � ÿ � � ü � � �

® µ 1 ° � � ³ � � ° � ¯ · � ù ° � � � ± � � � � ñ» ï ö È Ã » ¼ × ¹ Ò ¹ Â » ¼ × Ó Ä Ò Ç ì ¹ � Ó ¹ Ç Ã ¹ Ò® æ 1 ² � � � � � � � � � / � � � � � � � � � � � � 3 � � � � � � � � ® � � � / � � � � � � � � � � � � � � � � � � 0 � � � / � � � � � � � � � � � � � � � � � � � � � 0 � ú � � / � � � / � � � � � � � � � � � / � � � � � �� 3 � � � � � � � � � 0 � � � � � � � � � / � � � � � � � � 4 � 2 � � 0 � � 1 � � � � � m � 0 � � / � � � � � � 0 � � � � � � � � � � � � 0 � � � � � � � � � � 2 � � / � � � � � � � � � � �� 2 � 0 1 � � � � 2 � � � / � � � � � � � � � � 3 � � � � � � � � � 1 � � � 0 � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � 3 � � m � � 3 � 0 � � � � � � � � � m � � � � � � � � � � 1 � ± 1 1 � 0 � 3 � � � � � ® � 3 � � � � � ® ô ô ® �® ð 1 � � � / � l � 0 · � � � � � � � � � � m �× Å Â Ç Ã ½ » ¾ ¹ ¿ Ø Å Ò Ò ¼ ¹ ½ » ¾ ¹ ¿¸ » Ç Ã ½ » ¾ ¹ ¿ É Ó Ù Ù Å Ú ¿Ð È Ç Å Ã Å È Ä Ñ ö Å Ã ¼ ¹ ¿ç Â º » Ä Å � » Ã Å È Ä ¿À ¹ Á » Â Ã ¾ ¹ Ä Ã ¿ À Å Æ Å Ç Å È Ä ¿É Ã Â ¹ ¹ Ã Ê ¿É Ã Â ¹ ¹ Ã Ë ¿Ì Å Ã Í ¿É Ã » Ã ¹ ¿ Î Ï Ð Ñ Ð È Ç Ã » ¼ Ì È Ò ¹ ¿Ì È Ó Ä Ã Â Í ¿Ð Ö È Ä ¹ ½ Ó ¾ Ô ¹ Â ¿ × » Ú ½ Ó ¾ Ô ¹ Â ¿Û ¾ » Å ¼ ¿ � � � � � � � � � � � / � l � 0 · � � � � � � � � � � m � � � � � � � � � 0ú ô 1 ¯ � � � � � � � � � � � �

� � � � � � � � ! " � # � � ! � " $ � � % � $ % & $ � � ' # $ % " � � ( # $ % ) % � � # % � � � � � � * � � # � + ' , $ + - � $ � % � � � � � � � � ( � � " % � $ � % � & � % � � � $ % % ' % " � , � % � # $ . � % " + � / � " � ! � " � % � � # ' " � � % � 0

Ì È Ó Ä Ã Í Ñ Ð » Â Å Ç Ö ¿

Õ ï ö È Ã » ¼ × ¹ Ò ¹ Â » ¼ 1 ½ È Ä × ¹ Ò ¹ Â » ¼ × Ó Ä Ò Ç® � 1 � ¶ ¶ ¶ � � � � � � � � � � ¶ � � � � � � � � � � m � � � � � � � / � ° 2 � � � � � � � � � � � � � � � � � �

Ð Â È Æ Å Ä Õ ¹ ¿

Ô ï ö È Ã » ¼ ½ È Ä × ¹ Ò ¹ Â » ¼ × Ó Ä Ò Ç

Ð Â ¹ Ù Å Ú ¿

× Å Â Ç Ã ½ » ¾ ¹ ¿ Ø Å Ò Ò ¼ ¹ ½ » ¾ ¹ ¿¸ » Ç Ã ½ » ¾ ¹ ¿ É Ó Ù Ù Å Ú ¿Ð È Ç Å Ã Å È Ä Ñ ö Å Ã ¼ ¹ ¿ç Â º » Ä Å � » Ã Å È Ä ½ » ¾ ¹ ¿À ¹ Á » Â Ã ¾ ¹ Ä Ã ¿ À Å Æ Å Ç Å È Ä ¿É Ã Â ¹ ¹ Ã Ê ¿É Ã Â ¹ ¹ Ã Ë ¿Ì Å Ã Í ¿ Î Ï Ð Ñ Ð È Ç Ã » ¼ Ì È Ò ¹ ¿Ì È Ó Ä Ã Â Í ¿Ð Ö È Ä ¹ ½ Ó ¾ Ô ¹ Â ¿ × » Ú ½ Ó ¾ Ô ¹ Â ¿Û ¾ » Å ¼ ¿É Ã » Ã ¹ ¿ Ì È Ó Ä Ã Í Ñ Ð » Â Å Ç Ö ¿ Ð Â È Æ Å Ä Õ ¹ ¿Ð Â ¹ Ù Å Ú ¿

® Ü 1 � � ¯ ¯ ¶ � � � � � � � ± ² ù ° � � � � · ° ÷ � ° 3 ² 6 � � � ° ° 4 ° � ± � � ÷ ° � · � ° ·® ú û æ ú ¯ · � � ° 5� � � � �

À ò ö Û ¿ö 6 Ï É Ð ì Û ò Ð Ð ¸ Ï Ì ò ö Ï ç ½ Ñ ò Ð Ð ¸ Ï Ì ò ö Ï ç ½ ê ò É Ø ò À Ûò 7 ò Ï ¸ ò ó ¸ Û ö ç ö 6 Û É ö ò ö Û Û 8 Û Ì 9 ö Ï 7 Û ç ì À Û ì Ê Ë : ; ËÐ ì ç Ì Û É É × ç ì ì Û 7 Ï Û ê ç ½ ¿Ð ì ç < ì ò Ø 6 ò É ½ ç ö ó Û Û ½ É Û ¸ Û Ì ö Û À ó É ö ò ö Û × ç ìì Û 7 Ï Û êÐ ì ç < ì ò Ø Ï É ½ ç ö Ì ç 7 Û ì Û À ó Û ï ç ï Ê Ë : ; Ë = ç ìÒ ï Û Ç Ã Å ¾ » Ã ¹ Ò Ð Â È º Â » ¾ Ï Ä Õ È ¾ ¹

ú ® 1 � m � ¶ � � � � � � � � � / � � � �

® ´ 1 ¯ · � ù ° � � � � · ° � � � · > ¯ · � � � � ¯ � ¶ � � ÷ ° � � ñ � � � · � � � � � � � � � � � · ³ � � � � �

� V O f � H K e d ` V e O e d V» ï Û ÉÔ ï ½ ç

� V O f � H K e d ` V e O e d V7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä ÃÀ ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã

ò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ã

W ? ^ _ J 8 A 8 b ? C 9 L ? ^ I 9 9 I ? C A ? B ; : C A 9 h i ? j W ? ^ _ J 8 A 8 b ? C 9 L ? ^ I 9 9 I ? C A ? B ; : C A 9 h i ? j7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä ÃÀ ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã FORMS-C Series (Footer not part of forms) Updated: March 25, 2015

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PD/PI first/last name should match name on file for Commons ID provided in the Credential field of the R&R Senior/Key Person Profile (Expanded) form.

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Manually enter estimated project funding amounts.

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See Supplemental Grant Application Instructions for full list of NIH policies and certifications. http://grants.nih.gov/grants/funding/424/index.htm

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Authorized Organization Representative (AOR) in Grants.gov must have signature authority for the organization. The electronic signature of the submitting AOR is recorded with submission. In eRA Commons this individual is called a Signing Official (SO).

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Cover Letter will be posted as a separate document in eRA Commons and is not part of the assembled application image. Content is only made available to select agency staff. See Application Guide for suggested cover letter format.

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ASSIST - For Overall component, the PD/PI information is pulled from the PD/PI section of the R&R Sr/Key Person Profile form and must be changed on that form.

c d ] ! Z � � � e , ! � � � ! f ] ! , ( � , % ' � - ( g � # � , h ' � ! ` ] e f ] - bÐ Â ¹ Ù Å Ú ¿B × Å Â Ç Ã ½ » ¾ ¹ ¿Ø Å Ò Ò ¼ ¹ ½ » ¾ ¹ ¿B ¸ » Ç Ã ½ » ¾ ¹ ¿É Ó Ù Ù Å Ú ¿i d X . " ' ( � . Y Z � � � #Ì ¼ Å Ä Å Õ » ¼ ö Â Å » ¼ õB ò º ¹ Ä Õ Í À ¹ Ù Å Ä ¹ Ò Ð Ö » Ç ¹ Ï Ï Ï Ì ¼ Å Ä Å Õ » ¼ ö Â Å » ¼ õ

ç Ø ó ½ Ó ¾ Ô ¹ Â ¿ @ Ë A Ê

½ È ¹ Ç½ È ¹ Ç½ È ¹ Ç

j d k e , # � � # . ! � ] � ! " , # # , ( � � ' � � " � ( �Ï Ù Ã Ö Å Ç » Á Á ¼ Å Õ » Ã Å È Ä Ò È ¹ Ç Ä È Ã Â ¹ Ç Ó ¼ Ã Å Ä » Ä » ë » Â Ò í Å Ç Ã Ö ¹ < È Æ ¹ Â Ä ¾ ¹ Ä Ã Á ¹ Â ¾ Å Ã Ã ¹ Ò Ã È Ò Å Ç Õ ¼ È Ç ¹ Ã Ö ¹ Ã Å Ã ¼ ¹ È Ù Í È Ó Â Á Â È Á È Ç ¹ Ò Á Â È C ¹ Õ Ã í » Ä Ò Ã Ö ¹ Ä » ¾ ¹ í» Ò Ò Â ¹ Ç Ç í Ã ¹ ¼ ¹ Á Ö È Ä ¹ Ä Ó ¾ Ô ¹ Â » Ä Ò ¹ ¾ » Å ¼ » Ò Ò Â ¹ Ç Ç È Ù Ã Ö ¹ È Ù Ù Å Õ Å » ¼ Ç Å º Ä Å Ä º Ù È Â Ã Ö ¹ » Á Á ¼ Å Õ » Ä Ã È Â º » Ä Å � » Ã Å È Ä í Ã È È Â º » Ä Å � » Ã Å È Ä Ç Ã Ö » Ã ¾ » Í Ô ¹Å Ä Ã ¹ Â ¹ Ç Ã ¹ Ò Å Ä Õ È Ä Ã » Õ Ã Å Ä º Í È Ó Ù È Â Ù Ó Â Ã Ö ¹ Â Å Ä Ù È Â ¾ » Ã Å È Ä è ¹ ï º ï í Á È Ç Ç Å Ô ¼ ¹ Õ È ¼ ¼ » Ô È Â » Ã Å È Ä Ç í Å Ä Æ ¹ Ç Ã ¾ ¹ Ä Ã é õl d k ] ! h ! ' " - ( � " �Ï Ù Í È Ó Õ Ö ¹ Õ î ¹ Ò m Í ¹ Ç m » Ô È Æ ¹ è Å Ä Ò Å Õ » Ã Å Ä º Ã Ö » Ã Á Â È º Â » ¾ Å Ä Õ È ¾ ¹ Å Ç » Ä Ã Å Õ Å Á » Ã ¹ Ò é í Ã Ö ¹ Ä Ó Ç ¹ Ã Ö ¹ Ù È Â ¾ » Ã Ô ¹ ¼ È ë Ã È Â ¹ Ù ¼ ¹ Õ Ã Ã Ö ¹ » ¾ È Ó Ä Ã » Ä ÒÇ È Ó Â Õ ¹ è Ç é ï ç Ã Ö ¹ Â ë Å Ç ¹ í ¼ ¹ » Æ ¹ Ã Ö Å Ç Ç ¹ Õ Ã Å È Ä Ô ¼ » Ä î ïB Ï Ç Á Â È º Â » ¾ Å Ä Õ È ¾ ¹ » Ä Ã Å Õ Å Á » Ã ¹ Ò Ò Ó Â Å Ä º Ã Ö ¹ Á ¹ Â Å È Ò Ç Ù È Â ë Ö Å Õ Ö Ã Ö ¹ º Â » Ä Ã Ç Ó Á Á È Â Ã Å Ç Â ¹ � Ó ¹ Ç Ã ¹ Ò õ ¹ Ç ½ ÈB ò Ä Ã Å Õ Å Á » Ã ¹ Ò ò ¾ È Ó Ä Ã è n éB ó Ó Ò º ¹ Ã Ð ¹ Â Å È Ò B É È Ó Â Õ ¹ è Ç é


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Section is pre-populated from SF 424 (R&R) cover form.

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The number of program income budget periods must be less than or equal to the number of periods included in the budget form.

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If Human Subjects = Yes on Other Project Information form, then an answer to Clinical Trial question is required.

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If Clinical Trial = No on all components, then Clinical Trial must be No on the Overall component for New and Renewal applications.

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If Clinical Trial = Yes on any components, then Clinical Trial must be Yes on the Overall component.

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If Phase III Clinical Trial = Yes on any component, then Phase III Clinical Trial must be Yes on the Overall component.

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NIH can accept Program Information at the Overall level, the component level or both. If the FOA does not explicitly indicate how to provide this data, then applicants can choose how best to reflect the information for their circumstances.

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If Phase III Clinical Trial = No on all components, then Phase III Clinical Trial must be No on the Overall component for New and Renewal applications.

o d X . " ' ( p " Y ! * ( , � � � � " $ � � � #B À È ¹ Ç Ã Ö ¹ Á Â È Á È Ç ¹ Ò Á Â È C ¹ Õ Ã Å Ä Æ È ¼ Æ ¹ Ö Ó ¾ » Ä ¹ ¾ Ô Â Í È Ä Å Õ Ç Ã ¹ ¾ Õ ¹ ¼ ¼ Ç õÏ Ù Ã Ö ¹ Á Â È Á È Ç ¹ Ò Á Â È C ¹ Õ Ã Å Ä Æ È ¼ Æ ¹ Ç Ö Ó ¾ » Ä ¹ ¾ Ô Â Í È Ä Å Õ Ç Ã ¹ ¾ Õ ¹ ¼ ¼ Ç í ¼ Å Ç Ã Ô ¹ ¼ È ë Ã Ö ¹ Â ¹ º Å Ç Ã Â » Ã Å È Ä Ä Ó ¾ Ô ¹ Â È Ù Ã Ö ¹ Ç Á ¹ Õ Å Ù Å Õ Õ ¹ ¼ ¼ ¼ Å Ä ¹ è Ç é Ù Â È ¾ Ã Ö ¹ Ù È ¼ ¼ È ë Å Ä º ¼ Å Ç Ã ¿Ö Ã Ã Á ¿ Ñ Ñ Ç Ã ¹ ¾ Õ ¹ ¼ ¼ Ç ï Ä Å Ö ï º È Æ Ñ Â ¹ Ç ¹ » Â Õ Ö Ñ Â ¹ º Å Ç Ã Â Í Ñ ï ç Â í Å Ù » Ç Á ¹ Õ Å Ù Å Õ Ç Ã ¹ ¾ Õ ¹ ¼ ¼ ¼ Å Ä ¹ Õ » Ä Ä È Ã Ô ¹ Â ¹ Ù ¹ Â ¹ Ä Õ ¹ Ò » Ã Ã Ö Å Ç Ã Å ¾ ¹ í Á ¼ ¹ » Ç ¹ Õ Ö ¹ Õ î Ã Ö ¹ Ô È Ú Å Ä Ò Å Õ » Ã Å Ä º Ã Ö » ÃÈ Ä ¹ Ù Â È ¾ Ã Ö ¹ Â ¹ º Å Ç Ã Â Í ë Å ¼ ¼ Ô ¹ Ó Ç ¹ Ò ¿É Á ¹ Õ Å Ù Å Õ Ç Ã ¹ ¾ Õ ¹ ¼ ¼ ¼ Å Ä ¹ Õ » Ä Ä È Ã Ô ¹ Â ¹ Ù ¹ Â ¹ Ä Õ ¹ Ò » Ã Ã Ö Å Ç Ã Å ¾ ¹ ï ç Ä ¹ Ù Â È ¾ Ã Ö ¹ Â ¹ º Å Ç Ã Â Í ë Å ¼ ¼ Ô ¹ Ó Ç ¹ Ò ï$ � � � q , ( � ` # b r ¹ Ç½ È

s d - ( g � ( � , ( # ' ( ) ] ' � � ( � # ` � ! ! � ( � t ' � ' % % � , � ' � , ( # ( � * bB Ï Ä Æ ¹ Ä Ã Å È Ä Ç » Ä Ò Ð » Ã ¹ Ä Ã Ç ¿Ï Ù Ã Ö ¹ » Ä Ç ë ¹ Â Å Ç m ¹ Ç m Ã Ö ¹ Ä Á ¼ ¹ » Ç ¹ » Ä Ç ë ¹ Â Ã Ö ¹ Ù È ¼ ¼ È ë Å Ä º ¿B Ð Â ¹ Æ Å È Ó Ç ¼ Í ì ¹ Á È Â Ã ¹ Ò ¿ ½ È ¹ Ç ¹ Ç ½ Èu d $ [ ' ( h � a - ( g � # � , h ' � ! f $ [ ' ( h � a - ( # � , � . � , ( v . � # � , ( #Ì Ö » Ä º ¹ È Ù Á Â Å Ä Õ Å Á » ¼ Å Ä Æ ¹ Ç Ã Å º » Ã È Â Ñ Á Â È º Â » ¾ Ò Å Â ¹ Õ Ã È Â½ » ¾ ¹ È Ù Ù È Â ¾ ¹ Â Á Â Å Ä Õ Å Á » ¼ Å Ä Æ ¹ Ç Ã Å º » Ã È Â Ñ Á Â È º Â » ¾ Ò Å Â ¹ Õ Ã È Â ¿Ì Ö » Ä º ¹ È Ù < Â » Ä Ã ¹ ¹ Ï Ä Ç Ã Å Ã Ó Ã Å È ÄB ½ » ¾ ¹ È Ù Ù È Â ¾ ¹ Â Å Ä Ç Ã Å Ã Ó Ã Å È Ä ¿

Ð Â ¹ Ù Å Ú ¿B × Å Â Ç Ã ½ » ¾ ¹ ¿Ø Å Ò Ò ¼ ¹ ½ » ¾ ¹ ¿B ¸ » Ç Ã ½ » ¾ ¹ ¿É Ó Ù Ù Å Ú ¿ FORMS-C Series (Footer not part of forms) Updated: March 25, 2015

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If Yes, then approved cell line entries must be entered or the "cannot be referenced" box must be checked. If Yes on any component, then must be Yes on Overall component.

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Error if provided human embryonic stem cell lines (e.g., 0024, 0139) are not listed at http://stemcells.nih.gov/research/registry/ at time of submission. Overall component must include any stem cell lines listed in other components.

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Cross-Out

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Only check 'cell line cannot be referenced' if no cell lines are referenced on any component. Note: Future enhancement planned to allow entry of cell lines and ability to check this box for the Overall component.

Ê ï ò Â ¹ 6 Ó ¾ » Ä É Ó Ô C ¹ Õ Ã Ç Ï Ä Æ È ¼ Æ ¹ Ò õÏ ì ó ò Á Á Â È Æ » ¼ À » Ã ¹ ¿6 Ó ¾ » Ä É Ó Ô C ¹ Õ Ã ò Ç Ç Ó Â » Ä Õ ¹ ½ Ó ¾ Ô ¹ Â ¿Ë ï ò Â ¹ 7 ¹ Â Ã ¹ Ô Â » Ã ¹ ò Ä Å ¾ » ¼ Ç 9 Ç ¹ Ò õÏ ò Ì 9 Ì ò Á Á Â È Æ » ¼ À » Ã ¹ ¿ò Ä Å ¾ » ¼ ê ¹ ¼ Ù » Â ¹ ò Ç Ç Ó Â » Ä Õ ¹ ½ Ó ¾ Ô ¹ Â ¿� ï Ô ï Ï Ù Í ¹ Ç í Á ¼ ¹ » Ç ¹ ¹ Ú Á ¼ » Å Ä ¿� ï Õ ï Ï Ù Ã Ö Å Ç Á Â È C ¹ Õ Ã Ö » Ç » Ä » Õ Ã Ó » ¼ È Â Á È Ã ¹ Ä Ã Å » ¼ Å ¾ Á » Õ Ã È Ä Ã Ö ¹ ¹ Ä Æ Å Â È Ä ¾ ¹ Ä Ã í Ö » Ç » Ä ¹ Ú ¹ ¾ Á Ã Å È Ä Ô ¹ ¹ Ä » Ó Ã Ö È Â Å � ¹ Ò È Â » Ä ¹ Ä Æ Å Â È Ä ¾ ¹ Ä Ã » ¼ » Ç Ç ¹ Ç Ç ¾ ¹ Ä Ã è Û ò é È Â¹ Ä Æ Å Â È Ä ¾ ¹ Ä Ã » ¼ Å ¾ Á » Õ Ã Ç Ã » Ã ¹ ¾ ¹ Ä Ã è Û Ï É é Ô ¹ ¹ Ä Á ¹ Â Ù È Â ¾ ¹ Ò õ� ï Ò ï Ï Ù Í ¹ Ç í Á ¼ ¹ » Ç ¹ ¹ Ú Á ¼ » Å Ä ¿D ï À È ¹ Ç Ã Ö Å Ç Á Â È C ¹ Õ Ã Å Ä Æ È ¼ Æ ¹ » Õ Ã Å Æ Å Ã Å ¹ Ç È Ó Ã Ç Å Ò ¹ È Ù Ã Ö ¹ 9 Ä Å Ã ¹ Ò É Ã » Ã ¹ Ç È Â Á » Â Ã Ä ¹ Â Ç Ö Å Á Ç ë Å Ã Ö Å Ä Ã ¹ Â Ä » Ã Å È Ä » ¼ Õ È ¼ ¼ » Ô È Â » Ã È Â Ç õD ï Ô ï ç Á Ã Å È Ä » ¼ Û Ú Á ¼ » Ä » Ã Å È Ä ¿æ 1 ¯ � � � � � � � � � > � � � � � � �

® ® 1 ° � � � � � � � �� 1 ¯ � � � � � � � � � m �® ú 1 � � / � � � � � � / � � � � �

| } ~ } � | � � � | } � � � } � � � � � � � � � � � � � � � � � � � � � � � �

Ï Ç Ã Ö ¹ Ï ò Ì 9 Ì Â ¹ Æ Å ¹ ë Ð ¹ Ä Ò Å Ä º õÏ Ù Ä È í Å Ç Ã Ö ¹ Ï ì ó Â ¹ Æ Å ¹ ë Ð ¹ Ä Ò Å Ä º õ

Ë ï » ï Ï Ù Û É Ã È 7 ¹ Â Ã ¹ Ô Â » Ã ¹ ò Ä Å ¾ » ¼ Ç: ï Ï Ç Á Â È Á Â Å ¹ Ã » Â Í Ñ Á Â Å Æ Å ¼ ¹ º ¹ Ò Å Ä Ù È Â ¾ » Ã Å È Ä Å Ä Õ ¼ Ó Ò ¹ Ò Å Ä Ã Ö ¹ » Á Á ¼ Å Õ » Ã Å È Ä õ� ï » ï À È ¹ Ç Ã Ö Å Ç Ð Â È C ¹ Õ Ã 6 » Æ ¹ » Ä ò Õ Ã Ó » ¼ È Â Ð È Ã ¹ Ä Ã Å » ¼ Ï ¾ Á » Õ Ã Á È Ç Å Ã Å Æ ¹ È Â Ä ¹ º » Ã Å Æ ¹ È Ä Ã Ö ¹ ¹ Ä Æ Å Â È Ä ¾ ¹ Ä Ã õD ï » ï Ï Ù Í ¹ Ç í Å Ò ¹ Ä Ã Å Ù Í Õ È Ó Ä Ã Â Å ¹ Ç ¿

ð 1 ² � � � � � � � / � w · � � � � � � � � � � � � 0® ô 1 � � � � � � � � � � w � � / � · � � � � � �

¹ Ç ½ ÈÊ ï » ï Ï Ù Û É Ã È 6 Ó ¾ » Ä É Ó Ô C ¹ Õ Ã Ç ¹ Ç ½ È ¹ Ç ½ ÈÏ Ù Í ¹ Ç í Õ Ö ¹ Õ î » Á Á Â È Á Â Å » Ã ¹ ¹ Ú ¹ ¾ Á Ã Å È Ä Ä Ó ¾ Ô ¹ Â ï ¹ Ç ½ È ¹ Ç ½ È ¹ Ç ½ È ¹ Ç ½ È ¹ Ç ½ È

¹ Ç ½ È

Ï Ç Ã Ö ¹ Ð Â È C ¹ Õ Ã Û Ú ¹ ¾ Á Ã Ù Â È ¾ × ¹ Ò ¹ Â » ¼ Â ¹ º Ó ¼ » Ã Å È Ä Ç õ

A ï Ï Ç Ã Ö ¹ Â ¹ Ç ¹ » Â Õ Ö Á ¹ Â Ù È Â ¾ » Ä Õ ¹ Ç Å Ã ¹ Ò ¹ Ç Å º Ä » Ã ¹ Ò í È Â ¹ ¼ Å º Å Ô ¼ ¹ Ã È Ô ¹ Ò ¹ Ç Å º Ä » Ã ¹ Ò í » Ç » Ö Å Ç Ã È Â Å Õ Á ¼ » Õ ¹ õ ¹ Ç ½ ÈA ï » ï Ï Ù Í ¹ Ç í Á ¼ ¹ » Ç ¹ ¹ Ú Á ¼ » Å Ä ¿

ç Ø ó ½ Ó ¾ Ô ¹ Â ¿ � � ÊÊ Ë : � A D

7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä ÃÀ ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä ÃÀ ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä ÃÀ ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä ÃÀ ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä ÃÀ ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ã ÇÀ ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Çò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ç


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If Human Subjects = Yes, additional attachments are required in the PHS 398 Research Plan or equivalent form. If Yes on any component, then must be Yes on Overall component.

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Overall: Future date not allowed. Date is not required at time of submission, but may be requested later as Just-In-Time data. Other components: not collected.

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Overall: If Human Subjects = Yes, then Human Subject Assurance Number or the text 'None' must be provided. Other components: not collected.

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If Vertebrate Animals = Yes, additional attachments are required in the PHS 398 Research Plan form. If Yes on any component, then must be Yes on Overall component.

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Overall: Future date not allowed. Date is not required at time of submission, but may be requested later as Just-In-Time data. Other components: not collected.

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Overall: If Vertebrate Animals = Yes, then Animal Welfare Assurance Number or the text 'None' must be provided. Other components: not collected.

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Typically 2-3 sentence statement of public health relevance; system will give error if over 1 page. Overall: Required. Other components: optional - see FOA for instructions.

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Only provide Other Attachments when requested in the FOA.

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If Overall exemption number is 4, then no other exemption number can be set for any other component.

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If 4a is Yes, then 4b is required.

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If 4c is Yes, then 4d is required.

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If 5 is Yes, then 5a is required.

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If 6 is Yes, then 6a is required.

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If Yes on any component, then must be Yes on Overall component.

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User-defined bookmarks provided with this attachment will be included with the bookmarks for the assembled application image in eRA Commons.

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User-defined bookmarks provided with this attachment will be included with the bookmarks for the assembled application image in eRA Commons.

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Succinct project summary of proposed work. Typically 30 lines or less; system error if over 1 page. If awarded this information becomes public. Do not include proprietary or confidential information.

� � � � � � � � � � � � � � � � � � � ~ � � � � � � � � � � � � � � ç Ø ó ½ Ó ¾ Ô ¹ Â ¿ � � Ê ¯ � � � � > ¯ � � � � � � � � � � ¯ � � � � ¶ � � � � � Ï » ¾ Ç Ó Ô ¾ Å Ã Ã Å Ä º » Ä » Á Á ¼ Å Õ » Ã Å È Ä » Ç » Ä Å Ä Ò Å Æ Å Ò Ó » ¼ í » Ä Ò Ä È Ã È Ä Ô ¹ Ö » ¼ Ù È Ù » Õ È ¾ Á » Ä Í í Ç Ã » Ã ¹ í¼ È Õ » ¼ È Â Ã Â Å Ô » ¼ º È Æ ¹ Â Ä ¾ ¹ Ä Ã í » Õ » Ò ¹ ¾ Å » í È Â È Ã Ö ¹ Â Ã Í Á ¹ È Ù È Â º » Ä Å � » Ã Å È Ä ïç Â º » Ä Å � » Ã Å È Ä ½ » ¾ ¹ ¿À 9 ½ É ½ Ó ¾ Ô ¹ Â ¿B É Ã Â ¹ ¹ Ã Ê ¿É Ã Â ¹ ¹ Ã Ë ¿B Ì Å Ã Í ¿ Ì È Ó Ä Ã Í ¿B É Ã » Ã ¹ ¿Ð Â È Æ Å Ä Õ ¹ ¿B Ì È Ó Ä Ã Â Í ¿B Î Ï Ð Ñ Ð È Ç Ã » ¼ Ì È Ò ¹ ¿ B Ð Â È C ¹ Õ Ã Ñ Ð ¹ Â Ù È Â ¾ » Ä Õ ¹ É Å Ã ¹ Ì È Ä º Â ¹ Ç Ç Å È Ä » ¼ À Å Ç Ã Â Å Õ Ã ¿¯ � � � � > ¯ � � � � � � � � � � ¶ � � � � � Ï » ¾ Ç Ó Ô ¾ Å Ã Ã Å Ä º » Ä » Á Á ¼ Å Õ » Ã Å È Ä » Ç » Ä Å Ä Ò Å Æ Å Ò Ó » ¼ í » Ä Ò Ä È Ã È Ä Ô ¹ Ö » ¼ Ù È Ù » Õ È ¾ Á » Ä Í í Ç Ã » Ã ¹ í¼ È Õ » ¼ È Â Ã Â Å Ô » ¼ º È Æ ¹ Â Ä ¾ ¹ Ä Ã í » Õ » Ò ¹ ¾ Å » í È Â È Ã Ö ¹ Â Ã Í Á ¹ È Ù È Â º » Ä Å � » Ã Å È Ä ïç Â º » Ä Å � » Ã Å È Ä ½ » ¾ ¹ ¿À 9 ½ É ½ Ó ¾ Ô ¹ Â ¿B É Ã Â ¹ ¹ Ã Ê ¿É Ã Â ¹ ¹ Ã Ë ¿B Ì Å Ã Í ¿ Ì È Ó Ä Ã Í ¿B É Ã » Ã ¹ ¿Ð Â È Æ Å Ä Õ ¹ ¿B Ì È Ó Ä Ã Â Í ¿B Î Ï Ð Ñ Ð È Ç Ã » ¼ Ì È Ò ¹ ¿ B Ð Â È C ¹ Õ Ã Ñ Ð ¹ Â Ù È Â ¾ » Ä Õ ¹ É Å Ã ¹ Ì È Ä º Â ¹ Ç Ç Å È Ä » ¼ À Å Ç Ã Â Å Õ Ã ¿� 0 0 � � � � � � ¶ � � � � � � � �

� � � � � � � � ¡ � � � � �Ê

� � � � � � � � ¡ � � � � �ò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ã


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DO NOT check box. NIH only accepts applications from registered organizations.

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DUNS required and enforced by NIH. Must be 9 or 13 digits; no letters or special characters.

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Can collect data for 300 locations (including primary site) prior to using Additional Location(s) attachment.

Ð Â È Æ Å Ä Õ ¹ ¿¯ · � � � ¶ ° � ¯ � � � � � � � � � > ¯ � � � � � � � � � m � � � � � � � Ð Â ¹ Ù Å Ú ¿ B × Å Â Ç Ã ½ » ¾ ¹ ¿ Ø Å Ò Ò ¼ ¹ ½ » ¾ ¹ ¿B ¸ » Ç Ã ½ » ¾ ¹ ¿ É Ó Ù Ù Å Ú ¿ç Â º » Ä Å � » Ã Å È Ä ½ » ¾ ¹ ¿ À Å Æ Å Ç Å È Ä ¿Ð È Ç Å Ã Å È Ä Ñ ö Å Ã ¼ ¹ ¿ À ¹ Á » Â Ã ¾ ¹ Ä Ã ¿B É Ã Â ¹ ¹ Ã Ê ¿É Ã Â ¹ ¹ Ã Ë ¿

B Ð Ö È Ä ¹ ½ Ó ¾ Ô ¹ Â ¿ × » Ú ½ Ó ¾ Ô ¹ Â ¿B Û Ø » Å ¼ ¿Ì Â ¹ Ò ¹ Ä Ã Å » ¼ í ¹ ï º ï í » º ¹ Ä Õ Í ¼ È º Å Ä ¿� ¯ � � � � · � � � � / � ¯ � � � � · � � � � � � � � B Î Å Á Ñ Ð È Ç Ã » ¼ Ì È Ò ¹ ¿B Ì È Ó Ä Ã Â Í ¿B É Ã » Ã ¹ ¿ Ì È Ó Ä Ã Í Ñ Ð » Â Å Ç Ö ¿B Ì Å Ã Í ¿

� � � � � / � � � � � w ¯ � � 0 � � � � � � �� / ² � � � � / � � � � 4 � � � /

ç Ø ó ½ Ó ¾ Ô ¹ Â ¿ � � Ê

� � � � � � � � � � � � � � 6 � �

Ð Â È Æ Å Ä Õ ¹ ¿¯ · � � � ¶ ° � � � � > x � � ¯ � � �Ð Â ¹ Ù Å Ú ¿ B × Å Â Ç Ã ½ » ¾ ¹ ¿ Ø Å Ò Ò ¼ ¹ ½ » ¾ ¹ ¿B ¸ » Ç Ã ½ » ¾ ¹ ¿ É Ó Ù Ù Å Ú ¿ç Â º » Ä Å � » Ã Å È Ä ½ » ¾ ¹ ¿ À Å Æ Å Ç Å È Ä ¿Ð È Ç Å Ã Å È Ä Ñ ö Å Ã ¼ ¹ ¿ À ¹ Á » Â Ã ¾ ¹ Ä Ã ¿B É Ã Â ¹ ¹ Ã Ê ¿É Ã Â ¹ ¹ Ã Ë ¿

B Ð Ö È Ä ¹ ½ Ó ¾ Ô ¹ Â ¿ × » Ú ½ Ó ¾ Ô ¹ Â ¿B Û Ø » Å ¼ ¿Ì Â ¹ Ò ¹ Ä Ã Å » ¼ í ¹ ï º ï í » º ¹ Ä Õ Í ¼ È º Å Ä ¿ B Î Å Á Ñ Ð È Ç Ã » ¼ Ì È Ò ¹ ¿B Ì È Ó Ä Ã Â Í ¿B É Ã » Ã ¹ ¿ Ì È Ó Ä Ã Í Ñ Ð » Â Å Ç Ö ¿B Ì Å Ã Í ¿� ¯ � � � � · � � � � / � ¯ � � � � · � � � � � � � � � � � � � � � � � � � � � � 6 � � � � � � � / ² � � � � / � � � � 4 � � � /� � � � � / � � � � � w ¯ � � 0 � � � � � � �� { � | � ~ { � ~ � � { ~ � { ~ � � ~ � } � � { � � � � � | � � ~ � y } � � { ~ } � � � � � q � } � � � � � � � } � n { � � � ~ � � { � v { ~ | � � | y � � { } | { | } � { � � � ~ } � � � � � } � � � � z � � � | { � � { � � � � {s { } � { ~ z } � � ~ { � � { � � � {

� V O f � H K e d ` V e O e d V> ` Y > K 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä ÃÀ ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ã

� V O f � H K e d ` V e O e d V

À ¹ ¼ ¹ Ã ¹ Û Ä Ã Â Í ½ ¹ Ú Ã Ð ¹ Â Ç È Ä

®

ò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ã FORMS-C Series (Footer not part of forms) Updated: March 25, 2015

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Organization Name required by NIH.

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Valid eRA Commons username required by NIH. Overall: Contact PD/PI must be affiliated in Commons with applicant organization.

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Overall: Project Role must be PD/PI. Other components: Project Role can't be PD/PI.

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Each Sr/Key person is allowed one biosketch for the entire application. When participating on multiple components, chose any single entry to attach biosketch and make sure it reflects participation on each component. New format (NOT-OD-15-032) limited to 5 pages. Format and samples: http://grants.nih.gov/grants/funding/424/index.htm.

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Only provide Current & Pending Support if specifically requested in FOA. May be requested later in pre-award process as Just-In-Time data.

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Organization Name required by NIH for all Sr/Key entries. This information is used by NIH staff to determine potential review conflicts of interest.

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Overall: For multiple PD/PI applications, you must use the PD/PI role and provide the eRA Commons username in the Credential field for all PD/PIs. When multiple PD/PIs are included, the Multiple PD/PI Leadership Plan on the Research Plan form is required.

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Can collect data for 100 Sr/Key personnel (including PD/PI). Option to provide attachment for additional Sr./Key info is available after the 100 entries are made.

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ASSIST - PD/PI Organization Name is pre-populated from SF 424 (R&R) cover.

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ASSIST - For other components. Project Role defaults to Other with an Other Project Role Category of Project Lead.

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Each Sr/Key person is allowed one biosketch for the entire application. When participating on multiple components, chose any single entry to attach biosketch and make sure it reflects participation on each component. New format (NOT-OD-15-032) limited to 5 pages. Format and samples: http://grants.nih.gov/grants/funding/424/index.htm.

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Only provide Current & Pending Support if specifically requested in FOA. May be requested later in pre-award process as Just-In-Time data.

cd e � Rf g h ij � � j � k � l m � � j �n � � � �j h o �� p � � h ij e p � � hm � q r s t u r R t m s rv p w s o hJ 7 G x 69 C yz { : F : 7 = > | G ; @ G 7 C 8 z 5 } ~ � ��

�� " ) $ �� ) � " �� ¡¢ � � �� £ � � ¡ � � ¤ ¥ ¦ § � © � ª �« �¬ ® � ¬ ¡¢ ¬ ° � ±¢ � � � � �¡ � � ¤ ¥ ¦ § �� © ² �£ � © � � � � � ¥ ¦ § �¢ © � �° � ±¢ � � � � � ¥ ¦ §� � ³ � ® � °¨ � � � � � � � © � ¡ � © � � µ � ¤ � �� © � ¶¨ � � �¢ © � � � � ±¢ � � � � � � � � � ¡ � © � �µ � ¤ � �� © � � © � ª � � � ® ª � � � � � �¶¨ � � ¡ � © � � · µ � ¤ � �� ©¸ � ¹ & º � ) �� ) � " � �» ¢ ¼ �� © © � � � � ³ � ® � °¨ � � �¢ © � �° � ±¢ � � � � � ¥ ¦ §�� © ² �£ � © � � � � � ¥ ¦ §° � ±¢ � � � � �¡ � � ¤ ¥ ¦ §¡¢ ¬® � ¬« � ¬ � © � ª �J G @ C ½ G9 C G 7 : ? 4 @ @ G9 8 : C 6 @¾ 7 : = z : C 6 y Cz = 6 ; C @P ; = 6 7 ¿ 7 : = z : C 6 y Cz = 6 ; C @y 69 7 6 C : 7 8 : ? > | ? 6 7 89 : ?¶¨ � � » ¢ ¼ �� À � ª � � � � � � © © � � ¶¨ � � À � ª �� © © � �Á " & � � � � � � ) �Â Ã � Ä � � � * � ) � Ä � ¸ � � Å � & � Æ �Ç È

' É � É � ' Ê Ë Ì ' É Í � Á É Î � Î Ï É ÁÐ ¸Ñ * Ä � & �� ) � " * Òcd e � Ó � � � e h ÔÕ Ö Ö Õ × ×Ø Ù Ú � � Û × Ü� Ý � ×� Õ × × Ø Ù Ú � � Û × Þ ß � à Õ × × Ø Ù Ú � � Û ×


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Provide DUNS for the organization whose budget is reflected on this form.

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Use Project when providing data for the budget associated with the component's lead organization. DUNS is used to differentiate applicant and subaward budgets.

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Every Sr./Key listed must have measurable effort in either Calendar Months or a combination of Academic and Summer Months.

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Role should reflect the Sr/Key persons role on the specific component.

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PD/PI must be listed as a Sr/Key with measurable effort in every budget period.

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If more than 100 Sr./Key, use attachment and enter total funds requested for additional Sr/Key persons.

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Aggregate information should be provided in section B. More detailed information should be provided in Budget Justification.

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R&R Budget form will NOT be used in the Overall component. Instead, NIH will summarize budget information from other components and include the summaries in the assembled application in eRA Commons post submission.

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Budget summary information available in ASSIST pre-submission using the Preview Application action.

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For New and Resubmission applications, the first budget period start date must match the start date listed on the SF 424 (R&R) cover. Start/end dates must be within or equal to the project period dates on the SF 424 (R&R) cover.

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You can name up to 5 additional Project Role categories. Once data for the first user-defined Project Role is entered, you will have the option to add another.

Ê � Éá Ñ � ( � � & Î� � â ) � ( & � " v � � � � k � j e e � � � � � � k �d j � l � � � � ã � � k ä � e � j åæç è è èé ±¢ �ê � © � � � � �¢ © � � ° � ±¢ � � � � � ¥ ¦ §

¶¨ � � �¢ © � � � � ±¢ � � � � � � � � � � ±¢ �ê � © � � � � � � � � © � ª � � � ® ª � � � � � �¶¨ � � é ±¢ �ê � © � � � � � � © � é ±¢ � ê � © � ´Î � Á ) � ë� �½ G 5 6 @ C 89 ì 7 :D 6 ? | G @ C @ í < ;9 ?î | : ; : = :ï N 6 ð 89 G : ; = Pî yî J G @ @ 6 @ @ 8 G ; @ ñÔò ó G 7 6 8 ¿ ; ì 7 :D 6 ? | G @ C @ôò ¶¨ � � ¶� õ � � « � � �¢ © � � ° � ±¢ � � � � � ¥ ¦ §

É � � � ) & � â � ( � & $ Á ) � � � � �Ñ ( ( " ) & Ê " � & �ìz 8 C 8 G ; > ó 6 6 @ > E 6 : ? C I < ; @z 7 : ;9 6Ôò y C 8 Q 6 ; = @ôò ì 7 :D 6 ?öò yz { @ 8 @ C 6 ;9 6÷ò H C I 6 7æ ò

�¢ © � � ° � ±¢ � � � � � ¥ ¦ §

» ¢ ¼ �� ® �ê © � � · ¶� � © � � � ¶¨ � � � � � � ® �ê © � · ¶� � © � � ¡¢ ê ê � � « � � �Þ ß � à Õ × ×Ø Ù Ú � � Û ×Ü� Ý � ×� Õ × × Ø Ù Ú � � Û ×Õ Ö Ö Õ × × Ø Ù Ú � � Û ×


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Once equipment data is entered, you will be able to add up to 99 more rows to this section for a total of 100 equipment items.

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Only complete this section if requested to do so in the FOA.

� � ¹ & º � ) Î � )� â & Ê " � & � �¢ © � � ° � ±¢ � � � � � ¥ ¦ §Ôò N : C 6 7 8 : ? @ : ; = yz Q Q ? 8 6 @ôò Jz { ? 89 : C 8 G ; | G @ C @öò | G ; @z ? C : ; C y 6 7D 89 6 @÷ò 4 ½ J > | G 5 Qz C 6 7 y 6 7D 89 6 @æ ò yz { : F : 7 = @ > | G ; @ G 7 C 8z 5 > | G ; C 7 :9 Cz : ? | G @ C @øò ùú z 8 Q 5 6 ; C G 7 ó :9 8 ? 8 Cû O 6 ; C : ? > P @ 6 7 ó 6 6 @üò 4 ? C 6 7 : C 8 G ; @ : ; = O 6 ; GD : C 8 G ; @ýòþòÔ èò ¶¨ � � À � ª �� ÿ � � � ® � « � � �Ï � Î � )� â & Ê " � & � �¢ © � � ° � ±¢ � � � � � ¥ ¦ §Á " & � � Î � )� â & Ê " � & � Æ � & º )Ñ � ÈË � � * � )� â & Ê " � & �� © � � � � ® � « � � ¶ ¤ê � � © � � � � ® � « � � ° � � ¥ � § � © � � � � ® � « � � £ � � ¥ ¦ § �¢ © � � ° � ±¢ � � � � � ¥ ¦ §Á " & � � � * � )� â & Ê " � & �« ² © �� © � � � � �� ² � © ® ¤� �� Á " & � � Î � )� â & � * � * � )� â & Ê " � & � �¢ © � � ° � ±¢ � � � � � ¥ ¦ §Á " & � � Î � )� â & � * � * � )� â & � � & � &Ñ & � " � � Ê " � & � Æ Ï Ç Ë È� � �� ¢ © � � ° � ±¢ � � � � � ¥ ¦ §�� ¸ Ñ * Ä � & � Ñ � & � Å � â � & � " � } Û Ý� Ø × ×Ø Ù Ú� Û � � ß Ý �� Õ Ö Ö Õ × × Ø Ù Ú � � Û × Ü� Ý � ×� Õ × × Ø Ù Ú � � Û × Þ ß � à Õ × ×Ø Ù Ú � � Û ×


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Subaward/Consortium/Contractural Costs is not pre-populated. Include both Direct and Indirect costs.

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Budget justification is required and must cover all budget periods.

¡ � ® � � © ¡ � © � � · µ � ¤ � �� ©¡ � ® � � © « é ±¢ � ê � © �' É � É � ' Ê Ë Ì ' É Í � Á É Î � Î Ï É Á Ð Ê Ñ � Ñ � � & � ë� ¸Ñ * Ä � &

¡ � ® � � © ÿ ¶� õ � �Ü� � � ! × ß Ù¡ � ® � � © é � � � � ® �ê © � · ¶� � © � � ¡¢ ê ê � � « � � �"� �� ß# Û$� ß × ß� Û % "� � ! % & � Ø Ý × Ú ' Û !� �Ø Û Ù�( × ß) � Û Ö !$ �Ø *� Ý(� � ! ß ! ×� Û Ù�} × Ú � �� + Ø � × ß Ù ß) Ø Û × ! % $ �Ø ß Û � � !, ¬-¬.¬/¬0¬1¬

, ¬-¬¡ � ® � � © � À � ª �� ÿ � � � ® � « � � �~ Ø ×� � ß Ø Ý ! Ø Û Ö (� ) ) Ý ß � !, ¬ +� � Ý ß Ù Ø × ß� Û 2� ! × !-¬ 2� Û !� Ý × Ø Û × ( � � * ß Ù� !.¬ Õ Ü + % 2� �) � ×� � (� � * ß Ù� !/¬ (� � Ø àØ � Ö ! % 2� Û !� � × ß� � % 2� Û × �Ø Ù ×� Ø Ý 2� ! × !0¬ 34 � ß) � � Û ×� � " Ø Ù ß Ý ß ×� 5� Û × Ø Ý % 6 !� � "� � !1¬ Õ Ý ×� �Ø × ß� Û ! Ø Û Ö 5� Û� *Ø × ß� Û !7¬8¬9¬, :¬

¶¨ � � � ¥ ¦ §$� × Ø Ý �� } × Ú � � +� � !� Û Û � Ý¶¨ � � ¡ � � ¤ ; ² � � © � �� © ² � £ � © � � � � � ¥ < £ §} × Ú � � �} × Ú � � =} × Ú � � >

¡ � ® � � © £ À � ª �� © © � �¡ � ® � � © ? � � �¡ � ® � � © � ¶¨ � � ÿ � � � ® � © � � © � � � � ® � « � � � ¥ @ < A §¡ � ® � � © A � © � � � � ® � « � � �¡ � ® � � © @ ÿ � � � ® � « � � � ¥ � ª � ¢ � §


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Cumulative Budget is system generated based on budget period data provided.

Ï Ä Ç Ã Â Ó Õ Ã Å È Ä Ç ¿ ç Ä Ã Ö Å Ç Ù È Â ¾ í Í È Ó ë Å ¼ ¼ » Ã Ã » Õ Ö Ã Ö ¹ ì 1 ì É Ó Ô » ë » Â Ò ó Ó Ò º ¹ Ã Ù Å ¼ ¹ Ç Ù È Â Í È Ó Â º Â » Ä Ã » Á Á ¼ Å Õ » Ã Å È Ä ï Ì È ¾ Á ¼ ¹ Ã ¹ Ã Ö ¹ Ç Ó Ô » ë » Â Ò ¹ ¹ Ô Ó Ò º ¹ Ã è Ç é Å Ä» Õ Õ È Â Ò » Ä Õ ¹ ë Å Ã Ö Ã Ö ¹ ì 1 ì Ô Ó Ò º ¹ Ã Å Ä Ç Ã Â Ó Õ Ã Å È Ä Ç ï Ð ¼ ¹ » Ç ¹ Â ¹ ¾ ¹ ¾ Ô ¹ Â Ã Ö » Ã » Ä Í Ù Å ¼ ¹ Ç Í È Ó » Ã Ã » Õ Ö ¾ Ó Ç Ã Ô ¹ » Ð À × Ò È Õ Ó ¾ ¹ Ä Ã ïÏ ¾ Á È Â Ã » Ä Ã ¿ Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö Í È Ó Â Ç Ó Ô » ë » Â Ò ¹ ¹ Ô Ó Ò º ¹ Ã Ù Å ¼ ¹ è Ç é ë Å Ã Ö Ã Ö ¹ Ù Å ¼ ¹ Ä » ¾ ¹ È Ù Ã Ö ¹ Ç Ó Ô » ë » Â Ò ¹ ¹ È Â º » Ä Å � » Ã Å È Ä ï Û » Õ Ö Ù Å ¼ ¹ Ä » ¾ ¹ ¾ Ó Ç Ã Ô ¹ Ó Ä Å � Ó ¹ ï

ç Ø ó ½ Ó ¾ Ô ¹ Â ¿ � � Ê

Ê é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã ÊË é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë: é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã :� é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã �A é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã AD é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã D; é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã ;E é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã E@ é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã @Ê é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ê Ê Ê é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ê ÊÊ Ë é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ê ËÊ : é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ê :Ê � é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ê �Ê A é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ê AÊ D é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ê DÊ ; é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ê ;Ê E é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ê EÊ @ é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ê @Ë é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë Ë Ê é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë ÊË Ë é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë ËË : é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë :Ë � é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë �Ë A é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë AË D é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë DË ; é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë ;Ë E é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë EË @ é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã Ë @: é Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö ò Ã Ã » Õ Ö ¾ ¹ Ä Ã :

Ì ¼ Å Õ î Ö ¹ Â ¹ Ã È ¹ Ú Ã Â » Õ Ã Ã Ö ¹ ì 1 ì É Ó Ô » ë » Â Ò ó Ó Ò º ¹ Ã ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ãò Ò Ò ò Ã Ã » Õ Ö ¾ ¹ Ä Ã À ¹ ¼ ¹ Ã ¹ ò Ã Ã » Õ Ö ¾ ¹ Ä Ã 7 Å ¹ ë ò Ã Ã » Õ Ö ¾ ¹ Ä Ã


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If submitting an application with >30 subaward budgets in a single component, budgets 31 and above should be converted to PDF and included as part of the Budget Justification of the main component budget in Section K of the R&R Budget form. When subaward budgets are added to a component, the sum all subawards must be included in Line F.5 Subawards/Consortium/Contractual Costs of the budget marked Project within the component.

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ASSIST provides the ability to add up to 30 subaward budgets per component using the Add Optional Form action available from the Summary tab for the component.

ç Ø ó ½ Ó ¾ Ô ¹ Â ¿ @ Ë A ÊË ï É Á ¹ Õ Å Ù Å Õ ò Å ¾ Ç: ï B ì ¹ Ç ¹ » Â Õ Ö É Ã Â » Ã ¹ º ÍA ï Ð Â È Ã ¹ Õ Ã Å È Ä È Ù 6 Ó ¾ » Ä É Ó Ô C ¹ Õ Ã ÇD ï Ï Ä Õ ¼ Ó Ç Å È Ä È Ù ê È ¾ ¹ Ä » Ä Ò Ø Å Ä È Â Å Ã Å ¹ Ç; ï Ï Ä Õ ¼ Ó Ç Å È Ä È Ù Ì Ö Å ¼ Ò Â ¹ ÄE ï 7 ¹ Â Ã ¹ Ô Â » Ã ¹ ò Ä Å ¾ » ¼ ÇÊ Ê ï Ì È Ä Ç È Â Ã Å Ó ¾ Ñ Ì È Ä Ã Â » Õ Ã Ó » ¼ ò Â Â » Ä º ¹ ¾ ¹ Ä Ã ÇÊ Ë ï ¸ ¹ Ã Ã ¹ Â Ç È Ù É Ó Á Á È Â ÃÊ : ï ì ¹ Ç È Ó Â Õ ¹ É Ö » Â Å Ä º Ð ¼ » Ä è Ç éÊ � ï ò Á Á ¹ Ä Ò Å Ú

Ê ï Ï Ä Ã Â È Ò Ó Õ Ã Å È Ä Ã È ò Á Á ¼ Å Õ » Ã Å È ÄF G H I J K L M N O P L L P Q R H I J K S P L P Q R H T U V WX . " ' ( � . Y Z � � � # � � � � , ( #

Ð ¼ ¹ » Ç ¹ » Ã Ã » Õ Ö » Á Á ¼ Å Õ » Ô ¼ ¹ Ç ¹ Õ Ã Å È Ä Ç È Ù Ã Ö ¹ Â ¹ Ç ¹ » Â Õ Ö Á ¼ » Ä í Ô ¹ ¼ È ë ï

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Attachments typically required if Human Subjects= Yes on the Other Project Information form.

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Limited to 1 page.

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Required attachment. Limited to 1 page.

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See Section IV of the FOA for Overall and component page limits. Typically 6 or 12 pages; a small number of FOAs will specify 30 pages.

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Required if Human Subjects is Yes.

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Required if Human Subjects is Yes and exemption number is not 4.

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Required if Vertebrate Animals is Yes on the Other Project Information form.

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Overall: Required if more than one PD/PI is specified on R&R Sr./Key Person Profile form.

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Allows for up to 10 appendices. See Application Guide and announcement for restrictions. Appendices are stored separately in the eRA Commons (not as part of the application image) and are accessible to appropriate Agency staff and peer reviewers. DO NOT use Appendix attachments to circumvent page limits in other sections of the application. Such actions will be noted at time of review. See NIH Guide notice NOT-OD-11-080.

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Form Totals automatically calculated.

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Once the required fields are completed, you have the option of adding an additional study (up to 150 total).

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More than One Race recently added to this Planned Enrollment Report.

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Use this form to provide information about individuals expected to be prospectively enrolled in a proposed study.

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Once the required fields are completed, you have the option of adding an additional study (up to 150 total).

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Use this form to 1) report on recruitment progress in a previous funding period (part of the Renewal progress report) and/or 2) to provide enrollment information for new studies proposing to use an existing dataset or resource where no ongoing or future contact with participants is anticipated.


1. Introduction to Application (for RESUBMISSION applications only)

2. Candidate's Background

3. Career Goals and Objectives

4. Candidate's Plan for Career Development/ Training Activities During Award Period

7. Plans and Statements of Mentor and Co- Mentor(s)

11. Specific Aims

13. Progress Report Publication List (for RENEWAL applications only)

14. Protection of Human Subjects

15. Inclusion of Women and Minorities

5. Training in the Responsible Conduct of Research

16. Inclusion of Children

Research Plan

Statements and Letters of Support

Candidate Information

9. Description of Institutional Environment

10. Institutional Commitment to Candidate's Research Career Development

Environment and Institutional Commitment to Candidate

Human Subject Sections

6. Candidate's Plan to Provide Mentoring (as applicable)

12. * Research Strategy

Please attach applicable sections, below

Introduction (if applicable)

OMB Number: 0925-0001

8. Letters of Support from Collaborators, Contributors, and Consultants

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Required if Human Subjects is Yes.

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Required attachment. Limited to 1 page.

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Required. Check announcement for potential page limitation.

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Required.

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When provided, limited to 6 pages.

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Required. Limited to 1 page.

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Required for Resubmission and Revision applications. Limited to 1 page.

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Required.

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Required.

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Required. Limited to 6 page.

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When provided, limited to 6 pages.

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Required. Check announcement for potential page limitation.

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Attachments typically required if Human Subjects= Yes on the Other Project Information form.

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The total number of pages for Items 2-4 (Candidate's Background, Career Goals and Objectives, and Candidate's Plan for Career Development/Training Activities During Award Period) and Item 12 (Research Strategy) combined may not exceed 12 pages.

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The total number of pages for Items 2-4 (Candidate's Background, Career Goals and Objectives, and Candidate's Plan for Career Development/Training Activities During Award Period) and Item 12 (Research Strategy) combined may not exceed 12 pages. Error if total number of pages is greater than 15 and warning if total number of pages is greater than 12 and less than or equal to 15 (providing some allowance for page breaks).

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21. Appendix

17. Vertebrate Animals

18. Select Agent Research

19. Consortium/Contractual Arrangements

20. Resource Sharing Plan(s)

* Citizenship


Appendix (if applicable)

Other Research Plan Sections

U.S. Citizen or noncitizen national Permanent Resident of U.S. Pending

Permanent Resident of U.S. (If a permanent resident of the U.S., a notarized statement must be provided by the time of award)

Non-U.S. Citizen with temporary U.S. visa





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Citizenship selection required.

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Required if Vertebrate Animals is Yes on the Other Project Information form.

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'Non-U.S. Citizen with temporary U.S. visa' is not typically a valid option, though it may be accepted for K99/R00 applications.

B. Other Direct CostsTrainee Travel

Training Related Expenses

Funds Requested ($)

C. Total Direct Costs Requested (A + B)

D. Indirect CostsIndirect Cost Type

Indirect CostRate (%)

Indirect CostBase ($)

FundsRequested ($)

E. Total Direct and Indirect Costs Requested (C + D)

F. Budget Justification

Total Other Direct Costs Requested

Total Direct Costs from R&R Budget Form (if applicable)

Consortium Training Costs (if applicable)

Total Indirect Costs Requested

A. Stipends, Tuition/Fees

Undergraduate:

Single Degree

Dual Degree

Total Predoctoral

Postdoctoral:

Predoctoral:

StipendsRequested ($)

Number of TraineesTuition/Fees

Requested ($)

Other:

FullTime

ShortTerm

Totals:

Number Per Stipend Level:65

Number Per Stipend Level:

First-Year/Soph. Junior/Senior

Total Stipends + Tuition/Fees Requested

4210Non-degreeSeekingDegreeSeekingTotalPostdoctoral

1.

2.

3 7

Organizational DUNS: Budget Type: Project Subaward/Consortium

Organization Name:

Start Date: End Date:

OMB Number: 0925-0001 PHS 398 TRAINING BUDGET, Period 1



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Provide DUNS for the organization whose budget is reflected on this form.

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Use Project when providing data for the budget associated with the component's lead organization.

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The end date for each budget period must be later than the budget start date and less than or equal to the proposed project end date listed on the SF 424 (R&R) cover.

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For New and Resubmission applications, the first budget period start date must match the start date listed on the SF 424 (R&R) cover. The start date in subsequent periods must be greater than or equal to the start date on the cover.

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If Number of Trainees data is provided then corresponding Stipends Requested data must also be provided and vice versa.

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Warning if not provided.

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Indirect Cost Rate is typically 8%.

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Required.

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Budget justification is required and must cover all budget periods.

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Include sum of all attached Training Subaward Budget forms.

PHS 398 TRAINING BUDGET, Cumulative Budget

A. Stipends, Tuition/Fees

Undergraduate:

Single Degree

Dual Degree

Total Predoctoral

Postdoctoral:

Predoctoral:

StipendsRequested ($)

Tuition/FeesRequested ($)

Other:

B. Other Direct Costs

Totals:

Trainee Travel

FundsRequested ($)

C. Total Direct Costs Requested (A + B)

D. Total Indirect Costs Requested

Total Stipends + Tuition/Fees Requested

Training Related Expenses

Total Other Direct Costs Requested

Total Direct Costs from R&R Budget Form (if applicable)

E. Total Direct and Indirect Costs Requested (C + D)

Consortium Training Costs (if applicable)

Non-Degree Seeking

Degree Seeking

Total Postdoctoral


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Cumulative Budget is system generated based on budget period data provided.


TRAINING SUBAWARD BUDGET ATTACHMENT(S) FORMInstructions:

On this form, you will attach the PHS 398 Training Budget forms for all subawards in your grant application.

The means to obtain a training subaward budget attachment is provided here on this form, using the button below. In order to extract, fill, and attach each additional training subaward budget form, simply follow these steps:

• Select the button labeled "Select to Extract a Training Subaward Budget Attachment", which appears below.

• Save the file using a descriptive name, that will help you remember the content of the supplemental form that you are creating. When assigning a name to the file, please remember to give it the extension ".pdf" (for example, "Training_Subaward_Budget_MyOrganization.pdf"). If you do not name your file with the ".pdf" extension you will be unable to open it later, using your Adobe Acrobat Reader software.

• Using the Open icon in Adobe Acrobat Reader, open the new form that you have just saved.

• Enter the subawardee's training budget information, in this supplemental form. It is essentially the same as the PHS 398 Training Budget form that you see in the main body of your application.

• When you have completed entering information in the supplemental form, save it and close it.

• Return to this "PHS 398 Training Subaward Budget Attachment(s)" form.

• Attach the saved supplemental form, that you just filled in, to one of the “Attach Training Subaward” blocks provided below.

Please attach Training Subaward Budget forms, using the blocks below. Please remember that the files you attach must be PHS 398 Training Budget PDF forms, which were previously extracted using the process outlined above. Attaching any other type of file may result in the inability to submit your application to Grants.gov.

Important:

Attach Training Subaward Budget 1

















Select to Extract a Training Subaward Budget Attachment




View AttachmentDelete AttachmentAdd Attachment















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If submitting an application with >30 subaward budgets in a single component, budgets 31 and above should be converted to PDF and included as part of the Budget Justification of the main component budget in Section K of the R&R Budget form. The sum of all subaward budgets (e.g., those attached separately on this form and those provided as part of the budget justification), must be included in the Consortium Training Costs field in Other Direct Costs (Section B) of the parent PHS 398 Training Budget form.

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ASSIST provides the ability to add up to 30 subaward budgets per component using the Add Optional Form action available from the Summary tab for the component.

TRAINING SUBAWARD BUDGET ATTACHMENT(S) FORM




























PHS 398 Research Training Program Plan

Please attach applicable sections of the research training program plan, below.

1. Introduction to Application (for RESUBMISSION or REVISION only)

2. Background

3. Program Plan

4. Recruitment and Retention Plan to Enhance Diversity

5. Plan for Instruction in the Responsible Conduct of Research

6. Progress Report (for RENEWAL applications only)

7. Human Subjects

8. Vertebrate Animals

9. Select Agent Research

10. Multiple PD/PI Leadership Plan (if applicable)

11. Consortium/Contractual Arrangements

15. Appendix

13. Data Tables

14. Letters of Support

12. Participating Faculty Biosketches
















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Required.

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Required if Vertebrate Animals Used is Yes on the Other Project Information form.

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Required if Human Subjects is Yes on the Other Project Information form.

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Generally required. Check announcement instructions.

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Required attachment for Resubmission applications; limited to 3 pages. Required attachment for Revision applications; limited to 1 page.

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Required.

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Required.

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Required.

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Generally required. Check announcement. User defined bookmarks in this attachment are included with the bookmarks in the submitted application image in eRA Commons.

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Attachments 2-4 (Background, Program Plan, Recruitment and Retention Plan to Enhance Diversity and Plan for Instruction in the Responsible Conduct of Research) together can not exceed the page limitation indicated in the announcement.

Budget Type:

Enter name of Organization:

* Start Date: * End Date:

ORGANIZATIONAL DUNS:

Project Subaward/Consortium

PHS Additional Indirect Costs - Budget Period

Budget Period:


1

1

Indirect Costs

Indirect Cost Type Indirect Cost Rate (%) Indirect Cost Base ($) Funds Requested ($)

Total Indirect Costs

Budget Justification

(Only attach one file.) Add Attachment Delete Attachment View Attachment


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Optional form in Overall component. Used to gather additional indirect cost information needed from the applicant organization to correctly calculate an application's indirect costs when entire components are led by collaborating organizations.

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Add up to 4 indirect cost rates. You can combine costs associated with multiple subaward organizations in the same entry if the same indirect cost rate applies.

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The Budget Justification should explain what is included in the included indirect cost information.

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ASSIST: Use the Add Optional Form action to include the form in your Overall component.

PHS Additional Indirect Costs - Cumulative Budget

Totals ($)

Indirect Costs


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System calculated.

nih electronic multi-project applications: annotated sf424

Documents